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Energy-reduced diets supplemented with xylanase, Bacillus sp., and yeast wall maintain bone parameters, gut morphometry, economic indices, and performance of pigs Energyreduced Energy reduced xylanase sp sp. parameters morphometry indices
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Justino, Lucas Rodrigo

; Souza, Christiane Silva

; Vasconcelos, Bruno da Silva de

; Costa, Jessica Amaral

; Quaresma, Débora Vaccari

; Dilelis, Felipe

; Vieira, Antonio Assis

; Lima, Cristina Amorim Ribeiro de

Revista Brasileira de Zootecnia

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2024, Volume 53 elocation e20230046

Abstract: En | Text: En | PDF: En

ABSTRACT This study aimed to investigate the effects of xylanase (Xyl) individually or in combination with B. subtilis and B. licheniformis associated or not with yeast cell wall in pig diets with a reduction of 100 kcal/kg of metabolizable energy (ME) content. Pig performance, bone parameters, intestinal morphometry, and bioeconomic indices were evaluated. A total of 75 pigs (25 females and 50 barrows; 25.02±3.21 kg) obtained from crossing Large White × Landrace were used. The experimental design consisted of randomized blocks, with five treatments and five blocks, totaling 25 experimental units subjected to treatments: basal diet (B); basal diet with reduction of 100 kcal/kg of ME (BEM); BEM with supplementation of xylanase (0.01%; BX); BX with supplementation of direct-fed microbials (composed of B. subtilis and B. licheniformis; 0.02%; BXM); and BX supplemented with 0.10% of symbiotic (which includes B. subtilis, B. licheniformis, and yeast cell wall; BXS). There were no differences in bone parameters. The BEM diet resulted in a lower villus height:crypt depth ratio in the jejunum than that seen upon using the BXS diet as feed. In the first period, pigs fed BEM diet had a 12% higher average daily feed intake than those fed the BXM diet. There were no differences in the pig performance during the second period. Over the total period, pigs fed BEM diet had greater FCR compared with pigs fed BXM diet. The inclusion of feed additives in diets with reduced ME content contributes to the maintenance of performance and characteristics of the metacarpus and jejunum of growing pigs and provides better bioeconomic indices. Xyl (Xyl B 10 kcalkg kcal kg (ME parameters morphometry evaluated 7 (2 5 barrows 2502321 02 3 21 25.02±3.2 used blocks 2 (B) (BEM) 0.01% 001 0 01 (0.01% BX) directfed direct composed 0.02% 002 BXM) 010 0.10 which BXS. . BXS) heightcrypt height crypt period 12 1 ( 250232 25.02±3. (B (BEM 0.01 00 (0.01 0.02 0.1 25023 25.02±3 0.0 (0.0 0. 2502 25.02± (0. 250 25.02 (0 25.0 25.

https://doi.org/10.37496/rbz5320230046

The treatment of diabetic macular edema with intravitreal bevacizumab in users of the Brazilian public health system
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Ibrahim, Larissa Fouad

; Soares, Aleida Nazareth

; Costa, Lucas Assis

; Domingues, Thabata Machado Correia

; Souza, Alessandra Hubner de

Arquivos Brasileiros de Oftalmologia

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2024, Volume 87 N. 5 elocation e2024-0146

Abstract: En | Text: En | PDF: En

https://doi.org/10.5935/0004-2749.2024-0146

Sistematização de flancoplastia baseada na anatomia cirúrgica
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VILELA, MARCELA SANTOS

; DAHER, LEONARDO MARTINS COSTA

; DAHER, JOSÉ CARLOS

; DALBOSCO, LUCAS VARGAS

; AQUINO, LUCAS ALBUQUERQUE

; SOARES, IGOR MOURA

; GOMES, SAULO FRANCISCO DE ASSIS

Revista Brasileira de Cirurgia Plástica

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2024, Volume 39 N. 3 elocation e0874

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: O estudo explora a cirurgia de contorno corporal em pacientes submetidos a cirurgias bariátricas. Nos últimos anos, esse tipo de intervenção cirúrgica ganhou destaque devido ao aumento na busca por procedimentos reparadores após significativa perda de peso. O texto enfatiza a importância da flancoplastia, técnica que visa melhorar o contorno corporal. Métodos: Foi realizada revisão da literatura para elucidação da anatomia da gordura profunda da fáscia toracolombar, e feito um paralelo com a técnica de flancoplastia utilizada em nosso serviço em pacientes pós-bariátricos submetidos a abdominoplastia 360° ou 270° no Hospital Daher Lago Sul, em Brasília-D F. Resultados: A lipoaspiração profunda dos flancos, muitas vezes necessária em cirurgias de contorno corporal, pode não ser suficiente para retirar a gordura profunda à fáscia toracolombar e durante esse procedimento observa-se risco aumentado de lesões retroperitoneais. No entanto, a flancoplastia, que envolve a ressecção da gordura profunda à fáscia toracolombar, demonstrou proporcionar resultados satisfatórios e minimizar esses riscos. O estudo enfoca a importância do conhecimento anatômico preciso, destacando a relevância da flancoplastia como uma técnica valiosa para melhorar os resultados estéticos e reduzir complicações em pacientes pós-bariátricos, complementando a cirurgia bariátrica e melhorando a qualidade de vida do paciente. Introdução bariátricas anos peso Métodos pósbariátricos pós bariátricos 360 270 Sul BrasíliaD Brasília D F Resultados flancos observase observa se retroperitoneais entanto riscos preciso pósbariátricos, bariátricos, paciente 36 27 3 2

ABSTRACT Introduction: The study explores body contouring surgery in patients undergoing bariatric surgery. In recent years, this type of surgical intervention has gained prominence due to the increase in the search for reparative procedures after significant weight loss. The text emphasizes the importance of flankplasty, a technique that aims to improve body contour. Methods: A literature review was carried out to elucidate the anatomy of the deep fat of the thoracolumbar fascia, and a parallel was made with the flankplasty technique used in our service in post-bariatric patients undergoing 360° or 270° abdominoplasty at Daher Lago Sul Hospital, in Brasília-DF. Results: Deep liposuction of the flanks, often necessary in body contouring surgeries, may not be sufficient to remove fat deep into the thoracolumbar fascia and during this procedure, there is an increased risk of retroperitoneal injuries. However, flankplasty, which involves resection of fat deep into the thoracolumbar fascia, has been shown to provide satisfactory results and minimize these risks. Conclusion: The study focuses on the importance of precise anatomical knowledge, highlighting the relevance of flankplasty as a valuable technique to improve aesthetic results and reduce complications in post-bariatric patients, complementing bariatric surgery and improving the patient’s quality of life. Introduction years loss contour Methods postbariatric post 360 270 Hospital BrasíliaDF. BrasíliaDF Brasília DF. DF Brasília-DF Results flanks surgeries procedure injuries However risks Conclusion knowledge patient s life 36 27 3 2

https://doi.org/10.5935/2177-1235.2024rbcp0874-pt

Safety of CoronaVac and ChAdOx1 vaccines against SARS-CoV-2 in patients with rheumatoid arthritis: data from the Brazilian multicentric study safer ChAdOx SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- arthritis SARS-CoV
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Cruz, Vitor Alves

; Guimarães, Camila

; Rêgo, Jozelia

; Machado, Ketty Lysie Libardi Lira

; Miyamoto, Samira Tatiyama

; Burian, Ana Paula Neves

; Dias, Laiza Hombre

; Pretti, Flavia Zon

; Batista, Danielle Cristina Filgueira Alves

; Mill, José Geraldo

; Oliveira, Yasmin Gurtler Pinheiro de

; Gadelha, Carolina Strauss Estevez

; Gouveia, Maria da Penha Gomes

; Moulin, Anna Carolina Simões

; Souza, Bárbara Oliveira

; Aguiar, Laura Gonçalves Rodrigues

; Vieira, Gabriel Smith Sobral

; Grillo, Luiza Lorenzoni

; Lima, Marina Deorce de

; Pasti, Laís Pizzol

; Surlo, Heitor Filipe

; Faé, Filipe

; Moulaz, Isac Ribeiro

; Macabú, Mariana de Oliveira

; Ribeiro, Priscila Dias Cardoso

; Magalhães, Vanessa de Oliveira

; Aguiar, Mariana Freitas de

; Biegelmeyer, Erika

; Peixoto;, Flávia Maria Matos Melo Campos

; Kayser, Cristiane

; Souza, Alexandre Wagner Silva de

; Castro, Charlles Heldan de Moura

; Ribeiro, Sandra Lúcia Euzébio

; Telles, Camila Maria Paiva França

; Bühring, Juliana

; Lima, Raquel Lima de

; Santos, Sérgio Henrique Oliveira Dos

; Dias, Samuel Elias Basualto

; Melo, Natália Seixas de

; Sanches, Rosely Holanda da Silva

; Boechat, Antonio Luiz

; Sartori, Natália Sarzi

; Hax, Vanessa

; Dória, Lucas Denardi

; Rezende, Rodrigo Poubel Vieira de

; Baptista, Katia Lino

; Fortes, Natália Rodrigues Querido

; Melo, Ana Karla Guedes de

; Melo, Tâmara Santos

; Vieira, Rejane Maria Rodrigues de Abreu

; Vieira, Adah Sophia Rodrigues

; Kakehasi, Adriana Maria

; Tavares, Anna Carolina Faria Moreira Gomes

; Landa, Aline Teixeira de

; Costa, Pollyana Vitoria Thomaz da

; Azevedo, Valderilio Feijó

; Martins-Filho, Olindo Assis

; Peruhype-Magalhães, Vanessa

; Pinheiro, Marcelo de Medeiros

; Monticielo, Odirlei André

; Reis-neto, Edgard Torres Dos

; Ferreira, Gilda Aparecida

; Souza, Viviane Angelina de

; Teixeira-Carvalho, Andréa

; Xavier, Ricardo Machado

; Sato, Emilia Inoue

; Valim, Valeria

; Pileggi, Gecilmara Salviato

; Silva, Nilzio Antonio da

Advances in Rheumatology

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2024, Volume 64 elocation 58

Abstract: En | Text: En | PDF: En

Abstract Background Patients with immune-mediated rheumatic diseases (IMRDs) have been prioritized for COVID-19 vaccination to mitigate the infection severity risks. Patients with rheumatoid arthritis (RA) are at a high risk of severe COVID-19 outcomes, especially those under immunosuppression or with associated comorbidities. However, few studies have assessed the safety of the COVID-19 vaccine in patients with RA. Objective To evaluate the safety of vaccines against SARS-CoV-2 in patients with RA. Methods This data are from the study “Safety and Efficacy on COVID-19 Vaccine in Rheumatic Diseases,” a Brazilian multicentric prospective phase IV study to evaluate COVID-19 vaccine in IMRDs in Brazil. Adverse events (AEs) in patients with RA of all centers were assessed after two doses of ChAdOx1 (Oxford/AstraZeneca) or CoronaVac (Sinovac/Butantan). Stratification of postvaccination AEs was performed using a diary, filled out daily and returned at the end of 28 days for each dose. Results A total of 188 patients with RA were include, 90% female. CoronaVac was used in 109 patients and ChAdOx1 in 79. Only mild AEs were observed, mainly after the first dose. The most common AEs after the first dose were pain at the injection (46,7%), headache (39,4%), arthralgia (39,4%), myalgia (30,5%) and fatigue (26,6%), and ChAdOx1 had a higher frequency of pain at the injection (66% vs 32 %, p < 0.001) arthralgia (62% vs 22%, p < 0.001) and myalgia (45% vs 20%, p < 0.001) compared to CoronaVac. The more common AEs after the second dose were pain at the injection (37%), arthralgia (31%), myalgia (23%), headache (21%) and fatigue (18%). Arthralgia (41,4% vs 25%, p = 0.02) and pain at injection (51,4% vs 27%, p = 0.001) were more common with ChAdOx1. No serious AEs were related. With Regard to RA activity level, no significant difference was observed between the three time periods for both COVID-19 vaccines. Conclusion In the comparison between the two immunizers in patients with RA, local reactions and musculoskeletal symptoms were more frequent with ChAdOx1 than with CoronaVac, especially after the first dose. In summary, the AE occurred mainly after the first dose, and were mild, like previous data from others immunizing agents in patients with rheumatoid arthritis. Vaccination did not worsen the degree of disease activity. immunemediated immune mediated (IMRDs COVID19 COVID 19 COVID-1 risks (RA outcomes comorbidities However SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- Safety Diseases, Diseases Brazil (AEs ChAdOx Oxford/AstraZeneca OxfordAstraZeneca Oxford AstraZeneca (Oxford/AstraZeneca Sinovac/Butantan. SinovacButantan Sinovac/Butantan . Sinovac Butantan (Sinovac/Butantan) diary 18 include 90 female 10 79 46,7%, 467 46,7% , 46 7 (46,7%) 39,4%, 394 39,4% 39 4 (39,4%) 30,5% 305 30 5 (30,5% 26,6%, 266 26,6% 26 6 (26,6%) 66% 66 (66 3 % 0.001 0001 0 001 62% 62 (62 22 22% 45% 45 (45 20 20% 37%, 37 37% (37%) 31%, 31 31% (31%) 23%, 23 23% (23%) 21% 21 (21% 18%. 18% (18%) 41,4% 414 41 (41,4 25 25% 0.02 002 02 51,4% 514 51 (51,4 27 27% related level summary COVID1 1 COVID- SARS-CoV (Sinovac/Butantan 9 46,7 (46,7% 39,4 (39,4% 30,5 (30,5 26,6 (26,6% (6 0.00 000 00 (4 (37% (31% (23% (21 (18% 41,4 (41, 0.0 51,4 (51, 46, (46,7 39, (39,4 30, (30, 26, (26,6 ( (37 (31 (23 (2 (18 41, (41 0. 51, (51 (46, (39, (30 (26, (3 (1 (5 (46 (39 (26

https://doi.org/10.1186/s42358-024-00397-5

A framework to evaluate and compare synthetic streamflow scenario generation models
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Treistman, Felipe

; Penna, Débora Dias Jardim

; Khenayfis, Lucas de Souza

; Cavalcante, Nelson Bernardo Rodrigues

; Souza Filho, Francisco de Assis de

; Rocha, Renan Vieira

; Estácio, Ályson Brayner

; Rolim, Larissa Zaira Rafael

; Pontes Filho, João Dehon de Araújo

; Porto, Victor Costa

; Guimarães, Sullyandro Oliveira

; Pessanha, José Francisco Moreira

; Almeida, Victor Andrade de

; Chan, Priscilla Dafne Shu

; Lappicy, Thiago

; Lima, Carlos Henrique Ribeiro

; Detzel, Daniel Henrique Marco

; Bessa, Marcelo Rodrigues

RBRH

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2023, Volume 28 elocation e43

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO A geração de cenários sintéticos de vazões afluentes é particularmente importante em países como o Brasil, onde a geração de energia hidrelétrica desempenha um papel fundamental e é crucial lidar adequadamente com a incerteza da vazão futura. Este artigo apresenta um esforço colaborativo do setor elétrico brasileiro para aprimorar os modelos de geração de cenários de vazão, com foco em horizontes de até um ano. Cinco instituições propuseram metodologias diversas e a sua eficácia foi avaliada através de uma avaliação comparativa estruturada. Os resultados revelam os pontos fortes e as áreas de possíveis aprimoramentos em cada modelo. O modelo GHCen apresentou o melhor desempenho, destacando-se nas análises de curto prazo e de média móvel, enquanto o modelo PARX demonstrou desempenho superior em regiões específicas do Brasil. O PAR(p)-A, metodologia oficial no Brasil, foi o segundo melhor modelo na análise de médias móveis. Este artigo oferece informações valiosas para países que enfrentam desafios semelhantes de programação hidrotérmica e geração de cenários. Brasil futura ano estruturada destacandose destacando se móvel PARpA, PARpA PAR p A, PAR(p)-A móveis

ABSTRACT Synthetic streamflow scenario generation is particularly important in countries like Brazil, where hydroelectric power generation plays a key role and properly handling the uncertainty of future streamflow is crucial. This paper showcases a collaborative effort within the Brazilian electrical sector to enhance streamflow scenario models, focusing on horizons up to one year. Five institutions proposed diverse methodologies, and their effectiveness was evaluated using a comparative framework. The results reveal the strengths and areas for improvement in each model. GHCen emerged as the top performer, excelling in both short-term and moving average analyses, while the PARX model demonstrated superior performance in specific regions. The PAR(p)-A, which is the official methodology in Brazil, was the second-best model in the moving average analysis. This research offers valuable insights for countries facing similar hydrothermal scheduling and scenario generation challenges. Brazil crucial models year methodologies framework performer shortterm short term analyses regions PARpA, PARpA PAR p A, A PAR(p)-A secondbest second best analysis challenges

https://doi.org/10.1590/2318-0331.282320230115

SÍNTESE, ATIVIDADE ANTILESHMANIA E CITOTÓXICA DE HIDRAZONAS DERIVADAS DE ALDEÍDOS NATURAIS
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Souza, Débora Caroline Marques de

; Sousa, Valéria Carlos de

; Cruz, Lucas Pereira Lima da

; Carneiro, Sabrina Maria Portela

; Alves, Michel Muálem de Moraes

; Carvalho, Fernando Aécio de Amorim

; Costa, Marcília Pinheiro da

; Corrêa, Cíntia Marques

; Gonsalves, Arlan de Assis

; Araújo, Cleônia Roberta Melo

Química Nova

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jan 2020, Volume 43 N. 1 Pages 50 - 57

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Leishmaniasis is endemic anthropozoonosis considered to be a severe public health problem. The treatment with pentavalent antimonials presents high toxicity motivating the search for effective and less toxic drugs. Hydrazones and N-acylhydrazones are functional groups that are prominent in Medicinal Chemistry, including as antiprotozoals. In this context, five hydrazones derived from the natural aldehydes were synthesized and the molecular structures were suitably determined to employ uni and bidimensional 1H and 13C NMR techniques. The antileishmanial activity of all hydrazones was determined against promastigote forms of Leishmania amazonensis, and the compounds HDZ-3, HDZ-4, and HDZ-5 showed the best results, with IC50 of 9.00, 38.10 and 26.30 µM, respectively. In the cytotoxic evaluation against RAW macrophages, HDZ-4 presented the least cytotoxic (CC50 = 222.24 µM) and the higher selectivity. Lipinski’s descriptors of the hydrazones were calculated, and the compounds HDZ-3 and HDZ-5 were more promising. These hydrazones are hybrids of natural aldehydes with drugs, the first is the result of the junction of the cinnamaldehyde with isoniazid, and the second of the vanillin with hydralazine. The results highlighted the Markush isonicotinoylhydrazone and phthalazinylhydrazone groups, molecular structures that are present in HDZ-3 and HDZ-5 and are therefore considered innovators in the development of antileishmanial drugs.

https://doi.org/10.21577/0100-4042.20170440 687 downloads

Increased platelet distribution width and reduced IL-2 and IL-12 are associated with thrombocytopenia in Plasmodium vivax malaria
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Costa, Allyson Guimarães

; Chaves, Yury Oliveira

; Teixeira-Carvalho, Andréa

; Ramasawmy, Rajendranath

; Antonelli, Lis Ribeiro Valle

; Barbosa, Lucas

; Balieiro, Antonio

; Monteiro, Wuelton Marcelo

; Mourão, Maria Paula

; Lacerda, Marcus Vinicius Guimarães

; Martins-Filho, Olindo Assis

; Costa, Fabio Trindade Maranhão

; Malheiro, Adriana

; Nogueira, Paulo Afonso

Memórias do Instituto Oswaldo Cruz

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2020, Volume 115 elocation e200080

Abstract: En | Text: En | PDF: En

BACKGROUND Thrombocytopenia in malaria involves platelet destruction and consumption; however, the cellular response underlying this phenomenon has still not been elucidated. OBJECTIVE To find associations between platelet indices and unbalanced Th1/Th2/Th17 cytokines as a response to thrombocytopenia in Plasmodium vivax infected (Pv-MAL) patients. METHODS Platelet counts and quantification of Th1/Th2/Th17 cytokine levels were compared in 77 patients with uncomplicated P. vivax malaria and 37 healthy donors from the same area (endemic control group - ENCG). FINDINGS Thrombocytopenia was the main manifestation in 55 patients, but was not associated with parasitaemia. The Pv-MAL patients showed increases in the mean platelet volume (MPV), which may be consistent with larger or megaplatelets. Contrary to the findings regarding the endemic control group, MPV and platelet distribution width (PDW) did not show an inverse correlation, due the increase in the heterogeneity of platelet width. In addition, the Pv-MAL patients presented increased IL-1β and reduced IL-12p70 and IL-2 serum concentrations. Furthermore, the reduction of these cytokines was associated with PDW values. MAIN CONCLUSIONS Our data demonstrate that an increase in MPV and the association between reductions of IL-2 and IL-12 and PDW values may be an immune response to thrombocytopenia in uncomplicated P. vivax malaria.

https://doi.org/10.1590/0074-02760200080 790 downloads

Asymptomatic Leishmania infection in blood donors from a major blood bank in Northeastern Brazil: a cross-sectional study
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Silva, Lucas Portela

; Montenegro, Silvia

; Werkauser, Roberto

; Sales, Kamila Gaudêncio da Silva

; Soares, Fábia Carla Silva

; Costa, Vlaudia Maria Assis

; Bezerra, Ana Cristina

; Pinto, Maria Betania do Amaral

; Ferreira, Suzany Maria

; Neitzke-Abreu, Herintha Coeto

; Dantas-Torres, Filipe

; Lima Junior, Manoel Sebastião da Costa

Revista do Instituto de Medicina Tropical de São Paulo

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2020, Volume 62 elocation e92

Abstract: En | Text: En | PDF: En

ABSTRACT This study has estimated the risk of Leishmania transmission via blood transfusion in one of the largest blood banks in Northeastern Brazil, where visceral leishmaniasis is endemic. Five hundred blood samples from donors were tested for circulating Leishmania spp. DNA by real-time PCR. Positive samples were tested by a species-specific conventional PCR targeting Leishmania infantum . Overall, 6.2% (95% CI: 4.1–8.3%) of the samples carried Leishmania DNA and in one sample the species was confirmed as L. infantum . No statistically significant differences were found in relation to gender, sex, education level, incomeas well as the place of residence between positive and negative blood donors. Our results confirm the presence of asymptomatic Leishmania carriers among blood donors in a large blood bank in Northeastern Brazil. Considering the studied population, we estimate that for every 1,000 blood donors screened, 41 to 83 will be positive for Leishmania DNA. This finding reinforces the urgent need for elaborating specific Blood bank guidelines to allow the early detection of asymptomatic Leishmania carriers among blood donors before their blood products are transfused to uninfected individuals.

https://doi.org/10.1590/s1678-9946202062092 588 downloads

Atualização da Diretriz de Ressuscitação Cardiopulmonar e Cuidados Cardiovasculares de Emergência da Sociedade Brasileira de Cardiologia - 2019
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Bernoche, Claudia

; Timerman, Sergio

; Polastri, Thatiane Facholi

; Giannetti, Natali Schiavo

; Siqueira, Adailson Wagner da Silva

; Piscopo, Agnaldo

; Soeiro, Alexandre de Matos

; Reis, Amélia Gorete Afonso da Costa

; Tanaka, Ana Cristina Sayuri

; Thomaz, Ana Maria

; Quilici, Ana Paula

; Catarino, Andrei Hilário

; Ribeiro, Anna Christina de Lima

; Barreto, Antonio Carlos Pereira

; Azevedo Filho, Antonio Fernando Barros de

; Pazin Filho, Antonio

; Timerman, Ari

; Scarpa, Bruna Romanelli

; Timerman, Bruno

; Tavares, Caio de Assis Moura

; Martins, Cantidio Soares Lemos

; Serrano Junior, Carlos Vicente

; Malaque, Ceila Maria Sant’Ana

; Pisani, Cristiano Faria

; Batista, Daniel Valente

; Leandro, Daniela Luana Fernandes

; Szpilman, David

; Gonçalves, Diego Manoel

; Paiva, Edison Ferreira de

; Osawa, Eduardo Atsushi

; Lima, Eduardo Gomes

; Adam, Eduardo Leal

; Peixoto, Elaine

; Evaristo, Eli Faria

; Azeka, Estela

; Silva, Fabio Bruno da

; Wen, Fan Hui

; Ferreira, Fatima Gil

; Lima, Felipe Gallego

; Fernandes, Felipe Lourenço

; Ganem, Fernando

; Galas, Filomena Regina Barbosa Gomes

; Tarasoutchi, Flavio

; Souza, Germano Emilio Conceição

; Feitosa Filho, Gilson Soares

; Foronda, Gustavo

; Guimarães, Helio Penna

; Abud, Isabela Cristina Kirnew

; Leite, Ivanhoé Stuart Lima

; Linhares Filho, Jaime Paula Pessoa

; Moraes Junior, João Batista de Moura Xavier

; Falcão, João Luiz Alencar de Araripe

; Ramires, Jose Antônio Franchini

; Cavalini, José Fernando

; Saraiva, José Francisco Kerr

; Abrão, Karen Cristine

; Pinto, Lecio Figueira

; Bianchi, Leonardo Luís Torres

; Lopes, Leonardo Nícolau Geisler Daud

; Piegas, Leopoldo Soares

; Kopel, Liliane

; Godoy, Lucas Colombo

; Tobase, Lucia

; Hajjar, Ludhmila Abrahão

; Dallan, Luís Augusto Palma

; Caneo, Luiz Fernando

; Cardoso, Luiz Francisco

; Canesin, Manoel Fernandes

; Park, Marcelo

; Rabelo, Marcia Maria Noya

; Malachias, Marcus Vinícius Bolívar

; Gonçalves, Maria Aparecida Batistão

; Almeida, Maria Fernanda Branco de

; Souza, Maria Francilene Silva

; Favarato, Maria Helena Sampaio

; Carrion, Maria Julia Machline

; Gonzalez, Maria Margarita

; Bortolotto, Maria Rita de Figueiredo Lemos

; Macatrão-Costa, Milena Frota

; Shimoda, Mônica Satsuki

; Oliveira-Junior, Mucio Tavares de

; Ikari, Nana Miura

; Dutra, Oscar Pereira

; Berwanger, Otávio

; Pinheiro, Patricia Ana Paiva Corrêa

; Reis, Patrícia Feitosa Frota dos

; Cellia, Pedro Henrique Moraes

; Santos Filho, Raul Dias dos

; Gianotto-Oliveira, Renan

; Kalil Filho, Roberto

; Guinsburg, Ruth

; Managini, Sandrigo

; Lage, Silvia Helena Gelas

; Yeu, So Pei

; Franchi, Sonia Meiken

; Shimoda-Sakano, Tania

; Accorsi, Tarso Duenhas

; Leal, Tatiana de Carvalho Andreucci

; Guimarães, Vanessa

; Sallai, Vanessa Santos

; Ávila, Walkiria Samuel

; Sako, Yara Kimiko

Arquivos Brasileiros de Cardiologia

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sep 2019, Volume 113 N. 3 Pages 449 - 663

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.5935/abc.20190203 54793 downloads

10.

Letramento funcional em saúde nos portadores de doenças cardiovasculares crônicas
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Chehuen Neto, José Antonio

; Costa, Lucas Assis

; Estevanin, Gabriela Mazorque

; Bignoto, Tomás Costa

; Vieira, Camila Isabela Ribeiro

; Pinto, Frederico Afonso Rios

; Ferreira, Renato Erothildes

Ciência & Saúde Coletiva

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mar 2019, Volume 24 N. 3 Pages 1121 - 1132

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Letramento Funcional em Saúde (LFS) é a capacidade de obter, processar e compreender informações de forma a tomar decisões apropriadas quanto ao autocuidado, definido pela Organização Mundial de Saúde como um determinante social da saúde. Sua avaliação tem importância especial em portadores de Doenças Crônicas não Transmissíveis, pela necessidade de cuidados permanentes em saúde. Os objetivos são avaliar o LFS em portadores de doenças cardiovasculares crônicas e possíveis implicações no entendimento da doença e orientações médicas e na adesão a medidas propostas por profissionais de saúde. Pesquisa transversal e quantitativa aplicando-se o instrumento S-TOFHLA e um questionário estruturado em 345 pacientes de um ambulatório de doenças cardiovasculares em Juiz de Fora. Menos da metade (49,3%) da amostra apresentou LFS adequado. O LFS satisfatório associou-se a menor idade e maior escolaridade. O baixo LFS mostrou influenciar o déficit de compreensão da doença e de orientações médicas e o hábito menor de questionar os profissionais. Houve alta prevalência de LFS inadequado na amostra, associado a prejuízo no entendimento da doença e de instruções médicas, expondo a necessidade de otimizar a comunicação médica nesse grupo.

Abstract Functional Health Literacy (FHL) is the ability to retrieve, process and understand information in order to make appropriate decisions regarding self-care, defined by the World Health Organization as a social determinant of health. Its evaluation is important especially between patients with noncommunicable chronic diseases, given the need of permanent health care. This paper aims to evaluate the FHL in patients with chronic cardiovascular diseases and possible implications to the understanding of the disease and medical instructions and adherence to the measures proposed by health professionals. This is a cross-sectional and quantitative study with the application of tool S-TOFHLA and a structured questionnaire on 345 patients of a cardiovascular disease outpatient service in Juiz de Fora. Less than a half (49.3%) of the sample showed adequate FHL. Satisfactory FHL was associated with lower ageand higher schooling. Lower FHL evidenced that it can influence the impaired comprehension of the disease and medical instructions and the rare habit to question professionals. A high prevalence of inadequate FHL was identified in our sample and was associated with the impaired understanding of the disease and medical instructions, showing the need to streamline medical communication in this group.

https://doi.org/10.1590/1413-81232018243.02212017 3098 downloads

11.

Assumptions of good practices in home care for the elderly: a systematic review
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Rodrigues, Rosalina Aparecida Partezani

; Bueno, Alexandre de Assis

; Casemiro, Francine Golghetto

; Cunha, Alan Nogueira da

; Carvalho, Lucas Pelegrini Nogueira de

; Almeida, Vanessa Costa

; Reis, Nayara Araújo dos

; Seredynskyj, Fernanda Laporti

Revista Brasileira de Enfermagem

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2019, Volume 72 Suppl. 2 Pages 302 - 310

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: sintetizar o conhecimento produzido sobre as melhores práticas de enfermagem no cuidado de longa duração ao idoso no domicílio, a fim de favorecer o envelhecimento saudável. Método: Revisão sistemática, segundo proposta do Joanna Briggs Institute, sem restrição de datas, nos idiomas inglês, português e espanhol, nas bases de dados PubMed, CINAHL, LILACS, Embase e Scopus. Resultados: De um total de 453 artigos identificados, 16 foram incluídos na revisão: sete qualitativos e nove quantitativos, publicados entre 1996 e 2015. A síntese dos dados identificados como melhores práticas evidencia como pressupostos o cuidado centrado no idoso e a inclusão do idoso, da família e dos enfermeiros como agentes deste cuidado. Conclusão: As boas práticas em enfermagem gerontológica na atenção domiciliar, segundo as evidências, dependem fundamentalmente de constantes planejamentos e reorganizações, para que sejam de fato inclusivas e contextualizadas. Dessa forma, a produção do cuidado será fundamentada e orientada ao idoso, com base em suas necessidades específicas e globais, o que favorece um processo de envelhecimento saudável e ativo.

ABSTRACT Objective: To synthesize the knowledge produced on best nursing practices in long-term care for elderly at home, in order to promote healthy aging. Method: A systematic review, based on the Joanna Briggs Institute’s proposal: without restriction of dates; in the English, Portuguese and Spanish languages; conducted in PubMed, CINAHL, LILACS, Embase and Scopus databases. Results: Among 453 articles identified, 16 were included in the review: seven qualitative and nine quantitative, published between 1996 and 2015. The synthesis of the data identified as best practices identifies a premise of care centered on the elderly and the inclusion of the elderly, family and nurses as agents of this care. Conclusion: According to evidence, good practices in gerontological and nursing home care fundamentally depend on constant planning and reorganization, so that they are indeed comprehensive and contextualized. Thus, providing care will be reasoned by and driven to the elderly, based on their specific and global needs, favoring a process of healthy and active aging.

RESUMEN Objetivo: Sintetizar el conocimiento producido sobre las mejores prácticas enfermeras en el cuidado a largo plazo para los adultos mayores en el hogar, a fin de promover un envejecimiento saludable. Método: Una revisión sistemática, basada en la propuesta del Instituto Joanna Briggs, sin restricción de fechas, en los idiomas inglés, portugués y español, realizada en las bases de datos PubMed, CINAHL, LILACS, Embase y Scopus. Resultados: Entre los 453 artículos identificados, 16 se incluyeron en la revisión: siete cualitativos y nueve cuantitativos, publicados entre 1996 y 2015. La síntesis de los datos se identificó como las mejores prácticas evidencian como premisas la atención centrada en los adultos mayores y su inclusión, así como de los familiares y enfermeras como agentes de este cuidado. Conclusión: De acuerdo con las evidencias, las buenas prácticas en gerontología y en asilos, dependen esencialmente de la planificación y reorganización constantes, por lo que son integrales y contextualizadas. Por lo tanto, la atención se razonará y se dirigirá a los adultos mayores, en función de sus necesidades específicas y globales, lo que favorece un proceso de envejecimiento saludable y activo.

https://doi.org/10.1590/0034-7167-2018-0445 2588 downloads

12.

Assumptions of good practices in home care for the elderly: a systematic review
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Rodrigues, Rosalina Aparecida Partezani

; Bueno, Alexandre de Assis

; Casemiro, Francine Golghetto

; Cunha, Alan Nogueira da

; Carvalho, Lucas Pelegrini Nogueira de

; Almeida, Vanessa Costa

; Reis, Nayara Araújo dos

; Seredynskyj, Fernanda Laporti

Revista Brasileira de Enfermagem

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2019, Volume 72 Suppl. 2 Pages 302 - 310

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

https://doi.org/10.1590/0034-7167-2018-0445 46 downloads

13.

Letramento funcional em saúde nos portadores de doenças cardiovasculares crônicas
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Chehuen Neto, José Antonio

; Costa, Lucas Assis

; Estevanin, Gabriela Mazorque

; Bignoto, Tomás Costa

; Vieira, Camila Isabela Ribeiro

; Pinto, Frederico Afonso Rios

; Ferreira, Renato Erothildes

Ciência & Saúde Coletiva

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2019, Volume 24 N. 3 Pages 1121 - 1132

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-81232018243.02212017

14.

In vivo effect of diflubenzuron, administered via mineral salt supplementation, against Haematobia irritans and Rhipicephalus microplus parasitizing cattle
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Cruz, Breno Cayeiro

; Gomes, Lucas Vinicius Costa

; Maciel, Willian Giquelin

; Felippelli, Gustavo

; Santos, Isabella Barbosa dos

; Cruvinel, Leonardo Bueno

; Couto, Luiz Fellipe Monteiro

; Bastos, Thiago Souza Azeredo

; Cavalcante, Alliny Souza de Assis

; Nicaretta, João Eduardo

; Soares, Vando Edésio

; Costa, Alvimar José da

; Lopes, Welber Daniel Zanetti

Revista Brasileira de Parasitologia Veterinária

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dec 2018, Volume 27 N. 4 Pages 545 - 554

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo deste estudo foi avaliar a eficácia do diflubenzuron, administrado via suplementação mineral, contra Haematobia irritans parasitando bovinos, em dois testes à campo. Concomitantemente, foi realizado testes em estábulo para determinar os efeitos de uma formulação diferente, com o mesmo princípio ativo, contra Rhipicephalus microplus , bem como a ação do diflubenzuron nos parâmetros reprodutivos de fêmeas de R. microplus recolhidas após desprendimento natural do hospedeiro bovino. Contra H. irritans, foi observado que foram baixos (≤ 31,3% ou 44,6%) ou nulos (0,0%) os índices de eficácia do diflubenzuron. A eficácia anti-R. microplus do diflubenzuron, observada em intervalos semanais, variaram de 0,0% a 13,7% durante todo o período experimental. Com relação aos parâmetros reprodutivos das fêmeas de R. microplus recolhidas, foi observada eficácia nula (0,0%) para o diflubenzuron. Conclui-se que as diferentes formulações administradas via sal mineral no atual estudo, contra H. irritans e R. microplus parasitando bovinos, não apresentaram eficácia satisfatória. Este agente também não mostrou efeito deletério sobre os parâmetros reprodutivos de fêmeas de R. microplus.

Abstract This study involved two field trials with the aim of evaluating the efficacy of diflubenzuron, via mineral supplementation, against Haematobia irritans parasitizing cattle. Concomitantly with the main trial, a stall test was conducted to ascertain the effects of a different formulation with the same active ingredient against Rhipicephalus microplus, along with the action of diflubenzuron on the reproductive parameters of R. microplusfemales that had naturally detached from cattle. Against H. irritans, it was observed that the efficacy indexes fordiflubenzuron were low (≤ 31.3% or 44.6%) or null (0.0%) throughout the study. The anti- R. microplus efficacy of diflubenzuron, at weekly intervals, ranged from 0.0 to 13.7% over the entire experimental period. Null efficacy (0.0%) was registered for diflubenzuron in relation to the reproductive parameters of R. microplusfemales that had naturally detached from cattle. The different diflubenzuron formulations, administered via mineral salt supplementation, did not show satisfactory efficacy indexes against H. irritans and R. microplus parasitizing cattle, within the experimental design of the present study. In addition, this agent did not present any deleterious effects on the reproductive parameters of R. microplus females.

https://doi.org/10.1590/s1984-296120180084 1146 downloads

15.

Prevalence of bovine fascioliasis, areas at risk and ensuing losses in the state of Goiás, Brazil
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Aquino, Fernanda Martins de

; Soares, Vando Edésio

; Rossi, Gabriel Augusto Marques

; Nicaretta, João Eduardo

; Bastos, Thiago de Souza Azeredo

; Cruvinel, Leonardo Bueno

; Couto, Luiz Fellipe Monteiro

; Cavalcante, Alliny Souza de Assis

; Felippelli, Gustavo

; Cruz, Breno Cayeiro

; Maciel, Willian Giquelim

; Gomes, Lucas Vinicius Costa

; Lopes, Welber Daniel Zanetti

Revista Brasileira de Parasitologia Veterinária

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jun 2018, Volume 27 N. 2 Pages 123 - 130

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O presente estudo objetivou determinar a prevalência e a distribuição espacial das áreas em risco para fasciolose bovina no Estado de Goiás, região Centro-Oeste do Brasil, entre 2007 a 2014; avaliando as associações de variáveis epidemiológicas com ocorrências da Fasciola hepatica em animais; e estimar as perdas econômicas deste parasito em bovinos. Pode-se concluir que de 23.255.979 bovinos abatidos, a prevalência média de F. hepatica durante o período avaliado foi de 0,0026% (IC 95%: 0,0024-0,0028). No Estado de Goiás, em aproximadamente 10 anos (desde quando este parasito foi encontrado pela primeira vez por outros pesquisadores em 2007), F. hepatica foi diagnosticada em 168 novos municípios. Utilizando-se a análise de regressão logística, o tamanho do rebanho apresentou-se como um fator de risco significativo (OR= 1,21; IC 95% 1,1022-1,4510; p≤0,05) para os bovinos se infectarem por F. hepatica no referido Estado. O prejuízo, devido à condenação de fígados com Fasciola nos bovinos no Estado de Goiás, foi de R$ 15.072,75 (US 4.785). Novos estudos precisam ser conduzidos nessas regiões, com o objetivo de identificar a presença de hospedeiros intermediários infectados, que podem servir como fonte de infecção por F. hepatica para hospedeiros definitivos.

Abstract The present study had to determine the prevalence and spatial distribution of areas at risk of bovine fascioliasis in the state of Goiás, central-western Brazil between 2007 and 2014; to evaluate the associations of some epidemiological variables with occurrences of Fasciola hepatica in animals; and to estimate the economic losses that this parasite on the cattle industry. It could be concluded that of 23,255,979 animals slaughtered, the average prevalence of F. hepatica in cattle in Goiás during the period evaluated was 0.0026% (95% CI: 0.0024-0.0028). In the State of Goias, in about then years (since when this parasite was found for the first time by other researchers in 2007), F. hepatica was diagnosed in 168 new municipalities. Using the regression analysis, the effective bovine herd size was a significant risk factor (OR= 1.21; 95% CI 1.1022-1.4510; p ≤ 0.05) for cattle to be infected with fascioliasis in the state of Goiás. The cattle-rearing industry lost approximately R$ 15,072.75 (US$ 4,785) due to condemn of livers with Fasciola in the state of Goiás. New studies need to be conducted in these regions, with the aim to identify the likelihood of presence of intermediate hosts, which might serve as a source of F. hepatica infection for definitive hosts.

https://doi.org/10.1590/s1984-296120180024 1297 downloads

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