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¿EXISTE LA PRUEBA ILÍCITA, LÍCITAMENTE OBTENIDA, EN EL PROCESO PENAL CHILENO?
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Robles*, Carlos Correa

; Pardo-Álvarez**, Diego

Revista chilena de derecho

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aug 2024, Volume 51 N. 2 Pages 159 - 187

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT: In German criminal procedural law, it is possible to forbid the judge to assess a certain piece of evidence regardless of whether it has been legally obtained. This institution is called in German unselbstständiges Beweisverbot. The main justification for such exclusionary rule is constitutional: the assessment of a piece of evidence could lead to a violation of the fundamental rights of the individual. This paper analyzes the independent prohibition to use evidence in German scholarship and case law in order to ask whether its constituent elements are ascertainable in Chilean criminal procedural law and whether the solution proposed at the constitutional level in German law represents a plausible alternative in Chilean constitutional law.

RESUMEN: En el derecho procesal penal alemán es admisible prohibir la valoración por el juez de un elemento probatorio con independencia de haber sido éste obtenido lícitamente. Estas son las llamadas prohibiciones de valoración de prueba independiente. La principal justificación para tales prohibiciones es constitucional: la valoración misma de un medio de prueba podría constituir una infracción a los derechos fundamentales de las personas. Este trabajo analiza las prohibiciones de valoración independientes en la doctrina y jurisprudencia alemana, con el fin de preguntarse si sus elementos constitutivos son constatables en el derecho procesal penal chileno, y si la vía de solución propuesta a nivel constitucional desde el derecho alemán representa una alternativa plausible en el derecho constitucional chileno.

https://doi.org/10.7764/r.512.6

Position statement of the Brazilian Palliative Care Academy on withdrawing and withholding life-sustaining interventions in the context of palliative care lifesustaining life sustaining
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Vidal, Edison Iglesias de Oliveira

; Ribeiro, Sabrina Correa da Costa

; Kovacs, Maria Júlia

; Máximo da Silva, Luciano

; Sacardo, Daniele Pompei

; Iglesias, Simone Brasil de Oliveira

; Silva, Josimário João da

; Neves, Cinara Carneiro

; Ribeiro, Diego Lima

; Lopes, Fernanda Gomes

Critical Care Science

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2024, Volume 36 elocation e20240021en

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O tema da suspensão e da não implementação de intervenções de suporte de vida constitui importante fonte de controvérsia entre profissionais de saúde que lidam com pacientes com doenças graves. Decisões equivocadas, tanto em termos de introdução/manutenção, como de suspensão/não introdução dessas medidas representam fonte de sofrimento evitável para pacientes, seus entes queridos e profissionais de saúde. O presente documento representa o posicionamento do Comitê de Bioética da Academia Nacional de Cuidados Paliativos sobre essa questão e estabelece sete princípios para guiar, do ponto de vista da bioética, a abordagem de situações relacionadas a tal tema no contexto dos cuidados paliativos no Brasil. O posicionamento estabelece a equivalência entre a retirada e a não implementação de intervenções de suporte de vida e a inadequação relacionada a iniciar ou manter tais medidas em contextos em que elas estejam em desacordo com os valores e os objetivos de cuidado definidos em conjunto com pacientes e seus familiares. Adicionalmente, o posicionamento distingue tratamentos fúteis em senso estrito de tratamentos potencialmente inapropriados e elucida sua implicação crucial para a adequação do processo de tomada de decisão médica nesse contexto. Finalmente, o texto aborda a questão da objeção de consciência e seus limites; determina que o compromisso ético pelo alívio do sofrimento não deve ser influenciado pela decisão por empregar ou não intervenções de suporte de vida e adverte contra o uso de linguagem que induza pacientes/familiares a acreditarem que apenas uma das opções disponíveis relacionadas à utilização ou não dessas medidas possibilitará o alívio do sofrimento. graves equivocadas introduçãomanutenção manutenção introdução/manutenção suspensãonão guiar bioética Brasil familiares Adicionalmente Finalmente limites pacientesfamiliares

ABSTRACT The issue of withrawing and withholding life-sustaining interventions is an important source of controversy among healthcare professionals caring for patients with serious illnesses. Misguided decisions, both in terms of the introduction/maintenance and the withdrawal/withholding of these measures, represent a source of avoidable suffering for patients, their loved ones, and healthcare professionals. This document represents the position statement of the Bioethics Committee of the Brazilian Palliative Care Academy on this issue and establishes seven principles to guide, from a bioethical perspective, the approach to situations related to this topic in the context of palliative care in Brazil. The position statement establishes the equivalence between the withdrawal and withholding of life-sustaining interventions and the inadequacy related to initiating or maintaining such measures in contexts where they are in disagreement with the values and care goals defined together with patients and their families. Additionally, the position statement distinguishes strictly futile treatments from potentially inappropriate treatments and elucidates their critical implications for the appropriateness of the medical decision-making process in this context. Finally, we address the issue of conscientious objection and its limits, determine that the ethical commitment to the relief of suffering should not be influenced by the decision to employ or not employ life-sustaining interventions and warn against the use of language that causes patients/families to believe that only one of the available options related to the use or nonuse of these interventions will enable the relief of suffering. lifesustaining life sustaining illnesses decisions introductionmaintenance introduction maintenance withdrawalwithholding ones guide perspective Brazil families Additionally decisionmaking making Finally limits patientsfamilies

https://doi.org/10.62675/2965-2774.20240021-en

Plantas útiles en el área rural del municipio Linares, Nuevo León
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Estrada Castillón, Andrés Eduardo

; Paz Medrano, Alexsa Fabiola

; Scott Morales, Laura Magdalena

; Cotera Correa, Mauricio

; Valdes Alameda, Renata

; González Cuéllar, Diego Axayacatl

Revista mexicana de ciencias forestales

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oct 2023, Volume 14 N. 79 Pages 237 - 265

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Se estudiaron la flora útil y los usos de las plantas del área rural de Linares, Nuevo León. Se realizaron 180 encuestas semiestructuradas en seis ejidos. Se registraron 75 familias, 194 géneros y 253 especies con uso etnobotánico. Las principales categorías de uso fueron: ornamental (105 especies), medicinal (83), alimento (6) y maderable (25), las 34 especies restantes son utilizadas como forraje, cosméticos y creencias. Cactaceae (19), Fabaceae (15), Asteraceae (15), Poaceae (15), Lamiaceae (12), Solanaceae (6), Asparagaceae (6) y Rutaceae (4) registraron el mayor número de taxa. Del total de especies identificadas, 120 son nativas y 133 exóticas. Respecto al uso medicinal, Allium sativum, Aloe vera, Echinocereus poselgeri, Equisetum laevigatum, Croton suaveolens, Mentha spicata, Litsea glaucescens y Ruta graveolens resultaron las más utilizadas. Las principales especies maderables fueron: Prosopis glandulosa, Vachellia farnesiana, Ebenopsis ebano, Havardia pallens, Quercus canbyi, Carya illinoinensis, Pinus cembroides, P. montezumae y P. teocote. Para el Factor de Consenso del Informante (FCI) las medicinales se utilizan, principalmente, para curar males de los sistemas respiratorio, circulatorio, reproductivo y digestivo. Los taxa con los valores más altos del Índice de Valor de Uso (IVU) fueron Dysphania ambrosioides, Allium cepa y A. sativum, todas con valor=1. Respecto al Índice de Fidelidad (IF, %), los mayores porcentajes correspondieron a Artemisia ludoviciana, Cymbopogon citratus y Hedeoma drummondii. La región rural de Linares posee una rica flora útil que se utiliza principalmente como ornamental, medicinal, alimenticia, forrajera y maderable.

Abstract The useful flora and uses of plants in the rural area of Linares, Nuevo León were analyzed. A total of 180 semi-structured surveys were conducted in six ejidos. 75 families, 194 genera and 253 species with ethnobotanical use were recorded. The main categories of use were: ornamental (105 species), medicinal (83), food (6) and timber (25); the remaining 34 species are used as fodder, cosmetics and beliefs. Cactaceae (19), Fabaceae (15), Asteraceae (15), Poaceae (15), Lamiaceae (12), Solanaceae (6), Asparagaceae (6), and Rutaceae (4) recorded the highest number of taxa. Of the total number of identified species, 120 are native, and 133 are exotic. As for the medicinal use, Allium sativum, Aloe vera, Echinocereus poselgeri, Equisetum laevigatum, Croton suaveolens, Mentha spicata, Litsea glaucescens and Ruta graveolens were the most widely used. The main timber species were Prosopis glandulosa, Vachellia farnesiana, Ebenopsis ebano, Havardia pallens, Quercus canbyi, Carya illinoinensis, Pinus cembroides, P. montezumae, and P. teocote. For the Informant Consensus Factor (ICF), medicinal plants are mainly used to cure ailments of the respiratory, circulatory, reproductive, and digestive systems. The taxa with the highest Use Value Index (UVI), equal to 1 in every case, were Dysphania ambrosioides, Allium cepa, and A. sativum. In regard to the Fidelity Index (FI, %), the highest percentages corresponded to Artemisia ludoviciana, Cymbopogon citratus, and Hedeoma drummondii. The Linares rural region has a rich useful flora, which is mainly used as ornamental, medicinal, food, forage and timber.

https://doi.org/10.29298/rmcf.v14i79.1353

The SISBIOTA-Diptera Brazilian Network: A long-term survey of Diptera from unexplored Brazilian Western Arc of Amazon, Cerrado, and Pantanal SISBIOTADiptera SISBIOTA Network longterm long term Amazon Cerrado
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Lamas, Carlos José Einicker

; Fachin, Diego Aguilar

; Falaschi, Rafaela Lopes

; Alcantara, Daniel Máximo Correa de

; Ale-Rocha, Rosaly

; Amorim, Dalton de Souza

; Araújo, Maíra Xavier

; Ascendino, Sharlene

; Baldassio, Letícia

; Bellodi, Carolina Ferraz

; Bravo, Freddy

; Calhau, Julia

; Capellari, Renato Soares

; Carmo-Neto, Antonio Marcelino do

; Cegolin, Bianca Melo

; Couri, Márcia Souto

; Carvalho, Claudio José Barros de

; Dios, Rodrigo de Vilhena Perez

; Falcon, Aida Vanessa Gomez

; Fusari, Livia Maria

; Garcia, Carolina de Almeida

; Gil-Azevedo, Leonardo Henrique

; Gomes, Marina Morim

; Graciolli, Gustavo

; Gudin, Filipe Macedo

; Henriques, Augusto Loureiro

; Krolow, Tiago Kütter

; Mendes, Luanna Layla

; Limeira-de-Oliveira, Francisco

; Maia, Valéria Cid

; Marinoni, Luciane

; Mello, Ramon Luciano

; Mello-Patiu, Cátia Antunes de

; Morales, Mírian Nunes

; Oliveira, Sarah Siqueira

; Patiu, Claudemir

; Proença, Barbara

; Pujol-Luz, Cristiane Vieira de Assis

; Pujol-Luz, José Roberto

; Rafael, José Albertino

; Riccardi, Paula Raile

; Rodrigues, João Paulo Vinicios

; Roque, Fabio de Oliveira

; Sallum, Maria Anice Mureb

; Santis, Marcelo Domingos de

; Santos, Charles Morphy Dias dos

; Santos, Josenilson Rodrigues dos

; Savaris, Marcoandre

; Shimabukuro, Paloma Helena Fernandes

; Silva, Vera Cristina

; Schelesky-Prado, Daniel de Castro

; Silva-Neto, Alberto Moreira da

; Camargo, Alexssandro

; Sousa, Viviane Rodrigues de

; Urso-Guimarães, Maria Virginia

; Wiedenbrug, Sofia

; Yamaguchi, Carolina

; Nihei, Silvio Shigueo

Revista Brasileira de Entomologia

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2023, Volume 67 N. 4 elocation e20230051

Abstract: En | Text: En | PDF: En

ABSTRACT The SISBIOTA-BRASIL was a three-year multimillion-dollar research program of the Brazilian government to document plants and animals in endangered/understudied areas and biomes in Brazil. Distributional patterns and the historical events that generated them are extensively unknown regarding Brazilian fauna and flora. This deficiency hinders the development of conservation policies and the understanding of evolutionary processes. Conservation decisions depend on precise knowledge of the taxonomy and geographic distribution of species. Given such a premise, we proposed to research the diversity of Diptera of the Brazilian western arc of Amazon, Cerrado, and Pantanal in the states of Mato Grosso, Mato Grosso do Sul, and Rondônia. Three important biomes of the South American continent characterize these Brazilian states: Amazon forest, Cerrado (Brazilian Savannah), and Pantanal. Besides their ecological relevance, these biomes historically lack intensive entomological surveys. Therefore, they are much underrepresented in the Brazilian natural history collections and in the scientific literature, which is further aggravated by the fact that these areas are being exponentially and rapidly converted to commercial lands. Our project involved over 90 collaborators from 24 different Brazilian institutions and one from Colombia among researchers, postdocs, graduate and undergraduate students, and technicians. We processed and analyzed nearly 300,000 specimens from ~60 families of Diptera collected with a large variety of methods in the sampled areas. Here, we provide a detailed overview of the genera and species diversity of 41 families treated. Our results point to a total of 2,130 species and 514 genera compiled and identified for the three states altogether, with an increase of 41% and 29% in the numbers of species and genera known for the three states combined, respectively. Overall, the 10 most species-rich families were Tachinidae, Cecidomyiidae, Tabanidae, Psychodidae, Sarcophagidae, Stratiomyidae, Bombyliidae, Syrphidae, Tephritidae, and Asilidae. The 10 most diverse in the number of genera were Tachinidae, Stratiomyidae, Asilidae, Mycetophilidae, Syrphidae, Tabanidae, Muscidae, Dolichopodidae, Sarcophagidae, and Chloropidae. So far, 111 scientific papers were published regarding taxonomic, phylogenetic, and biogeographical aspects of the studied families, with the description of 101 new species and three new genera. We expect that additional publications will result from this investigation because several specimens are now curated and being researched by specialists. SISBIOTABRASIL SISBIOTA BRASIL threeyear year multimilliondollar multimillion dollar endangeredunderstudied endangered understudied Brazil flora processes premise Sul Rondônia forest Savannah, Savannah , Savannah) relevance surveys Therefore literature lands 9 2 researchers postdocs students technicians 300000 300 000 300,00 60 ~6 Here 4 treated 2130 130 2,13 51 altogether 29 combined respectively Overall 1 speciesrich rich Tachinidae Cecidomyiidae Tabanidae Psychodidae Sarcophagidae Stratiomyidae Bombyliidae Syrphidae Tephritidae Asilidae Mycetophilidae Muscidae Dolichopodidae Chloropidae far 11 taxonomic phylogenetic specialists 30000 30 00 300,0 6 ~ 213 13 2,1 5 3000 3 0 300, 21 2,

https://doi.org/10.1590/1806-9665-rbent-2023-0051

Qualidade da madeira e do carvão vegetal de quatro clones de Eucalyptus com idades entre 108 e 120 meses 10 12 1
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Ramos, Diego Correa

; Carneiro, Angélica de Cássia Oliveira

; Siqueira, Humberto Fauller de

; Oliveira, Aylson Costa

; Pereira, Bárbara Luísa Corradi

Ciência Florestal

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2023, Volume 33 N. 1 elocation e48302

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Cenários de instabilidade econômica e redução do consumo de carvão vegetal, como as ocorridas em 2009 e 2016, afetam a produção deste insumo, resultando na manutenção das florestas de eucalipto e aumento da idade de corte. O objetivo deste trabalho foi avaliar a qualidade da madeira de quatro clones de Eucalyptus (clones 1, 2, 3 e 4) com idades entre 108 e 120 meses e do carvão vegetal produzido em forno retangular. Para caracterização da madeira, foram avaliadas a relação cerne/alburno, densidade básica, massa seca por hectare.ano e composição química. As carbonizações foram realizadas em forno retangular, com capacidade de 210 m³ de madeira, e determinaram-se o rendimento gravimétrico e as propriedades do carvão vegetal: densidade do carvão vegetal, granulometria e porcentagem de finos, índice de friabilidade, análise imediata, além da massa de carvão produzida por hectare.ano. Verificou-se efeito significativo dos clones na densidade básica e massa seca, com valores de 494 a 589 kg m-3 e 12,47 a 23,34 ton.ha-1, respectivamente. O rendimento médio em carvão vegetal não diferiu entre os clones e foi igual a 34,1%, enquanto o rendimento em atiço variou de 3,2% para o clone 4 a 10,7% para o clone 3. Os clones 1 e 3 apresentaram em média 65% do volume de carvão vegetal na maior faixa granulométrica (>30 mm), enquanto os clones 2 e 4 tiveram 49,5% nessa granulometria. O carvão vegetal dos quatro clones foi de média resistência e a densidade aparente variou de 356 a 458 kg.m-3, com maior valor para o clone 3. Os clones 1 e 2 apresentaram a maior produção de carvão vegetal, 7,5 toneladas por hectare.ano. O carbono fixo não variou entre os clones, apresentando média igual a 76,92%. Os clones de Eucalyptus nas idades de 108 e 120 meses apresentam propriedades da madeira adequadas para a produção de carvão vegetal, alcançando rendimento gravimétrico e qualidade satisfatórios para uso metalúrgico, destacando-se os clones 1 (híbrido de E. urophylla x E. grandis) e 3 (híbrido de E. urophylla x E. camaldulensis). 200 2016 insumo corte 10 12 retangular cernealburno cerne alburno cerne/alburno hectareano hectare ano química 21 m determinaramse determinaram se finos friabilidade imediata Verificouse Verificou 49 58 m3 m- 1247 47 12,4 2334 23 34 23,3 ton.ha1, tonha1 tonha ton.ha ton ha ton.ha-1 respectivamente 341 34,1% 32 3,2 107 7 10,7 65 >30 30 (>3 mm, mm , mm) 495 5 49,5 35 45 kg.m3, kgm3 kgm kg.m 3, kg.m-3 75 7, 7692 76 92 76,92% metalúrgico destacandose destacando híbrido E grandis camaldulensis. camaldulensis . camaldulensis) 20 201 124 12, 233 23, ha1 ton.ha1 ton.ha- 34,1 10, 6 >3 (> 49, kg.m3 kg.m- 769 9 76,92 34, > ( 76,9 76,

ABSTRACT Economic instability scenarios and reduction in charcoal consumption, such as those that occurred in 2009 and 2016, affect production and result in the maintenance of eucalyptus forests and an increase in the rotation age. The objective of this work was to evaluate the quality of wood from four Eucalyptus clones (clones 1, 2, 3, and 4) at the ages of 108 and 120 months and the charcoal produced in a rectangular kiln. We evaluated the heart/sapwood ratio, basic density, dry mass per hectare.year, and chemical composition . The carbonizations were performed in a rectangular kiln (210 m³ of wood). We determined the gravimetric yield and the charcoal properties: density, particle size and percentage of fines, friability index, proximate analysis, and mass of charcoal produced per hectare.year. We verified the significant effect of clones on basic density and dry mass, whose variations were from 494 to 589 kg m-3 and 12.47 to 23.34 ton.ha-1, respectively. The charcoal yield did not differ among clones (34.1%), while the yield of semicarbonized wood varied from 3.2% (clone 4) to 10.7% (clone 3). The particle size of 65% of the charcoal volume of clones 1 and 3 was greater than 30 mm, and 49.5% of clones 2 and 4. We found medium mechanical resistance for charcoal from all four clones. The apparent density ranged from 356 to 458 kg.m-3, with the highest average value for clone 3. We found the highest charcoal production for clones 1 and 2, 7.5 tons per hectare.year. The fixed carbon did not vary among clones (76.92%). The wood properties of the Eucalyptus clones at ages 108 and 120 months are suitable for charcoal production for metallurgical use. Clones 1 (a hybrid of E. urophylla x E. grandis) and 3 (a hybrid of E. urophylla x E. camaldulensis) stood out from the others. consumption 200 2016 age 4 10 12 heartsapwood heart sapwood ratio hectareyear hectare year hectare.year 210 (21 m wood. wood) fines index analysis 49 58 m3 m- 1247 47 12.4 2334 23 34 23.3 ton.ha1, tonha1 tonha ton.ha ton ha ton.ha-1 respectively 34.1%, 341 34.1% , (34.1%) 32 3.2 107 7 10.7 3) 65 mm 495 5 49.5 35 45 kg.m3, kgm3 kgm kg.m kg.m-3 75 7. 76.92%. 7692 76.92% 76 92 (76.92%) use E grandis camaldulensis others 20 201 21 (2 124 12. 233 23. ha1 ton.ha1 ton.ha- 34.1 (34.1% 10. 6 49. kg.m3 kg.m- 769 76.92 9 (76.92% ( 34. (34.1 76.9 (76.92 (34. 76. (76.9 (34 (76. (3 (76 (7

https://doi.org/10.5902/1980509848302

Shear in reinforced concrete beams with continuous internal transverse reinforcement
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Souza, Diego Ferreira de

; Abrantes, Jedson Henryque Correa

; Tapajós, Luamim Sales

; Ferreira, Mauricio de Pina

; Lima Neto, Aarão Ferreira

Revista IBRACON de Estruturas e Materiais

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2023, Volume 16 N. 1 elocation e16106

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo: Elementos de concreto armado com elevada taxa de armadura longitudinal e transversal podem apresentar conflitos das duas armaduras gerando redução em produtividade durante a armação do elemento e mal posicionamento da armadura transversal diminuindo a efetividade da armadura. Diante disso, essa pesquisa apresenta um tipo de armadura transversal interna como forma de mitigar esse conflito entre as barras transversais e longitudinais. Foram ensaiadas 5 vigas faixa de concreto armado, sendo uma de referência com estribos fechados e as outras 4 com estribos internos variando a inclinação das armaduras transversais internas em 60º e 90º e a quantidade de pernas verticais da armadura transversal interna utilizada. Comparando os resultados das vigas com estribos interno com a viga de referência, observou-se que os estribos internos garantiram ganhos de até 14% de capacidade de resistência ao cisalhamento em comparação com o estribo fechado.

Abstract: Reinforced concrete elements with a high longitudinal and transverse reinforcement ratio may present conflicts on both of them, resulting in reduced labor productivity and a poor job when assembling the transversal reinforcement, reducing its effectiveness. Thus, this research presents a type of internal transverse reinforcement as an alternative to mitigate this conflict between the transverse and longitudinal bars. A total of 5 reinforced concrete wide beams were made, one of them as a reference with closed stirrups, and the other ones with internal stirrups, varying the inclination of the internal transverse reinforcement in 60° and 90°, and the number of vertical legs of the internal transverse reinforcement used. Comparing the results of the beams with internal stirrups with the reference beam, it was observed that the internal stirrups provided increases of up to 14% in shear strength when compared with the closed stirrup.

https://doi.org/10.1590/s1983-41952023000100006

Disseminated intravascular coagulation phenotype is regulated by the TRPM7 channel during sepsis
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Jiménez-Dinamarca, Ivanka

; Prado, Yolanda

; Tapia, Pablo

; Gatica, Sebastian

; Alt, Clemens

; Lin, Charles P.

; Reyes-Martínez, Cristian

; Feijóo, Carmen G.

; Aravena, Cristobal

; González-Canacer, Alejandra

; Correa, Simón

; Varela, Diego

; Cabello-Verrugio, Claudio

; Simon, Felipe

Biological Research

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2023, Volume 56 elocation 8

Abstract: En | Text: En | PDF: En

Abstract Background Sepsis is an uncontrolled inflammatory response against a systemic infection that results in elevated mortality, mainly induced by bacterial products known as endotoxins, producing endotoxemia. Disseminated intravascular coagulation (DIC) is frequently observed in septic patients and is associated with organ failure and death. Sepsis activates endothelial cells (ECs), promoting a prothrombotic phenotype contributing to DIC. Ion channel mediated calcium permeability participates in coagulation. The transient reception potential melastatin 7 (TRPM7) non-selective divalent cation channel that also contains an α-kinase domain, which is permeable to divalent cations including Ca2+, regulates endotoxin-stimulated calcium permeability in ECs and is associated with increased mortality in septic patients. However, whether endothelial TRPM7 mediates endotoxemia-induced coagulation is not known. Therefore, our aim was to examine if TRPM7 mediates coagulation during endotoxemia. Results The results showed that TRPM7 regulated endotoxin-induced platelet and neutrophil adhesion to ECs, dependent on the TRPM7 ion channel activity and by the α-kinase function. Endotoxic animals showed that TRPM7 mediated neutrophil rolling on blood vessels and intravascular coagulation. TRPM7 mediated the increased expression of the adhesion proteins, von Willebrand factor (vWF), intercellular adhesion molecule 1 (ICAM-1), and P-selectin, which were also mediated by the TRPM7 α-kinase function. Notably, endotoxin-induced expression of vWF, ICAM-1 and P-selectin were required for endotoxin-induced platelet and neutrophil adhesion to ECs. Endotoxemic rats showed increased endothelial TRPM7 expression associated with a procoagulant phenotype, liver and kidney dysfunction, increased death events and an increased relative risk of death. Interestingly, circulating ECs (CECs) from septic shock patients (SSPs) showed increased TRPM7 expression associated with increased DIC scores and decreased survival times. Additionally, SSPs with a high expression of TRPM7 in CECs showed increased mortality and relative risk of death. Notably, CECs from SSPs showed significant results from the AUROC analyses for predicting mortality in SSPs that were better than the Acute Physiology and Chronic Health Evaluation II (APACHE II) and the Sequential Organ Failure Assessment (SOFA) scores. Conclusions Our study demonstrates that sepsis-induced DIC is mediated by TRPM7 in ECs. TRPM7 ion channel activity and α-kinase function are required by DIC-mediated sepsis-induced organ dysfunction and its expression are associated with increased mortality during sepsis. TRPM7 appears as a new prognostic biomarker to predict mortality associated to DIC in SSPs, and as a novel target for drug development against DIC during infectious inflammatory diseases.

https://doi.org/10.1186/s40659-023-00419-4

Correction: Disseminated intravascular coagulation phenotype is regulated by the TRPM7 channel during sepsis
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Jiménez-Dinamarca, Ivanka

; Prado, Yolanda

; Tapia, Pablo

; Gatica, Sebastian

; Alt, Clemens

; Lin, Charles P.

; Reyes-Martínez, Cristian

; Feijóo, Carmen G.

; Aravena, Cristobal

; González-Canacer, Alejandra

; Correa, Simón

; Varela, Diego

; Cabello-Verrugio, Claudio

; Simon, Felipe

Biological Research

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2023, Volume 56 elocation 24

Abstract: En | Text: En | PDF: En

https://doi.org/10.1186/s40659-023-00433-6

Neurofibromatosis tipo 1 y manifestación en el Territorio Maxilofacial: Reporte de un caso y Revisión de la Literatura
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Bustamante-Correa, Diego

; Perez-Lagos, Luis

; Lillo-Valdés, Felipe

; Fernandez-Toro, María de los Ángeles

; Donoso-Hofer, Francisca

International journal of interdisciplinary dentistry

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dec 2022, Volume 15 N. 3 Pages 211 - 214

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT: Introduction: Neurofibroma is a benign tumor that compromises the neural sheath of nerve tissue, intimately associated with Neurofibromatosis. Due to the involvement of peripheral and/or central nerves, its clinical expression is wide as a result of compression and/or displacement of neighboring structures, making its diagnosis difficult. Objective: The aim of this article is to review the literature on Neurofibromatosis and its manifestations in the maxillofacial territory, along with the presentation of a case of mandibular Hyperchondylism associated with a neurofibroma in the temporomandibular joint region in a patient with a history of Neurofibromatosis. Methods: We present the case of a patient with laterogenesis and a history of Neurofibromatosis type I (NF1). By imaging study, a right Hyperchondylism is detected along with the presence of a radiolucent area related to the neck of the compromised condyle, whose histopathological result confirmed the diagnosis of neurofibroma. Conclusions: There is a diverse clinical picture in patients with NF1, presenting a pre-disposition to neurofibromas development and bone abnormalities, leading to the compromise of the maxillofacial territory and causing facial asymmetries. Because of this, it is essential to have knowledge and consideration of both pathologies for the right planning of patient treatment.

RESUMEN: Introducción: El neurofibroma corresponde a un tumor benigno que compromete la vaina neural del tejido nervioso, asociándose íntimamente a la neurofibromatosis. Debido al compromiso de nervios periféricos y/o centrales, su expresión clínica es muy variada producto de la compresión y/o desplazamiento de estructuras vecinas dificultando así su diagnóstico. Objetivo: El objetivo de este artículo, es el de realizar una revisión de la literatura en relación con la neurofibromatosis y sus manifestaciones en el territorio máxilofacial en conjunto con la presentación de un caso de hipercondilismo mandibular asociado a un neurofibroma en la región de la articulación temporomandibular en un paciente con antecedentes de neurofibromatosis. Métodos: Se presenta el caso de un paciente con laterognasia y antecedentes de Neurofibromatosis tipo I (NF1). Por medio de estudio imagenológico, se confirma Hipercondilismo derecho y presencia de una zona radiolúcida relacionada con el cuello del cóndilo comprometido, cuyo resultado histopatológico confirmo el diagnóstico de neurofibroma. Conclusiones: Existe una muy variada clínica en pacientes con NF1, presentando una predisposición a la formación de neurofibromas y alteraciones oseas que pudiesen comprometer el territorio máxilofacial y causar asimetrías faciales. Debido a esto, resulta imprescindible tener conocimiento y consideración de ambas patologías para una correcta planificación del tratamiento de los pacientes.

10.

Plant, bird, and mammal diversity of the Tomogrande field station, Vichada, Colombia
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Estrada-Villegas, Sergio

; Rivas, Luz Dary

; Barrera, John Fredy

; Barrera Rivas, Steven

; Correa, Diego F

; Argüello Bernal, Laura Sofía

; Aldana, Ana María

; Casa, Luisa Fernanda

; Lozano-Balcázar, Alejandro

; Gómez-Bahamón, Valentina

; Gómez, Camila

; Bayly, Nicholas

; Jahn, Alex E

; Quiñones, Antonio

; Corbett, Eamon C

; Castro, Francisco

; Stevenson, Pablo

Biota colombiana

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dec 2022, Volume 23 N. 2 elocation e1027

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen La Altillanura es un ecosistema único de los Llanos colombianos, caracterizado por sabanas bien drenadas y grandes extensiones de bosques ribereños. La Altillanura alberga ricas comunidades poco estudiadas y actualmente amenazadas por la agroindustria a gran escala y no planificada. Además, el número de áreas protegidas públicas en la Altillanura no es suficiente para conservar los hábitats y especies amenazados. Por lo tanto, los esfuerzos de las reservas privadas son cruciales para la conservación de la biodiversidad de la región. Presentamos el primer listado de especies del Tomogrande, reserva natural privada y estación de investigación científica en el municipio de Santa Rosalía, Vichada, Colombia. Después de diez años de investigación en curso, hemos registrado 299 especies de plantas, 189 especies de aves y 47 especies de mamíferos. En comparación con otras reservas naturales privadas en Vichada y con el Parque Nacional Tuparro, el área protegida más grande de la región, Tomogrande hace una contribución sustancial a la conservación de los tres grupos taxonómicos. Abogamos por una mejor planificación del paisaje y que prácticas sostenibles sean obligatorias en la Altillanura, a fin de proteger su biodiversidad y los medios de vida de todos los actores que habitan esta región.

Abstract The Altillanura is a unique ecosystem within the Colombian Llanos, characterized by well-drained savannas and extensive riparian forests. The Altillanura harbors a rich assemblage of species, largely understudied and currently under threat by large-scale and unplanned agribusiness. Moreover, the number of public protected areas in the Colombian Llanos, particularly in the Altillanura, is insufficient to conserve the threatened habitats and species. Therefore, conservation efforts by private reserves are crucial for the protection of the region’s biodiversity. Here we present the first species list of the Tomogrande, a private nature reserve and scientific research field station in the municipality of Santa Rosalía, Vichada, Colombia. After ten years of ongoing research, we have recorded 299 species of plants, 189 species of birds, and 47 species of mammals. Compared to other private nature reserves in Vichada and the Tuparro National Park, the largest protected area in the region, Tomogrande makes a substantial contribution to the conservation of all three taxonomic groups. We advocate that better landscape planning and sustainable practices should become mandatory in the Altillanura to protect its biodiversity and the livelihoods of all stakeholders that inhabit this region.

https://doi.org/10.21068/2539200x.1027

11.

Redefinición, correlación e implicaciones geotectónicas del batolito de Ibagué, Colombia
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Rodríguez-García, Gabriel

; Ramírez, Diego Armando

; Zapata, Juan Pablo

; Correa-Martínez, Ana María

; Sabrica, Carlos

; Obando, Gloria

Boletín de Geología

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dec 2022, Volume 44 N. 3 Pages 65 - 93

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Nuevos datos de campo, petrografía, geoquímica y geocronología U-Pb en circón permiten redefinir el batolito de Ibagué y proponer nuevas unidades. El batolito de Ibagué, al norte de la Falla de Ibagué, ha sido dividido en la Metatonalita de Anzoátegui (~194,7 km2) y la Tonalita de Ibagué (-278 km2). Al sur de la falla de Ibagué conserva el nombre de batolito de Ibagué con una extensión de ~3200 km2, debido a la escisión de los gabros de Belalcázar y Los Guayabos de edad Carbonífera, los granitos de Ortega y La Plata de edad Pérmica, y la Cuarzomonzodiorita de Páez de edad Jurásico temprano. La Metatonalita de Anzoátegui y la Tonalita de Ibagué se componen de metatonalitas, tonalitas y granodioritas calco-alcalinas metaluminosas, con edades U-Pb para la Metatonalita de Anzoátegui entre 158,2+1,2/-0,4 y 150,17±0,86 Ma y para la Tonalita de Ibagué entre 145,71+0,72/-1,42 Ma y 138,48±0,95 Ma, Jurásico medio a Cretácico inferior. El batolito de Ibagué está constituido por tonalitas, granodioritas y monzogranitos calco-alcalinos a calco-alcalinos de alto K, metaluminosos y peraluminosos, con edades entre 171,5±1,3 y 137,9±1,0 Ma. El batolito de Ibagué, la Metatonalita de Anzoátegui y la Tonalita de Ibagué son granitoides cálcicos de arco, con anomalías negativas de Nb, Ti y P. La posición geotectónica, la composición petrográfica y química, y las edades de cristalización permitieron correlacionar el batolito de Ibagué, La Metatonalita de Anzoátegui y la Tonalita de Ibagué con los batolitos de Segovia y Los Alisales, la Granodiorita de Siapana, el stock de Payandé, y con unidades volcánicas como el Volcánico de La Malena, las Vulcanitas de Segovia y Chaparral. Con esta correlación se separan unidades que estaban asociadas al batolito de Ibagué que afloran en una posición más oriental, definidas como los cinturones de plutones del carbonífero, Pérmico y Jurásico temprano a medio.

Abstract New fieldwork, pétrographie, geochemical, and zircon U-Pb geochronologic data allow us to identify new units and redefine the limits of the Ibagué batholith. The Ibagué batholith, located to the north of the Ibagué Fault, was divided into two geological units: the Anzoátegui Metatonalite (~194.7 km2) and Ibagué Tonalité (~278 km2). To the south of the Ibagué fault, the name Ibagué batholith is maintained, but its original extension changes to ~3200 km2 due to theoccurrence of the Carboniferous Belalcázar and Los Guayabos gabbros, the Permian Ortega and La Plata granites, and the early Jurassic Páez quartz-monzodiorite. The Anzoátegui Metatonalite and Ibagué Tonalite are composed of calc-alkaline and metaluminous metatonalites, tonalites, and granodiorites, yielding U-Pb crystallization ages between 158.2+1.2/-0.4 and 150.17±0.86 Ma, and between 145.71+0.72/-1.42 Ma and 138.48±0.95 Ma, respectively. The Ibagué batholith is constituted by calc-alkaline to high K calc-alkaline, metaluminous and peraluminous, tonalites, granodiorites, and monzogranites, yielding crystallization ages between 171.5±1.3 and 137.9±1.0 Ma. The Ibagué batholith, the Anzoátegui Metatonalite, and the Ibagué Tonalite are calcic granitoids generated in an arc environment, presenting Nb, Ti, and P negative anomalies. The geotectonic position, petrographic and geochemical composition, and crystallization ages allowed us to correlate the Ibagué batholith, the Anzoátegui Metatonalite, and the Ibagué Tonalite with the Segovia and Los Alisales batholiths, the Siapana granodiorite, the Payandé stock, and volcanic units such as the La Malena volcanic rocks, the Segovia and Chaparral vulcanites. This correlation also drives the separation of the Ibagué batolith from other units like the Carboniferous, Permian, and Early to Middle Jurassic plutons cropping out further east.

https://doi.org/10.18273/revbol.v44n3-2022003

12.

Estudiar en la Universidad y tener hijos e hijas: Desafíos de la adultez emergente
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Portilla-Saavedra, Diego

; Cruz-Riveros, Consuelo

; Correa, Felipe Ponce

; Gallardo-Peralta, Lorena

Psicoperspectivas

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jul 2022, Volume 21 N. 2 Pages 67 - 78

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Although emerging adulthood and the college population have been extensively studied in the literature, little research has focused on measures of stress, subjective well-being, and social support in young people who have children in addition to being college students. The transitions of emerging adulthood are especially significant when one is both a college student and a parent. The aim of this article was to analyze stress, subjective well-being (life satisfaction and affectivity) and social support in university students with or without children in northern Chile. The sample consisted of N = 625 university students aged 18 to 25 years. A binary logistic regression model was used to analyze the variables and the dichotomous category of having or not having children. It was concluded that, despite the fact that university students with children presented stress indexes in a significant range, they also maintained a positive affectivity, and it seems that this characteristic helps them to face the convergence between higher education and parenthood.

Resumen Pese a que la adultez emergente y la población universitaria ha sido ampliamente estudiadas en la literatura, son escasas las investigaciones que enfatizan en medidas de estrés, bienestar subjetivo y apoyo social en las/os jóvenes que además de ser universitarios/as, tienen hijos/as. Las transiciones de la adultez emergente son especialmente considerables cuando se es universitario/a y madre o padre a la vez. El objetivo de este artículo fue analizar el estrés, el bienestar subjetivo (satisfacción con la vida y afectividad) y el apoyo social en universitarios/as con hijos/as o sin hijos/as del norte de Chile. Integraron la muestra N = 625 estudiantes universitarios/as de edades entre 18 a 25 años. Se utilizó un modelo de regresión logística binaria, con el objetivo de analizar las variables y la categoría dicotómica de tener o no tener hijos/as. Se concluye que, pese a que las/os universitarias/os con hijos/as presentaron índices de estrés en un rango significativo, de igual forma mantienen una afectividad positiva, pareciendo que esta característica ayuda a enfrentar la convergencia entre cursar estudios superiores y ser padre o madre.

https://doi.org/10.5027/psicoperspectivas-vol21-issue2-fulltext-2295 146 downloads

13.

Glosoplastía con Técnica de Harada, en un Paciente con Macroglosia por Amiloidosis
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Reyne-Silva, Nicolás

; Moris-Vidal, Hilda

; Bustamante-Correa, Diego

; Astorga-Mori, Felipe

International journal of odontostomatology

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mar 2022, Volume 16 N. 1 Pages 19 - 22

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT: Macroglossia corresponds to a condition characterized by an increase in lingual size, which can cause aesthetic and functional alterations, even compromising the airway. It is one of the early manifestations of amyloidosis, which is associated with some cases of Multiple Myeloma. Presented a clinical case of a 73-year-old male patient, presenting macroglossia in the Maxillofacial Surgery service of the Hospital del Carmen Maipú, Santiago de Chile, where it was determined that the macroglossia was in the context of amyloidosis. The diagnosis and surgical treatment performed is described, as a complication characterized by airway obstruction requiring Glossoplasty using the Harada technique.

RESUMEN: La Macroglosia, corresponde a un cuadro caracterizado por un aumento de tamaño lingual, pudiendo causar alteraciones estéticas y funcionales, llegando incluso a comprometer la vía aérea. Es una de las manifestaciones temprana de la amiloidosis, que a su vez se encuentra asociada a algunos casos de Mieloma Múltiple. Se presenta caso clínico de paciente sexo masculino de 73 años de edad, que presenta macroglosia en servicio de Cirugía Maxilofacial del Hospital del Carmen Maipú, Santiago de Chile. Donde se determinó que la macroglosia estaba en contexto de una amiloidosis, se describe diagnóstico y tratamiento quirúrgico realizado, además de complicación caracterizada por obstrucción de vía aérea, requiriendo Glosoplastía mediante técnica de Harada.

8 downloads

14.

Recommendations for the diagnosis and management of persons with suspected vaccine-induced immune thrombotic thrombocytopenia (VITT)
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Yomayusa, Nancy

; Acevedo, Juan

; Virginia, Abello Polo

; Izaguirre, Raúl

; Ramírez, Carlos

; Solano, María Helena

; Ramírez, Sergio

; Rodríguez, Patricia

; Morón, Lina

; De la Hoz, Ilich

; Chacón, Kelly Rocio

; Gutiérrez, Paula

; Agudelo, Claudia

; Hernández, Sonia

; León, Guillermo

; Accini, José

; Ortíz, Guillermo

; Concha-Mejia, Alejandro

; Contreras, Rubén

; Escobar, Bibiana

; Espinosa, Tatiana

; González, Camilo

; Yama, Erica

; Aroca, Gustavo

; Guillermo, Cecilia

; Hamann, Otto

; Horlandy, Laura

; Moreno, Claudia

; Mejía, Natalia

; Mendoza, Fernán

; Castellanos, Jeffrey

; Rozo, Jose

; Montero, Camilo

; Navarro, José

; Oñate, José

; Pinto, Diego

; Restrepo, Natalia

; Saenz, Oscar

; Triana, Lina

; Correa, Liliana

; Sabbagh, Luis

; Castillo, Ana

; Torres, Rodolfo

; Lineros, Alberto

Infectio

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mar 2022, Volume 26 N. 1 Pages 3 - 10

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen En meses recientes se han reportado casos raros de trombocitopenia y trombosis en sitios inusuales, que ocurren dentro de una ventana de riesgo típica ( por ejemplo de 4 a 28 días) luego de recibir vacunas de SARS CoV 2. Los profesionales de la salud deben estar preparados para detectar estos casos a tiempo. Un panel de expertos y una red de transferencia de conocimiento realizó una búsqueda libre de literatura seleccionada. Con la información disponible y la experticia clínica del grupo de trabajo revisamos y dimos recomendaciones para la sospecha temprana, el diagnostico (definición de caso, el uso de pruebas de laboratorio especificas y de imágenes diagnósticas) para le manejo de estas condiciones tromboticas. Este documento es considerado un documento vivo que debe ser actualizado a medida que surja nueva evidencia y las recomendaciones vayan cambiando con el tiempo

Abstract In recent months, rare cases of thrombosis at unusual sites associated with thrombocytopenia, occurring within a typical risk window (i.e., 4-28 days) after receiving SARS CoV2 vaccines, have been reported. Healthcare professionals should be prepared to detect these cases on time. The Expert Panel of the Knowledge Management and Transfer Network conducted a free search of the related literature. With the available information and the clinical expertise of the working group, we formulated, reviewed, and endorsed recommendations for the timely suspicion, diagnosis (case definitions, the use of initial laboratory and imaging tests, specific tests), and management of these thrombotic conditions. This document is considered a living document that will be updated as new evidence emerges, and recommendations may change over time.

https://doi.org/10.22354/in.v26i1.987 68 downloads

15.

Physical, physiological, physicochemical and nutritional characterization of pumpkin ( Cucurbita maxima) in postharvest stage cultivated in Antioquia-Colombia
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Márquez Cardozo, Carlos Julio

; Molina Hernández, Daniela

; Caballero Gutiérrez, Birina Luz

; Ciro Velásquez, Héctor José

; Restrepo Molina, Diego Alonso

; Correa Londoño, Guillermo

Revista Facultad Nacional de Agronomía Medellín

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dec 2021, Volume 74 N. 3 Pages 9735 - 9744

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN La calabaza (Cucurbita maxima), también llamada auyama es una fruta de consumo masivo, utilizada en transformaciones agroindustriales para la obtención de nuevos productos alimenticios. Este estudio tuvo como objetivo evaluar las propiedades físicas, fisiológicas y fisicoquímica durante a un periodo de almacenamiento de 42 días y nutricionales de las fracciones del fruto recién cosechado. Para las coordenadas del color CIEL*a*b*, los valores de L* y a* tanto para la pulpa y cáscara no presentaron cambios significativos durante el tiempo de almacenamiento evaluado, pero sí presentó cambios en los valores de b* en la cáscara del fruto. Además, se observó una disminución en la firmeza-fuerza de 10,8% en el fruto con cáscara y en la pulpa de 19,8%, con una pérdida peso de fruto entero del 2,33% y una tasa de respiración promedio de 6,9 mg CO2 kg-1 h-1. De acuerdo a las características fisicoquímicas evaluadas en la pulpa del fruto, pH, porcentaje de humedad, acidez, actividad de agua y sólidos solubles totales no se presentaron cambios estadísticamente significativos durante el tiempo de almacenamiento. A nivel nutricional la auyama es una buena fuente de minerales, destacando la alta concentración de potasio en todas sus fracciones, y también en carotenoides totales (4,11 mg de β-caroteno g-1 (b.s.) en la pulpa y 6,24 mg de β-caroteno g-1 base seca (b.s.) en la cáscara). El fruto vegetal de la auyama bajo condiciones normales de almacenamiento presenta una baja tasa de respiración manteniendo sus características fisicoquímicas aptas para el consumo durante todo el periodo de evaluación, presentando condiciones adecuadas para el desarrollo de productos agroindustriales que permitan darle valor agregado durante el período de evaluación.

ABSTRACT Pumpkin (Cucurbita maxima), also called squash is a mass consumption fruit used in agro-industrial transformations to obtain new food products. This study aimed to evaluate the physical, physiological and physicochemical properties during a storage period of 42 days and the nutritional compounds of the freshly harvested fruit fractions. According to the CIEL*a*b* space, both the pulp and peel did not present significant changes in L* and a* values during the evaluated storage time; however, in the peel, a change in the b* values was evidenced. In addition, there was a decrease in the firmness of 10.8% in the fruit with peel and in the pulp, it was of 19.8% was observed, with a whole fruit weight loss of 2.33% and an average respiration rate of 6.9 mg CO2 kg-1h-1. According to physicochemical characteristics evaluated in the pulp, the values of pH, percentage of humidity, acidity, water activity and total soluble solids had no statistically significant changes occurred during the storage time. At the nutritional level, pumpkin is a good source of minerals, with a high concentration of potassium in all its fractions, and also has in total carotenoids (4.11±1.6 mg of β-carotene g-1 oven dry (o.d) in pulp and 6.24±2.7 mg of β-carotene g-1 (o.d) in peel ). It was possible to conclude that the pumpkin has a low respiration rate, maintaining its physicochemical characteristics suitable for consumption throughout the evaluation period, presenting suitable conditions.

https://doi.org/10.15446/rfnam.v74n3.90820 73 downloads

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publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

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