Resumo O objetivo do artigo é analisar a clareza e as medidas de engajamento das publicações sobre câncer bucal nos perfis do Instagram dos órgãos oficiais de saúde no Brasil. Realizou-se um estudo infodemiológico com 81 perfis. Foram coletados dados sobre classificação do conteúdo, conta e mídia, abordagem do tema, número de postagens, curtidas, comentários, visualizações e hashtags. A clareza das publicações educativas foi avaliada pela versão brasileira do Clear Communication Index (BR-CDC-CCI). A análise dos dados envolveu a correlação de Spearman e o teste de Mann-Whitney (α = 5%). Foram encontradas 775 publicações sobre câncer bucal. O escore médio do BR-CDC-CCI foi 69,8 (DP = 15,5). A clareza das informações foi adequada em 9,5% das publicações educativas. Correlações positivas foram encontradas entre o número de curtidas e engajamento (comentários [r = 0,49], visualizações [r = 0,96]), número de hashtags (r = 0,13) e ano de publicação (r = 0,21). Publicações do Ministério da Saúde apresentaram escore do BR-CDC-CCI significativamente maior do que os demais perfis (p = 0,01). As publicações sobre câncer bucal foram correlacionadas com engajamento, ano de publicação e número de hashtags. Os órgãos públicos aumentaram as publicações para atingir a população, mas a clareza do conteúdo foi baixa.

Abstract This article aims to analyze the clarity and engagement measures of publications on oral cancer in the Instagram profiles of official health agencies in Brazil. An infodemiological study was conducted with 81 profiles. Data collected concerned content classification, account and media, manner of addressing the topic, number of posts, likes, comments, views and hashtags. The clarity of the educational publications was assessed with the Brazilian version of the Clear Communication Index (BR-CDC-CCI). Data analysis involved Spearman’s correlation and the Mann-Whitney test (α = 5%). A total of 775 publications on oral cancer were found. The average BR-CDC-CCI score was 69.8 (SD = 15.5). The clarity of the information was adequate in 9.5% of the educational publications. Positive correlations were found between the number of likes and engagement (comments [r = 0.49], views [r = 0.96]), number of hashtags (r = 0.13) and year of publication (r = 0.21). Publications from the Health Ministry had a significantly higher BR-CDC-CCI score compared to the other profiles. Publications on oral cancer were correlated with engagement, year of publication and number of hashtags. Public agencies increased publications to reach the population, but the clarity of the content was low.

Resumo O objetivo do artigo é analisar a clareza e as medidas de engajamento das publicações sobre câncer bucal nos perfis do Instagram dos órgãos oficiais de saúde no Brasil. Realizou-se um estudo infodemiológico com 81 perfis. Foram coletados dados sobre classificação do conteúdo, conta e mídia, abordagem do tema, número de postagens, curtidas, comentários, visualizações e hashtags. A clareza das publicações educativas foi avaliada pela versão brasileira do Clear Communication Index (BR-CDC-CCI). A análise dos dados envolveu a correlação de Spearman e o teste de Mann-Whitney (α = 5%). Foram encontradas 775 publicações sobre câncer bucal. O escore médio do BR-CDC-CCI foi 69,8 (DP = 15,5). A clareza das informações foi adequada em 9,5% das publicações educativas. Correlações positivas foram encontradas entre o número de curtidas e engajamento (comentários [r = 0,49], visualizações [r = 0,96]), número de hashtags (r = 0,13) e ano de publicação (r = 0,21). Publicações do Ministério da Saúde apresentaram escore do BR-CDC-CCI significativamente maior do que os demais perfis (p = 0,01). As publicações sobre câncer bucal foram correlacionadas com engajamento, ano de publicação e número de hashtags. Os órgãos públicos aumentaram as publicações para atingir a população, mas a clareza do conteúdo foi baixa. Brasil Realizouse Realizou se 8 mídia tema postagens comentários BRCDCCCI. BRCDCCCI BR CDC CCI . (BR-CDC-CCI) MannWhitney Mann Whitney α 5%. 5 5% 5%) 77 698 69 69, DP 15,5. 155 15,5 15 15,5) 95 9 9,5 r 0,49, 049 0,49 , 0 49 0,49] 0,96, 096 0,96 96 0,96]) 0,13 013 13 0,21. 021 0,21 21 0,21) p 0,01. 001 0,01 01 0,01) população baixa (BR-CDC-CCI 7 6 15, 1 9, 04 0,4 4 09 0,9 0,96] 0,1 02 0,2 2 00 0,0 0,

Abstract This article aims to analyze the clarity and engagement measures of publications on oral cancer in the Instagram profiles of official health agencies in Brazil. An infodemiological study was conducted with 81 profiles. Data collected concerned content classification, account and media, manner of addressing the topic, number of posts, likes, comments, views and hashtags. The clarity of the educational publications was assessed with the Brazilian version of the Clear Communication Index (BR-CDC-CCI). Data analysis involved Spearman’s correlation and the Mann-Whitney test (α = 5%). A total of 775 publications on oral cancer were found. The average BR-CDC-CCI score was 69.8 (SD = 15.5). The clarity of the information was adequate in 9.5% of the educational publications. Positive correlations were found between the number of likes and engagement (comments [r = 0.49], views [r = 0.96]), number of hashtags (r = 0.13) and year of publication (r = 0.21). Publications from the Health Ministry had a significantly higher BR-CDC-CCI score compared to the other profiles. Publications on oral cancer were correlated with engagement, year of publication and number of hashtags. Public agencies increased publications to reach the population, but the clarity of the content was low. Brazil 8 classification media topic posts comments BRCDCCCI. BRCDCCCI BR CDC CCI . (BR-CDC-CCI) Spearmans Spearman s MannWhitney Mann Whitney α 5%. 5 5% 5%) 77 698 69 69. SD 15.5. 155 15.5 15 15.5) 95 9 9.5 r 0.49, 049 0.49 , 0 49 0.49] 0.96, 096 0.96 96 0.96]) 0.13 013 13 0.21. 021 0.21 21 0.21) population low (BR-CDC-CCI 7 6 15. 1 9. 04 0.4 4 09 0.9 0.96] 0.1 01 02 0.2 2 0.

ABSTRACT Objective: To determine the occurrence of hyposalivation in Brazilian adults and its association with individual determinants, such as the use of medications, systemic conditions, smoking, and alcohol consumption. Material and Methods: A cross-sectional study with 402 adults was developed. Information was collected on sociodemographic and general health characteristics, and sialometry was performed with stimulated salivary flow. It indicated low salivary flow when ≤ 0.7 mL/min. Bivariate and multivariate analyses were conducted using a decision tree (p<0.05). Results: The sample was comprised predominantly of women (68.2%) aged ≤ 29 years (25.4%). Most participants did not use medication (56.7%). Among systemic diseases, the most cited was hypertension (25.1%). More than a third of the participants presented hyposalivation (40.3%), being associated with the following variables: age between 50 to 59 years (p=0.011), female sex (p<0.001), menopause (p=0.001), use of alcohol (p=0.033), systemic disease (p=0.002) and medication use (p<0.001). In multivariate analysis, in addition to sex (p<0.001) and hypertension (p=0.005), an association was also found between hyposalivation and diabetes (p=0.014). Conclusion: Factors associated with hyposalivation in adults were sex and the presence of hypertension or diabetes. Objective determinants medications conditions smoking consumption Methods crosssectional cross sectional 40 developed characteristics 07 0 7 0. mLmin mL min mL/min p<0.05. p005 p p<0.05 . 05 (p<0.05) Results 68.2% 682 68 2 (68.2% 25.4%. 254 25.4% 25 4 (25.4%) 56.7%. 567 56.7% 56 (56.7%) diseases 25.1%. 251 25.1% 1 (25.1%) 40.3%, 403 40.3% , 3 (40.3%) variables 5 p=0.011, p0011 p=0.011 011 (p=0.011) p<0.001, p0001 p<0.001 001 p=0.001, p=0.001 (p=0.001) p=0.033, p0033 p=0.033 033 (p=0.033) p=0.002 p0002 002 (p=0.002 p<0.001. analysis (p<0.001 p=0.005, p0005 p=0.005 005 (p=0.005) p=0.014. p0014 p=0.014 014 (p=0.014) Conclusion p00 p<0.0 (p<0.05 68.2 6 (68.2 25.4 (25.4% 56.7 (56.7% 25.1 (25.1% 40.3 (40.3% p001 p=0.01 01 (p=0.011 p000 p<0.00 00 p=0.00 (p=0.001 p003 p=0.03 03 (p=0.033 (p=0.00 (p<0.00 (p=0.005 (p=0.014 p0 p<0. (p<0.0 68. (68. 25. (25.4 56. (56.7 (25.1 40. (40.3 p=0.0 (p=0.01 (p=0.03 (p=0.0 p<0 (p<0. (68 (25. (56. (40. p=0. (p=0. p< (p<0 (6 (25 (56 (40 p=0 (p=0 (p< ( (2 (5 (4 p= (p= (p

Resumo Investigar determinantes individuais e contextuais associados ao bullying em escolares de 8 a 10 anos. Foi realizado estudo transversal com 739 crianças. As crianças responderam uma pergunta sobre episódios de bullying relacionado a saúde bucal, um questionário sobre ansiedade infantil e disfunção orofacial. Os responsáveis forneceram informações sobre características sociodemográficas, distúrbios do sono e alfabetismo em saúde bucal. Examinadores treinados avaliaram as crianças para diagnóstico da cárie dentária pelo International Caries Detection and Assessment System, má oclusão por meio do Dental Aesthetic Index, disfunção orofacial pelo Nordic Orofacial Test-Screening e traumatismo dentário (Critério de Andreasen) (Kappa>0,80). As variáveis contextuais foram tipo de escola e renda mensal do bairro escolar. Estatística descritiva foi utilizada para caracterização da amostra. Modelos de regressão de Poisson multinível não ajustados e ajustados (p<0,05) foram usados. A prevalência do bullying foi 13,3%. Após análise ajustada a má oclusão (RP=1.59; IC95%:1.03-2.44) e a ansiedade (RP=1.79; IC95%:1.10-2.93) permaneceram associados ao bullying. Em relação ao contexto, a menor renda mensal do bairro da escola foi associada ao bullying (RP=1.75; IC95%:1.12-2.72). Má oclusão e ansiedade influenciaram a presença do bullying. A menor renda mensal do bairro escolar foi um determinante contextual importante para o aumento da prevalência de bullying. 1 anos 73 bucal sociodemográficas System Index TestScreening Test Screening Critério Andreasen Kappa>0,80. Kappa080 Kappa Kappa>0,80 . 0 80 (Kappa>0,80) amostra p<0,05 p005 p 05 (p<0,05 usados 133 13 3 13,3% RP=1.59 RP159 RP 59 (RP=1.59 IC95%1.032.44 IC95103244 IC IC95% 1.03 2.44 IC95 03 2 44 IC95%:1.03-2.44 RP=1.79 RP179 79 (RP=1.79 IC95%1.102.93 IC95110293 1.10 2.93 93 IC95%:1.10-2.93 contexto RP=1.75 RP175 75 (RP=1.75 IC95%1.122.72. IC95112272 1.12 2.72 12 72 IC95%:1.12-2.72) 7 Kappa08 Kappa>0,8 (Kappa>0,80 p<0,0 p00 (p<0,0 13,3 RP=1.5 RP15 5 (RP=1.5 032 IC95%1.032.4 IC9510324 103 1.0 244 2.4 IC9 4 IC95%:1.03-2.4 RP=1.7 RP17 (RP=1.7 102 IC95%1.102.9 IC9511029 110 1.1 293 2.9 9 IC95%:1.10-2.9 122 IC95%1.122.72 IC9511227 112 272 2.7 IC95%:1.12-2.72 Kappa0 Kappa>0, (Kappa>0,8 p<0, p0 (p<0, 13, RP=1. RP1 (RP=1. IC95%1.032. IC951032 1. 24 2. IC95%:1.03-2. IC95%1.102. IC951102 11 29 IC95%:1.10-2. IC95%1.122.7 IC951122 27 IC95%:1.12-2.7 Kappa>0 (Kappa>0, p<0 (p<0 RP=1 (RP=1 IC95%1.032 IC95103 IC95%:1.03-2 IC95%1.102 IC95110 IC95%:1.10-2 IC95%1.122. IC95112 IC95%:1.12-2. Kappa> (Kappa>0 p< (p< RP= (RP= IC95%1.03 IC9510 IC95%:1.03- IC95%1.10 IC9511 IC95%:1.10- IC95%1.122 IC95%:1.12-2 (Kappa> (p (RP IC95%1.0 IC951 IC95%:1.03 IC95%1.1 IC95%:1.10 IC95%1.12 IC95%:1.12- (Kappa IC95%1. IC95%:1.0 IC95%:1.1 IC95%:1.12 IC95%1 IC95%:1. IC95%:1 IC95%:

Abstract Investigate individual and contextual determinants associated with bullying in schoolchildren eight to ten years of age. A cross-sectional study was conducted with 739 schoolchildren, who answered a question about episodes of bullying related to oral health and questionnaires addressing childhood anxiety and orofacial dysfunction. The guardians provided information on sociodemographic characteristics, sleep disorders, and oral health literacy. Trained examiners assessed the children for the diagnosis of dental caries using the International Caries Detection and Assessment System, malocclusion using the Dental Aesthetic Index, orofacial dysfunction using the Nordic Orofacial Test-Screening and traumatic dental injury (Andreasen criteria) (Kappa> 0.80). The contextual variables were the type of school and the monthly income of the school neighborhood. Descriptive statistics was performed to characterize the sample and unadjusted and adjusted (p <0.05) multilevel Poisson regression models were run. The prevalence of bullying was 13.3%. After the adjusted analysis, malocclusion (PR=1.59; 95%CI:1.03-2.44) and anxiety (PR=1.79; 95%CI:1.10-2.93) remained associated with bullying. In terms of context, the monthly income of the neighborhood of the school was associated with bullying (PR=1.75; 95%CI:1.12-2.72). Malocclusion and anxiety influenced the occurrence of bullying. A lower average income in the school neighborhood was an important contextual determinant for the increase in the prevalence of bullying. age crosssectional cross sectional 73 characteristics disorders literacy System Index TestScreening Test Screening Andreasen criteria Kappa> Kappa (Kappa 0.80. 080 0.80 . 0 80 0.80) p <0.05 005 05 run 133 13 3 13.3% analysis PR=1.59 PR159 PR 1 59 (PR=1.59 95%CI1.032.44 95CI103244 CI 95%CI 1.03 2.44 95 03 2 44 95%CI:1.03-2.44 PR=1.79 PR179 79 (PR=1.79 95%CI1.102.93 95CI110293 1.10 2.93 10 93 95%CI:1.10-2.93 context PR=1.75 PR175 75 (PR=1.75 95%CI1.122.72. 95CI112272 1.12 2.72 12 72 95%CI:1.12-2.72) 7 08 0.8 8 <0.0 00 13.3 PR=1.5 PR15 5 (PR=1.5 CI1 032 95%CI1.032.4 95CI10324 95CI 103 1.0 244 2.4 9 4 95%CI:1.03-2.4 PR=1.7 PR17 (PR=1.7 102 95%CI1.102.9 95CI11029 110 1.1 293 2.9 95%CI:1.10-2.9 122 95%CI1.122.72 95CI11227 112 272 2.7 95%CI:1.12-2.72 0. <0. 13. PR=1. PR1 (PR=1. 95%CI1.032. 95CI1032 1. 24 2. 95%CI:1.03-2. 95%CI1.102. 95CI1102 11 29 95%CI:1.10-2. 95%CI1.122.7 95CI1122 27 95%CI:1.12-2.7 <0 PR=1 (PR=1 95%CI1.032 95CI103 95%CI:1.03-2 95%CI1.102 95CI110 95%CI:1.10-2 95%CI1.122. 95CI112 95%CI:1.12-2. < PR= (PR= 95%CI1.03 95CI10 95%CI:1.03- 95%CI1.10 95CI11 95%CI:1.10- 95%CI1.122 95%CI:1.12-2 (PR 95%CI1.0 95CI1 95%CI:1.03 95%CI1.1 95%CI:1.10 95%CI1.12 95%CI:1.12- 95%CI1. 95%CI:1.0 95%CI:1.1 95%CI:1.12 95%CI1 95%CI:1. 95%CI:1 95%CI:

Abstract The study analyzed the clarity of publications on human papillomavirus (HPV) in the Instagram profiles of official Brazilian health agencies. An infodemiological study analyzed publications on HPV in the 81 Instagram profiles selected from the Health Ministry, States’ Health Departments, and dental councils and associations. The following data were collected: classification of content, type of profiles, type of media, how the content was addressed, number of posts, frequency, likes, comments, viewings, and hashtags, and how the HPV vaccine was addressed. The clarity of the educational publications was assessed using the Brazilian version of the Clear Communication Index (BR-CDC-CCI). Data analysis was performed with Spearman’s correlation and the Mann-Whitney test (p < 0.05). A total of 504 publications on HPV were found. The average number of likes was 528.3 (SD = 2388.2) and the average BR-CDC-CCI score was 67.1 (SD = 14.1). The quality and clarity of the information was considered adequate (BR-CDC-CCI score ≥ 90) in 6.9% of the publications. A weak positive correlation was found between the number of likes and both the BR-CDC-CCI score (r = 0.195) and number of posts (r = 0.124). Publications from the Health Ministry had a significantly higher BR-CDC-CCI score (72.9) compared to the other profiles analyzed (p = 0.01). Most publications concerned government actions, had low engagement, and written educational information was of low clarity and quality. However, the effort to reach the population was evident, with an increase in publications over the years. (HPV agencies 8 States Departments associations collected media addressed frequency comments viewings hashtags BRCDCCCI. BRCDCCCI BR CDC CCI . (BR-CDC-CCI) Spearmans Spearman s MannWhitney Mann Whitney p 0.05. 005 0.05 0 05 0.05) 50 5283 528 3 528. SD 2388.2 23882 2388 2 671 67 1 67. 14.1. 141 14.1 14 14.1) 90 69 6 9 6.9 r 0.195 0195 195 0.124. 0124 0.124 124 0.124) 72.9 729 72 (72.9 0.01. 001 0.01 01 0.01) actions engagement However evident years 00 0.0 5 52 2388. 238 14. 6. 0.19 019 19 012 0.12 12 72. 7 (72. 0. 23 0.1 (72 (7 (

Abstract Schinus terebinthifolia Raddi green fruits essential oil (EO) was evaluated regarding its phytochemical profile, antimicrobial and cytotoxic activities, and toxicity. Gas chromatography with mass spectrometry was applied to identify its constituents, thereafter the minimum inhibitory concentration, minimum bactericidal and fungicidal concentrations, and its antibiofilm activity were evaluated. The EO cytotoxicity was assessed in tumor and non-tumor human cells, and in vivo toxicity was evaluated in a Galleria mellonella model. The major constituents of S. terebinthifolia EO were alpha-phellandrene and beta-phellandrene. The EO had a weak activity against all strains of Candida albicans (MIC 1000μg/mL) and had no activity against non-albicans strains, bacteria, and C. albicans biofilm. Cytostatic activity against all tumor cell lines was shown. Additionally, cell viability remained at EO concentrations up to 62.5 μg/mL. At 16 mg/mL, 50% hemolysis was observed, and it had low toxicity in vivo. Overall, the S. terebinthifolia EO was characterized by low antimicrobial and antibiofilm activities, with no evidence of toxicity to human tumor and non-tumor cells.

Resumo O objetivo deste estudo foi avaliar o efeito de um nanocomplexo recém-desenvolvido formado entre hidroxipropil-β-ciclodextrina e 1% de tetrafluoreto de titânio (TiF4) após distintos períodos de complexação (12/72 horas) na desmineralização do esmalte bovino in vitro. Blocos de esmalte (n = 60) foram alocados para cada grupo: água Mili-Q, hidroxipropil-β-ciclodextrina, TiF4 a 1%, hidroxipropil-β-ciclodextrina + TiF4 1% após 12 horas de complexação e hidroxipropil-β-ciclodextrina + TiF4 1% após 72 horas de complexação. As amostras foram avaliadas pela microdureza superficial, microdureza transversal e micro-CT. Microscopia eletrônica de varredura / espectrometria de raios X por dispersão de energia (MEV / EDX) foram obtidas. A hidroxipropil-β-ciclodextrina + TiF4 1% após 12h de complexação resultou em um menor percentual de perda de microdureza superficial em comparação com água Mili-Q, hidroxipropil-β-ciclodextrina, TiF4 a 1% e hidroxipropil-β-ciclodextrina + TiF4 1% após 72 horas de complexação com uma ampla magnitude de efeito (de 1,307 a 2,943) e alto poder (84,9 a 99%). Todos os grupos resultaram em similar perda integrada de minerais (ΔZ) obtida por ambas as técnicas de microdureza e micro-CT. O esmalte tratado com os grupos TiF4 e TiF4 + hidroxipropil-β-ciclodextrina apresentou camada de esmalte TiO2, enquanto a avaliação de EDX identificou Ti. A solução contendo o complexo de inclusão de hidroxipropil-β-ciclodextrina + TiF4 com 12 horas de período de complexação demonstrou uma capacidade significativa para reduzir a desmineralização superficial do esmalte hígido sob um desafio cariogênico artificial.

Abstract This study aimed to evaluate the association of contextual and individual factors with Oral Health literacy (OHL) in early adolescence. This is a population-based cross-sectional study carried out with 740 12-year-old adolescents randomly selected by a two-stage probabilistic cluster sampling process from schools in Campina Grande, Brazil. The guardians provided sociodemographic information. Adolescents answered the Brazilian version of the Family Adaptability and Cohesion Scales (FACES III) to measure family functioning, and the Brazilian Rapid Estimate of Literacy in Dentistry (BREALD-30) to measure OHL. Descriptive analysis was conducted, followed by robust Poisson’s regression analysis for complex samples with a multilevel approach (p<0.05). Rate ratio (RR) and 95% confidence intervals (CI) were calculated. The two levels of the analysis were students and schools. Adolescents enrolled at schools with higher grade-retention rate had slightly worse OHL scores (RR = 0.99; 95% CI: 0.98 to 0.99). The following individual factors were associated with the level of OHL: the female sex (RR = 1.05; 95% CI: 1.01 to 1.10), mother’s schooling more than eight years (RR = 1.13; 95% CI: 1.08 to 1.19), younger guardians (RR = 0.94; 95% CI: 0.90 to 0.97) and a balanced family functioning (RR = 1.08; 95% CI: 1.01 to 1.14). Individual and contextual factors were associated with OHL in early adolescence.

Abstract Objective: To perform an in vitro analysis of antibacterial and antifungal potential of an alcoholic extract from the leaves of Guapira Graciliflora Mart. against oral microorganisms and determine its chemical composition. Material and Methods: A hydroalcoholic extract of the leaves form G. graciliflora was obtained through maceration, vacuum concentration and freeze-drying. Antibacterial and antifungal activities were evaluated against Streptococcus mutans, Streptococcus salivarius, Streptococcus oralis, Streptococcus parasanguinis, Streptococcus mitis and strains of Candida albicans using broth microdilution method. Phytochemical analysis determined the total phenolic compounds, protein concentration and total of sugars present in the extract. Results: G. Graciliflora demonstrated antifungal activity against the LM 11 and LM 410 clinical isolates of C. albicans (MIC 0.5 mg/mL and 2 mg/mL, respectively). The other microorganisms tested were resistant to the extract. The phytochemical analysis revealed 3% proteins, 13% total sugars and 17% phenolic compounds. Conclusion: G. Graciliflora has antifungal activity against clinical strains of C. albicans and exhibits proteins, sugars and phenolic compounds in its chemical composition.

RESUMO Objetivo: Relatar uma série de casos sobre o uso dos óculos audiovisuais em crianças durante o atendimento odontológico, bem como sua interferência na frequência cardíaca e percepção sobre o atendimento. Métodos: As crianças foram analisadas em três atendimentos clínicos para registro das frequências cardíacas: 1) realização da anamnese; 2) execução de um tratamento restaurador atraumático modificado (a criança usando os óculos audiovisuais) e 3) execução de um tratamento restaurador atraumático modificado sem a ferramenta de distração. O intervalo entre os atendimentos foi de até uma semana. A frequência cardíaca foi monitorada, por meio de um oxímetro de pulso e ao final da etapa dos três atendimentos, um questionário pós-tratamento foi aplicado. A amostra foi constituída por 5 crianças entre 4 e 7 anos de idade, atendidas na clínica de Odontopediatria da Universidade Estadual da Paraíba. Resultados: As frequências cardíacas individuais e as médias intermediárias do segundo atendimento, com os óculos audiovisuais, foram menores em relação ao primeiro e o terceiro; o questionário pós-tratamento revelou uma preferência no uso dos óculos audiovisuais por serem mais confortáveis, agradáveis, e por sentirem menor percepção dolorosa e ansiedade. Conclusão: A redução da frequência cardíaca com os óculos audiovisuais sugere a redução da ansiedade durante o atendimento odontológico.

ABSTRACT Objective: This study aimed to report a case series on the use of audiovisual distraction eyeglasses in children during dental care. Methods: The influence of the distraction tool on the children’s heart rate frequency and dental care experience was further investigated. The study children had their heart rate recorded during three clinical appointments and underwent the following procedures: 1) anamnesis; 2) modified atraumatic restorative treatment with the child wearing audiovisual eyeglasses; and 3) modified atraumatic restorative treatment without the use of audiovisual eyeglasses. The interval between appointments was up to one week. The heart rate was measured using a pulse oximeter, and a post-treatment questionnaire was applied after the three appointments. The sample consisted of five children aged 4 to 7 years attending the Pediatric Dental Clinics of the State University of Paraíba. Results: While wearing the audiovisual eyeglasses, the children’s individual heart rates were lower in the second dental visit as compared to the first and third ones. The post-treatment questionnaire revealed a preference for the use of audiovisual distraction eyeglasses as the children felt more comfortable, pleased, and had a reduced pain perception and anxiety. Conclusion: The heart rate decrease observed herein suggests that audiovisual eyeglasses may contribute to reducing anxiety during dental care.

Abstract: We evaluated the antifungal and antibiofilm potential of the hydroalcoholic extract of bark from Anadenanthera colubrina (vell.) Brenan, known as Angico, against Candida spp. Antifungal activity was evaluated using the microdilution technique through the Minimum Inhibitory and Fungicide Concentrations (MIC and MFC). The antibiofilm potential was tested in mature biofilms formed by Candida species and analyzed through the counting of CFU/mL and scanning electron micrograph (SEM). In vivo toxicity and therapeutic action was evaluated in the Galleria mellonella model. The treatment with the extract, in low doses, was able to reduce the growth of planktonic cells of Candida species. MIC values range between 19.5 and 39 µg/mL and MFC values range between 79 and 625 µg/mL. In addition was able to reduce the number of CFU/mL in biofilms and to cause structural alteration and cellular destruction, observed via SEM. A. colubrina showed low toxicity in the in vivo assay, having not affected the viability of the larvae at doses below 100mg/kg and high potential in the treatment of C. albicans infection. Considering its high antifungal potential, its low toxicity and potential to treatment of infections in in vivo model, A. colubrina extract is a strong candidate for development of a new agent for the treatment of oral candidiasis.

RESUMEN Objetivos Identificar el perfil de los pacientes con diagnóstico de carcinoma de células escamosas (CCE) de la boca y los factores asociados a la estadificación clínica de la enfermedad. Métodos Estudio transversal con muestra de 293 historias de pacientes portadores de CEC, atendidos en un Centro de Referencia de Oncología del municipio de Campina Grande (PB), de 2000 a 2006. Se utilizó estadística descriptiva e inferencial por medio de la Regresión Robusta de Poisson (α=5%). Resultados El sexo masculino (56,6%), los no blancos¿? (49,0%) y el grupo de más de 60 años (74,1%) fueron los más afectados por la neoplasia; la lengua (35,1%) y el paladar (21,5%) fueron los sitios más afectados; la mayoría poseía hábito de tabaquismo (37,6%) y el 60,2% presentaba etapa avanzada de la enfermedad. La estadificación clínica no se asoció al sexo, la edad, el color de la piel y a los hábitos de beber y/o fumar. Conclusiones Se observó una mayor ocurrencia de CEC en hombres, en pacientes con edad más avanzada, no blancos y que poseían hábitos de tabaquismo, pero sin asociación estadística.

ABSTRACT Objective The aim of the present study was to identify the profile of patients diagnosed with oral squamous cell carcinoma (SCC) and factors associated with the clinical stage of the disease. Materials and Method A cross-sectional study was conducted with a sample of 293 medical charts of patients with SCC treated at an oncology reference center in the city of Campina Grande (Brazil) between 2000 and 2006. Descriptive and inferential statistics were performed with robust Poisson regression (α=5%). Results Males (56.6%), non-white individuals (49.0%) and individuals over than 60 years of age (74.1%) were the most affected by SCC. The tongue (35.1%) and palate (21.5%) were the most common sites. A large portion of the patients were smokers (37.6%) and 60.2% were in an advanced stage of the disease. Clinical staging was not associated with sex, age, skin color or drinking and/or smoking habits. Conclusion There was a higher incidence of SCC in men, older patients, non-white individuals and smokers. Clinical staging was not associated with the variables analyzed.

ABSTRACT Objective The aim of the present study was to identify the profile of patients diagnosed with oral squamous cell carcinoma (SCC) and factors associated with the clinical stage of the disease. Materials and Method A cross-sectional study was conducted with a sample of 293 medical charts of patients with SCC treated at an oncology reference center in the city of Campina Grande (Brazil) between 2000 and 2006. Descriptive and inferential statistics were performed with robust Poisson regression (α=5%). Results Males (56.6%), non-white individuals (49.0%) and individuals over than 60 years of age (74.1%) were the most affected by SCC. The tongue (35.1%) and palate (21.5%) were the most common sites. A large portion of the patients were smokers (37.6%) and 60.2% were in an advanced stage of the disease. Clinical staging was not associated with sex, age, skin color or drinking and/or smoking habits. Conclusion There was a higher incidence of SCC in men, older patients, non-white individuals and smokers. Clinical staging was not associated with the variables analyzed.

RESUMEN Objetivos Identificar el perfil de los pacientes con diagnóstico de carcinoma de células escamosas (CCE) de la boca y los factores asociados a la estadificación clínica de la enfermedad. Métodos Estudio transversal con muestra de 293 historias de pacientes portadores de CEC, atendidos en un Centro de Referencia de Oncología del municipio de Campina Grande (PB), de 2000 a 2006. Se utilizó estadística descriptiva e inferencial por medio de la Regresión Robusta de Poisson (α=5%). Resultados El sexo masculino (56,6%), los no blancos¿? (49,0%) y el grupo de más de 60 años (74,1%) fueron los más afectados por la neoplasia; la lengua (35,1%) y el paladar (21,5%) fueron los sitios más afectados; la mayoría poseía hábito de tabaquismo (37,6%) y el 60,2% presentaba etapa avanzada de la enfermedad. La estadificación clínica no se asoció al sexo, la edad, el color de la piel y a los hábitos de beber y/o fumar. Conclusiones Se observó una mayor ocurrencia de CEC en hombres, en pacientes con edad más avanzada, no blancos y que poseían hábitos de tabaquismo, pero sin asociación estadística.

Abstract: The aim of this study was to evaluate in vitro the antifungal, antibiofilm and antiproliferative activities of the extract from the leaves of Guapira graciliflora Mart. The phytochemical characterization of the extract was performed using electrospray ionization mass spectrometry (ESI-MS). The antimicrobial activity of the extract and its fractions was evaluated using the broth microdilution method against species of Candida. The inhibition of C. albicans biofilm was evaluated based on the number of colony-forming units (CFU) and metabolic activity (MTT). The antiproliferative activity of the extract and its fraction was evaluated in the presence of human tumor and non-tumor cells, and the cytotoxicity of the extract was determined on the RAW 264.7 macrophage line – both using the sulforhodamine B method. The phytochemical characterization indicated the presence of the flavonoids rutin and kaempferol. The extract and the methanol fraction exhibited moderate antifungal activity against C. albicans, C. krusei, and C. glabrata, and strong activity against C. dubliniensis. In the biofilms at 24 and 48 hours, the concentration of 12500 µg/mL of the extract was the most effective at reducing the number of CFU s/mL (44.4% and 42.9%, respectively) and the metabolic activity of C. albicans cells (34.6% and 52%, respectively). The extract and its fractions had no antiproliferative effect on the tumor lines tested, with mean activity (log GI50) equal to or greater than 1.71 µg/mL. Macrophage cell viability remained higher than 80% for concentrations of the extract of up to 62.5 µg/mL. G. graciliflora has flavonoids in its chemical composition and demonstrates potential antifungal and antibiofilm activity, with no evidence of a significant change in the viability of human tumor and non-tumor cell lines.

RESUMO Os odontomas são considerados os tipos mais comuns de tumores odontogênicos e frequentemente diagnosticados na segunda década de vida. Possuem crescimento lento, comportamento benigno e assintomático, favorecendo sua permanência intraóssea por muito tempo até demonstrarem algum sinal clínico ou serem detectados em radiografias de rotina. O objetivo deste relato foi apresentar um caso clínico de um paciente de 13 anos de idade, sexo masculino, que apresentou atraso na esfoliação do canino decíduo inferior direito. No exame radiográfico, verificou-se uma imagem radiopaca na região anterior da mandíbula, produzida por estruturas que lembravam a formação de dentes, circundada por uma área radiolúcida. Adjacente à lesão, na parte basal, identificou-se a presença do canino permanente inferior direito incluso, apresentando desvio do seu eixo de erupção. O diagnóstico clínico foi definido como odontoma composto. O tratamento consistiu na remoção da lesão e erupção do dente incluso associado, por meio de intervenções cirúrgicas, sem tração ortodôntica, com três anos de acompanhamento e resultados positivos. Existe a possibilidade de erupção cirurgicamente guiada de dente retido, com desvio do seu eixo de erupção e associado à odontoma, através da remoção da lesão e da barreira física (ostectomia) sem tração ortodôntica.

ABSTRACT Odontoma is the most common type of odontogenic tumor and is most often diagnosed in the second decade of life. This benign tumor has a slow growth and is asymptomatic, which favors its persistence in the bone until some clinical sign emerges or the tumor or be detected in a routine radiograph. The aim of this case report was to present a clinic case of a 13-year-old male, who presented delayed exfoliation of the mandibular right primary canine. The radiographic exam revealed a radiopaque image in the anterior region of the mandible produced by structures that resembled the formation of teeth surrounded by a radiolucent area. Adjacent to the tumor, the impacted mandibular right canine was identified with deviation of its eruption axis. The clinical diagnosis was compound odontoma. Treatment consisted of the removal of the tumor and the surgically-assisted eruption of the tooth without orthodontic traction. After three years of follow up, the patient has exhibited positive results. It is possible to surgically assist the eruption of an impacted tooth, with a deviated axis, associated with an odontoma through the removal of the tumor and of the physical barrier (ostectomy) without orthodontic traction.

<p>O objetivo do presente estudo foi avaliar a percepção dos pais sobre saúde bucal de pré-escolares. Um estudo transversal foi realizado com 843 crianças brasileiras entre três e cinco anos de idade. Os pais/responsáveis responderam a um questionário autoaplicável sobre a saúde de seus filhos e dados sociodemográficos. Percepções dos pais sobre a saúde bucal de seus filhos foram determinados pela resposta à seguinte pergunta: "Como você descreveria a saúde bucal do seu filho?" A versão brasileira da Early Childhood Oral Health Impact Scale (B-ECOHIS) foi respondido por pais/responsáveis e usada para medir o impacto da qualidade de vida relacionada à saúde bucal (OHRQoL) em crianças pré-escolares e suas famílias. Três examinadores realizaram exames bucais nas crianças (K=0,85-0,90). Análise descritiva foi realizada, seguida de uma análise de regressão logística para amostras complexas (α=5%). As seguintes variáveis foram significativamente associados com a percepção dos pais sobre saúde bucal dos filhos: percepção ruim dos pais sobre a saúde geral (OR=18,25; IC 95%: 3,36-98,96), impacto negativo sobre OHRQoL da família (OR=13,82; IC 95%: 4,27-44,72), crianças com idade de cinco anos (OR=7,40; IC 95%: 1,49-36,63) e a interação entre o histórico da dor de dente e cárie dentária (OR=10,02; IC 95%: 1,17-85,61). Percepções parentais de saúde bucal são influenciados pelo impacto sobre OHRQoL da família, a percepção ruim dos pais sobre a saúde geral do seu filho, e as condições clínicas com sintomas, tais como cárie dentária com dor de dente. Outros problemas bucais, tais como má oclusão ou traumatismo dentário, não foram associados com a percepção dos pais sobre saúde bucal de seus filhos.</p>

<p>The aim of the present study was to evaluate parental perceptions of oral health status in preschool children. A cross-sectional study was carried with 843 Brazilian children between 3 and 5 years of age. Parents/guardians answered a self-administered questionnaire on the health of their children and sociodemographic data. Parental perceptions of their child's oral health were determined by the responses to the following question: "How would you describe your child's oral health?" The Brazilian version of the Early Childhood Oral Health Impact Scale (B-ECOHIS) was answered by parents/guardians and used to measure the impact of oral health-related quality of life (OHRQoL) on preschool children and their families. Three examiners performed oral exams on the children (K= 0.85-0.90). Descriptive analytical statistics were carried out, followed by logistic regression for complex samples (α=5%). The following variables were significantly associated with parental perceptions of children's oral health: parental perception of general health as poor (OR=18.25; 95% CI: 3.36-98.96), negative impact on family's OHRQoL (OR=13.82; 95% CI: 4.27-44.72), child aged five years (OR=7.40; 95% CI: 1.49-36.63) and the interaction between history of toothache and dental caries (OR=10.02; 95% CI: 1.17-85.61). Thus, parental perceptions of oral health are influenced only by clinical conditions with symptoms, such as dental caries with toothache. Other oral conditions, such as malocclusion or traumatic dental injury, were not associated with parental perceptions of their child's oral health.</p>