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Resumo O gênero Aplectana inclui espécies de helmintos gastrointestinais comumente encontrados parasitando anfíbios e répteis, mundialmente. No entanto, a maioria das espécies do gênero foi descrita com base apenas em caracteres morfológicos. Durante expedições helmintológicas, foram encontrados nematódeos identificados como A. pella parasitando o anuro hilídeo Osteocephalus cabrerai na mesma localidade da descrição original. Foi fornecida a primeira sequência de nucleotídeos do gene ribossomal 18S rDNA de Aplectana pella e se estabeleceu a posição filogenética da espécie em relação aos representantes de Cosmocercidae. Comparações genéticas entre A. pella e seus congêneres revelaram uma baixa divergência genética. Foi encontrado que as sequências estudadas agrupam com espécies de Cosmocerca, reforçando a hipótese que representantes do gênero Aplectana não formam um grupo monofilético.

Abstract Aplectana comprises species of gastrointestinal helminths commonly found parasitizing amphibians and reptiles worldwide. However, most species of the genus are described based only on morphological traits. During helminthological surveys, we found nematodes identified as Aplectana pella parasitizing the hylid frog Osteocephalus cabrerai from the same locality as the original description. We provided the first nucleotide sequence of ribosomal gene 18S rDNA for Aplectana pella and established the species' phylogenetic position between representatives of Cosmocercidae. A pairwise genetic comparison between A. pella and its congeners revealed a low genetic divergence. We found that our sequences clustered with species of Cosmocerca, reinforcing the hypothesis that representatives of the genus Aplectana do not form a monophyletic group.

https://doi.org/10.1590/s1984-29612025007

Joint statement on evidence-based practices in mechanical ventilation: suggestions from two Brazilian medical societies
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Ferreira, Juliana Carvalho

; Vianna, Arthur Oswaldo de Abreu

; Pinheiro, Bruno Valle

; Maia, Israel Silva

; Baldisserotto, Sérgio Vasconcellos

; Isola, Alexandre Marini

; Cavalcanti, Alexandre Biasi Gama, Ana Maria Casati Nogueira da Rocha, Angelo Roncalli Miranda Oliveira, Antonio Gonçalves de Serpa Neto, Ary Farias, Augusto Manoel de Carvalho Orlando, Bianca Rodrigues Esteves, Bruno da Costa Mazza, Bruno Franco Silveira, Camila de Freitas Martins Soares Carvalho, Carlos Roberto Ribeiro de Toufen Junior, Carlos Barbas, Carmen Silvia Valente Teixeira, Cassiano Silveira, Débora Dutra da Medeiros, Denise Machado Parolo, Edino Costa, Eduardo Leite Vieira Caser, Eliana Bernadete Oliveira, Ellen Pierre de Banholzer, Eric Grieger Carvalho, Erich Vidal Amorim, Fabio Ferreira Saddy, Felipe Gonçalves, Fernanda Alves Ferreira Galas, Filomena Regina Barbosa Gomes Zanatta, Giovanna Carolina Gardini Silva, Gisele Sampaio Westphal, Glauco Adrieno Matos, Gustavo Faissol Janot de Souza, João Claudio Emmerich de Silva Junior, João Manoel Valiatti, Jorge Luis dos Santos Nascimento Junior, José Ribamar do Rocco, Jose Rodolfo Hajjar, Ludhmila Abrahão Forgiarini Junior, Luiz Alberto Malbuisson, Luiz Marcelo Sá Holanda, Marcelo Alcantara Amato, Marcelo Britto Passos Park, Marcelo Oliveira, Marco Antonio da Rosa e Reis, Marco Antonio Soares Tavares, Marcos Soares Souza, Mario Henrique Dutra de Damasceno, Marta Cristina Pauleti Lira-Batista, Marta Maria da Silva Pattacini, Max Morais Assunção, Murillo Santucci Cesar de Oliveira, Neymar Elias de Franzosi, Oellen Stuani Rocco, Patricia Rieken Macedo Caruso, Pedro Silva, Pedro Leme Mendes, Pedro Vitale Duarte, Pericles Almeida Delfino Santa Neto, Renato Fabio Alberto Della Rodrigues, Ricardo Goulart Cordioli, Ricardo Luiz Palazzo, Roberta Fittipaldi Goldwasser, Rosane Pinheiro, Sabrina dos Santos Justino, Sandra Regina Nemer, Sergio Nogueira Oliveira, Vanessa Martins de Silva, Vinicius Zacarias Maldaner da Nedel, Wagner Luis Bellissimo-Rodrigues, Wanessa Teixeira Oliveira Filho, Wilson de

Critical Care Science

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2025, Volume 37 elocation e20250242en

Abstract: En | Text: En | PDF: En

ABSTRACT Mechanical ventilation can be a life-saving intervention, but its implementation requires a multidisciplinary approach, with an understanding of its indications and contraindications due to the potential for complications. The management of mechanical ventilation should be part of the curricula during clinical training; however, trainees and practicing professionals frequently report low confidence in managing mechanical ventilation, often seeking additional sources of knowledge. Review articles, consensus statements and clinical practice guidelines have become important sources of guidance in mechanical ventilation, and although clinical practice guidelines offer rigorously developed recommendations, they take a long time to develop and can address only a limited number of clinical questions. The Associação de Medicina Intensiva Brasileira and the Sociedade Brasileira de Pneumologia e Tisiologia sponsored the development of a joint statement addressing all aspects of mechanical ventilation, which was divided into 38 topics. Seventy-five experts from all regions of Brazil worked in pairs to perform scoping reviews, searching for publications on their specific topic of mechanical ventilation in the last 20 years in the highest impact factor journals in the areas of intensive care, pulmonology, and anesthesiology. Each pair produced suggestions and considerations on their topics, which were presented to the entire group in a plenary session for modification when necessary and approval. The result was a comprehensive document encompassing all aspects of mechanical ventilation to provide guidance at the bedside. In this article, we report the methodology used to produce the document and highlight the most important suggestions and considerations of the document, which has been made available to the public in Portuguese.

https://doi.org/10.62675/2965-2774.20250242-en

Higienizadores da atenção primária à saúde no contexto da pandemia COVID-19: entre a invisibilidade e a essencialidade
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Menezes, Fernanda Veloso Costa

; Lima, Mônica Angelim Gomes de

; Neves, Robson da Fonseca

; Coulon, Alain

; Castellanos, Marcelo Eduardo Pfeiffer

Ciência & Saúde Coletiva

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2025, Volume 30 N. 2 elocation e09092023

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo O artigo apresenta a trajetória dos higienizadores da atenção primária à saúde (APS) no contexto da pandemia COVID-19, seus desafios e enfrentamentos. Parte-se da pergunta: como os trabalhadores da higienização expressaram os sentidos de sua experiência sobre o trabalho como higienizador no cenário pandêmico? O objetivo do estudo foi analisar a experiência dos trabalhadores da higienização no trabalho como higienizador durante a pandemia de COVID-19. Adotou-se uma abordagem qualitativa, apoiada na fenomenologia do cotidiano e na etnometodologia, para explorar o trabalho desses atores no contexto da APS. A pesquisa foi desenvolvida em três distritos sanitários (DS) do município de Salvador, Bahia, e em cada DS foram selecionadas duas Unidades de Saúde da Família (USF). A produção dos dados se deu por meio de entrevistas semiestruturadas em profundidade, tanto remotas quanto presenciais. Os resultados revelaram a presença do binômio invisibilidade versus essencialidade no cotidiano dos trabalhadores da higienização na APS, ou seja, ainda que considerados essenciais, não conseguem a visibilidade e o reconhecimento profissional e social.

Abstract This article presents the trajectory of primary health care (PHC) sanitation staff in the context of the COVID-19 pandemic, with the inherent challenges and difficulties involved. It starts with the question: how did hygiene workers express the meanings of their experience of working as hygienists in the pandemic scenario? The objective of this study was to analyze the experience of sanitation workers regarding working as hygienists during the COVID-19 pandemic. A qualitative approach was adopted, based on the phenomenology of everyday life and ethnomethodology, to explore the work of these agents in the PHC context. The research was conducted in three Health Districts (HD) in the city of Salvador - Bahia, where two Family Health Units (FHU) were selected in each HD. The data was collected through in-depth semi-structured interviews, both remote and in-person. The results revealed the existence of the binomial of invisibility versus essentiality in the daily lives of hygiene workers in PHC, in other words even though they are considered essential, they do not achieve visibility and professional and social recognition.

Resumen Este artículo presenta la trayectoria de los desinfectantes en atención primaria de salud (APS) en el contexto de la pandemia de COVID-19, sus desafíos y enfrentamientos. Partiendo de la pregunta: ¿cómo expresaron los trabajadores sanitarios los significados de su experiencia de trabajo como sanitizador en el escenario de pandemia? El objetivo de este estudio fue analizar la experiencia de trabajadores sanitarios sobre su labor como sanitizador durante la pandemia de COVID-19. Se adoptó un enfoque cualitativo, apoyado en la fenomenología y la etnometodología cotidianas, para explorar el trabajo de estos actores en el contexto de la APS. La investigación se desarrolló en tres Distritos de Salud (DS) de la ciudad de Salvador - Bahía y en cada DS se seleccionaron dos Unidades de Salud de la Familia (USF). La producción de datos se realizó a través de entrevistas semiestructuradas en profundidad, tanto remotas como presenciales. Los resultados revelaron la presencia del binomio invisibilidad versus esencialidad en el cotidiano de los trabajadores de higiene en la APS, es decir, aunque considerados esenciales, no alcanzan visibilidad y reconocimiento profesional y social.

https://doi.org/10.1590/1413-81232025302.09092023

Mango (Mangifera indica) meal can partially replace corn meal in diets for piava (Megaleporinus obtusidens) Mangifera indica Megaleporinus obtusidens
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Marchão, Rafael Silva

; Copatti, Carlos Eduardo

; Rocha, Aline da Silva

; Costa, Thaisa Sales

; Silva, Rafael Carvalho da

; Pereira, Gilmar Amaro

; Rocha, David Ramos da

; Melo, José Fernando Bibiano

Ciência Rural

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2025, Volume 55 N. 4 elocation e20230670

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: A produção de manga (Mangifera indica) está se expandindo em muitos países e seus resíduos tem o potencial de ser usado para a fabricação de dietas para peixes. Este estudo avaliou a substituição parcial de fubá de milho por farinha de manga (FM) em dietas para piava (Megaleporinus obtusidens) em termos de performance zootécnica, glicose do plasma, enzimas intestinais e análise microbiológica. Piavas (n = 160) foram distribuídas em um esquema completamente randomizado (quatro tratamentos e quatro repetições) e alimentadas por 45 dias com dietas contendo diferentes níveis de inclusão de FM (0, 33, 66 e 100%). Não houve nenhuma contaminação microbiológica (bolor, coliformes totais, Bacillus cereus e Salmonella sp.) na FM. Os fenóis totais e taninos totais foram maiores na dieta com FM (P < 0.05). Dietas com 100% de fubá de milho substituído por MM reduziu a performance de crescimento e aumento a taxa de conversão alimentar (TCA) e os níveis de glicose nos peixes (P < 0.05). De acordo com a análise de regressão de segunda ordem, o nível ideal de inclusão de FM na dieta estimado com base no ganho de peso e o TCA foi de 23,68 e 19,75%, respectivamente (P < 0.05). O aumento gradual dos níveis de FM substituindo fubá de milho na dieta reduziu a atividade das enzimas intestinais amilase, lipase e protease alcalina (P < 0.05). Em conclusão, recomendamos a substituição de 19,75-23,68% de fubá de milho por FM, que pode ser usada nas dietas de piava. RESUMO Mangifera indica (FM Megaleporinus obtusidens zootécnica plasma n 160 repetições 4 0, 0 (0 33 6 100%. 100 . 100%) bolor, bolor (bolor sp. sp P 0.05. 005 0.05 05 0.05) (TCA ordem 2368 23 68 23,6 1975 19 75 19,75% amilase conclusão 19,7523,68% 19752368 19,75 23,68% 19,75-23,68 16 ( 3 10 00 0.0 236 2 23, 197 1 7 7523 19,7523,68 1975236 19,7 19,75-23,6 0. 752 19,7523,6 197523 19, 19,75-23, 19,7523, 19752 19,75-23 19,7523 19,75-2 19,752 19,75-

ABSTRACT: Mango (Mangifera indica) production is expanding in many countries, and its discarded residues have the potential to be used in the manufacture of fish diets. This study evaluated replacing part of the corn meal (CM) with mango meal (MM) in diets for piava (Megaleporinus obtusidens) in terms of zootechnical performance, plasma glucose, and intestinal enzymes. Piavas (n = 160) were distributed in a completely randomized design (four treatments and four replications) and were fed for 45 days with diets containing different levels of MM inclusion (0, 33, 66, and 100%). There was no microbiological contamination (mold, total coliforms, Bacillus cereus, and Salmonellasp.) in MM. The MM diet had higher total phenols and total tannins (P < 0.05). Diets with 100% of the CM replaced by MM reduced the growth performance and increased the feed conversion ratio (FCR) and plasma glucose levels in piava (P < 0.05). According to the second-order regression analysis, the optimal level of MM inclusion in the diet estimated based on weight gain and FCR was 23.68 and 19.75%, respectively (P < 0.05). The gradual increase in MM levels replacing CM in the diet reduced the activity of the intestinal enzymes amylase, lipase, and alkaline protease (P < 0.05). In conclusion, we recommended replacing 19.75-23.68% of CM with MM, which can be used in piava diets. ABSTRACT Mangifera indica countries (CM (MM Megaleporinus obtusidens n 160 replications 4 0, 0 (0 33 66 100%. 100 . 100%) mold, mold (mold coliforms cereus Salmonellasp. Salmonellasp P 0.05. 005 0.05 05 0.05) (FCR secondorder second order analysis 2368 23 68 23.6 1975 19 75 19.75% amylase lipase conclusion 19.7523.68% 19752368 19.75 23.68% 19.75-23.68 16 ( 3 6 10 00 0.0 236 2 23. 197 1 7 7523 19.7523.68 1975236 19.7 19.75-23.6 0. 752 19.7523.6 197523 19. 19.75-23. 19.7523. 19752 19.75-23 19.7523 19.75-2 19.752 19.75-

https://doi.org/10.1590/0103-8478cr20230670

Synthesis, Antileishmanial Activity, and in silico Study of 2-Hydroxy 3 (1,2,3 triazolyl)propyl Vanillin Derivatives Synthesis Activity 2Hydroxy Hydroxy 2 1,2,3 123 1 (1,2, triazolylpropyl triazolyl propyl 1,2, 12 (1,2 1,2 (1, 1, (1 (
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Santiago, Samira S.

; Freitas, Camila S.

; Costa, Adilson V.

; Oliveira, Mariana B. de

; Faria, Aidene F. C.

; Belarmino, William S.

; Moura, Gisely F.

; Santos, Nayara A. dos

; Romão, Wanderson

; Lacerda Júnior, Valdemar

; Oliveira, Fabrício M. de

; Oliveira, Osmair V.

; Coelho, Eduardo A. F.

; Teixeira, Róbson R.

Journal of the Brazilian Chemical Society

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2025, Volume 36 N. 5 elocation e-20240200

Abstract: En | Text: En | PDF: En

This study details the preparation, antileishmanial assay, and in silico analysis of twenty 2-hydroxy-3-(1,2,3-triazolyl)propyl vanillin derivatives. These compounds were synthesized in three steps and evaluated against Leishmania infantum, Leishmania amazonensis, and Leishmania braziliensis promastigotes. Compounds 3s and 3t were the most effective, showing good activity against all Leishmania species tested. Molecular docking indicated that all compounds bind favorably to the sterol 14α-demethylase (CYP51) enzyme from L. infantum. ADMET (absorption, distribution, metabolism, excretion and toxicity) analysis indicated good oral bioavailability, non blood-brain barrier penetration, and high gastrointestinal absorption. Posaconazole and compounds 3e, 3s, and 3t remained stable in the CYP51 binding region during 100 ns molecular dynamics (MD) simulations. Root mean square deviation (RMSD) and root mean square fluctuations (RMSF) analyses from the MD trajectory revealed significant conformational fluctuations of the CYP51 N-terminal, suggesting occasional expulsion of 3e, potentially explaining its higher IC50 (half-maximal inhibitory concentration) values. Pairwise decomposition analyses from molecular mechanics Poisson-Boltzmann surface area (MM/PBSA) calculations highlighted the importance of hydrophobic residues in interacting with the synthesized derivatives. preparation assay 2hydroxy31,2,3triazolylpropyl 2hydroxy3123triazolylpropyl hydroxytriazolylpropyl 2 hydroxy 3 1,2,3 triazolyl propyl 1 derivatives infantum amazonensis promastigotes s t effective tested 14αdemethylase αdemethylase 14α demethylase α CYP (CYP51 L absorption, absorption (absorption distribution metabolism toxicity bioavailability bloodbrain blood brain penetration 3e e CYP5 10 (MD simulations RMSD (RMSD RMSF (RMSF Nterminal, Nterminal N terminal, terminal N-terminal IC IC5 halfmaximal half maximal concentration values PoissonBoltzmann Poisson Boltzmann MM/PBSA MMPBSA MM PBSA (MM/PBSA 2hydroxy31 3triazolylpropyl triazolylpropyl 123 1,2, (CYP5 2hydroxy3 12 1,2 (CYP 2hydroxy 1,

https://doi.org/10.21577/0103-5053.20240200

Post-COVID-19 dry eye negatively impacts the patient’s quality of life PostCOVID19 PostCOVID Post COVID 19 Post-COVID-1 patients patient s PostCOVID1 1 Post-COVID- Post-COVID
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Antunes-Foschini, Rosalia

; Costa, Ilen Ferreira

; Bonifácio, Lívia Pimenta

; Rocha, Eduardo Melani

; Messias, André

; Bollela, Valdes Roberto

; Bellissimo-Rodrigues, Fernando

Arquivos Brasileiros de Oftalmologia

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2025, Volume 88 N. 3 elocation e2024-0112

Abstract: En | Text: En | PDF: En

ABSTRACT Purpose: To describe the ophthalmological findings of dry eye disease and its relation to the quality of life of COVID-19 survivors. Methods: COVID-19 survivors who had previously been hospitalized at Hospital das Clínicas de Ribeirão Preto complex underwent an ophthalmological evaluation, which included a dry eye disease questionnaire, break-up time, fluorescein staining, and Schirmer test. We collected the presenting and best-corrected visual acuity, sociodemographic data, personal medical history, and scores from a self-reported quality of life questionnaire (WHOQOL-bref). According to the severity of the acute phase of the disease, the patients were classified into mild-to-moderate, severe, and critical groups. Results: Ninety-five patients (190 eyes) were evaluated 100 ± 44 days after the onset of COVID-19 symptoms. Of these, 83 patients (87.3%) completed the WHOQOL-bref questionnaire. Ten patients (12.0%) had mild-to-moderate COVID-19, 41 (49.4%) had severe COVID-19, and 32 (38.6%) had critical COVID-19. The median best-corrected visual acuity was logMAR 0 (0-1). Approximately 26.3% patients had a history of dry eye disease or severe dry eye symptoms (frequent or constant ocular dryness and irritation). There was an association between the proportion of patients with dry eye disease and the quality of life (p=0.014) and health (p=0.001). Furthermore, there was a significant trend between the proportion of patients with dry eye disease and how they rated their health and quality of life (p=0.0004 and 0.0027, respectively. Conclusions: There is a significant negative correlation between the proportion of patients with dry eye disease and their self-reported quality of life. Purpose COVID19 COVID 19 COVID-1 Methods evaluation breakup break up time staining test bestcorrected best corrected data selfreported self reported WHOQOLbref. WHOQOLbref WHOQOL bref . (WHOQOL-bref) mildtomoderate, mildtomoderate mild moderate, moderate groups Results Ninetyfive Ninety five 190 (19 eyes 10 4 these 8 87.3% 873 87 3 (87.3% 12.0% 120 12 (12.0% COVID19, 19, 49.4% 494 49 (49.4% 38.6% 386 38 6 (38.6% COVID19. 19. 01. 01 1 (0-1) 263 26 26.3 frequent irritation. irritation irritation) p=0.014 p0014 p 014 (p=0.014 p=0.001. p0001 p=0.001 001 (p=0.001) Furthermore p=0.0004 p00004 0004 (p=0.000 00027 0027 0.0027 respectively Conclusions COVID1 COVID- (WHOQOL-bref (1 87.3 (87.3 12.0 (12.0 49.4 (49.4 38.6 (38.6 (0-1 2 26. p=0.01 p001 (p=0.01 p000 p=0.00 00 (p=0.001 p=0.000 p0000 000 (p=0.00 0002 002 0.002 ( 87. (87. 12. (12. 49. (49. 38. (38. (0- p=0.0 p00 (p=0.0 0.00 (87 (12 (49 (38 (0 p=0. p0 (p=0. 0.0 (8 (4 (3 p=0 (p=0 0. p= (p= (p

https://doi.org/10.5935/0004-2749.2024-0112

Conidiobolomycosis with neurological commitment in sheep in Pará, Brazil Pará
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Barbosa, Camila Cordeiro

; Filho, Carlos Eduardo da Silva Ferreira

; Silveira, Natália da Silva e Silva

; Oliveira, Carlos Magno Chaves

; Ferreira, Tatiane Teles Albernaz

; Silveira, José Alcides Sarmento da

; Duarte, Marcos Dutra

; Costa, Paulo Sérgio Chagas da

; Pereira, Gabriela Oliveira

; Brito, Marilene de Farias

; Barbosa, José Diomedes

Ciência Rural

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2025, Volume 55 N. 2 elocation e20240016

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: O estudo foi realizado em um ovino, fêmea, de três anos de idade, da raça santa inês, procedente de uma propriedade localizada do município de Santo Antônio de Tauá, oeste do Pará. O animal acometido tinha histórico de exoftalmia no olho esquerdo, secreção nasal e dificuldade respiratória há mais de três meses. Ao exame físico o animal apresentava baixo escore corporal, apatia, assimetria facial unilateral, moderada exoftalmia unilateral esquerda, dispneia mista e exsudação nasal serossanguinolenta profusa unilateral. À necropsia, foi observada grande massa nasal, predominantemente branco-amarelada com áreas vermelho enegrecidas, de superfície irregular, finamente granular, úmida e friável. A massa invadia desde a junção mucocutânea do nariz esquerdo até as coanas, se infiltrava pelos seios nasais frontais, placa cribiforme e alcançava as meninges e a porção frontal do cérebro. À microscopia da superfície do epitélio nasal notou-se severa destruição dos cornetos e dos epitélios, evidenciada por extensas áreas de necrose com muitos debris celulares, ulceração e infecção bacteriana secundária. No sistema nervoso central (SNC) havia meningite piogranulomatosa com acentuada congestão de vasos, focos de necrose e inflamação granulomatosa. O diagnóstico de rinite granulomatosa de origem micótica associada ao fungo Conidiobolus lamprauges foi baseado nos achados da imuno-histoquímica. RESUMO ovino fêmea idade inês Tauá Pará meses corporal apatia esquerda necropsia brancoamarelada branco amarelada enegrecidas irregular granular friável coanas frontais cérebro notouse notou epitélios celulares secundária SNC (SNC vasos imunohistoquímica. imunohistoquímica imuno histoquímica. histoquímica imuno-histoquímica

ABSTRACT: The study was conducted on a 3-year-old female Santa Inês sheep from a property located in the municipality of Santo Antônio de Tauá, west of Pará. The affected animal had a history of exophthalmos in the left eye, nasal discharge, and breathing difficulty for more than three months. On physical examination, the animal had a low body score, apathy, unilateral facial asymmetry, moderate unilateral left exophthalmos, mixed dyspnea and unilateral profuse serosanguinous nasal discharge. At necropsy, a large nasal mass was observed, predominantly yellowish-white with blackish-red areas, with an irregular, finely granular, moist, and friable surface. The mass invaded from the mucocutaneous junction of the left nostril to the choanae, infiltrated the frontal sinuses, the cribiform plate, and reached the meninges and the frontal portion of the brain. Microscopy of the surface of the nasal epithelium showed severe destruction of the turbinates and epithelia, evidenced by extensive areas of necrosis with a large amount of cellular debris, ulceration, and secondary bacterial infection. In the central nervous system there was pyogranulomatous meningitis with marked vessel congestion, as well as foci of necrosis and granulomatous inflammation. Immunohistochemistry showed intense staining of numerous intralesional hyphae for antibodies against Conidiobolus lamprauges. The diagnosis of granulomatous rhinitis of mycotic origin associated with the Conidiobolus lamprauges was based on epidemiological, clinical-pathological, and immunohistochemical data. ABSTRACT 3yearold yearold 3 year old Tauá Pará eye discharge months examination score apathy asymmetry necropsy observed yellowishwhite yellowish white blackishred blackish red irregular granular moist choanae sinuses plate brain epithelia debris ulceration infection congestion inflammation epidemiological clinicalpathological, clinicalpathological clinical pathological, pathological clinical-pathological data

https://doi.org/10.1590/0103-8478cr20240016

Food insecurity and water insecurity measurement in Brazil: Sustainable Development Goals monitoring through experiential scales
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Salles-Costa, Rosana

; Cherol, Camilla Christine de Souza

; Palmeira, Poliana de Araújo

; Segall-Corrêa, Ana Maria

; Young, Sera Lewise

; Pérez-Escamilla, Rafael

; Lignani, Juliana de Bem

; Vianna, Rodrigo Pinheiro de Toledo

; Mata, Mayline Menezes da

; Medeiros, Maria Angélica Tavares de

; Pasquim, Elaine Martins

; Barbosa, Juliana Chaves

; Lima, Thainá Ferreira de

; García-Obregón, Olga Patrícia

; Gaitán-Rossi, Pablo

; Lima, Juliana Schober Gonçalves

; Grossi, Mauro Eduardo Del

; Voci, Silvia Maria

; Santos, Sandra Maria Chaves dos

; Melgar-Quiñonez, Hugo Ramiro

Cadernos de Saúde Pública

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2025, Volume 41 N. 2 elocation e00153524

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/0102-311xen153524

Translation into Portuguese (Brazil), cultural adaptation and validation of Parathyroid Assessment of Symptoms (PAS) in patients with chronic kidney disease and hyperparathyroidism Brazil, Brazil , (Brazil) PAS (PAS (Brazil
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Campos, Rafael Costa e

; Amaral, Rayssa Ruszkowski do

; Hentschke, Marta Ribeiro

; Toneto, Marcelo Garcia

; Poli-de-Figueiredo, Carlos Eduardo

Brazilian Journal of Nephrology

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dec 2024, Volume 46 N. 4 elocation e20220059

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: A doença renal crônica (DRC) está relacionada à elevada morbimortalidade e perda de qualidade de vida. Igualmente, o hiperparatireoidismo está associado à perda progressiva da função renal, com níveis aumentados de fosfato e diminuição de cálcio, que induzem secreção do paratormônio. Objetivos: Traduzir para língua portuguesa (Brasil), adaptar culturalmente e validar o questionário Parathyroid Symptoms Assessment (PAS), seguindo critérios de confiabilidade e validade em pacientes com DRC e hiperparatireoidismo. Métodos: Estudo metodológico e transversal, realizado no Hospital São Lucas/PUCRS, Porto Alegre, Brasil. O processo de validação do questionário PAS seguiu protocolos de estudos anteriores. Após tradução para o português, aplicou-se a 100 pacientes com hiperparatireoidismo secundário (HPTS) e terciário ou persistente (HPTT). Para dados de validação do PAS, os pacientes responderam ao questionário Short Form Health 36 (SF-36). Critérios de confiabilidade foram avaliados usando coeficiente de correlação intraclasse (CCI) e alfa de Cronbach (α-C). A validade foi avaliada pelo coeficiente de correlação de Spearman entre valores de PAS e SF-36. Resultados: A idade média dos participantes foi 55,6 ± 15,6 anos, 61% eram homens e 68% foram diagnosticados com HPTS. Entre 100 pacientes, 53% realizaram reteste de PAS (CCI = 0,83). A confiabilidade interna por α-C foi 0,86. Observaram-se correlações negativas entre questões do PAS e os domínios físico e mental do SF-36, que variaram de 0,3 a 0,7. Conclusão A versão brasileira do questionário PAS mostrou-se válida e confiável. O questionário PAS pode ser usado para avaliar qualidade de vida em pacientes brasileiros com hiperparatireoidismo que falam português. Introdução (DRC Igualmente cálcio paratormônio Objetivos Brasil, Brasil , (Brasil) (PAS) Métodos transversal LucasPUCRS Lucas PUCRS Lucas/PUCRS Alegre anteriores português aplicouse aplicou se 10 HPTS (HPTS HPTT. HPTT . (HPTT) 3 SF36. SF36 SF (SF-36) CCI αC. αC α C (α-C) 36. SF-36 Resultados 556 55 6 55, 156 15 15, anos 61 68 53 0,83. 083 0,83 0 83 0,83) 086 86 0,86 Observaramse Observaram SF36, 36, 03 0, 07 7 0,7 mostrouse mostrou confiável (Brasil (PAS 1 (HPTT SF3 (SF-36 (α-C SF-3 5 08 0,8 8 (SF-3 SF- (SF- (SF

Abstract Introduction: Chronic kidney disease (CKD) is related to high morbidity and mortality and loss of quality of life. Likewise, hyperparathyroidism is associated to progressive loss of renal function, with increased phosphate and decrease calcium levels, which induce the secretion of parathyroid hormone. Objectives: To translate into Portuguese (Brazil), culturally adapt and validate the questionnaire Parathyroid Symptoms Assessment (PAS), following reliability and validity criteria in patients with chronic kidney disease and hyperparathyroidism. Methods: Methodological and cross-sectional study, carried out at São Lucas Hospital/PUCRS, Porto Alegre, Brazil. The PAS questionnaire validation process followed protocols from previous studies. After translating into Portuguese, it was applied to 100 patients with secondary (SHPT) and tertiary or persistent (THPT) hyperparathyroidism. For PAS validation data, patients responded to the Short Form Health 36 (SF-36) questionnaire. Reliability criteria were evaluated using intraclass correlation coefficient (ICC) and Cronbach’s alpha (α-C). Validity was assessed by Spearman’s correlation coefficient between PAS and SF-36 values. Results: Participant’s mean age was 55.6 ± 15.6 years, 61% was male, and 68% was diagnosed with SHPT. Among 100 patients, 53% performed a PAS retest (ICC = 0.83). The internal reliability by α-C was 0.86. Negative correlations were observed between PAS questions and SF-36 physical and mental domains, which ranged from 0.3 to 0.7. Conclusion: The Brazilian version of the PAS questionnaire was found to be valid and reliable. The PAS questionnaire can be used to evaluate quality of life in Brazilian patients with hyperparathyroidism who speak Portuguese. Introduction CKD (CKD Likewise function levels hormone Objectives Brazil, Brazil , (Brazil) PAS, (PAS) Methods crosssectional cross sectional study HospitalPUCRS Hospital PUCRS Hospital/PUCRS Alegre studies 10 SHPT (SHPT THPT (THPT data 3 SF36 SF (SF-36 ICC Cronbachs Cronbach s αC. αC α C . (α-C) Spearmans Spearman SF-3 values Results Participants Participant 556 55 6 55. 156 15 15. years 61 male 68 53 0.83. 083 0.83 0 83 0.83) 086 86 0.86 domains 03 0. 07 7 0.7 Conclusion reliable (Brazil (PAS 1 SF3 (SF-3 (α-C SF- 5 08 0.8 8 (SF- (SF

https://doi.org/10.1590/2175-8239-jbn-2022-0059en

10.

Modelagem 3D de edificação gerada por fotogrametria com uso de Veículos Aéreos Não Tripulados (VANT) D VANT (VANT
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Costa, Rayana Pinto

; Fernandes, Luara Lopes de Araujo

; Muta, Luís Filipe

; Isatto, Eduardo Luis

; Costa, Dayana Bastos

Ambiente Construído

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dec 2024, Volume 24 elocation e131377

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Projetos de construção são sistemas altamente complexos que apresentam recorrentemente discrepâncias entre o trabalho planejado e o trabalho realizado. Tecnologias digitais, como a fotogrametria com VANTs (drones), são ferramentas de suporte promissoras nesse contexto. Assim, este estudo tem como objetivo avaliar os procedimentos de desenvolvimento e qualidade de um modelo 3D gerado por fotogrametria através de imagens capturadas por drone, comparando-o ao modelo as-designed BIM. Para isso, realizou-se um estudo de caso em uma habitação de interesse social localizada em Camaçari-BA. Comparado ao modelo BIM projetado, o modelo fotogramétrico apresentou um desvio dimensional médio de -1,68%. O modelo também apresentou inconsistências como oclusões e deformações. O estudo mostra que tanto esse desvio como a qualidade do modelo fotogramétrico obtido podem ser consideravelmente influenciados pela forma de coleta dos dados (ex. baixa quantidade e resolução das fotos). A principal contribuição do estudo é apresentar o potencial do uso do VANT para captura de imagens para geração de um modelo de fotogrametria. realizado digitais drones, drones , (drones) contexto Assim D drone comparandoo comparando asdesigned as designed isso realizouse realizou se CamaçariBA. CamaçariBA Camaçari BA. BA Camaçari-BA projetado 1,68%. 168 1 68 -1,68% deformações ex. ex (ex fotos. fotos . fotos) (drones 1,68% 16 6 -1,68 1,68 -1,6 1,6 -1, 1, -1 -

Abstract Construction projects are highly complex systems that recurrently present discrepancies between work-as-imagined and work-as-done. Digital technologies, such as photogrammetry using UAVs (drones), are promising support tools to cope with this problem. Therefore, this study aims to evaluate the procedures for developing and assessing the quality of a 3D model generated through photogrammetry from images captured by a drone, comparing it to the as-designed BIM model. Thus, a case study was carried out in a residential low-income housing construction project in Camaçari, Brazil. Compared to the as-designed BIM 3D model, the photogrammetric model presented an average dimensional deviation of -1.68%. The model also presented issues such as occlusions and deformations. The study highlights that both this deviation and the quality of the photogrammetric model can be significantly influenced by the data collection method (e.g., quantity and resolution of photos). The study's primary contribution lies in presenting the potential of UAV usage for image capture in photogrammetry model generation. workasimagined work imagined workasdone. workasdone done. done work-as-done technologies drones, drones , (drones) problem Therefore D drone asdesigned designed Thus lowincome low income Camaçari Brazil 1.68%. 168 1 68 -1.68% deformations e.g., eg e g (e.g. photos. photos . photos) studys s generation (drones 1.68% 16 6 -1.68 e.g. (e.g 1.68 -1.6 e.g 1.6 -1. 1. -1 -

https://doi.org/10.1590/s1678-86212024000100737

11.

Equações de volume para indivíduos jovens de Pinus taeda L. no Planalto Serrano Catarinense
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de Souza, Eduardo Luz Vuolo, Allan Felipe Costa Cysneiros, Vinicius

Revista Forestal Mesoamericana Kurú

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dec 2024, Volume 21 N. 49 Pages 1 - 8

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The objective of this study was to adjust linear and non-linear models to estimate the wood volume in young stands of Pinus taeda, filling the information gap for the first years of species' stands. The data analyzed derive from selective thinning in a 5-year-old experimental stand of P. taeda, established in the Experimental Forestry Area of the Federal University of Santa Catarina, in the municipality of Curitibanos, SC. The single-input volumetric models of Husch (linear and non-linear) and Kopezky (linear) were tested, using only the Diameter as a variable, and the double-input models of Schumacher-Hall (linear and non-linear) and Spurr (linear), using the Diameter and Total Height variables. All models were adjusted by the ordinary least squares method, using linear and non-linear regression analysis. The best selected single-input and double-input models were applied to an independent database for validation. The double-input models presented better performance than single-input models, but the variation in accuracy and efficiency was not significant. Schumacher-Hall model and the Husch and Kopezky fitted models presented more accurate estimates in relation to the models available in the literature. Therefore, we confirmed the hypothesis that equations for older individuals overestimate the volume of young trees. Then, the models adjusted in the present study provided an accurate estimate of the wood volume coming from young stands and from commercial use of the first thinning.

Resumo O objetivo deste estudo foi ajustar modelos lineares e não-lineares para estimar o volume de madeira em povoamentos jovens de Pinus taeda, preenchendo a lacuna existente de informações para os primeiros anos dos plantios da espécie. Os dados utilizados foram provenientes de um desbaste em um plantio experimental de P. taeda com 5 anos de idade, implantado na Área Experimental Florestal da Universidade Federal de Santa Catarina, no munícipio de Curitibanos, SC. Foram testados os modelos volumétricos de simples entrada de Husch (linear e não linear) e Kopezky (linear), utilizando apenas a variável Diâmetro, e os modelos de dupla entrada de Schumacher-Hall (linear e não linear) e Spurr (linear), usando as variáveis Diâmetro e Altura Total. Os modelos foram ajustados pelo método dos mínimos quadrados ordinários, utilizando análise de regressão linear e não-linear. O melhor modelo de simples entrada e o de dupla entrada foram aplicados a uma base de dados independentes para validação. Os modelos de dupla entrada apresentaram resultados superiores aos de simples entrada, porém a variação de acurácia e eficiência não foi tão considerável. O modelo de Schumacher-Hall e os modelos de Husch e Kopezky ajustados apresentaram melhores estimativas em relação aos modelos disponíveis na literatura. Portanto, a hipótese de que as equações para indivíduos com idades mais avançadas superestimam o volume dos indivíduos jovens foi aceita. Assim, os modelos ajustados no presente estudo forneceram estimativas mais acuradas do volume de madeira proveniente de povoamentos jovens e do aproveitamento comercial do primeiro desbaste.

https://doi.org/10.18845/rfmk.v21i49.7249

12.

Anaerobic mono-and co-digestion of fruit and vegetable residues: Effects on biogas yield and biofertilizer monoand mono codigestion co digestion residues
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Hinterholz, Bruna

; Costa, Mônica S. S. de M.

; Lucas Junior, Jorge de

; Pereira, Edilene da S.

; Buligon, Eduardo L.

; Lima, Jessica C. de

; Marostica, Ritieli

Revista Brasileira de Engenharia Agrícola e Ambiental

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nov 2024, Volume 28 N. 11 elocation e280349

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO A destinação adequada dos resíduos de frutas e vegetais é fundamental para promover a sustentabilidade ambiental, reduzir a pegada de carbono, melhorar a qualidade do solo e contribuir para a transição para uma economia circular. Neste estudo, foram avaliados os efeitos da adição de água residuária da bovinocultura de leite em codigestão anaeróbia com resíduos de frutas e vegetais e o uso do biofertilizante como diluente na monodigestão anaeróbia dos resíduos de frutas e vegetais (reciclo). A produção específica de biogás e metano, bem como a qualidade agronômica do biofertilizante em um estudo semicontínuo, foram avaliados. Foram utilizadas duas estratégias para partida dos reatores: o abastecimento inicial dos reatores totalmente com inóculo (biofertilizante proveniente da digestão anaeróbia da água residuária da bovinocultura de leite) e a progressão de carga para os resíduos de frutas e vegetais. A maior produção específica de biogás e metano foi atingida pela codigestão anaeróbia de resíduos de frutas e vegetais com água residuária da bovinocultura de leite, 720 e 436 L kg-1 de sólidos voláteis (SV), respectivamente. A adição da água residuária da bovinocultura de leite aumentou em 249% a alcalinidade dos resíduos de frutas e vegetais e diminuiu em 83,4% sua acidez volátil. A recuperação de macronutrientes no biofertilizante é favorecida pela monodigestão anaeróbia dos resíduos de frutas e vegetais em função do uso do reciclo. Entretanto, visando a destinação destes ao meio rural, a codigestão anaeróbia com água residuária da bovinocultura de leite favorece o uso agrícola do biofertilizante. ambiental carbono circular reciclo . (reciclo) semicontínuo 72 43 kg1 kg 1 kg- SV, SV , (SV) respectivamente 249 834 83 4 83,4 volátil Entretanto rural (reciclo 7 (SV 24 8 83, 2

ABSTRACT The proper disposal of fruit and vegetable waste is essential to promote environmental sustainability, reduce the carbon footprint, improve soil quality, and contribute to the transition to a circular economy. This study examined the impact of incorporating dairy cattle wastewater (DCWW) into anaerobic co-digestion with fruit and vegetable residues and utilization of the resulting biofertilizer as a diluent in the anaerobic mono-digestion of fruit and vegetable residues (recycle). The specific biogas and methane production and the agronomic quality of the biofertilizer were evaluated in a semi-continuous trial. Two startup strategies were employed: initially, the reactors were entirely fed with inoculum (biofertilizer derived from DCWW), and fruit and vegetable residue feedstock was gradually introduced. Anaerobic co-digestion of fruit and vegetable residues with DCWW yielded the highest specific production of biogas and methane at 720 and 436 L kg-1 of volatile solids (VS), respectively. The addition of DCWW increases fruit and vegetable residue alkalinity by 249% and reduces the volatile acidity by 83.4%. Anaerobic mono-digestion of fruit and vegetable residues enhances macronutrient recovery in the biofertilizer through recycle. Logistically, directing fruit and vegetable residues to rural areas for anaerobic co-digestion with DCWW promotes agricultural biofertilizer use. sustainability footprint economy (DCWW codigestion co digestion monodigestion mono recycle . (recycle) semicontinuous semi continuous trial employed initially DCWW, , DCWW) introduced 72 43 kg1 kg 1 kg- VS, VS (VS) respectively 249 834 83 4 83.4% Logistically use (recycle 7 (VS 24 8 83.4 2 83.

https://doi.org/10.1590/1807-1929/agriambi.v28n11e280349

13.

Piedraia hortae: biofilm formation and its importance in the pathogenesis of Piedra nigra (black piedra) hortae black piedra
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Almeida Junior, Hiram Larangeira de

; Assis, Thales Moura de

; Faria, Eduardo Camargo

; Costa, Luiz Roberto Kramer

; Ibaldo, Berenice Marques

Anais Brasileiros de Dermatologia

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nov 2024, Volume 99 N. 6 Pages 863 - 868

Abstract: En | Text: En | PDF: En

Abstract Background Little is known about the ultrastructure of Piedraia hortae. Objective To examine a P. hortae colony with scanning electron microscopy and investigate possible contributions to its the pathogenesis of black piedra. Results On low magnifications, two distinct aspects of the colony are identified, a compact area and a filamentous area. Analysis of the filamentous area demonstrates hyphae adhered by a thin reticular substance. A recurring finding is the adhesion between the fungal filaments in parallel. On high magnifications, the microfibrillar substance adhering the hyphae to each other becomes very evident. Examination of the compact area shows the hyphae embedded in the reticular matrix forming a biofilm and the colony well adhered. On high magnification, it can be observed that the hyphae are within this fibrillar matrix, which has the same appearance as the filamentous substance that adheres the hyphae to each other. Study limitations Only one strain was examined. Conclusions The formation of biofilm with fungal structures and reticulated extracellular substance is important in the pathogenesis of black piedra. P piedra magnifications identified parallel evident magnification examined

https://doi.org/10.1016/j.abd.2023.12.005

14.

Growth and bioactive compounds of baby-leaf chicory on colored cultivation benches with different wavelengths
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Araújo, Tassila Aparecida do Nascimento de Costa, Edilson Dantas, Thaise Binotti, Flávio Ferreira da Silva Vendruscolo, Eduardo Pradi Vieira, Gustavo Haralampidou da Costa Ribeiro, Fernanda Cristina Silva Lima, Sandro Marcio Andrade, Luis Humberto da Cunha

Chilean journal of agricultural research

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oct 2024, Volume 84 N. 5 Pages 653 - 662

Abstract: En | Text: En | PDF: En

ABSTRACT Care for human well-being and health requires the consumption of healthy foods, and therefore, the “baby-leaf” gains increased space in the market as they have higher concentrations of bioactive compounds. The present study aimed to evaluate the growth and bioactive compounds of baby-leaf chicory (Cichorium intybus L.) according to the color of cultivation benches with different wavelengths. The experiment was conducted in a non-acclimatized greenhouse, covered with low density polyethylene film with an aluminized screen of 50% shading under the film and 50% shading screens on the sides. In a completely randomized design, five types of benches were evaluated without and with bright reflective colored materials: Control bench without reflective material, a bench with reflective bright white laminate, reflective bright dark red laminate, reflective bright dark blue laminate, and reflective bright yellow laminate. The bright white and yellow laminates amplified the most photosynthetically active radiation. All the laminates enhanced yield of baby-leaf chicory plants, where white, yellow, red, and dark blue enhanced the fresh matter by 102.6%, 50.2%, 60.6%, and 37.4% compared to the control, respectively. The bright dark blue laminates enhanced the bioactive compounds of baby-leaf chicory plants. The bright dark blue laminate enhanced the carotenoid production of baby-leaf chicory plants by 11.0%. The use of colored laminates was effective in the cultivation of baby-leaf chicory, both in terms of yield and quality, with significant increases in fresh matter and bioactive compounds. To provide baby-leaf chicory with higher bioactive content with antioxidant effect (carotenoids) the use of dark blue laminates is necessary; however, if the objective is greater shoot DM it will be white laminates.

https://doi.org/10.4067/s0718-58392024000500653

15.

Clinical-epidemiological profile of leprosy patients undergoing retreatment at a reference center in southeastern Brazil Clinicalepidemiological Clinical epidemiological
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Bezerra, Guilherme Holanda

; Velho, Paulo Eduardo Neves Ferreira

; França, Andréa Fernandes Eloy da Costa

Anais Brasileiros de Dermatologia

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oct 2024, Volume 99 N. 5 Pages 766 - 768

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.abd.2023.09.006

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