The antifouling booster biocides are frequently studied for toxic effects on the aquatic ecosystems. The present investigation proposes passive silicone rubber samplers as a collection method for biocides, once these methods can concentrate substances in aqueous matrices at very low levels. Through the passive sampler-water partition coefficient (Ksw) and the analyte chemical nature, we can optimize their extraction from the membrane to apply in the sample medium. We used the co-solvent method to determine the Ksw of three third-generation antifouling biocides, chlorothalonil, dichlofluanid, and dichlorooctylisothiazolinone (DCOIT), with log Ksw = 2.24, 4.01, and 2.38, respectively. Improving extraction also led to a recovery range higher than 70%, determinations were carried out by gas chromatography with an electron capture detector. Biocides concentration in seawater samples from Itaqui port (São Marcos Bay, northern Brazil) ranged from 0.058 to 0.72 µg L-1 for chlorothalonil, 0.001 to 0.008 µg L-1 for dichlofluanid, and 0.018 to 0.64 µg L-1 for DCOIT. ecosystems levels samplerwater sampler water (Ksw nature medium cosolvent co solvent thirdgeneration third generation chlorothalonil dichlofluanid DCOIT, DCOIT , (DCOIT) 224 2 24 2.24 401 4 01 4.01 238 38 2.38 respectively 70 70% detector São Bay Brazil 0058 0 058 0.05 072 72 0.7 L1 L 1 L- 0001 001 0.00 0008 008 0018 018 0.01 064 64 0.6 (DCOIT 22 2.2 40 4.0 23 3 2.3 7 005 05 0.0 07 0. 000 00 06 6 2. 4.

ABSTRACT Given the large differences in the results of inoculation and co-inoculation in the bean crop, an experiment in cultivating winter beans was carried out in 2019 under greenhouse conditions with the aim of evaluating the performance of the beans and a possible increase in plant growth and grain production, using seeds inoculated or co-inoculated with Rhizobium tropici and Azospirillum brasilense, with and without fungicide and/or insecticide, in sandy and clayey soils. A total of 112 pots were used, and 14 treatments were applied in a completely randomised experimental design, with four replications. The Scott-Knott test was used to analyse the results, and showed that whether using untreated seeds or carrying out complete chemical treatment with fungicide and insecticide plus co-inoculation with R. tropici and A. brasilense, winter bean production was reduced in clayey soil, while the joint use of fungicide and insecticide, fungicide and R. tropici, or fungicide, insecticide and R. tropici, favoured shoot development. Inoculating with A. brasilense, without R. tropici and with insecticide, or insecticide and fungicide, favoured greater root growth in clayey soil. In sandy soil, grain production was higher using seeds treated solely with insecticide, solely with R. tropici, or with a combination of both. Production was lower in the joint treatment with fungicide, insecticide and the co-inoculation of bacteria, or when using insecticide together with A. brasilense. coinoculation co crop 201 coinoculated brasilense andor soils 11 1 design replications ScottKnott Scott Knott R soil development both bacteria 20 2

Resumo Objetivou-se identificar características indicadoras de precocidade sexual de fácil mensuração e que podem ser registradas em menor idade (idade à primeira concepção - IPC), além de estimar as correlações genéticas dessa característica com aquelas de crescimento e carcaça em bovinos Nelore. A IPC foi considerada a idade em que a fêmea apresentou o primeiro diagnóstico positivo de prenhez. A estimativa dos componentes de (co)variância e dos parâmetros genéticos foi realizada usando modelo animal linear em análises bicaracterísticas. As estimativas de herdabilidade foram moderadas, indicando viabilidade de seleção genética para características de crescimento, carcaça e precocidade sexual. As correlações genéticas obtidas entre o IPC e a idade ao primeiro parto (IPP) foram altas (0,88), indicando a viabilidade do uso de IPC como critério de seleção para parto em idade precoce de novilhas. As estimativas de correlações genéticas entre IPC e IPP com peso aos 120, 210, 365 e 450 dias de idade e características de carcaça foram moderadas e negativas (-0,33 a -0,62). Assim, a seleção genética para animais com IPC e IPP precoces aumentaria o rendimento de carcaça, a deposição de gordura e o peso corporal, embora não afete o peso ao nascer e o ganho de peso diário. Os resultados deste estudo encorajam o uso de IPC em bovinos Nelore, uma vez que esta característica apresentou variabilidade genética em bovinos Nelore, podendo ser utilizada como critério de seleção para melhorar a precocidade sexual. Quando o objetivo de seleção genética é aumentar a precocidade sexual das novilhas, indica-se o uso de IPC como critério, pois a mensuração desta característica ocorre em idade menor IPP. Objetivouse Objetivou se IPC, , IPC) Nelore prenhez covariância co variância bicaracterísticas (IPP 0,88, 088 0,88 0 88 (0,88) novilhas 120 210 36 45 0,33 033 33 (-0,3 0,62. 062 0,62 . 62 -0,62) Assim corporal diário indicase indica 08 0,8 8 (0,88 12 21 3 4 0,3 03 (-0, 06 0,6 6 -0,62 0, (0,8 1 2 (-0 -0,6 (0, (- -0, (0 ( -0

Abstract The aim was to identify predictive traits of relatively easy measurement and which can be recorded early in life (age at first conception - AFCo), besides estimating its genetic correlations with growth and carcass traits in Nellore cattle. Age at first conception was considered the age at which the female had the first positive diagnosis for pregnancy. The estimation of (co)variance components and genetic parameters was performed using a linear animal model in two-trait analysis. The estimates of heritability were moderate, enabling genetic selection for growth-, carcass-, and sexual precocityrelated traits. The genetic correlation obtained between AFCo and age at first calving (AFCa) was high (0.88), indicating the feasibility of using AFCo as a selection criterion for early calving heifers. Genetic correlation estimates between AFCo and AFCa with weight at 120, 210, 365, and 450 days of age and carcass traits were moderate and negative (-0.33 to -0.62). Thus, genetic selection for animals with early AFCo and AFCa would enhance carcass yield, fat deposition, and growth performance, despite not affecting birth weight or daily weight gain. The results of this study encourage the use of AFCo in Nellore cattle since this trait displayed enough genetic variability in Nellore cattle, and can be used as selection criteria to improve sexual precocity. When the objective of genetic selection is to increase heifer sexual precocity, we could use the first trait as a criterion, as the measurement of this trait occurs at a lower AFCa. AFCo, , AFCo) pregnancy covariance co variance twotrait two analysis growth, growth- carcass, carcass- (AFCa 0.88, 088 0.88 0 88 (0.88) heifers 120 210 365 45 0.33 033 33 (-0.3 0.62. 062 0.62 . 62 -0.62) Thus yield deposition performance gain precocity 08 0.8 8 (0.88 12 21 36 4 0.3 03 3 (-0. 06 0.6 6 -0.62 0. (0.8 1 2 (-0 -0.6 (0. (- -0. (0 ( -0

Abstract Objective Autism spectrum disorder (ASD) is characterized by persistent deficits in social communication and social interaction and by restricted and repetitive patterns of behavior. Some studies have shown that substances derived from Cannabis sativa improve the quality of life of children with ASD without causing serious adverse effects, thus providing an alternative therapeutic option. The objective of this study was to evaluate the efficacy and safety of a cannabis extract rich in cannabidiol (CBD) in children with ASD. Methods In this randomized, double-blind, placebo-controlled clinical trial, 60 children, aged from 5 to 11 years, were selected and divided into two groups: the treatment group, which received the CBD-rich cannabis extract, and the control group, which received the placebo. They both used their respective products for a period of 12 weeks. Statistical analysis was done by two-factor mixed analysis of variance (two-way ANOVA). Results Significant results were found for social interaction (F1,116 = 14.13, p = 0.0002), anxiety (F1,116 = 5.99, p = 0.016), psychomotor agitation (F1,116 = 9.22, p = 0.003), number of meals a day (F1,116 = 4.11, p = 0.04), and concentration (F1,48 = 6.75, p = 0.01), the last of which was only significant in mild ASD cases. Regarding safety, it was found that only three children in the treatment group (9.7%) had adverse effects, namely dizziness, insomnia, colic, and weight gain. Conclusion CBD-rich cannabis extract was found to improve one of the diagnostic criteria for ASD (social interaction), as well as features that often co-exist with ASD, and to have few serious adverse effects. (ASD behavior effects option CBD (CBD randomized doubleblind, doubleblind double blind, blind double-blind placebocontrolled placebo controlled trial 6 1 years groups CBDrich weeks twofactor factor twoway way ANOVA. ANOVA . ANOVA) F1,116 F1116 F F1 116 (F1,11 1413 14 13 14.13 0.0002, 00002 0.0002 , 0 0002 0.0002) 599 99 5.99 0.016, 0016 0.016 016 0.016) 922 9 22 9.22 0.003, 0003 0.003 003 0.003) 411 4 4.11 0.04, 004 0.04 04 0.04) F1,48 F148 48 (F1,4 675 75 6.75 0.01, 001 0.01 01 0.01) cases 9.7% 97 7 (9.7% dizziness insomnia colic gain interaction, interaction) coexist co exist F1,11 F111 (F1,1 141 14.1 0000 0.000 000 59 5.9 92 2 9.2 0.00 00 41 4.1 0.0 F1,4 F14 (F1, 67 6.7 9.7 (9.7 F1,1 F11 14. 5. 9. 4. 0. F1, (F1 6. (9. (F (9 (

This work investigated the post-modification of commercial poly(methyl mechacrylate-co-acrylic acid) using the versatile multicomponent Ugi reaction. This reaction introduces diverse functionalities to tailor the polymer properties effectively. The commercial copolymer which is known for biocompatibility and drug delivery application was subjected to the Ugi reaction, altering its chemical structure. The structure of the modified polymer was checked by Fourier transform infrared spectroscopic and nuclear magnetic resonance and thermal characterizations, confirming successful Ugi component integration. Additionally, gel permeation chromatography assessed molecular weight changes. Results revealed enhanced thermal stability of the modified polymers compared to unmodified polymer, potentially advantageous in high-temperature applications. In summary, the study demonstrates efficient poly(methyl mechacrylate-co-acrylic acid) post modification through a multicomponent Ugi reaction, yielding tailored polymers. Comprehensive spectroscopic, thermal, and gel permeation analyses shed light on structural changes and improved stability, pivotal for innovative applications like drug delivery. postmodification polymethyl poly methyl mechacrylatecoacrylic mechacrylate co acrylic acid effectively characterizations integration Additionally hightemperature high temperature summary

RESUMO Objetivo: identificar as condições de letramento em saúde e sua associação com o perfil sociodemográfico e clínico da população atendida na atenção primária à saúde. Método: estudo transversal realizado com 386 pacientes atendidos em uma Unidade Básica de Saúde no Distrito Federal, Brasil. Foi realizada entrevista individual, utilizando questionário para coleta de dados sociodemográfico e de saúde dos pacientes, além da versão brasileira do Health Literacy Questionnaire. A coleta de dados ocorreu entre maio e agosto de 2022 e os dados foram analisados por meio de estatística descritiva e inferencial. Resultados: a maioria dos participantes do estudo era composta por mulheres (76,1%), na faixa etária de 18 a 40 anos (76,1%), com autopercepção de saúde classificada como boa (38%). Os escores médios do Health Literacy Questionnaire variaram entre 2,36 e 3,73, indicando limitações no letramento em saúde, especialmente nas escalas de ‘Compreensão e apoio dos profissionais de saúde’ (2,36), ‘Informações suficientes para cuidar da saúde’ (2,52), ‘Cuidado ativo’ (2,67) e ‘Navegar no sistema de saúde’ (2,98). Conclusão: os dados encontrados indicam fatores que podem ser trabalhados na população estudada para ampliar o nível de letramento em saúde, com o objetivo de aumentar a autonomia do paciente e sua corresponsabilização para um cuidado primário contínuo, resolutivo e seguro. Objetivo Método 38 Federal Brasil individual 202 inferencial Resultados 76,1%, 761 76,1% , 76 1 (76,1%) 4 38%. 38% . (38%) 236 2 36 2,3 373 3 73 3,73 Compreensão 2,36, (2,36) Informações 2,52, 252 2,52 52 (2,52) Cuidado ativo 2,67 267 67 (2,67 Navegar 2,98. 298 2,98 98 (2,98) Conclusão contínuo seguro 20 76,1 7 (76,1% (38% 23 2, 37 3,7 (2,36 25 2,5 5 (2,52 2,6 26 6 (2,6 29 2,9 9 (2,98 76, (76,1 (38 3, (2,3 (2,5 (2, (2,9 (76, (3 (2 (76 ( (7

ABSTRACT Objective: to identify the conditions of health literacy and their association with the sociodemographic and clinical profile of the population treated in primary healthcare. Method: a cross-sectional study was conducted with 386 patients treated at a Basic Health Unit in the Federal District, Brazil. Individual interviews were conducted using a questionnaire to collect sociodemographic and health data from patients, in addition to the Brazilian version of the Health Literacy Questionnaire. Data collection took place between May and August 2022, and the data were analyzed using descriptive and inferential statistics. Results: the majority of study participants were women (76.1%), aged 18 to 40 years (76.1%), with self-perceived health classified as good (38%). The average scores on the Health Literacy Questionnaire ranged from 2.36 to 3.73, indicating limitations in health literacy, especially on the scales of ‘Understanding and support from health professionals’ (2.36), ‘Sufficient information to take care of health’ (2.52), ‘Active care’ (2.67) and ‘Navigating the health system’ (2.98). Conclusion: the data found indicate factors that can be worked on in the studied population to increase the level of health literacy, with the aim of increasing patient autonomy and their co-responsibility for continuous, effective and safe primary care. Objective healthcare Method crosssectional cross sectional 38 District Brazil 2022 statistics Results 76.1%, 761 76.1% , 76 1 (76.1%) 4 selfperceived self perceived 38%. 38% . (38%) 236 2 36 2.3 373 3 73 3.73 Understanding professionals 2.36, (2.36) Sufficient 2.52, 252 2.52 52 (2.52) Active 2.67 267 67 (2.67 Navigating system 2.98. 298 2.98 98 (2.98) Conclusion coresponsibility co responsibility continuous 202 76.1 7 (76.1% (38% 23 2. 37 3.7 (2.36 25 2.5 5 (2.52 2.6 26 6 (2.6 29 2.9 9 (2.98 20 76. (76.1 (38 3. (2.3 (2.5 (2. (2.9 (76. (3 (2 (76 ( (7

RESUMEN Objetivo: identificar las condiciones de alfabetización en salud y su asociación con el perfil sociodemográfico y clínico de la población atendida en la atención primaria de salud. Método: Estudio transversal realizado con 386 pacientes atendidos en una Unidad Básica de Salud del Distrito Federal, Brasil. Se realizó una entrevista individual, utilizando un cuestionario para recolectar datos sociodemográficos y de salud de los pacientes, además de la versión brasileña del Health Literacy Questionnaire. La recolección de datos se realizó entre mayo y agosto de 2022 y los datos se analizaron mediante estadística descriptiva e inferencial. Resultados: la mayoría de los participantes del estudio fueron mujeres (76,1%), con edades entre 18 y 40 años (76,1%), con autopercepción de salud clasificada como buena (38%). Las puntuaciones medias del Cuestionario de Alfabetización en Salud oscilaron entre 2,36 y 3,73, lo que indica limitaciones en la alfabetización en salud, especialmente en las escalas de ‘Comprensión y apoyo de los profesionales de la salud’ (2,36), ‘Información suficiente para cuidar la salud’ (2,52), ‘Atención activa’ (2,67) y ‘Navegación por el sistema sanitario’ (2,98). Conclusión: los datos encontrados indican factores que pueden ser trabajados en la población estudiada para incrementar el nivel de alfabetización en salud, con el objetivo de incrementar la autonomía y corresponsabilidad del paciente para una atención primaria continua, resolutiva y segura. Objetivo Método 38 Federal Brasil individual Questionnaire 202 inferencial Resultados 76,1%, 761 76,1% , 76 1 (76,1%) 4 38%. 38% . (38%) 236 2 36 2,3 373 3 73 3,73 Comprensión 2,36, (2,36) Información 2,52, 252 2,52 52 (2,52) Atención activa 2,67 267 67 (2,67 Navegación sanitario 2,98. 298 2,98 98 (2,98) Conclusión continua segura 20 76,1 7 (76,1% (38% 23 2, 37 3,7 (2,36 25 2,5 5 (2,52 2,6 26 6 (2,6 29 2,9 9 (2,98 76, (76,1 (38 3, (2,3 (2,5 (2, (2,9 (76, (3 (2 (76 ( (7

Abstract Isopods of the suborder Cymothoida include ectoparasite species that cause physical damage and affect the development of the host by feeding on blood and tissues. On fishes, these parasites attach themselves to the skin, fins, gills, and oral cavity using claws on articulated legs. The ability to remain hidden in cavities even after the fish is caught enables isopods to be transported to new areas along with the host, making these parasites potential co-invaders. Understanding the role and environmental impact of parasites is essential, although research on parasitism in the context of biological invasions lags in comparison to general research on such invasions. Previous records indicate only two species of parasitic isopods in the São Francisco River basin. However, the present study reports the first record of two other species (Braga patagonica and Braga nasuta) on Pygocentrus piraya and in the basin itself. This demonstrates a lack of knowledge regarding fish parasites in the region, despite the presence of other parasites. Collaborations with research groups conducting fish sampling in the basin can contribute to expanding knowledge on these parasites and the training of human resources in fish parasitology. The present study provides important information on the presence of unidentified parasitic isopods on fishes in the São Francisco River basin, underscoring the need for further studies and expanding the geographic distribution of these parasites, as well as the host list for these isopods. tissues skin fins gills legs coinvaders. coinvaders co invaders. invaders co-invaders essential However nasuta itself region parasitology

Resumo: Este artigo analisou o processo de construção e execução de uma pesquisa acerca da gravidez na adolescência com jovens do ensino médio no cotidiano de uma escola pública estadual de Fortaleza-CE, a partir de um estudo qualitativo com base na pesquisa-intervenção. Por meio de um curso de extensão para estudantes secundaristas, desenvolveu-se uma pesquisa na escola em que as próprias jovens da escola pública foram copesquisadoras do tema gravidez na adolescência no cotidiano escolar. Utilizou-se as ferramentas metodológicas de diários de campo, questionário on-line e restituição. Os resultados mostraram que há diferenças nos papéis de mãe e pai na adolescência, dificuldades para a conclusão da vida escolar e prejuízos na inserção no mercado de trabalho, principalmente para as meninas. Portanto, a pesquisa possibilitou problematizar o lugar de representatividade das pautas de maternidade e paternidade fomentando espaços de escuta e dialogicidade na promoção da equidade com estudantes que experienciam a maternidade e paternidade. Resumo FortalezaCE, FortalezaCE Fortaleza CE, CE Fortaleza-CE pesquisaintervenção. pesquisaintervenção intervenção. intervenção pesquisa-intervenção secundaristas desenvolveuse desenvolveu se Utilizouse Utilizou campo online on line restituição trabalho meninas Portanto

Résumé : Cet article a analysé la construction et réalisation d’une recherche avec de lycéens sur la grossesse adolescente dans la vie quotidienne d’une école publique de Fortaleza-CE, dès une étude qualitative de recherche-intervention. Avec un cours d’extension pour des élèves du secondaire, une recherche a été menée où les élèves de l’école publique étaient co-chercheurs sur la grossesse adolescente dans l’école. Des journaux de terrain, des questionnaires en ligne et des restitutions ont été utilisés. Les résultats ont montré des différences dans les rôles de mère et de père pendant l’adolescence, des difficultés à mener à terme leur scolarité et des préjudices dans leur insertion sur le marché du travail, surtout pour les filles. Donc, la recherche a permis de questionner la représentativité des enjeux de maternité et de paternité, en favorisant des espaces d’écoute et de dialogue pour promouvoir l’équité avec les étudiants qui vivent la maternité et la paternité. dune d FortalezaCE, FortalezaCE Fortaleza CE, CE Fortaleza-CE rechercheintervention. rechercheintervention intervention. intervention recherche-intervention dextension extension secondaire lécole l cochercheurs co chercheurs lécole. école. terrain utilisés ladolescence, ladolescence adolescence, adolescence l’adolescence travail filles Donc paternité découte écoute léquité équité

Abstract: This article aimed to analyze the process of constructing and conducting research on teenage pregnancy with high school students in the daily life of a public school in Fortaleza, Ceará, based on a qualitative study using the Intervention Research approach. By an extension course for high school students, a research project was developed in the school in which the public school students themselves were co-researchers on the topic of teenage pregnancy in the school environment. The methodological tools used were field journals, online questionnaires, and restitution. Results showed differences in the roles of the mother and father during adolescence, difficulties in completing education, and obstacles in entering the job market, especially for girls. Therefore, this research could question the representation of maternity and paternity issues, promoting spaces for listening and dialogue in the promotion of equity with students who experience parenthood. Abstract Fortaleza Ceará approach coresearchers co researchers environment journals questionnaires restitution adolescence education market girls Therefore issues parenthood

Resumen: Este artículo tuvo como objetivo analizar el proceso de construcción e implementación de una investigación con estudiantes de secundaria sobre el tema del embarazo adolescente en la vida cotidiana de una escuela pública de Fortaleza, Ceará (Brasil), basada en un estudio cualitativo de investigación-intervención. A partir de un curso de extensión, se desarrolló una investigación en la escuela donde las propias estudiantes de secundaria fueron coinvestigadoras sobre el tema del embarazo adolescente. Se utilizaron como herramientas metodológicas un cuestionario en línea, diario de campo y restitución. Los resultados mostraron diferencias en el papel de la madre y el padre durante la adolescencia, dificultades para completar la vida escolar y dificultades para entrar en el mercado laboral, especialmente para las chicas. Por lo tanto, esta investigación permitió problematizar el papel representacional de la maternidad y la paternidad, propiciando espacios de escucha y de diálogo para promover la equidad con los estudiantes que experimentan estos roles. Resumen Fortaleza Brasil, Brasil , (Brasil) investigaciónintervención. investigaciónintervención intervención. intervención investigación-intervención extensión línea restitución adolescencia laboral chicas tanto paternidad roles (Brasil

ABSTRACT Methionine (Met) and cysteine (Cys) are nutrients in broiler diets, responsible for strengthening protein synthesis, immunity, and metabolic regulation. To estimate the ideal digestible Met + Cys:digestible Lysine (Lys) ratio for broilers under a lipopolysaccharide (LPS) inflammatory challenge, 384 male broilers were distributed in a completely randomized 4×2 factorial design, with four ratios of dig. Met + Cys:dig. Lys (0.69, 0.73, 0.77, and 0.81) and two conditions (with or without challenge). Each treatment had eight replicates, with six birds per experimental unit (EU). The evaluated parameters included broilers’ weight gain (WG), feed intake (FI), and feed conversion ratio (FCR); jejunum mRNA transcript levels of nuclear factor kappa-B (NF-Κb), glutathione peroxidase (GPX), superoxide dismutase (SOD), glutathione synthetase (GSS), and methionine adenosyltransferase 2 (MAT2); relative weights of liver and spleen, and fat mass (%) and lean mass (%). A linear regression model would estimate the ideal ratio if an effect had occurred. No interaction (p>0.05) was observed between the factors for all the data, nor did the different ratios had any effect (p>0.05) either. LPS-administered exhibited reduced performance, heavier liver and spleen, and lower GSS expression. Hence, the lowest dig Met + Cys:dig Lys ratio (0.69) was sufficient to maintain the performance parameters, the relative weight of lymphoid organs, fat and lean mass, and NF-Kb, GPX, SOD, GSS, MAT2, and CBS mRNA transcript levels in the jejunum. (Met Cys (Cys diets synthesis immunity regulation Cysdigestible (Lys LPS (LPS challenge 38 42 4 4× design Cysdig. Cysdig 0.69, 069 0 69 (0.69 073 73 0.73 077 77 0.77 0.81 081 81 challenge. . challenge) replicates EU. EU (EU) WG, WG , (WG) FI, FI (FI) FCR (FCR) kappaB kappa B NFΚb, NFΚb NF Κb (NF-Κb) GPX (GPX) SOD (SOD) (GSS) MAT2 MAT (MAT2) spleen % (% %. occurred p>0.05 p005 p 05 (p>0.05 data either LPSadministered administered expression Hence 0.69 organs NFKb, NFKb Kb, Kb NF-Kb 3 06 6 (0.6 07 7 0.7 0.8 08 8 (EU (WG (FI (FCR (NF-Κb (GPX (SOD (GSS (MAT2 ( p>0.0 p00 (p>0.0 0.6 (0. 0. (MAT p>0. p0 (p>0. (0 p>0 (p>0 p> (p> (p

ABSTRACT Currently, COVID-19 and tuberculosis (TB) are the deadliest infectious diseases worldwide. Their synergy, form of presentation, morbidity, and mortality are data that have been scarcely explored. Thus, this study aimed to characterize the clinical, epidemiological, and laboratory factors of this co-infection and to analyze the factors associated with the active TB among COVID-19 cases. A case-control study was conducted with a retrospective survey of 21 laboratory-confirmed COVID-19/TB co-infected patients (case group) and 21 COVID-19 patients (control group). The study included participants from eight hospitals in Campo Grande city, capital of Mato Grosso do Sul State, Brazil, from March 2020 to March 2022. Association analysis and binomial logistic regression were employed with statistical significance set at p≤0.05. From the 21 identified cases of COVID-19/TB co-infection, we found a more frequent association with HIV infection than the control-group, without worsening the outcome. COVID-19/TB patients had less dyspnea and less need for mechanical ventilation compared to the cases with COVID-19 only. On the other hand, COVID-19/TB patients had higher levels of C-reactive protein and lower hemoglobin levels, the latter variable was independently associated with COVID-19/TB. Among the clinical differences presented among COVID-19/TB co-infected patients, despite the association with HIV and lower clinical repercussions, only lower hemoglobin levels were associated with COVID-19/TB. Currently COVID19 COVID 19 COVID-1 (TB worldwide synergy presentation morbidity explored Thus epidemiological coinfection co casecontrol case control 2 laboratoryconfirmed confirmed COVID19/TB COVID19TB COVIDTB 19/TB coinfected infected group group. . city State Brazil 202 2022 p005 p 0 05 p≤0.05 coinfection, infection, controlgroup, controlgroup group, control-group outcome hand Creactive C reactive COVID19/TB. 19/TB. repercussions COVID1 1 COVID- 19TB 20 p00 p≤0.0 p0 p≤0. p≤0 p≤

Hot potassium carbonate (HPC) process aims to remove the CO2 present on synthesis gas. This removal is done in an absorption process, where takes place the reaction of CO2 with a K2CO3 solution. This reaction is slow and H3BO3 can be used to increase the rate of reaction. The rate-based model is the most suitable way to model the process. This approach uses different correlations to calculate important mass transfer and hydraulic parameters, such as: mass transfer coefficient, interfacial area, and liquid holdup. This paper aims to evaluate the performance of many correlations to represent the HPC process. An automatic procedure was developed to test a high number of equations, using MATLAB and Aspen Plus software. The best set of correlations was found after a comparison with industrial data. Correlations with errors less than 10% for the entire evaluated operating conditions were calculated for mass transfer coefficient and the interfacial area, as well as for liquid holdup. (HPC CO gas KCO K K2CO solution HBO H BO H3BO ratebased based parameters area holdup equations software data 10 1

Metallurgical waste and vermiculite are solid residues that have potential of utilization as filtering material. Nevertheless, they are commonly discarded. These materials have chemical sites like Si-O, Si-O-Si in vermiculite or have good ionic exchange properties like iron oxide compounds that can be used in adsorption processes. When these materials are combined with a synthetic blanket (OH, C=C, CO and C-H groups), it composes a filter layer with potential to be used in wastewater treatment. In this article, these materials were chemically treated and characterized by Thermogravimetry (TG), Differential Scanning Calorimetry (DSC), Fourier Transform Infrared Spectroscopy (FTIR) and coupled TG-FTIR. The results suggest that organic compound contamination was not found after chemical treatment, which could have remained over the unity operations in the Metallurgical processes. The thermal and acid treatments influenced a major formation of iron oxide formation, but its oxidation degree (FeO, Fe2O3, or Fe2O3.FeO) were dependent on the sample granulometry. The Vermiculite shows an irreversible chemical modification after thermal treatment. The characterization of these residues shows its potential use as material in filter construction. Hence, it is fundamental to minimize the environmental impacts as well as to diminish the production costs in wastewater treatment. Nevertheless discarded SiO, SiO Si O, O Si-O SiOSi processes OH, OH (OH CC C C=C CH H groups, groups , groups) treatment article TG, TG (TG) DSC, DSC (DSC) FTIR (FTIR TGFTIR. TGFTIR FTIR. TG-FTIR FeO, FeO (FeO Fe2O3 Fe Fe2O3.FeO Fe2O3FeO FeOFeO granulometry construction Hence (TG (DSC Fe2O

RESUMO: Neste estudo retrospectivo, são descritos os achados clínicos e anatomopatológicos das doenças fúngicas em cães e gatos no Nordeste do Brasil. Durante o período de estudo, foram revisados 6.827 exames histopatológicos (4.090 necropsias e 2.737 biópsias) de animais de companhia e diagnosticados 54 casos de infecções fúngicas. Destes, 32 casos foram diagnosticados em gatos e 22 em cães. A esporotricose foi a micose mais prevalente (19/54), seguida pela dermatofitose (9/54), criptococose (8/54), candidíase (7/54) e feo-hifomicose (4/54). Outras doenças tiveram dois casos cada, incluindo aspergilose, mucormicose e histoplasmose, enquanto a coccidioidomicose ocorreu uma vez. As micoses foram diagnosticadas por meio das lesões microscópicas associadas às características histomorfológicas do agente, evidenciadas pelas colorações de rotina e histoquímicas especiais, e ocasionalmente confirmadas pela imuno-histoquímica e cultivo microbiológico. Esse estudo retrospectivo demonstrou que apesar de incomuns, as doenças fúngicas são importantes causas de morte em cães e gatos da região, sendo os gatos a espécie mais afetada e a esporotricose, a micose mais prevalente. Os sinais clínicos estavam correlacionados com a porta de entrada da infecção, associados a lesões cutâneas localizadas ou disseminadas superficiais e profundas ou afetando órgãos parenquimatosos, especialmente em infecções sistêmicas. As lesões microscópicas eram caracterizadas principalmente por inflamação piogranulomatosa associada a estruturas fúngicas. Nos cães, as micoses ocorreram principalmente devido ao comprometimento imunológico secundária a coinfecção pelo vírus da cinomose canina. RESUMO Brasil 6827 6 827 6.82 4.090 4090 4 090 (4.09 2737 2 737 2.73 biópsias 5 Destes 3 19/54, 1954 19/54 , 19 (19/54) 9/54, 954 9/54 9 (9/54) 8/54, 854 8/54 8 (8/54) 7/54 754 7 (7/54 feohifomicose feo hifomicose 4/54. 454 4/54 . (4/54) cada aspergilose histoplasmose vez agente especiais imunohistoquímica imuno histoquímica microbiológico incomuns região infecção parenquimatosos sistêmicas canina 682 82 6.8 4.09 409 09 (4.0 273 73 2.7 195 19/5 1 (19/54 95 9/5 (9/54 85 8/5 (8/54 7/5 75 (7/5 45 4/5 (4/54 68 6. 4.0 40 0 (4. 27 2. 19/ (19/5 9/ (9/5 8/ (8/5 7/ (7/ 4/ (4/5 4. (4 (19/ (9/ (8/ (7 (4/ ( (19 (9 (8 (1

ABSTRACT: In this retrospective study, the clinical and anatomopathological findings of fungal diseases in dogs and cats in Northeastern Brazil are described. During the study period, 6,827 histopathological examinations (4,090 necropsies and 2,737 biopsies) of companion animals were reviewed, and fungal infections were diagnosed in 54 cases. Of these, 32 cases were diagnosed in cats and 22 in dogs. Sporotrichosis was the most prevalent mycosis (19/54), followed by dermatophytosis (9/54), cryptococcosis (8/54), candidiasis (7/54), and phaeohyphomycosis (4/54). Other diseases had two cases each, including aspergillosis, mucormycosis, and histoplasmosis, whereas coccidioidomycosis occurred once. Mycoses were diagnosed through microscopic lesions associated with the histomorphological characteristics of the agent, as evidenced by routine and special histochemical stains. They were occasionally confirmed by immunohistochemistry and microbiological cultivation. This retrospective study showed that despite being uncommon, fungal diseases are important causes of death in dogs and cats in the region, with cats being the most affected species and sporotrichosis being the most prevalent mycosis. Clinical signs were correlated with the portal of entry of the infection associated with localized or disseminated superficial and deep skin lesions or affecting parenchymal organs, especially in systemic infections. Microscopic lesions were mainly characterized by pyogranulomatous inflammation associated with fungal structures. In dogs, mycoses occurred mainly owing to an immunological impairment secondary to canine distemper virus co-infection. ABSTRACT described period 6827 6 827 6,82 4,090 4090 4 090 (4,09 2737 2 737 2,73 biopsies reviewed 5 these 3 19/54, 1954 19/54 , 19 (19/54) 9/54, 954 9/54 9 (9/54) 8/54, 854 8/54 8 (8/54) 7/54, 754 7/54 7 (7/54) 4/54. 454 4/54 . (4/54) each aspergillosis mucormycosis histoplasmosis once agent stains cultivation uncommon region organs structures coinfection. coinfection co infection. co-infection 682 82 6,8 4,09 409 09 (4,0 273 73 2,7 195 19/5 1 (19/54 95 9/5 (9/54 85 8/5 (8/54 75 7/5 (7/54 45 4/5 (4/54 68 6, 4,0 40 0 (4, 27 2, 19/ (19/5 9/ (9/5 8/ (8/5 7/ (7/5 4/ (4/5 4, (4 (19/ (9/ (8/ (7/ (4/ ( (19 (9 (8 (7 (1

ABSTRACT Management of agricultural production systems interferes with greenhouse gases (GHG) emissions, thereby altering physical, chemical, and biological attributes of soil; therefore, it is important to understand the relationship between soil attributes and GHG emissions. This study evaluated GHG emissions and their relationship with soil attributes in off-season soybean, maize, brachiaria and eucalyptus production systems. The experiment was carried out in Brejo, Maranhão, Brazil, with soybean ( Glycine max ), maize ( Zea mays ), brachiaria ( Urochloa ruzizienses ), and eucalyptus ( Eucalyptus grandis ). Fluxes of carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) were evaluated using air samples analyzed by gas chromatography. Soil attributes were ammonium and nitrate contents, total organic carbon, moisture, pH, density, total porosity, and water-filled pore space. N2O flux was 287.1 µg m-2 h -1 for eucalyptus cultivation, while areas cultivated with soybeans, maize and brachiaria had influxes of 46.7, 7.2, and 13.17 µg m-2 h-1, respectively. In the off-season, the highest emissions of N2O and CO2 were measured in eucalyptus areas due to soil moisture and porosity conditions provided by accumulation of litter on the soil surface. (GHG physical chemical therefore offseason off season Brejo Maranhão Brazil , ) . CO2, CO (CO2) CH4, CH4 CH (CH4) NO N O (N2O chromatography contents pH density waterfilled water filled space 2871 287 1 287. m2 m 2 m- - cultivation soybeans 467 46 7 46.7 72 7.2 1317 13 17 13.1 h1, h1 1, h-1 respectively offseason, season, surface (CO2 (CH4 28 4 46. 7. 131 13. h- (CO (CH