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Impacto del uso de diversos marcos de seguridad en las auditorías informáticas dentro de las organizaciones: Revisión sistemática
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Burgos-Rojas, Marco Antonio

; Haro-Polo, Carlos Isaac

; Santos, Alberto Carlos Mendoza-de los

Revista Científica de la UCSA

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aug 2024, Volume 11 N. 2 Pages 103 - 115

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT In a world where attacks on the information security of organizations have increased, computer auditing emerges as a solution to prevent these unwanted incidents. However, to ensure the effectiveness of these audits, the use of an appropriate security framework is essential. This review article offers a comprehensive analysis of how different security frameworks can influence the effectiveness of computer audits in organizations. A systematic review has been conducted, which includes original articles published in English and Spanish between 2018 and 2023, and available in recognized databases such as Sciencedirect, Springerlink, JSTOR, Dialnet, Scielo, Scopus, and Latinindex.The main purpose of the study is to understand how the implementation of a specific security framework, such as COBIT, LCCI, NIST, CSF, ISG, D4I, and ISO/IEC 27001, can affect computer audits and their corresponding impact on organizations. In addition, it has been discovered that the choice of the security framework can have a significant repercussion on an organization's ability to identify and mitigate security risks, as well as to maintain regulatory compliance and ensure the integrity and confidentiality of data.

RESUMEN En un mundo donde los ataques a la seguridad de la información en las organizaciones se han incrementado, surge la auditoría informática como una solución para prevenir estos sucesos no deseados. No obstante, para asegurar la efectividad de estas auditorías, es imprescindible el uso de un marco de seguridad adecuado. Este artículo de revisión proporciona un estudio completo sobre cómo distintos marcos de seguridad pueden impactar en la efectividad de las auditorías de sistemas en las organizaciones. Se llevó a cabo una revisión sistemática que comprende artículos originales, publicados en inglés y español desde 2018 hasta 2023, y accesibles en bases de datos reconocidas como Sciencedirect, Springerlink, JSTOR, Dialnet, Scielo, Scopus y Latinindex. El propósito principal del estudio es comprender cómo la implementación de un marco de seguridad específico, como COBIT, LCCI, NIST, CSF, ISG, D4I y ISO/IEC 27001, puede afectar las auditorías informáticas y su correspondiente impacto en las organizaciones. Adicionalmente, se ha encontrado que la selección del marco de seguridad puede impactar de manera importante en la habilidad de una organización para detectar y minimizar los riesgos de seguridad, mantener la conformidad con las regulaciones y asegurar la integridad y confidencialidad de los datos.

https://doi.org/10.18004/ucsa/2409-8752/2024.011.02.0103

APLICACIÓN DE BASE CEREAL LOCAL (ZEA MAYS L. Y ORYZA SATIVA) EN PRODUCCIÓN DE CERVEZA ARTESANAL
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García Paz, Gema María

; Lucas Rojas, Cristhyan Antonio

; Alcívar Cedeño, Ulbio Eduardo

; Cedeño Palacios, Carlos Alfredo

; Burgos Briones, Gabriel Alfonso

; Munizaga Párraga, Diego Roberto

Centro Azúcar

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mar 2024, Volume 51 N. 1 elocation e1050

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: Beer is the most popular alcoholic beverage in the world and the use of additives during its production can improve its physicochemical and organoleptic properties. Objective: To evaluate the physicochemical and sensory characteristics of craft beer by applying a corn and rice cereal base for malt substitution. Materials and Methods: The cereal base (corn and rice) was purchased in the local market of the Portoviejo canton, province of Manabí and two samples, T1 and T2, were made compared with a control sample in which the physicochemical parameters such as density, pH and alcohol content were determined and the sensory determination of the samples was carried out by 27 untrained panelists. Results and Discussion: Significant differences were found in density and alcoholic content, with sample T2 being the one that obtained the best results in the sensory aspect, being the one preferred by the panelists surveyed. Conclusions: The overall assessment of sample B indicates that it was considered to be of higher quality and preference compared to sample A. These results highlight the importance of innovation in the beer industry, since the inclusion of local ingredients can not only improve the flavor profile of beer, but also contribute to the promotion of local and sustainable products.

RESUMEN Introducción: La cerveza es la bebida alcohólica más popular del mundo y el empleo de aditivos durante su elaboración pueden mejorar las propiedades fisicoquímicas y organolépticas de la misma. Objetivo: Evaluar las características fisicoquímicas y sensoriales de la cerveza artesanal mediante la aplicación de una base cereal de maíz y arroz para la sustitución de la malta. Materiales y Métodos: La base cereal (maíz y arroz) se adquirió en el mercado local del cantón Portoviejo, provincia de Manabí y se realizaron dos muestras T1 y T2 comparadas con una muestra control en la cual, se determinaron los parámetros fisicoquímicos como densidad, pH y contenido alcohólico y la determinación sensorial de las muestras se realizó mediante 27 panelistas no entrenados. Resultados y Discusión: Se encontraron diferencias significativas en la densidad y en el contenido alcohólico siendo la muestra T2 la que obtuvo mejores resultados en el aspecto sensorial siendo la preferida por los panelistas encuestados. Conclusiones: La valoración global de la muestra B, indica que fue considerada de mayor calidad y preferencia en comparación con la muestra A. Estos resultados resaltan la importancia de la innovación en la industria cervecera, ya que la inclusión de ingredientes locales puede no solo mejorar el perfil de sabor de la cerveza, sino también contribuir a la promoción de productos locales y sostenibles.

Redução da germinação de feijão-preto (Phaseolus vulgaris L.) sob armazenamento em frio e ambiente
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Calderón, Agatha Teresa Rosado

; León, Manuel Jesús Zavala

; Díaz, Johnny Abraham Burgos

; Haas, Jorge Ismael Tucuch

; Mendoza, Marco Antonio Torres

; Fajardo, María Alma Rangel

Revista de Ciências Agrárias

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dec 2023, Volume 46 N. 4 Pages 31 - 40

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO As características de armazenamento das sementes contribuem para manter o diminuir a qualidade das mesmas. Neste pressuposto, o objetivo do estudo consistiu em analisar o efeito do frio durante vários períodos de tempo em 12 cultivares de feijão-preto. Para cada cultivar determinou-se o peso de 100 sementes armazenadas tanto em condição ambiental (27,22 °C e 62 % HR) quanto em frío (4,1°C e 13 % HR) durante 18 meses, nos quais se tomaram amostras ao início, 3, 6, 9, 12 e 18 meses para avaliar a porcentagem de germinação e plântulas anormais. Durante o armazenamento diminuiu a germinação e aumentaram as plântulas anormais. Identificaram-se diferenças entre as cultivares, das quais ‘Comapa’ tolera o armazenamento sob condições do trópico com somente 16,5 pontos porcentuais de redução, enquanto as cultivares ‘Veracruz’ e ‘Exp. 2’ registraram reduções de 50,5 e 40 pontos porcentuais, respectivamente.

Abstract The seed storage characteristics will contribute to maintaining or decreasing the quality of the seeds themselves. In this assumption, the objective of the study was to analyze the effect of cold during several periods of time in 12 black bean cultivars. The twelve black bean varieties were conditioned, the weight of 100 seeds was determined and they were stored under two conditions (27,22 ° C and 62 % HR) and refrigerated (4,1°C and 13 % HR) for 18 months, in which samples were taken at the beginning, 3, 6, 9, 12 and 18 months to evaluate the percentage of germination and abnormal seedlings. During storage, germination decreased and abnormal seedlings increased. Differences were identified among the varieties of which ‘Comapa’ tolerated storage under tropical conditions with only 16,5 percentage points of reduction while the ‘Veracruz’ and ‘Exp. 2’ varieties recorded reductions of 50,5 and 40 percentage points, respectively.

https://doi.org/10.19084/rca.31413

Clinical Text Mining in Spanish Enhanced by NegationDetection and Named Entity Recognition
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Tamayo Herrera, Antonio Jesús

; Burgos, Diego A.

; Gelbukh, Alexander

Computación y Sistemas

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dec 2023, Volume 27 N. 4 Pages 1169 - 1181

Abstract: En | Text: En | PDF: En

Abstract: Automatic identification of negation, uncertainty, and named entities are tasks of vital importance for clinical text mining. While several works have been published in English, only in recent years Spanish cases have been considered. In this work, we present a transfer learning framework based on a RoBERTa model pre-trained with biomedical documents and on multilingual BERT to identify diseases and organisms mentions as well as negations and uncertainty cues and scopes as a sequence labeling problem, utilizing the fact clinical datasets in Spanish for these four tasks. Our approach achieves results comparable to the state-of-the-art organism mentions identification and negation identification, competitive results in identifying diseases, and establishing state-of-the-art for uncertainty identification. Additionally, to remedy the lack of a unified dataset for the four tasks addressed, models to tackle them have been integrated into a web application that we built to allow effective clinical text mining in Spanish. The source code of this work is publicly available as well as the web application.

https://doi.org/10.13053/cys-27-4-4783

Helmintofauna gastrointestinal de peces dulceacuícolas comerciales proveniente de dos provincias de la costa ecuatoriana: patrones ecológicos y potencial zoonótico
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Santos-Pinargote, Jaime

; Loor-Velez, Yelsin

; Torres-Noboa, Antonio

; Burgos-Teran, Milena

; Cuadrado-Saldarriaga, Stefania

; Paladines-Jaramillo, Madeleine

; Cárdenas-Callirgos, Jorge Manuel

Revista de Investigaciones Veterinarias del Perú

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dec 2023, Volume 34 N. 6 elocation e24746

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT The aim of this work was to evaluate the helminth fauna present in continental commercial fish from the provinces of Guayas (Daule and Salitre) and Los Ríos (Vinces and Babahoyo). In total, 2317 individuals from 11 fish species were analysed. Fifteen species of parasitic helminths were identified, these being the digenean trematodes: Clinostomum complanatum, Clinostomum sp1, Clinostomum sp2, Clinostomum sp3, Cladorchiidae sp1, Cladorchiidae sp2, Cladorchiidae sp3, the cestodes: Nominoscolex sp y Proteocephalus sp, the nematodes: Contracaecum sp, Cucullanus sp, Procamallanus sp1, Procamallanus sp2, y Rhabdochona sp and acanthocephalan Acanthocephalus sp. The locality and the fish with the highest balance in terms of parasitic abundance was Vinces and Andinoacara rivulatus, respectively. The anisakid parasite Contracaecum sp presented the highest values of prevalence, mean abundance and mean intensity in the four locations and in all the fish except for A. rivulatus, which registered Clinostomun sp1 as the helminth with the highest prevalence among the parasites reported for this fish.

RESUMEN El objetivo de este trabajo fue evaluar la helmintofauna presente en peces comerciales continentales de las provincias del Guayas (Daule y Salitre) y Los Ríos (Vinces y Babahoyo). Se analizaron 2317 individuos a partir de 11 especies de peces. Se identificaron 15 especies de helmintos parásitos siendo estas los trematodos digeneos: Clinostomum complanatum, Clinostomum sp1, Clinostomum sp2, Clinostomum sp3, Cladorchiidae sp1, Cladorchiidae sp2, Cladorchiidae sp3, los cestodos: Nominoscolex sp y Proteocephalus sp, los nematodos: Contracaecum sp Cucullanus sp Procamallanus sp1, Procamallanus sp2, y Rhabdochona sp y el acantocéfalo Acanthocephalus sp. Se determinó que la localidad y el pez con mayor equilibrio en cuanto abundancia parasitaria fue en Vinces y Andinoacara rivulatus, respectivamente. El parasito anisákido Contracaecum sp presentó los valores más altos de prevalencia, abundancia media, e intensidad media en las cuatro localidades y en todos los peces a excepción de A. rivulatus que registró a Clinostomun sp1 como el helminto con mayor prevalencia entre los parásitos reportados para este pez.

https://doi.org/10.15381/rivep.v34i6.24746

Hacia los nuevos escenarios en la Educación. 2° Congreso internacional de la innovación y la tecnología en Educación
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Herrera-Pavo, Miguel Ángel

; Orellana-Navarrete, Verónica

; Jaramillo Baquerizo, Christian Paúl

; Balladares Burgos, Jorge Antonio

Revista Andina de Educación

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oct 2023, Volume 6 N. 2 elocation e100

Abstract: Es | Text: Es | PDF: Es

https://doi.org/10.32719/26312816.2022.6.2.0

Costo del tamizaje y tratamiento oportuno versus el manejo integral de la discapacidad visual severa por retinopatía del prematuro
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del Busto Wilhelm, Evelyn

; Zimmermann Paiz, Martin Arturo

; Ordóñez Rivas, Ana Marissa

; Quezada del Cid, Nancy Carolina

; Burgos Elías, Verónica Yaneth

; Rousselin Monterroso, Allan Antonio

Andes pediatrica

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jun 2023, Volume 94 N. 3 Pages 333 - 338

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen: La retinopatía del prematuro (ROP) es una de las principales causas de ceguera prevenible a nivel mundial. En Guatemala un gran número de prematuros nacen en hospitales fuera de la ciudad capital y se presentan a una evaluación con estadios avanzados de la enfermedad. Objetivo: Comparar el costo del tamizaje y tratamiento oportuno versus el costo total del manejo integral de pacientes en condición de discapacidad visual secundaria a ROP. Pacientes y Método: Se calculó el costo de la enfermedad en pacientes que consultaron con baja visión o ceguera secundario a ROP. Los costos directos fueron calculados en base a aquellos en relación directa con el manejo de la enfermedad: atención médica, rehabilitación, educación, soporte técnico, transporte, asistencia personal, adaptaciones y equipamiento del hogar, comparandolos con los costos del tamizaje y tratamiento oportuno. Resultados: El costo total de manejar a un niño en condición de discapacidad visual severa por ROP es de USD 214.666,37 y el de tamizaje y tratamiento oportuno de USD 1.223,12. Esto representa un costo adicional de USD 213.443,24 en los pacientes que no fueron tamizados y tratados a tiempo. Conclusión: El costo del tamizaje y tratamiento oportuno significa sólo el 0,57% del costo total que implica el manejo durante la esperanza de vida de un niño en condición de discapacidad visual severa.

Abstract: Retinopathy of prematurity (ROP) is one of the leading causes of preventable blindness worldwide. In Guatemala, a large number of premature infants are born in hospitals outside the capital city and present for evaluation at advanced stages of the disease. Objective: To compare the cost of screening and timely treatment versus the total cost of comprehensive management of patients with visual impairment secondary to ROP. Patients and Method: The cost of the disease was calculated in patients who consulted due to low vision or blindness secondary to ROP. Direct costs were calculated based on those directly related to the management of the disease: medical care, rehabilitation, education, technical support, transportation, personal assistance, adaptations, and home equipment, compared with the costs of screening and timely treatment. Results: The total cost of managing a child with severe visual impairment due to ROP is USD 214,666.37 and the cost of screening and timely treatment is USD 1,223.12, meaning an additional cost of USD 213,443.24 in patients who were not screened and treated on time. Conclusion: The cost of screening and timely treatment represents only 0.57% of the total cost of lifelong management of a child with severe visual impairment.

https://doi.org/10.32641/andespediatr.v94i3.4530

Costo del tamizaje y tratamiento oportuno versus el manejo integral de la discapacidad visual severa por retinopatía del prematuro
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del Busto Wilhelm, Evelyn

; Zimmermann Paiz, Martin Arturo

; Ordóñez Rivas, Ana Marissa

; Quezada del Cid, Nancy Carolina

; Burgos Elías, Verónica Yaneth

; Rousselin Monterroso, Allan Antonio

Andes pediatrica

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2023, N. ahead

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

https://doi.org/10.32641/andespediatr.v94i3.4530

Cross-cultural invariance of the Spanish version of the COVID-19 Assessment Scorecard to measure the perception of government actions against COVID-19 in Latin America Crosscultural Cross cultural COVID19 COVID 19 COVID-1 COVID1 1 COVID-
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Caycho-Rodríguez, Tomás

; Valencia, Pablo D.

; Ventura-León, José

; Carbajal-León, Carlos

; Vilca, Lindsey W.

; Reyes-Bossio, Mario

; Delgado-Campusano, Mariel

; Yupanqui-Lorenzo, Daniel E.

; Paredes-Angeles, Rubí

; Rojas-Jara, Claudio

; Gallegos, Miguel

; Cervigni, Mauricio

; Martino, Pablo

; Polanco-Carrasco, Roberto

; Palacios, Diego Alejandro

; Moreta-Herrera, Rodrigo

; Samaniego-Pinho, Antonio

; Rivera, Marlon Elías Lobos

; Figares, Andrés Buschiazzo

; Puerta-Cortés, Diana Ximena

; Corrales-Reyes, Ibraín Enrique

; Calderón, Raymundo

; Gallegos, Walter L. Arias

; Petzold, Olimpia

; Camargo, Andrés

; Torales, Julio

; Blanco, J. Arkangel Monge

; González, Pedronel

; Smith-Castro, Vanessa

; Rivera, Wendy Yamilet Matute

; Ferrufino-Borja, Daniela

; Ceballos-Vásquez, Paula

; Muñoz-del-Carpio-Toia, Agueda

; Palacios, Jorge

; Burgos-Videla, Carmen

; León, Ana María Eduviges Florez

; Vergara, Ibeth

; Vega, Diego

; Barria-Asenjo, Nicol A.

; Schulmeyer, Marion K.

; Rios, Hassell Tatiana Urrutia

; Lira, Arelly Esther Lira

Psicologia: Reflexão e Crítica

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2023, Volume 36 elocation 34

Abstract: En | Text: En | PDF: En

Abstract Objectives The present study aimed to evaluate the measurement invariance of a general measure of the perception of governmental responses to COVID-|19 (COVID-SCORE-10) in the general population of 13 Latin American countries. Methods A total of 5780 individuals from 13 Latin American and Caribbean countries selected by non-probabilistic snowball sampling participated. A confirmatory factor analysis was performed and the alignment method was used to evaluate invariance. Additionally, a graded response model was used for the assessment of item characteristics. Results The results indicate that there is approximate measurement invariance of the COVID-SCORE-10 among the participating countries. Furthermore, IRT results suggest that the COVID-SCORE-10 measures with good psychometric ability a broad spectrum of the construct assessed, especially around average levels. Comparison of COVID-SCORE-10 scores indicated that participants from Cuba, Uruguay and El Salvador had the most positive perceptions of government actions to address the pandemic. Thus, the underlying construct of perception of government actions was equivalent in all countries. Conclusion The results show the importance of initially establishing the fundamental measurement properties and MI before inferring the cross-cultural universality of the construct to be measured. COVID|19 COVID19 COVID |19 19 COVID-|1 COVIDSCORE10 COVIDSCORE SCORE 10 (COVID-SCORE-10 1 578 nonprobabilistic non probabilistic participated Additionally characteristics COVID-SCORE-1 Furthermore assessed levels Cuba pandemic Thus crosscultural cross cultural measured COVID|1 COVID1 |1 COVID-| COVIDSCORE1 (COVID-SCORE-1 57 COVID-SCORE- COVID| | COVID- (COVID-SCORE- 5 COVID-SCORE (COVID-SCORE

https://doi.org/10.1186/s41155-023-00277-9

10.

Environmental conditions affect herbicide selectivity on paddy rice in Southern Brazil
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Martini, Luiz Fernando Dias

; Fipke, Marcus Vinícius

; Noldin, José Alberto

; Roma-Burgos, Nilda

; Piveta, Leonard Bonilha

; Moura, Diogo Silva

; Benedetti, Lariza

; Schreiber, Fabio

; Scherner, Ananda

; Avila, Luis Antonio de

Ciência Rural

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2023, Volume 53 N. 4 elocation e20210671

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: A produtividade do arroz no Sul do Brasil aumentou linearmente ao longo dos anos. A semeadura no início da janela é o principal contribuinte para o aumento da produtividade do arroz no sul do Brasil. No entanto, essa prática pode expor as plântulas de arroz ao estresse por baixa temperatura, aumentando os danos do herbicida e reduzindo a produtividade do arroz. Este trabalho teve como objetivo avaliar o efeito de épocas de semeadura na seletividade de herbicidas em caracteres agronômicos do arroz. Conduzimos experimentos de campo durante as safras 2010/11 e 2011/12 em Capão do Leão, RS, Brasil. O delineamento experimental foi em blocos casualizados completos com arranjo fatorial. O fator A foram a semeadura-precoce (em setembro) e a semeadura-tardia (em novembro); o fator B foram os tratamentos com herbicidas (bispyribac-sodium, cyhalofop-butyl, penoxsulam, metsulfuron-methyl e controle - sem herbicida). A resposta do arroz aos tratamentos com herbicidas diferiu entre os anos. Em 2010/11, o bispyribac-sodium, o penoxsulam e o metsulfuron-methyl prejudicaram o arroz apenas na semeadura-precoce. Em ambos os anos, a semeadura precoce do arroz promoveu maior potencial de rendimento, apesar dos danos dos herbicidas. As injúrias causadas pelos herbicidas bispyribac-sodium, penoxsulam e metsulfuron-methyl foram transitórias, não acarretando em perdas de produtividade. A temperatura fria próxima a aplicação aumenta a injúria dos herbicidas ALS.

ABSTRACT: Rice yield in Southern Brazil has increased linearly over the years. Early season sowing is the primary contributor to rice yield increase in Southern Brazil. However, that practice might expose rice seedlings to the risk of low-temperature stress, which can enhance herbicide injury and reduce rice yield. This research evaluated the effect of sowing dates on herbicide selectivity and agronomical rice traits. We conducted field experiments during the 2010/11 and 2011/12 growing seasons in Capão do Leão, RS, Brazil. The experimental design was a complete randomized block with a factorial arrangement. Factor A was early-sowed (in September) and late-sowed (in November); factor B was herbicide treatment (bispyribac-sodium, cyhalofop-butyl penoxsulam, metsulfuron-methyl, and nontreated check). Rice response to herbicide treatments differed between years. In 2010/11, bispyribac-sodium, penoxsulam, and metsulfuron-methyl injured rice only on early-sowed. In both years, early sowing rice promoted higher yield potential despite herbicide injury. The injury caused by the herbicides bispyribac-sodium, penoxsulam and metsulfurom-methyl was transient did not lead to yield losses. Cold temperature close the application increases the injury of ALS herbicides.

https://doi.org/10.1590/0103-8478cr20210671

11.

Importancia pronóstica de las mutaciones del gen promotor de la transcriptasa inversa de la telomerasa en los meningiomas de alto grado
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Cañas, Alejandro

; Jiménez, Enrique

; Hakim, Fernando

; Mejía, Juan Armando

; Ramón, Juan Fernando

; Gómez, Diego

; Jaramillo-Velásquez, Daniel

; Bermúdez, Sonia

; Useche, Nicolás

; Pineda, Diego

; Cifuentes, Hernando

; Becerra, Antonio

; Muñoz, Álvaro

; Santoyo, Nicolás

; Ruiz-Patiño, Alejandro

; Sotelo, Carolina

; Archila, Pilar

; Rodríguez, July

; Ávila, Jenny

; Ordóñez-Reyes, Camila

; García-Robledo, Juan Esteban

; Ricaurte, Luisa

; Rojas, Leonardo

; Feo, Óscar

; Burgos, Remberto

; Ramírez, Carlos

; Arrieta, Óscar

; Zataraín-Barrón, Lucía

; Vargas, Carlos

; Carranza, Hernán

; Otero, Jorge

; Cardona, Andrés F.

Biomédica

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dec 2022, Volume 42 N. 4 Pages 574 - 590

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Introducción. En los meningiomas, ocurren con frecuencia mutaciones en la región promotora de la transcriptasa inversa de la telomerasa. Objetivo. Estimar la importancia pronóstica de las mutaciones de la transcriptasa inversa de la telomerasa en pacientes colombianos con meningiomas de grados II y III. Materiales y métodos. Es un estudio de cohorte, retrospectivo y multicéntrico, que incluyó pacientes con diagnóstico de meningioma persistente o recidivante, de grados II y III, según la clasificación de la OMS, reclutados entre el 2011 y el 2018, con tratamiento sistémico (sunitinib, everolimus con octreótido o sin él, y bevacizumab). El estado de la mutación del promotor de la transcriptasa inversa de la telomerasa se determinó por medio de la PCR. Resultados. Se incluyeron 40 pacientes, en 21 (52,5 %) de los cuales se encontraron mutaciones en la transcriptasa inversa de la telomerasa, siendo las variantes más frecuentes la C228T (87,5 %) y la C250T (14,3 %). Estas fueron más frecuentes entre los pacientes con meningiomas anaplásicos (p=0,18), en aquellos con más de dos recurrencias (p=0,04), y en los que presentaron lesiones en la región parasagital y la fosa anterior (p=0,05). Los sujetos caracterizados por tener alteraciones puntuales fueron tratados con mayor frecuencia con la serie de medicamentos everolimus, sunitinib y bevacizumab (p=0,06). Tras el inicio del tratamiento médico, la supervivencia global fue de 23,7 meses (IC95% 13,1-34,2) en los pacientes con mutaciones y, de 43,4 meses (IC95% 37,5-49,3), entre aquellos sin mutaciones (p=0,0001). Los resultados del análisis multivariado demostraron que, únicamente, el número de recurrencias y la presencia de mutaciones en el gen de la transcriptasa inversa de la telomerasa, fueron factores que afectaron negativamente la supervivencia global. Conclusiones. Las mutaciones en el gen promotor de la transcriptasa inversa de la telomerasa permiten identificar los pacientes con alto riesgo, cuya detección podría ser de utilidad para seleccionar el mejor esquema terapéutico.

Abstract Introduction: Mutations in the promoter region of telomerase reverse transcriptase occur frequently in meningiomas. Objective: To estimate the prognostic importance of telomerase reverse transcriptase mutations in Colombian patients with grades II and III meningioma. Materials and methods: This was a multicenter retrospective cohort study of patients diagnosed with refractory or recurrent WHO grades II and III meningiomas, recruited between 2011 and 2018, and treated with systemic therapy (sunitinib, everolimus ± octreotide, and bevacizumab). Mutation status of the telomerase reverse transcriptase promoter was established by PCR. Results: Forty patients were included, of which telomerase reverse transcriptase mutations were found in 21 (52.5%), being C228T and C250T the most frequent variants with 87.5 % and 14.3 %, respectively. These were more frequent among patients with anaplastic meningiomas (p=0.18), with more than 2 recurrences (p=0.04); and in patients with parasagittal region and anterior fossa lesions (p=0.05). Subjects characterized as having punctual mutations were more frequently administered with everolimus, sunitinib and bevacizumab drug series (p=0.06). Overall survival was 23.7 months (CI95% 13.1-34.2) and 43.4 months (CI95% 37.5-49.3; p=0.0001) between subjects with and without mutations, respectively. Multivariate analysis showed that the number of recurrences and the presence of telomerase reverse transcriptase mutations were the only variables that negatively affected overall survival. Conclusions: Mutations in telomerase reverse transcriptase allows the identification of high-risk patients and could be useful in the selection of the best medical treatment.

https://doi.org/10.7705/biomedica.6100

12.

Automatic determination of the Atterberg limits with machine learning
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Rosas, David Antonio

; Burgos, Daniel

; Branch, John Willian

; Corbi, Alberto

DYNA

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dec 2022, Volume 89 N. 224 Pages 34 - 42

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen En este estudio, determinamos el límite líquido (W1), el índice de plasticidad (PI) y el límite plástico (Wp) de suelos naturales finos con ayuda de machine-learning y métodos estadísticos. Ello permite localizarlos en la Carta de Plasticidad de Casagrande con una sola medida en extractores de presión-membrana. Los modelos de machine-learning mostraron ajustes en la determinación de W l apropiados para propósitos de diseño, comparados con métodos estandarizados. Ajustes similares se alcanzaron en la determinación de PI, mientras que las determinaciones de W p permiten ajustes apropiados para trabajos de control. Debido a que las técnicas más apropiadas se basaron en Regresión Lineal Múltiple y Máquinas de Soporte de Vectores, aportaron modelos de plasticidad explicables. En este sentido, Wl = (9.94 ± 4.2) + (2.25 ± 0.3) ∙pF4.2, PI = (-20.47 ± 5.6) + (1.48 ± 0.3) ∙pF4.2 + (0.21 ± 0.1) ∙F, y Wp = (23.32 ± 3.5) + (0.60 ± 0.2) ∙pF4.2 - (0.13 ± 0.04) ∙F. Por consiguiente, proponemos un método alternativo, automático, estático y multimuestra para enfrentar problemas frecuentes en la determinación de los Límites de Atterberg con ensayos normalizados.

Abstract In this study, we determine the liquid limit (W1), plasticity index (PI), and plastic limit (Wp) of several natural fine-grained soil samples with the help of machine-learning and statistical methods. This enables us to locate each soil type analysed in the Casagrande plasticity chart with a single measure in pressure-membrane extractors. These machine-learning models showed adjustments in the determination of the liquid limit for design purposes when compared with standardised methods. Similar adjustments were achieved in the determination of the plasticity index, whereas the plastic limit determinations were applicable for control works. Because the best techniques were based in Multiple Linear Regression and Support Vector Machines Regression, they provide explainable plasticity models. In this sense, Wl = (9.94 ± 4.2) + (2.25 ± 0.3) ∙pF4.2, PI = (-20.47 ± 5.6) + (1.48 ± 0.3) ∙pF4.2 + (0.21 ± 0.1) ∙F, and Wp = (23.32 ± 3.5) + (0.60 ± 0.2) ∙pF4.2 - (0.13 ± 0.04) ∙F. So that, we propose an alternative, automatic, multi-sample, and static method to address current issues on Atterberg limits determination with standardised tests.

https://doi.org/10.15446/dyna.v89n224.102619

13.

Impacto de las tecnologías de la educación en los procesos educativos
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Checa Cabrera, Marco Antonio

; León Burgos, Gabriela Paulina

; Molina Mora, José Fabian

Conrado

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dec 2022, Volume 18 N. 89 Pages 340 - 350

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Given the widespread use of technologies in social and daily life, educational institutions have assimilated them as part of their reality. Multiple studies have been aimed at knowing the role of these in the educational environment and its effects. The objective of the research is to analyze the impact of educational technologies in educational processes. To accomplish this, theoretical and empirical methods were used, such as the DEMATEL method. The Science Direct and Google Scholar databases were searched. Scientific production is extensive, reaching 2,394 publications since 1999. Depending on the type of article, there is a predominance of research articles, followed by book chapters. The most treated areas of knowledge are the social sciences, followed by medicine and dentistry. There is a lack in relation to studies on the effectiveness of these tools in the teaching process. Once the implications related to the use of information technologies and the application of the Dematel method have been identified, it can be seen that in relation to the degree of importance, relevance of the teacher's role in the technological environment ranks first.

RESUMEN Ante el uso generalizado de las tecnologías en la vida social y cotidiana, las instituciones educativas las han asimilado como parte de su realidad. Múltiples estudios se han encaminado a conocer el papel de estas en el entorno educativo y sus efectos. Por lo antes expuesto se define como objetivo de la investigación: analizar el impacto de las tecnologías de la educación en los procesos educativos. Para cumplirlo, se emplearon métodos teóricos y empíricos. Se realizaron búsquedas en las bases de datos Science Direct y Google Scholar. Como resultado se obtuvo que la producción científica es amplia, alcanzando 2394 publicaciones desde 1999, según el tipo de artículo existe un predominio de los artículos de investigación, seguidos por los capítulos de libros. Las áreas del conocimiento más tratadas son las ciencias sociales, seguido de la medicina y estomatología. Se aprecia una carencia en relación con los estudios sobre la efectividad de estas herramientas en el proceso docente. Una vez identificadas las implicaciones relacionadas con el empleo de las tecnologías de la información y la aplicación del método Dematel, se observa que, en relación con el grado de importancia, relevancia del papel del profesor en el entorno tecnológico ocupa el primer lugar.

14.

Lo político para una nueva cultura política poscovid-19: reflexiones desde la democracia y la participación ciudadana
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Balladares Burgos, Jorge Antonio

Estado & comunes, revista de políticas y problemas públicos

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dec 2022, Volume 2 N. 15 Pages 101 - 113

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen El propósito de este artículo es esbozar los componentes de una cultura política poscovid, que permitiría a las personas ciudadanas disponer de herramientas para nueva praxis política. Categorías como democracia y participación ciudadana, en tanto elementos constitutivos del diálogo y la interacción con el Estado en un contexto de crisis, pueden ser insumos para entender el nuevo ámbito y dinámicas de lo político. El estudio presenta una revisión de fuentes bibliográficas para definir y analizar los principales elementos que conforman esta nueva cultura. Entre los hallazgos están las formas cotidianas de la organización, la voluntad y conciencia de la ciudadanía como potenciales bases de una nueva cultura política. Este modus vivendi permitiría una participación ciudadana solidaria, activa y responsable que promueva respuestas y soluciones con miras a fortalecer la democracia en contextos de post pandemia.

Abstract This article outlines the components of a post-covid political culture. Categories such as democracy and citizen participation, as constitutive elements of dialogue and interaction with the State in a context of crisis, can be inputs to understand the new sphere and dynamics of politics. This study presents a literature review to gather and analyse the main elements that make up this new culture. Among the findings, this paper pictures human relations, daily forms of organization and the will and conscience of the citizenry are arguably the basis for a new political culture. This modus vivendi would give way to solidarity, active, and responsible citizen participation to promote responses and solutions towards strengthening post-pandemic democracy.

https://doi.org/10.37228/estado_comunes.v2.n15.2022.271 75 downloads

15.

La responsabilidad social desde el aprendizaje-servicio en la formación del docente
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Martínez-Valdivia, Estefanía

; Burgos-García, Antonio

; Pegalajar-Palomino, Ma Carmen

Perfiles educativos

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sep 2022, Volume 44 N. 177 Pages 58 - 77

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Las directrices propuestas por la Agenda 2030 han planteado, en la educación superior, el desarrollo de competencias para la sostenibilidad en la formación inicial del docente. La finalidad de este estudio es analizar la producción científica sobre competencias y formación del futuro docente en relación con el aprendizaje-servicio (ApS) y sus implicaciones para la responsabilidad social (RS). Se realizó una revisión sistemática en las bases de datos científicas más importantes (WoS, ProQuest, Google Académico y Scopus). Los resultados muestran que el ApS es una metodología didáctica eficaz para la formación inicial del docente en relación con el desarrollo de su formación integral y de la competencia cívica y ciudadana. Además, promueve la construcción de la identidad profesional basada en el desarrollo sostenible. Las conclusiones destacan que el ApS incide en la formación en responsabilidad social del futuro docente, en tanto que promueve una concienciación ante los colectivos sociales más vulnerables.

Abstract The guidelines proposed by the 2030 Agenda have raised the need for the development of sustainability skills in higher education teachers’ training since the very beginning. The main purpose of this study is to analyze the scientific production on skills and on the training of future teachers in relation to service-learning (SL) and its implications for social responsibility (SR). In order to do this, we carried out a systematic review of the most important scientific databases (WoS, ProQuest, Google Scholar and Scopus). The results show that Learning plus service is an effective didactic methodology for the initial training of teachers regarding the development of their comprehensive training as well as their civic and citizen competence. In addition, it promotes the construction of a professional identity based on sustainable development. The conclusions highlight that the Learning plus service approach impacts a teacher’s training in social responsibility, insofar as it promotes awareness before the most vulnerable social groups.

https://doi.org/10.22201/iisue.24486167e.2022.177.60653

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