Search | SciELO

Abstract: This study determined the in vitro effects of ethyl nitroacetate (ENA), ethyl 2-nitropropionate (E-2-NPP) and 3-nitropropionic acid (NPA) on ruminal production of CH4, H2, volatile fatty acids (VFAs) and in vitro dry matter disappearance of ground alfalfa. In vitro incubations were carried out over 24-h succeeding days (3 batches). Total gas and methane production decreased with all nitro compounds (P < 0.05) in all the batches. Total production of VFAs was reduced by ENA and E-2- NPP (P < 0.05), but not by NPA. DM disappearance was similar between treatments but decreased across batches. Further studies should be aimed at understanding the impact of NPA on ruminal metabolism, as well as its effect on in vivo models.

https://doi.org/10.29393/chjaas40-18enpa100018

Barriers and facilitators to vaccination in Latin America: a thematic synthesis of qualitative studies
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Roberti, Javier

; Ini, Natalí

; Belizan, Maria

; Alonso, Juan Pedro

Cadernos de Saúde Pública

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2024, Volume 40 N. 6 elocation e00165023

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

As vacinas são frequentemente subvalorizadas ou subutilizadas por uma série de razões. A hesitação vacinal é um desafio global, sendo uma ameaça à aceitação das vacinas e aos objetivos dos programas de imunização. O objetivo desta revisão é descrever barreiras e facilitadores para a vacinação na América Latina. O desenho do estudo foi uma revisão sistemática e síntese temática de estudos qualitativos sobre conhecimento ou atitudes de adultos, pais de crianças em idade de vacinação, adolescentes e profissionais de saúde sobre vacinação na América Latina. As bases de dados analisadas foram PubMed, CENTRAL, Scopus, LILACS, SciELO e CINAHL. Foram incluídos 56 estudos. Os facilitadores incluíram a ideia de que a vacinação era reconhecida como uma estratégia eficaz para prevenir doenças infecciosas e um requisito para o acesso à assistência social, escolaridade ou emprego. Além disso, recomendações de profissionais de saúde e experiências positivas com serviços de saúde também foram identificados como fatores facilitadores. Os principais obstáculos foram a falta de informação ou aconselhamento, problemas estruturais como escassez de vacinas e horário limitado de funcionamento, incapacidade de comprar vacinas pagas ou se transportar para unidades de saúde, certas crenças religiosas, concepções erradas sobre vacinas e preocupações de segurança. A pesquisa qualitativa pode contribuir para a compreensão das percepções e tomadas de decisão sobre a vacinação e para o desenvolvimento de políticas e intervenções para aumentar a cobertura vacinal.

Vaccines are often undervalued or underused for a variety of reasons, and vaccine hesitancy is a global challenge that threatens vaccine acceptance and the goals of immunization programs. This review aimed to describe the barriers and facilitators to vaccination in Latin America. The study design was a systematic review and thematic synthesis of qualitative studies reporting on the knowledge or attitudes of adults, parents of children at vaccination age, adolescents and health professionals towards vaccination in Latin America. The databases searched were PubMed, CENTRAL, Scopus, LILACS, SciELO, and CINAHL. A total of 56 studies were included. Facilitators included vaccination being recognized as an effective strategy for preventing infectious diseases and as a requirement for access to social assistance programs, schooling or employment. Recommendations from health professionals and positive experiences with health services were also identified as facilitators. The main barriers were lack of information or counseling, structural problems such as shortages of vaccines and limited hours of operation, the inability to afford over-the-counter vaccines or transportation to health facilities, certain religious beliefs, misconceptions and safety concerns. Qualitative research can contribute to understanding perceptions and decision-making about vaccination and to designing policies and interventions to increase coverage.

Las vacunas suelen estar subvaloradas o desaprovechadas por diversas razones. La vacilación ante las vacunas es un desafío global y representa una amenaza para la aceptación de las vacunas y para los objetivos de los programas de inmunización. El objetivo de esta revisión es describir las barreras y los facilitadores de la vacunación en América Latina. El diseño del estudio fue una revisión sistemática y una síntesis temática de estudios cualitativos sobre conocimientos o actitudes de adultos, padres de niños en edad de vacunación, adolescentes y profesionales de la salud sobre la vacunación en América Latina. Las bases de datos analizadas fueron PubMed, CENTRAL, Scopus, LILACS, SciELO y CINAHL. Se incluyeron 56 estudios. Los facilitadores incluyeron la idea de que la vacunación era reconocida como una estrategia eficaz para prevenir enfermedades infecciosas y un requisito para el acceso a la asistencia social, la escolaridad o el empleo. También se identificaron como factores facilitadores las recomendaciones de los profesionales de la salud y las experiencias positivas con los servicios de salud. Los principales obstáculos fueron la falta de información o asesoramiento, problemas estructurales como la escasez de vacunas y los horarios de funcionamiento limitados, la imposibilidad de pagar vacunas no provistas de forma gratuita o de desplazarse a los centros de salud, ciertas creencias religiosas, conceptos erróneos sobre las vacunas y preocupaciones por la seguridad. La investigación cualitativa puede contribuir a la comprensión de las percepciones y a la toma de decisiones sobre la vacunación y al desarrollo de políticas e intervenciones para aumentar la cobertura de vacunación.

https://doi.org/10.1590/0102-311xen165023

Vaccination status and outcomes in critical COVID-19 patients COVID19 COVID 19 COVID-1 COVID1 1 COVID-
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Costa, Pedro Nogueira

; Pereira, João Oliveira

; Cañigral, Aurea Higon

; Quintana, Elena Martinez

; Sanchez-Nieto, Juan Miguel

; Delis, Pablo Bayoumy

; Villarroya, Ana Renedo

; Gomez, Laura Lopez

; Fernandez, Nuria Alonso

; Alcaraz, Andrés Carrillo

Jornal Brasileiro de Pneumologia

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2024, Volume 50 N. 1 elocation e20230116

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Analisar as características clínicas e desfechos de pacientes com insuficiência respiratória aguda por COVID-19 com base na situação vacinal no momento da admissão na UTI. Métodos: Estudo observacional retrospectivo com um banco de dados prospectivo de pacientes admitidos na UTI de um hospital universitário em Múrcia, na Espanha, entre 1º de janeiro de 2021 e 1º de setembro de 2022. Dados clínicos, analíticos e sociodemográficos foram coletados e analisados com base na situação vacinal dos pacientes. Por meio de pareamento por escore de propensão, foram realizados ajustes de modo a levar em conta as variáveis de confusão. Além disso, foram calculadas as OR ajustadas e IC95%. Resultados: Foram incluídos no estudo 276 pacientes. Destes, 8,3% apresentavam vacinação completa, 12% apresentavam vacinação incompleta e 79,7% não haviam sido vacinados. Embora os pacientes com vacinação completa apresentassem mais comorbidades, os com vacinação incompleta apresentavam doença mais grave. A proporção de pacientes com insuficiência respiratória aguda grave foi maior nos não vacinados, seguidos daqueles com vacinação incompleta. Não foram observadas diferenças significativas entre os diferentes grupos quanto a complicações, tempo de suporte ventilatório ou tempo de internação na UTI/hospital. Na amostra selecionada pelo pareamento por escore de propensão, o número de pacientes com complicações graves e a taxa de mortalidade hospitalar foram maiores em pacientes não vacinados, mas as diferenças não foram significativas. Conclusões: Este estudo não conseguiu demonstrar uma melhoria significativa dos desfechos em pacientes com COVID-19 em estado crítico e vacinados contra o SARS-CoV-2. No entanto, os IC foram amplos e as estimativas pontuais de mortalidade favoreceram os pacientes que receberam pelo menos uma dose de vacina contra a COVID-19. Objetivo COVID19 COVID 19 COVID-1 Métodos Múrcia Espanha º 202 2022 clínicos propensão confusão disso IC95 IC95% Resultados 27 Destes 83 8 3 8,3 12 797 79 7 79,7 comorbidades UTIhospital UTI/hospital Conclusões SARSCoV2. SARSCoV2 SARSCoV SARS CoV 2. 2 SARS-CoV-2 entanto COVID19. 19. COVID1 1 COVID- 20 IC9 8, 79, SARS-CoV- SARS-CoV

ABSTRACT Objective: To analyze the clinical characteristics and outcomes of patients with COVID-19-related acute respiratory failure on the basis of their vaccination status at the time of ICU admission. Methods: We conducted a retrospective observational study using a prospective database of patients admitted to the ICU of a university hospital in the city of Murcia, in Spain, between January 1, 2021 and September 1, 2022. Clinical, analytical, and sociodemographic data were collected and analyzed on the basis of patient vaccination status. We adjusted for confounding variables using propensity score matching and calculated adjusted ORs and 95% CIs. Results: A total of 276 patients were included in the study. Of those, 8.3% were fully vaccinated, 12% were partially vaccinated, and 79.7% were unvaccinated. Although fully vaccinated patients had more comorbidities, partially vaccinated patients had higher disease severity. The proportion of patients with severe acute respiratory failure was higher in the unvaccinated group, followed by the partially vaccinated group. No significant differences were found among the different groups regarding complications, duration of ventilatory support, or length of ICU/hospital stay. In the sample selected by propensity score matching, the number of patients with severe complications and the in-hospital mortality rate were higher in unvaccinated patients, but the differences were not significant. Conclusions: This study failed to show a significant improvement in outcomes in critically ill COVID-19 patients vaccinated against SARS-CoV-2. However, the CIs were wide and the mortality point estimates favored patients who received at least one dose of COVID-19 vaccine. Objective COVID19related COVIDrelated COVID 19 related admission Methods Murcia Spain 1 202 2022 Clinical analytical 95 Results 27 those 83 8 3 8.3 12 797 79 7 79.7 comorbidities severity group support ICUhospital stay inhospital Conclusions COVID19 COVID-1 SARSCoV2. SARSCoV2 SARSCoV SARS CoV 2. 2 SARS-CoV-2 However vaccine 20 9 8. 79. COVID1 COVID- SARS-CoV- SARS-CoV

https://doi.org/10.36416/1806-3756/e20230116

Volumen, área y factor de forma nuclear neuronal en un modelo animal de diabetes pregestacional
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Isla Labrada, Yaliana

; Díaz Rojas, Pedro Augusto

; Toledo Hidalgo, Deimarys

; Alonso Trasobares, Meilin

; Fortuny, Susel Rodríguez

Revista Cubana de Investigaciones Biomédicas

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2024, Volume 43 elocation e2655

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Background: The brain during the prenatal stage is one of the organs most affected by teratogenic factors such as Pregestacional Diabetes Mellitus. Its effect on it during these stages requires greater knowledge because it is an important predictor of cognitive and psychological problem in age adult. For the study of the cerebral cortex, animal models are very useful, combined with morphometric techniques, greater precision will be obtained when establishing the causes to determinate the damage. Objective: To determine the possible differences of the nuclear morphometric indicators: area, volume and shape factor in the neurons of the temporal cerebral cortex of normal Wistar rat kits and in an animal model with pregestacional diabetes mellitus. Method: A basic experimental study was carried out with 16 brains of Wistar rats in the period from June 2021 to June 2022 at the University of Medical Sciences of Holguín. These brains were organized into two groups of eight each. A control group with those from healthy rat kits and a case group with brain from diabetic rats kits. Nuclear morphometric indicators such as area, volume and shape of factor were studied. Results: The area and the nuclear volume show superior values in the control group. The value of the shape factor did not show significant difference. Conclusions: the results obtained show that Pregestational Diabetes Mellitus can cause damage to the neurons of the nervous tissue of the brain area studied.

RESUMEN Fundamento: El cerebro durante la etapa prenatal es uno de los órganos más afectados por factores teratógenos, por ejemplo la Diabetes Mellitus Pregestacional. Su efecto sobre este en esta etapa requiere un mayor conocimiento porque es un importante predictor de problemas cognitivos y psicológicos en la edad adulta. Para el estudio de la corteza cerebral resultan muy útiles los modelos animales, combinados con técnicas morfométricas tendremos una mayor precisión a la hora de establecer las causas que condicionan el daño. Objetivo: Determinar las posibles diferencias de los indicadores morfométricos nucleares: área, volumen, y factor de forma en las neuronas de la corteza cerebral temporal de gazapos de ratas Wistar normal y en un modelo animal con diabetes mellitus pregestacional. Métodos: Se realizó un estudio experimental básico con 16 cerebros de gazapos de ratas Wistar en el período comprendido entre junio 2021 a junio 2022 en la Universidad de Ciencias Médicas de Holguín. Dichos cerebros se organizaron en dos grupos de ocho cada uno. Un grupo control con los procedentes de gazapos de ratas sanas y un grupo casos con los cerebros de gazapos de ratas diabéticas. Se estudiaron indicadores morfométricos nucleares como el área, el volumen y el factor de forma. Resultados: El área y el volumen nuclear muestran valores superiores en el grupo control .El valor del factor de forma no mostró diferencias. Conclusiones: Los resultados obtenidos traducen que la Diabetes Mellitus Pregestacional puede causar daño a las neuronas del tejido nervioso de la zona cerebral estudiada.

BEHIND THE PROTON PUMP INHIBITOR PRESCRIPTION: AN INTERNATIONAL SURVEY ON PHYSICIAN PRACTICES AND KNOWLEDGE PRESCRIPTION
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PIÑERÚA-GONSÁLVEZ, Jean Félix

; ZAMBRANO-INFANTINO, Rosanna del Carmen

; ALBORNOZ-SANDOVAL, Julio César

; TONG-MORAO, Pedro Waykin

; LEÓN-HERNÁNDEZ, Mariangel Nohemy

; MATHEUS-ALONSO, Barbara Daniela

; SUÁREZ-LÓPEZ, Frank

; FLORES, Yormalis

; HIGUERA, Santos Neomar

; RUIZ-REBOLLO, María Lourdes

; SULBARAN, Mariseli

Arquivos de Gastroenterologia

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2024, Volume 61 elocation e23153

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Contexto: Os inibidores da bomba de prótons (IBPs) são amplamente prescritos em todo o mundo, muitas vezes resultando em seu uso excessivo. Consequentemente, é essencial identificar as prováveis causas desse uso excessivo para facilitar sua prescrição adequada. Objetivo: Este estudo tem como objetivo avaliar o padrão de prescrição dos médicos, seu conhecimento sobre IBPs e fatores que afetam seu conhecimento. Métodos: Uma pesquisa on-line foi conduzida entre médicos latino-americanos e espanhóis, coletando os seguintes dados: informações profissionais, padrões de uso de IBP, familiaridade com evidências publicadas e abordagem de manejo em três casos-cenários hipotéticos. O conhecimento dos participantes foi categorizado em suficiente ou insuficiente com base nos resultados dos cenários de caso. Posteriormente, a análise de subgrupos foi realizada com base no nível de formação do médico, anos de prática, especialidade e tempo desde a última revisão da literatura dos IBPs. Resultados: Um total de 371 médicos participaram da pesquisa. Trinta e oito por cento prescrevem frequentemente IBP, principalmente para fins profiláticos (57,9%). Oitenta por cento não estavam familiarizados com as estratégias de prescrição de IBP, e 54,4% raramente revisaram a indicação contínua de pacientes em uso de IBP. Sessenta e quatro por cento demonstraram conhecimento suficiente nos cenários-caso. Observou-se associação significativa entre o tipo de especialidade (médica vs cirúrgica: 69,4% vs 46,8%, P<0,001), o momento da revisão da literatura de indicação do IBP (<5 anos vs >5 anos: 71,4% vs 58,7%, P=0,010) e conhecimento suficiente. Conclusão: Embora a maioria dos participantes prescrevesse IBPs regularmente e para fins de profilaxia, no entanto, não estava familiarizada com estratégias de prescrição e raramente revisava as indicações em andamento. O conhecimento suficiente está correlacionado com revisões recentes da literatura e afiliação à especialidade médica. Contexto (IBPs mundo Consequentemente adequada Objetivo Métodos online on line latinoamericanos latino americanos espanhóis dados profissionais casoscenários casos hipotéticos caso Posteriormente médico prática Resultados 37 57,9%. 579 57,9% . 57 9 (57,9%) 544 54 4 54,4 cenárioscaso. cenárioscaso cenários-caso Observouse Observou se médica cirúrgica 694 69 69,4 468 46 8 46,8% P<0,001, P0001 P P<0,001 , 0 001 P<0,001) <5 5 (< > 714 71 71,4 587 58 7 58,7% P=0,010 P0010 010 Conclusão profilaxia entanto andamento 3 57,9 (57,9% 54, 6 69, 46,8 P000 P<0,00 00 < ( 71, 58,7 P=0,01 P001 01 57, (57,9 46, P00 P<0,0 58, P=0,0 (57, P0 P<0, P=0, (57 P<0 P=0 (5 P< P=

ABSTRACT Background: Proton pump inhibitors (PPIs) are widely prescribed worldwide, often resulting in their overuse. Consequently, it is essential to identify the likely causes of this overuse to facilitate their appropriate prescription. Objective: This study aims to assess physician prescribing patterns, their knowledge of PPIs, and factors affecting their knowledge. Methods: An online survey was conducted among Latin American and Spanish physicians, collecting the following data: professional information, patterns of PPI usage, familiarity with published evidence, and the management approach in three hypothetical case-scenarios. Participant knowledge was categorized as sufficient or insufficient based on the results of the case scenarios. Subsequently, subgroup analysis was performed based on physician training level, years in practice, specialty, and time since the last PPI literature review. Results: A total of 371 physicians participated in the survey. Thirty-eight percent frequently prescribe PPIs, primarily for prophylactic purposes (57.9%). Eighty percent were unfamiliar with PPI deprescribing strategies, and 54.4% rarely reviewed the ongoing indication of patients taking a PPI. Sixty-four percent demonstrated sufficient knowledge in the case-scenarios. A significant association was observed between specialty type (medical vs surgical: 69.4% vs 46.8%, P<0.001), the timing of the PPI indication literature review (<5 years vs >5 years: 71.4% vs 58.7%, P=0.010), and sufficient knowledge. Conclusion: While most participants prescribed PPIs regularly and for prophylaxis purposes, the majority were unfamiliar with deprescribing strategies and rarely reviewed ongoing indications. Sufficient knowledge is correlated with recent literature reviews and medical specialty affiliation. Background (PPIs worldwide Consequently prescription Objective Methods data information usage evidence casescenarios. casescenarios scenarios case-scenarios Subsequently level practice Results 37 Thirtyeight Thirty eight 57.9%. 579 57.9% . 57 9 (57.9%) 544 54 4 54.4 Sixtyfour Sixty four surgical 694 69 69.4 468 46 8 46.8% P<0.001, P0001 P P<0.001 , 0 001 P<0.001) <5 5 (< > 714 71 71.4 587 58 7 58.7% P=0.010, P0010 P=0.010 010 P=0.010) Conclusion indications affiliation 3 57.9 (57.9% 54. 6 69. 46.8 P000 P<0.00 00 < ( 71. 58.7 P001 P=0.01 01 57. (57.9 46. P00 P<0.0 58. P=0.0 (57. P0 P<0. P=0. (57 P<0 P=0 (5 P< P=

https://doi.org/10.1590/s0004-2803.24612023-153

Barriers and facilitators to vaccination in Latin America: a thematic synthesis of qualitative studies America
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Roberti, Javier

; Ini, Natalí

; Belizan, Maria

; Alonso, Juan Pedro

Cadernos de Saúde Pública

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2024, Volume 40 N. 6 elocation e00165023

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/0102-311xen165023

Prognostic value of programmed cell death ligand 1 (PD-L1) expression in patients with stage III non-small cell lung cancer under different treatment types: a retrospective study PDL1 PDL PD L1 L (PD-L1 nonsmall non small types (PD-L
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Castro, Nicoly Marques de

; Moura, Fernando

; Hada, Aline Lury

; Garcia, Diogo

; Victor, Elivane da Silva

; Schvartsman, Gustavo

; Carvalho, Leonardo

; Fernandes, Milena Lourenço Coleta

; Martins, Rodrigo de Souza

; Silva, Elaine Ferreira da

; Santos, Sarah Silva Mello Batista dos

; Taniwaki, Letícia

; Taranto, Patrícia

; Pontes, Janaina

; Beal, Juliana Rodrigues

; Dutra, Ana Carolina Pereira

; Oliveira Filho, João Bosco de

; Araujo, Sérgio Eduardo Alonso

; Usón Junior, Pedro Luiz Serrano

einstein (São Paulo)

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2024, Volume 22 elocation eAO0575

Abstract: En | Text: En | PDF: En

ABSTRACT Objective Currently programmed cell death protein 1 (PD-1) inhibitors in combination with other therapies are being evaluated to determine their efficacy in cancer treatment. However, the effect of PD-ligand (L) 1 expression on disease outcomes in stage III (EC III) non-small cell lung cancer is not completely understood. Therefore, this study aimed to assess the influence of PD-L1 expression on the outcomes of EC III non-small cell lung cancer. Methods This study was conducted on patients diagnosed with EC III non-small cell lung cancer who underwent treatment at a tertiary care hospital. PD-L1 expression was determined using immunohistochemical staining, all patients expressed PD-L1. Survival was estimated using the Kaplan-Meier method. Relationships between variables were assessed using Cox proportional regression models. Results A total of 49 patients (median age=69 years) with EC III non-small cell lung cancer and PD-L1 expression were evaluated. More than half of the patients were men, and most were regular smokers. The patients were treated with neoadjuvant chemotherapy, surgery, or sequential or combined chemotherapy and radiotherapy. The median progression-free survival of the entire cohort was 14.2 months, and the median overall survival was 20 months. There was no significant association between PD-L1 expression and disease progression, clinical characteristics, or overall survival. Conclusions PD-L1 expression was not correlated with EC III non-small cell lung cancer outcomes. Whether these findings differ from the association with immune checkpoint inhibitors remains to be addressed in future studies. PD1 PD (PD-1 However PDligand ligand L (L nonsmall non small understood Therefore PDL1 PDL L1 PD-L hospital staining PDL1. L1. KaplanMeier Kaplan Meier method models 4 age69 age 69 age=6 years men smokers surgery radiotherapy progressionfree progression free 142 14 2 14. months characteristics studies (PD- age6 6 age= (PD

https://doi.org/10.31744/einstein_journal/2024ao0575

Traducción, adaptación cultural y validación de la Escala de Apoyo a Políticas Asociadas al Alcohol en universitarios mexicanos
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González-Angulo, Pedro

; Alonso-Castillo, María Magdalena

; García, Karla Selene López

; Ortiz-Rodríguez, Jeyle

; Ventura, Carla Aparecida Arena

Revista de Enfermagem Referência

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dec 2023, Volume serVI N. 2 elocation e22023

Abstract: En Pt Es | Text: En Pt Es | PDF: En | PDF: Pt | PDF: Es

Abstract Background: Health protection through prevention and reduction of alcohol consumption is a public health priority. Some scales have been identified to assess public alcohol policies but in English language. Objective: To evaluate the psychometric properties of the translation and cultural adaptation of a scale to assess support for alcohol policies in young Mexican university students. Methodology: Methodological study, with the participation of 367 university students from southern Mexico. Construct validity was estimated by means of an exploratory factor analysis and the internal consistency of the questionnaire was checked to verify its reliability. Results: Internal consistency was 0.96. Construct validity was performed through exploratory factor analysis, identifying a three factors structure: harm reduction, marketing and information, and price and availability. Conclusion: The scale showed adequate reliability and validity, and can be applied in Spanish as an empirical indicator in studies concerning alcohol public policies in young university students.

Resumo Enquadramento: A proteção da saúde através da prevenção e redução do consumo de álcool é uma prioridade de saúde pública. Foram identificadas algumas escalas para avaliar as políticas públicas em matéria de álcool, mas em língua inglesa. Objetivo: Avaliar as propriedades psicométricas da tradução e adaptação cultural de uma escala para avaliar o apoio às políticas sobre o álcool em jovens estudantes universitários mexicanos. Metodologia: Estudo metodológico, com a participação de 367 estudantes universitários do sul do México. A validade do constructo foi estimada através de uma análise exploratória dos fatores e a consistência interna do questionário foi verificada para verificar a sua fiabilidade. Resultados: A consistência interna foi de 0,96. A validade de constructo foi realizada por médio de análise fatorial exploratória, identificando uma estrutura de três fatores: redução de danos, marketing e informação, e preço e disponibilidade. Conclusão: A escala mostrou fiabilidade e validade adequadas, e pode ser aplicada em espanhol como um indicador empírico em estudos relativos a políticas públicas sobre o álcool em jovens estudantes universitários.

Resumen Marco contextual: La protección de la salud por medio de la prevención y la reducción del consumo de alcohol es una prioridad para la salud pública. Se han identificado algunas escalas para evaluar políticas públicas de alcohol, pero en idioma inglés. Objetivo: Evaluar las propiedades psicométricas de la traducción y adaptación cultural de una escala para evaluar el apoyo a políticas de alcohol en jóvenes universitarios mexicanos. Metodología: Estudio metodológico, con la participación de 367 estudiantes universitarios del sur de México. La validez del constructo se estimó mediante un análisis factorial exploratorio y se verificó la consistencia interna del cuestionario para comprobar su fiabilidad. Resultados: La consistencia interna fue de 0.96. La validez de constructo se realizó mediante el análisis factorial exploratorio y se identificó una estructura de tres factores: la reducción del daño, el mercadeo e información, y el precio y la disponibilidad. Conclusión: La escala mostró fiabilidad y validez adecuada, y puede ser aplicada en español como indicador empírico en estudios referentes a las políticas públicas de alcohol en jóvenes universitarios.

https://doi.org/10.12707/rvi22023

Evaluación de la salud ambiental del río Ocloro, utilizando una metodología mixta
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Chaves-Villalobos, María

; Quirós-Vega, Jose

; Cordero-Cordero, Stephanie

; Villalobos-Sequeira, Jenny

; Anchía-Leitón, Deivis

; Loría-Barquero, Alonso

; Luna-Salas, Daniela

; Fung-Méndez, Ana

; Paniagua-Pantoja, Mónica

Revista Tecnología en Marcha

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dec 2023, Volume 36 N. 4 Pages 148 - 159

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract The sustainability of urban areas nowadays faces significant challenges, due to high levels of pollution caused by population density. Therefore, the availability of water resources appears to be becoming increasingly compromised, as a result of inappropriate management of the solid and liquid waste generated by different human activities. The Ocloro River is a clear example of this problem, as evidenced by the deterioration of its environmental health. A mixed methodology was used to know about it, the first method was to characterize water quality using physicochemical and microbiological parameters, later on, the determination of the Duch index, giving a total of 16 samples of class 5 “extreme contamination” and 4 samples of class 4 “severe contamination”, from 2019 to 2021. In the second stage, a perception survey was conducted among a specific sector of the Barrio Luján population, approaching information from 80 homes, where 54 people indicated that the river pollution had affected them; additionally, the majority rated the level of pollution as 8, where 10 was the value with the highest level of pollution. Finally, the POSH method was used, which allowed the identification of some of the main point sources of pollution near the river, determining 27.1 % of high pollution, 22.3 % of moderate pollution, and 50,6 % of reduced pollution; this last one corresponds to the northern part of the river micro-basin in the communities of San Pedro, Los Yoses, and Francisco Peralta.

Resumen La sostenibilidad de las zonas urbanas hoy en día enfrenta grandes desafíos, debido a los altos niveles de contaminación causados por la densidad poblacional. Por consiguiente, la disponibilidad del recurso hídrico se ve cada vez más comprometido, producto a la inapropiada gestión de residuos sólidos y líquidos, generados por diferentes actividades humanas. El río Ocloro es un claro ejemplo de esta problemática, el deterioro de su salud ambiental es una evidencia de ello. Para conocerla, se utilizó una metodología mixta, el primer método fue la caracterización de la calidad del agua mediante parámetros fisicoquímicos y microbiológicos, posteriormente, la determinación del índice holandés, obteniendo un total de 16 muestras clase 5 “contaminación muy severa” y 4 muestras clase 4 “contaminación severa”, del 2019 al 2021. En la segunda etapa se aplicó una encuesta de percepción entre un sector específico de la población de Barrio Luján, alcanzando información de 80 viviendas, donde 54 personas indicaron haber tenido afectación por la contaminación del río; asimismo, la mayoría calificó el nivel de contaminación en 8, donde 10 era el valor con mayor nivel de contaminación. Finalmente se utilizó el método POSH, el cual permitió identificar algunas de las principales fuentes puntuales de contaminación en las cercanías del río, determinando 27,1 % de contaminación elevada, 22,3 % de contaminación moderada y 50,6 % de contaminación reducida; este último le corresponde a la parte norte de la microcuenca en los barrios de San Pedro, Los Yoses y Francisco Peralta.

https://doi.org/10.18845/tm.v36i4.6392

10.

Third National Registry of Cardiac Rehabilitation Programs in Mexico (RENAPREC III-2022)
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Lara-Vargas, Jorge A.

; Ilarraza-Lomelí, Hermes

; García-Saldivia, Marianna

; Pineda-García, Alfredo D.

; Leyva-Valadez, Eduardo A.

; Justiniano-Cordero, Samuel

; Sahagún-Olmos, Roberto

; Zavala-Ramírez, Juana

; Cassaigne-Guasco, María E.

; Sánchez-Limón, Edgar-F

; Castañeda-López, Javier

; Cerón-Enríquez, Norma

; Ku-González, Andrés

; Arteaga-Martínez, Rodolfo

; Hinojosa-López, Tania

; Vergara-Guzmán, Jéssica

; Pérez-Vázquez, Daniel I.

; Gasca-Zamudio, Pedro D.

; Aranda-Ayala, Zulema L.

; Vacío-Reyes, Martha E.

; Reza-Orozco, Marco

; Alcocer-Gamboa, Miguel A.

; Hernández-González, Pedro A.

; Pérez-Reyes, Angélica A.

; Núñez-Urquiza, Juan P.

; Alonso-Sánchez, Jesús

; Franco-Valles, Sarahí

; Romo-Escamilla, Ricardo E.

; Nuriulú-Escobar, Patricia

; Serna-Santamaría, Iván

; Avilés-González, Jorge

; Salgado-Solorio, María C.

; Muñoz-Gutiérrez, Luz M.

; Mendoza-Díaz, Pedro M.

; Ávila-Estrada, Ángel

; Morales-Medina, Carlos

; Lara-Vázquez, Eduardo

; Rodríguez-Herrera, Paulina

; Galván-López, María

; Segoviano-Mendoza, Georgina

; De-la-Torre-Cruz, Fabiola

; Jiménez-Campos, Cecilia

; Ramírez-Meléndez, Alejandra

; Almaraz-Ríos, Alejandro

; González-Bonilla, Mezthly

; Rojano-Castillo, Jessica

; Rius-Suarez, María D.

Archivos de cardiología de México

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dec 2023, Volume 93 N. 4 Pages 405 - 416

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

resumen está disponible en el texto completo

Abstract Introduction: In Mexico, cardiac rehabilitation (CR) as an interdisciplinary intervention with therapeutic impact in patients with heart disease is growing. There is the need to know actual conditions of CR in our country. Objectives: The objective of this National Registry is to follow-up those existing and new CR units in Mexico through the comparison between the two previous registries, RENAPREC-2009 and RENAPREC II-2015 studies. This is a descriptive study focused on diverse CR activities such as assistance training, and certification of health professionals, barriers, reference, population attended, interdisciplinarity, permanence over time, growth prospects, regulations, post-pandemic condition, integrative characteristics, and scientific research. Results: Data were collected from 45 CR centers in the 32 states, 75.5% are private practice units, 67% are new, 33% were part of RENAPREC II-2015, and 17 have continued since 2009. With a better distribution of CR units along the territory, the median reference of candidates for CR programs is 9% with a significant reduction into tiempo of enrollment to Phase II admission (19 ± 11 days). Regarding to previous registries, the coverance of Phases I, II, and III is 71%, 100%, and 93%, respectively; and a coverance increases in evaluation, risk stratification, and prescription, more comprehensive attendance and prevention strategies. Conclusions: CR in Mexico has grown in the past 7 years. Even there is still low reference and heterogeneity in specific processes, there are strengths such as interdisciplinarity, scientific professionalization of specialists, national diversification, and an official society that are consolidated over time.

https://doi.org/10.24875/acm.22000235

11.

Nuevos inhibidores de aminopeptidasa N, aminopeptidasa A y dipeptidil peptidasa IV con potenciales aplicaciones biomédicas en cáncer
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Pascual Alonso, Isel

; Arrebola Sánchez, Yarini

; Charli, Jean Louis

; Sánchez Ramírez, Belinda

; Díaz Guevara, Lisset

; Valdés Tresanco, Mario Ernesto

; Valiente Flores, Pedro A.

; Rivera Méndez, Laura

; García Rodríguez, Gabriela

; Almeida García, Fabiola

; Bergado Baez, Gretchen

; Chávez, María de los Ángeles

; Chappé Pacheco, Mae

; Pedroso Reynaldo, Alejandro

Anales de la Academia de Ciencias de Cuba

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aug 2023, Volume 13 N. 2 elocation e1273

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: Cancer is the second leading cause of death in our country and in the world. Within the attractive targets for the design of new anticarcinogenic agents we find aminopeptidases. In particular, within the M1 family, the neutral aminopeptidase (APN, EC 3.4.11.2), the acid aminopeptidase (APA, EC 3.4.11.7) and within the S9 family of serine peptidases, the enzyme dipeptidyl peptidase IV (DPP-IV, EC 3.4.14.5); the before mentioned are targets established for the development of new anticancer agents due to their over-expression in different types of cancer. Considering the biomedical relevance of the inhibition of APN, APA and DPP-IV, the main goal of this paper is to identify new inhibitors of these enzymes with potential biomedical applications. Methods: They were addressed two strategies for the identification of new inhibitors of the enzymes under study: a) identification and biochemical characterization of new low molecular mass inhibitors of APN, APA and DPP-IV, for which virtual screenings were carried out in the base of low molecular mass compounds HitFinder, Maybridge (ThermoFisher), and b) biochemical characterization of the inhibition of APN, APA and DPP-IV by bestatin and bacitracin as new inhibitors of these enzymes. Subsequently, it was carried out the kinetic validation of the new identified inhibitors, they were carried out in silico structure: function relationship studies, it was also evaluated the biodistribution in a rat model as well as their cytotoxic effects on APN+/DPP-IV+ tumor lines. Results: They were identified and kinetically validated five new dual inhibitors of APN, APA and DPP-IV with non-competitive inhibition mechanisms in most cases. In silico studies of Enzyme: inhibitor complexes allowed the identification of non-conserved residues within the corresponding family and this lays the foundations for the rational design of highly selective APN, APA and DPP-IV inhibitors with greater biomedical potential. They were identified for the first time, using a methodology established in this work the presence of APN and DPP-IV in cancer tumor lines with high incidence and mortality in Cuba and the world. The new inhibitors have promising effects on these APN+/DPP-IV+ tumor lines. Conclusions: They are reported for the first-time new inhibitors of APN, APA and DPP-IV, with different inhibition mechanisms, some of them non-competitive, which are more advantageous from the therapeutic point of view than competitive inhibitors, with promising effects on tumor lines related to cancers with high incidence and mortality in Cuba.

RESUMEN Introducción: El cáncer constituye la segunda causa principal de muerte en nuestro país y en el mundo. Dentro de los blancos atractivos para el diseño de nuevos agentes anticancerígenos encontramos las aminopeptidasas. En particular, dentro de la familia M1, la aminopeptidasa neutra (APN, EC 3.4.11.2) y la aminopeptidasa ácida (APA, EC 3.4.11.7) y dentro de la familia S9 de las peptidasas serino, la enzima dipeptidil peptidasa IV (DPP-IV, EC 3.4.14.5) son blancos establecidos para el desarrollo de nuevos anticancerígenos debido a su sobreexpresión en diferentes tipos de cáncer. Teniendo en cuenta la relevancia biomédica de la inhibición de APN, APA y DPP-IV, el presente trabajo tiene como objetivo la identificación de nuevos inhibidores de estas enzimas con potenciales aplicaciones biomédicas. Métodos: Para la identificación de nuevos inhibidores de las enzimas en estudio se abordaron 2 estrategias de trabajo: a) identificación y caracterización bioquímica de nuevos inhibidores de APN, APA y DPP-IV de baja masa molecular para lo cual se realizaron cribados virtuales en la base de compuestos de baja masa molecular HitFinder, Maybrigde (ThermoFisher) y, b) caracterización bioquímica de la inhibición de APA, APA y DPP-IV por bestatina y bacitracina como nuevos inhibidores de estas enzimas. Posteriormente, se procedió a la validación cinética de los nuevos inhibidores identificados, se realizaron estudios de relación estructura: función in silico, se evaluó la biodistribución en modelo de rata así como se evaluaron sus efectos citotóxicos sobre líneas tumorales APN+/DPP-IV+. Resultados: Se identificaron y validaron cinéticamente 5 nuevos inhibidores duales de APN, APA y DPP-IV con mecanismos de inhibición de tipo no competitivo en la mayoría de los casos. Los estudios in silico de los complejos enzima: inhibidor permitieron la identificación de residuos no conservados dentro de la correspondiente familia y que sientan las bases para el diseño racional de inhibidores de APN, APA y DPP-IV altamente selectivos y con mayores potencialidades biomédicas. Se identificaron por primera vez la presencia de APN y DPP-IV en líneas tumorales de cáncer de alta incidencia y mortalidad en Cuba y el mundo, mediante una metodología establecida en el presente trabajo. Los nuevos inhibidores tienen efectos promisorios sobre estas líneas tumorales APN+/DPP-IV+. Como conclusiones, se informan por primera vez nuevos inhibidores de APN, APA y DPP-IV, con diferentes mecanismos de inhibición, algunos de ellos de tipo no competitivos, que resultan más ventajosos desde el punto de vista terapéutico que inhibidores competitivos, con efectos promisorios sobre líneas tumorales relacionadas con canceres de alta incidencia y mortalidad en Cuba.

12.

Consumo de cigarrillos de tabaco y bebidas alcohólicas: Experiencias significativas de adolescentes de complementos urbanos
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López Cisneros, Manuel Antonio

; Noh Moo, Pedro Moises

; Alonso Castillo, Maria Magdalena

RIDE. Revista Iberoamericana para la Investigación y el Desarrollo Educativo

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jun 2023, Volume 13 N. 26 elocation e070

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen El consumo de tabaco y alcohol se ha convertido en un problema de salud pública que afecta a los adolescentes debido al uso indiscriminado de cigarrillos de tabaco y a la ingesta excesiva de bebidas alcohólicas. El objetivo del presente estudio consistió en explorar el significado del consumo de cigarrillos de tabaco y bebidas alcohólicas en adolescentes habitantes de complementos urbanos desde la perspectiva del Interaccionismo Simbólico. El enfoque de la investigación fue cualitativo, descriptivo, transversal, con un muestreo teórico conformado por 42 adolescentes estudiantes de preparatoria. Como resultados emergieron tres categorías con sus respectivas subcategorías que fueron: proceso interpretativo (motivaciones), persuasión (influencia social) y evaluación personal (toma de decisiones). En conclusión, podemos decir que estos hallazgos permiten determinar la importancia del diseño de estrategias prioritarias de salud con enfoque multidisciplinario que impacten en la disminución, control y erradicación del consumo de drogas lícitas en adolescentes.

Abstract The consumption of tobacco and alcohol has become a public health problem that affects adolescents due to the indiscriminate use of tobacco cigarettes and the excessive intake of alcoholic beverages. The objective of this study was to explore the meaning of the consumption of tobacco cigarettes and alcoholic beverages in adolescents living in urban areas from the perspective of Symbolic Interactionism. The research approach was qualitative, descriptive, cross-sectional, with a theoretical sample made up of 42 adolescent high school students. As results, three categories emerged with their respective subcategories that were: interpretative process (motivations), persuasion (social influence) and personal evaluation (decision making). In conclusion, we can say that these findings make it possible to determine the importance of designing priority health strategies with a multidisciplinary approach that have an impact on the reduction, control, and eradication of licit drug use in adolescents.

Resumo O consumo de tabaco e álcool tornou-se um problema de saúde pública que atinge adolescentes devido ao uso indiscriminado de cigarros de tabaco e ingestão excessiva de bebidas alcoólicas. O objetivo deste estudo foi explorar o significado do consumo de cigarros de tabaco e bebidas alcoólicas em adolescentes residentes em áreas urbanas sob a ótica do Interacionismo Simbólico. A abordagem da pesquisa foi qualitativa, descritiva, transversal, com amostra teórica composta por 42 adolescentes estudantes do ensino médio. Como resultados emergiram três categorias com suas respectivas subcategorias que foram: processo interpretativo (motivações), persuasão (influência social) e avaliação pessoal (tomada de decisão). Em conclusão, podemos dizer que esses achados permitem determinar a importância do desenho de estratégias prioritárias de saúde com abordagem multidisciplinar que tenham impacto na redução, controle e erradicação do uso de drogas lícitas em adolescentes.

https://doi.org/10.23913/ride.v13i26.1533

13.

Identificación y sensibilidad antibiótica directas desde el hemocultivo positivo para bacilos gram negativos. Rendimiento comparativo de los sistemas Vitek 2C y Phoenix
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Carrion, Natalia Andrea

; Soloaga, Rolando Noel

; Asenzo, Camila

; Molina Abalos, Facundo Martín

; Ratti, María Serafina

; Diez, Adriana Susana

; Pidone, Juan Carlos

; Mamani, Víctor Alonso

Acta bioquímica clínica latinoamericana

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jun 2023, Volume 57 N. 2 Pages 221 - 225

Abstract: Es Pt En | Text: Es Pt En | PDF: Es | PDF: Pt | PDF: En

Resumen El objetivo de este estudio fue comparar los resultados de las pruebas de identificación y sensibilidad antimicrobiana obtenidos por los sistemas Vitek 2C (bioMérieux, Francia) y Phoenix (Becton Dickinson, EE.UU.) directamente a partir de hemocultivos positivos. Se realizó un estudio observacional prospectivo en el Hospital Naval Pedro Mallo de Buenos Aires, Argentina, que incluyó 70 bacteriemias monomicrobianas por gram negativos. Se obtuvo una identificación correcta por Vitek® 2C y por Phoenix del 100% y 97% respectivamente [p: no significativa (NS)]. La concordancia categórica para todos los antimicrobianos fue 97,1% y 98,1% (p: NS) con Vitek 2C y con Phoenix respectivamente. El tiempo medio para obtener un resultado fue de 10,19 h y 13,8 h (p: NS), respectivamente. Vitek 2C y Phoenix son herramientas importantes, rápidas y confiables para la identificación y las pruebas de sensibilidad realizadas directamente a partir de hemocultivos positivos.

Resumo O objetivo deste estudo foi comparar os resultados dos testes de identificação e de suscetibilidade antimicrobiana obtidos pelos sistemas Vitek 2C (bioMérieux, França) e Phoenix (Becton Dickinson, EUA) diretamente a partir de culturas de sangue positivas. Foi realizado um estudo observacional prospectivo no Hospital Naval Pedro Mallo em Buenos Aires, Argentina, incluindo 70 bacteriemias monomicrobianas devido a gram negativos. A identificação correcta por Vitek® 2C e Phoenix obtida foi de 100% e 97% respectivamente [p: não significativo (NS)]. O acordo categórico para todos os antimicrobianos foi de 97,1% e 98,1% (p: NS) com Vitek 2C e Phoenix respectivamente. O tempo médio para obter o resultado foi de 10,19 h e 13,8 h (p: NS), respectivamente. Vitek 2C e Phoenix são ferramentas importantes, rápidas e fiáveis para a identificação e testes de sensibilidade realizados diretamente a partir de hemoculturas positivas.

Abstract The aim of this study was to compare the results of identification and antimicrobial susceptibility tests obtained by the Vitek 2C (bioMérieux, France) and Phoenix (Becton Dickinson, USA) systems directly from positive blood cultures. A prospective observational study was performed at the Pedro Mallo Navy Hospital in Buenos Aires, Argentina, which included 70 monomicrobial bacteremias by gram negative rods. Correct identification by Vitek® 2C and Phoenix was 100% and 97%, respectively [p: not significant (NS)]. Categorical agreement for all antimicrobials was 97.1% and 98.1% (p: NS) with Vitek 2C and Phoenix, respectively. The mean time to result was 10.19 h and 13.8 h (p: NS), respectively. Vitek 2C and Phoenix are important, rapid and reliable tools for identification and susceptibility testing when performed directly from positive blood cultures.

14.

Efectos de la terapia con ventosas en pacientes con dolor lumbar
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Pérez-Cordeiro, Adrián

; Justo-Cousiño, Lorenzo A

; González-González, Yoana

; Alonso-Calvete, Alejandra

; Da Cuña-Carrera, Iria

Revista de la Asociación Española de Especialistas en Medicina del Trabajo

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2023, Volume 32 N. 1 Pages 54 - 74

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN. Introducción: El dolor lumbar es uno de los síntomas referidos con mayor frecuencia en la consulta médica, siendo un factor limitante en las actividades de la vida diaria y la actividad laboral. Las nuevas terapias, como el tratamiento con ventosas, parece aportar resultados prometedores al manejo del dolor lumbar. Objetivo: Evaluar la evidencia científica acerca de los efectos de la aplicación de terapia con ventosas en pacientes con dolor lumbar. Material y Métodos: Se realizó una búsqueda bibliográfica en PubMed, Medline, Cinhal, Scopus, Web of Science, PEDro y Cochrane con los términos “Cupping Therapy” y “Low Back Pain” y la palabra clave “Cupping Therapy”. Resultados: Se incluyeron 10 artículos que usaban la terapia con ventosas para el tratamiento de la lumbalgia, centrándose en las escalas de dolor y discapacidad y obteniendo resultados significativos beneficiosos. Conclusión: La terapia con ventosas parece disminuir el dolor y la discapacidad en pacientes con lumbalgia.

ABSTRACT Introduction: Low back pain is one of the most frequently referred symptoms in medical consultation, being a limiting factor in activities of daily living and work activity. New therapies, such as cupping, seem to bring promising results in the management of low back pain. Objective: To evaluate the scientific evidence on the effects of the application of cupping therapy in patients with low back pain. Material and Methods: A literature search was carried out in PubMed, Medline, Cinhal, Scopus, Web of Science, PEDro and Cochrane with the terms “Cupping Therapy” and “Low Back Pain” and the keyword “Cupping Therapy”. Results: 10 articles using cupping therapy for the treatment of low back pain were included, focusing on pain and disability scales and obtaining significant beneficial results. Conclusion: Cupping therapy appears to reduce pain and disability in patients with low back pain.

15.

KINESIOTAPING IN DISCOPATHIES AND DEGENERATIVE SPINAL DISEASES: SYSTEMATIC REVIEW DISEASES
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Vázquez, Javier Fernández

; Justo-Cousiño, Lorenzo Antonio

; Cuña-Carrera, Iria Da

; Alonso-Calvete, Alejandra

; González-González, Yoana

Coluna/Columna

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2023, Volume 22 N. 2 elocation e270983

Abstract: Es Pt En | Text: Es Pt En | PDF: Es | PDF: Pt | PDF: En

Resumen: El vendaje neuromuscular o kinesiotaping es una técnica de vendaje que se utiliza ampliamente en trastornos raquídeos. Sin embargo, se desconoce la evidencia científica de uso en discopatías y patología degenerativa de la columna. El objetivo de este trabajo consistió en analizar los ensayos clínicos publicados sobre el vendaje neuromuscular en sujetos con discopatías y lesiones degenerativas del raquis. Para ello, se realizó una búsqueda bibliográfica siguiendo las directrices PRISMA en las siguientes bases de datos: PubMed, Web of Science (WOS), Scopus, Medline y Cinahl. En el análisis de sesgo y calidad metodológica se utilizaron: escala PEDro, criterios de Van Tulder y análisis del riesgo de sesgo de la Colaboración Cochrane. Se incluyeron un total de 5 artículos que obtuvieron una puntuación media de 6,2 en la escala PEDro. Existe evidencia moderada de que, a corto plazo, el vendaje neuromuscular reduce el consumo de analgésicos, mejora el rango de movimiento y fuerza muscular en la musculatura posterior. Además, existe evidencia limitada de que puede mejorar la calidad, mientras que la evidencia científica sobre el efecto del vendaje neuromuscular en el dolor es contradictoria. La aplicación de vendaje neuromuscular es discopatías y procesos degenerativos del raquis debe realizarse con cautela a la espera de que se obtengan resultados más concluyentes y se valoren los efectos a largo plazo. Nivel de evidencia I; Revisión sistemática. Resumen raquídeos embargo columna ello datos PubMed WOS, WOS , (WOS) Scopus Cinahl utilizaron PEDro Cochrane 62 6 2 6, plazo analgésicos posterior Además contradictoria I sistemática (WOS

Resumo: A bandagem neuromuscular ou kinesiotaping é uma técnica de bandagem amplamente utilizada em distúrbios da coluna vertebral. Entretanto, a evidência científica para seu uso em discopatias e na patologia degenerativa da coluna são desconhecidas. Objetivo: O objetivo deste trabalho foi analisar ensaios clínicos publicados sobre bandagem neuromuscular em sujeitos com discopatias e lesões degenerativas da coluna vertebral. Para este fim, foi realizada uma pesquisa bibliográfica seguindo as diretrizes do PRISMA nas seguintes bases de dados: PubMed, Web of Science (WOS), Scopus, Medline e Cinahl. Na análise de viés e qualidade metodológica, foram utilizados: escala PEDro, critérios de Van Tulder e análise de risco de viés da Colaboração Cochrane. Um total de 5 artigos foi incluído com uma pontuação média de 6,2 na escala PEDro. Há evidências moderadas de que, a curto prazo, a bandagem neuromuscular reduz o consumo de analgésicos, melhora a amplitude de movimento e a força muscular na musculatura posterior. Além disso, há evidências limitadas de que pode melhorar a qualidade, enquanto as evidências científicas sobre o efeito da bandagem neuromuscular na dor são contraditórias. A aplicação da bandagem neuromuscular em discopatias e processos degenerativos da coluna vertebral deve ser feita com cautela até que resultados mais conclusivos sejam obtidos e os efeitos a longo prazo sejam avaliados. Nível de evidência I; Revisão sistemática. Resumo Entretanto desconhecidas Objetivo fim dados PubMed WOS, WOS , (WOS) Scopus Cinahl metodológica utilizados PEDro Cochrane 62 6 2 6, analgésicos posterior disso contraditórias avaliados I sistemática (WOS

ABSTRACT Neuromuscular taping or kinesiotaping is a technique widely used in spinal disorders. However, the scientific evidence of its use in discopathies and degenerative spine pathology is unknown. This study aimed to analyze the published clinical trials on neuromuscular taping in subjects with discopathies and degenerative spinal injuries. For this purpose, a literature search was performed following PRISMA guidelines in the following databases: PubMed, Web of Science (WOS), Scopus, Medline, and Cinahl. In analyzing bias and methodological quality, we used: the PEDro scale, Van Tulder criteria, and risk of bias analysis of the Cochrane Collaboration. A total of 5 articles were included that obtained a mean score of 6.2 on the PEDro scale. There is moderate evidence that, in the short term, neuromuscular taping reduces analgesic consumption and improves the range of motion and muscle strength in the posterior musculature. In addition, there is limited evidence that it can improve quality, while the scientific evidence on the effect of neuromuscular taping on pain is contradictory. The application of neuromuscular taping on discopathies and degenerative processes of the spine should be cautiously undertaken until more conclusive results are obtained, and the long-term effects are assessed. Level of evidence I; Systematic review. disorders However unknown injuries purpose databases PubMed WOS, WOS , (WOS) Scopus Medline Cinahl quality scale criteria Collaboration 62 6 2 6. term musculature addition contradictory longterm long assessed I review (WOS

https://doi.org/10.1590/s1808-185120222202270983

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Glossary and search help

You can enrich your search in a very simple way. Use the search indexes combined with the connectors (AND or OR) and specify more your search.

For example, if you want to search for articles about
cases of dengue in Brasil in 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

See below the complete list of search indexes that can be used:

Index code	Element
ti	article title
au	author
kw	article keywords
subject	subject (title words, abstract and keywords)
ab	abstract
ta	journal short title (e.g. Cad. Saúde Pública)
journal_title	journal full title (e.g. Cadernos de Saúde Pública)
la	publication language code (e.g. pt - Portuguese, es - Spanish)
type	document type
pid	publication identifier
publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

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