ABSTRACT Objective: Intrauterine environment can induce fetal metabolic programming that predisposes to adiposity-related chronic diseases in its lifespan. We examined the associations of parental nutritional status and gestational weight gain with offspring body composition in early adulthood. Materials and methods: This is cross-sectional analysis of female participants of the NutriHS who were submitted to questionnaires, clinical examinations and body composition assessed by DXA. Association of pre-conception parental BMI and maternal gestational weight gain (exposures) with body composition measurements (outcomes) were analyzed using multiple linear models adjusted for Directed Acyclic Graphs-based covariables (maternal and paternal educational level, maternal age, and tobacco, alcohol and/or drugs use). The sample included 124 women (median 28 (24-31) years) with a mean BMI of 25.4 ± 4.7 kg/m2. Results: No association between previous paternal BMI and offspring’s body composition was detected. In the fully adjusted linear regression model, maternal BMI was associated with offspring’s total lean mass (β = 0.66, p = 0.001), appendicular skeletal muscle mass index (ASMI) (β = 0.11, p = 0.003) and fat mass index (FMI) (β = 0.03, p = 0.039). Gestational weight gain was associated with increased offspring’s BMI (OR 1.12 [95% CI 1.02-1.20], p = 0.01). The linear regression model adjusted for maternal age and maternal and paternal education levels showed associations of gestational weight gain with offspring’s ASMI (β = 0.42, p = 0.046), FMI (β = 0.22, p = 0.005) and android-to-gynoid fat ratio (β = 0.09, p = 0.035). Conclusion: Our findings suggest that preconception maternal BMI could influence lean mass and general adiposity of young adult female offspring and that gestational weight gain could be useful for predicting centrally distributed adiposity. Objective adiposityrelated related lifespan adulthood methods crosssectional cross sectional questionnaires DXA pre conception exposures (exposures outcomes (outcomes Graphsbased Graphs based level tobacco andor or use. use . use) 12 median 2 2431 24 31 (24-31 years 254 25 4 25. 47 7 4. kgm2 kgm kg m2 m kg/m2 Results offsprings s detected β 066 0 66 0.66 0.001, 0001 0.001 , 001 0.001) (ASMI 011 11 0.11 0.003 0003 003 (FMI 03 0.03 0.039. 0039 0.039 039 0.039) OR 112 1 1.1 95% 95 [95 1.021.20, 102120 1.02 1.20 02 20 1.02-1.20] 0.01. 0.01 01 0.01) 042 42 0.42 0.046, 0046 0.046 046 0.046) 022 22 0.22 0.005 0005 005 androidtogynoid android gynoid 009 09 0.09 0.035. 0035 0.035 035 0.035) Conclusion 243 3 (24-3 kg/m 06 6 0.6 000 0.00 00 0.1 0.0 1. 9 [9 021 1.021.20 10212 102 1.0 120 1.2 1.02-1.20 04 0.4 004 0.04 0.2 (24- 0. [ 1.021.2 1021 10 1.02-1.2 (24 1.021. 1.02-1. (2 1.021 1.02-1 ( 1.02-

ABSTRACT Background: Although performance of rapid immunochromatographic tests (RITs) for dengue virus (DENV) serotypes 1, 2 and 3 is relatively settled, evidence on accuracy of RITs for DENV-4 are based on studies with small sample sizes and with discrepant results. Objectives: To assess accuracy and inter-observer agreement of RITs targeting dengue nonstructural protein-1 (NS1) antigen - Dengue NS1-Bioeasy™, Dengue NS1 Ag Strip-Bio-Rad™, IVB Dengue Ag NS1-Orangelife™ and Dengue NS1-K130-Bioclin™ in DENV-4 samples. Methods: Study sample (n = 324) included adults presenting at an emergency unit in Rio de Janeiro, Brazil, with fever of ≤72 h and two or more dengue symptoms. A serum sample from each patient was tested by each RIT. A positive reverse-transcription polymerase chain reaction was considered as the reference standard for dengue diagnosis. The diagnostic parameters analyzed for each RIT were sensitivity, specificity, positive and negative predictive values, and likelihood ratios. Each RIT was read by homogeneous (two junior nurses) or heterogeneous (one junior nurse and one senior biologist) pairs. Agreement was estimated by simple kappa with 95% confidence interval, positive (Ppos) and negative (Pneg) proportion concordance and prevalence and bias adjusted kappa, rated from poor (k < 0.0) to almost perfect (0.8 < k < 1.0), and perfect (k = 1). Results: NS1 RITs for DENV-4 diagnosis showed high specificity (95.9%-99.4%), but low sensitivity (14.7%-45.4%). Bioeasy™ had the best performance, with a positive likelihood ratio of 26.0 (95% CI: 8.4;81.0). Inter-observer agreement was almost perfect for all evaluated RITs. Mismatches in confirmed dengue were more common for the Bioclin™ (Ppos 88.3-90.0 %) and Orangelife™ (Ppos 91.7-94.1 %) tests. Conclusions: For DENV-4, the tested RITs had high specificity, but lower sensitivity compared to published results for other serotypes. They should not be used for screening purposes. Different brands may have very different performances. This should be considered upon deciding of using RITs in DENV-4 outbreaks.

O objetivo deste artigo é avaliar o estado nutricional dos usuários dos restaurantes e refeitório populares de Belo Horizonte e identificar fatores associados ao excesso de peso. Estudo analítico transversal, conduzido em adultos de ambos os sexos, nos restaurantes e refeitório populares de Belo Horizonte. O excesso de peso, variável dependente, foi diagnosticado por meio do índice de massa corporal (IMC > 25 kg/m2) e correlacionado com as variáveis sociodemográficas e nível de atividade física. Os dados foram obtidos por meio da aferição direta do peso e da altura e de questionário semiestruturado. Participaram do estudo 1334 indivíduos, sendo a maioria do sexo masculino. A prevalência de excesso de peso foi de 42,9% entre os homens e 45,8% entre as mulheres. Os fatores positivamente associados ao excesso de peso foram: maior idade para ambos os sexos, possuir parceiro para as mulheres e menor prática de atividade física e classe socioeconômica mais elevada para os homens. A identificação dos fatores associados ao excesso de peso revela a necessidade da implantação de uma programação sistemática e eficaz de educação alimentar e nutricional para a prevenção e a remediação desse agravo, para que os restaurantes populares cumpram seu objetivo.

The scope of this article is to assess the nutritional status of users of low-budget restaurants and soup kitchens in Belo Horizonte and to identify factors associated with being overweight. It involved a cross-sectional analytical study conducted among adults of both sexes in low-budget restaurants and soup kitchens in Belo Horizonte. Being overweight was the dependent variable and was defined as body mass index (BMI) eŠ 25 kg/m2. This was correlated with socio-demographic variables and the level of physical activity. The data were obtained directly through weight and height measurement and a semi-structured questionnaire. The study involved 1334 individuals, the majority being male. The prevalence of being overweight was 42.9% among the men and 45.8% among the women. The following factors were positively associated with being overweight: being older for both sexes; having a partner for the women; taking less physical exercise and higher socioeconomic level for the men. Detection of factors associated with being overweight reveals that there is a need to implement an effective systematic program of dietary and nutritional education in order to prevent and remedy this condition, so that low-budget restaurants fulfill their objective.

O objetivo deste artigo é avaliar o estado nutricional dos usuários dos restaurantes e refeitório populares de Belo Horizonte e identificar fatores associados ao excesso de peso. Estudo analítico transversal, conduzido em adultos de ambos os sexos, nos restaurantes e refeitório populares de Belo Horizonte. O excesso de peso, variável dependente, foi diagnosticado por meio do índice de massa corporal (IMC > 25 kg/m2) e correlacionado com as variáveis sociodemográficas e nível de atividade física. Os dados foram obtidos por meio da aferição direta do peso e da altura e de questionário semiestruturado. Participaram do estudo 1334 indivíduos, sendo a maioria do sexo masculino. A prevalência de excesso de peso foi de 42,9% entre os homens e 45,8% entre as mulheres. Os fatores positivamente associados ao excesso de peso foram: maior idade para ambos os sexos, possuir parceiro para as mulheres e menor prática de atividade física e classe socioeconômica mais elevada para os homens. A identificação dos fatores associados ao excesso de peso revela a necessidade da implantação de uma programação sistemática e eficaz de educação alimentar e nutricional para a prevenção e a remediação desse agravo, para que os restaurantes populares cumpram seu objetivo.

The scope of this article is to assess the nutritional status of users of low-budget restaurants and soup kitchens in Belo Horizonte and to identify factors associated with being overweight. It involved a cross-sectional analytical study conducted among adults of both sexes in low-budget restaurants and soup kitchens in Belo Horizonte. Being overweight was the dependent variable and was defined as body mass index (BMI) eŠ 25 kg/m2. This was correlated with socio-demographic variables and the level of physical activity. The data were obtained directly through weight and height measurement and a semi-structured questionnaire. The study involved 1334 individuals, the majority being male. The prevalence of being overweight was 42.9% among the men and 45.8% among the women. The following factors were positively associated with being overweight: being older for both sexes; having a partner for the women; taking less physical exercise and higher socioeconomic level for the men. Detection of factors associated with being overweight reveals that there is a need to implement an effective systematic program of dietary and nutritional education in order to prevent and remedy this condition, so that low-budget restaurants fulfill their objective.

O artigo apresenta uma reflexão sobre a experiência de construção coletiva do mapa de risco em um hospital público, no município do Rio de Janeiro, fundamentada nos conceitos de biossegurança, qualidade total e vigilância em saúde do trabalhador. Partiu da etapa de sensibilização dos trabalhadores e gestores do hospital, da identificação dos riscos, da elaboração do mapa, até a discussão sobre as medidas preventivas e a apresentação dos resultados pelos trabalhadores em centro de estudos. A elaboração do mapa de risco serviu como um processo educativo, que possibilitou socializar conceitos da área de saúde do trabalhador, integrar os trabalhadores, sistematizar o processo de trabalho e refletir sobre a forma de organização do trabalho, gerando desdobramentos práticos sob o ponto de vista da intervenção no ambiente de trabalho.

The paper presents a discussion about the experience of building a risk map by workers in a public hospital, in Rio de Janeiro city, resting on concepts of occupational health surveillance, total quality and biosafety. It goes from the first step to persuade the workers and managers, to identify the potential sources of risk in the work environment, the elaboration of the map, until the discussion about the preventive measures and the presentation of the results by the workers at a scientific meeting in the hospital. The elaboration of the risk map acted as a learning opportunity to socialize concepts in the work health area, to integrate workers, to systematize the work process and to discuss work organization, having practical consequences which have furthered changes in the working environment.

O artigo apresenta uma reflexão sobre a experiência de construção coletiva do mapa de risco em um hospital público, no município do Rio de Janeiro, fundamentada nos conceitos de biossegurança, qualidade total e vigilância em saúde do trabalhador. Partiu da etapa de sensibilização dos trabalhadores e gestores do hospital, da identificação dos riscos, da elaboração do mapa, até a discussão sobre as medidas preventivas e a apresentação dos resultados pelos trabalhadores em centro de estudos. A elaboração do mapa de risco serviu como um processo educativo, que possibilitou socializar conceitos da área de saúde do trabalhador, integrar os trabalhadores, sistematizar o processo de trabalho e refletir sobre a forma de organização do trabalho, gerando desdobramentos práticos sob o ponto de vista da intervenção no ambiente de trabalho.

The paper presents a discussion about the experience of building a risk map by workers in a public hospital, in Rio de Janeiro city, resting on concepts of occupational health surveillance, total quality and biosafety. It goes from the first step to persuade the workers and managers, to identify the potential sources of risk in the work environment, the elaboration of the map, until the discussion about the preventive measures and the presentation of the results by the workers at a scientific meeting in the hospital. The elaboration of the risk map acted as a learning opportunity to socialize concepts in the work health area, to integrate workers, to systematize the work process and to discuss work organization, having practical consequences which have furthered changes in the working environment.