Resumo Objetivou-se realizar uma análise espacial da taxa de mortalidade hospitalar (TMH) por síndrome respiratória aguda grave (SRAG) atribuída à COVID-19 em crianças e adolescentes no Brasil no período de 2020 a 2021. Utilizou-se o método de cluster para agrupar as unidades federativas (UFs) com base na TMH. Em 2020, clusters com altas TMHs foram formados por UFs Norte/Nordeste. Em 2021, houve redução na TMH. Os clusters com maiores taxas permaneceram na região N/NE. Diferenças regionais foram observadas nas TMHs. Os achados podem refletir as desigualdades sociais e o acesso à atenção hospitalar, principalmente na faixa etária de menores de 1 ano pela gravidade da doença neste grupo.

Abstract The objective was to perform a spatial analysis of the hospital mortality rate (HMR) due to severe acute respiratory syndrome (SARS) attributed to COVID-19 among children and adolescents in Brazil from 2020 to 2021. A cluster method was used to group federal units (FUs) based on HMR. In 2020, clusters with high HMRs were formed by north/northeast FUs. In 2021, there was a reduction in HMR. Clusters with higher rates remained in the N/NE region. Regional differences were observed in the HMR. The findings may reflect social inequalities and access to hospital care, especially in the under 1-year-old age group due to the severity of the disease in this group.

Abstract The objective was to perform a spatial analysis of the hospital mortality rate (HMR) due to severe acute respiratory syndrome (SARS) attributed to COVID-19 among children and adolescents in Brazil from 2020 to 2021. A cluster method was used to group federal units (FUs) based on HMR. In 2020, clusters with high HMRs were formed by north/northeast FUs. In 2021, there was a reduction in HMR. Clusters with higher rates remained in the N/NE region. Regional differences were observed in the HMR. The findings may reflect social inequalities and access to hospital care, especially in the under 1-year-old age group due to the severity of the disease in this group.

Resumo Objetivou-se realizar uma análise espacial da taxa de mortalidade hospitalar (TMH) por síndrome respiratória aguda grave (SRAG) atribuída à COVID-19 em crianças e adolescentes no Brasil no período de 2020 a 2021. Utilizou-se o método de cluster para agrupar as unidades federativas (UFs) com base na TMH. Em 2020, clusters com altas TMHs foram formados por UFs Norte/Nordeste. Em 2021, houve redução na TMH. Os clusters com maiores taxas permaneceram na região N/NE. Diferenças regionais foram observadas nas TMHs. Os achados podem refletir as desigualdades sociais e o acesso à atenção hospitalar, principalmente na faixa etária de menores de 1 ano pela gravidade da doença neste grupo.

Resumo Objetivou-se realizar uma análise espacial da taxa de mortalidade hospitalar (TMH) por síndrome respiratória aguda grave (SRAG) atribuída à COVID-19 em crianças e adolescentes no Brasil no período de 2020 a 2021. Utilizou-se o método de cluster para agrupar as unidades federativas (UFs) com base na TMH. Em 2020, clusters com altas TMHs foram formados por UFs Norte/Nordeste. Em 2021, houve redução na TMH. Os clusters com maiores taxas permaneceram na região N/NE. Diferenças regionais foram observadas nas TMHs. Os achados podem refletir as desigualdades sociais e o acesso à atenção hospitalar, principalmente na faixa etária de menores de 1 ano pela gravidade da doença neste grupo. Objetivouse Objetivou se TMH (TMH SRAG (SRAG COVID19 COVID 19 COVID-1 202 2021 Utilizouse Utilizou (UFs NorteNordeste Norte Nordeste Norte/Nordeste NNE N NE N/NE grupo COVID1 COVID- 20 2

Abstract The objective was to perform a spatial analysis of the hospital mortality rate (HMR) due to severe acute respiratory syndrome (SARS) attributed to COVID-19 among children and adolescents in Brazil from 2020 to 2021. A cluster method was used to group federal units (FUs) based on HMR. In 2020, clusters with high HMRs were formed by north/northeast FUs. In 2021, there was a reduction in HMR. Clusters with higher rates remained in the N/NE region. Regional differences were observed in the HMR. The findings may reflect social inequalities and access to hospital care, especially in the under 1-year-old age group due to the severity of the disease in this group. HMR (HMR SARS (SARS COVID19 COVID 19 COVID-1 202 2021 FUs (FUs northnortheast north northeast NNE N NE region care 1yearold yearold 1 year old COVID1 COVID- 20 2

Abstract This cross-sectional study evaluated the association between salivary immunoglobulins, plaque index, and gingival index in Brazilian children with and without type 1 diabetes mellitus (DM1). The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist for the reporting of observational studies was followed. The DM1 group had 38 children, and an equal number of volunteers matched by sex and age were recruited as controls. Clinical examination was performed for plaque index and gingival index determination. Non-stimulated whole saliva was collected. Concentrations of IgA, IgG, and IgM were determined by ELISA test. Data were tested by the Kolmogorov-Smirnov, Mann-Whitney, and Spearman tests and a multiple linear regression model (p<0.05) was performed. Gingival index was higher in the Control (DM1: 0.16±0.17; Control: 0.24±0.23, p=0.040). In DM1, there was a correlation between IgA and age (rho=0.371, p=0.024), IgM and IgG (rho=0.459, p=0.007), and IgM and gingival index (rho=0.394, p=0.014). In DM1, multiple linear regression showed that age (p=0.041; β=0.363), gingival index (p=0.041; β=0.398), and plaque index (p=0.008; β=-0.506) were good predictors of IgA levels in saliva. Thus, IgA was the only researched immunoglobulin that was directly associated with plaque and gingival indices in Brazilian children with DM1, but not in control subjects. crosssectional cross sectional immunoglobulins DM1. DM . (DM1) STROBE (STROBE followed 3 controls determination Nonstimulated Non stimulated collected test KolmogorovSmirnov, KolmogorovSmirnov Kolmogorov Smirnov, Smirnov Kolmogorov-Smirnov MannWhitney, MannWhitney Mann Whitney, Whitney Mann-Whitney p<0.05 p005 p 0 05 (p<0.05 (DM1 0.16±0.17 016017 16 17 024023 24 23 0.24±0.23 p=0.040. p0040 p=0.040 040 p=0.040) rho=0.371, rho0371 rho 371 (rho=0.371 p=0.024, p0024 p=0.024 , 024 p=0.024) rho=0.459, rho0459 459 (rho=0.459 p=0.007, p0007 p=0.007 007 p=0.007) rho=0.394, rho0394 394 (rho=0.394 p=0.014. p0014 p=0.014 014 p=0.014) p=0.041 p0041 041 (p=0.041 β=0.363, β0363 β β=0.363 363 β=0.363) β=0.398, β0398 β=0.398 398 β=0.398) p=0.008 p0008 008 (p=0.008 β=0.506 β0506 β= 0.506 506 β=-0.506 Thus subjects p<0.0 p00 (p<0.0 (DM 0.16±0.1 01601 02402 2 0.24±0.2 p004 p=0.04 04 rho=0.371 rho037 37 (rho=0.37 p002 p=0.02 02 rho=0.459 rho045 45 (rho=0.45 p000 p=0.00 00 rho=0.394 rho039 39 (rho=0.39 p001 p=0.01 01 (p=0.04 β036 β=0.36 36 β039 β=0.39 (p=0.00 β=0.50 β050 0506 0.50 50 β=-0.50 p<0. p0 (p<0. 0.16±0. 0160 0240 0.24±0. p=0.0 rho=0.37 rho03 (rho=0.3 rho=0.45 rho04 4 (rho=0.4 rho=0.39 (p=0.0 β03 β=0.3 β=0.5 β05 050 0.5 5 β=-0.5 p<0 (p<0 0.16±0 016 0.24±0 p=0. rho=0.3 rho0 (rho=0. rho=0.4 (p=0. β0 β=0. 0. β=-0. p< (p< 0.16± 0.24± p=0 rho=0. (rho=0 (p=0 β=0 β=-0 (p 0.16 0.24 p= rho=0 (rho= (p= β=- 0.1 0.2 rho= (rho

Abstract Objectives To present the Brazilian Psychiatric Association’s Consensus on the Management of Acute Intoxication. Methods A group of experts selected by the Brazilian Psychiatric Association searched for articles on the MEDLINE (by PubMed) and Cochrane databases, limited to human studies and acute intoxication. Working groups reviewed these materials for appropriateness to the topic and the quality of the work. A survey was conducted using the Delphi method to produce a table of agreed recommendations presented at the end of the systematic review. Three survey rounds were held to reach consensus. Results Support for intoxication should start with Initial Management: Resuscitation/Life Support/Differential Diagnosis. For this, the group proposed the following sequence of assessments: A (airway), B (breathing), C (circulation), D.1 (disability), D.2 (differential diagnosis), D.3 (decontamination), D.4 (drug antidotes), E (enhanced elimination). The group of experts then presented specific interventions for the main drugs of abuse. Conclusions Management of intoxication with drugs of abuse is complex and requires systematic protocols. The group suggests adoption of the A-B-C-D-E technique first, with constant investigation. Then, specific conduct and support until remission of intoxication. The literature is still scarce in evidence on the subject. Therefore, this consensus was necessary. We believe that at present this document can help psychiatric, general, and emergency physicians deal with emergency psychiatric episodes due to acute intoxication. This work could stimulate future studies on the topic. Associations s Intoxication PubMed databases review ResuscitationLife Resuscitation Life SupportDifferential Differential Diagnosis assessments airway, airway , (airway) breathing, breathing (breathing) circulation, circulation (circulation) D1 D 1 D. disability, disability (disability) D2 2 differential diagnosis, diagnosis diagnosis) D3 3 decontamination, decontamination (decontamination) D4 4 drug antidotes, antidotes antidotes) enhanced elimination. elimination . elimination) protocols ABCDE first investigation Then subject Therefore necessary general (airway (breathing (circulation (disability (decontamination

Resumo Objetivo A primeira onda da COVID-19 foi desafiadora para os profissionais de saúde. Este estudo analisou o enfrentamento do estresse em um hospital universitário. Método De forma online, 181 profissionais responderam: Caracterização Sociodemográfica, Avaliação do Risco e Exposição, Burnout Assessment Tool (BAT-23) e Escala de Coping da COVID-19. Resultados A amostra foi composta principalmente por mulheres, caucasianos, casados, médicos, com um emprego. Tiveram alta exposição e risco à infecção mais de 80% da amostra, com 17,1% positivos. Os estressores mais relatados foram: riscos de transmitir a doença, ser hospitalizado e separado de pessoas queridas; 11% apresentaram risco/provável de burnout, com exaustão e prejuízo emocional. Apresentaram estratégias mais adaptativas, como Resolução de Problemas e Busca de Informações, havendo uma correlação negativa entre coping adaptativo e burnout. Ser médico, com coping mal adaptativo, em atendimento psiquiátrico e ter crença religiosa foram preditores de burnout. Conclusão Promover um coping adaptativo poderá melhorar a saúde mental desses trabalhadores. COVID19 COVID 19 COVID-1 universitário online 18 responderam Sociodemográfica Exposição BAT23 BAT 23 (BAT-23 COVID19. 19. mulheres caucasianos casados médicos emprego 80 171 17 1 17,1 positivos doença queridas 11 riscoprovável provável burnout emocional adaptativas Informações médico trabalhadores COVID1 COVID- BAT2 2 (BAT-2 8 17, (BAT- (BAT

Abstract Objective The first wave of COVID-19 was challenging for healthcare workers. This study analyzed the ways of coping with stress at a university hospital. Method A Sociodemographic Characterization, Risk and Exposure Assessment, Burnout Assessment Tool (BAT-23), and COVID-19 Coping Scale were responded online by 181 professionals. Results The sample was composed mainly of women, white, married, physicians, with one job. Over 80% of the sample were at high exposure and risk for infection, with 17.1% having tested positive. The most reported stressors were risks of transmitting the disease, being hospitalized, and being separated from loved ones; 11% presented the risk of/probable burnout, with exhaustion and emotional impairment. They presented adaptive coping strategies, such as problem-solving and information-seeking, with a negative correlation between adaptive coping and burnout. Being a physician with maladaptive coping, in psychiatric care, and having religious beliefs were predictors of burnout. Conclusion Promoting adaptive coping may improve the mental health of these workers. COVID19 COVID 19 COVID-1 workers hospital Characterization BAT23, BAT23 BAT 23 , (BAT-23) 18 professionals women white married physicians job 80 infection 171 17 1 17.1 positive disease hospitalized ones 11 ofprobable probable burnout impairment strategies problemsolving problem solving informationseeking, informationseeking information seeking, seeking information-seeking care COVID1 COVID- BAT2 2 (BAT-23 8 17. (BAT-2 (BAT- (BAT

ABSTRACT. Evaluation of combined ability can eliminate lines that are inefficient and enable the subsequent program steps to be more successful. The objective of this study was to predict the general (gi) and specific (sij) combination ability of popcorn S1 progenies for early selection. A total of 288 topcrosses were performed under a randomized complete block design with two replicates at two sites (Campinas and Capão Bonito, São Paulo State, Brazil). Diallel analyses were performed using mixed models and the maximum likelihood restricted/best unbiased linear prediction method. Evaluated traits included grain yield (GY; kg ha-1), weight of 100 grains (g), and popping expansion (PE; mL g-1). Ear components were also evaluated, including ear length, ear diameter (cm), and the number of grain rows (unit). The S1 progeny 32 presented the highest gi for GY in Campinas, whereas progeny 46 presented the highest gi for GY in Capão Bonito. The S1 progeny, 114 was an important parent for the popcorn breeding program, because it presented high gi for the traits of agronomic interest at both sites. Combination 86×IAC12 exhibited a high sij, and the 86 parent presented the second-highest gi for PE in Campinas, and it should be used for high PE genotypes.

RESUMO OBJETIVOS Descrever a tendência da atividade física (AF) em quatro domínios realizada por gestantes residentes nas capitais brasileiras e no Distrito Federal (DF) e verificar a associação entre fatores sociodemográficos e a prática de atividade física de lazer entre 2007 e 2017. MÉTODOS Estudo de tendência temporal realizado com dados do Sistema de Vigilância de Fatores de Risco para doenças crônicas por inquérito telefônico (Vigitel). Foram estudadas 3.730 gestantes no período, considerando as variáveis sociodemográficas (idade, macrorregião, trabalho, estado civil, escolaridade, cor) e de atividade física nos quatro domínios (lazer, trabalho, deslocamento, doméstico – sim/não). Para as gestantes que realizavam atividade física de lazer, foi questionada a duração, expressa na variável AF ≥ 150 minutos/semana (sim/não). A tendência temporal foi avaliada por regressão linear ponderada pela variância (variação anual média foi expressa em pontos percentuais – p.p.) e a associação de fatores sociodemográficos com a atividade física de lazer por regressão de Poisson, com estimativa da razão de prevalência (RP). RESULTADOS A prevalência de gestantes com 12 anos ou mais de estudo aumentou no período analisado (+1,37 p.p./ano), assim como a prevalência de gestantes com mais de 35 anos (+1,11 p.p./ano) e aquelas que trabalham (+0,75 p.p./ano). A prevalência de atividade física de lazer pelas gestantes aumentou de 29,3%, em 2007, para 37,6%, em 2017 (+1,37 p.p./ano), e de AF ≥ 150min/semana de 2,3% para 20,6% (+2,33 p.p./ano), respectivamente, e houve redução de atividades físicas domésticas de 63,9% para 38,9% (-1,65 p.p./ano). A prevalência da prática de atividade física de lazer foi superior entre as gestantes com mais de 12 anos de estudo (RP = 2,22; IC95% 1,73–2,84), quando comparadas àquelas com menos de 8 anos, e menor entre gestantes pretas/pardas/indígenas, comparadas às brancas/amarelas (RP = 0,87; IC95% 0,78–0,97). A prevalência da AF ≥ 150min/semana aumentou conforme os anos de escolaridade e idade. CONCLUSÕES A prevalência da prática de atividade física de lazer e sua realização por ≥ 150minutos/semana aumentou no período analisado, e ambas se associaram diretamente à maior escolaridade.

ABSTRACT OBJECTIVES To describe the trend of physical activity (PhA) in four domains performed by pregnant women living in Brazilian capitals and the Federal District (FD) and to verify the association between sociodemographic factors and the practice of leisure-time physical activity between 2007 and 2017. METHODS Time trend study carried out with data from the Surveillance System of Risk Factors for chronic diseases by telephone survey (Vigitel). A total of 3,730 pregnant women were interviewed in the period, considering sociodemographic variables (age, macro-region, work, marital status, schooling, skin color) and physical activity in the four domains (leisure-time, work, commuting, domestic – yes/no). For pregnant women who performed leisure-time physical activity, its duration was inquired, expressed in the variable PhA ≥ 150 minutes/week (yes/no). The time trend was evaluated by variance-weighted linear regression (average annual variation was expressed in percentage points – pp) and the association of sociodemographic factors with leisure-time physical activity by Poisson regression, with prevalence ratio (PR) estimation. RESULTS The prevalence of pregnant women with 12 years of schooling or more increased in the analyzed period (+1.37 pp/year), as well as the prevalence of pregnant women with more than 35 years of age (+1.11 pp/year) and those who work (+0.75 pp/year). The prevalence of leisure-time physical activity by pregnant women increased from 29.3% in 2007 to 37.6% in 2017 (+1.37 pp/year), and of PhA ≥ 150min/week from 2.3% to 20.6% (+2.33 pp/year), respectively, and there was a reduction in domestic physical activities from 63.9% to 38.9% (-1.65 pp/year). The prevalence of leisure-time physical activity was higher among pregnant women with more than 12 years of schooling (PR = 2.22; 95%CI: 1.73–2.84) as compared to those with less than 8 years of age, and lower among black/brown/indigenous pregnant women, compared to white/yellow ones (PR = 0.87; 95%CI: 0.78–0.97). The prevalence of PhA ≥ 150min/week increased according to years of schooling and age. CONCLUSIONS The prevalence of leisure-time physical activity and its performance for ≥ 150 minutes/week increased in the analyzed period, and both were directly associated with greater schooling.

RESUMO OBJETIVOS Descrever a tendência da atividade física (AF) em quatro domínios realizada por gestantes residentes nas capitais brasileiras e no Distrito Federal (DF) e verificar a associação entre fatores sociodemográficos e a prática de atividade física de lazer entre 2007 e 2017. MÉTODOS Estudo de tendência temporal realizado com dados do Sistema de Vigilância de Fatores de Risco para doenças crônicas por inquérito telefônico (Vigitel). Foram estudadas 3.730 gestantes no período, considerando as variáveis sociodemográficas (idade, macrorregião, trabalho, estado civil, escolaridade, cor) e de atividade física nos quatro domínios (lazer, trabalho, deslocamento, doméstico – sim/não). Para as gestantes que realizavam atividade física de lazer, foi questionada a duração, expressa na variável AF ≥ 150 minutos/semana (sim/não). A tendência temporal foi avaliada por regressão linear ponderada pela variância (variação anual média foi expressa em pontos percentuais – p.p.) e a associação de fatores sociodemográficos com a atividade física de lazer por regressão de Poisson, com estimativa da razão de prevalência (RP). RESULTADOS A prevalência de gestantes com 12 anos ou mais de estudo aumentou no período analisado (+1,37 p.p./ano), assim como a prevalência de gestantes com mais de 35 anos (+1,11 p.p./ano) e aquelas que trabalham (+0,75 p.p./ano). A prevalência de atividade física de lazer pelas gestantes aumentou de 29,3%, em 2007, para 37,6%, em 2017 (+1,37 p.p./ano), e de AF ≥ 150min/semana de 2,3% para 20,6% (+2,33 p.p./ano), respectivamente, e houve redução de atividades físicas domésticas de 63,9% para 38,9% (-1,65 p.p./ano). A prevalência da prática de atividade física de lazer foi superior entre as gestantes com mais de 12 anos de estudo (RP = 2,22; IC95% 1,73–2,84), quando comparadas àquelas com menos de 8 anos, e menor entre gestantes pretas/pardas/indígenas, comparadas às brancas/amarelas (RP = 0,87; IC95% 0,78–0,97). A prevalência da AF ≥ 150min/semana aumentou conforme os anos de escolaridade e idade. CONCLUSÕES A prevalência da prática de atividade física de lazer e sua realização por ≥ 150minutos/semana aumentou no período analisado, e ambas se associaram diretamente à maior escolaridade.

ABSTRACT OBJECTIVES To describe the trend of physical activity (PhA) in four domains performed by pregnant women living in Brazilian capitals and the Federal District (FD) and to verify the association between sociodemographic factors and the practice of leisure-time physical activity between 2007 and 2017. METHODS Time trend study carried out with data from the Surveillance System of Risk Factors for chronic diseases by telephone survey (Vigitel). A total of 3,730 pregnant women were interviewed in the period, considering sociodemographic variables (age, macro-region, work, marital status, schooling, skin color) and physical activity in the four domains (leisure-time, work, commuting, domestic – yes/no). For pregnant women who performed leisure-time physical activity, its duration was inquired, expressed in the variable PhA ≥ 150 minutes/week (yes/no). The time trend was evaluated by variance-weighted linear regression (average annual variation was expressed in percentage points – pp) and the association of sociodemographic factors with leisure-time physical activity by Poisson regression, with prevalence ratio (PR) estimation. RESULTS The prevalence of pregnant women with 12 years of schooling or more increased in the analyzed period (+1.37 pp/year), as well as the prevalence of pregnant women with more than 35 years of age (+1.11 pp/year) and those who work (+0.75 pp/year). The prevalence of leisure-time physical activity by pregnant women increased from 29.3% in 2007 to 37.6% in 2017 (+1.37 pp/year), and of PhA ≥ 150min/week from 2.3% to 20.6% (+2.33 pp/year), respectively, and there was a reduction in domestic physical activities from 63.9% to 38.9% (-1.65 pp/year). The prevalence of leisure-time physical activity was higher among pregnant women with more than 12 years of schooling (PR = 2.22; 95%CI: 1.73–2.84) as compared to those with less than 8 years of age, and lower among black/brown/indigenous pregnant women, compared to white/yellow ones (PR = 0.87; 95%CI: 0.78–0.97). The prevalence of PhA ≥ 150min/week increased according to years of schooling and age. CONCLUSIONS The prevalence of leisure-time physical activity and its performance for ≥ 150 minutes/week increased in the analyzed period, and both were directly associated with greater schooling.

RESUMO Objetivos: analisar a percepção dos profissionais de saúde sobre aleitamento materno exclusivo em unidades de Estratégia Saúde da Família do município de Macaé. Métodos: estudo qualitativo realizado em quatro unidades de Estratégia Saúde da Família no município de Macaé, estado do Rio de Janeiro. Entrevistaram-se 30 profissionais de saúde entre março e maio de 2019. Os conteúdos textuais foram processados no software IRaMuTeQ® pela Classificação Hierárquica Descendente. Resultados: os profissionais utilizam diferentes estratégias para ações de promoção, proteção e apoio ao aleitamento materno nas consultas de pré-natal, mas determinantes sociais e culturais são questões importantes que interferem nesse processo, sendo essencial o envolvimento da família para o sucesso dessa prática. Considerações Finais: os profissionais de saúde, incluindo os enfermeiros, necessitam de treinamento e capacitação para fortalecer o apoio e a rede social da gestante e inserir a família nas diferentes estratégias utilizadas para melhorar a adesão ao aleitamento materno exclusivo.

ABSTRACT Objectives: to analyze the perception of health professionals about exclusive breastfeeding in Family Health Strategy units in the city of Macaé. Methods: qualitative study carried out in four units of the Family Health Strategy in the city of Macaé, Rio de Janeiro. Thirty health professionals were interviewed from March to May 2019. Textual contents were processed in the IRaMuTeQ® software by the Descending Hierarchical Classification. Results: professionals use different strategies for actions to promote, protect and support breastfeeding in prenatal consultations, but social and cultural determinants are important issues that interfere in this process, the involvement of the family being essential for the success of this practice. Final Considerations: health professionals, including nurses, need training and qualification to strengthen the support and social network of pregnant women and insert the family in the different strategies used to improve adherence to exclusive breastfeeding.

RESUMEN Objetivos: analizar la percepción de los profesionales de la salud sobre la lactancia materna exclusiva en las unidades de la Estrategia Salud de la Familia de la ciudad de Macaé. Métodos: estudio cualitativo realizado en cuatro unidades de la Estrategia Salud de la Familia en la ciudad de Macaé, Rio de Janeiro. Treinta profesionales de la salud fueron entrevistados de marzo a mayo de 2019. Los contenidos textuales fueron procesados en el software IRaMuTeQ® por la Clasificación Jerárquica Descendente. Resultados: los profesionales utilizan diferentes estrategias de acciones para promover, proteger y apoyar la lactancia materna en las consultas prenatales, pero los determinantes sociales y culturales son cuestiones importantes que interfieren en este proceso, siendo el involucramiento de la familia fundamental para el éxito de esta práctica. Consideraciones Finales: los profesionales de la salud, incluidos los enfermeros, necesitan capacitación y capacitación para fortalecer el apoyo y la red social de la gestante e insertar a la familia en las diferentes estrategias utilizadas para mejorar la adherencia a la lactancia materna exclusiva.

ABSTRACT We described a MRSA bloodstream infection outbreak that was rapidly identified and controlled in a Neonatal Intensive Care Unit after implementation of a bundle of measures, including PCR-screening and HCW decolonization. We found 35% of healthcare workers(HCW) colonized with S. aureus by PCR, one of them that presented skin lesion positive for MSSA (same clone and spa type than two patients). Our findings raise the hypothesis that the outbreak could be related to HCW colonization.

Resumo A leishmaniose visceral (LV) é uma zoonose negligenciada e endêmica presente em todas as regiões do Brasil, mas mesmo assim poucos estudos têm objetivado a detecção inicial da doença. O município de Ourinhos - SP é uma área não receptiva, silenciosa e vulnerável à LV, não havendo até o momento estudos que tenham investigado a soroprevalência no município. Nesse sentido, o presente estudo objetivou determinar a soroprevalência da LV canina em Ourinhos-SP, bem como associar a presença de fatores de risco. Amostras sanguíneas de 604 cães foram obtidas juntamente com a aplicação de questionário socioeconômico, características ambientais e dos animais e conhecimento sobre a doença. As amostras foram submetidas à sorologia por ELISA e novas amostras coletadas de cães reagentes ou suspeitos foram analisadas por método parasitológico direto, hemograma e PCR. Nenhum animal foi considerado positivo na combinação de testes direto e indireto, e as respostas dos tutores indicaram pouco conhecimento sobre a leishmaniose, sendo muitas vezes confundida com outras doenças transmitidas por artrópodes. Dessa forma, de acordo com os métodos propostos, a presença de leishmaniose canina, na cidade de Ourinhos, não foi confirmada. Por isso campanhas de educação em saúde sobre a doença deveriam ser realizadas.

Abstract Visceral leishmaniasis (VL) is a neglected and endemic zoonosis that occurs throughout Brazil; nevertheless, few studies have focused on the early detection of the disease. The municipality of Ourinhos is a non-receptive, silent and vulnerable area for VL, where the seroprevalence of this disease has so far not been investigated. The present study aimed to determine the seroprevalence of canine VL in Ourinhos-SP, and to identify the presence of risk factors. Blood samples were obtained from 604 dogs during a rabies vaccination campaign together with application of a socioeconomic questionnaire, environmental and animal characteristics and tutor's knowledge about the disease. The samples were subjected to indirect ELISA and new samples were collected from reactive and suspect animals, including whole blood and lymph node aspiration evaluated by parasitological method, complete blood count and PCR. No animal was diagnosed as positive based on the combination of direct and indirect tests and the tutors' answers indicated little knowledge about leishmaniasis, being often confused with other diseases transmitted by arthropods; hence, according to the proposed methods, the presence of canine leishmaniasis in the city of Ourinhos was not confirmed and health education campaigns about the disease should be carried out.