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Resumo O objetivo deste trabalho foi determinar os níveis de acidez para obter os atributos químicos do solo adequados à máxima produção de frutos de amoreiras-pretas cultivadas em solos ácidos submetidos a doses crescentes de calcário. Foram avaliadas as cultivares de amoreira-preta BRS Tupy, Brazos, Guarani e BRS Xavante nos solos Latossolo Vermelho Distroférico (LVdf) e Latossolo Vermelho distrófico (LVd), aos quais foram aplicadas quatro doses de calcário dolomítico (0, 1,5, 3,0 e 6,0 Mg ha-1). Foram avaliados o efeito da calagem sobre os atributos químicos do solo, em arranjo fatorial 2×4 (solos e doses de calcário), bem como o teor de nutrientes foliares e a produção de frutos, em arranjo fatorial 2×4×4 (solos, doses de calcário e cultivares). A produção máxima de frutos foi obtida com 3,3 Mg ha-1 de calcário dolomítico. As cultivares de amoreira-preta apresentaram alta demanda por Ca, Mg e saturação por bases e baixa tolerância ao alumínio nos solos. A partir de 3,3 Mg ha-1 de calcário dolomítico, a produção máxima de frutos de amoras-pretas cultivadas em solos ácidos é obtida com pH 5,6, saturação máxima tolerada de alumínio de 6%, concentração de Ca e Mg de 45,3 mmolc kg-1 e saturação por bases de 48,3%. amoreiraspretas amoreiras pretas amoreirapreta amoreira preta Tupy Brazos LVdf (LVdf LVd, LVd , (LVd) 0, 0 (0 15 1 5 1,5 30 3 3, 60 6 6, ha1. ha1 ha . ha-1) 24 2 4 2× calcário, calcário) 244 2×4× solos, cultivares. cultivares) 33 ha- amoraspretas amoras 56 5,6 6% 453 45 45, kg1 kg kg- 483 48 48,3% (LVd ( 1, 5, 48,3 48,

Abstract The objective of this work was to determine the acidity levels to obtain adequate soil chemical attributes for the maximum fruit yield of blackberry trees grown in acidic soils subjected to increasing limestone rates. The BRS Tupy, Brazos, Guarani, and BRS Xavante blackberry cultivars were evaluated on the Typic Hapludox (LVdf) and Rhodic Hapludox (LVd) soils, to which four rates of dolomitic limestone were applied (0, 1.5, 3.0, and 6.0 Mg ha-1). The effect of liming on soil chemical attributes, in a 2×4 factorial arrangement (soils and limestone rates), as well as leaf nutrient content and fruit yield, in a 2×4×4 factorial arrangement (soils, limestone rates, and cultivars), were evaluated. The maximum fruit yield was obtained with 3.3 Mg ha-1 dolomitic limestone. The blackberry cultivars showed a high demand for Ca, Mg, and base saturation and a low tolerance to aluminum in the soils. From 3.3 Mg ha-1 dolomitic limestone, the maximum fruit yield of blackberry trees grown in acidic soils is obtained with pH 5.6, maximum tolerated aluminum saturation of 6%, Ca and Mg concentration of 45.3 mmolc kg-1, and base saturation of 48.3%. Tupy Brazos Guarani LVdf (LVdf LVd (LVd 0, 0 (0 15 1 5 1.5 30 3 3.0 60 6 6. ha1. ha1 ha . ha-1) 24 2 4 2× , rates) 244 2×4× cultivars, cultivars) 33 3. ha- 56 5.6 6% 453 45 45. kg1, kg1 kg 1, kg-1 483 48 48.3% ( 1. 5. kg- 48.3 48.

https://doi.org/10.1590/s1678-3921.pab2024.v59.03398

Facial representation of paroxysmal hemicrania and associated temporomandibular disorder: a case report disorder
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Santos, Pamela Pessoa Maia dos

; Buosi, Juliana Araújo Oliveira

; Braga Neto, Pedro

; Chaves, Hellíada Vasconcelos

; Conti, Paulo César Rodrigues

; Fiamengui, Lívia Maria Sales Pinto

RGO - Revista Gaúcha de Odontologia

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2024, Volume 72 elocation e20240009

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO A Hemicrania Paroxística é uma cefalalgia autonômica trigeminal descrita como uma dor severa e estritamente unilateral, que ocorre em paroxismos na região orbital, supraorbital e/ou temporal. Uma mulher de 45 anos de idade apresentou-se a um especialista em dor orofacial, referindo uma cefaleia intensa, ardente, latejante, estritamente do lado direito, associada a sintomas autonómicos ipsilaterais e dor orofacial. A dor era sentida na região maxilar, seguida de dor que se estendia à cabeça. A avaliação interdisciplinar, aliada à resposta absoluta à indometacina e à normalidade em ressonância magnética cerebral, levou ao diagnóstico de hemicrania paroxística episódica primária com representação facial e dor miofascial dos músculos mastigatórios. Os médicos dentistas devem estar atentos à hemicrania paroxística com representação facial e à possibilidade de coexistência de Disfunção Temporomandibular, de modo a evitar diagnósticos incorretos e um tratamento inadequado. A hemicrania paroxística pode ser percebida inicialmente na face e pode estar associada à dor interparoxística. Nesses casos, é necessária uma anamnese e avaliação clínica eficientes, seguidas de abordagem interdisciplinar. unilateral orbital eou ou temporal 4 apresentouse apresentou orofacial intensa ardente latejante direito maxilar cabeça interdisciplinar cerebral mastigatórios Temporomandibular inadequado interparoxística casos eficientes

ABSTRACT Paroxysmal Hemicrania is a trigeminal autonomic cephalalgia described as a severe and strictly unilateral pain, which occurs in paroxysms at orbital, supraorbital and/ or temporal region. A 45-year-old woman presented to an orofacial pain specialist reporting severe, burning, throbbing, strictly right-sided headache associated to ipsilateral autonomic symptoms and orofacial pain. The pain was perceived on the maxillary region followed by pain spread to the head. Interdisciplinary evaluation, along with absolute responsiveness to indomethacin and normal Brain Magnetic Resonance imaging, led to the diagnosis of primary Episodic paroxysmal hemicrania with facial representation and myofascial pain of masticatory muscles. Dentists should be aware of paroxysmal hemicrania with facial representation and the possibility of temporomandibular disorder coexistence, in order to avoid misdiagnosis and inadequate management. Paroxysmal hemicrania may be first perceived on the face and may be associated with interparoxysmal pain. In these cases, efficient anamnesis and clinical evaluation followed by interdisciplinary approach is needed. orbital 45yearold yearold 45 year old burning throbbing rightsided right sided head imaging muscles coexistence management cases needed 4

https://doi.org/10.1590/1981-86372024000920220105

Natural Durability of Mimosa tenuiflora and Mimosa caesalpiniaefolia Woods: Two Species from the Brazilian Dry Forest Woods
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Braga, Rodolpho Stephan Santos

; Melo, Rafael Rodolfo de

; Pimenta, Alexandre Santos

; Garlet, Alencar

; Canto, Juliana Lorensi do

; Medeiros Neto, Pedro Nicó de

Floresta e Ambiente

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2024, Volume 31 N. 3 elocation e20240011

Abstract: En | Text: En | PDF: En

Abstract Knowledge of the characteristics and durability of every wood species is essential so it can be better directed for the correct harnessing. In a wood rot field test, this work aimed to determine the natural durability of timber species from the Brazilian dry forest, Mimosa tenuiflora and Mimosa caesalpiniaefolia . The slats were buried in the ground up to half their length and distributed in the field according to a completely randomized experimental design. Annual assessments were performed to determine the deterioration rate. Furthermore, mass loss and condensed tannin content were quantified. The condensed tannin content found for the species was 4.40% for M. caesalpiniaefolia and 3.99% for M. tenuiflora . The results of 3 years of evaluation of the test make it possible to understand that both species presented durable wood, where M. caesalpiniaefolia presented a deterioration rate of 77.27%, while M. tenuiflora presented 66.27%, making them of high natural durability. harnessing forest design Furthermore quantified 440 4 40 4.40 M 399 99 3.99 7727 77 27 77.27% 6627 66 66.27% 44 4.4 39 9 3.9 772 7 2 77.27 662 6 66.27 4. 3. 77.2 66.2 77. 66.

https://doi.org/10.1590/2179-8087-floram-2024-0011

Accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with low education and mild cognitive impairment: results of a cross-sectional study in two metropolitan areas of Northeast Brazil ACER ACE R (ACE-R impairment crosssectional cross sectional
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Passinho, Jhule Silva

; Tavares-Júnior, José Wagner Leonel

; Sudo, Felipe Kenji

; Bittencourt, Lays

; Alves, Candida Helena Lopes

; Siqueira-Neto, José Ibiapina

; Braga Neto, Pedro

; Alves, Gilberto Sousa

Jornal Brasileiro de Psiquiatria

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2024, Volume 73 N. 2 elocation e20230035

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo Determinar a acurácia diagnóstica do Exame Cognitivo de Addenbrooke (ACE-R) para idosos com baixa escolaridade, sem demência, em duas capitais no nordeste do Brasil, comparando a sujeitos com CCL. Métodos Foram coletados 100 participantes a partir de uma avaliação neurológica e psiquiátrica prévia, sendo submetidos aos ACE-R posteriormente. Dentre eles, 18 sujeitos com comprometimento cognitivo leve amnéstico (aCCL), 22 com comprometimento cognitivo leve não amnéstico (naCCL) e 60 controles saudáveis. Resultados Os pontos de acurácia do ACE-R foram considerados excelentes para a comparação entre controles e naCCL [Área sob a curva (AUC) = 0,919)] e controles e aCCL (AUC= 0,921); por outro lado, foi relatada uma baixa acurácia para a comparação entre aCCL e naCCL (AUC= 0,578). Conclusões Os achados dão suporte à necessidade de estudos estabelecendo pontos de corte confiáveis para a avaliação cognitiva de idosos com baixa escolaridade e declínio cognitivo sem demência, levando-se em consideração variáveis ecológicas e regionais. ACER ACE R (ACE-R demência Brasil CCL 10 prévia posteriormente eles 1 aCCL, , (aCCL) 2 (naCCL 6 saudáveis Área AUC (AUC 0,919 0919 0 919 0,919) AUC= 0,921 0921 921 0,921) lado 0,578. 0578 0,578 . 578 0,578) levandose levando se regionais (aCCL 0,91 091 91 0,92 092 92 057 0,57 57 0,9 09 9 05 0,5 5 0,

ABSTRACT Objective To determine the diagnostic accuracy of the Addenbrooke’s Cognitive Examination (ACE-R) for older adults with low education, without dementia, in two capitals in northeastern Brazil, compared to subjects with MCI. Methods 100 participants were collected from a previous neurological and psychiatric evaluation and were subsequently subjected to the ACE-R. Among them, 18 subjects with amnestic mild cognitive impairment (aMCI), 22 with non-amnestic mild cognitive impairment (naMCI), and 60 healthy controls. Results Optimal ACE-R accuracy yielded excellent values for the comparison between controls and naMCI [Area Under the Curve (AUC) = 0.919)] and controls and aMCI (AUC= 0.921); conversely, very fair accuracy was reported for the comparison between aMCI and naMCI (AUC= 0.578). Conclusions These findings support establishing reliable cutoff scores for cognitive assessment of elderlies with low schooling and cognitive decline, not dementia, taking into consideration ecological and regional variables. Addenbrookes Addenbrooke s ACER ACE R (ACE-R education dementia Brazil MCI 10 ACER. R. them 1 aMCI, , (aMCI) 2 nonamnestic non naMCI, (naMCI) 6 Area AUC (AUC 0.919 0919 0 919 0.919) AUC= 0.921 0921 921 0.921) conversely 0.578. 0578 0.578 . 578 0.578) decline variables (aMCI (naMCI 0.91 091 91 0.92 092 92 057 0.57 57 0.9 09 9 05 0.5 5 0.

https://doi.org/10.1590/0047-2085-2023-0035

Correlation between ABO blood type, susceptibility to SARS-CoV-2 infection and COVID-19 disease severity: A systematic review type SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- COVID19 COVID 19 COVID-1 severity SARS-CoV COVID1 1 COVID-
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Soares, Danyela Martins Bezerra

; Araújo, David Augusto Batista Sá

; Souza, Jorge Luiz de Brito de

; Maurício, Rebeca Bessa

; Soares, Emanuela Martins Bezerra

; Alves Neto, Franklin de Castro

; Pinheiro, Maria Suelly Nogueira

; Gama, Vitor Carneiro de Vasconcelos

; Braga Neto, Pedro

; Nóbrega, Paulo Ribeiro

; Aragão, Gislei Frota

Hematology, Transfusion and Cell Therapy

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dec 2023, Volume 45 N. 4 Pages 483 - 494

Abstract: En | Text: En | PDF: En

ABSTRACT Objectives: To verify the association between the ABO blood type and the risk of SARS-CoV-2 infection and COVID-19 disease severity. Methods: This review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), using the 2020 PRISMA Checklist and flow diagram, and articles selected for review were analyzed using the Newcastle-Ottawa Quality Rating Scale. The research question was: "Would the ABO blood group influence the risk of infection and clinical course of patients infected with SARS-CoV-2?", The following databases were used: Embase, PubMed, Virtual Health Library (VHL), Web of Science, Science-Direct and Scopus. The protocol for this review was registered in the Prospective Register of Systematic Reviews (PROSPERO), number CRD42021245945. Results: We found 798 articles across PubMed, Embase, Scopus, Web of Science, Science Direct and Virtual Health Library and 54 articles were included in the final analysis. Among 30 studies evaluating the risk of COVID-19 infection, 21 found significant correlations with ABO blood groups, 14 of them revealing an increased risk in blood group A and 15 studies showing a decreased risk in blood group O. Most studies found no significant correlation with disease severity or mortality. Conclusion: The qualitative assessment of available information suggests that blood group A may be a risk factor for COVID-19 infection and that blood group O may have a protective effect. We were unable to determine a clear association between the ABO blood group and mortality. These conclusions are based on highly heterogenous evidence. Objectives SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- COVID19 COVID 19 COVID-1 Methods MetaAnalyses Meta Analyses PRISMA, , (PRISMA) 202 diagram NewcastleOttawa Newcastle Ottawa Scale Would SARSCoV2, SARS-CoV-2?" used Embase PubMed VHL, VHL (VHL) ScienceDirect Scopus PROSPERO, PROSPERO (PROSPERO) CRD42021245945 CRD Results 79 5 analysis 3 groups 1 mortality Conclusion effect evidence SARS-CoV COVID1 COVID- (PRISMA 20 SARS-CoV-2? (VHL (PROSPERO CRD4202124594 7 CRD420212459 CRD42021245 CRD4202124 CRD420212 CRD42021 CRD4202 CRD420 CRD42 CRD4

https://doi.org/10.1016/j.htct.2022.11.001

Sjogren's syndrome: a neurological perspective Sjogrens Sjogren s syndrome
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Barsottini, Orlando Grazianni Povoas

; Moraes, Marianna Pinheiro Moraes de

; Fraiman, Pedro Henrique Almeida

; Marussi, Victor Hugo Rocha

; Souza, Alexandre Wagner Silva de

; Braga Neto, Pedro

; Spitz, Mariana

Arquivos de Neuro-Psiquiatria

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dec 2023, Volume 81 N. 12 Pages 1077 - 1083

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A síndrome de Sjogren (SS) é uma doença autoimune complexa caracterizada pela infiltração linfocítica das glândulas salivares e lacrimais, resultando em sintomas sicca. Além disso, a SS apresenta manifestações neurológicas que afetam significativamente o sistema nervoso. Esta revisão tem como objetivo fornecer uma visão abrangente dos aspectos neurológicos da SSj, abordando tanto o envolvimento do sistema nervoso periférico quanto do central, com ênfase no diagnóstico, tratamento e prognóstico. (SS lacrimais sicca disso SSj central diagnóstico prognóstico

Abstract Sjogren's syndrome (SS) is a complex autoimmune disease characterized by lymphocytic infiltration of salivary and lacrimal glands, resulting in sicca symptoms. Additionally, SS presents with neurological manifestations that significantly impact the nervous system. This review aims to provide a comprehensive overview of the neurological aspects of SSj, covering both the peripheral and central nervous system involvement, while emphasizing diagnosis, treatment, and prognosis. Sjogrens Sjogren s (SS glands symptoms Additionally SSj involvement diagnosis treatment prognosis

https://doi.org/10.1055/s-0043-1777105

Movement disorders in hereditary spastic paraplegias
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Pedroso, Jose Luiz

; Vale, Thiago Cardoso

; Freitas, Julian Letícia de

; Araújo, Filipe Miranda Milagres

; Meira, Alex Tiburtino

; Braga Neto, Pedro

; França Junior, Marcondes C.

; Tumas, Vitor

; Teive, Hélio A. G.

; Barsottini, Orlando G. P.

Arquivos de Neuro-Psiquiatria

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nov 2023, Volume 81 N. 11 Pages 1000 - 1007

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Antecedentes As paraplegias espásticas hereditárias ou familiares (SPG) compreendem um grupo de doenças geneticamente e fenotipicamente heterogêneas caracterizadas por degeneração progressiva dos tratos corticospinais. As formas complicadas evoluem com vários outros sinais e sintomas neurológicos, incluindo distúrbios do movimento e ataxia. Objetivo Resumir as descrições clínicas de SPG que se manifestam com distúrbios do movimento ou ataxias para auxiliar o clínico na tarefa de diagnosticar essas doenças. Métodos Realizamos uma revisão da literatura, incluindo relatos de casos, séries de casos, artigos de revisão e estudos observacionais publicados em inglês até dezembro de 2022. Resultados O parkinsonismo juvenil ou de início precoce com resposta variável à levodopa foi relatado principalmente em SPG7 e SPG11. A distonia pode ser observada em pacientes com SPG7, SPG11, SPG22, SPG26, SPG35, SPG48, SPG49, SPG58, SPG64 e SPG76. O tremor não é um achado frequente em pacientes com SPG, mas é descrito em diferentes tipos de SPG, incluindo SPG7, SPG9, SPG11, SPG15 e SPG76. A mioclonia é raramente descrita em SPG, afetando pacientes com SPG4, SPG7, SPG35, SPG48 e SPOAN (paraplegia espástica, atrofia óptica e neuropatia). SPG4, SPG6, SPG10, SPG27, SPG30 e SPG31 podem raramente apresentar ataxia com atrofia cerebelar. E SPG autossômico recessivo, como SPG7 e SPG11, também pode apresentar ataxia. Conclusão Indivíduos com SPG podem apresentar diferentes formas de distúrbios do movimento, como parkinsonismo, distonia, tremor, mioclonia e ataxia. O distúrbio específico do movimento na manifestação clínica de um paciente com SPG pode ser uma pista clínica para o diagnóstico. (SPG corticospinais neurológicos literatura casos 2022 SPG11 SPG22 SPG26 SPG35 SPG49 SPG58 SPG6 SPG76 SPG9 SPG1 SPG4 paraplegia espástica neuropatia. neuropatia . neuropatia) SPG10 SPG27 SPG3 cerebelar recessivo diagnóstico 202 SPG2 SPG5 20 2

Abstract Background Hereditary or familial spastic paraplegias (SPG) comprise a group of genetically and phenotypically heterogeneous diseases characterized by progressive degeneration of the corticospinal tracts. The complicated forms evolve with other various neurological signs and symptoms, including movement disorders and ataxia. Objective To summarize the clinical descriptions of SPG that manifest with movement disorders or ataxias to assist the clinician in the task of diagnosing these diseases. Methods We conducted a narrative review of the literature, including case reports, case series, review articles and observational studies published in English until December 2022. Results Juvenile or early-onset parkinsonism with variable levodopa-responsiveness have been reported, mainly in SPG7 and SPG11. Dystonia can be observed in patients with SPG7, SPG11, SPG22, SPG26, SPG35, SPG48, SPG49, SPG58, SPG64 and SPG76. Tremor is not a frequent finding in patients with SPG, but it is described in different types of SPG, including SPG7, SPG9, SPG11, SPG15, and SPG76. Myoclonus is rarely described in SPG, affecting patients with SPG4, SPG7, SPG35, SPG48, and SPOAN (spastic paraplegia, optic atrophy, and neuropathy). SPG4, SPG6, SPG10, SPG27, SPG30 and SPG31 may rarely present with ataxia with cerebellar atrophy. And autosomal recessive SPG such as SPG7 and SPG11 can also present with ataxia. Conclusion Patients with SPG may present with different forms of movement disorders such as parkinsonism, dystonia, tremor, myoclonus and ataxia. The specific movement disorder in the clinical manifestation of a patient with SPG may be a clinical clue for the diagnosis. (SPG tracts symptoms literature reports series 2022 earlyonset early onset levodoparesponsiveness levodopa responsiveness reported SPG22 SPG26 SPG35 SPG48 SPG49 SPG58 SPG6 SPG76 SPG9 SPG15 SPG4 paraplegia atrophy neuropathy. neuropathy . neuropathy) SPG10 SPG27 SPG3 SPG1 dystonia tremor diagnosis 202 SPG2 SPG5 20 2

https://doi.org/10.1055/s-0043-1777005

Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients Parkinsons Parkinson s
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Lima, Danielle Pessoa

; Bonfadini, Janine de Carvalho

; Carneiro, Alexandre Henrique Silva

; Almeida, Samuel Brito de

; Viana Júnior, Antonio Brazil

; Nogueira e Silva, Ana Cecília

; Roriz Filho, Jarbas de Sá

; Braga Neto, Pedro

Dementia & Neuropsychologia

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2023, Volume 17 elocation e20220084

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO. A prevalência de comprometimento cognitivo na doença de Parkinson (DP) é de cerca de 20 a 60%. O Miniexame do Estado Mental (MEEM) é o teste de rastreio cognitivo mais utilizado. Objetivo: Avaliar a influência de características clínicas e demográficas, especificamente a escolaridade, no escore do MEEM em pacientes com DP de uma amostra do nordeste brasileiro. Métodos: Realizamos um estudo transversal com 198 pacientes com DP em um ambulatório de Distúrbios do Movimento em Fortaleza. Os participantes foram avaliados por história clínica detalhada, estadiamento modificado de Hoehn e Yahr (HY), escala de depressão geriátrica (EDG) e MEEM. Resultados: Encontramos 68% dos pacientes com escores do MEEM abaixo dos limiares brasileiros baseados em estudo de Brucki et al. (2003). Houve diferença estatisticamente significativa na análise bivariada entre a escolaridade e a classificação de corte para o MEEM. Mais anos de escolaridade foram associados a mais pacientes com pontuação abaixo do limiar. Constatamos que 75, 68,8 e 79,7% dos indivíduos com mais de 11, nove a 11 e quatro a oito anos de escolaridade, respectivamente, estavam abaixo dos limiares sugeridos pelo estudo brasileiro de Brucki et al. (2003). A EDG e a idade correlacionaram-se negativamente com o MEEM total e todos os seus domínios. Não houve correlação entre a duração da doença e o MEEM. Indivíduos com alucinações tiveram pontuações mais baixas. Conclusão: A maioria da amostra apresentou desempenho inferior aos limiares, mas não houve grupo controle e nem teste neuropsicológico neste estudo. Mais estudos no nordeste do Brasil são necessários para revisar os valores de corte do MEEM. RESUMO (DP 2 60 60% (MEEM utilizado Objetivo demográficas Métodos 19 Fortaleza detalhada HY, HY , (HY) (EDG Resultados 68 al 2003. 2003 . (2003) limiar 75 688 8 68, 797 79 7 79,7 1 respectivamente correlacionaramse correlacionaram se domínios baixas Conclusão 6 (HY 200 (2003 79, (200 (20 (2 (

ABSTRACT. The prevalence of cognitive impairment in Parkinson's disease (PD) is about 20% to 60%. The Mini-Mental Status Examination (MMSE) is the most used cognitive screening test. Objective: To evaluate the influence of clinical and demographic characteristics, specifically the education level, on the MMSE score in PD patients of a northeast Brazilian sample. Methods: We performed a cross-sectional study of 198 PD patients at a Movement Disorders outpatient clinic in Fortaleza, CE, Brazil. Participants were assessed by detailed clinical history, modified Hoehn and Yahr staging (HY), geriatric depression scale (GDS) and MMSE. Results: We found that 68% of patients had MMSE scores below the Brazilian thresholds, which were based in Brucki et al. study (2003). There was a statistically significant difference in the bivariate analysis between educational level and cut-off classification for MMSE. More years of formal schooling were associated with more patients scoring below threshold. We found that 75%, 68.8%, and 79.7% of individuals with more than 11, 9 to 11, and 4 to 8 years of formal schooling, respectively, were below the suggested Brazilian Brucki's threshold. GDS and age were negatively correlated with total MMSE and all its domains. There was no correlation between disease duration and MMSE. Subjects with hallucinations had lower scores. Conclusion: Most of the sample had lower performance according to Brazilian thresholds, but there was no control group and no neuropsychological test in this study. Further studies in northeast Brazil are needed to review MMSE cut-off values. ABSTRACT Parkinsons Parkinson s (PD 20 60 60% MiniMental Mini Mental (MMSE Objective characteristics Methods crosssectional cross sectional 19 Fortaleza CE history HY, HY , (HY) (GDS Results 68 thresholds al 2003. 2003 . (2003) cutoff cut off threshold 75 75% 688 68.8% 797 79 7 79.7 11 respectively Bruckis domains Conclusion values 2 6 1 (HY 200 (2003 68.8 79. (200 68. (20 (2 (

https://doi.org/10.1590/1980-5764-dn-2022-0084

10.

Associação entre a capacidade funcional, transtorno do sono e nível de atividade física em indivíduos com doença de Parkinson durante o período de pandemia de covid-19: um estudo transversal funcional covid19 covid 19 covid-19 covid1 1 covid-1 covid-
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Alencar, Madeleine Sales de

; Lima, Danielle Pessoa

; Gomes, Vlademir Carneiro

; Viana Júnior, Antonio Brazil

; Braga Neto, Pedro

; Lima, Lidiane Andréa Oliveira

Revista Brasileira de Geriatria e Gerontologia

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2023, Volume 26 elocation e220167

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo Avaliar o nível de atividade física, considerando as condições sociodemográficas, clínicas e funcionais, de pessoas idosas com Doença de Parkinson (DP). Método Foi realizado um estudo transversal a partir dos seguintes dados: nível de atividade física (International Physical Activity Questionnaire versão curta - IPAQ curto), transtornos do sono, queixa cognitiva, tempo de doença, grau de dependência para realizar atividades básicas do dia a dia pela escala Schwab & England (S & E) de indivíduos idosos com DP atendidos em um serviço de saúde terciário, durante a pandemia da covid-19. Regressão de Poisson, teste U de Mann-Whitney e teste t de Student foram utilizados para análise estatística. Resultados A cada 10 pontos de elevação na escala de S & E, a razão de prevalência de ser ativo foi maior em 1,04 (IC 95% 1,01 – 1,08) e quem não referiu transtorno de sono teve razão de prevalência de 1,17 (IC95% 1,02-1,34) vez maior de ser ativo. Indivíduos com DP inativos eram mais velhos e tinham maior tempo de doença. Conclusão Ênfase deve ser dada a capacidade funcional e ao sono de indivíduos com DP para o manejo adequado do nível de AF em períodos de restrição social. sociodemográficas funcionais DP. . (DP) dados International curto, curto , curto) cognitiva doença E terciário covid19. covid19 covid 19. 19 covid-19 Poisson MannWhitney Mann Whitney estatística 1 104 04 1,0 IC 95 101 01 1,08 108 08 117 17 1,1 IC95% IC95 (IC95 1,021,34 102134 1,02 1,34 02 34 1,02-1,34 social (DP covid1 covid-1 0 1, 9 11 IC9 (IC9 021 1,021,3 10213 102 134 1,3 3 1,02-1,3 covid- 1,021, 1021 13 1,02-1, 1,021 1,02-1 1,02-

Abstract Objective To assess the level of exercise of older people with Parkinson's disease (PD), taking into account sociodemographic, clinical, and functional characteristics. Method A cross-sectional study was carried out based on the following data: level of physical activity (International Physical Activity Questionnaire short version - short IPAQ), sleep disorders, cognitive complaints, duration of illness, degree of dependence to perform basic daily activities through Schwab & England (S&E) scale of older individuals with PD treated at a tertiary health service during the covid-19 pandemic. Poisson regression, Mann-Whitney U test and Student's t test were used for statistical analysis. Results The prevalence ratio of being active increased by 1.04 (95% CI 1.01 - 1.08) for every 10 points of elevation on the S&E scale, whereas those who did not report sleep difficulties had a prevalence ratio of 1.17 (95% CI 1.02-1.34) times greater to be active. Inactive individuals with PD were older and had longer disease duration. Conclusion Emphasis should be given to the functional capacity and sleep of individuals with PD for the adequate management of the PA level in periods of social restriction. Parkinsons Parkinson s PD, , (PD) sociodemographic clinical characteristics crosssectional cross sectional data International IPAQ, IPAQ IPAQ) disorders complaints illness SE S E (S&E covid19 covid 19 covid-1 pandemic regression MannWhitney Mann Whitney Students Student analysis 104 1 04 1.0 95% 95 (95 101 01 1.08 108 08 117 17 1.1 1.021.34 102134 1.02 1.34 02 34 1.02-1.34 restriction (PD covid1 covid- 0 1. 9 (9 11 021 1.021.3 10213 102 134 1.3 3 1.02-1.3 ( 1.021. 1021 13 1.02-1. 1.021 1.02-1 1.02-

https://doi.org/10.1590/1981-22562023026.220167.pt

11.

Effect of speech therapy on quality of life in patients with spinocerebelar ataxia type 3
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Diaféria, Giovana

; Bommarito, Silvana

; Braga Neto, Pedro

; Park, Sung Woo

; Padovani, Marina

; Haddad, Fernanda

; Haddad, Leonardo

; Voos, Mariana Callil

; Chien, Hsin Fen

; Pedroso, José Luiz

; Barsottini, Orlando

Arquivos de Neuro-Psiquiatria

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oct 2022, Volume 80 N. 10 Pages 1017 - 1025

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Antecedentes Indivíduos com ataxia espinocerebelar tipo 3 (AEC3) apresentam distúrbios da comunicação e deterioração da deglutição e, consequentemente, na qualidade de vida (QV). Objetivo Avaliar o impacto de um programa de reabilitação fonoaudiológica na QV em pacientes com AEC3. Métodos Todos os participantes foram alocados aleatoriamente em dois grupos, um grupo intervenção que recebeu terapia fonoaudiológica (GTF) e um grupo controle (GC). As pontuações das escalas: International Cooperative Ataxia Rating Scale (ICARS) foram 32,4 ± 20,2 e da Scale for the Assessment and Rating of Ataxia (SARA) foram 11,8 ± 8,0. A intervenção consistiu em um programa de reabilitação fonoaudiológica de 12 sessões composto por exercícios de fortalecimento oral, faríngeo e laríngeo - denominados ATAXIA - Terapia Miofuncional Orofacial e Vocal (A-TMOV). Todos foram submetidos a avaliações pré e pós-intervenção por meio dos protocolos World Health Organization's Quality of Life (WHOQOL-BREF), Vivendo com Disartria (VcD), Quality of Life in Swallowing Disorders (SWAL-QOL) e Food Assessment Tool (EAT-10). Resultados A amostra foi composta por 48 pacientes com AEC3 (25 no GTF e 23 no GC), média de idade 47,1 ± 11,4anos; média de idade de início dos sintomas 36,9 ± 11,3anos; duração da doença 11,9 ± 13,3anos. Após intervenção de três meses, houve mudanças significativas na QV no GTF em comparação com o GC quando avaliado pelo VcD (179,12 ± 62,55 versus129,88 ± 51,42, p < 0,001), SWAL-QOL (869,43 ± 153,63 versus 911,60 ± 130,90, p = 0,010), EAT-10 (5,16 ± 7,55 versus 2,08 ± 3,85, p = 0,018). Conclusões Pacientes com AEC3 devem receber terapia fonoaudiológica contínua como parte do programa A-TMOV, pois a terapia ajuda a melhorar a dificuldade de deglutição e a disartria. AEC (AEC3 consequentemente QV. . (QV) grupos (GTF GC. (GC) escalas ICARS (ICARS 324 32 4 32, 202 20 2 20, SARA (SARA 118 11 8 11, 80 0 8,0 1 oral ATMOV. ATMOV TMOV (A-TMOV) pósintervenção pós Organizations Organization s WHOQOLBREF, WHOQOLBREF WHOQOL BREF , (WHOQOL-BREF) VcD, (VcD) SWALQOL SWAL QOL (SWAL-QOL EAT10. EAT10 EAT 10 (EAT-10) 25 (2 GC, GC) 471 47 47, 11,4anos 114anos anos 4anos 369 36 9 36, 11,3anos 113anos 3anos 119 133anos 13 13,3anos meses 179,12 17912 179 (179,1 6255 62 55 62,5 versus12988 versus129 88 versus129,8 5142 51 42 51,42 0,001, 0001 0,001 001 0,001) 869,43 86943 869 43 (869,4 15363 153 63 153,6 91160 911 60 911,6 13090 130 90 130,90 0,010, 0010 0,010 010 0,010) EAT-1 5,16 516 5 16 (5,1 755 7 7,5 208 08 2,0 385 85 3,85 0,018. 0018 0,018 018 0,018) ATMOV, TMOV, A-TMOV disartria (AEC (QV (GC 8, (A-TMOV (WHOQOL-BREF (VcD EAT1 (EAT-10 ( 179,1 1791 17 (179, 625 6 62, versus1298 versus12 versus129, 514 51,4 000 0,00 00 869,4 8694 86 (869, 1536 15 153, 9116 91 911, 1309 130,9 0,01 01 EAT- 5,1 (5, 75 7, 2, 38 3,8 (EAT-1 179, (179 versus1 51, 0,0 869, (869 130, 5, (5 3, (EAT- (17 0, (86 (EAT (1 (8

Abstract Background Individuals with spinocerebellar ataxia type 3 (SCA3) present communication and swallowing disorders, and consequent deterioration in quality of life (QOL). Objective To evaluate the impact of a speech therapy rehabilitation program on the QOL of patients with SCA3. Methods All participants were randomly assigned to two groups, an intervention group receiving speech therapy (STG) and a control group (CG). The International Cooperative Ataxia Rating Scale scores were 32.4 ± 20.2, and the Scale for the Assessment and Rating of Ataxia scores were 11.8 ± 8.0. The intervention consisted of a 12-session speech therapy rehabilitation program with oral, pharyngeal, and laryngeal strengthening exercises—the so-called ATAXIA–Myofunctional Orofacial and Vocal Therapy (A-MOVT). They all were submitted to pre- and postintervention evaluations using the World Health Organization's Quality of Life (WHOQOL-BREF) assessment, as well as the Living with Dysarthria (LwD), Quality of Life in Swallowing Disorders (SWAL-QOL), and Food Assessment Tool (EAT-10). Results The study sample consisted of 48 patients with SCA3 (STG = 25; CG = 23), mean age was 47.1 ± 11.4 years; mean age at symptom onset was 36.9 ± 11.3 years; disease duration was 11.9 ± 13.3 years. After the 3-month intervention, there were significant changes in the QOL in the STG compared with the CG, when assessed by the LwD (179.12 ± 62.55 vs. 129.88 ± 51.42, p < 0.001), SWAL-QOL (869.43 ± 153.63 vs. 911.60 ± 130.90, p = 0.010), and EAT-10 (5.16 ± 7.55 vs. 2.08 ± 3.85, p = 0.018). Conclusions Patients with SCA3 should receive continuous speech therapy as part of the A-MOVT program, because therapy helps to improve difficulty swallowing and dysarthria. SCA (SCA3 disorders QOL. . (QOL) groups CG. (CG) 324 32 4 32. 202 20 2 20.2 118 11 8 11. 80 0 8.0 12session session 12 oral pharyngeal exercisesthe exercises socalled so called ATAXIAMyofunctional ATAXIA Myofunctional AMOVT. AMOVT A MOVT (A-MOVT) pre Organizations Organization s WHOQOLBREF WHOQOL BREF (WHOQOL-BREF assessment LwD, , (LwD) SWALQOL, SWALQOL SWAL (SWAL-QOL) EAT10. EAT10 EAT 10 (EAT-10) 25 23, 23 23) 471 47 1 47. 114 years 369 36 9 36. 113 119 133 13 13. 3month month 179.12 17912 179 (179.1 6255 62 55 62.5 vs 12988 129 88 129.8 5142 51 42 51.42 0.001, 0001 0.001 001 0.001) 869.43 86943 869 43 (869.4 15363 153 63 153.6 91160 911 60 911.6 13090 130 90 130.90 0.010, 0010 0.010 010 0.010) EAT-1 5.16 516 5 16 (5.1 755 7 7.5 208 08 2.0 385 85 3.85 0.018. 0018 0.018 018 0.018) dysarthria (SCA (QOL (CG 20. 8. (A-MOVT (LwD (SWAL-QOL EAT1 (EAT-10 179.1 1791 17 (179. 625 6 62. 1298 129. 514 51.4 000 0.00 00 869.4 8694 86 (869. 1536 15 153. 9116 91 911. 1309 130.9 0.01 01 EAT- 5.1 (5. 75 7. 2. 38 3.8 (EAT-1 179. (179 51. 0.0 869. (869 130. 5. (5 3. (EAT- (17 0. (86 ( (EAT (1 (8

https://doi.org/10.1055/s-0042-1755203

12.

Telehealth for Parkinson disease patients during the COVID-19 pandemic: the TeleParkinson study COVID19 COVID 19 COVID-1 pandemic COVID1 1 COVID-
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Lima, Danielle Pessoa

; Gomes, Vlademir Carneiro

; Viana Júnior, Antonio Brazil

; Assis, Francisco Mateus Carvalho de

; Oliveira, Pedro Henrique Avelino

; Cunha, Letícia Chaves Vieira

; Braga, Isabelly Cavalcante

; Marques, Miriam Lindsay Silva

; Assunção, Jézica de Sousa

; Damasceno, Adeline Louise Lopes

; Barbosa, Ana Lara Guerra

; Moreira, Arthur Holanda

; Rocha, Maria Eduarda Quidute Arrais

; Porto, Maria Eduarda Mendes Pontes

; Chaves, Érica Carneiro Barbosa

; Oliveira, Liliane Maria de

; Roriz Filho, Jarbas de Sá

; Sobreira Neto, Manoel Alves

; Braga Neto, Pedro

Arquivos de Neuro-Psiquiatria

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oct 2022, Volume 80 N. 10 Pages 1026 - 1035

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Antecedentes A telemedicina permite que pacientes com doença de Parkinson (DP) superem barreiras físicas para acessar serviços de saúde e aumenta a acessibilidade para pessoas com mobilidade reduzida. Objetivo Investigar indicadores de viabilidade de uma intervenção em telessaúde para pacientes com DP, incluindo recrutamento, atendimento, aderência, problemas técnicos, satisfação e benefícios nos níveis de atividade física e sono. Métodos Foi conduzido um estudo de centro e braço únicos baseado em consultas por telessaúde com utilização do WhatsApp (Meta Platforms, Inc., Menlo Park, CA, EUA). Foram calculados indicadores de viabilidade como desfechos primários. Resultados As taxas de recrutamento, atendimento e problemas técnicos foram 61,3%, 90,5% e 13,3%, respectivamente, com bons escores de aceitação e satisfação com a intervenção. A intervenção melhorou os níveis de atividade física, incluindo o número de passos por pelo menos 10 minutos contínuos (p = 0,009) e o número de atividades intensas e moderadas com duração de pelo menos 10 minutos contínuos (p = 0,001). O Índice de Qualidade do Sono de Pittsburgh melhorou nos seguintes componentes: duração percebida do sono (p < 0,001) e escore total (p < 0,001). A média do tempo de viagem médio poupado foi de 289,6 minutos, e a economia financeira foi de R$ 106,67 reais (por volta de USD 18; quase 10% do salário mínimo atual do Brasil). Conclusões As consultas por vídeo provaram ser viáveis e efetivas, com impacto positivo nos níveis de atividade física e sono de pacientes com DP. DP (DP reduzida recrutamento aderência Meta Platforms Inc Inc. Park CA EUA. EUA . EUA) primários 613 61 3 61,3% 905 90 5 90,5 133 13 13,3% respectivamente 1 p 0,009 0009 0 009 0,001. 0001 0,001 001 componentes 2896 289 6 289, R 10667 106 67 106,6 18 Brasil. Brasil Brasil) efetivas 61,3 9 90, 13,3 0,00 000 00 28 1066 106, 61, 13, 0,0 2 0,

Abstract Background Telemedicine allows Parkinson disease (PD) patients to overcome physical barriers to access health care services and increases accessibility for people with mobility impairments. Objective To investigate the feasibility indicators of a telehealth intervention for PD patients, including patient recruitment, attendance, technical issues, satisfaction, and benefits on levels of physical activity and sleep. Methods We conducted a single-center, single-arm study of telehealth video consultations using WhatsApp (Meta Platforms, Inc., Menlo Park, CA, USA). Also, we collected the feasibility indicators as the primary endpoints. All the patients in the study were previously evaluated in person by the same team. Results Patient recruitment, attendance, and technical issues rates were 61.3%, 90.5%, and 13.3%, respectively, with good scores of patient acceptance and satisfaction with the study intervention. The telehealth intervention improved physical activity, including the number of walks for at least 10 continuous minutes (p = 0.009) and the number of moderate-intensity activities lasting at least 10 continuous minutes (p = 0.001). The Pittsburgh sleep quality index (PSQI) scores also improved for one of its components: perceived sleep duration (p < 0.001) and for total Pittsburgh score (p < 0,001). The average travel time saving was 289.6 minutes, and money-saving was R$106.67 (around USD 18; almost 10% of the current minimum wage in Brazil). Conclusions Direct-to-patient telehealth video consultations proved to be feasible and effective and had a positive impact on physical activity levels and sleep in PD patients. (PD impairments recruitment attendance singlecenter, singlecenter single center, center single-center singlearm arm Meta Platforms Inc Inc. Park CA USA. USA . USA) Also endpoints team 613 61 3 61.3% 905 90 5 90.5% 133 13 13.3% respectively 1 p 0.009 0009 0 009 moderateintensity moderate intensity 0.001. 0001 0.001 001 PSQI (PSQI components 0,001. 0,001 0,001) 2896 289 6 289. moneysaving money R10667 R 106 67 R$106.6 around 18 Brazil. Brazil Brazil) Directtopatient Direct 61.3 9 90.5 13.3 0.00 000 00 0,00 28 R1066 R$106. 61. 90. 13. 0.0 0,0 2 R106 R$106 0. 0, R10 R$10 R1 R$1 R$

https://doi.org/10.1055/s-0042-1758751

13.

An overview of dysphagia rehabilitation for stroke patients
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Matos, Klayne Cunha

; Oliveira, Vanessa Fernandes de

; Oliveira, Paula Luanna Carvalho de

; Braga Neto, Pedro

Arquivos de Neuro-Psiquiatria

Journal Metrics
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jan 2022, Volume 80 N. 1 Pages 84 - 96

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Antecedentes: A disfagia é caracterizada como uma dificuldade no padrão de deglutição em qualquer fase desse processo neuromuscular. É um sintoma frequente após o Acidente Vascular Cerebral. Objetivos: O objetivo deste estudo foi investigar as intervenções fonoaudiológicas mais utilizadas como terapia para o tratamento dos distúrbios da deglutição em pacientes com disfagia pós AVC. Métodos: Realizamos uma revisão dos estudos indexados no MEDLINE-PubMed, LILACS, Cochrane e Clinical trials.gov com foco nas intervenções fonoaudiológicas em pacientes adultos e disfágicos após AVC entre janeiro de 2008 e janeiro de 2021. Resultados: Foram selecionados trinta e seis artigos de ensaios clínicos e estudados onze tipos de terapia. Os estudos sobre a eficácia de intervenções terapêuticas para a reabilitação destes pacientes adultos ainda são restritos. A maioria das técnicas é aplicada em combinação com a terapia convencional, tornando inconclusiva a medição da eficácia de outras técnicas isoladamente. Conclusões: As intervenções terapêuticas devem ser escolhidas de acordo com as possibilidades e limitações dos pacientes e, principalmente, com os achados da avaliação clínica e seu objetivo. Antecedentes neuromuscular Cerebral Objetivos Métodos MEDLINEPubMed, MEDLINEPubMed MEDLINE PubMed, PubMed MEDLINE-PubMed LILACS trialsgov trials gov 200 2021 Resultados restritos convencional isoladamente Conclusões principalmente 20 202 2

ABSTRACT Background: Dysphagia is characterized by difficulty in the swallowing pattern at any stage of this neuromuscular process. It is a frequent symptom after stroke. Objective: This study aimed to investigate the most commonly used phonoaudiological interventions as therapy for the treatment of swallowing disorders in patients with dysphagia after stroke. Methods: We performed a review of studies indexed in MEDLINE-PubMed, LILACS, Cochrane, and Clinical trials.gov focusing on speech-language interventions for adult dysphagic patients after stroke between January 2008 and January 2021. Results: Thirty-six articles of clinical trials were selected. Eleven different types of therapies have been studied. Studies on the efficacy of therapeutic interventions for the rehabilitation of adult patients with dysphagia after stroke are still scarce. Most techniques are combined with conventional therapy, so the effectiveness of the other techniques alone cannot be assessed. Conclusions: Therapeutic interventions should be selected in accordance with the possibilities and limitations of the patients, and especially with the findings of the clinical evaluation and with its objective. Background process Objective Methods MEDLINEPubMed, MEDLINEPubMed MEDLINE PubMed, PubMed MEDLINE-PubMed LILACS Cochrane trialsgov gov speechlanguage speech language 200 2021 Results Thirtysix Thirty six studied scarce assessed Conclusions objective 20 202 2

https://doi.org/10.1590/0004-282x-anp-2021-0073

14.

LUMBAR ARTHRODESIS IN DEGENERATIVE SPINE: POST OPERATIVE RESULTS AND RADIOGRAPHIC EVALUATION
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Paula, Fábio Chaud de

; Soares, Ramon Oliveira

; Ribeiro, Gustavo

; Oliveira, Julia Martins de

; Astur Neto, Nelson

; Kanas, MiChel

; Martins, Delio Eulalio

; Roberto, Bruno Braga

; Feres, Felipe

; Gotfryd, Alberto

; Sugino, Rafael Lindi

; Antonioli, Eliane

; Lenza, Mario

; Pohl, Pedro

Coluna/Columna

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2022, Volume 21 N. 3 elocation e262605

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo: Objetivo: Relacionar a taxa de fusão radiográfica e os resultados cirúrgicos nos pacientes submetidos a artrodese posterolateral com instrumentação da coluna lombar para tratamento de afecções degenerativas. Método: Estudo observacional retrospectivo descritivo, tipo série de casos, com base em prontuários médicos e exames de imagem de 76 pacientes maiores de 18 anos (39 a 88 anos), submetidos a artrodese lombar posterolateral. Dados relacionados a presença de comorbidades foram compilados e os desfechos clínicos mensurados por meio de questionários específicos coletados no pré-cirúrgico e após um ano pós-cirúrgico. A qualidade da fusão, conforme descrita por Christensen, foi avaliada a partir de imagens radiográficas por dois examinadores. Os questionários de EVA, EQ-5D e Roland Morris foram utilizados no pré-cirúrgico e um ano pós-cirúrgico para avaliar dor, qualidade de vida e função, respectivamente. Resultado: Observou se melhora na dor, função e qualidade de vida após um ano pós-cirúrgico. A dor, mensurada pelo EVA teve uma redução de 7,92 para 3,16 (p-valor <0,001), a função avaliada pelo escore Roland Morris, também apresentou redução de 14,90 para 7,06 (p-valor <0,001). Culminando com a melhora na qualidade de vida, mensurada pelo EQ-5D, onde observou-se um aumento mediano escore de 0,5672 para 0,7002 (p-valor = 0,002). Conclusão: A ausência de fusão radiográfica não tem correlação direta com piores resultados nos desfechos clínicos em um ano de pós-cirúrgico. Maioritariamente, os pacientes apresentaram melhora clínica sem diferença estatística em relação aos casos em que foi obtido fusão óssea. Nível de evidência IV; Observacional retrospectivo.

ABSTRACT Objective: To relate the radiographic fusion rate and the surgical results in patients undergoing posterolateral arthrodesis with instrumentation of the lumbar spine for the treatment of degenerative disorders. Method: A descriptive, retrospective, case series, observational study, based on medical records and imaging studies of 76 patients over 18 years of age (39 to 88 years) who underwent posterolateral lumbar arthrodesis. Data related to the presence of comorbidities were compiled and clinical outcomes were measured using specific questionnaires collected pre-surgical and 1 year after surgery. Fusion quality, as described by Christensen, was assessed from radiographic images by two examiners. The VAS, EQ-5D and Roland Morris questionnaires were used preoperatively and 1 year after surgery to assess pain, quality of life and function, respectively. Result: It was observed improvement in pain, function and quality of life after 1 year post-surgical. Pain, measured by VAS, had a reduction from 7.92 to 3.16 (p-value <0.001), the function evaluated by the Roland Morris score, also showed a reduction from 14.90 to 7.06 (p-value <0.001) . Culminating with the improvement in quality of life, measured by the EQ-5D, where there was a median increase in the score from 0.5672 to 0.7002 (p-value = 0.002). Conclusion: The absence of radiographic fusion has no direct correlation with worse results in clinical outcomes at 01 year after surgery. Most patients showed clinical improvement with no statistical difference in relation to cases in which bone fusion was obtained. Level of evidence IV; retrospective observation.

Resumen: Objetivo: Relacionar ei índice de fusión radiográfica y los resultados quirúrgicos en pacientes sometidos a artrodesis posterolateral con instrumentación de columna lumbar para el tratamiento de trastornos degenerativos. Método: Estudio descriptivo, retrospectivo, serie de casos, observacional, basado en historias clínicas y estudios de imagen de 76 pacientes may ores de 18 anos (39 a 88 anos) a quienes se les realizó artrodesis lumbar posterolateral. Se recopilaron datos relacionados con la presencia de comorbilidades y se midieron los resultados clínicos mediante cuestionarios específicos recogidos antes de la cirugía y al año de la cirugía. La calidad de la fusión, según lo descrito por Christensen, fue evaluada a partir de imágenes radiográficas por dos examinadores. Los cuestionarios VAS, EQ-5D y Roland Morris se utilizaron en el preoperatorio y 1 año después de la cirugía para evaluar el dolor, la calidad de vida y la función, respectivamente. Resultado: Se observó mejoría en el dolor, función y calidad de vida después de 1 año posquirúrgico. El dolor, medido por EVA, tuvo una reducción de 7,92 a 3,16 (p-valor <0,001), la función evaluada por el puntaje de Roland Morris, también mostró una reducción de 14,90 a 7,06 (p-valor <0,001). Culminando con la mejora en la calidad de vida, medida por el EQ-5D, donde hubo un aumento mediano en el puntaje de 0,5672 a 0,7002 (p-valor = 0,002). Conclusión: La ausencia de fusión radiográfica no tiene correlación directa con peores resultados en los resultados clínicos al 01 año de la cirugía. La mayoría de los pacientes presentaron mejoría clínica sin diferencia estadística en relación a los casos en los que se obtuvo fusión ósea. Nivel de evidencia IV; observación retrospectiva.

https://doi.org/10.1590/s1808-185120222103262605

15.

COVID-19 in the Perioperative Period of Cardiovascular Surgery: the Brazilian Experience
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Gomes, Walter J.

; Rocco, Isadora

; Pimentel, Wallace S.

; Pinheiro, Aislan H. B.

; Souza, Paulo M. S.

; Costa, Luiz A. A.

; Teixeira, Marjory M. P.

; Ohashi, Leonardo P.

; Bublitz, Caroline

; Begot, Isis

; Moreira, Rita Simone L

; Hossne Jr, Nelson A.

; Vargas, Guilherme F.

; Branco, João Nelson R.

; Teles, Carlos A.

; Medeiros, Eduardo A. S.

; Sáfadi, Camila

; Rampinelli, Amândio

; Moratelli Neto, Leopoldo

; Rosado, Anderson Rosa

; Mesacasa, Franciele Kuhn

; Capriata, Ismael Escobar

; Segalote, Rodrigo Coelho

; Palmieri, Deborah Louize da Rocha Vianna

; Jardim, Amanda Cristina Mendes

; Vianna, Diego Sarty

; Coutinho, Joaquim Henrique de Souza Aguiar

; Jazbik, João Carlos

; Coutinho, Henrique Madureira da Rocha

; Kikuta, Gustavo

; Almeida, Zely Sant'Anna Marotti de

; Feguri, Gibran Roder

; Lima, Paulo Ruiz Lucio de

; Franco, Anna Carolina

; Borges, Danilo de Cerqueira

; Cruz, Felipe Ramos Honorato De La

; Croti, Ulisses Alexandre

; Borim, Bruna Cury

; Marchi, Carlos Henrique De

; Goraieb, Lilian

; Postigo, Karolyne Barroca Sanches

; Jucá, Fabiano Gonçalves

; Oliveira, Fátima Rosane de Almeida

; Souza, Rafael Bezerra de

; Zilli, Alexandre Cabral

; Mas, Raul Gaston Sanchez

; Bettiati Junior, Luiz Carlos

; Tranchesi, Ricardo

; Bertini Jr, Ayrton

; Franco, Leandro Vieira

; Fernandes, Priscila

; Oliveira, Fabiana

; Moraes Jr, Roberto

; Araújo, Thiago Cavalcanti Vila Nova de

; Braga, Otávio Penna

; Pedrosa Sobrinho, Antônio Cavalcanti

; Teixeira, Roberta Tavares Barreto

; Camboim, Irla Lavor Lucena

; Gomes, Eduardo Nascimento

; Reis, Pedro Horigushi

; Garcia, Luara Piovan

; Scorsioni, Nelson Henrique Goes

; Lago, Roberto

; Guizilini, Solange

Brazilian Journal of Cardiovascular Surgery

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dec 2021, Volume 36 N. 6 Pages 725 - 735

Abstract: En | Text: En | PDF: En

Abstract Introduction: We investigated the clinical course and outcomes of patients submitted to cardiovascular surgery in Brazil and who had developed symptoms/signs of coronavirus disease 2019 (COVID-19) in the perioperative period. Methods: A retrospective multicenter study including 104 patients who were allocated in three groups according to time of positive real time reverse transcriptase-polymerase chain reaction (RT-PCR) for the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2): group 1, patients who underwent cardiac surgery > 10 days after positive RT-PCR; group 2, patients with a positive RT-PCR within 10 days before or after surgery; group 3, patients who presented positive RT-PCR > 10 days after surgery. The primary outcome was mortality and secondary outcomes were postoperative complications, intensive care unit (ICU) length of stay, and postoperative days of hospitalization. Results: The three groups were similar with respect to age, the European System of Cardiac Operative Risk Evaluation score, and comorbidities, except hypertension. Postoperative complications and death were significantly higher in groups 2 and 3 than in group 1, and no significant difference between groups 2 and 3 was seen. Group 2 showed a high prevalence of surgery performed as an urgent procedure. Although no significant differences were observed in ICU length of stay, total postoperative hospitalization time was significantly higher in group 3 than in groups 1 and 2. Conclusion: COVID-19 affecting the postoperative period of patients who underwent cardiovascular surgery is associated with a higher rate of morbidity and mortality. Delaying procedures in RT-PCR-positive patients may help reduce risks of perioperative complications and death.

https://doi.org/10.21470/1678-9741-2021-0960

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