RESUMO: O objetivo deste estudo retrospectivo foi avaliar o impacto da apresentação clínica da piometra na morbimortalidade das cadelas afetadas. Foram avaliados os registros clínicos de 47 cadelas tratadas cirurgicamente para piometra entre maio e dezembro de 2017. Os dados recolhidos na admissão foram analisados para classificar os animais quanto à apresentação clínica da piometra, presença de critérios da Síndrome da Resposta Inflamatória Sistêmica (SRIS) e disfunções orgânicas - cardiovascular, neurológica, renal e hemostática. Foi registrado o desfecho durante 14 dias. A mortalidade global foi de 13%. Piometra aberta e fechada foram identificadas em 62% (n= 29) e 38% (n= 18) respectivamente. SRIS esteve presente em 44 (94%) cadelas e 27 (57%) tiveram pelo menos uma disfunção orgânica. A disfunção mais prevalente foi a hemostática, seguida da neurológica, cardiovascular e renal. A apresentação clínica da piometra e a presença de SRIS não se correlacionaram entre si ou com presença de disfunção orgânica e mortalidade. No entanto, a quantidade de disfunções orgânicas (r=0.532, P=<0.001) e a presença das disfunções neurológica (r= -0.371; P=0.012) e renal (r=0.303; P=0.041) foram correlacionados com mortalidade. Assim, a identificação de disfunções orgânicas através do exame físico e análises laboratoriais de rotina mostrou-se mais eficaz na identificação e previsão de pacientes críticos do que os critérios de SRIS ou a apresentação clínica da doença. RESUMO afetadas 4 2017 (SRIS hemostática 1 dias 13 13% 62 n= n (n 29 38 18 respectivamente 94% 94 (94% 2 57% 57 (57% entanto r=0.532, r0532 r 0 532 (r=0.532 P=<0.001 P0001 P 001 r= (r 0.371 0371 371 -0.371 P=0.012 P0012 012 r=0.303 r0303 303 (r=0.303 P=0.041 P0041 041 Assim mostrouse mostrou doença 201 6 3 9 (94 5 (57 r=0.532 r053 53 (r=0.53 P=<0.00 P000 00 0.37 037 37 -0.37 P=0.01 P001 01 r=0.30 r030 30 (r=0.30 P=0.04 P004 04 20 (9 (5 r=0.53 r05 (r=0.5 P=<0.0 P00 0.3 03 -0.3 P=0.0 r=0.3 r03 (r=0.3 ( r=0.5 r0 (r=0. P=<0. P0 0. -0. P=0. r=0. (r=0 P=<0 -0 P=0 r=0 P=< P=

ABSTRACT: This retrospective study evaluated the impact of the clinical presentation of pyometra on the morbidity and mortality of the affected bitches. The medical records of 47 bitches surgically treated for pyometra between May and December 2017 were evaluated. The admission data were analyzed to classify the animals according to the clinical presentation of pyometra, presence of systemic inflammatory response syndrome (SIRS) and organic dysfunctions (cardiovascular, neurological, renal, and hemostatic). The outcomes were recorded for up to 14 days. The overall mortality rate was 13%. Open and closed pyometra were identified in 62% (n= 29) and 38% (n= 18) of the cases, respectively. The SIRS was present in 44 (94%) bitches, and 27 (57%) had at least one organ dysfunction. The most prevalent dysfunction was hemostatic, followed by neurological, cardiovascular, and renal dysfunction. The clinical presentation of pyometra and the presence of SIRS did not correlate with each other, or with the presence of organ dysfunction and mortality. However, cumulative organ dysfunction (r=0.532, P=<0.001) and the presence of neurological (r= -0.371; P=0.012) and renal dysfunction (r=0.303; P=0.041) were correlated with mortality. Thus, the identification of organ dysfunction through physical examination and routine laboratory analysis proved to be more effective in identifying and predicting the critically ill patients than the SIRS criteria or clinical presentation of the disease. ABSTRACT 4 201 (SIRS cardiovascular (cardiovascular hemostatic. hemostatic . hemostatic) 1 days 13 13% 62 n= n (n 29 38 18 cases respectively 94% 94 (94% 2 57% 57 (57% other However r=0.532, r0532 r 0 532 (r=0.532 P=<0.001 P0001 P 001 r= (r 0.371 0371 371 -0.371 P=0.012 P0012 012 r=0.303 r0303 303 (r=0.303 P=0.041 P0041 041 Thus disease 20 6 3 9 (94 5 (57 r=0.532 r053 53 (r=0.53 P=<0.00 P000 00 0.37 037 37 -0.37 P=0.01 P001 01 r=0.30 r030 30 (r=0.30 P=0.04 P004 04 (9 (5 r=0.53 r05 (r=0.5 P=<0.0 P00 0.3 03 -0.3 P=0.0 r=0.3 r03 (r=0.3 ( r=0.5 r0 (r=0. P=<0. P0 0. -0. P=0. r=0. (r=0 P=<0 -0 P=0 r=0 P=< - P=

RESUMEN Introducción: Eventos como los Juegos Paralímpicos dejan una serie de legados en las sociedades anfitrionas. Esto también es aplicable al desarrollo de conocimiento científico asociado, especialmente en el campo de la biomecánica deportiva. Objetivo: El objetivo de este estudio es investigar la producción científica brasileña en el campo de la biomecánica en deportes paralímpicos durante el ciclo que precedió y siguió a los Juegos Paralímpicos de Río 2016. Además, el estudio tiene como propósito brindar ideas para futuros esfuerzos de investigación. Métodos: La búsqueda se realizó en la Plataforma Lattes, utilizando los filtros “ Assunto “ y “Doutores” y las palabras clave “Paralímpico” y “Paralympic”. En total, se identificaron 723 autores que publicaron artículos relacionados con el tema. Posteriormente, se accedió a los currículos y se clasificaron e identificaron los artículos, lo que resultó en 37 artículos que cumplieron con todos los criterios de inclusión. Resultados: Los resultados indican que: a) Brasil experimentó un aumento en el número de publicaciones después de Londres 2012; b) La mayoría de estas producciones (87%) provienen de Instituciones Públicas; c) Después de Río 2016, hubo una mayor participación de otras regiones de Brasil en la producción de conocimiento en el área; d) Las modalidades individuales, como levantamiento de pesas y atletismo, fueron las más investigadas, a pesar del estatus de referencia de Brasil en algunas modalidades colectivas; e) Las mujeres siguen siendo una minoría, tanto como participantes en investigaciones como autoras de publicaciones; f) Las producciones demuestran altos niveles de calidad; g) Las técnicas de investigación más utilizadas en biomecánica fueron la cinemática y la dinamometría. Conclusión: El campo de la biomecánica en deportes paralímpicos ha sido significativamente beneficiado por el legado generado por los Juegos Paralímpicos de Río 2016. Como desafíos futuros para los investigadores, se destacan los siguientes aspectos: mantener la calidad de las producciones, ampliar los estudios para incluir modalidades colectivas, aumentar la participación de otras entidades federadas en la producción del conocimiento en este campo, promover una mayor equidad de género e incorporar nuevas técnicas de investigación en biomecánica. Nivel de Evidencia II; Estudio de Revisión. Introducción anfitrionas asociado deportiva Objetivo 2016 Además Métodos Lattes Doutores “Doutores Paralímpico “Paralímpico Paralympic. Paralympic . “Paralympic” total 72 tema Posteriormente 3 inclusión Resultados 2012 b 87% 87 (87% Públicas c área d individuales atletismo investigadas colectivas minoría f g dinamometría Conclusión investigadores aspectos II Revisión 201 “Paralympic 7 8 (87 20 (8 2 (

ABSTRACT Introduction: Events such as the Paralympic Games leave a series of legacies in the host societies. This is also applicable to the development of associated scientific knowledge, particularly in the field of sports biomechanics. Objective: The objective of this study is to investigate the Brazilian scientific production in the field of biomechanics in Paralympic sports during the cycle that preceded and followed the Rio 2016 Paralympic Games. Additionally, the study aims to provide insights for future research endeavors. Methods: The search was conducted on the Lattes Platform, utilizing the filters “Assunto” and “Doutores” and the keywords “Paralímpico” and “Paralympic.” In total, 723 authors were identified who published articles related to the topic. Subsequently, the curricula were accessed, and the articles were sorted and identified, resulting in 37 articles that met all inclusion criteria. Results: The results indicate that: a) Brazil witnessed an increase in the number of publications after London 2012; b) The majority of these productions (87%) originate from Public Institutions; c) There was a greater participation of other regions of Brazil in the production of knowledge in the area after Rio 2016; d) Individual modalities such as powerlifting and athletics were the most researched, despite Brazil's reference status in some collective modalities; e) Women remain a minority, both as participants in research and as authors of publications; f) The productions demonstrate high levels of quality; g) The most commonly used research techniques in biomechanics were kinematics and dynamometry. Conclusion: The field of biomechanics in Paralympic sports has significantly benefited from the legacy generated by the Rio 2016 Paralympics. As future challenges for researchers, the following aspects stand out: maintaining the quality of productions, expanding studies to include collective modalities, increasing the participation of other federated entities in the production of knowledge in this field, promoting greater gender equity, and incorporating new research techniques in biomechanics. Level of Evidence II; Review Study. Introduction societies Objective 201 Additionally endeavors Methods Platform Assunto “Assunto Doutores “Doutores Paralímpico “Paralímpico Paralympic. “Paralympic. total 72 topic Subsequently accessed 3 criteria Results 2012 b 87% 87 (87% Institutions c d researched Brazils s e minority f g dynamometry Conclusion Paralympics researchers out equity II Study 20 “Paralympic 7 8 (87 2 (8 (

RESUMO Introdução: Eventos como os Jogos Paralímpicos deixam uma série de legados nas sociedades que as sediam. Não seria diferente quando se trata do desenvolvimento do conhecimento científico associado, em especial a biomecânica do esporte. Objetivo: Investigar a produção científica brasileira produzida em biomecânica no esporte paralímpico no ciclo que antecedeu e sucedeu os Jogos Paralímpicos Rio 2016, além de fornecer insights para novos estudos. Métodos: Foram realizadas buscas na Plataforma Lattes, sendo habilitados os filtros “Assunto” e “Doutores”, com as palavras-chave “Paralímpico” e “Paralympic”. Ao todo, foram encontrados 723 autores que publicaram artigo(s) relacionado(s) com o tema. Após acessar os currículos, os artigos foram triados e identificados, resultando em 37 artigos que preencheram todos os critérios de inclusão. Resultados: Os resultados mostram que a) Após Londres-2012, o Brasil tem aumentado o número de publicações; b) Grande parte das produções (87%) são oriundas de Instituições Públicas, c) Após Rio-2016 houve uma maior participação de outras regiões do Brasil na produção do conhecimento na área, d) Apesar do Brasil ser referência em algumas modalidades coletivas, modalidades individuais como o powerlifting e o atletismo, são as mais pesquisadas, e) Mulheres ainda são minoria, tanto como participantes das pesquisas quanto na autoria das publicações, f) As produções atingem elevados extratos de qualidade, g) As técnicas de pesquisa em biomecânica mais utilizadas foram a cinemática e dinamometria. Conclusão: A biomecânica no esporte paralímpico tem se valido do legado gerado pelas paralimpíadas Rio-2016. Como desafios futuros para os pesquisadores, destacam-se: manutenção da qualidade das produções, ampliação dos estudos para as modalidades coletivas, aumento da participação de outros entes federados na produção do conhecimento na área, promoção de uma maior equidade de gênero e incorporação de novas técnicas de pesquisa em biomecânica. Nível de Evidência II; Estudo de Revisão. Introdução sediam associado Objetivo 2016 Métodos Lattes Assunto “Assunto Doutores, Doutores , “Doutores” palavraschave palavras chave Paralímpico “Paralímpico Paralympic. Paralympic . “Paralympic” todo 72 artigo s artigo(s relacionados relacionado relacionado(s tema currículos identificados 3 inclusão Resultados Londres2012, Londres2012 Londres 2012, 2012 Londres-2012 publicações b 87% 87 (87% Públicas c Rio2016 Rio-201 área d coletivas atletismo pesquisadas minoria f g dinamometria Conclusão Rio2016. 2016. pesquisadores destacamse destacam destacam-se II Revisão 201 “Doutores “Paralympic 7 Londres201 Londres-201 8 (87 Rio201 Rio-20 20 Londres20 Londres-20 (8 Rio20 Rio-2 2 Londres2 Londres-2 ( Rio2 Rio- Londres-

Abstract This article aims to evaluate the effect of the COVID-19 pandemic on malnutrition among children under two years of age enrolled in the Bolsa Família Program (BFP). Ecological study of interrupted time series (ITS), with low weight for age, stunting, and overweight as time-dependent variables of malnutrition, extracted monthly (Jan/2008 to June/2021) from the Food and Nutrition Surveillance System. The COVID-19 pandemic was the exposure, dichotomized into pre-pandemic and pandemic. In RStudio, the trend was obtained by Prais-Winsten regression, and the effect of the pandemic on the time-dependent variables was determined by SARIMA modeling, estimating the regression coefficients (RC) adjusted for trend and seasonality (α = 5%). The pandemic was associated with an increase in: i) low weight for age in the South (RC = 0.94; p < 0.001) and Southeast (RC = 1.97; p < 0.001); ii) height deficit in the Midwest (RC = 2.4; p = 0.01), South (RC = 2.15; p < 0.001) and Southeast (RC = 2.96; p < 0.001); and iii) and overweight in the North (RC = 1.51; p = 0.04), Midwest (RC = 2.29; p = 0.01), South (RC = 2.83; p < 0.001), and Southeast (RC = 0.72; p = 0.04). The pandemic increased underweight in the South and Southeast, and the double burden of malnutrition in the Midwest, South, and Southeast. In the Northeast and North, higher rates of malnutrition still persist.

Resumo O objetivo do artigo é avaliar o efeito da pandemia de COVID-19 sobre a má nutrição em crianças menores de dois anos inscritas no Programa Bolsa Família. Estudo ecológico de série temporal interrompida, tendo o baixo peso por idade, o déficit de estatura e o excesso de peso como variáveis tempo-dependentes de má nutrição, extraídas mensalmente (jan/2008 a junho/2021) do Sistema de Vigilância Alimentar e Nutricional. A pandemia de COVID-19 foi a exposição, dicotomizada em pré e pandemia. No programa RStudio, a tendência foi obtida pela regressão de Prais-Winsten, e o efeito da pandemia sobre as variáveis tempo-dependentes, pela modelagem SARIMA, calculando-se coeficientes de regressão (CR) ajustados para tendência prévia e sazonalidade (α = 5%). A pandemia se associou ao aumento do: i) baixo peso por idade no Sul (CR = 0,94; p < 0,001) e Sudeste (CR = 1,97; p < 0,001); ii) déficit de estatura no Centro-Oeste (CR = 2,4; p = 0,01), Sul (CR = 2,15; p < 0,001) e Sudeste (CR = 2,96; p < 0,001); e iii) excesso de peso no Norte (CR = 1,51; p=0,04), Centro-Oeste (CR = 2,29; p = 0,01), Sul (CR = 2,83; p < 0,001) e Sudeste (CR = 0,72; p = 0,04). A pandemia aumentou o baixo peso no Sul e Sudeste e a dupla carga de má nutrição no Centro-Oeste, no Sul e no Sudeste. No Nordeste e no Norte persistem taxas mais altas de má nutrição.

Abstract This study aimed to investigate the biogenic composition of calcium carbonate (CaCO 3) in pelagic sediments in the Santos Basin over the past 140,000 years. The content and composition of CaCO 3 in different sediment fractions were evaluated, including the bulk sample, coarse fraction (foraminifera), medium fraction (juvenile foraminifera and fragments), and fine fraction (nannofossils), to determine the contribution of each fraction to the carbonated sediment composition. We found that variations in CaCO 3 levels were closely linked to glacial and interglacial periods, with higher values during interglacial periods and lower values during glacial periods. The main factor controlling the variation in CaCO 3 was dissolution, which was mainly linked to the influx of more corrosive southern water masses. Fluctuations in CaCO 3 levels were influenced by variations in productivity and dilution caused by terrigenous sediments. Nevertheless, it is noteworthy that both processes held a relatively minor impact compared to dissolution. Productivity primarily contributed to increased dissolution rates. During periods of low sea levels, dilution by terrigenous sediments became significant (similarly, the influence of the La Plata River plume was notable). However, due to the limited presence of riverine supply in the study area, which contributes directly to major dilution influences, fluctuations in terrigenous materials were considered of lesser magnitude than those caused by dissolution. The nannofossils were found to be the largest contributor to the total CaCO 3 composition, as they were the fraction least affected by the dissolution process. Overall, our results provide insights into the factors influencing CaCO 3 accumulation in marine sediments and can be used as a tool to determine changes between climatic cycles over time. 140000 140 000 140,00 years evaluated sample foraminifera, , (foraminifera) juvenile fragments, fragments fragments) nannofossils, (nannofossils) masses Nevertheless rates similarly, similarly (similarly notable. notable . notable) However area influences process Overall time 14000 14 00 140,0 (foraminifera (nannofossils 1400 1 0 140,

Resumo O objetivo do artigo é avaliar o efeito da pandemia de COVID-19 sobre a má nutrição em crianças menores de dois anos inscritas no Programa Bolsa Família. Estudo ecológico de série temporal interrompida, tendo o baixo peso por idade, o déficit de estatura e o excesso de peso como variáveis tempo-dependentes de má nutrição, extraídas mensalmente (jan/2008 a junho/2021) do Sistema de Vigilância Alimentar e Nutricional. A pandemia de COVID-19 foi a exposição, dicotomizada em pré e pandemia. No programa RStudio, a tendência foi obtida pela regressão de Prais-Winsten, e o efeito da pandemia sobre as variáveis tempo-dependentes, pela modelagem SARIMA, calculando-se coeficientes de regressão (CR) ajustados para tendência prévia e sazonalidade (α = 5%). A pandemia se associou ao aumento do: i) baixo peso por idade no Sul (CR = 0,94; p < 0,001) e Sudeste (CR = 1,97; p < 0,001); ii) déficit de estatura no Centro-Oeste (CR = 2,4; p = 0,01), Sul (CR = 2,15; p < 0,001) e Sudeste (CR = 2,96; p < 0,001); e iii) excesso de peso no Norte (CR = 1,51; p=0,04), Centro-Oeste (CR = 2,29; p = 0,01), Sul (CR = 2,83; p < 0,001) e Sudeste (CR = 0,72; p = 0,04). A pandemia aumentou o baixo peso no Sul e Sudeste e a dupla carga de má nutrição no Centro-Oeste, no Sul e no Sudeste. No Nordeste e no Norte persistem taxas mais altas de má nutrição. COVID19 COVID 19 COVID-1 Família interrompida tempodependentes tempo dependentes jan/2008 jan2008 jan 2008 (jan/200 junho/2021 junho2021 junho 2021 Nutricional exposição RStudio PraisWinsten, PraisWinsten Prais Winsten, Winsten Prais-Winsten tempodependentes, dependentes, SARIMA calculandose calculando CR α 5%. 5 5% . 5%) i 0,94 094 0 94 0,001 0001 001 1,97 197 1 97 ii CentroOeste Centro Oeste 2,4 24 2 4 0,01, 0,01 , 01 0,01) 2,15 215 15 2,96 296 96 iii 1,51 151 51 p=0,04, p004 p=0,04 04 p=0,04) 2,29 229 29 2,83 283 83 0,72 072 72 0,04. 004 0,04 0,04) CentroOeste, Oeste, COVID1 COVID- jan/200 jan200 200 (jan/20 junho/202 junho202 202 0,9 09 9 0,00 000 00 1,9 2, 0,0 2,1 21 2,9 1,5 p00 p=0,0 2,2 22 2,8 28 8 0,7 07 7 jan/20 jan20 20 (jan/2 junho/20 junho20 0, 1, p0 p=0, jan/2 jan2 (jan/ junho/2 junho2 p=0 jan/ (jan junho/ p=

Abstract This article aims to evaluate the effect of the COVID-19 pandemic on malnutrition among children under two years of age enrolled in the Bolsa Família Program (BFP). Ecological study of interrupted time series (ITS), with low weight for age, stunting, and overweight as time-dependent variables of malnutrition, extracted monthly (Jan/2008 to June/2021) from the Food and Nutrition Surveillance System. The COVID-19 pandemic was the exposure, dichotomized into pre-pandemic and pandemic. In RStudio, the trend was obtained by Prais-Winsten regression, and the effect of the pandemic on the time-dependent variables was determined by SARIMA modeling, estimating the regression coefficients (RC) adjusted for trend and seasonality (α = 5%). The pandemic was associated with an increase in: i) low weight for age in the South (RC = 0.94; p < 0.001) and Southeast (RC = 1.97; p < 0.001); ii) height deficit in the Midwest (RC = 2.4; p = 0.01), South (RC = 2.15; p < 0.001) and Southeast (RC = 2.96; p < 0.001); and iii) and overweight in the North (RC = 1.51; p = 0.04), Midwest (RC = 2.29; p = 0.01), South (RC = 2.83; p < 0.001), and Southeast (RC = 0.72; p = 0.04). The pandemic increased underweight in the South and Southeast, and the double burden of malnutrition in the Midwest, South, and Southeast. In the Northeast and North, higher rates of malnutrition still persist. COVID19 COVID 19 COVID-1 BFP. BFP . (BFP) ITS, ITS , (ITS) stunting timedependent dependent Jan/2008 Jan2008 Jan 2008 (Jan/200 June/2021 June2021 June 2021 System exposure prepandemic pre RStudio PraisWinsten Prais Winsten modeling RC α 5%. 5 5% 5%) i 0.94 094 0 94 0.001 0001 001 1.97 197 1 97 ii 2.4 24 2 4 0.01, 0.01 01 0.01) 2.15 215 15 2.96 296 96 iii 1.51 151 51 0.04, 004 0.04 04 0.04) 2.29 229 29 2.83 283 83 0.001, 0.72 072 72 0.04. persist COVID1 COVID- (BFP (ITS Jan/200 Jan200 200 (Jan/20 June/202 June202 202 0.9 09 9 0.00 000 00 1.9 2. 0.0 2.1 21 2.9 1.5 2.2 22 2.8 28 8 0.7 07 7 Jan/20 Jan20 20 (Jan/2 June/20 June20 0. 1. Jan/2 Jan2 (Jan/ June/2 June2 Jan/ (Jan June/

Objetivo: mapear o conhecimento científico sobre as atitudes e percepções dos estudantes de enfermagem em relação ao idadismo. Método: revisão de escopo segundo as recomendações do Joanna Briggs Institute . A pergunta de estudo foi: Quais são as evidências científicas disponíveis sobre as atitudes e percepções dos estudantes de enfermagem no que diz respeito ao idadismo? A busca foi realizada em 12 bases de dados utilizando o aplicativo Rayyan e o Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews . Realizou-se a seleção dos estudos por dois revisores, com uso de um instrumento para a extração dos dados. Resultados: dos 4.595 arquivos, selecionaram-se 46 publicados entre 1984 e 2022, sendo que a maioria utilizou o método quantitativo. O instrumento mais utilizado foi o Kogan’s Attitudes Toward Old People Scale e os estudos mostraram que os estudantes apresentaram atitudes e percepções positivas, negativas, mistas, neutras e não conclusivas. Conclusão: as atitudes e percepções sobre idadismo são diversificadas e não conclusivas. Recomenda-se estudos futuros de intervenção para detecção de mudanças de comportamento dos estudantes de enfermagem frente ao idadismo. Objetivo Método 1 MetaAnalyses Meta Analyses Realizouse Realizou se revisores Resultados 4595 4 595 4.59 arquivos selecionaramse selecionaram 198 2022 quantitativo Kogans Kogan s positivas negativas mistas conclusivas Conclusão Recomendase Recomenda 459 59 4.5 19 202 45 5 4. 20 2

Objective: to map scientific knowledge on nursing students’ attitudes and perceptions regarding ageism. Method: scoping review according to the recommendations of the Joanna Briggs Institute. The study question was: What are scientific evidence available on the attitudes and perceptions of nursing students regarding ageism? The search was conducted in 12 databases using the Rayyan application and the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews. The studies were selected by two reviewers using a data extraction tool. Results: of the 4,595 files, 46 that were published between 1984 and 2022 were selected, and the quantitative method was the most used. The most commonly used instrument was the Kogan’s Attitudes Toward Old People Scale. Positive, negative, mixed, neutral, and inconclusive attitudes and perceptions were identified. Conclusion: attitudes and perceptions about ageism are diverse and not conclusive. Future intervention studies are recommended to detect changes in the behavior of nursing students in the face of ageism. Objective Method Institute 1 MetaAnalyses Meta Analyses Reviews tool Results 4595 4 595 4,59 files 198 202 Kogans Kogan s Scale Positive negative mixed neutral identified Conclusion conclusive 459 59 4,5 19 20 45 5 4, 2

Objetivo: mapear el conocimiento científico sobre las actitudes y percepciones de los estudiantes de enfermería respecto al edadismo. Método: La pregunta del estudio fue: ¿Qué evidencia científica está disponible sobre las actitudes y percepciones de los estudiantes de enfermería respecto al edadismo? La búsqueda se realizó en 12 bases de datos utilizando la aplicación Rayyan y la Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews . Los estudios fueron seleccionados por dos revisores mediante una herramienta de extracción de datos. Resultados: de los 4.595 artículos, se seleccionaron 46 publicados entre 1984 y 2022, siendo el método cuantitativo el más utilizado. La herramienta más utilizada fue el Kogan’s Attitudes Toward Old People Scale . Se identificaron actitudes y percepciones positivas, negativas, mixtas, neutras y no concluyentes. Conclusión: las actitudes y percepciones sobre la discriminación por edad son diversas y no concluyentes. Se recomiendan futuros estudios de intervención para detectar cambios en el comportamiento de los estudiantes de enfermería ante el edadismo. Objetivo edadismo Método Qué 1 MetaAnalyses Meta Analyses Resultados 4595 4 595 4.59 artículos 198 2022 utilizado Kogans Kogan s positivas negativas mixtas concluyentes Conclusión 459 59 4.5 19 202 45 5 4. 20 2

Resumo O vazamento sonoro dos camarotes do Sambódromo do Rio de Janeiro para a avenida dos desfiles durante o carnaval de 2022 foi amplamente comentado nos circuitos de samba e na imprensa. Este texto discute os múltiplos atravessamentos gerados pela tensão sonora durante o evento, entendendo que o conflito derivado da disputa musical dramatiza diversas tensões sociais bastante recorrentes nos desfiles do carnaval carioca, relacionados a questões de classe e raça. O carnaval é uma festa popular que negocia desde sempre espaços físicos na cidade, numa tensão que também encarna disputas por espaços simbólicos. O som dos camarotes atravessado com as baterias das escolas de samba pode ser pensado como outra camada de disputas por espaços sonoros, numa complexa engrenagem que reverbera modos de pensar e negociar as hierarquias sociais. 202 imprensa evento carioca raça cidade simbólicos sonoros 20 2

Abstract The sound leakage from the Rio de Janeiro’s Sambódromo’s VIP boxes onto the parade avenue during the 2022 carnival was widely commented on in the samba circuits and the press. This text discusses the multiple discourses generated by the sound tension during the event, understanding these conflicts as a musical dispute which dramatizes several of the recurrent social tensions in Rio’s carnival in their relations to class and race. Carnival is a popular celebration that has always negotiated physical spaces in the city, which also embodies disputes over symbolic spaces. The sound of the VIP boxes crossed with the drums of the samba schools can be thought of as another layer of disputes for sound spaces, in a complex gear that reverberates ways of thinking and negotiating social hierarchies. Janeiros Janeiro s Sambódromos Sambódromo 202 press event Rios race city hierarchies 20 2

RESUMO JUSTIFICATIVA E OBJETIVOS: A incerteza quanto ao momento exato da morte exige previsões de sobrevivência precisas para melhorar o cuidado no final da vida. Este estudo visou mapear e orientar o uso de ferramentas prognósticas em cuidados paliativos (CP), apesar da falta de comparações abrangentes. O objetivo deste estudo foi identificar as evidências disponíveis sobre as Escalas Prognósticas de Sobrevida validadas utilizadas em pacientes em CP. CONTEÚDO: Foi realizada uma revisão de escopo utilizando o método do Instituto Joanna Briggs, com a metodologia PCC (população, conceito e contexto) nas bases de dados Excerpta Medica Database (EMBASE), Medline (via EMBASE), Cumulative Index to Nursing and Allied Health Literature (CINAHL) Plus with Full Text, Literatura Latino-Americana em Ciências da Saúde (LILACS) e SCOPUS. A revisão cobriu 504 estudos publicados entre 1999 e 2020, dos quais 40 permaneceram após três etapas de seleção. Apresenta-se em 13 diferentes ferramentas encontradas e seus fatores prognósticos em formato de tabela e as caracterizamos uma a uma. A escala Índice Prognóstico Paliativo (PPI) estava presente em 52,5% dos estudos, aparecendo no maior número de publicações. CONCLUSÃO: Esta revisão de escopo revelou um número ainda pequeno de estudos relacionados a ferramentas prognósticas em CP, especialmente abordando outras doenças com risco de vida, o que dificulta a construção de políticas internacionais, assim como demonstra o custo-benefício e a efetividade dessas ferramentas. O grande número de diferentes fatores prognósticos torna cada escala mais indicada e eficaz dependendo do cenário, confirmando a necessidade de pesquisas para avaliar a aplicabilidade e a efetividade destas, não apenas em um, mas em vários ambientes e situações diferentes. OBJETIVOS vida CP , (CP) abrangentes CONTEÚDO Briggs população, população (população contexto EMBASE, EMBASE (EMBASE) via EMBASE) CINAHL (CINAHL Text LatinoAmericana Latino Americana LILACS (LILACS SCOPUS 50 199 2020 4 seleção Apresentase Apresenta se 1 PPI (PPI 525 52 5 52,5 publicações CONCLUSÃO internacionais custobenefício custo benefício cenário destas (CP (EMBASE 19 202 52, 20 2

ABSTRACT BACKGROUND AND OBJECTIVES: The uncertainty of death’s exact timing necessitates accurate survival predictions for better end-of-life care. This study was to map and guide the use of prognostic tools in palliative care (PC), despite the lack of comprehensive comparisons. The objective of this study was to identify the available evidence of the validated Prognostic Survival Scales used in patients in PC. CONTENTS: A scope review was performed using the Joanna Briggs Institute method, with PCC methodology (population, concept, and context) in the Excerpta Medica Database (EMBASE), Medline (via EMBASE), Cumulative Index to Nursing and Allied Health Literature (CINAHL) Plus with Full Text, Latin American Literature in Health Sciences (LILACS) and SCO-PUS. The review covered 504 studies published between 1999 and 2020, of which 40 remained after three selection stages. The study presents 13 different tools found and their prognostic factors in table form and characterize them one by one. The PPI (Palliative Prognostic Index) scale was present in 52.5% of the studies, appearing in the highest number of publications. CONCLUSION: This scope review shows a still small number of studies related to prognostic tools in PC, in particular, addressing other life-threatening diseases, making it difficult to build international policies, as well as demonstrating their cost-benefit and effectiveness. The large number of different prognostic factors makes each scale more indicated and effective depending on the scenario, confirming the need for research to evaluate the applicability and effectiveness of these, not only in one, but in several different environments and situations. OBJECTIVES deaths death s endoflife end life PC , (PC) comparisons CONTENTS method population, population (population concept context EMBASE, EMBASE (EMBASE) via EMBASE) CINAHL (CINAHL Text LILACS (LILACS SCOPUS. SCOPUS SCO PUS. PUS SCO-PUS 50 199 2020 4 stages 1 Palliative 525 52 5 52.5 publications CONCLUSION particular lifethreatening threatening diseases policies costbenefit cost benefit scenario these situations (PC (EMBASE 19 202 52. 20 2

ABSTRACT. The objective of this study was to identify the genetic, phenotypic and environmental parameters related to chemical compounds associated with beverage quality in a conilon coffee collection, grown in an irrigated system, in the Cerrado. The experiment was carried out at Embrapa Cerrados using green grains harvested in two years from 84 genotypes of the cultivar Robusta Tropical. Caffeine content, protein, ether extract, total soluble solids, pH and titratable acidity were evaluated. The data were subjected to analysis of variance. Significant differences were observed at 1% probability among accessions for all evaluated chemical characteristics in both harvest years. The high heritability, genetic coefficients of variation and selective accuracy reveal the potential for achieving genetic gains via the selection of genotypes adapted to the irrigated system in the Cerrado combined with high beverage quality. ABSTRACT collection 8 Tropical content protein extract solids variance 1 heritability

Abstract Background: Atrial fibrillation (AF) stands out as the most prevalent arrhythmia, and its incidence increases with age. Stroke ranks as the second leading cause of mortality in Brazil and represents the primary contributor to global disability. Objective: Considering the severity of these conditions, this study seeks to elucidate the epidemiological landscape of AF and stroke-related deaths in Brazil from 1996 to 2022. Methods: The following variable were analyzed in the study - geographic region, federative state, age demographics, gender distribution, year of mortality, race/ethnicity, educational attainment, and place of death. This research adopted a descriptive approach through a retrospective, exploratory, epidemiological analysis of data sourced from the Mortality Information System (SIM) accessible through the Department of Health Informatics of the Brazilian Unified Health System (DATASUS) website. Results: Over the 26-year period, 1,201,327 deaths from AF and stroke were registered in Brazil. These deaths were mostly caused by stroke (94.5%) and were more concentrated in the southeast region, where the highest number of doctors capable of identifying and notifying these deaths are also concentrated. Conclusion: This study claims for a paradigm shift in disease control strategies and underscores the imperative of bolstering the efficacy of public health policies to address the huge impact of stroke and AF-related mortality on population health. Background (AF arrhythmia disability Objective conditions strokerelated related 199 2022 Methods region state demographics distribution raceethnicity race ethnicity race/ethnicity attainment death retrospective exploratory SIM (SIM DATASUS (DATASUS website Results 26year 26 period 1201327 1 201 327 1,201,32 94.5% 945 94 5 (94.5% Conclusion AFrelated 19 202 2 120132 20 32 1,201,3 94.5 9 (94.5 12013 3 1,201, 94. (94. 1201 1,201 (94 120 1,20 (9 12 1,2 ( 1,

Resumo A grande biodiversidade das espécies de peixes neotropicais que possuem a fertilização externa como estratégia reprodutiva, a exemplo do tambaqui, exige análises mais criteriosas em testes toxicológicos dos diversos defensivos agrícolas implementados na agricultura brasileira ao longo dos últimos anos. Nesse contexto, o objetivo do presente trabalho foi avaliar possíveis alterações espermáticas no sêmen de tambaqui (Colossoma macropomum) exposto a resíduos de dois diferentes pesticidas. Foram utilizadas amostras seminais de machos de tambaqui sexualmente maduros provenientes de uma piscicultura local. O sêmen foi coletado oito horas pós indução hormonal em tubos de vidro graduados. Após avaliação inicial de inexistência de ativação prévia, foi realizado o experimento em esquema fatorial, sendo testados dois pesticidas muito utilizados em sistemas agrícolas (glifosato e fenitrotiona). Para cada pesticida foram testadas cinco concentrações (6, 12, 24, 120 e 240 mg/L), com análise da motilidade nos tempos 0, 30 e 60 segundos pós ativação. Como controle, foi utilizada a ativação com solução de NaCl a 0,9% e análise da motilidade nos mesmos tempos descritos para os pesticidas. Resultados indicam que as amostras in natura exibiram motilidade inicial de 89,2 ± 4,9% e tempo de duração médio de 100 segundos (até 10% de motilidade espermática). A redução da motilidade espermática ocorreu de forma significativa (p < 0,05) após 30 segundos em todas as concentrações testadas, exceto na concentração de 240 mg/L por não ter sido observada ativação. Os testes aqui descritos demonstram que o sêmen de tambaqui se mostrou sensível ao processo de exposição aos resíduos de pesticidas, podendo ser utilizado em análises de biomonitoramento dos referidos defensivos agrícolas. reprodutiva anos contexto Colossoma macropomum local graduados prévia fatorial glifosato fenitrotiona. fenitrotiona . fenitrotiona) 6, 6 (6 12 24 mg/L, mgL , mg L mg/L) 0 3 controle 09 9 0,9 892 89 2 89, 49 4 4,9 10 até espermática. espermática) p 0,05 005 05 ( 1 8 4, 0,0 00

Abstract The great biodiversity of neotropical fish species that have external fertilization as a reproductive strategy, like the tambaqui, requires more careful analyzes in toxicological tests of the various pesticides implemented in Brazilian agriculture over the last few years. In this context, the objective of the present work was to evaluate possible sperm alterations in tambaqui (Colossoma macropomum) semen exposed to two different pesticide residues. Seminal samples of sexually mature tambaqui males from a local fish farm were used. Semen was collected eight hours after hormone induction into graduated glass tubes. After initial assessment of the lack of prior activation, the experiment was carried out in a factorial scheme, testing two pesticides widely used in agricultural systems (glyphosate and fenitrothion). For each pesticide, five concentrations were tested (6, 12, 24, 120 and 240 mg/L), with motility analysis at times 0, 30 and 60 seconds after activation. As a control, activation with 0.9% NaCl solution and motility analysis at the same times described for pesticides were used. Results indicate that in natura samples exhibited initial motility of 89.2 ± 4.9% and mean duration of 100 seconds (up to 10% sperm motility). The reduction in sperm motility occurred significantly (p < 0.05) after 30 seconds in all concentrations tested, except for the concentration of 240 mg/L because no activation was observed. The tests described here demonstrate that tambaqui semen was sensitive to the process of exposure to pesticide residues, and can be used in biomonitoring analyzes of the aforementioned agricultural pesticides. strategy years context Colossoma macropomum residues tubes scheme glyphosate fenitrothion. fenitrothion . fenitrothion) 6, 6 (6 12 24 mg/L, mgL , mg L mg/L) 0 3 control 09 9 0.9 892 89 2 89. 49 4 4.9 10 up motility. motility) p 0.05 005 05 observed ( 1 0. 8 4. 0.0 00

ABSTRACT Objective To analyze the karyotype test and myeloid panel with next-generation sequencing findings in patients with myelofibrosis, and to compare transplant characteristics in patients referred for bone marrow transplantation. Methods Retrospective, single-center study with patients diagnosed with myelofibrosis treated at Hospital Israelita Albert Einstein between 2010 and 2020. Results A total of 104 patients with myelofibrosis were examined. Patients who had not been submitted to tests in our service were excluded. The final sample comprised 69 patients. Of these 69, 56 were submitted to karyotyping and 22 to myeloid panel with next-generation sequencing. Karyotype was normal in 60% of the patients and altered in 40%. The prevalence of high-risk molecular mutations was higher in patients referred for bone marrow transplantation (100% versus 50%). The median follow-up of transplant patients was 2.4 years and the overall survival at 2 years was 80% (95%CI: 62-100%). Conclusion The molecular analysis enables estimating the patient’s risk and thus instituting more aggressive treatment such as bone marrow transplant for patients at higher risk, being a relevant tool to guide therapy. Given the significance of molecular analysis for therapeutic decision-making in myelofibrosis, collection and disclosure of data on the prevalence of cytogenetic changes and findings of next-generation sequencing in affected patients is important. nextgeneration next generation Retrospective singlecenter single center 201 2020 10 examined excluded 6 5 60 40 40% highrisk high 100% 100 (100 50%. 50 50% . 50%) followup follow up 24 4 2. 80 95%CI 95CI CI 95 (95%CI 62100%. 62100 62 62-100%) patient s therapy decisionmaking decision making important 20 202 1 (10 8 9 62100% 6210 62-100% (1 621 62-100 ( 62-10 62-1 62-

Abstract Consumers are more demanding in relation to meat quality, developing new demands, such as increased shelf life and good sensory quality. The tenderness of the meat is one of the most important elements in the choice of the product, the modification in the intrinsic structure of the meat, for example, increase of the proteolysis and fragmentation of the myofibrils contribute to the improvement of the tenderness. However, it is necessary to develop technological strategies so that this ultrasound technology can be added to improve meat tenderness. Thus, the objective of this review was to know the main aspects of the use of ultrasound and acerola residue in meat tenderness. Overall, existing research demonstrates excellent prospects for this new redesign approach.

Abstract: Background and Aims: Vanilla is one of the well-known genera of the family Orchidaceae due to the ornamental, medicinal and culinary attributes of some of its taxa. The genus is pantropical and has about 120 species mostly found in the Neotropics. The objective of this study was to report the occurrence of V. karenchristianae in the Brazilian Atlantic Forest. Methods: We present a morphological description of V. karenchristianae based on the analysis of the newly found population in the state of Bahía, Brazil, and the materials collected in other sites of the country and deposited in herbaria. Also, we provide taxonomical and habitat comments, photographs, and a distribution map of V. karenchristianae in Brazil. Key results: The present record represents the most eastern distribution of V. karenchristianae and is approximately 2380 kilometers far from the nearest locality where the species has been recorded. In Brazil, V. karenchristianae is currently known from the Amazon and Atlantic Forest phytogeographic domains and from only four localities, including the one added here. Conclusions: Further recording efforts are necessary to fully understand the geographical distribution and ecological requirements of V. karenchristianae.

Resumen: Antecedentes y Objetivos: Vanilla es uno de los géneros más conocidos de la familia Orchidaceae debido a los atributos ornamentales, medicinales y culinarios de algunos de sus taxones. El género es pantropical y tiene alrededor de 120 especies que se encuentran principalmente en el Neotrópico. El objetivo de este estudio fue informar la ocurrencia de V. karenchristianae en el bosque Atlántico brasileño. Métodos: Presentamos una descripción morfológica de V. karenchristianae con base en el análisis de la población recién encontrada en el estado de Bahía, Brasil, y en los materiales recolectados en otros sitios del país y depositados en herbarios. Además, proporcionamos comentarios taxonómicos y de hábitat, fotografías y un mapa de distribución de V. karenchristianae en Brasil. Resultados clave: El presente registro representa la distribución más oriental de V. karenchristianae y está aproximadamente a 2380 kilómetros de la localidad más cercana donde se ha registrado la especie. En Brasil, V. karenchristianae es actualmente conocida de los dominios fitogeográficos de Amazonía y Mata Atlántica y de solo cuatro localidades, incluida la que se agrega aquí. Conclusiones: Se necesitan más esfuerzos de registro para comprender completamente la distribución geográfica y los requisitos ecológicos de V. karenchristianae.

RESUMO Introdução: Com a pandemia da Covid-19, muitos procedimentos médicos sofreram alterações significativas devido à realocação de recursos para os pacientes contaminados pelo Sars-Cov-2. A logística de transplantes foi diretamente afetada, com repercussões importantes para o paciente na fila de espera para um novo órgão. Objetivo: Esta revisão busca analisar o impacto da pandemia da Covid-19 na logística de disponibilidade de órgãos sólidos e volume de transplantes. Métodos: Foi realizada uma busca integrativa de artigos com os descritores “Covid OR Sars-Cov-2”, “COVID-19”, “Transplant”, “Donor”, “Waiting list”, “Organ donation” no PubMed e Web of Science. Só foram considerados artigos sobre transplante de pâncreas, coração, fígado, rim e intestino, e que abordassem um dos seguintes tópicos: disponibilidade de doadores, volume e tempo na lista de espera, mortalidade dos pacientes em espera, volume de transplantes realizados. Resultados: Dos 68 artigos encontrados, 49 deles eram multicêntricos. Dentre todos os 68, 29 fizeram alguma colocação em relação ao volume de doador, 42 em relação ao volume de transplante, 18 em relação à mortalidade na fila de transplante, 15 em relação ao volume da lista de espera e quatro em relação ao tempo na lista de espera. Com tais dados, de forma geral, foi possível observar diminuição do volume de doadores e do volume de transplantes, redução de adições à lista de espera, e aumento tanto no tempo de espera para transplantes, quanto na mortalidade do paciente que aguardava pelo transplante. Conclusão: A pandemia da SARS-CoV-2 prejudicou diretamente a logística dos transplantes de órgãos sólidos de forma global. Os motivos que levaram a tal fato estão relacionados à diminuição dos leitos de UTI, contaminação do doador pelo vírus, e protocolos rigorosos para prevenção de transmissibilidade do vírus. Introdução Covid19, Covid19 Covid 19, 19 SarsCov2. SarsCov2 SarsCov Sars Cov 2. 2 Sars-Cov-2 afetada órgão Objetivo Covid-1 Métodos SarsCov2, , Sars-Cov-2” COVID19, COVID19 COVID “COVID-19” Transplant, Transplant “Transplant” Donor, Donor “Donor” Waiting list, list list” Organ donation Science pâncreas coração fígado intestino tópicos realizados Resultados 6 encontrados 4 multicêntricos 1 dados geral Conclusão SARSCoV2 SARSCoV SARS CoV SARS-CoV- global UTI vírus Covid1 Sars-Cov- Covid- COVID1 “COVID-19 “Transplant “Donor SARS-CoV Sars-Cov “COVID-1 “COVID- “COVID

ABSTRACT Introduction: With the Covid-19 pandemic, many medical procedures underwent significant changes due to the reallocation of resources to patients infected with Sars-Cov-2. The logistics of transplants were directly affected, with important repercussions for the patient on the waiting list for a new organ. Objective: This review seeks to analyze the impact of the Covid-19 pandemic on the logistics of solid organ availability and volume of transplants. Methods: An integrative search of articles with the descriptors “Covid OR Sars-Cov-2”, “COVID-19”, “Transplant”, “Donor”, “Waiting list”, and “Organ donation” in PubMed and Web of Science was performed. Only articles on pancreas, heart, liver, kidney and intestine transplantation that addressed one of the following topics were considered: availability of donors, volume and time on the waiting list, mortality of patients on the waiting list, and volume of transplants performed. Results: Of the 68 articles found, 49 of them were multicentric. Among all 68, 29 made a statement concerning donor volume, 42 concerning transplant volume, 18 about mortality on the transplant waiting list, 15 concerning the volume on the waiting list, and 4 regarding time on the waiting list. Thus, with such data, in general, it was possible to observe a decrease in the volume of donors and the volume of transplants, besides a reduction in addition to the waiting list and an increase both in the waiting time for transplantation and in the mortality of the patients waiting for the transplant. Conclusion: The SARS-CoV-2 pandemic has directly influenced the logistics of solid organ transplants globally. The reasons that led to this fact are related to the decrease in the availability of ICU beds, contamination of the donor by the virus, and strict protocols to prevent the transmission of the virus. Introduction Covid19 Covid 19 Covid-1 SarsCov2. SarsCov2 SarsCov Sars Cov 2. 2 Sars-Cov-2 affected Objective Methods SarsCov2, , Sars-Cov-2” COVID19, COVID19 COVID “COVID-19” Transplant, Transplant “Transplant” Donor, Donor “Donor” Waiting list” Organ donation performed pancreas heart liver considered Results 6 found multicentric 1 Thus data general Conclusion SARSCoV2 SARSCoV SARS CoV SARS-CoV- globally beds virus Covid1 Covid- Sars-Cov- COVID1 “COVID-19 “Transplant “Donor SARS-CoV Sars-Cov “COVID-1 “COVID- “COVID