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1.
Chemical Characterization and Evaluation of the Anti-Cancer Potential of Flowers from Fridericia platyphylla (Bignoniaceae) AntiCancer Anti Cancer Bignoniaceae (Bignoniaceae
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Rosário, Marcelino S. do
; Mannochio-Russo, Helena
; Santos, Ana L. P. dos
; Pinheiro, Aglaete A.
Vasconcelos, Luna N.
Santos, Ana Paula S. A.
Oliveira, Lila T. de
Martins, Monique M.
Andrade, Marcelo S. de
Nascimento, Maria D. S. B.
Bolzani, Vanderlan S.
Lima, Josélia A.
Rocha, Cláudia Q. da



In this study, we aimed to investigate the anticancer activity of the extract, fractions, and isolated compounds of the flowers of Fridericia platyphylla, and to characterize the bioactive compounds. The chemical diversity of the extracts and fractions was investigated using liquid chromatography coupled with high resolution mass spectrometry (LC-HRMS). We were able to annotate 26 compounds from the classes of flavones, flavonols, flavanones, isoflavones, and cinnamic acid and its derivatives. The dichloromethane fraction showed greater cytotoxicity at a concentration of 100 µg mL−1. In addition, the inhibitory concentrations of the dichloromethane fraction were 22.14 and 30.9 µg mL−1 for MCF-7 and MDA-MB-231 cell lines, respectively, and were capable of inhibiting tumor cell migration. Brachydins A and C were isolated from the dichloromethane fraction and showed the greatest cytotoxicity. The results obtained from this study show the potential biological effect of F. platyphylla flowers as a possible antitumor pharmacological agent. extract LCHRMS. LCHRMS LC HRMS . (LC-HRMS) 2 flavones flavonols flavanones isoflavones derivatives 10 mL1 mL 1 addition 2214 22 14 22.1 309 30 9 30. mL− MCF7 MCF 7 MCF- MDAMB231 MDAMB MDA MB 231 MDA-MB-23 lines respectively migration F agent (LC-HRMS 221 22. 3 MDAMB23 23 MDA-MB-2 MDAMB2 MDA-MB- MDA-MB
2.
In vitro and in silico Antifungal Activity of Metabolites from Bredemeyera brevifolia (Benth.) Klotzsch ex A.W. Benn. Benth. Benth (Benth. AW A W A.W Benn (Benth
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Barreto, Rubens S.
; Costa, Diego M. da
; Sousa, Jailan S.
; Jesus, Vilisaimon S. de
; Silva, Agnaldo P. da
; Buonafina-Paz, Maria Daniela S.
; Santos, Franz A. G. dos
; Neves, Rejane P.
; Pastore, José F. B.
; Andrade, Bruno S.
; Soares, Wagner R. A.
; Brandão, Hugo N.
; Aguiar, Rosane M.
; Alves, Clayton Q.
.














Bredemeyera Willd. is a genus of the Polygalaceae family, occurring in Brazil. This research aims to evaluate the phytochemical and antifungal potential, in vitro and in silico, of Bredemeyera brevifolia extracts. The identification of fatty acids by gas chromatography-mass spectrometry and their quantification by gas chromatography-flame ionization detector showed that palmitic (36.55 mg g−1), margaric (3.66 mg g−1), linolelaidic (108.82 mg g−1), oleic (7.86 mg g−1), stearic (41.11 mg g−1), dihomo-γ-linolenic (85.48 mg g−1), and arachidic (209.00 mg g−1) acids are present in the hexane extract. From the chloroform extract, 1-hydroxy-3,7-dimethoxyxanthone was isolated and identified. The minimum inhibitory concentration assay with methanolic extract demonstrated antifungal activity against species of the genus Candida, Sporothrix, and Trichophyton for up to 96 h, with values ranging from 64-1024 μg mL−1. The in silico study with the chemical compounds of this species showed fungal inhibition potential of sterol-14-α-demethylase, highlighting 1-hydroxy-3,7-dimethoxyxanthone, which presented an affinity energy of -8.8 kcal mol−1, greater than that observed for fluconazole (−8.3 kcal mol−1). The fatty acids interacted with the active site of the enzyme but presented energies ≥ −7.4 kcal mol−1. Compounds isolated from this species have pharmacokinetic potential for the development of pharmaceutical formulations. Willd family Brazil extracts chromatographymass chromatography mass chromatographyflame flame 36.55 3655 36 55 (36.5 g−1, g1 g g−1 , 1 3.66 366 3 66 (3.6 108.82 10882 108 82 (108.8 7.86 786 7 86 (7.8 41.11 4111 41 11 (41.1 dihomoγlinolenic dihomo γ linolenic 85.48 8548 85 48 (85.4 209.00 20900 209 00 (209.0 1hydroxy3,7dimethoxyxanthone 1hydroxy37dimethoxyxanthone hydroxydimethoxyxanthone hydroxy 3,7 dimethoxyxanthone identified Candida Sporothrix 9 h 641024 64 1024 64-102 mL1 mL mL−1 sterol14αdemethylase, sterol14αdemethylase sterolαdemethylase sterol 14 α demethylase, demethylase sterol-14-α-demethylase 1hydroxy3,7dimethoxyxanthone, dimethoxyxanthone, 8.8 88 8 -8. mol1 mol mol−1 −8.3 83 (−8. . mol−1) 74 4 −7. formulations 36.5 365 5 (36. g− 3.6 6 (3. 108.8 1088 10 (108. 7.8 78 (7. 41.1 411 (41. 85.4 854 (85. 209.0 2090 20 0 (209. 1hydroxy3 7dimethoxyxanthone 37 3, 64102 102 64-10 mL− αdemethylase 8. -8 mol− −8. (−8 −7 36. (36 3. (3 108. (108 7. (7 41. (41 85. (85 209. 2 (209 1hydroxy 6410 64-1 - −8 (− − ( (10 (4 (8 (20 641 64- (1 (2
3.
Chemical Composition and Larvicidal Activity of Essential Oil Extracted from Anemia tomentosa (SAV.) Sw: Study Conducted in vitro and in silico SAV. SAV (SAV. Sw (SAV
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Jesus, Vilisaimon S. de
; Leite, Juliana L.
; Sousa, Jailan S.
; Barbosa, Fabricio S.
; Oliveira, Djalma M. de
; Barreto, Rubens S.
Soares, Wagner R. A.
Andrade, Bruno S.
Gualberto, Simone A.
Silva, Débora C. da
Guimarães, Isabelly D. S.
Silva, Luiza F.
Aguiar, Rosane M.





The essential oil extracted from Anemia tomentosa (EOAT) has shown larvicidal potential against Aedes aegypti, based on methods in vitro and in silico. Chromatographic and spectrometric techniques (gas chromatography-mass spectrometry (CG-MS), gas chromatography-flame ionization detector (GC-FID)), as well as mono and bidimensional nuclear magnetic resonance spectroscopy (NMR) were used to assess 10 essential oil components. Chemical composition of essential oil comprised 87.51% sesquiterpenes, with emphasis on presilphiperfolan-1-ol (42.13%) and silphiperfol-5-ene (19.47%). Larvicidal assay conducted in vitro with EOAT has evidenced potential cytotoxic activity up to 48 h exposure to it; mortality rate observed for A. aegypti larvae exposed to essential oil reached 100%. Study conducted in silico with chemical compounds deriving from the herein investigated plant species has evidenced its potential to inhibit acetylcholinesterase in A. aegypti. Activity of triquinane sesquiterpenes ranging from -6.8 to -8.2 kcal mol-1 stood out in comparison to that of temephos (-7.5 kcal mol-1). Chemical compounds identified in the investigated essential oil presented low human and environmental toxicity, as observed in absorption, distribution, metabolism and excretion, and toxicity (ADMETox) predictions. (EOAT chromatographymass chromatography mass CGMS, CGMS CG MS , (CG-MS) chromatographyflame flame GCFID, GCFID GC FID (GC-FID)) NMR (NMR 1 components 8751 87 51 87.51 presilphiperfolan1ol presilphiperfolanol presilphiperfolan ol 42.13% 4213 42 13 (42.13% silphiperfol5ene silphiperfolene silphiperfol 5 ene 19.47%. 1947 19.47% . 19 47 (19.47%) 4 it A 100 100% 6.8 68 6 8 -6. 8.2 82 2 -8. mol1 mol mol- 7.5 75 7 (-7. mol1. mol-1) absorption distribution excretion ADMETox (ADMETox predictions (CG-MS (GC-FID) 875 87.5 42.13 421 (42.13 194 19.47 (19.47% 6. -6 8. -8 7. (-7 (GC-FID 87. 42.1 (42.1 19.4 (19.47 - (- 42. (42. 19. (19.4 ( (42 (19. (4 (19 (1
4.
Inference of stature using segmental measures in comparison with directly measured height in children and adolescents: an analytical cross-sectional study adolescents crosssectional cross sectional
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Negrão, Isabela Lima
; Andrade, Márcia Reimol de
; Rodrigues, José Carlos R.
; Serapião, Yasmim de França S.
; Damázio, Laila Cristina M.
; Lamounier, Joel Alves
; Tibúrcio, Jacqueline Domingues
.







Abstract Objectives In the clinical routine of pediatricians, height is the most reliable indicator for assessing growth. However, there are situations where it is not possible to measure this parameter directly, making the estimation of height or length a useful alternative. The main goal of this study is to identify which segmental measure, including upper arm length (UAL), tibial length (TL), and knee-heel length (KHL), provides the stature estimate that most closely approximates directly measured height in the study participants. Methods Analytical cross-sectional study of the anthropometric and segmental measures of 248 participants, aged 0 to 14 years old, using Stevenson's and Kihara's equations to estimate indirectly measured height. Results The segmental measure that provided a measurement that deviated the least from the actual height was the KHL, followed by TL, both calculated using Stevenson's equations. Conclusion The use of segmental measures to infer a child's stature is valuable in clinical practice, particularly in bedridden and incapacitated patients. Based on the present findings, the KHL and TL segments yielded more accurate results than the UAL pediatricians growth However alternative UAL, , (UAL) (TL) kneeheel knee heel (KHL) participants crosssectional cross sectional 24 1 old Stevensons Stevenson s Kiharas Kihara childs child practice patients findings (UAL (TL (KHL 2
5.
Exercise prescriptions for patients on hemodialysis in Brazil: a scoping review Brazil
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Ribeiro, Heitor S.
; Andrade, Francini P.
; Leal, Diogo V.
; Oliveira, Juliana S.
; Wilund, Kenneth R.
; Reboredo, Maycon M.
; Viana, João L.
.







Resumo Introdução: O exercício físico está sendo incorporado ao tratamento de pacientes em hemodiálise, porém pouco se sabe sobre as principais características dessas intervenções. Objetivo: Descrever os protocolos de exercício físico prescritos para pacientes em hemodiálise no Brasil. Métodos: Uma revisão de escopo foi conduzida de acordo com as diretrizes JBI e Prisma-ScR. Foram realizadas pesquisas na Medline, Embase e em outras três bases de dados até maio de 2024. Outras fontes (sites, livros e diretrizes) também foram pesquisadas. Foram incluídas evidências de pacientes em hemodiálise, descrevendo protocolos de exercício físico em todos os ambientes e desenhos no Brasil. Resultados: Encontradas 45 evidências, resultando em 54 protocolos de exercício físico de 16 estados brasileiros. O exercício de força (33,3%), seguido do exercício aeróbico (22,2%), foi o mais prescrito para ser realizado durante a diálise (85,2%). Os profissionais mais prevalentes na supervisão dos programas foram fisioterapeutas e profissionais de educação física (37,0% e 18,5%, respectivamente). Todos os protocolos adotaram os princípios de treinamento tipo e frequência, enquanto a progressão foi adotada em apenas 53,7%. A frequência mais prescrita foi três vezes por semana (88,9%). A intensidade do exercício foi determinada predominantemente por métodos subjetivos (33,3%). Conclusão: Os exercícios aeróbicos e de força durante a diálise foram as modalidades mais prescritas no Brasil, com a maioria dos programas sendo adequadamente supervisionada por profissionais qualificados. No entanto, os protocolos existentes não adotaram a progressão sistemática no decorrer da intervenção, o que seria adequado para proporcionar melhores respostas e adaptações fisiológicas. Introdução intervenções Objetivo Brasil Métodos PrismaScR. PrismaScR Prisma ScR. ScR Prisma-ScR Medline 2024 sites, sites (sites pesquisadas Resultados 4 5 1 brasileiros 33,3%, 333 33,3% , 33 3 (33,3%) 22,2%, 222 22,2% 22 2 (22,2%) 85,2%. 852 85,2% . 85 (85,2%) 37,0% 370 37 0 (37,0 185 18 18,5% respectivamente. respectivamente respectivamente) 537 53 7 53,7% 88,9%. 889 88,9% 88 9 (88,9%) 33,3%. Conclusão qualificados entanto intervenção fisiológicas 202 33,3 (33,3% 22,2 (22,2% 85,2 8 (85,2% 37,0 (37, 18,5 53,7 88,9 (88,9% 20 33, (33,3 22, (22,2 85, (85,2 37, (37 18, 53, 88, (88,9 (33, (22, (85, (3 (88, (33 (22 (85 ( (88 (2 (8
Abstract Introduction: Exercise is being incorporated into the treatment of patients on hemodialysis; however, little is known about the major characteristics of these interventions. Objective: To describe the exercise protocols prescribed for hemodialysis patients in Brazil. Methods: A scoping review was conducted following JBI and Prisma-ScR guidelines. Searches were carried out in Medline, Embase and three other databases until May 2024. Other sources (websites, books and guidelines) were also investigated. Evidence from patients on hemodialysis describing exercise protocols in all settings and designs in Brazil was included. Results: Forty-five pieces of evidence were found, resulting in 54 exercise protocols from 16 Brazilian states. Strength exercises (33.3%), followed by aerobic exercises (22.2%), were the most prescribed, mainly to be performed during dialysis (85.2%). The most prevalent professionals supervising the programs were physiotherapists and exercise physiologists (37.0% and 18.5%, respectively). All protocols implemented the principles of type and frequency training, while progression was adopted in only 53.7%. The main prescription was three times per week (88.9%). Exercise intensity was predominantly determined by subjective methods (33.3%). Conclusion: Aerobic and strength exercises during dialysis were the most commonly prescribed modalities in Brazil, with the majority of programs being properly supervised by qualified professionals. However, existing protocols have not employed systematic progression throughout the intervention, which would be appropriate for providing better physiological responses and adaptations. Introduction however interventions Objective Methods PrismaScR Prisma ScR guidelines Medline 2024 websites, websites (websites investigated included Results Fortyfive Forty five found 5 1 states 33.3%, 333 33.3% , 33 3 (33.3%) 22.2%, 222 22.2% 22 2 (22.2%) 85.2%. 852 85.2% . 85 (85.2%) 37.0% 370 37 0 (37.0 185 18 18.5% respectively. respectively respectively) training 537 53 7 53.7% 88.9%. 889 88.9% 88 9 (88.9%) 33.3%. Conclusion However intervention adaptations 202 33.3 (33.3% 22.2 (22.2% 85.2 8 (85.2% 37.0 (37. 18.5 53.7 88.9 (88.9% 20 33. (33.3 22. (22.2 85. (85.2 37. (37 18. 53. 88. (88.9 (33. (22. (85. (3 (88. (33 (22 (85 ( (88 (2 (8
6.
Biostimulant for sugarcane ripening in drip fertigated fields
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Silva, Larissa B. da
; Santos, Crissogno M. dos
; Andrade, Joel J. de
; Lima, Amanda M. S. de
; Rego, Acsa E. de B.
; Oliveira, Emídio C. A. de
; Silva, Lilian H. A. da
.







Revista Brasileira de Engenharia Agrícola e Ambiental
- Journal Metrics
RESUMO Em ambientes irrigados, o crescimento vegetativo da cana-de-açúcar e o consumo de carboidratos durante a maturação requerem o manejo de maturadores para aumentar a produtividade da cultura. A combinação de maturadores, com nutrientes e bioestimulantes como os aminoácidos, pode promover respostas fisiológicas que favorecem a qualidade da matéria-prima e aumentam o teor de sacarose. Dessa forma, o estudo teve como objetivo avaliar a resposta agroindustrial da cultura de cana-de-açúcar fertirrigada aos agentes de maturação. Os tratamentos consistiram na aplicação de maturador químico (MQ), nutricional (MN), aplicação conjunta de MN+MQ e controle com quatro repetições. Os atributos agroindustriais (sólidos solúveis totais, sacarose aparente (AS), açúcares redutores (AR), açúcares totais recuperáveis (ATR), pureza, fibra, sacarose no colmo (SS) foram avaliados em 0 (antes da aplicação), 12, 19, 36 e 60 dias após aplicação (DAA). O tempo modificou os atributos tecnológicos da cana-de-açúcar sob aplicação de maturador. Os maiores valores de caldo AS e sólidos solúveis totais foram obtidos no MN+MQ em relação ao controle. Os tratamentos MN e MN+MQ apresentaram os maiores teores de ATR (150 kg Mg-1), aos 36 DAA. Além disso, o tratamento MN+MQ aumentou o teor de fibra, mas não comprometeu a qualidade da matéria-prima, e apresentou altos teores de SC e pureza, bem como baixos teores de AR. Os maturadores químicos e nutricionais foram eficientes em promover o amadurecimento da cana-de-açúcar em áreas sem secagem antes da colheita. A aplicação de MN no final do ciclo tem potencial para aumentar a produtividade de açúcar. irrigados canadeaçúcar cana açúcar aminoácidos matériaprima matéria prima forma MQ, MQ , (MQ) MN, (MN) MNMQ repetições AS, (AS) AR, AR (AR) ATR, (ATR) pureza fibra SS (SS aplicação, aplicação) 12 19 3 6 DAA . (DAA) 150 (15 Mg1, Mg1 Mg 1 Mg-1) disso matériaprima, prima, colheita (MQ (MN (AS (AR (ATR (DAA 15 (1 Mg-1 ( Mg-
ABSTRACT In irrigated fields, sugarcane’s vegetative growth and carbohydrate consumption during ripening require ripener management options to improve crop yield. The hypothesis is that ripeners, together with nutrients, biostimulants, and amino acids, improve physiological responses that favor the quality of the raw material and increase the sucrose content. Consequently, the study aimed to evaluate the agro-industrial response of a fertigated sugarcane crop to ripening agents. The treatments consisted of applying chemical ripener (CR), nutritional ripener (NR), and a joint application of NR+CR, besides control with four replicates. Agro-industrial attributes (total soluble solids, apparent sucrose (AS), reducing sugars (RS), total recoverable sugar (TRS), purity, fiber, sucrose in the stalk (SS) were evaluated at 0 (before application), 12, 19, 36, and 60 days after application (DAA). The time modified the technological attributes of sugarcane under ripener application. The highest apparent sucrose and total soluble solids values were obtained with NR+CR compared to the control. The NR and NR+CR treatments presented the highest TRS contents (150 kg Mg-1) at 36 DAA. Furthermore, the NR+CR treatment increased fiber content but did not compromise the quality of the raw material, and it showed high contents of SS and purity percentage, as well as low contents of RS. The chemical and nutritional ripeners efficiently promoted sugarcane ripening in areas without drying off before harvest. NR application at the end of the cycle can potentially increase sugar yield. fields sugarcanes s yield nutrients biostimulants acids Consequently agroindustrial agro industrial agents CR, CR , (CR) NR, (NR) NRCR replicates Agroindustrial Agro AS, AS (AS) RS, RS (RS) TRS, (TRS) (SS application, application) 12 19 6 DAA . (DAA) 150 (15 Mg1 Mg 1 Mg-1 3 Furthermore percentage harvest (CR (NR (AS (RS (TRS (DAA 15 (1 Mg- (
7.
Evaluation of Free- and Bound-Carbonyl Compounds in Craft Beers
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Carbonyl compounds (CC) can be formed during the craft beer production process, which influence the sensory properties, in addition to their toxicity. The formation of bound CC, in craft beers, is favored by the high reactivity of these substances. This work aimed to quantify 15 carbonyl compounds, in free and bound forms, in craft beers using hydrolysis (bound CC only) and derivatization reactions. Acetaldehyde concentrations ranged from 8.83 to 466.1 µg L-1 (free fraction) and 22.47 to 1665 µg L-1 (bound fraction). Other compounds found were acrolein (free + boundmax.: 2897 µg L-1), benzaldehyde (free + boundmax.: 1326 µg L-1), heptanal (free + boundmax.: 1140 µg L-1) and formaldehyde (free + boundmax.: 97.73 µg L-1). Craft beers showed a proportion of up to 76% for CC in the bound form, which can be related to undesirable flavors in beverages. The consumption of craft beers containing freeand bound-CC (especially acrolein) could pose a risk to the health of frequent consumers.
8.
Natural antioxidants: salinity atenuators and bio-stimulants antioxidants biostimulants bio stimulants
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Resumo A salinidade limita o crescimento e a produtividade das culturas, para reverter esses efeitos podem ser estudados pigmentos naturais com bioatividade antioxidante, como a cúrcuma (Curcuma longa L.) e a páprica (Capsicum annum L.). Portanto, objetivou-se avaliar a cúrcuma e a páprica como possíveis atenuadores do estresse salino e bioestimulantes durante a germinação e desenvolvimento inicial de plantas de alface lisa. No laboratório, as sementes foram tratadas por 1 hora com solução de páprica e cúrcuma nas doses 0 (controle negativo), 1, 2, 3 e 4 g L-1, e colocadas em substrato com solução salina de cloreto de sódio 4 g L-1 (-0,4 Mpa) e um controle positivo, composta por sementes secas dispostas em substrato umedecido com água destilada. Foram realizados análises de qualidade fisiológica e para a dose que apresentou melhor resultado (4 g L-1) as sementes tratadas foram cultivadas em casa de vegetação e receberam aplicações semanais via foliar com solução 4 g L-1 de cúrcuma e páprica. Após o ciclo da cultura foram realizadas análises morfométricas. As soluções de cúrcuma e páprica foram analisadas por Cromatografia Líquida de Alta Eficiência (CLAE) para identificação da presença das substâncias bioativas. As doses de cúrcuma não foram eficientes em superar os efeitos da salinidade nas sementes e mudas, o que foi atribuído à baixa solubilidade da cúrcuma em água. A páprica, embora não tenha proporcionado o efeito bioestimulante, foi eficiente em atenuar os efeitos do excesso de sal, na concentração de 4 g L- 1, promovendo aumentos na qualidade fisiológica. Na CLAE foi observado um sinal de resposta muito baixo em relação às amostras compostas por soluções de cúrcuma e páprica, indicando um baixo percentual de compostos solúveis, o que compromete a bioatividade, e leva à necessidade de novas análises com o uso de surfactantes e/ou de outros solventes com os quais haja maior afinidade. culturas antioxidante Curcuma L. L Capsicum L.. . Portanto objetivouse objetivou se lisa laboratório negativo, negativo , negativo) 2 L1, L1 0,4 04 (-0, Mpa positivo destilada ( morfométricas (CLAE bioativas mudas bioestimulante sal solúveis eou ou afinidade 0, (-0 (-
Abstract Salinity limits the growth and productivity of crops, to reverse these effects, natural pigments with antioxidant bioactivity can be studied, such as turmeric (Curcuma longa L.) and paprika (Capsicum annum L.). Therefore, it aimed to evaluate turmeric and paprika as possible saline stress attenuators and biostimulants during germination and initial development of smooth lettuce seedlings. In the laboratory, the seeds were treated for 1 hour with a solution of paprika and turmeric at doses 0 (negative control), 1, 2, 3 and 4 g L-1, and placed on a substrate with saline solution of sodium chloride 4 g L-1 (-0,4 Mpa), and a positive control, composed of dry seeds arranged in a substrate moistened with distilled water. Physiological quality analysis were carried out, and for the dose that showed the best result (4 g L-1), the treated seeds were grown in a greenhouse, and received weekly applications via foliar with a 4 g L-1 solution for turmeric and paprika. After the crop cycle, morphometric analyzes were performed. The turmeric and paprika solutions were analyzed by High-Performance Liquid Chromatography (HPLC) to identify the presence of bioactive substances. The turmeric doses were not efficient in overcoming the effects of salinity on seeds and seedlings, which was attributed to the low solubility of turmeric in water. Paprika, although it did not provide the biostimulant effect, was efficient in attenuating the effects of excess salt, at a concentration of 4 g L-1, promoting increases in physiological quality. In HPLC, a very low signal response was noted in relation to samples composed of turmeric and paprika solutions, indicating a low percentage of soluble compounds, which compromises bioactivity, and leads to the need for further analyses using surfactants and/or other solvents with which there is greater affinity. crops studied Curcuma L. L Capsicum L.. . Therefore seedlings laboratory negative control , control) 2 L1, L1 L- 0,4 04 (-0, Mpa, Mpa Mpa) water out ( L-1) greenhouse cycle performed HighPerformance High Performance HPLC (HPLC substances Paprika effect salt compounds andor or affinity 0, (-0 (-
9.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
Slipinski, Adam
Linzmeier, Adelita M.
Calor, Adolfo R.
Garda, Adrian A.
Kury, Adriano B.
Fernandes, Agatha C.S.
Agudo-Padrón, Aisur I.
Akama, Alberto
Silva Neto, Alberto M. da
Burbano, Alejandro L.
Menezes, Aleksandra
Pereira-Colavite, Alessandre
Anichtchenko, Alexander
Lees, Alexander C.
Bezerra, Alexandra M.R.
Domahovski, Alexandre C.
Pimenta, Alexandre D.
Aleixo, Alexandre L.P.
Marceniuk, Alexandre P.
Paula, Alexandre S. de
Somavilla, Alexandre
Specht, Alexandre
Camargo, Alexssandro
Newton, Alfred F.
Silva, Aline A.S. da
Santos, Aline B. dos
Tassi, Aline D.
Aragão, Allan C.
Santos, Allan P.M.
Migotto, Alvaro E.
Mendes, Amanda C.
Cunha, Amanda
Chagas Júnior, Amazonas
Sousa, Ana A.T. de
Pavan, Ana C.
Almeida, Ana C.S.
Peronti, Ana L.B.G.
Henriques-Oliveira, Ana L.
Prudente, Ana L.
Tourinho, Ana L.
Pes, Ana M.O.
Carmignotto, Ana P.
Wengrat, Ana P.G. da Silva
Dornellas, Ana P.S.
Molin, Anamaria Dal
Puker, Anderson
Morandini, André C.
Ferreira, André da S.
Martins, André L.
Esteves, André M.
Fernandes, André S.
Roza, André S.
Köhler, Andreas
Paladini, Andressa
Andrade, Andrey J. de
Pinto, Ângelo P.
Salles, Anna C. de A.
Gondim, Anne I.
Amaral, Antonia C.Z.
Rondón, Antonio A.A.
Brescovit, Antonio
Lofego, Antônio C.
Marques, Antonio C.
Macedo, Antonio
Andriolo, Artur
Henriques, Augusto L.
Ferreira Júnior, Augusto L.
Lima, Aurino F. de
Barros, Ávyla R. de A.
Brito, Ayrton do R.
Romera, Bárbara L.V.
Vasconcelos, Beatriz M.C. de
Frable, Benjamin W.
Santos, Bernardo F.
Ferraz, Bernardo R.
Rosa, Brunno B.
Sampaio, Brunno H.L.
Bellini, Bruno C.
Clarkson, Bruno
Oliveira, Bruno G. de
Corrêa, Caio C.D.
Martins, Caleb C.
Castro-Guedes, Camila F. de
Souto, Camilla
Bicho, Carla de L.
Cunha, Carlo M.
Barboza, Carlos A. de M.
Lucena, Carlos A.S. de
Barreto, Carlos
Santana, Carlos D.C.M. de
Agne, Carlos E.Q.
Mielke, Carlos G.C.
Caetano, Carlos H.S.
Flechtmann, Carlos H.W.
Lamas, Carlos J.E.
Rocha, Carlos
Mascarenhas, Carolina S.
Margaría, Cecilia B.
Waichert, Cecilia
Digiani, Celina
Haddad, Célio F.B.
Azevedo, Celso O.
Benetti, Cesar J.
Santos, Charles M.D. dos
Bartlett, Charles R.
Bonvicino, Cibele
Ribeiro-Costa, Cibele S.
Santos, Cinthya S.G.
Justino, Cíntia E.L.
Canedo, Clarissa
Bonecker, Claudia C.
Santos, Cláudia P.
Carvalho, Claudio J.B. de
Gonçalves, Clayton C.
Galvão, Cleber
Costa, Cleide
Oliveira, Cléo D.C. de
Schwertner, Cristiano F.
Andrade, Cristiano L.
Pereira, Cristiano M.
Sampaio, Cristiano
Dias, Cristina de O.
Lucena, Daercio A. de A.
Manfio, Daiara
Amorim, Dalton de S.
Queiroz, Dalva L. de
Queiroz, Dalva L. de
Colpani, Daniara
Abbate, Daniel
Aquino, Daniel A.
Burckhardt, Daniel
Cavallari, Daniel C.
Prado, Daniel de C. Schelesky
Praciano, Daniel L.
Basílio, Daniel S.
Bená, Daniela de C.
Toledo, Daniela G.P. de
Takiya, Daniela M.
Fernandes, Daniell R.R.
Ament, Danilo C.
Cordeiro, Danilo P.
Silva, Darliane E.
Pollock, Darren A.
Muniz, David B.
Gibson, David I.
Nogueira, David S.
Marques, Dayse W.A.
Lucatelli, Débora
Garcia, Deivys M.A.
Baêta, Délio
Ferreira, Denise N.M.
Rueda-Ramírez, Diana
Fachin, Diego A.
Souza, Diego de S.
Rodrigues, Diego F.
Pádua, Diego G. de
Barbosa, Diego N.
Dolibaina, Diego R.
Amaral, Diogo C.
Chandler, Donald S.
Maccagnan, Douglas H.B.
Caron, Edilson
Carvalho, Edrielly
Adriano, Edson A.
Abreu Júnior, Edson F. de
Pereira, Edson H.L.
Viegas, Eduarda F.G.
Carneiro, Eduardo
Colley, Eduardo
Eizirik, Eduardo
Santos, Eduardo F. dos
Shimbori, Eduardo M.
Suárez-Morales, Eduardo
Arruda, Eliane P. de
Chiquito, Elisandra A.
Lima, Élison F.B.
Castro, Elizeu B. de
Orlandin, Elton
Nascimento, Elynton A. do
Razzolini, Emanuel
Gama, Emanuel R.R.
Araujo, Enilma M. de
Nishiyama, Eric Y.
Spiessberger, Erich L.
Santos, Érika C.L. dos
Contreras, Eugenia F.
Galati, Eunice A.B.
Oliveira Junior, Evaldo C. de
Gallardo, Fabiana
Hernandes, Fabio A.
Lansac-Tôha, Fábio A.
Pitombo, Fabio B.
Dario, Fabio Di
Santos, Fábio L. dos
Mauro, Fabio
Nascimento, Fabio O. do
Olmos, Fabio
Amaral, Fabio R.
Schunck, Fabio
Godoi, Fábio S. P. de
Machado, Fabrizio M.
Barbo, Fausto E.
Agrain, Federico A.
Ribeiro, Felipe B.
Moreira, Felipe F.F.
Barbosa, Felipe F.
Silva, Fenanda S.
Cavalcanti, Fernanda F.
Straube, Fernando C.
Carbayo, Fernando
Carvalho Filho, Fernando
Zanella, Fernando C.V.
Jacinavicius, Fernando de C.
Farache, Fernando H.A.
Leivas, Fernando
Dias, Fernando M.S.
Mantellato, Fernando
Vaz-de-Mello, Fernando Z.
Gudin, Filipe M.
Albuquerque, Flávio
Molina, Flavio B.
Passos, Flávio D.
Shockley, Floyd W.
Pinheiro, Francielly F.
Mello, Francisco de A.G. de
Nascimento, Francisco E. de L.
Franco, Francisco L.
Oliveira, Francisco L. de
Melo, Francisco T. de V.
Quijano, Freddy R.B.
Salles, Frederico F.
Biffi, Gabriel
Queiroz, Gabriel C.
Bizarro, Gabriel L.
Hrycyna, Gabriela
Leviski, Gabriela
Powell, Gareth S.
Santos, Geane B. dos
Morse, Geoffrey E.
Brown, George
Mattox, George M.T.
Zimbrão, Geraldo
Carvalho, Gervásio S.
Miranda, Gil F.G.
Moraes, Gilberto J. de
Lourido, Gilcélia M.
Neves, Gilmar P.
Moreira, Gilson R.P.
Montingelli, Giovanna G.
Maurício, Giovanni N.
Marconato, Gláucia
Lopez, Guilherme E.L.
Silva, Guilherme L. da
Muricy, Guilherme
Brito, Guilherme R.R.
Garbino, Guilherme S.T.
Flores, Gustavo E.
Graciolli, Gustavo
Libardi, Gustavo S.
Proctor, Heather C.
Gil-Santana, Helcio R.
Varella, Henrique R.
Escalona, Hermes E.
Schmitz, Hermes J.
Rodrigues, Higor D.D.
Galvão Filho, Hilton de C.
Quintino, Hingrid Y.S.
Pinto, Hudson A.
Rainho, Hugo L.
Miyahira, Igor C.
Gonçalves, Igor de S.
Martins, Inês X.
Cardoso, Irene A.
Oliveira, Ismael B. de
Franz, Ismael
Fernandes, Itanna O.
Golfetti, Ivan F.
S. Campos-Filho, Ivanklin
Oliveira, Ivo de S.
Delabie, Jacques H.C.
Oliveira, Jader de
Prando, Jadila S.
Patton, James L.
Bitencourt, Jamille de A.
Silva, Janaina M.
Santos, Jandir C.
Arruda, Janine O.
Valderrama, Jefferson S.
Dalapicolla, Jeronymo
Oliveira, Jéssica P.
Hájek, Jiri
Morselli, João P.
Narita, João P.
Martin, João P.I.
Grazia, Jocélia
McHugh, Joe
Cherem, Jorge J.
Farias Júnior, José A.S.
Fernandes, Jose A.M.
Pacheco, José F.
Birindelli, José L.O.
Rezende, José M.
Avendaño, Jose M.
Duarte, José M. Barbanti
Ribeiro, José R. Inácio
Mermudes, José R.M.
Pujol-Luz, José R.
Santos, Josenilson R. dos
Câmara, Josenir T.
Teixeira, Joyce A.
Prado, Joyce R. do
Botero, Juan P.
Almeida, Julia C.
Kohler, Julia
Gonçalves, Julia P.
Beneti, Julia S.
Donahue, Julian P.
Alvim, Juliana
Almeida, Juliana C.
Segadilha, Juliana L.
Wingert, Juliana M.
Barbosa, Julianna F.
Ferrer, Juliano
Santos, Juliano F. dos
Kuabara, Kamila M.D.
Nascimento, Karine B.
Schoeninger, Karine
Campião, Karla M.
Soares, Karla
Zilch, Kássia
Barão, Kim R.
Teixeira, Larissa
Sousa, Laura D. do N.M. de
Dumas, Leandro L.
Vieira, Leandro M.
Azevedo, Leonardo H.G.
Carvalho, Leonardo S.
Souza, Leonardo S. de
Rocha, Leonardo S.G.
Bernardi, Leopoldo F.O.
Vieira, Letícia M.
Johann, Liana
Salvatierra, Lidianne
Oliveira, Livia de M.
Loureiro, Lourdes M.A. El-moor
Barreto, Luana B.
Barros, Luana M.
Lecci, Lucas
Camargos, Lucas M. de
Lima, Lucas R.C.
Almeida, Lucia M.
Martins, Luciana R.
Marinoni, Luciane
Moura, Luciano de A.
Lima, Luciano
Naka, Luciano N.
Miranda, Lucília S.
Salik, Lucy M.
Bezerra, Luis E.A.
Silveira, Luis F.
Campos, Luiz A.
Castro, Luiz A.S. de
Pinho, Luiz C.
Silveira, Luiz F.L.
Iniesta, Luiz F.M.
Tencatt, Luiz F.C.
Simone, Luiz R.L.
Malabarba, Luiz R.
Cruz, Luiza S. da
Sekerka, Lukas
Barros, Lurdiana D.
Santos, Luziany Q.
Skoracki, Maciej
Correia, Maira A.
Uchoa, Manoel A.
Andrade, Manuella F.G.
Hermes, Marcel G.
Miranda, Marcel S.
Araújo, Marcel S. de
Monné, Marcela L.
Labruna, Marcelo B.
Santis, Marcelo D. de
Duarte, Marcelo
Knoff, Marcelo
Nogueira, Marcelo
Britto, Marcelo R. de
Melo, Marcelo R.S. de
Carvalho, Marcelo R. de
Tavares, Marcelo T.
Kitahara, Marcelo V.
Justo, Marcia C.N.
Botelho, Marcia J.C.
Couri, Márcia S.
Borges-Martins, Márcio
Felix, Márcio
Oliveira, Marcio L. de
Bologna, Marco A.
Gottschalk, Marco S.
Tavares, Marcos D.S.
Lhano, Marcos G.
Bevilaqua, Marcus
Santos, Marcus T.T.
Domingues, Marcus V.
Sallum, Maria A.M.
Digiani, María C.
Santarém, Maria C.A.
Nascimento, Maria C. do
Becerril, María de los A.M.
Santos, Maria E.A. dos
Passos, Maria I. da S. dos
Felippe-Bauer, Maria L.
Cherman, Mariana A.
Terossi, Mariana
Bartz, Marie L.C.
Barbosa, Marina F. de C.
Loeb, Marina V.
Cohn-Haft, Mario
Cupello, Mario
Martins, Marlúcia B.
Christofersen, Martin L.
Bento, Matheus
Rocha, Matheus dos S.
Martins, Maurício L.
Segura, Melissa O.
Cardenas, Melissa Q.
Duarte, Mércia E.
Ivie, Michael A.
Mincarone, Michael M.
Borges, Michela
Monné, Miguel A.
Casagrande, Mirna M.
Fernandez, Monica A.
Piovesan, Mônica
Menezes, Naércio A.
Benaim, Natalia P.
Reategui, Natália S.
Pedro, Natan C.
Pecly, Nathalia H.
Ferreira Júnior, Nelson
Silva Júnior, Nelson J. da
Perioto, Nelson W.
Hamada, Neusa
Degallier, Nicolas
Chao, Ning L.
Ferla, Noeli J.
Mielke, Olaf H.H.
Evangelista, Olivia
Shibatta, Oscar A.
Oliveira, Otto M.P.
Albornoz, Pablo C.L.
Dellapé, Pablo M.
Gonçalves, Pablo R.
Shimabukuro, Paloma H.F.
Grossi, Paschoal
Rodrigues, Patrícia E. da S.
Lima, Patricia O.V.
Velazco, Paul
Santos, Paula B. dos
Araújo, Paula B.
Silva, Paula K.R.
Riccardi, Paula R.
Garcia, Paulo C. de A.
Passos, Paulo G.H.
Corgosinho, Paulo H.C.
Lucinda, Paulo
Costa, Paulo M.S.
Alves, Paulo P.
Roth, Paulo R. de O.
Coelho, Paulo R.S.
Duarte, Paulo R.M.
Carvalho, Pedro F. de
Gnaspini, Pedro
Souza-Dias, Pedro G.B.
Linardi, Pedro M.
Bartholomay, Pedro R.
Demite, Peterson R.
Bulirsch, Petr
Boll, Piter K.
Pereira, Rachel M.M.
Silva, Rafael A.P.F.
Moura, Rafael B. de
Boldrini, Rafael
Silva, Rafaela A. da
Falaschi, Rafaela L.
Cordeiro, Ralf T.S.
Mello, Ramon J.C.L.
Singer, Randal A.
Querino, Ranyse B.
Heleodoro, Raphael A.
Castilho, Raphael de C.
Constantino, Reginaldo
Guedes, Reinaldo C.
Carrenho, Renan
Gomes, Renata S.
Gregorin, Renato
Machado, Renato J.P.
Bérnils, Renato S.
Capellari, Renato S.
Silva, Ricardo B.
Kawada, Ricardo
Dias, Ricardo M.
Siewert, Ricardo
Brugnera, Ricaro
Leschen, Richard A.B.
Constantin, Robert
Robbins, Robert
Pinto, Roberta R.
Reis, Roberto E. dos
Ramos, Robson T. da C.
Cavichioli, Rodney R.
Barros, Rodolfo C. de
Caires, Rodrigo A.
Salvador, Rodrigo B.
Marques, Rodrigo C.
Araújo, Rodrigo C.
Araujo, Rodrigo de O.
Dios, Rodrigo de V.P.
Johnsson, Rodrigo
Feitosa, Rodrigo M.
Hutchings, Roger W.
Lara, Rogéria I.R.
Rossi, Rogério V.
Gerstmeier, Roland
Ochoa, Ronald
Hutchings, Rosa S.G.
Ale-Rocha, Rosaly
Rocha, Rosana M. da
Tidon, Rosana
Brito, Rosangela
Pellens, Roseli
Santos, Sabrina R. dos
Santos, Sandra D. dos
Paiva, Sandra V.
Santos, Sandro
Oliveira, Sarah S. de
Costa, Sávio C.
Gardner, Scott L.
Leal, Sebastián A. Muñoz
Aloquio, Sergio
Bonecker, Sergio L.C.
Bueno, Sergio L. de S.
Almeida, Sérgio M. de
Stampar, Sérgio N.
Andena, Sérgio R.
Posso, Sergio R.
Lima, Sheila P.
Gadelha, Sian de S.
Thiengo, Silvana C.
Cohen, Simone C.
Brandão, Simone N.
Rosa, Simone P.
Ribeiro, Síria L.B.
Letana, Sócrates D.
Santos, Sonia B. dos
Andrade, Sonia C.S.
Dávila, Stephane
Vaz, Stéphanie
Peck, Stewart B.
Christo, Susete W.
Cunha, Suzan B.Z.
Gomes, Suzete R.
Duarte, Tácio
Madeira-Ott, Taís
Marques, Taísa
Roell, Talita
Lima, Tarcilla C. de
Sepulveda, Tatiana A.
Maria, Tatiana F.
Ruschel, Tatiana P.
Rodrigues, Thaiana
Marinho, Thais A.
Almeida, Thaís M. de
Miranda, Thaís P.
Freitas, Thales R.O.
Pereira, Thalles P.L.
Zacca, Thamara
Pacheco, Thaynara L.
Martins, Thiago F.
Alvarenga, Thiago M.
Carvalho, Thiago R. de
Polizei, Thiago T.S.
McElrath, Thomas C.
Henry, Thomas
Pikart, Tiago G.
Porto, Tiago J.
Krolow, Tiago K.
Carvalho, Tiago P.
Lotufo, Tito M. da C.
Caramaschi, Ulisses
Pinheiro, Ulisses dos S.
Pardiñas, Ulyses F.J.
Maia, Valéria C.
Tavares, Valeria
Costa, Valmir A.
Amaral, Vanessa S. do
Silva, Vera C.
Wolff, Vera R. dos S.
Slobodian, Verônica
Silva, Vinícius B. da
Espíndola, Vinicius C.
Costa-Silva, Vinicius da
Bertaco, Vinicius de A.
Padula, Vinícius
Ferreira, Vinicius S.
Silva, Vitor C.P. da
Piacentini, Vítor de Q.
Sandoval-Gómez, Vivian E.
Trevine, Vivian
Sousa, Viviane R.
Sant’Anna, Vivianne B. de
Mathis, Wayne N.
Souza, Wesley de O.
Colombo, Wesley D.
Tomaszewska, Wioletta
Wosiacki, Wolmar B.
Ovando, Ximena M.C.
Leite, Yuri L.R.








ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
10.
Ora-pro-nobis (Pereskia aculeata) supplementation promotes increased longevity associated with improved antioxidant status in Drosophila melanogaster Orapronobis Ora pro nobis Pereskia aculeata
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SANTOS, AMANDA M. DOS
; MUSACHIO, ELIZE
; ANDRADE, STEFANI S.
; JANNER, DIENIFFER E.
; MEICHTRY, LUANA B.
; LIMA, KATTIELE F.
; FERNANDES, ELIANA J.
; PRIGOL, MARINA
; KAMINSKI, TIAGO ANDRÉ
.









Abstract This study evaluated the effects of ora-pro-nobis (Pereskia aculeate) flour supplementation on the in vivo basal antioxidant system of Drosophila melanogaster, and its action on the neural modulation observed by the enzyme acetylcholinesterase (AChE). The flies will receive a standard diet with flour incorporated at 5, 10 and 20% for 7 days. There was no change in food consumption, body weight, protein thiol levels and negative geotaxis behavior. The flies showed a reduction in the basal production of reactive species at concentrations of 10 and 20%, while there was a reduction in lipid peroxidation and catalase activity at all concentrations, accompanied by an increase in the levels of non-protein thiols. Superoxide dismutase activity was reduced in the 5 and 20% groups, while the reduction of superoxide anion in the 10% group may have contributed to the increase in longevity also in the 10% group. Longevity increased in groups 5 and 10%. The open field test may be related to the reduction in AChE activity in the 5, 10 and 20% groups. In general, the data show that supplementation with ora-pro-nobis flour at the concentrations tested did not cause toxicity and modulated the cholinergic system, demonstrating a therapeutic potential. orapronobis ora pro nobis Pereskia aculeate melanogaster AChE. . (AChE) 1 20 days consumption weight behavior nonprotein non thiols general potential (AChE 2
11.
Two new species of Neoplecostomus (Siluriformes: Loricariidae) from high altitudes of the upper rio Paraná basin, Brazil Siluriformes (Siluriformes Loricariidae basin
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Uzeda, Pedro L. C.
; Paiola, Isabel
; Cesar, Poliana S.
; Okubo, Vitor Kenzo N.
; Marques-Frisoni, Wellington J.
; Andrade, Breno N.
; Langeani, Francisco
.







Resumo Duas novas espécies de Neoplecostomus são descritas de cabeceiras da drenagem do rio Sapucaí, afluente do rio Grande no alto rio Paraná. As novas espécies são as mais similares entre si, e podem ser diagnosticadas das demais congêneres por terem a área exposta das primeiras placas das séries médio-ventral e ventral mais estreitas que as áreas nuas circundando cada placa; dentes com morfologias e quantidades diferentes em machos e fêmeas; arranjo dos odontódeos nas placas do pedúnculo caudal; tamanho da nadadeira adiposa e caracteres osteológicos craniais. Ambas são endêmicas da Serra da Mantiqueira, no sudeste brasileiro. Alguns comentários são feitos sobre suas variações intraespecíficas, genética e conservação. Sapucaí Paraná si médioventral médio placa fêmeas caudal craniais Mantiqueira brasileiro intraespecíficas conservação
Abstract Two new species of Neoplecostomus are described from the headwaters of the rio Sapucaí drainage, affluent of the rio Grande in upper rio Paraná basin. The new species are most similar to each other, and can be diagnosed from congeners by having the exposed area of the first plates of mid-ventral and ventral series narrower than the naked area surrounding each plate; different tooth morphologies and numbers in males and females; arrangement of odontodes on caudal-peduncle plates; size of adipose fin and cranial osteological character states. Both new species are endemic to Serra da Mantiqueira, southeastern Brazil. Some comments are made on their intraspecific variation, genetics, and conservation. drainage basin other midventral mid plate females caudalpeduncle caudal peduncle states Mantiqueira Brazil variation genetics conservation
12.
Coleoptera of Brazil: what we knew then and what we know now. Insights from the Catálogo Taxonômico da Fauna do Brasil Brazil now
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Caron, Edilson
; Monné, Marcela L.
; Ferreira, Vinicius S.
; Costa, Cleide
; Cupello, Mario
; Aloquio, Sergio
; Linzmeier, Adelita M.
; Vaz-de-Mello, Fernando Z.
; Leivas, Fernando W.T.
; Souza-Gonçalves, Igor
; Mermudes, José R.M.
; Almeida, Lúcia M.
; Moura, Luciano de A.
; Ferreira Júnior, Nelson
; Grossi, Paschoal C.
; Vanin, Sergio A.
; Ślipiński, Adam
; Anichtchenko, Alexander
; Newton, Alfred F.
; Sampaio, Aline
; Carelli, Allan
; Puker, Anderson
; Ferreira, André da S.
; Fernandes, André S.
; Roza, André S.
; Cline, Andrew
; Sampaio, Brunno H.L.
; Clarkson, Bruno
; Castro, Camila F. de
; Bicho, Carla de L.
; Benetti, César J.
; Ribeiro-Costa, Cibele S.
; Lopes-Andrade, Cristiano
; Manfio, Daiara
; Colpani, Daniara
; Basílio, Daniel S.
; Bená, Daniela de C.
; Pollock, Darren A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Chandler, Donald S.
; Nascimento, Elynton A. do
; Spiessberger, Erich L.
; Agrain, Federico A.
; Barbosa, Felipe F.
; Shockley, Floyd
; Nascimento, Francisco E. de L.
; Biffi, Gabriel
; Powell, Gareth S.
; Morse, Geoffrey E.
; Flores, Gustavo E.
; Escalona, Hermes
; Quintino, Hingrid Y.S.
; Rainho, Hugo L.
; Maddalena, Italo S.C.P.
; Hájek, Jiří
; McHugh, Joseph V.
; Botero, Juan P.
; Fuhrmann, Juares
; Churata-Salcedo, Julissa M.
; Vieira, Letícia M.
; Silveira, Luiz F.L. da
; Cruz, Luiza S. da
; Sekerka, Lukás
; Bologna, Marco A.
; Bevilaqua, Marcus V.O.
; Passos, Maria I.
; Chamorro, Maria L.
; Cherman, Mariana A.
; Bento, Matheus
; Gimmel, Matthew
; Segura, Melissa O.
; Ivie, Michael A.
; Thomas, Michael C.
; Monné, Miguel A.
; Lord, Nathan
; Hamada, Neusa
; Degallier, Nicolas
; Santos, Paula B. dos
; Duarte, Paulo R.M.
; Gnaspini, Pedro
; Bulirsch, Petr
; Regalin, Renato
; Leschen, Richard A.B.
; Constantin, Robert
; Corrêa, Rodrigo C.
; Gerstmeier, Roland
; Rosa, Simone P.
; Campos, Stéphanie V.N.
; Peck, Stewart B.
; Pacheco, Thaynara L.
; Polizei, Thiago T.S.
; McElrath, Thomas C.
; Grzymala, Traci L.
; Smith, Trevor R.
; Costa-Silva, Vinicius da
Sandoval-Gómez, Vivian E.
Sousa, Wesley O. de
Tomaszewska, Wioletta































































































ABSTRACT In 2000, Cleide Costa published a paper presenting the state of knowledge of the Neotropical Coleopte ra, with a focus on the Brazilian fauna. Twenty-four years later, thanks to the development of the Coleoptera section of the Taxonomic Catalog of the Brazilian Fauna (CTFB - Catálogo Taxonômico da Fauna do Brasil) through the collaboration of 100 coleopterists from all over the globe, we can build on Costa’s work and present an updated overview of the state of knowledge of the beetles from Brazil. There are currently 35,699 species in 4,958 genera and 116 families known to occur in the country, including representatives of all extant suborders and superfamilies. Our data show that the Brazilian beetle fauna is the richest on the planet, concentrating 9% of the world species diversity, with some estimates accounting to up to 15% of the global total. The most diverse family in numbers of genera is Cerambycidae (1,056 genera), while in number of species it is Chrysomelidae (6,079 species). Conotrachelus Dejean, 1835 (Curculionidae) is the most species-rich genus, with 570 species. The French entomologist Maurice Pic is the author who has contributed the most to the naming of species recorded from Brazil, with 1,794 valid names in 36 families, whereas the Brazilians Ubirajara R. Martins and Maria Helena M. Galileo are the only ones among the top-ten authors to have named species in the 21st century. Currently, approximately 144 new species of Brazilian beetles are described each year, and this average is projected to increase in the next decade to 180 species per year, or about one new Brazilian beetle every two days. 2000 ra Twentyfour Twenty four later CTFB Brasil 10 globe Costas s Brazil 35699 35 699 35,69 4958 4 958 4,95 11 country superfamilies planet 9 diversity 15 total 1,056 1056 1 056 (1,05 genera, , genera) 6,079 6079 6 079 (6,07 . species) Dejean 183 Curculionidae (Curculionidae speciesrich rich genus 57 1794 794 1,79 3 R M topten top ten st century Currently 14 year 18 days 200 3569 69 35,6 495 95 4,9 1,05 105 05 (1,0 6,07 607 07 (6,0 5 179 79 1,7 20 356 35, 49 4, 1,0 0 (1, 6,0 60 (6, 17 7 1, 2 (1 6, (6 (
13.
The physiological quality of Vigna unguiculata L. seeds shows tolerance to salinity L
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Andrade, F. H. A.
; Silva, R. T.
; Barbosa Neto, M. A.
; Silva, S. F.
; Cardoso, A. F. L.
; Lima, J. S.
; Silva, J. H. B.
; Cruz, A. F. S.
; Clemente, M. I. B.
; Onias, E. A.
; Pereira, W. E.
; Chaves, J. T. L.
; Borges, S. G. S.
; Oliveira, A. M. F.
; Linhares, P. C. A.
; Silva, R. R.
.
















Resumo A salinidade reduz a produção de feijão-caupi, e a busca por variedades tolerantes torna-se importante dentro do contexto agrícola, pois, além de serem utilizadas no campo, podem utilizar-se no melhoramento genético. Com isso, objetivou-se buscar alguma variedade crioula que seja tolerante à salinidade considerando a qualidade fisiológica de sementes e crescimento da plântula. Utilizou-se um esquema fatorial 2 × 4, correspondendo às variedades Pingo-de-ouro e Coruja, e quatro condutividades elétricas da água de irrigação (0; 3,3; 6,6 e 9,9 dS m-1). Analisou-se a qualidade fisiológica de sementes e o crescimento das plântulas, além da germinação cumulativa. A variedade Pingo-de-ouro, não apresentou germinação, comprimento da parte aérea e raiz, massa seca da parte aérea e raiz comprometida até condutividade elétrica de 6 dS m-1 em relação a 0,0 dS m-1. Por outro lado, a variedade Coruja apresentou redução da germinação, aumento no comprimento da parte aérea e raiz. A variedade crioula Pingo-de-ouro se mostrou tolerante à salinidade. feijãocaupi, feijãocaupi feijão caupi, caupi feijão-caupi tornase torna agrícola pois campo utilizarse utilizar genético isso objetivouse objetivou plântula Utilizouse Utilizou 4 Pingodeouro Pingo ouro 0 (0 3,3 33 3 66 6, 99 9 9, m1. m1 m 1 . m-1) Analisouse Analisou plântulas cumulativa Pingodeouro, ouro, m- 00 0, 1. lado ( 3,
Abstract Salinity reduces feijão-caupi production, and the search for tolerant varieties becomes important within the agricultural context, as, in addition to being used in the field, they can be used in genetic improvement. The objective was to for a identify variety that is tolerant to salinity considering the physiological quality of seeds and seedling growth. A 2 × 4 factorial scheme was used, referring to the varieties Pingo-de-ouro and Coruja, and four electrical conductivities of water (0; 3.3; 6.6 and 9.9 dS m-1). The physiological quality of seeds and the growth of seedlings were analyzed, in addition to the cumulative germination. The Pingo-de-ouro variety showed no germination, length of the shoot and root, dry mass of the shoot and root compromised up to electrical conductivity of 6 dS m-1 in relation to 0.0 dS m-1. On the other hand, the Coruja variety showed reduced germination, increased shoot and root length. The creole variety Pingo-de-ouro proved to be tolerant to salinity. feijãocaupi feijão caupi production context as field improvement Pingodeouro Pingo de ouro 0 (0 3.3 33 3 66 6. 99 9 9. m1. m1 m 1 . m-1) analyzed germination m- 00 0. 1. hand ( 3.
14.
Calibration and evaluation of CSM-CROPGRO-soybean for soybean crop in the southwestern cerrado of Piauí CSMCROPGROsoybean CSM CROPGRO
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Irene Filho, João
; Andrade Júnior, Aderson S. de
; Cuadra, Santiago V.
; Silva, Everaldo M. da
; Vieira, Paulo F. de M. J.
.





RESUMO Objetivou-se, calibrar e avaliar o modelo DSSAT CSM-CROPGRO-Soybean na simulação do rendimento de grãos de soja na região do cerrado do Sudoeste Piauiense. Para a parametrização do modelo, foram utilizados dados do ano agrícola 2019-2020, de um experimento instalado na Serra do Quilombo, no município de Bom Jesus-PI (9º16'20,3'' S, 44º44'56,9'' O e altitude 620 m). Foram avaliadas as cultivares BRS 8980 IPRO (BRS 8980), BMX 84I86 (Domínio), BMX 81I81RSF IPRO (Extrema) e BMX 8579 IPRO (Bônus), em três datas de semeadura (29/11/2019, 14/01/2020 e 30/01/2020). A avaliação foi realizada com dados de rendimento de grãos de soja coletados em ensaios de valor de cultivo e uso (VCU) conduzido pela Embrapa Meio-Norte, na Fazenda Celeiro, Serra do Quilombo, Bom Jesus, PI, durante quatro safras e envolvendo 61 genótipos. Os melhores índices estatísticos que evidenciam a eficiência do processo de calibração foram observados para as cultivares BRS 8980 (1ª época de semeadura) e Bônus (3ª época de semeadura), com índices R2 e D superiores a 0,90. A produção de biomassa total apresentou alta concordância com os valores medidos, capturando bem o decréscimo da produção em fundação da data de semeadura. O modelo capturou bem a variabilidade em função das datas de plantio, assim como o rendimento para simulações de outras quatro safras agrícolas, independentes da safra onde o modelo foi calibrado. Concluiu-se que o modelo simulou satisfatoriamente o crescimento das plantas e o rendimento de grãos de soja para as condições da região do cerrado do Sudoeste Piauiense. Objetivouse, Objetivouse Objetivou se, se Objetivou-se CSMCROPGROSoybean CSM CROPGRO Soybean Piauiense 20192020, 20192020 2019 2020, 2020 2019-2020 Quilombo JesusPI Jesus PI 9º1620,3 9º16203 º 9º16 20,3 20 3 (9º16'20,3' S 44º4456,9 44º44569 44º44 56,9 56 9 44º44'56,9' 62 m. m . m) 898 8980, , 8980) I 84I8 Domínio, Domínio (Domínio) IRSF RSF Extrema (Extrema 857 Bônus, (Bônus) 29/11/2019, 29112019 29 11 (29/11/2019 14012020 14 01 14/01/202 30/01/2020. 30012020 30/01/2020 30 30/01/2020) VCU (VCU MeioNorte, MeioNorte Meio Norte, Norte Meio-Norte Celeiro 6 genótipos 1ª ª 3ª semeadura, R 090 0 90 0,90 medidos plantio agrícolas calibrado Concluiuse Concluiu 2019202 201 202 2019-202 9º1620 9º1620, 9º1 203 20, 2 (9º16'20,3 44º4456 44º4456, 44º4 569 56, 5 44º44'56,9 89 84I (Domínio 85 (Bônus 29/11/2019 2911201 1 (29/11/201 1401202 14/01/20 3001202 30/01/202 09 0,9 201920 2019-20 9º162 9º (9º16'20, 44º445 44º 44º44'56, 8 29/11/201 291120 (29/11/20 140120 14/01/2 300120 30/01/20 0, 20192 2019-2 (9º16'20 44º44'56 29/11/20 29112 (29/11/2 14012 14/01/ 30012 30/01/2 2019- (9º16'2 44º44'5 29/11/2 2911 (29/11/ 1401 14/01 3001 30/01/ (9º16' 44º44' 29/11/ 291 (29/11 140 14/0 300 30/01 (9º16 29/11 (29/1 14/ 30/0 (9º1 29/1 (29/ 30/ (9º 29/ (29 (2 (
ABSTRACT The study aimed to calibrate and evaluate the DSSAT CSM-CROPGRO-Soybean model to simulate soybean grain yields in the Cerrado of the Southwestern region of Piaui. To parameterize the model, data from the 2019-2020 crop season was used from an experiment installed in the Serra do Quilombo, in Bom Jesus-PI (9º16'20.3'' S, 44º44'56.9'' O, and altitude 620 m). The BRS 8980 IPRO (BRS 8980), BMX 84I86 (Domínio), BMX 81I81RSF IPRO (Extrema), and BMX 8579 IPRO (Bonus) cultivars were evaluated on three sowing dates (11/29/2019, 01/14/2020, and 01/30/2020). The evaluation was conducted using soybean yield data collected in value for cultivation and use (VCU) experiments conducted by Embrapa Meio-Norte at Celeiro farm, Serra do Quilombo, Bom Jesus, PI, during four harvests and involving 61 genotypes. The best statistical indexes showing the efficiency of the calibration process were observed for the BRS 8980 (first sowing season) and Bônus (third sowing season) cultivars, with R2 and D indexes above 0.90. The total biomass production showed high agreement with the measured values, capturing the decrease in production due to the sowing date. The model captured the variability depending on the sowing dates and the yield for simulations of four other agricultural seasons, independent of the season in which the model was calibrated. It was concluded that the model satisfactorily simulated plant growth and soybean grain yield for the conditions of the Cerrado of the Southwestern region of Piaui. CSMCROPGROSoybean CSM CROPGRO Soybean Piaui 20192020 2019 2020 2019-202 Quilombo JesusPI Jesus PI 9º1620.3 9º16203 º 9º16 20.3 20 3 (9º16'20.3' S 44º4456.9 44º44569 44º44 56.9 56 9 44º44'56.9' O 62 m. m . m) 898 8980, , 8980) I 84I8 Domínio, Domínio (Domínio) IRSF RSF Extrema, Extrema (Extrema) 857 Bonus (Bonus 11/29/2019, 11292019 11 29 (11/29/2019 01142020 01 14 01/14/2020 01/30/2020. 01302020 01/30/2020 30 01/30/2020) VCU (VCU MeioNorte Meio Norte farm 6 genotypes first third R 090 0 90 0.90 values date seasons calibrated 2019202 201 202 2019-20 9º1620 9º1620. 9º1 203 20. 2 (9º16'20.3 44º4456 44º4456. 44º4 569 56. 5 44º44'56.9 89 84I (Domínio (Extrema 85 11/29/2019 1129201 1 (11/29/201 0114202 01/14/202 0130202 01/30/202 09 0.9 201920 2019-2 9º162 9º (9º16'20. 44º445 44º 44º44'56. 8 11/29/201 112920 (11/29/20 011420 01/14/20 013020 01/30/20 0. 20192 2019- (9º16'20 44º44'56 11/29/20 11292 (11/29/2 01142 01/14/2 01302 01/30/2 (9º16'2 44º44'5 11/29/2 1129 (11/29/ 0114 01/14/ 0130 01/30/ (9º16' 44º44' 11/29/ 112 (11/29 011 01/14 013 01/30 (9º16 11/29 (11/2 01/1 01/3 (9º1 11/2 (11/ 01/ (9º 11/ (11 (1 (
15.
Clinical Characterization of Patients with Rare Diseases Who Had Covid-19 or Covid-19 Like Symptoms Covid19 Covid 19 Covid-1 Covid1 1 Covid-
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Magalhães, Ana Paula P. S. de
; Randon, Dévora N.
; Silva, Thiago O.
; Pereira, Natálya G.
; Souza, Carolina F. M. de
; Araújo, Ana Angélica L. B. de
; Silva, Raquel T. B. da
; Horovitz, Dafne D. G.
; Santos, Emerson de S.
; Pinto, Louise L. de C.
; Andrade, Maria Denise F. C. de
; Cruz, Pedro J. S. C.
; Schuler-Faccini, Lavinia
; Amartino, Hernan
; Refosco, Lília F.
; Poswar, Fabiano
; Vianna, Fernanda
; Poloni, Soraia
Schwartz, Ida V. D.

















Journal of Inborn Errors of Metabolism and Screening
- Journal Metrics
Abstract COVID-19 is an infectious disease caused by the SARS-CoV-2 virus, first identified in China, which later gave rise to a global pandemic. Little is known about the impact of COVID-19 on patients with rare diseases. More than 8,000 rare diseases have been identified, which makes this quite a significant contingent of patients. This study aims to characterize SARS-CoV-2 infection in unvaccinated patients with rare diseases. Data were collected by means of a specific form distributed to medical teams involved in the care of rare diseases and disseminated to communities of patients with rare diseases via social networks in Brazil and Argentina. COVID-19 infection was characterized in 75 patients (82.7% with confirmatory tests), both pediatric and adult (age 6 months to 64 years), representing 40 different genetic and non-genetic rare diseases. Inborn errors of metabolism (IEM) accounted for most genetic cases. Fifty-nine patients (78.7%) required medical care, of which 17 (22.6%) required hospitalization. Three patients (4%) died due to complications from COVID-19 (Glycogenosis type II, 50 years old; Mitochondrial Myopathy, 11 years and Trisomy 18, 0.5 years). Extreme patient ages and diseases characterized by muscle involvement were associated with worse COVID-19 outcomes. COVID19 COVID 19 COVID-1 SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- virus China pandemic 8000 8 000 8,00 Argentina 7 82.7% 827 82 (82.7 tests, tests , tests) age years, years) 4 nongenetic non IEM (IEM cases Fiftynine Fifty nine 78.7% 787 78 (78.7% 1 22.6% 226 22 (22.6% hospitalization 4% (4% Glycogenosis II 5 old Myopathy 18 05 0 0. years. . outcomes COVID1 COVID- SARS-CoV 800 00 8,0 82.7 (82. 78.7 (78.7 22.6 (22.6 (4 80 8, 82. (82 78. (78. 22. (22. ( (8 (78 (22 (7 (2
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