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au:Coelho, Luiz Otávio de Mattos

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The Role of Computed Tomography in the Diagnosis of Congenital Sensorineural Hearing Loss
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Buschle, Mauricio

; Hamerschmidt, Rogerio

; Matias, Jorge Eduardo Fouto

; Zanini, Otavio Pereira Lima

; Coelho, Luiz Otavio de Mattos

; Polanski, Jose Fernando

International Archives of Otorhinolaryngology

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sep 2024, Volume 28 N. 3 Pages 387 - 393

Abstract: En | Text: En | PDF: En

Abstract Introduction One of the paths in the investigation of congenital sensorineural hearing loss (CSNHL) is to try to characterize its etiology through the inner ear evaluation using high resolution computer tomography (CT) scans. With minor malformation, it is not always possible for a simple visual inspection to recognize if the structure in the inner ear is normal or not. Objective To verify if measurements of the inner ear are predictive of sensorineural hearing loss (SNHL) and suggest cutoff points of size limits. Methods Retrospective cross-sectional study of inner ear CT scan measurements of 214 patients, 50 with congenital SNHL (CSNHL) and 164 acquired SNHL (ASNHL) (control group). Results In the CSNHL group, central bony island (CBI) were 0.48 mm smaller (p < 0.001), cochlear nerve aperture was (CNA) 0.10 mm smaller (p < 0.001), and cochlea height was (CH) 0.15 mm smaller (p < 0.001). Vestibular aqueduct (VA) and cochlea width (CW) were similar between groups (0.70 vs 0.72, p = 0.19, and 7.20 vs 7.15 p = 0.23). The predictive cutoff points for CSNHL were CBI = 3.6 mm, CAN = 1.4 mm, CH = 3.4 mm, CW = 7.0 mm, and VA = 0.9 mm. Conclusion Congenital sensorineural hearing loss determined a decrease in CBI, opening of the cochlear nerve (OCN), and CW. Thus, these measures, at the cutoff points indicated, should make us aware of the diagnosis of congenital hearing loss. (CSNHL (CT scans malformation (SNHL limits crosssectional cross sectional 21 patients 5 16 ASNHL (ASNHL control group. group . group) (CBI 048 0 48 0.4 0.001, 0001 0.001 , 001 0.001) CNA (CNA 010 10 0.1 (CH 015 15 0.001. (VA (CW 0.70 070 70 (0.7 072 72 0.72 019 19 0.19 720 7 20 7.2 715 7.1 0.23. 023 0.23 23 0.23) 36 3 6 3. 14 1 4 1. 34 7. 09 9 0. OCN, OCN (OCN) Thus measures indicated 2 04 000 0.00 00 01 0.7 07 (0. 71 02 0.2 (OCN 0.0 (0 (

https://doi.org/10.1055/s-0044-1786827

Imaging Studies in Otosclerosis: An Up-to-date Comprehensive Review
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Mangia, Lucas Resende Lucinda

; Coelho, Luiz Otávio de Mattos

; Carvalho, Bettina

; de Oliveira, Adriana Kosma Pires

; Hamerschmidt, Rogerio

International Archives of Otorhinolaryngology

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apr 2021, Volume 25 N. 2 Pages 318 - 327

Abstract: En | Text: En | PDF: En

Abstract Introduction Otosclerosis is a primary osteodystrophy of the otic capsule, frequently responsible for acquired hearing loss in adults. Although the diagnostic value of imaging investigations in otosclerosis is debatable, they might still be employed with different goals within the context of the disease. Objectives The present paper aims to review the most recent literature on the use of imaging studies in otosclerosis for the most varied purposes, from routine application and differential diagnosis to prognostic prediction and investigation of surgical failure. Data Synthesis The diagnosis of otosclerosis is usually clinical, but computed tomography (CT) is paramount in particular cases for the differential diagnosis. The routine use, however, is not supported by strong evidence. Even so, there is growing evidence of the role of this method in surgical planning and prediction of postoperative prognosis. In specific scenarios, for example when superior semicircular canal dehiscence (SSCD) syndrome is suspected or in surgical failure, CT is crucial indeed. Magnetic resonance imaging (MRI), however, has limited - although important - indications in the management of individuals with otosclerosis, especially in the evaluation of postoperative complications and in the follow-up of medical treatment in active ostosclerosis. Conclusion Imaging studies have a broad range of well-established indications in otosclerosis. Besides, although the routine use of CT remains controversial, the most recent papers have shed light into new potential benefits of imaging prior to surgery.

https://doi.org/10.1055/s-0040-1715149 109 downloads

Diretrizes Brasileiras de Hipertensão Arterial – 2020
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Barroso, Weimar Kunz Sebba

; Rodrigues, Cibele Isaac Saad

; Bortolotto, Luiz Aparecido

; Mota-Gomes, Marco Antônio

; Brandão, Andréa Araujo

; Feitosa, Audes Diógenes de Magalhães

; Machado, Carlos Alberto

; Poli-de-Figueiredo, Carlos Eduardo

; Amodeo, Celso

; Mion Júnior, Décio

; Barbosa, Eduardo Costa Duarte

; Nobre, Fernando

; Guimarães, Isabel Cristina Britto

; Vilela-Martin, José Fernando

; Yugar-Toledo, Juan Carlos

; Magalhães, Maria Eliane Campos

; Neves, Mário Fritsch Toros

; Jardim, Paulo César Brandão Veiga

; Miranda, Roberto Dischinger

; Póvoa, Rui Manuel dos Santos

; Fuchs, Sandra C

; Alessi, Alexandre

; Lucena, Alexandre Jorge Gomes de

; Avezum, Alvaro

; Sousa, Ana Luiza Lima

; Pio-Abreu, Andrea

; Sposito, Andrei Carvalho

; Pierin, Angela Maria Geraldo

; Paiva, Annelise Machado Gomes de

; Spinelli, Antonio Carlos de Souza

; Nogueira, Armando da Rocha

; Dinamarco, Nelson

; Eibel, Bruna

; Forjaz, Cláudia Lúcia de Moraes

; Zanini, Claudia Regina de Oliveira

; Souza, Cristiane Bueno de

; Souza, Dilma do Socorro Moraes de

; Nilson, Eduardo Augusto Fernandes

; Costa, Elisa Franco de Assis

; Freitas, Elizabete Viana de

; Duarte, Elizabeth da Rosa

; Muxfeldt, Elizabeth Silaid

; Lima Júnior, Emilton

; Campana, Erika Maria Gonçalves

; Cesarino, Evandro José

; Marques, Fabiana

; Argenta, Fábio

; Consolim-Colombo, Fernanda Marciano

; Baptista, Fernanda Spadotto

; Almeida, Fernando Antonio de

; Borelli, Flávio Antonio de Oliveira

; Fuchs, Flávio Danni

; Plavnik, Frida Liane

; Salles, Gil Fernando

; Feitosa, Gilson Soares

; Silva, Giovanio Vieira da

; Guerra, Grazia Maria

; Moreno Júnior, Heitor

; Finimundi, Helius Carlos

; Back, Isabela de Carlos

; Oliveira Filho, João Bosco de

; Gemelli, João Roberto

; Mill, José Geraldo

; Ribeiro, José Marcio

; Lotaif, Leda A. Daud

; Costa, Lilian Soares da

; Magalhães, Lucélia Batista Neves Cunha

; Drager, Luciano Ferreira

; Martin, Luis Cuadrado

; Scala, Luiz César Nazário

; Almeida, Madson Q.

; Gowdak, Marcia Maria Godoy

; Klein, Marcia Regina Simas Torres

; Malachias, Marcus Vinícius Bolívar

; Kuschnir, Maria Cristina Caetano

; Pinheiro, Maria Eliete

; Borba, Mario Henrique Elesbão de

; Moreira Filho, Osni

; Passarelli Júnior, Oswaldo

; Coelho, Otavio Rizzi

; Vitorino, Priscila Valverde de Oliveira

; Ribeiro Junior, Renault Mattos

; Esporcatte, Roberto

; Franco, Roberto

; Pedrosa, Rodrigo

; Mulinari, Rogerio Andrade

; Paula, Rogério Baumgratz de

; Okawa, Rogério Toshiro Passos

; Rosa, Ronaldo Fernandes

; Amaral, Sandra Lia do

; Ferreira-Filho, Sebastião R.

; Kaiser, Sergio Emanuel

; Jardim, Thiago de Souza Veiga

; Guimarães, Vanildo

; Koch, Vera H.

; Oigman, Wille

; Nadruz, Wilson

Arquivos Brasileiros de Cardiologia

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mar 2021, Volume 116 N. 3 Pages 516 - 658

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20201238 10948 downloads

Anatomical Variations in Patients with Ménière Disease: A Tomography Study
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Lucinda, Lucas Resende

; Cristoff, Daniela Dranka

; Coelho, Luiz Otávio De Mattos

; Zanini, Otávio Pereira Lima

; Guimarães, Rita De Cassia Cassou

International Archives of Otorhinolaryngology

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jul 2018, Volume 22 N. 3 Pages 231 - 238

Abstract: En | Text: En | PDF: En

Abstract Introduction The etiology of Ménière disease (MD), a difficult-to-treat condition with great morbidity, remains controversial in the literature. The possible clinical and diagnostic impact of anatomical variations of the temporal bone among patients with MD has been recently studied. Objective To identify anatomical variations of the temporal bone associated with the diagnosis of MD. Methods Thirty-seven patients were included, although each ear was considered separately (n = 74). A case group (nA = 33) was composed of the affected ears of patients with definiteMDand a control group (nB = 41) was used consisting of the ears of individuals who did not meet the criteria for MD and of the contralateral ears from patients with unilateral disease. Tomographic images from the individuals included in the study were submitted to a blinded and systematic evaluation regarding a broad variety of anatomical variations of the temporal bone. Obtained data were compared statistically between the groups and after stratifying the study sample. Significance level was set at 0.05. Results Among the affected ears, it was observed an increased number of tomographic scans in which the vestibular aqueduct could not be identified (p = 0.01, Fisher exact test). No statistically significant differences were observed when comparing the affected and contralateral ears frompatients with unilateral MD, between affected ears from patients with unilateral and bilateral disease or between contralateral ears of patients with unilateral affection and patients without the disease. Conclusion Some anatomical variations might be more frequent in the affected ears of patients with MD, such as the lower rates of individualization of the vestibular aqueduct.

https://doi.org/10.1055/s-0037-1604463 690 downloads

Adrenoleucodistrofia ligada ao X: correlação entre o escore de Loes e parâmetros do tensor de difusão
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Ono, Sergio Eiji

; Carvalho Neto, Arnolfo de

; Gasparetto, Emerson Leandro

; Coelho, Luiz Otávio de Mattos

; Escuissato, Dante Luiz

; Bonfim, Carmem Maria Sales

; Ribeiro, Lisandro Lima

Radiologia Brasileira

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dec 2014, Volume 47 N. 6 Pages 342 - 349

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Objetivo: Avaliar a correlação dos parâmetros do tensor de difusão com o escore de Loes e se os parâmetros do tensor de difusão poderiam indicar alterações estruturais precoces. Materiais e Métodos: As medidas do tensor de difusão foram obtidas em 30 exames de 14 pacientes com adrenoleucodistrofia ligada ao X e foram correlacionadas com o escore de Loes. Um grupo controle de 28 pacientes masculinos foi avaliado para estabelecer medidas do tensor de difusão pareadas por idade. Análises estatísticas intra e interobservador foram feitas. Resultados: As medidas do tensor de difusão apresentam forte correlação com o escore de Loes segundo o coeficiente de Pearson (r), com valores de –0,86, 0,89, 0,89 e 0,84 para a fração de anisotropia e difusibilidades média, radial e axial (p < 0,01). A análise da mudança nas medidas do tensor de difusão no estágio inicial da doença indica que os valores de difusibilidades média e radial podem ajudar a predizer a progressão da doença. Conclusão: As medidas de parâmetros do tensor de difusão poderiam ser usadas como um adjunto ao escore de Loes, auxiliando no monitoramento da doença e alertando uma possível progressão do escore de Loes na faixa de interesse para decisões terapêuticas.

Objective: The present study was aimed at evaluating the correlation between diffusion tensor imaging parameters and Loes score as well as whether those parameters could indicate early structural alterations. Materials and Methods: Diffusion tensor imaging measurements were obtained in 30 studies of 14 patients with X-linked adrenoleukodystrophy and were correlated with Loes scores. A control group including 28 male patients was created to establish agematched diffusion tensor imaging measurements. Inter- and intraobserver statistical analyses were undertaken. Results: Diffusion tensor imaging measurements presented strong Pearson correlation coefficients (r) of –0.86, 0.89, 0.89 and 0.84 for fractional anisotropy and mean, radial and axial diffusivities (p < 0.01). Analysis of changes in diffusion tensor measurements at early stage of the disease indicates that mean and radial diffusivities might be useful to predict the disease progression. Conclusion: Measurements of diffusion tensor parameters can be used as an adjunct to the Loes score, aiding in the monitoring of the disease and alerting for possible Loes score progression in the range of interest for therapeutic decisions.

https://doi.org/10.1590/0100-3984.2013.1886 7624 downloads

Persistence of a hypoglossal artery: case report
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Timi, Jorge Rufino Ribas

; Coelho, Luiz Otavio de Mattos

; Pasini, Ricardo Scopel

Jornal Vascular Brasileiro

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jun 2014, Volume 13 N. 2 Pages 146 - 149

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Os autores apresentam o caso de persistência da artéria hipoglossa. A artéria hipoglossa é a segunda anastomose carótida-basilar mais comum, com frequência de 0,02% a 0,09%, podendo estar associada a doenças vasculares cerebrais. Seu diagnóstico se faz através de métodos de imagem, sendo a angiotomografia o método mais utilizado.

The authors present a case of persistent hypoglossal artery. Persistent hypoglossal artery is the second most common carotid-basilar anastomosis with a frequency of 0.02% to 0.09% and it can be associated with cerebrovascular disease. Diagnosis is by imaging methods and angiotomography is the method most often employed.

https://doi.org/10.1590/jvb.2014.061 9429 downloads

Evaluation with Doppler vascular ultrasound in postoperative endovascular treatment of abdominal aortic aneurysm: a prospective comparative study with angiotomography
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Franca, Graciliano Jose

; Baroncini, Liz Andrea Villela

; Oliveira, Aguinaldo de

; Vidal, Enrique Antonio

; Miyamotto, Marcio

; Toregeani, Jeferson Freitas

; Coelho, Luiz Otavio de Mattos

; Timi, Jorge Rufino Ribas

Jornal Vascular Brasileiro

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jun 2013, Volume 12 N. 2 Pages 102 - 109

Abstract: En | Text: En | PDF: En

BACKGROUND: Diagnosis of abdominal aortic aneurysm (AAA) is usually incidental, and surgical treatment, when indicated, may be open or endovascular. The drawbacks of computed angiotomography (CTA) and the advantages of Doppler ultrasonography have led to the development of alternative follow-up protocols, comparing the two methods. OBJECTIVE: To determine validity indices for Doppler ultrasonography and to correlate them with CTA results in a group of patients who had undergone elective endovascular treatment of AAAs. MATERIAL AND METHODS: Thirty-three patients were selected. The following three items were evaluated: 1) presence or absence of endoleak; 2) presence of blood flow in the aortoiliac segment; and 3) maximum AAA diameter. RESULTS: For the detection of endoleak, Doppler ultrasonography showed a sensitivity of 54.5%, a specificity of 92.8%, a positive predictive value of 85.7%, a negative predictive value of 92.8%, and an overall accuracy of 76%. For the evaluation of blood flow in the aortoiliac segment, values were 100, 97.8, 80, 97.8, and 98%, respectively. Maximum AAA diameter was similarly measured by both methods, with statistically significant differences (mean difference: 1.98 mm). Pearson's correlation coefficient was 0.97, showing that Doppler ultrasonography and CTA yielded similar results. CONCLUSION: Doppler ultrasonography showed good validity indices and a moderate correlation with CTA in the postoperative evaluation of patients undergoing endovascular treatment of AAAs.

https://doi.org/10.1590/S1677-54492013000200003 4249 downloads Cited 1 time in SciELO

Treatment of West syndrome with vigabatrin: Reversible MRI signal changes
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Carvalho Neto, Arnolfo de

; Coelho, Luiz Otávio de Mattos

; Ono, Sergio Eiji

; Crippa, Ana Chrystina de Souza

Arquivos de Neuro-Psiquiatria

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dec 2011, Volume 69 N. 6 Pages 998 - 998

Abstract: En | Text: En | PDF: En

4585 downloads

Bacterial pneumonia following bone marrow transplantation: HRCT findings
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Coelho, Luiz Otávio de Mattos

; Gasparetto, Taísa Davaus

; Escuissato, Dante Luiz

Jornal Brasileiro de Pneumologia

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may 2009, Volume 35 N. 5 Pages 431 - 435

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

OBJETIVO: Descrever os achados de TCAR em pacientes com pneumonia bacteriana após transplante de medula óssea (TMO). MÉTODOS: Estudo retrospectivo com 30 pacientes diagnosticados com pneumonia bacteriana, documentada com TCAR do tórax realizada em até 24 h do início dos sintomas, e com diagnóstico comprovado com base em cultura positiva de escarro ou de aspirado brônquico associada à cultura positiva de líquido pleural ou de sangue dentro de uma semana após o início dos sintomas. Foram avaliados 20 pacientes masculinos e 10 femininos, com mediana de idade de 21 anos (variação, 1-41 anos). O TMO foi realizado para o tratamento de leucemia mieloide crônica (n = 14), anemia aplástica severa (n = 6), leucemia mieloide aguda (n = 4), anemia de Fanconi (n = 3) e leucemia linfoide aguda (n = 3). Dois radiologistas analisaram os exames de TCAR, chegando a decisões finais por consenso. RESULTADOS: Os achados de TCAR mais frequentes foram consolidação do espaço aéreo (60%), pequenos nódulos centrolobulares (50%), opacidade em vidro fosco (40%), espessamento de parede brônquica (20%), nódulos grandes (20%), lesões pleurais (16,7%) e opacidades em padrão de árvore em brotamento (10%). As alterações pulmonares estavam distribuídas nas regiões centrais e periféricas dos pulmões em 15 pacientes e somente na periferia em 11 pacientes. As lesões estavam localizadas no terço inferior e no terço médio dos pulmões em 22 e 20 pacientes, respectivamente. CONCLUSÕES: Os achados de TCAR mais comuns na nossa amostra foram consolidações do espaço aéreo, pequenos nódulos centrolobulares e opacidades em vidro-fosco, distribuídos nas regiões centrais e periféricas dos terços médio e inferior dos pulmões.

OBJECTIVE: To describe HRCT findings in patients with bacterial pneumonia following bone marrow transplantation (BMT). METHODS: This was a retrospective study involving 30 patients diagnosed with bacterial pneumonia in whom HRCT of the chest was performed within 24 h after the onset of symptoms and the diagnosis was confirmed, based on a positive culture of sputum or bronchial aspirate, together with a positive pleural fluid or blood culture, within one week after symptom onset. There were 20 male patients and 10 female patients. The median age was 21 years (range, 1-41 years). The BMT had been performed for the treatment of the following: chronic myeloid leukemia, in 14 cases; severe aplastic anemia, in 6; acute myeloid leukemia, in 4; Fanconi's anemia, in 3; and acute lymphocytic leukemia, in 3. Two radiologists analyzed the HRCT scans and reached their final decisions by consensus. RESULTS: The most common HRCT findings were air-space consolidation (in 60%), small centrilobular nodules (in 50%), ground-glass opacities (in 40%), bronchial wall thickening (in 20%), large nodules (in 20%), pleural lesions (in 16.7%) and tree-in-bud opacities (in 10%). The pulmonary lesions were distributed in the central and peripheral areas in 15 patients, whereas they were exclusively peripheral in 11. Lesions were located in the lower and middle lobes of the lung in 22 and 20 patients, respectively. CONCLUSIONS: The most common HRCT findings in our patient sample were air-space consolidation, small centrilobular nodules and ground-glass opacities, most often in the central and peripheral regions of the middle and lower lung zones.

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Widening of intervertebral foramen by tortuous vertebral artery
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Ono, Sergio Eiji

; Kawasaki, Christiane Sayuri

; Coelho, Luiz Otávio de Mattos

; Lucaski, Fabiano Ferrari

; Carvalho Neto, Arnolfo de

Arquivos de Neuro-Psiquiatria

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mar 2009, Volume 67 N. 1 Pages 115 - 116

Abstract: En | Text: En | PDF: En

11806 downloads

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Aneurisma de artéria cerebral em criança com síndrome da imunodeficiência adquirida: relato de caso
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Carvalho Neto, Arnolfo de

; Bruck, Isac

; Coelho, Luiz Otávio de Mattos

; Cruz, Cristina Rodrigues da

; Liu, Cristian Bark

; Gomes, André Francisco

; Ogata, Sílvio Atsushi

; Tahan, Tony Tannous

Arquivos de Neuro-Psiquiatria

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jun 2001, Volume 59 N. 2B Pages 444 - 448

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

A dilatação aneurismática dos vasos do polígono de Willis é manifestação incomum da infecção pelo vírus da imunodeficiência adquirida (HIV), tendo sido relatados, até o momento, 15 casos na literatura. O presente estudo tem por objetivo relatar um novo caso dessa apresentação rara, além de revisar aspectos importantes relacionados à mesma. Um paciente, do sexo masculino, 6 anos de idade, com síndrome da imunodeficiência adquirida (AIDS) de transmissão perinatal e tetraparesia, desenvolveu sintomas caracterizados por episódios de crises distônicas. A tomografia computadorizada de crânio, que inicialmente era normal, mostrou dilatação aneurismática dos vasos do polígono de Willis. A revisão de literatura demonstra que os principais achados patológicos em casos similares, são, principalmente, fibrose de camada média com destruição da lâmina interna e hiperplasia da íntima. A etiologia da vasculite não é conhecida, acreditando-se que o vírus da varicela-zoster e o próprio HIV possam estar relacionados à mesma. Conclui-se que, apesar de incomum, tal complicação apresenta grande importância pelo fato dos aneurismas colocarem esses pacientes em grupo de alto risco para acidentes vasculares. A sobrevida relatada na literatura é de menos de 6 meses após o diagnóstico da arteriopatia aneurismática cerebral.

Cerebral aneurysmal arteriopathy of the circle of Willis is an uncommon manifestation of acquired human immunodeficiency virus (HIV) infection and up to now only 15 cases have been published in the literature. For this reason we add our experience of this rare case, and review the most important aspects related to this entity. The patient is a 6 year old male with perinatal transmitted AIDS, tetraparethic, developed symptoms characterized by episodes of dystonic postures. The computed tomography of the brain showed aneurismal arteriopathy of the circle of Willis. He had a previous normal examination. The review of the literature shows the pathological abnormalities of the affected vessels are mainly medial fibrosis, with destruction of the internal elastic lamina and intimal hyperplasia. The etiology for the vasculitis is unknown. Varicela zoster virus, as well as HIV by itself, can be related to the physiopathology of the vasculitis. On conclusion, it can be said that although uncommon, such complications are of great importance by the fact that the patients with vascular aneurismal arteriopathy are in high risk for vascular accidents, and once a diagnosis was made, death occurs in less than 6 months, according to the literature.

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kw	article keywords
subject	subject (title words, abstract and keywords)
ab	abstract
ta	journal short title (e.g. Cad. Saúde Pública)
journal_title	journal full title (e.g. Cadernos de Saúde Pública)
la	publication language code (e.g. pt - Portuguese, es - Spanish)
type	document type
pid	publication identifier
publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

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