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1.
Lipopolysaccharide effects on activation and apoptosis of primordial ovarian follicles in heifers
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Maffi, A.S.
; Rincón, J.A. Alvarado.
; Barbosa, A.A.
; Weiller, M.A.
; Mondadori, R.G.
; Gasperin, B.G.
; Rovani, M.T.
; Cruz, L.A.X.
; Freitas, K.C.
; Schneider, A.
; Corrêa, M.N.
; Feijó, J.O.
; Pino, F.A.B. Del
; Rabassa, V.R.
; Marins, L.
; Brauner, C.C.
.
Arquivo Brasileiro de Medicina Veterinária e Zootecnia
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RESUMO O objetivo do presente estudo foi avaliar o efeito da administração de lipopolissacarídeo (LPS) na ativação e a apoptose de folículos primordiais. Dez novilhas saudáveis (Bos taurus taurus), com idade média de 14 meses, alojadas em sistema de confinamento e alimentadas com TMR, foram utilizadas neste experimento. Os animais foram distribuídos aleatoriamente em dois grupos: grupo LPS (LPS; n = 5), que recebeu duas injeções intravenosas de 0,5μg/kg de peso corporal de lipopolissacarídeo (Sigma Aldrich®) diluído em 2mL de solução salina (0,9% de NaCl), com intervalo de 24h; e grupo controle (CTR; n = 5), que recebeu duas injeções intravenosas de 2mL de solução salina (0,9% de NaCl), com intervalo de 24h. A primeira injeção de LPS foi realizada no d 1, e no d 5 os animais foram abatidos, os ovários foram pesados e as amostras dos ovários foram coletadas para avaliação histológica e molecular. Não houve diferença no número total de folículos, bem como nos diferentes tipos de folículos. Além disso, o desafio com LPS não modulou a expressão de genes relacionados à reserva ovariana (HAM), à sobrevivência oocitária (Survivin), à taxa de ativação (Pten, KIT, KITL1, KITL2, AKT1, SIRT1) e às anormalidades foliculares. Portanto, a exposição ao LPS com intervalo de 24h não teve efeito sobre a taxa de ativação e as anormalidades dos folículos primordiais, bem como não teve efeito sobre a expressão de genes antiapoptóticos e de genes relacionados com a reserva ovariana, a sobrevivência oocitária, a taxa de ativação e as anormalidades dos folículos primordiais. (LPS primordiais Bos taurus, , taurus) 1 meses TMR experimento grupos 5, 5) 05μgkg μgkg 0 5μg kg μg Sigma Aldrich® Aldrich mL 0,9% 09 9 (0,9 NaCl, NaCl NaCl) h CTR (CTR abatidos molecular disso HAM, HAM (HAM) Survivin, Survivin (Survivin) Pten, Pten (Pten KIT KITL1 KITL KITL2 AKT1 AKT SIRT1 SIRT foliculares Portanto 0,9 (0, (HAM (Survivin 0, (0 (
ABSTRACT The objective of the present study was to evaluate the effect of lipopolysaccharide (LPS) administration on activation and apoptosis of primordial follicles. There was no difference in the total number of follicles as well as in the different types of follicles. Furthermore, the LPS challenge didn’t modulate the expression of genes related with ovarian reserve (HAM), oocyte survival (Survivin), activation rate (Pten, KIT, KITL1, KITL2, AKT1, SIRT1), and follicular abnormalities. Therefore, the LPS exposure with 24h interval had no effect on activation rate and primordial follicles abnormalities, and also had no effect on expression of anti-apoptotic genes and genes related with ovarian reserve, oocyte survival, activation rate, and primordial follicles abnormalities. (LPS Furthermore didnt didn t HAM, HAM , (HAM) Survivin, Survivin (Survivin) Pten, Pten (Pten KIT KITL1 KITL KITL2 AKT1 AKT SIRT1, SIRT1 SIRT SIRT1) abnormalities Therefore h antiapoptotic anti apoptotic (HAM (Survivin
2.
Reproductive traits in different Nile tilapia genetic groups
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Silva, A.C.F.
; Corrêa Filho, R.A.C.
; Ventura, A.S.
; Nunes, A.L.
; Laice, L.M.
; Ribeiro, R.P.
; Oliveira, C.A.L.
; Almeida, L.C.
; Barbosa, P.T.L.
; Povh, J.A.
.
Arquivo Brasileiro de Medicina Veterinária e Zootecnia
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RESUMO O objetivo deste estudo foi avaliar as características reprodutivas dos grupos genéticos AquaAmérica não endogâmicos e endogâmicos, GIFT e AquaAmérica × GIFT. Foram utilizados seis peixes de cada grupo genético (duas fêmeas:um macho). As fêmeas foram examinadas quanto à presença de ovos na boca a cada quatro dias, durante 12 semanas. A reprodução ocorreu em todos os grupos genéticos (GIFT: 100%; AquaAmérica não endogâmica e AquaAmérica × GIFT: 75%; AquaAmérica endogâmica: 50%). Peso e comprimento padrão de fêmea, peso total de desova, fecundidade absoluta, fecundidade relativa, índice de desova e taxa de eclosão não diferiram significativamente entre os grupos genéticos. Entretanto, a variedade não endogâmica da AquaAmérica apresentou valores mais baixos (P<0,05) para diâmetro do ovo (2,4mm) e peso do ovo (4,2mg) e maiores valores (P<0,05) para número relativo de ovos (247,6 ovos/g de ovo ) que GIFT (diâmetro do ovo: 2,8mm; peso do ovo: 5,7mg; número relativo de ovos: 175,4 ovos/g de ovo) e AquaAmérica × GIFT (diâmetro do ovo: 2,8mm; peso do ovo: 5,9mg; número relativo de ovos: 168,8 ovos/g de ovo). Em conclusão, a variedade AquaAmérica não endogâmica produz ovos menores e mais leves, mas um número relativo maior de ovos que a variedade GIFT e o cruzamento AquaAmérica × GIFT; a consanguinidade afeta negativamente a taxa de desova.
ABSTRACT The aim of this study was to evaluate the reproductive traits of the non-inbred and inbred AquaAmérica, GIFT and AquaAmérica × GIFTgenetic groups. Six fish from each genetic group were used (2 females:1 male). Females were examined for the presence of eggs in their mouth at every four days, for 12 weeks. Reproduction occurred in all genetic groups (GIFT: 100%; non-inbred AquaAmérica and AquaAmérica ×GIFT: 75%; inbred AquaAmérica: 50%). Female weight, female standard length, total spawning weight, absolute fecundity, relative fecundity, spawn index and hatching rate did not differ significantly between the genetic groups. However, the non-inbred AquaAmérica variety showed lower values (P<0.05) for egg diameter (2.4mm) and egg weight (4.2mg) and higher values (P<0.05) for relative number of eggs (247.6 eggs/g of egg) than GIFT (egg diameter: 2.8mm; egg weight: 5.7mg; relative number of eggs: 175.4 eggs/g of egg) and AquaAmérica ×GIFT (egg diameter: 2.8mm; egg weight: 5.9mg; relative number of eggs: 168.8 eggs/g of egg). In conclusion, the non-inbred AquaAmérica variety produces smaller, lighter eggs but a higher relative number of eggs than the GIFT variety and the AquaAmérica ×GIFT cross; and inbreeding negatively affects spawning rate.
https://doi.org/10.1590/1678-4162-11764
633 downloads
3.
Sequential Application of Herbicides Alone and in Mixture With and Without Foliar Fertilizer after Pruning of Cassava Plants
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RESUMO: Após a poda da mandioca, inicia-se um novo ciclo de crescimento, sendo necessário o controle das plantas daninhas. Portanto, objetivou-se neste estudo avaliar a seletividade e a eficiência da aplicação sequencial de herbicidas isolados e em misturas em tanque com e sem adição de adubo foliar, depois da poda da mandioca. Realizaram-se dois experimentos com delineamento experimental de blocos casualizados com quatro repetições. Os tratamentos do experimento 1 consistiram em: testemunha sem capina, testemunha capinada, mesotriona, mesotriona/mesotriona, [mesotriona+adubo foliar]/[mesotriona+adubo foliar], mesotriona/[mesotriona+adubo foliar], [mesotriona+cletodim], [mesotriona+cletodim+adubo foliar]/[mesotriona+ cletodim+adubo foliar], [mesotriona+cletodim]/[mesotriona+cletodim], [mesotriona+cletodim]/clorimuron, [mesotriona+ cletodim]/clorimuron+adubo foliar], [mesotriona+cletodim+adubo foliar]/[clorimuron+ cletodim+adubo foliar], [mesotriona+cletodim]/[clorimuron+cletodim]. Os tratamentos do experimento 2 consistiram em: testemunha sem capina, testemunha capinada, clorimuron, [clorimuron+adubo foliar]/[clorimuron+adubo foliar], clorimuron/clorimuron, clorimuron+cletodim, [clorimuron+cletodim+adubo foliar]/[clorimuron+cletodim+adubo foliar], [clorimuron+cletodim] /[clorimuron+cletodim], [clorimuron+cletodim]/[mesotriona+adubo foliar], [clorimuron+cletodim]/mesotriona, [clorimuron+cletodim+adubo foliar]/[mesotriona+cletodim+adubo foliar], [clorimuron+cletodim]/[mesotriona+cletodim]. As doses utilizadas em ambos os experimentos de mesotriona, cletodim e clorimuron foram de 240, 120 e 20 g ha-1, respectivamente, enquanto para o adubo foliar utilizaram-se 2,5 L do produto comercial (Amino Plus®). A primeira aplicação ocorreu 50 dias após a poda, e a segunda, aos 22 dias após a primeira aplicação. No experimento 1, a aplicação do mesotriona, mesotriona/mesotriona e [mesotriona+cletodim]/[mesotriona+cletodim] apresentaram seletividade à mandioca e foram eficientes no controle de plantas daninhas. No experimento 2, o clorimuron+cletodim]/mesotriona, [clorimuron+cletodim+adubo foliar] /[mesotriona+cletodim+ adubo foliar] e [clorimuron+cletodim]/[mesotriona+cletodim] foram eficientes no controle, porém todos os tratamentos não foram seletivos. A adição de adubo foliar à calda não contribuiu para o aumento da seletividade.
ABSTRACT: A new cycle of growth begins after pruning of cassava, and weed control is necessary. Thus, this study aimed to evaluate the selectivity and efficiency of sequential application of herbicides alone and in mixture with and without of foliar fertilizer after pruning of cassava. Two experiments were carried out in a randomized block design with four replications. The treatments of Experiment 1 consisted of control without weeding; control with weeding; mesotrione; mesotrione/mesotrione; mesotrione + foliar fertilizer/mesotrione + foliar fertilizer; mesotrione/mesotrione + foliar fertilizer; mesotrione + clethodim; mesotrione + clethodim + foliar fertilizer/mesotrione + clethodim + foliar fertilizer; mesotrione + clethodim/mesotrione + clethodim; mesotrione + clethodim/chlorimuron; mesotrione + clethodim/chlorimuron + foliar fertilizer; mesotrione + clethodim + foliar fertilizer/chlorimuron + clethodim + foliar fertilizer; mesotrione + clethodim/chlorimuron + clethodim]. Treatments of Experiment 2 consisted of control without weeding; control with weeding; chlorimuron; chlorimuron + foliar fertilizer/chlorimuron + foliar fertilizer; chlorimuron/chlorimuron; chlorimuron + clethodim; chlorimuron + clethodim + foliar fertilizer/chlorimuron + clethodim + foliar fertilizer; chlorimuron + clethodim/chlorimuron + clethodim; chlorimuron + clethodim/mesotrione + foliar fertilizer; chlorimuron + clethodim/mesotrione; chlorimuron + clethodim + foliar fertilizer/mesotrione + clethodim + foliar fertilizer; chlorimuron + clethodim/mesotrione + clethodim. The doses of mesotrione, clethodim, and chlorimuron used in both experiments were 240, 120, and 20 g ha-1, respectively, while 2.5 L of the commercial product Amino Plus® was used as foliar fertilizer. The first application was carried out at 50 days after pruning and the second application at 22 days after the first application. In Experiment 1, the application of mesotrione, mesotrione/mesotrione, and mesotrione + clethodim/mesotrione + clethodim showed selectivity to cassava and were efficient in weed control. In Experiment 2, chlorimuron + clethodim/mesotrione, chlorimuron + clethodim + foliar fertilizer/mesotrione + clethodim + foliar fertilizer, and chlorimuron + clethodim/mesotrione + clethodim were efficient in weed control, but no treatment was selective. The addition of foliar fertilizer to the spray solution did not contribute to increase selectivity.
https://doi.org/10.1590/s0100-83582020380100004
1548 downloads
4.
Addition of chlorogenic acid and caffeine during the processing of cooled boar semen
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Pereira, B.A.
; Rocha, L.G.P.
; Teles, M.C.
; Silva, W.E.
; Barbosa, J.A.
; Rabelo, S.S.
; Uchoa, A.S.
; Rodrıguez-Gil, J. E.
; Pereira, L.J.
; Zangeronimo, M.G.
.
Arquivo Brasileiro de Medicina Veterinária e Zootecnia
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RESUMO O objetivo deste estudo foi avaliar os efeitos da adição de ácido clorogênico (ChA) antes do resfriamento e sua combinação com cafeína adicionada durante o reaquecimento sobre a qualidade do sêmen suíno resfriado. Dez ejaculados foram diluídos em diluidor comercial com adição ou não de 4,5mg/mL de ChA e armazenados a 15°C. Após zero, 24 e 72 horas de armazenamento, 10mL foram retirados e incubados a 37°C na presença ou ausência de 8,0mM de cafeína. A qualidade seminal foi avaliada após 10 e 120 minutos de incubação. O ChA aumentou (P<0,01) a motilidade, a viabilidade, a integridade acrosomal e a porcentagem de espermatozoides com alta atividade mitocondrial (PMHA), entretanto diminuiu (P<0,01) a concentração de malondialdeído (MDA). A cafeína aumentou (P<0,05) a motilidade, a viabilidade, a PMHA e a concentração de MDA e reduziu a integridade acrossomal. Quando associados (ChA+cafeína), houve aumento (P<0,05) na motilidade, na PMHA, na viabilidade e na integridade acrossomal. Conclui-se que a adição de ChA ao meio de diluição melhora a qualidade das doses inseminantes de suínos. A adição de cafeína durante o reaquecimento só é recomendada ao sêmen adicionado de ChA quando esse for armazenado por períodos prolongados (72h), devendo a dose inseminante ser utilizada imediatamente após sua adição.
ABSTRACT A study was conducted to evaluate the effect of chlorogenic acid (ChA) added pre-cooling and its combination with caffeine added during warming on cooled-stored boar semen parameters. Ten ejaculates were diluted in commercial extender with or without 4.5mg/ml ChA and stored at 15°C. After 0, 24 and 72 hours of storage, aliquots of these doses were taken and incubated at 37°C in the presence or absence of 8.0mM caffeine. Semen quality was evaluated after 10 and 120 minutes of incubation. The ChA increased (P <0.01) the sperm motility, viability, acrosomal integrity and the percentage of spermatozoa with high mitochondrial activity (PMHA), however, decreased (P <0.01) the malondialdehyde (MDA) concentration. Caffeine increased (P<0.05) the sperm motility, viability, PMHA and the MDA concentration and reduced (P <0.05) the acrosome integrity. When associated (ChA+caffeine), there was an increase (P <0.05) in sperm motility and viability, PMHA and acrosome integrity. The addition of ChA to the dilution medium improves the quality of the swine inseminating doses. The addition of caffeine during re-warming is only recommended when the semen is stored for prolonged periods (72h), and the inseminating dose should be used immediately after its addition.
https://doi.org/10.1590/1678-4162-10415
983 downloads
5.
Biological Cycle of Susceptible and Glyphosate-Resistant Sourgrass Biotypes in Two Growth Periods
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RESUMO: A seleção de Digitaria insularis resistente ao glyphosate pode causar alteração no ciclo biológico da espécie. Portanto, objetivou-se neste estudo avaliar o ciclo biológico de biótipos de D. insularis suscetível e resistentes ao glyphosate em dois períodos de crescimento (verão/outono e outono/inverno). As sementes foram coletadas nos municípios de Alagoa Grande (07o02’59" S 35o37’01,5" W), considerado suscetível (S1), Cascavel (24o55’27" S 53o27’54,6" W), resistente 1 (R1), Entre Rios do Oeste (24o40’44" S 54o17’05" W), resistente 2 (R2), e Marechal Cândido Rondon (24o42’30" S 54o21’10" W), resistente 3 (R3). As avaliações foram realizadas no período de verão/outono e outono/inverno. As épocas de coleta das plantas foram: 14, 21, 28, 35, 42, 49, 56, 63, 70, 77, 84, 91, 98, 105, 112 e 119 dias após a emergência (DAE). A seleção de biótipos de D. insularis resistentes ao glyphosate em áreas agrícolas afetou a biologia da espécie, em relação à população original de biótipo suscetível. No período do verão/outono (temperatura média de 24,6 oC), o biótipo S iniciou a emissão de perfilhos e o florescimento, em média, aos 14 e 21 DAE, respectivamente, antes que os biótipos resistentes. Entretanto, no período outono/inverno (temperatura média de 19,0 oC), apenas o biótipo R1 conseguiu se desenvolver e finalizar o ciclo biológico. Os biótipos avaliados apresentaram diferenças durante o desenvolvimento principalmente entre as fases fenológicas, de modo que o biótipo suscetível foi o mais precoce e com elevado potencial reprodutivo. As avaliações fisiológicas não apresentaram diferenças entre os biótipos S, R1, R2 e R3, conforme verificado na TCR.
ABSTRACT: Selecting glyphosate-resistant Digitaria insularis may cause changes in the biological cycle of the species. Therefore, the objective of this study was to evaluate the biological cycle of susceptible and glyphosate-resistant D. insularis biotypes in two growth periods (summer/autumn and autumn/winter). Seeds were collected in the municipality of Alagoa Grande (07o02’59" S 35o37’01,5" W), and were considered susceptible (S1), in Cascavel (24o55’27" S 53o27’54.6 ”W) considered as resistant 1 (R1), Entre Rios do Oeste (24o40’44" S 54o17’05" W) considered as resistant 2 (R2) and Marechal Cândido Rondon (24o42’30" S 54o21’10" W) considered as resistant 3 (R3). Evaluations were carried out in the summer/autumn and autumn/winter periods. The collection periods of plants were: 14; 21; 28; 35; 42; 49; 56; 63; 70; 77; 84; 91; 98; 105; 112 and 119 days after emergence (DAE). The selection of glyphosate-resistant D. insularis biotypes in agricultural areas affected the biology of the species, in relation to the original population of the susceptible biotype. In the summer/autumn period (mean temperature 24.6 oC), the S biotype started the emission of tillers and flowering at 14 and 21 DAE on an average, respectively, before the resistant biotypes. However, in the autumn/winter period (mean temperature 19.0 oC) only the R1 biotype was able to develop and complete the biological cycle. The evaluated biotypes presented differences during the development, mainly between the phenological stages, so that the susceptible biotype was the most precocious and with a high reproductive potential. The physiological evaluations showed no differences among the S, R1, R2 and R3 biotypes, as verified in the TCR.
https://doi.org/10.1590/s0100-83582018360100077
746 downloads
6.
Características produtivas, carcaça, cortes e resposta imune humoral de frangos de corte alimentados com diferentes fontes de óleo e vitamina E
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Barbosa Filho, J.A.
; Soares, A.L.
; Santos, M.C.
; Venancio, E.J.
; Almeida, M.
; Bueno, F.R.
; Shimokomaki, M.
; Oba, A.
.
Arquivo Brasileiro de Medicina Veterinária e Zootecnia
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RESUMO A adição de óleos na dieta de frangos de corte proporciona muitas vantagens, visto que, dependendo do perfil de ácidos graxos, pode melhorar o desempenho e atuar como estimulante do sistema imune. Assim, este estudo teve como objetivo avaliar as características produtivas, o rendimento de carcaça, os cortes e a resposta imune humoral de frangos de corte alimentados com diferentes fontes de óleos e vitamina E. Foram utilizados 312 pintainhos de corte machos da linhagem Cobb com um dia de idade, distribuídos em delineamento inteiramente ao acaso, com oito repetições compostas de 13 aves por parcela experimental. Os tratamentos experimentais consistiram em óleo de soja, óleo de canola e óleo de canola mais adição de vitamina E. As variáveis analisadas foram ganho de peso, consumo de ração, conversão alimentar, rendimento de carcaça, cortes comerciais e resposta imune humoral. Os resultados obtidos mostram que houve diferença significativa no desempenho somente na fase pré-inicial, quando as aves que receberam o tratamento com óleo de canola e vitamina E apresentaram piores ganhos de peso. Não foram observadas diferenças significativas para as outras variáveis analisadas. Conclui-se que a utilização de diferentes fontes lipídicas associadas ou não à vitamina E não afeta as características produtivas de carcaça, cortes e resposta imune humoral em frangos de corte em relação ao uso de óleo de soja.
ABSTRACT Oil inclusion in poultry diets provides many advantages and according to the fatty acid profile it is possible to achieve performance improvement as well as immune system stimulation. Thus, the study aimed to evaluate productive performance, carcass and cuts yields and also the humoral immune response of broilers consuming diets formulated with different oil sources and vitamin E. A total of 312 one-day old male Cobb was distributed, in a completely randomized design, in three treatments with eight replications of 13 birds. The experimental treatments were the diets that had different oil source as follows: soybean oil, canola oil and canola oils with vitamin E. The analyzed parameters were weight gain, feed intake, feed conversion ratio, carcass and cut yields and humoral immune response. For the treatment with canola oil and vitamin E a reduction on weight gain during the pre-starter stage was observed. For the other evaluated parameters, no significant differences were observed. In conclusion, the use of canola oil or canola oil with added vitamin E does not affect the productive performance, carcass and cut yields and humoral immune response in broiler chicken in relation soybean oil use.
https://doi.org/10.1590/1678-4162-8975
1459 downloads
7.
Hepatic Osteodystrophy: The Mechanism of Bone Loss in Hepatocellular Disease and the Effects of Pamidronate Treatment
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Spirlandeli, Adriano L.
; Dick-de-Paula, Ingrid
; Zamarioli, Ariane
; Jorgetti, Vanda
; Ramalho, Leandra N.Z.
; Nogueira-Barbosa, Marcello H.
; Volpon, Jose B.
; Jordão, Alceu A.
; Cunha, Fernando Q.
; Fukada, Sandra Y.
; de Paula, Francisco J.A.
.
OBJECTIVES: The present study was designed to evaluate the bone phenotypes and mechanisms involved in bone disorders associated with hepatic osteodystrophy. Hepatocellular disease was induced by carbon tetrachloride (CCl4). In addition, the effects of disodium pamidronate on bone tissue were evaluated. METHODS: The study included 4 groups of 15 mice: a) C = mice subjected to vehicle injections; b) C+P = mice subjected to vehicle and pamidronate injections; c) CCl4+V = mice subjected to CCl4 and vehicle injections; and d) CCl4+P = mice subjected to CCl4 and pamidronate injections. CCl4 or vehicle was administered for 8 weeks, while pamidronate or vehicle was injected at the end of the fourth week. Bone histomorphometry and biomechanical analysis were performed in tibiae, while femora were used for micro-computed tomography and gene expression. RESULTS: CCl4 mice exhibited decreased bone volume/trabecular volume and trabecular numbers, as well as increased trabecular separation, as determined by bone histomorphometry and micro-computed tomography, but these changes were not detected in the group treated with pamidronate. CCl4 mice showed increased numbers of osteoclasts and resorption surface. High serum levels of receptor activator of nuclear factor-κB ligand and the increased expression of tartrate-resistant acid phosphatase in the bones of CCl4 mice supported the enhancement of bone resorption in these mice. CONCLUSION: Taken together, these results suggest that bone resorption is the main mechanism of bone loss in chronic hepatocellular disease in mice.
https://doi.org/10.6061/clinics/2017(04)07
1147 downloads
8.
Primary Hyperparathyroidism: The Influence of Bone Marrow Adipose Tissue on Bone Loss and of Osteocalcin on Insulin Resistance
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Mendonça, Maira L.
; Batista, Sérgio L.
; Nogueira-Barbosa, Marcello H.
; Salmon, Carlos E.G.
; Paula, Francisco J.A. de
.
OBJECTIVES: Bone marrow adipose tissue has been associated with low bone mineral density. However, no data exist regarding marrow adipose tissue in primary hyperparathyroidism, a disorder associated with bone loss in conditions of high bone turnover. The objective of the present study was to investigate the relationship between marrow adipose tissue, bone mass and parathyroid hormone. The influence of osteocalcin on the homeostasis model assessment of insulin resistance was also evaluated. METHODS: This was a cross-sectional study conducted at a university hospital, involving 18 patients with primary hyperparathyroidism (PHPT) and 21 controls (CG). Bone mass was assessed by dual-energy x-ray absorptiometry and marrow adipose tissue was assessed by 1H magnetic resonance spectroscopy. The biochemical evaluation included the determination of parathyroid hormone, osteocalcin, glucose and insulin levels. RESULTS: A negative association was found between the bone mass at the 1/3 radius and parathyroid hormone levels (r = -0.69; p<0.01). Marrow adipose tissue was not significantly increased in patients (CG = 32.8±11.2% vs PHPT = 38.6±12%). The serum levels of osteocalcin were higher in patients (CG = 8.6±3.6 ng/mL vs PHPT = 36.5±38.4 ng/mL; p<0.005), but no associations were observed between osteocalcin and insulin or between insulin and both marrow adipose tissue and bone mass. CONCLUSION: These results suggest that the increment of adipogenesis in the bone marrow microenvironment under conditions of high bone turnover due to primary hyperparathyroidism is limited. Despite the increased serum levels of osteocalcin due to primary hyperparathyroidism, these patients tend to have impaired insulin sensitivity.
https://doi.org/10.6061/clinics/2016(08)09
755 downloads
9.
Sistema de Adquisición de Señales SEMG para la Detección de Fatiga Muscular
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Correa-Figueroa, J.L.
; Morales-Sánchez, E.
; Huerta-Ruelas, J.A.
; González-Barbosa, J.J.
; Cárdenas-Pérez, C.R.
.
Abstract This paper presents the development of a system for acquiring and processing of surface myoelectric signals or SEMG. The proposed system acquires signals SEMG skin surface using AgCl surface electrodes. The system has an amplification step and hardware filtering to streamline the processing time. Developed software for processing the Fourier transform SEMG amplified and filtered signal. Unlike other systems for acquisition of biological signals, which are developed for therapy or rehabilitation, this system is intended to be used for the control of robotic arms, so the software performs the measurement of fatigue using parameters like bleed average frequency and instantaneous power spectral density of the signal SEMG.
Resumen Este trabajo presenta el desarrollo de un sistema de adquisición y procesamiento de señales mioeléctricas superficiales o SEMG. El sistema propuesto adquiere las señales SEMG de la superficie de la piel utilizando electrodos superficiales de AgCl. El sistema tiene una etapa de amplificación y de filtrado por hardware para eficientar el tiempo de proceso. Se desarrolló un software para procesar por transformada de Fourier la señal SEMG amplificada y filtrada. A diferencia de otros sistemas de adquisición de señales biológicas que son desarrollados para terapia o rehabilitación, este sistema está pensado para ser usado para el control de brazos robóticos, por ello el software desarrollado mide la fatiga utilizando parámetros como el corrimiento de la frecuencia media instantánea y la densidad espectral de potencia de la señal SEMG.
https://doi.org/10.17488/RMIB.37.1.4
23457 downloads
10.
Nectandra falcifolia: potential phytopharmaceutical for skin damage protection designed by statistical approach and characterized by photoacoustic spectroscopy
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Borghi-Pangoni, Fernanda B.
; Tunin, Luana M.
; Bonifácio, Kamilla L.
; Nogueira, Ana Cláudia
; Hernandes, Luzmarina
; Yamashita, Fabio
; Barbosa, Décio S.
; Baesso, Mauro L.
; Truiti, Maria da Conceição T.
; Diniz, Andréa
.
AbstractPhytopharmaceutical products are being used in the treatment and prevention of health problems. Nowadays, the development and evaluation of novel pharmaceutical products is expensive and time consuming. A statistical approach is a good tool for optimal development processes. Nectandra falcifolia (Nees) J.A. Castigl. ex Mart. Crov. & Piccinini, Lauraceae, a Brazilian species, is reported as anti-inflammatory, anti-leishmanial and anti-microbial. However, there is little known about its chemical composition. For other species of Nectandra genus, the presence of antioxidant compounds is reported. In order to optimize the process of obtaining extract with high antioxidant activity, different extraction conditions were tested following a statistical approach. Two sequential experimental designs were used – first, a factorial 23 design, followed by central composite 22. The extracts manufactured by these experimental statistical matrixes had their antioxidant activity and phenolic contents quantified and the response surface plots were fitted in quadratic models and they predicted the best extraction condition for the best antioxidant activity. This standardized extract and its antioxidant activity were better evaluated by two complementary tests (ABTS and Burst respiratory). A topical formulation containing 1% (w/w) of standardized extract was prepared and used for an in vivo skin permeation study using a two-dose application. The photoacoustic spectroscopy was used to analyze the samples from the permeation study and the composition profile of standardized extract. In rat skin samples, the data demonstrated that for the higher dose of topical formulation (5 g/cm2), the standardized extract could cross skin and be seen in epidermis and dermis. This was not the case for the lower dose (2 g/cm2) which was only present in the epidermis. This information suggests that this novel standardized extract of N. falcifoliacould be explored for skin damage prevention or treatment for diseases developed by oxidative damage.
https://doi.org/10.1016/j.bjp.2015.02.012
930 downloads
11.
Growing knowledge: an overview of Seed Plant diversity in Brazil
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Zappi, Daniela C.
; Filardi, Fabiana L. Ranzato
; Leitman, Paula
; Souza, Vinícius C.
; Walter, Bruno M.T.
; Pirani, José R.
; Morim, Marli P.
; Queiroz, Luciano P.
; Cavalcanti, Taciana B.
; Mansano, Vidal F.
; Forzza, Rafaela C.
; Abreu, Maria C.
; Acevedo-Rodríguez, Pedro
; Agra, Maria F.
; Almeida Jr., Eduardo B.
; Almeida, Gracineide S.S.
; Almeida, Rafael F.
; Alves, Flávio M.
; Alves, Marccus
; Alves-Araujo, Anderson
; Amaral, Maria C.E.
; Amorim, André M.
; Amorim, Bruno
; Andrade, Ivanilza M.
; Andreata, Regina H.P.
; Andrino, Caroline O.
; Anunciação, Elisete A.
; Aona, Lidyanne Y.S.
; Aranguren, Yani
; Aranha Filho, João L.M.
; Araújo, Andrea O.
; Araújo, Ariclenes A.M.
; Araújo, Diogo
; Arbo, María M.
; Assis, Leandro
; Assis, Marta C.
; Assunção, Vivian A.
; Athiê-Souza, Sarah M.
; Azevedo, Cecilia O.
; Baitello, João B.
; Barberena, Felipe F.V.A.
; Barbosa, Maria R.V.
; Barros, Fábio
; Barros, Lucas A.V.
; Barros, Michel J.F.
; Baumgratz, José F.A.
; Bernacci, Luis C.
; Berry, Paul E.
; Bigio, Narcísio C.
; Biral, Leonardo
; Bittrich, Volker
; Borges, Rafael A.X.
; Bortoluzzi, Roseli L.C.
; Bove, Cláudia P.
; Bovini, Massimo G.
; Braga, João M.A.
; Braz, Denise M.
; Bringel Jr., João B.A.
; Bruniera, Carla P.
; Buturi, Camila V.
; Cabral, Elza
; Cabral, Fernanda N.
; Caddah, Mayara K.
; Caires, Claudenir S.
; Calazans, Luana S.B.
; Calió, Maria F.
; Camargo, Rodrigo A.
; Campbell, Lisa
; Canto-Dorow, Thais S.
; Carauta, Jorge P.P.
; Cardiel, José M.
; Cardoso, Domingos B.O.S.
; Cardoso, Leandro J.T.
; Carneiro, Camila R.
; Carneiro, Cláudia E.
; Carneiro-Torres, Daniela S.
; Carrijo, Tatiana T.
; Caruzo, Maria B.R.
; Carvalho, Maria L.S.
; Carvalho-Silva, Micheline
; Castello, Ana C.D.
; Cavalheiro, Larissa
; Cervi, Armando C.
; Chacon, Roberta G.
; Chautems, Alain
; Chiavegatto, Berenice
; Chukr, Nádia S.
; Coelho, Alexa A.O.P.
; Coelho, Marcus A.N.
; Coelho, Rubens L.G.
; Cordeiro, Inês
; Cordula, Elizabeth
; Cornejo, Xavier
; Côrtes, Ana L.A.
; Costa, Andrea F.
; Costa, Fabiane N.
; Costa, Jorge A.S.
; Costa, Leila C.
; Costa-e-Silva, Maria B.
; Costa-Lima, James L.
; Cota, Maria R.C.
; Couto, Ricardo S.
; Daly, Douglas C.
; De Stefano, Rodrigo D.
; De Toni, Karen
; Dematteis, Massimiliano
; Dettke, Greta A.
; Di Maio, Fernando R.
; Dórea, Marcos C.
; Duarte, Marília C.
; Dutilh, Julie H.A.
; Dutra, Valquíria F.
; Echternacht, Lívia
; Eggers, Lilian
; Esteves, Gerleni
; Ezcurra, Cecilia
; Falcão Junior, Marcus J.A.
; Feres, Fabíola
; Fernandes, José M.
; Ferreira, D.M.C.
; Ferreira, Fabrício M.
; Ferreira, Gabriel E.
; Ferreira, Priscila P.A.
; Ferreira, Silvana C.
; Ferrucci, Maria S.
; Fiaschi, Pedro
; Filgueiras, Tarciso S.
; Firens, Marcela
; Flores, Andreia S.
; Forero, Enrique
; Forster, Wellington
; Fortuna-Perez, Ana P.
; Fortunato, Reneé H.
; Fraga, Cléudio N.
; França, Flávio
; Francener, Augusto
; Freitas, Joelcio
; Freitas, Maria F.
; Fritsch, Peter W.
; Furtado, Samyra G.
; Gaglioti, André L.
; Garcia, Flávia C.P.
; Germano Filho, Pedro
; Giacomin, Leandro
; Gil, André S.B.
; Giulietti, Ana M.
; A.P.Godoy, Silvana
; Goldenberg, Renato
; Gomes da Costa, Géssica A.
; Gomes, Mário
; Gomes-Klein, Vera L.
; Gonçalves, Eduardo Gomes
; Graham, Shirley
; Groppo, Milton
; Guedes, Juliana S.
; Guimarães, Leonardo R.S.
; Guimarães, Paulo J.F.
; Guimarães, Elsie F.
; Gutierrez, Raul
; Harley, Raymond
; Hassemer, Gustavo
; Hattori, Eric K.O.
; Hefler, Sonia M.
; Heiden, Gustavo
; Henderson, Andrew
; Hensold, Nancy
; Hiepko, Paul
; Holanda, Ana S.S.
; Iganci, João R.V.
; Imig, Daniela C.
; Indriunas, Alexandre
; Jacques, Eliane L.
; Jardim, Jomar G.
; Kamer, Hiltje M.
; Kameyama, Cíntia
; Kinoshita, Luiza S.
; Kirizawa, Mizué
; Klitgaard, Bente B.
; Koch, Ingrid
; Koschnitzke, Cristiana
; Krauss, Nathália P.
; Kriebel, Ricardo
; Kuntz, Juliana
; Larocca, João
; Leal, Eduardo S.
; Lewis, Gwilym P.
; Lima, Carla T.
; Lima, Haroldo C.
; Lima, Itamar B.
; Lima, Laíce F.G.
; Lima, Laura C.P.
; Lima, Leticia R.
; Lima, Luís F.P.
; Lima, Rita B.
; Lírio, Elton J.
; Liro, Renata M.
; Lleras, Eduardo
; Lobão, Adriana
; Loeuille, Benoit
; Lohmann, Lúcia G.
; Loiola, Maria I.B.
; Lombardi, Julio A.
; Longhi-Wagner, Hilda M.
; Lopes, Rosana C.
; Lorencini, Tiago S.
; Louzada, Rafael B.
; Lovo, Juliana
; Lozano, Eduardo D.
; Lucas, Eve
; Ludtke, Raquel
; Luz, Christian L.
; Maas, Paul
; Machado, Anderson F.P.
; Macias, Leila
; Maciel, Jefferson R.
; Magenta, Mara A.G.
; Mamede, Maria C.H.
; Manoel, Evelin A.
; Marchioretto, Maria S.
; Marques, Juliana S.
; Marquete, Nilda
; Marquete, Ronaldo
; Martinelli, Gustavo
; Martins da Silva, Regina C.V.
; Martins, Ângela B.
; Martins, Erika R.
; Martins, Márcio L.L.
; Martins, Milena V.
; Martins, Renata C.
; Matias, Ligia Q.
; Maya-L., Carlos A.
; Mayo, Simon
; Mazine, Fiorella
; Medeiros, Debora
; Medeiros, Erika S.
; Medeiros, Herison
; Medeiros, João D.
; Meireles, José E.
; Mello-Silva, Renato
; Melo, Aline
; Melo, André L.
; Melo, Efigênia
; Melo, José I.M.
; Menezes, Cristine G.
; Menini Neto, Luiz
; Mentz, Lilian A.
; Mezzonato, A.C.
; Michelangeli, Fabián A.
; Milward-de-Azevedo, Michaele A.
; Miotto, Silvia T.S.
; Miranda, Vitor F.O.
; Mondin, Cláudio A.
; Monge, Marcelo
; Monteiro, Daniele
; Monteiro, Raquel F.
; Moraes, Marta D.
; Moraes, Pedro L.R.
; Mori, Scott A.
; Mota, Aline C.
; Mota, Nara F.O.
; Moura, Tania M.
; Mulgura, Maria
; Nakajima, Jimi N.
; Nardy, Camila
; Nascimento Júnior, José E.
; Noblick, Larry
; Nunes, Teonildes S.
; O'Leary, Nataly
; Oliveira, Arline S.
; Oliveira, Caetano T.
; Oliveira, Juliana A.
; Oliveira, Luciana S.D.
; Oliveira, Maria L.A.A.
; Oliveira, Regina C.
; Oliveira, Renata S.
; Oliveira, Reyjane P.
; Paixão-Souza, Bruno
; Parra, Lara R.
; Pasini, Eduardo
; Pastore, José F.B.
; Pastore, Mayara
; Paula-Souza, Juliana
; Pederneiras, Leandro C.
; Peixoto, Ariane L.
; Pelissari, Gisela
; Pellegrini, Marco O.O.
; Pennington, Toby
; Perdiz, Ricardo O.
; Pereira, Anna C.M.
; Pereira, Maria S.
; Pereira, Rodrigo A.S.
; Pessoa, Clenia
; Pessoa, Edlley M.
; Pessoa, Maria C.R.
; Pinto, Luiz J.S.
; Pinto, Rafael B.
; Pontes, Tiago A.
; Prance, Ghillean T.
; Proença, Carolyn
; Profice, Sheila R.
; Pscheidt, Allan C.
; Queiroz, George A.
; Queiroz, Rubens T.
; Quinet, Alexandre
; Rainer, Heimo
; Ramos, Eliana
; Rando, Juliana G.
; Rapini, Alessandro
; Reginato, Marcelo
; Reis, Ilka P.
; Reis, Priscila A.
; Ribeiro, André R.O.
; Ribeiro, José E.L.S.
; Riina, Ricarda
; Ritter, Mara R.
; Rivadavia, Fernando
; Rocha, Antônio E.S.
; Rocha, Maria J.R.
; Rodrigues, Izabella M.C.
; Rodrigues, Karina F.
; Rodrigues, Rodrigo S.
; Rodrigues, Rodrigo S.
; Rodrigues, Vinícius T.
; Rodrigues, William
; Romaniuc Neto, Sérgio
; Romão, Gerson O.
; Romero, Rosana
; Roque, Nádia
; Rosa, Patrícia
; Rossi, Lúcia
; Sá, Cyl F.C.
; Saavedra, Mariana M.
; Saka, Mariana
; Sakuragui, Cássia M.
; Salas, Roberto M.
; Sales, Margareth F.
; Salimena, Fatima R.G.
; Sampaio, Daniela
; Sancho, Gisela
; Sano, Paulo T.
; Santos, Alessandra
; Santos, Élide P.
; Santos, Juliana S.
; Santos, Marianna R.
; Santos-Gonçalves, Ana P.
; Santos-Silva, Fernanda
; São-Mateus, Wallace
; Saraiva, Deisy P.
; Saridakis, Dennis P.
; Sartori, Ângela L.B.
; Scalon, Viviane R.
; Schneider, Ângelo
; Sebastiani, Renata
; Secco, Ricardo S.
; Senna, Luisa
; Senna-Valle, Luci
; Shirasuna, Regina T.
; Silva Filho, Pedro J.S.
; Silva, Anádria S.
; Silva, Christian
; Silva, Genilson A.R.
; Silva, Gisele O.
; Silva, Márcia C.R.
; Silva, Marcos J.
; Silva, Marcos J.
; Silva, Otávio L.M.
; Silva, Rafaela A.P.
; Silva, Saura R.
; Silva, Tania R.S.
; Silva-Gonçalves, Kelly C.
; Silva-Luz, Cíntia L.
; Simão-Bianchini, Rosângela
; Simões, André O.
; Simpson, Beryl
; Siniscalchi, Carolina M.
; Siqueira Filho, José A.
; Siqueira, Carlos E.
; Siqueira, Josafá C.
; Smith, Nathan P.
; Snak, Cristiane
; Soares Neto, Raimundo L.
; Soares, Kelen P.
; Soares, Marcos V.B.
; Soares, Maria L.
; Soares, Polyana N.
; Sobral, Marcos
; Sodré, Rodolfo C.
; Somner, Genise V.
; Sothers, Cynthia A.
; Sousa, Danilo J.L.
; Souza, Elnatan B.
; Souza, Élvia R.
; Souza, Marcelo
; Souza, Maria L.D.R.
; Souza-Buturi, Fátima O.
; Spina, Andréa P.
; Stapf, María N.S.
; Stefano, Marina V.
; Stehmann, João R.
; Steinmann, Victor
; Takeuchi, Cátia
; Taylor, Charlotte M.
; Taylor, Nigel P.
; Teles, Aristônio M.
; Temponi, Lívia G.
; Terra-Araujo, Mário H.
; Thode, Veronica
; Thomas, W.Wayt
; Tissot-Squalli, Mara L.
; Torke, Benjamin M.
; Torres, Roseli B.
; Tozzi, Ana M.G.A.
; Trad, Rafaela J.
; Trevisan, Rafael
; Trovó, Marcelo
; Valls, José F.M.
; Vaz, Angela M.S.F.
; Versieux, Leonardo
; Viana, Pedro L.
; Vianna Filho, Marcelo D.M.
; Vieira, Ana O.S.
; Vieira, Diego D.
; Vignoli-Silva, Márcia
; Vilar, Thaisa
; Vinhos, Franklin
; Wallnöfer, Bruno
; Wanderley, Maria G.L.
; Wasshausen, Dieter
; Watanabe, Maurício T.C.
; Weigend, Maximilian
; Welker, Cassiano A.D.
; Woodgyer, Elizabeth
; Xifreda, Cecilia C.
; Yamamoto, Kikyo
; Zanin, Ana
; Zenni, Rafael D.
; Zickel, Carmem S
.
Resumo Um levantamento atualizado das plantas com sementes e análises relevantes acerca desta biodiversidade são apresentados. Este trabalho se iniciou em 2010 com a publicação do Catálogo de Plantas e Fungos e, desde então vem sendo atualizado por mais de 430 especialistas trabalhando online. O Brasil abriga atualmente 32.086 espécies nativas de Angiospermas e 23 espécies nativas de Gimnospermas e estes novos dados mostram um aumento de 3% da riqueza em relação a 2010. A Amazônia é o Domínio Fitogeográfico com o maior número de espécies de Gimnospermas, enquanto que a Floresta Atlântica possui a maior riqueza de Angiospermas. Houve um crescimento considerável no número de espécies e nas taxas de endemismo para a maioria dos Domínios (Caatinga, Cerrado, Floresta Atlântica, Pampa e Pantanal), com exceção da Amazônia que apresentou uma diminuição de 2,5% de endemicidade. Entretanto, a maior parte das plantas com sementes que ocorrem no Brasil (57,4%) é endêmica deste território. A proporção de formas de vida varia de acordo com os diferentes Domínios: árvores são mais expressivas na Amazônia e Floresta Atlântica do que nos outros biomas, ervas são dominantes no Pampa e as lianas apresentam riqueza expressiva na Amazônia, Floresta Atlântica e Pantanal. Este trabalho não só quantifica a biodiversidade brasileira, mas também indica as lacunas de conhecimento e o desafio a ser enfrentado para a conservação desta flora.
Abstract An updated inventory of Brazilian seed plants is presented and offers important insights into the country's biodiversity. This work started in 2010, with the publication of the Plants and Fungi Catalogue, and has been updated since by more than 430 specialists working online. Brazil is home to 32,086 native Angiosperms and 23 native Gymnosperms, showing an increase of 3% in its species richness in relation to 2010. The Amazon Rainforest is the richest Brazilian biome for Gymnosperms, while the Atlantic Rainforest is the richest one for Angiosperms. There was a considerable increment in the number of species and endemism rates for biomes, except for the Amazon that showed a decrease of 2.5% of recorded endemics. However, well over half of Brazillian seed plant species (57.4%) is endemic to this territory. The proportion of life-forms varies among different biomes: trees are more expressive in the Amazon and Atlantic Rainforest biomes while herbs predominate in the Pampa, and lianas are more expressive in the Amazon, Atlantic Rainforest, and Pantanal. This compilation serves not only to quantify Brazilian biodiversity, but also to highlight areas where there information is lacking and to provide a framework for the challenge faced in conserving Brazil's unique and diverse flora.
https://doi.org/10.1590/2175-7860201566411
33340 downloads
12.
Distribuição espacial de acidentes escorpiônicos em Belo Horizonte, Minas Gerais, 2005 a 2009
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Barbosa, A.D.
; Silva, J.A.
; Cardoso, M.F.E.C.
; Meneses, J.N.C.
; Cunha, M.C.M.
; Haddad, J.P.A.
; Nicolino, R.R.
; Magalhães, D.F.
.
Arquivo Brasileiro de Medicina Veterinária e Zootecnia
- Journal Metrics
Acidentes por escorpião constituem problema de saúde pública em Belo Horizonte. Realizou-se um estudo epidemiológico observacional retrospectivo para analisar a frequência e distribuição espacial dos acidentes escorpiônicos em Belo Horizonte, entre 2005 e 2009, e associá-las às categorias de risco classificadas pelo Índice de Vulnerabilidade à Saúde (IVS), um índice socioeconômico regional composto. Foram utilizados dados de notificação do Sistema Nacional de Agravos de Notificação (SINAN) e Sistema de Vigilância Epidemiológica (SISVE), referentes aos anos de 2008 e 2009. Para o período de 2005 a 2007, foi necessário o resgate de dados das fichas clínicas do Hospital João XXIII (HPSJXXIII) correspondentes às variáveis encontradas no SINAN e SISVE, uma vez que os mesmos não estavam digitalizados nos referidos sistemas de informação. Para georreferenciamento e análise espacial, foi utilizada a base geográfica EndGeo, o aplicativo de mapeamento MapInfo versão 10.0 e os programas Hotspot Detective e SatScan. Entre 2005 e 2009, ocorreram em Belo Horizonte 2.769 casos de acidentes por escorpião, o que representa uma incidência média de 22,4 casos por 100.000 habitantes. Do total de casos, 1.924 (69,5%) foram georreferenciados e houve predomínio de incidência em dois Distritos Sanitários (DS), com grande concentração de casos nas regiões de cemitérios do município. Foram detectados dois "clusters" no período, sendo um em 2005, nos DS Noroeste e Oeste, e outro entre 2006 e 2007, nos DS Noroeste e Nordeste. Não houve associação entre as áreas de maior incidência de escorpionismo e as áreas de maior risco à saúde classificadas pelo IVS. Com base nos resultados, conclui-se que há necessidade de melhorias no processo de notificação do agravo e que o mapeamento dos casos é uma ferramenta relevante capaz de embasar o direcionamento das ações educativas de controle para as áreas prioritárias de Belo Horizonte.
Scorpion sting accidents are a public health problem in Belo Horizonte and veterinarians play an important role in its control program when based on capture, mapping of cases and educational actions with the population. A retrospective epidemiological study was done to analyze the frequency and spatial distribution of scorpion sting cases in Belo Horizonte, between 2005 and 2009, and to associate them with the Health Vulnerability Index (IVS), a regional and composed socio-economic index. Notification data of scorpion sting accidents were used from the National System of Notifiable Diseases (SINAN) and Epidemiological Surveillance System (SISVE) for years 2008 and 2009. For the period between 2005 and 2007 it was necessary to retrieve data from the clinical records of João XXIII Hospital (HPSJ XXIII) which were not digitalized in the referred information systems. For georeference and spatial analysis, geographic base EndGeo and features of the programs MapInfo version 10.0, Hotspot Detective and SatScan were used. Between 2005 and 2009 2769 cases of scorpionism, occurred in Belo Horizonte which represents an average incidence of 22.4 cases per 100,000 inhabitants. Among 1924 (69.5%) georeferenced cases, the highest incidence was observed in two Sanitary District (DS). A large concentration of cases was also observed in the areas of the city cemeteries. Two clusters were detected during this period, one in 2005, located in the Northwest and West DS, and another between 2006 and 2007 in the Northwest and Northeast DS. There was no association between higher incidence areas of scorpionism in Belo Horizonte and the areas of higher health risk classified by IVS. It is necessary to improve the reporting process regarding scorpion sting accidents. Another conclusion is that the mapping of cases is a relevant tool to base the targeting of educative actions to the priority areas of Belo Horizonte.
https://doi.org/10.1590/16784162-7116
4090 downloads
13.
Dynamics of chest wall volume regulation during constant work rate exercise in patients with chronic obstructive pulmonary disease
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Takara, L.S.
; Cunha, T.M.
; Barbosa, P.
; Rodrigues, M.K.
; Oliveira, M.F.
; Nery, L.E.
; Neder, J.A.
.
Brazilian Journal of Medical and Biological Research
- Journal Metrics
This study evaluated the dynamic behavior of total and compartmental chest wall volumes [(V CW) = rib cage (V RC) + abdomen (V AB)] as measured breath-by-breath by optoelectronic plethysmography during constant-load exercise in patients with stable chronic obstructive pulmonary disease. Thirty males (GOLD stages II-III) underwent a cardiopulmonary exercise test to the limit of tolerance (Tlim) at 75% of peak work rate on an electronically braked cycle ergometer. Exercise-induced dynamic hyperinflation was considered to be present when end-expiratory (EE) V CW increased in relation to resting values. There was a noticeable heterogeneity in the patterns of V CW regulation as EEV CW increased non-linearly in 17/30 "hyperinflators" and decreased in 13/30 "non-hyperinflators" (P < 0.05). EEV AB decreased slightly in 8 of the "hyperinflators", thereby reducing and slowing the rate of increase in end-inspiratory (EI) V CW (P < 0.05). In contrast, decreases in EEV CW in the "non-hyperinflators" were due to the combination of stable EEV RC with marked reductions in EEV AB. These patients showed lower EIV CW and end-exercise dyspnea scores but longer Tlim than their counterparts (P < 0.05). Dyspnea increased and Tlim decreased non-linearly with a faster rate of increase in EIV CW regardless of the presence or absence of dynamic hyperinflation (P < 0.001). However, no significant between-group differences were observed in metabolic, pulmonary gas exchange and cardiovascular responses to exercise. Chest wall volumes are continuously regulated during exercise in order to postpone (or even avoid) their migration to higher operating volumes in patients with COPD, a dynamic process that is strongly dependent on the behavior of the abdominal compartment.
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Cited 1 time in SciELO
14.
Insulina pancreática de ratos diabéticos tipo 1 submetidos a um protocolo de treinamento físico individualizado
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Moura, L. Pereira de
; Gomes, R.J.
; Leme, J.A.
; Voltarelli, F.A.
; Ribeiro, C.
; Moura, R. Ferreira de
; Araújo, M. Barbosa de
; Luciano, E.
; Mello, M. Rostom de
.
Dado que o diabetes mellitus é considerado um problema de saúde pública mundial, o presente estudo objetivou avaliar a tolerância à glicose oral (TTGo) e concentrações de insulina pancreática (CIP) de ratos diabéticos tipo 1 submetidos a um protocolo de treinamento físico individualizado. Foram utilizados 40 ratos Wistar adultos, onde metade foi induzida ao diabetes por meio de injeção endovenosa de aloxana (32 mg/kg), divididos em quatro grupos (10 por grupo): Controle Sedentário (CS), Controle Treinado (CT), Diabético Sedentário (DS) e Diabético Treinado (DT). O treinamento físico consistiu de natação, 1 h/dia, 5 dias/semana durante 8 semanas, com sobrecarga equivalente a 90% da transição metabólica aeróbia/anaeróbia determinada no início do experimento. Os ratos dos grupos DS e DT apresentaram redução de peso corporal em relação aos controles, a qual foi menos acentuada no grupo DT. As ingestões hídrica e alimentar aumentaram nos grupos diabéticos em relação aos controles. Durante o TTGo, os valores de área sob a curva glicêmica dos grupos diabéticos foram superiores aos dos controles. O treinamento físico atenuou esta elevação. Os grupos diabéticos apresentaram CIP reduzida quando comparados aos grupos controles. O protocolo de treinamento físico empregado, embora não tenha alterado a CIP, melhorou a homeostase glicêmica e atenuou a perda de peso corporal dos animais diabéticos.
Since diabetes mellitus is considered a world public health problem, the present study aimed to evaluate oral glucose tolerance (TTGo) and pancreatic insulin concentration (PIC) of type I diabetic rats subjected to an individualized exercise training protocol. A total of 40 adult Wistar rats were used, half of which induced to diabetes by alloxan (32 mg/kg) endovenous injection, and divided into four groups (10 per group): Sedentary Control (SC), Trained Control (TC), Sedentary Diabetic (SD) and Trained Diabetic (TD). The physical training consisted of swimming, 1 h/day, 5 days/week during 8 weeks, supporting overload equivalent to 90% of the individual anaerobic/aerobic metabolic transition determined at the beginning of the experiment. The rats of SD and TD groups presented body weight reduction in relation to controls, which was less accentuated in TD group. Water and food ingestion increased in the diabetic groups in relation to controls. The areas under the serum glucose curve during the GTTo of diabetic groups were higher than the controls. Physical training attenuated this elevation. The diabetic groups showed reduced PIC when compared to both control groups. The physical training protocol employed improved glucose homeostasis and attenuated the body weight loss of diabetic animals but did not alter pancreatic insulin concentration.
https://doi.org/10.6063/motricidade.8(1).234
2121 downloads
15.
Sincronização da ovulação utilizando FSH em substituição à eCG em cabras
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Souza, R.S.
; Barbosa, L.P.
; Aguiar, C.S.
; Figueredo Júnior, J.
; Ribeiro, M.O.
; Mendes, C.S
; Almeida, V.F.
; Araújo, R.C.S.A.
; Pinheiro, A.M.
; Marques, J.A.
.
Arquivo Brasileiro de Medicina Veterinária e Zootecnia
- Journal Metrics
The effect of substitution of equine chorionic gonadotropin (eCG) by follicle stimulating hormone (FSH) in synchronization protocols of ovulation in dairy goats was evaluated. Twelve goats received intravaginal sponges impregnated with 60mg of medroxyprogesterone acetate (MAP) for 10 days. The sponges were removed and the animals were distributed into two groups (G): G1 (n=6) treated with 0.5mL of a synthetic analogue of PGF2 α and 100 IU of eCG for each 10kg weight, intramuscular injection (IM); and G2 (n=6) treated with 0.5mL of a synthetic analogue of PGF2α and 20mg of FSH (IM). All animals were monitored for estrus detection with aid of a ruffian after sponge removal. The ovarian dynamics were analyzed by ultrasound, since six hours after sponge removed. Each animal was analyzed in time elapsed of six hours until 12 hours after ovulation detection. For data analyses, the Wilcoxon test and variance analyses were used. There was not difference between the analyzed parameters (P>0.05). In this way, eCG can be replaced by FSH in synchronization protocols of ovulation in dairy goats.
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