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Resumo Neospora caninum é uma das principais causas de perda reprodutiva em bovinos em todo o mundo, pois leva ao aborto e ao reposicionamento animal. Embora o Toxoplasma gondii não cause problemas reprodutivos em bovinos, o consumo de carne bovina crua ou não cozida apresenta risco de transmissão. Este estudo teve como objetivo avaliar a ocorrência de anticorpos anti-N. caninum e anti-T. gondii em bovinos leiteiros nas regiões Oeste e Noroeste do Estado de São Paulo, Brasil. Um total de 653 amostras de soro de bovinos leiteiros, foi analisado utilizando-se o ensaio de imunofluorescência indireta (IFI). Os dados epidemiológicos das propriedades foram associados aos resultados sorológicos dos animais por meio de regressão logística. As frequências dos anticorpos contra N. caninum e T. gondii foram 41,6% (272/653) e 11,5% (75/653), respectivamente. Foi observada associação estatisticamente significativa entre: soropositividade para N. caninum e raça, histórico de suplementação alimentar para bezerros, introdução de animais externos que, posteriormente, apresentaram problemas reprodutivos e histórico de problemas reprodutivos no segundo trimestre de gestação. O presente estudo destaca a importância da neosporose em bovinos leiteiros, nas regiões de estudo, e a inclusão deste parasita na investigação de animais com distúrbios reprodutivos é fundamental. mundo animal transmissão antiN. antiN anti N anti-N antiT. antiT T anti-T Paulo Brasil 65 utilizandose utilizando se IFI. IFI . (IFI) logística 416 41 6 41,6 272/653 272653 272 (272/653 115 11 5 11,5 75/653, 75653 75/653 , 75 (75/653) respectivamente entre raça bezerros que posteriormente gestação fundamental (IFI 4 41, 272/65 27265 27 (272/65 1 11, 7565 75/65 7 (75/653 272/6 2726 2 (272/6 756 75/6 (75/65 272/ (272/ 75/ (75/6 (272 (75/ (27 (75 (2 (7 (

Abstract Neospora caninum is a major cause of reproductive loss in cattle worldwide as it leads to abortion and animal repositioning. Although Toxoplasma gondii does not cause a reproductive problem in cattle, consuming raw or uncooked beef poses the risk of transmission. This study aimed to evaluate the occurrence of anti-N. caninum and anti-T. gondii antibodies in dairy cattle in the West and Northwest regions of São Paulo State, Brazil. A total of 653 serum samples from dairy cows were analyzed using an indirect immunofluorescence assay (IFA). Epidemiological data from the farms were associated with the serological results of the animals by logistic regression based on the presence of antibodies. The frequencies of the antibodies against N. caninum and T. gondii were 41.6% (272/653) and 11.5% (75/653), respectively. A statistically significant association was observed between: the serum anti-N. caninum antibodies and breed, history of food supplementation for calves, introduction of outside animals that later presented reproductive problems, and history of reproductive problems by the trimester of gestation. The present study highlights the importance of neosporosis in dairy cattle in the study regions and that the inclusion of this parasite in the investigation of animals with reproductive disorders is important. repositioning transmission antiN. antiN anti N anti-N antiT. antiT T anti-T State Brazil 65 IFA. IFA . (IFA) 416 41 6 41.6 272/653 272653 272 (272/653 115 11 5 11.5 75/653, 75653 75/653 , 75 (75/653) respectively between breed calves gestation important (IFA 4 41. 272/65 27265 27 (272/65 1 11. 7565 75/65 7 (75/653 272/6 2726 2 (272/6 756 75/6 (75/65 272/ (272/ 75/ (75/6 (272 (75/ (27 (75 (2 (7 (

https://doi.org/10.1590/s1984-29612024034

Comparative analysis between open transvesical and laparoscopic adenomectomy in the treatment of benigne prostatic hyperplasia in a tertiary hospital in Curitiba-PR: a retrospective study CuritibaPR Curitiba PR Curitiba-PR
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SFREDO, LUCIANO RICARDO

; OLIVEIRA, ISABELLA CORREA DE

; NOVAKOSKI, GUILHERME KYUZAEMON OSAKO

; DIGNER, INGRIDY DE SOUZA

; SILVA, IVAM VARGAS MARTINS DA

; LACERDA, DANIEL AUGUSTO MAUAD

; CAMPOS, BRUNO CESAR MOLINA MALTAURO

; SANTOS, LUIZ SÉRGIO

Revista do Colégio Brasileiro de Cirurgiões

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2023, Volume 50 elocation e20233450

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: o objetivo deste estudo foi comparar o resultado das técnicas de prostatectomia transvesical aberta e videolaparoscópica no tratamento de hiperplasia prostática benigna (HPB) em um hospital terciário. Métodos: foram revisados prontuários de pacientes submetidos a adenectomia transvesical devido a HPB entre março de 2019 a março de 2021 no serviço de urologia do Hospital de Clínicas do Paraná (HCPR), sendo incluídos 42 pacientes no grupo prostatectomia transvesical aberta e 22 no grupo videolaparoscópico. Em seguida foi feita a comparação entre as técnicas nos quesitos tempo cirúrgico, sangramento, tempo de internamento, necessidade de terapia intensiva, entre outras, além de desfecho pós-operatório. Resultados: o tempo cirúrgico médio foi menor na técnica aberta em comparação com a técnica videolaparoscópica (141 min vs 274 min). O grupo videolaparoscópico apresentou um tempo médio de internamento menor (3,5 dias vs 6,36 dias). Não houve significância estatística na comparação quanto a necessidade de unidade de terapia intensiva, assim como na avaliação do sangramento pós-operatório. Conclusão: comparativamente, as técnicas demonstraram um desfecho semelhante, com baixa taxa de complicações e resultados satisfatórios para o tratamento da HPB. Sendo a técnica videolaparoscópica uma cirurgia com menor tempo de internamento, porém às custas de um maior tempo cirúrgico. . Objetivo (HPB terciário Métodos 201 202 HCPR, HCPR , (HCPR) 4 2 intensiva outras pósoperatório. pósoperatório pós operatório. operatório pós-operatório Resultados 141 (14 27 min. min) 3,5 35 3 5 (3, 636 6 36 6,3 dias. dias) Conclusão comparativamente semelhante 20 (HCPR 14 (1 3, (3 63 6, 1 (

ABSTRACT Objective: the aim of this study was to compare the results of open and videolaparoscopic transvesical prostatectomy techniques in the treatment of benign prostatic hyperplasia (BPH) in a tertiary hospital. Methods: we reviewed medical records of patients who underwent transvesical adenectomy due to BPH between March 2019 and March 2021 at the urology service of Hospital de Clínicas do Paraná (HCPR), 42 patients were included in the open transvesical prostatectomy group and 22 in the videolaparoscopic group. Then, a comparison was made between the techniques in terms of surgical time, bleeding, length of stay, need for intensive care, among others, in addition to postoperative outcome. Results: the mean surgical time was shorter in the open technique compared to the laparoscopic technique (141 min vs 274 min). The videolaparoscopic group had a shorter mean hospital stay (3.5 days vs 6.36 days). There was no statistical significance in the comparison regarding the need for an intensive care unit, as well as in the assessment of postoperative bleeding. Conclusion: comparatively, the techniques demonstrated a similar outcome, with a low rate of complications and satisfactory results for the treatment of BPH. The laparoscopic technique is a surgery with a shorter hospital stay, but at the expense of a longer surgical time. Objective (BPH Methods 201 202 HCPR, HCPR , (HCPR) 4 2 Then bleeding others outcome Results 141 (14 27 min. . min) 3.5 35 3 5 (3. 636 6 36 6.3 days. days) unit Conclusion comparatively 20 (HCPR 14 (1 3. (3 63 6. 1 (

https://doi.org/10.1590/0100-6991e-20233450-en

Quali-quantitative evidence on water quality by a governance process with payment for environmental services in a water supply watershed Qualiquantitative Quali quantitative
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Freitas Júnior, Frederico Luiz de

; Pereira, Mariana de Souza

; Fernandes, Cristovão Vicente Scapulatempo

; Fan, Fernando Mainardi

; Costa, Reginaldo Brito da

; Magalhães Filho, Fernando Jorge Correa

RBRH

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2023, Volume 28 elocation e40

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Para uma gestão eficiente da conservação da água e do solo, os aspectos de qualidade e quantidade devem ser integrados. No entanto, ainda faltam estudos com essa sinergia incluindo o processo de governança. Avaliamos aspectos de quali-quantidade (2010-2019) por 10 anos em um manancial de abastecimento de água e a implementação de Pagamentos por Serviços Ambientais (PSA), para entender a eficiência da política pública na área ambiental e seus efeitos sobre os recursos hídricos. O processo de governança foi investigado e análises estatísticas usadas para comparação de médias, análises gráficas (tendências, série temporal, curva de permanência, desvio padrão), correlação e multivariada para avaliar o comportamento dos parâmetros, após implementação do PSA. Nossos resultados mostraram que houve uma redução significativa na turbidez, DQO e sólidos suspensos totais. Além disso, a vazão, nitrogênio total, fósforo total e oxigênio dissolvido permaneceram estáveis, após a implementação de práticas de conservação, corroborada pela análise multivariada. O índice de qualidade da água (IQA) entre “Bom” e “Ótimo” e os parâmetros químicos e hidrobiológicos abaixo dos valores máximos permitidos, refletiram na manutenção da qualidade da água. A tomada de decisão participativa com base no diálogo entre as partes interessadas e a confiança no PSA foram os elementos-chave de sucesso. solo integrados entanto qualiquantidade quali 20102019 2010 2019 (2010-2019 1 PSA, , (PSA) hídricos médias tendências, tendências (tendências temporal permanência padrão, padrão padrão) turbidez totais disso vazão estáveis IQA (IQA Bom “Bom Ótimo “Ótimo permitidos elementoschave elementos chave sucesso 2010201 201 (2010-201 (PSA 201020 20 (2010-20 20102 2 (2010-2 (2010- (2010 (201 (20 (2 (

ABSTRACT For the efficient management of water and soil conservation, quality and quantity aspects must be integrated. However, there is still a lack of studies with this synergy including governance processes. The present research evaluated for ten years (2010-2019) quality and quantity aspects of a water supply source and the Payment for Environmental Services (PES) implementation to investigate public policy efficiency and its effect on water resources. We used statistical analyses for comparing means, graphical analyses (trends, time series, duration curve, standard deviation), and correlation and multivariate analysis to evaluate parameters’ behavior after the PES implementation. Results showed that there was a significant reduction in turbidity, COD, and total suspended solids. Furthermore, water flow rate, total nitrogen, total phosphorus, and dissolved oxygen remained stable after the implementation of conservation practices, as confirmed by the multivariate analysis. Water quality index (WQI) between “Good” and “Great” and chemical and hydrobiological parameters below the maximum allowed values reflected on the water quality maintenance. Participative decision-making based on dialogue between stakeholders and trust in PES were key elements for success. integrated However processes 20102019 2010 2019 (2010-2019 (PES resources means trends, trends (trends series curve deviation, deviation , deviation) turbidity COD solids Furthermore rate nitrogen phosphorus practices WQI (WQI Good “Good Great “Great maintenance decisionmaking decision making success 2010201 201 (2010-201 201020 20 (2010-20 20102 2 (2010-2 (2010- (2010 (201 (20 (2 (

https://doi.org/10.1590/2318-0331.282320230007

Reading fluency during the COVID-19 pandemic: a longitudinal and cross-sectional analysis COVID19 COVID 19 COVID-1 pandemic crosssectional cross sectional COVID1 1 COVID-
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Alves, Luciana Mendonça

; Carvalho, Isa Mourão

; Santos, Luiz Felipe dos

; Ribeiro, Gabriela de Lima

; Freire, Laura de Souza Cardoso

; Martins-Reis, Vanessa de Oliveira

; Labanca, Ludimila

; Celeste, Letícia Correa

Arquivos de Neuro-Psiquiatria

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oct 2022, Volume 80 N. 10 Pages 994 - 1003

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Antecedentes Estudos internacionais realizados durante os períodos de isolamento social destacaram a potencial perda das habilidades de aprendizagem dos alunos. O presente estudo preenche uma lacuna nas pesquisas brasileiras sobre este tema, e se centra no desenvolvimento da fluência de leitura. Objetivo Investigar o desenvolvimento da fluência de leitura de alunos nos anos iniciais do Ensino Fundamental durante as aulas remotas ministradas em decorrência das medidas de distanciamento social postas em prática por conta da pandemia de doença do coronavírus 2019 (coronavirus disease 2019, COVID-19, em inglês). Métodos Estudantes do 2o ao 5o anos foram gravados. Foram analisadoso número de palavras lidas por minuto e o de palavras lidas corretamente por minuto. Realizou-se análise estatística descritiva por meio de análise de variância (analysis of variance, ANOVA, em inglês) para medidas repetidas com correção de Bonferroni no estudo longitudinal, e teste T no estudo transversal. Resultados Ao todo, 162 estudantes participaram do estudo transversal. Apenas a comparação entre as turmas de 2o ano de 2020 e 2021 apresentou diferença estatisticamente significativa. Nas aulas pré-pandemia, as turmas apresentaram resultados melhores em termos de precisão de leitura do que as turmas avaliadas durante a pandemia. O estudo longitudinal incluiu 75 alunos; entre março e dezembro de 2020, eles melhoraram sua taxa de fluência e acurácia, conforme esperado. Em março de 2021, os resultados mostraram uma queda, o que pode estar relacionado ao fechamento das escolas durante as férias. Conclusões Esta pesquisa demonstra os resultados do desenvolvimento da leitura de uma amostra de estudantes brasileiros durante a pandemia. Houve uma evolução expressiva no 2° e 3° anos, com estabilidade nos anos seguintes. A turma de 2° ano de 2021 sofreu um grande impacto devido à pandemia. tema 201 coronavirus COVID19, COVID19 COVID 19, 19 COVID-19 inglês. inglês . gravados Realizouse Realizou analysis variance ANOVA transversal todo 16 202 significativa prépandemia, prépandemia pré pandemia, pré-pandemia 7 acurácia esperado queda férias 2 3 seguintes 20 COVID1 1 COVID-1 COVID-

Abstract Background International studies performed during the periods of social isolation highlighted the potential loss of student's learning skills. The present study fills a gap in Brazilian research on this topic and focuses on the development of reading fluency. Objective To investigate the development of the reading fluency of students in the early years of elementary school during e-learning as a result of the social distancing measures put into effect due to the coronavirus disease 2019 (COVID-19) pandemic. Methods Students from grades 2 to 5 were recorded. The number of words read per minute and of those read correctly per minute were analyzed. Descriptive statistical analysis was performed, using analysis of variance (ANOVA) for repeated measures with Bonferroni correction in the longitudinal study, and the t-test in the cross-sectional study. Results In the cross-sectional study, 162 students participated. Only the comparison between the 2nd grade classes of 2020 and 2021 showed a statistically significant difference. In the prepandemic classes, the students had better results in reading accuracy than the students assessed during the pandemic. The longitudinal study included 75 students, who improved in fluency rate and accuracy as expected between March and December 2020. In March 2021, the results showed a drop, which may be related to school closures during the Brazilian summer vacation. Conclusions The present research demonstrates the results of Brazilian students in terms of the development of reading fluency during the pandemic. There was an expressive development in grades 2 and 3, with stability in the following grades. The 2nd grade class of 2021 suffered a major impact due to the pandemic. student s skills elearning e 201 COVID19 COVID 19 (COVID-19 pandemic recorded analyzed ANOVA (ANOVA ttest t test crosssectional cross sectional 16 participated nd 202 difference 7 drop vacation 3 20 COVID1 1 (COVID-1 (COVID- (COVID

https://doi.org/10.1055/s-0042-1758446

Leaf extract of Coffea arabica L. reduces lipid peroxidation and has anti-platelet effect in a rat dyslipidemia model
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Simões, Mario Henrique Souza

; Salles, Bruno Cesar Correa

; Duarte, Stella Maris da Silveira

; Silva, Marcelo Aparecido da

; Viana, André Luiz Machado

; Moraes, Gabriel de Oliveira Isaac de

; Figueiredo, Sonia Aparecida

; Ferreira, Eric Batista

; Rodrigues, Maria Rita

; Paula, Fernanda Borges de Araújo

Brazilian Journal of Pharmaceutical Sciences

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2022, Volume 58 elocation e19562

Abstract: En | Text: En | PDF: En

Abstract This study aimed to evaluate the antioxidant potential of the Coffea arabica Lineu (L.) leaf extract and its effects on platelet aggregation of dyslipidemic rats. The extract was obtained by the percolation of C. arabica L. leaves in hydroethanolic solution 70% (v/v). The mass spectrometry FIA-ESI-MS² suggested the presence of chlorogenic acid, rutin acid, and quinic acid. The DPPH• radicals scavenging capacity was demonstrated (IC50 = 0.06 mg/mL). The extract was administered to rats by gavage (300 mg/kg/day) for 56 days. Dyslipidemia was induced by administering Triton WR-1339 (300 mg/kg body weight) on the 54th day. On day 56, blood was collected by puncturing the abdominal aorta artery and the aortic artery was removed. Lipid profile, markers of renal and hepatic injury, lipid peroxidation, and platelet aggregation tests were carried out. The ingestion of extract reduced the lipid peroxidation (aorta and plasma) and platelet aggregation in dyslipidemic rats. The extract did not affect markers of renal and hepatic function as analyzed in this study, suggesting neither impaired liver nor kidney function in these animals. Therefore, our results demonstrate that the extract of leaves of C. arabica L. show antioxidant potential in vitro and in vivo as well as anti-platelet aggregation in dyslipidemic animals.

https://doi.org/10.1590/s2175-97902022e19562

Diretrizes da Sociedade Brasileira de Cardiologia sobre Angina Instável e Infarto Agudo do Miocárdio sem Supradesnível do Segmento ST – 2021
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Nicolau, José Carlos

; Feitosa Filho, Gilson Soares

; Petriz, João Luiz

; Furtado, Remo Holanda de Mendonça

; Précoma, Dalton Bertolim

; Lemke, Walmor

; Lopes, Renato Delascio

; Timerman, Ari

; Marin Neto, José A.

; Bezerra Neto, Luiz

; Gomes, Bruno Ferraz de Oliveira

; Santos, Eduardo Cavalcanti Lapa

; Piegas, Leopoldo Soares

; Soeiro, Alexandre de Matos

; Negri, Alexandre Jorge de Andrade

; Franci, Andre

; Markman Filho, Brivaldo

; Baccaro, Bruno Mendonça

; Montenegro, Carlos Eduardo Lucena

; Rochitte, Carlos Eduardo

; Barbosa, Carlos José Dornas Gonçalves

; Virgens, Cláudio Marcelo Bittencourt das

; Stefanini, Edson

; Manenti, Euler Roberto Fernandes

; Lima, Felipe Gallego

; Monteiro Júnior, Francisco das Chagas

; Correa Filho, Harry

; Pena, Henrique Patrus Mundim

; Pinto, Ibraim Masciarelli Francisco

; Falcão, João Luiz de Alencar Araripe

; Sena, Joberto Pinheiro

; Peixoto, José Maria

; Souza, Juliana Ascenção de

; Silva, Leonardo Sara da

; Maia, Lilia Nigro

; Ohe, Louis Nakayama

; Baracioli, Luciano Moreira

; Dallan, Luís Alberto de Oliveira

; Dallan, Luis Augusto Palma

; Mattos, Luiz Alberto Piva e

; Bodanese, Luiz Carlos

; Ritt, Luiz Eduardo Fonteles

; Canesin, Manoel Fernandes

; Rivas, Marcelo Bueno da Silva

; Franken, Marcelo

; Magalhães, Marcos José Gomes

; Oliveira Júnior, Múcio Tavares de

; Filgueiras Filho, Nivaldo Menezes

; Dutra, Oscar Pereira

; Coelho, Otávio Rizzi

; Leães, Paulo Ernesto

; Rossi, Paulo Roberto Ferreira

; Soares, Paulo Rogério

; Lemos Neto, Pedro Alves

; Farsky, Pedro Silvio

; Cavalcanti, Rafael Rebêlo C.

; Alves, Renato Jorge

; Kalil, Renato Abdala Karam

; Esporcatte, Roberto

; Marino, Roberto Luiz

; Giraldez, Roberto Rocha Corrêa Veiga

; Meneghelo, Romeu Sérgio

; Lima, Ronaldo de Souza Leão

; Ramos, Rui Fernando

; Falcão, Sandra Nivea dos Reis Saraiva

; Dalçóquio, Talia Falcão

; Lemke, Viviana de Mello Guzzo

; Chalela, William Azem

; Mathias Júnior, Wilson

Arquivos Brasileiros de Cardiologia

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jul 2021, Volume 117 N. 1 Pages 181 - 264

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20210180 3052 downloads

Evolução da velocidade de leitura no Ensino Fundamental I e II
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Alves, Luciana Mendonça

; Santos, Luiz Felipe dos

; Miranda, Izabel Cristina Campolina

; Carvalho, Isa Mourão

; Ribeiro, Gabriela de Lima

; Freire, Laura de Souza Cardoso

; Martins-Reis, Vanessa de Oliveira

; Celeste, Letícia Correa

CoDAS

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2021, Volume 33 N. 5 elocation e20200168

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo Verificar a influência da escolaridade em medidas de velocidade de leitura no ensino fundamental e explorar os níveis de precisão das variáveis da velocidade de leitura nos estágios de investigação epidemiológica de casos. Método Participaram 535 escolares do 2º ao 9º ano de escola particular e pública. A leitura oral de um texto simples foi avaliada nos parâmetros palavras lidas por minuto e palavras lidas corretamente por minuto. Foram conduzidas medidas de estatística descritiva e teste T de student com significância de 5%, além do escore Z, padronizado e individual. Resultados Os resultados corroboram a literatura que evidencia aumento da velocidade de leitura com a progressão da escolaridade. A fluência leitora se mostrou em processo de construção entre o 2º e o 7º ano do Ensino Fundamental, com estabilização a partir do 7º ano. Uma leitura mais fluente e homogênea se mostrou sedimentada entre o 7º e o 9º ano. O estudo propõe a interpretação dos achados com escalas sugestivas para déficit por meio do z-escore. Os dados são estratificados desde valores sugestivos de déficit importante até o não sugestivo, com um total de cinco estratos. A estratificação permite uma referência mais clara sobre qual ponto se encontra o escolar nas faixas esperadas para sua escolaridade. Conclusão As medidas dos valores esperados segundo a escolaridade são essenciais para melhor conhecimento do desenvolvimento da leitura, de forma a prover padrões de referência para um adequado monitoramento no âmbito clínico e educacional e predição das habilidades e dificuldades leitoras.

ABSTRACT Purpose To verify the influence of schooling on reading speed measures in Elementary School and Junior High, also aims to explore the levels of accuracy of the variables of reading speed in the epidemiological investigation stages of cases. Methods 535 students from the 2nd to the 9th grade from a private school and a state school system participated in the study. The oral reading of a simple text was evaluated in the following parameters: words read per minute and correctly words read per minute. Descriptive statistics and T-test measures with the significance of 5% were conducted, besides the z-score, standardized and individual. Results The results corroborate the literature review which shows an increase in reading speed with the progression of schooling. The reading fluency was presented in the construction process between the 2nd and 7th grades, with stabilization from the 7th year. A more fluent and homogeneous reading was sedimented between the 7th and 9th grades. The study proposes the interpretation of the findings with scales suggestive of the deficit using the z-score. The data are stratified from values suggestive of significant deficit to non-suggestive, with a total of five strata. The stratification allows a clearer reference on which point the scholar found in the expected ranges for their schooling. Conclusion The measures of the expected values according to schooling are essential for better-quality knowledge of reading development, to provide reference standards for adequate monitoring in the clinical and educational sphere and prediction of reading skills and difficulties.

https://doi.org/10.1590/2317-1782/20202020168 254 downloads

PROCESSAMENTO E APLICAÇÃO DE BIOMATERIAIS POLIMÉRICOS: AVANÇOS RECENTES E PERSPECTIVAS
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Bernardo, Marcela Piassi

; Paschoalin, Rafaella Takehara

; Santos, Danilo Martins dos

; Bilatto, Stanley

; Farinas, Cristiane Sanchez

; Correa, Daniel Souza

; Oliveira Jr., Osvaldo N.

; Mattoso, Luiz Henrique Capparelli

Química Nova

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2021, Volume 44 N. 10 Pages 1311 - 1327

Abstract: Pt | Text: Pt | PDF: Pt

Biomaterials have been intensively investigated due to the increase in the elderly population and high prevalence of several disorders, such as cardiovascular and orthopedic diseases. Polymeric and composite polymeric materials in combination with different processing techniques, such as electrospinning, solution blow spinning, ultrathin film preparation, and 3D printing are promising for obtaining biomaterials with patient-specific applications. Here, we provide a review on recent advances and perspectives for synthetic and natural polymers as well as composites in the design of biomaterials. After introducing basic information about biomaterials, we describe the fundamentals of manufacturing techniques and highlight possible biomedical applications.

https://doi.org/10.21577/0100-4042.20170781

Updated Cardiovascular Prevention Guideline of the Brazilian Society of Cardiology - 2019
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Précoma, Dalton Bertolim

; Oliveira, Gláucia Maria Moraes de

; Simão, Antonio Felipe

; Dutra, Oscar Pereira

; Coelho, Otávio Rizzi

; Izar, Maria Cristina de Oliveira

; Póvoa, Rui Manuel dos Santos

; Giuliano, Isabela de Carlos Back

; Alencar Filho, Aristóteles Comte de

; Machado, Carlos Alberto

; Scherr, Carlos

; Fonseca, Francisco Antonio Helfenstein

; Santos Filho, Raul Dias dos

; Carvalho, Tales de

; Avezum Jr., Álvaro

; Esporcatte, Roberto

; Nascimento, Bruno Ramos

; Brasil, David de Pádua

; Soares, Gabriel Porto

; Villela, Paolo Blanco

; Ferreira, Roberto Muniz

; Martins, Wolney de Andrade

; Sposito, Andrei C.

; Halpern, Bruno

; Saraiva, José Francisco Kerr

; Carvalho, Luiz Sergio Fernandes

; Tambascia, Marcos Antônio

; Coelho-Filho, Otávio Rizzi

; Bertolami, Adriana

; Correa Filho, Harry

; Xavier, Hermes Toros

; Faria-Neto, José Rocha

; Bertolami, Marcelo Chiara

; Giraldez, Viviane Zorzanelli Rocha

; Brandão, Andrea Araújo

; Feitosa, Audes Diógenes de Magalhães

; Amodeo, Celso

; Souza, Dilma do Socorro Moraes de

; Barbosa, Eduardo Costa Duarte

; Malachias, Marcus Vinícius Bolívar

; Souza, Weimar Kunz Sebba Barroso de

; Costa, Fernando Augusto Alves da

; Rivera, Ivan Romero

; Pellanda, Lucia Campos

; Silva, Maria Alayde Mendonça da

; Achutti, Aloyzio Cechella

; Langowiski, André Ribeiro

; Lantieri, Carla Janice Baister

; Scholz, Jaqueline Ribeiro

; Ismael, Silvia Maria Cury

; Ayoub, José Carlos Aidar

; Scala, Luiz César Nazário

; Neves, Mario Fritsch

; Jardim, Paulo Cesar Brandão Veiga

; Fuchs, Sandra Cristina Pereira Costa

; Jardim, Thiago de Souza Veiga

; Moriguchi, Emilio Hideyuki

; Schneider, Jamil Cherem

; Assad, Marcelo Heitor Vieira

; Kaiser, Sergio Emanuel

; Lottenberg, Ana Maria

; Magnoni, Carlos Daniel

; Miname, Marcio Hiroshi

; Lara, Roberta Soares

; Herdy, Artur Haddad

; Araújo, Cláudio Gil Soares de

; Milani, Mauricio

; Silva, Miguel Morita Fernandes da

; Stein, Ricardo

; Lucchese, Fernando Antonio

; Nobre, Fernando

; Griz, Hermilo Borba

; Magalhães, Lucélia Batista Neves Cunha

; Borba, Mario Henrique Elesbão de

; Pontes, Mauro Ricardo Nunes

; Mourilhe-Rocha, Ricardo

Arquivos Brasileiros de Cardiologia

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oct 2019, Volume 113 N. 4 Pages 787 - 891

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.5935/abc.20190204 40841 downloads

10.

Chitosan Nanocomposites with Graphene-Based Filler
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Maraschin, Thuany Garcia

; Correa, Roberto da Silva

; Rodrigues, Luiz Frederico

; Balzarettid, Naira Maria

; Malmonge, José Antonio

; Galland, Griselda Barrera

; Basso, Nara Regina de Souza

Materials Research

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2019, Volume 22 elocation e20180829

Abstract: En | Text: En | PDF: En

This study evaluates the properties of chitosan (CS) membranes modified with different percentages (0.5%, 3%, and 5% w/w) of a graphene-based material. Graphene oxide (GO) and reduced graphene oxide (RGO) were obtained by the chemical exfoliation of graphite and thermal reduction. Then, they were characterized by electrical conductivity measurements, FESEM, XRD, AFM, and Raman spectroscopy. The composites’ morphology was evaluated by FESEM. The degree of swelling over a 48 h period and mass loss behavior in phosphate-buffered saline solution for up to 70 days were also studied. The hydrophilicity of the CS and CS/graphene nanocomposites was examined by water contact angle. The graphene materials showed small stacks (6-8 sheets) with low defect density and nanoscale thickness (1.3-5.9 nm). The dispersion of the graphene material in the CS matrix significantly decreased the degree of swelling (460%) but did not modify the hydrolytic degradation process and the hydrophilicity of membranes.

https://doi.org/10.1590/1980-5373-mr-2018-0829 904 downloads

11.

Climate Forecasts at the Centro de Lançamento de Alcântara Using the Climate Model RegCM4
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Corrêa, Cleber Souza

; Camillo, Gerson Luiz

; Couto, Vinicius Milanez

; Fisch, Gilberto

; Correa, Felipe do Nascimento

; Harter, Fabricio

Journal of Aerospace Technology and Management

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mar 2017, Volume 9 N. 1 Pages 18 - 28

Abstract: En | Text: En | PDF: En

ABSTRACT: This study uses climate modeling (RegCM4 Climate Model) to provide a wind forecast average behavior at low levels, close to the surface. The model was used to generate an estimate of the average vertical wind profile lasting 5 months, from August to December 2015, attempting to observe intra-seasonal variations, with the presence of persistence in the wind field. The results of climate modeling of the wind profile near the surface have the great potential for great operational significance during launch campaigns at the Centro de Lançamento de Alcântara. Three average results were generated for the month of November 2015, while operating in São Lourenço. A dynamical downscaling nested with global models with RCP4.5 and RCP8.5, using 3 different global conditions initialization datasets. It used subsets with the models from the Met Office Hadley Centre (HadGEM2-ES), the Centre National de Recherches Météorologiques (CNRM-CM5), and the Commonwealth Scientific and Industrial Research Organization (CSIRO-Mk3.6), making a downscaling with the RegCM4 Climate Model for the Centro de Lançamento de Alcântara region. The results are preliminary but show great potential. Since the RegCM4 Climate Model can show variations of high and low intensity, its temporal frequency in the average vertical wind profile and the duration of temporal variation are of the order of 3 - 5 days. The RegCM4 Climate Model had better results with the one from the Met Office Hadley Centre, HadGEM2-ES, when it was qualitatively compared with observational data (ERA Interim Model) of the campaign period and reanalysis data.

https://doi.org/10.5028/jatm.v9i1.649 836 downloads

12.

Ki-67 protein predicts survival in oral squamous carcinoma cells: an immunohistochemical study
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LOPES, Verena Karla Monteiro

; JESUS, Adriana Souza de

; SOUZA, Lucas Lacerda de

; MIYAHARA, Ligia Akiko Ninokata

; GUIMARÃES, Douglas Magno

; PONTES, Helder Antônio Rebelo

; PONTES, Flavia Sirotheau Correa

; CARVALHO, Pedro Luiz de

Brazilian Oral Research

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2017, Volume 31 elocation e66

Abstract: En | Text: En | PDF: En

Abstract The aim of this study was to identify the expression of Ki-67 and MCM3 in oral squamous cell carcinoma (OSCC) as well as to address the correlation with patient survival and clinical features. Samples were collected from 51 patients with OSCC who presented for follow-up. Immunohistochemical expression of Ki-67 and MCM3 in all groups was performed. The scoring system was previous published by Tsurutani in 2005. We used Kappa index to evaluate observers agreement degree. The associations between protein expression and clinical variables were examined for statistical significance using the chi-squared test. The overall survival rates were estimated by the Kaplan-Meier method and the relationship between protein expression and survival was compared using the log-rank test (p < 0.05). The overall survival time for a patient with positive immunostaining for Ki-67 is shorter than for a patient with negative immunostaining, (log-rank test, p = 0.00882). Patients with tumor size T3 and T4 showed a statistically significant relationship with Ki-67 immunoexpression (log-rank test, p = 0.0174). The relationship between Ki-67 expression and the relation between age, gender, smoking, tumor site, lymph node metastasis and disease stage was not significant. The examiners agreement degree by Kappa presented p value < 0.05. There was not a significant correlation when we evaluated MCM3 expression regarding clinical characteristics and survival rate. From these results, the present study suggests that positive Ki-67 expression found in OSCC patients may contribute to predict the survival in OSCC samples, as well as the relation between the protein and the tumor size.

https://doi.org/10.1590/1807-3107bor-2017.vol31.0066 1924 downloads

13.

Exposição ao benzeno em postos de combustíveis: estratégia de ações integradas de Vigilância em Saúde do Trabalhador na região dos Vales/RS
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Skamvetsakis, Adriana

; Santi, Rosemari

; Rocha, Luiz Henrique Paim da

; Brettas, Fabiane Zardo

; Fagundes, Patrícia de Souza

; Moura-Correa, Maria Juliana

Revista Brasileira de Saúde Ocupacional

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2017, Volume 42 Suppl. 1 elocation e12s

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: O benzeno é uma importante fonte de contaminação ambiental e está presente na composição da gasolina, expondo trabalhadores de Postos de Revenda de Combustíveis (PRC) a intoxicações. Objetivo: relatar experiências de vigilância da exposição ao benzeno do Centro de Referência em Saúde do Trabalhador da região dos Vales/RS. Métodos: a vigilância no território incluiu o mapeamento regional dos PRC, ações intrasetoriais, intersetoriais e interinstitucionais, inspeção nos locais de trabalho, desenvolvimento de instrumento de intervenção específico para esse ramo produtivo - Notificação Recomendatória, avaliações individuais dos trabalhadores - e outras abordagens visando intervir nos ambientes com exposição ao benzeno. Resultados: foram observadas alterações em biomarcadores de efeito e de exposição, além de inadequações dos PRC no monitoramento clínico e laboratorial dos trabalhadores. Nos ambientes e processos de trabalho ficaram evidentes situações que ampliam a exposição: inadequações nas pistas de abastecimento, uso de “flanela”, inexistência ou insuficiência de medidas de proteção coletivas, ausência de medição eletrônica dos tanques e de higienização dos uniformes por parte das empresas, dentre outras. Conclusão: as experiências desencadeadas por meio de ações integradas no setor saúde demonstraram a potencialidade benéfica da vigilância da exposição ao benzeno em PRC.

Abstract Introduction: Benzene is an important source of environmental and occupational contamination and may cause poisoning to gas station workers. Objective: to report the benzene exposure surveillance experience carried out by the Centro de Referência em Saúde do Trabalhador (Occupational Health Reference Center) of Região dos Vales, in Rio Grande do Sul, Brazil. Methods: surveillance activities included regional mapping of gas stations, intrasectoral, intersectoral and inter-institutional actions, workplace inspections, development of a specific interventional instrument for this productive branch, and other approaches aiming to intervene in benzene exposure environments. Results: we observed alterations in biomarkers of effect and of exposure, besides companies inadequacies in clinical and laboratory monitoring of workers. In the work processes and the work environments inspected, situations that enlarged exposure were evident: inadequacies in fuel supply lanes, use of cloth strip for fuel leakage absorbance during tank filling, lack or shortage of collective protection measures, absence of volume electronic measurement of the storage tanks and absence of work cloths washing by the companies, among others. Conclusion: experiences unleashed through integrated actions in the health sector demonstrated the beneficial potentiality of the benzene exposure surveillance in gas stations.

https://doi.org/10.1590/2317-6369000126015 4662 downloads

14.

Drying kinetics and microbiological quality of green onions
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Martinazzo, Ana Paula

; Correa Filho, Luiz Carlos

; Teodoro, Carlos Eduardo de Souza

; Berbert, Pedro Amorim

Revista Ceres

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dec 2016, Volume 63 N. 6 Pages 769 - 774

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO A cebolinha (Allium fistulosum L.) possui amplo consumo e comercialização no Brasil como condimento. Devido à alta produtividade na região de Volta Redonda/RJ e a alternativa da aplicação do processo de secagem como método de conservação para o excesso da produção, o objetivo do presente trabalho foi avaliar o processo de secagem de folhas de cebolinha, levando em consideração a qualidade microbiológica vegetal, assim como realizar a modelagem matemática do processo. Para predizer o fenômeno, foram utilizados modelos matemáticos utilizados para representação da secagem de produtos agrícolas. A equação de Page Modificada foi a que melhor se ajustou aos dados observados. A qualidade microbiológica das plantas foi avaliada por meio de análises de bactérias aeróbias mesófilas, bolores e leveduras. A temperatura de 60 oC foi a mais indicada para a desidratação da cebolinha, resultando em um produto com qualidade microbiológica assegurada.

ABSTRACT Green onion (Allium fistulosum L.) is widely consumed and traded in Brazil as condiment. Because of the high yields in the region of Volta Redonda - RJ and the alternative of drying as a method for preserving the excess production, the objective of this study was to evaluate the drying process of green onions, considering the microbiological quality, and to develop the mathematical modeling of this process. Mathematical models to describe the drying of agricultural products were used to predict the phenomenon. The modified Page equation gave the best fit to the data. Microbiological quality was evaluated using the analysis of aerobic mesophilic bacteria, molds and yeasts. Dehydration at 60 ºC was the most indicated for green onions, with assured microbiological quality.

https://doi.org/10.1590/0034-737x201663060004 1326 downloads

15.

Spontaneous and experimental poisoning of cattle by Palicourea aeneofusca in the region of Pernambuco and induction of conditioned food aversion
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Brito, Luiz Bezerra de

; Albuquerque, Raquel Feitosa

; Rocha, Brena Pessoa

; Albuquerque, Samuel Salgado

; Lee, Stephen Tomas

; Medeiros, Rosane Maria Trindade

; Riet-Correa, Franklin

; Mendonça, Fábio de Souza

Ciência Rural

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jan 2016, Volume 46 N. 1 Pages 138 - 143

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: O objetivo deste trabalho foi descrever os aspectos epidemiológicos, clínicos e patológicos da intoxicação por Palicourea aeneofusca em bovinos, no Agreste de Pernambuco, e comprovar se é possível induzir aversão alimentar à intoxicação por P. aeneofusca em bovinos criados sob manejo extensivo. Para determinar a ocorrência da intoxicação, foram visitadas 30 propriedades em cinco municípios do Agreste de Pernambuco. Três surtos de intoxicação em bovinos foram acompanhados. Para se induzir aversão alimentar condicionada ao consumo de P. aeneofusca, 12 bovinos foram distribuídos aleatoriamente em dois grupos de seis animais cada. Os bovinos foram pesados e receberam, no cocho, folhas verdes de P. aeneofusca, na dose de 35mg kg-1 de peso corporal, para consumo espontâneo. Os bovinos do GC receberam água (1mL kg-1 de peso corporal), via sonda esofágica, após a primeira ingestão da planta, e os demais constituíram o GTA, que foram induzidos à aversão com cloreto de lítio (LiCl - 175mg kg-1 de peso corporal), via sonda esofágica. Para os bovinos do GTA, a indução de aversão a P. aeneofusca, em que se utilizou dose única de LiCl, persistiu por 12 meses. Por outro lado, os bovinos do grupo GC continuaram ingerindo a planta em todos os testes realizados, indicando a ausência de aversão. Este trabalho comprova que o condicionamento aversivo usando LiCl foi eficaz para prevenir a intoxicações por P. aeneofusca por um período de, pelo menos, 12 meses.

ABSTRACT: The objective of this study was to describe the epidemiological, clinical, and pathological aspects of Palicourea aeneofusca poisoning in cattle in the region of Pernambuco, Brazil and to determine if it is possible to induce food aversion by P. aeneofusca poisoning in cattle raised under extensive management conditions. To determine the occurrence of poisoning, 30 properties were visited in five municipalities of the region of Pernambuco. Three outbreaks of poisoning of cattle were monitored. To induce conditioned food aversion by the consumption of P. aeneofusca, 12 animals were randomly distributed into two groups of six animals each. Cattle were weighed and received green P. aeneofusca leaves in their trough at a dose of 35mg kg-1 body weight for spontaneous consumption. The control group (CG) animals received water (1ml kg-1 body weight) via a feeding tube after the first ingestion of the plant, while the other animals, constituting the aversion test group (ATG), underwent induced aversion with lithium chloride (LiCl - 175mg kg-1 body weight) via a feeding tube. For the ATG cattle, the aversion to P. aeneofusca induced by a single dose of LiCl persisted for 12 months. In contrast, the CG animals continued to consume the plant in all tests performed, indicating the absence of aversion. This study showed that aversive conditioning using LiCl was effective in preventing poisoning by P. aeneofusca for a period of at least 12 months.

https://doi.org/10.1590/0103-8478cr20150079 1858 downloads

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