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Resumo Fundamento A ecocardiografia é essencial para avaliação do coração transplantado. No entanto, os valores de normalidade no transplante cardíaco (TC) não estão claramente definidos. Objetivos: Comparar parâmetros ecocardiográficos convencionais e pela técnica de Speckle Tracking entre pacientes transplantados cardíacos sem rejeição e uma população de indivíduos saudáveis. Métodos Foram estudados prospectivamente pacientes adultos, com menos de 1 ano de TC, que realizaram biópsia endomiocárdica de vigilância seguido de ecocardiograma transtorácico (ETT). Medidas convencionais de ETT acrescidas da avaliação de mecânica cardíaca por meio do Strain pelo Speckle Tracking foram realizadas e comparadas com um grupo de voluntários saudáveis. A significância estatística adotada para o estudo foi de 5%. Resultados Avaliou-se 36 pacientes transplantados sem rejeição, os quais foram comparados com 30 indivíduos saudáveis. Observou-se redução nos valores de Strain Global Longitudinal de Ventrículo Esquerdo em valor absoluto (11,99% transplantados, 20,60% controle, p<0,0001), Strain de parede livre de Ventrículo Direito (transplantados 16,67%, controle 25,50%, p<0,0001) e dos índices de trabalho miocárdico (p<0,0001), maior tamanho do átrio esquerdo (38,17 ml/m2 transplantados, controle 18,98 ml/m2, p<0,0001), maior índice de massa e espessura relativa das paredes (p<0,0001) e a presença da Doença de Chagas como principal etiologia para o transplante. Conclusão Os transplantados cardíacos estáveis e sem rejeição apresentaram diferenças com relação aos parâmetros ecocardiográficos comparados com indivíduos saudáveis. Estes achados indicam que medidas ecocardiográficas convencionais e de mecânica cardíaca são alteradas em transplantados mesmo na ausência de rejeição e podem ser relevantes para o contexto clínico e acompanhamento dos pacientes. transplantado entanto TC (TC definidos Objetivos saudáveis adultos ETT. . (ETT) 5 5% Avaliouse Avaliou se 3 Observouse Observou 11,99% 1199 11 99 (11,99 2060 20 60 20,60 p<0,0001, p00001 p p<0,0001 , 0 0001 1667 16 67 16,67% 2550 25 50 25,50% 38,17 3817 38 17 (38,1 mlm2 mlm ml m2 m ml/m 1898 18 98 18,9 (p<0,0001 (ETT 11,99 119 9 (11,9 206 2 6 20,6 p0000 p<0,000 000 166 16,67 255 25,50 38,1 381 (38, 189 18, (p<0,000 11,9 (11, 20, p000 p<0,00 00 16,6 25,5 38, (38 (p<0,00 11, (11 p00 p<0,0 16, 25, (3 (p<0,0 (1 p0 p<0, ( (p<0, p<0 (p<0 p< (p< (p

Abstract Background Echocardiography is essential for the assessment of patients with heart transplants. However, normal values in such individuals are not clearly defined. Objectives To compare conventional echocardiographic and speckle tracking variables between patients with unrejected heart transplants and healthy individuals. Methods : A prospective study was conducted with adult patients having undergone heart transplantation at least one year earlier and submitted to endomyocardial biopsy followed by transthoracic echocardiogram (TTE). Conventional TTE measures and mechanical heart strain assessments using speckle tracking were performed and the results were compared to those of a group of healthy volunteers. Statistical significance was set at 5% (p < 0.05). Results Thirty-six transplant patients without rejection were analyzed and compared to 30 healthy individuals. Chagas disease was the main reason for transplantation. Lower left ventricular global longitudinal strain expressed in absolute values was found (11.99% in transplant patients vs. 20.60% in controls; p <0.0001), right ventricular free wall longitudinal strain (16.67% in transplant patients vs. 25.50% in controls; p <0.0001) and myocardial work indices (p < 0.0001) as well as a larger size of the left atrium (38.17 ml/m2 in transplant patients vs. 18.98 ml/m2 in controls; p <0.0001) and greater mass and relative wall thickness (p <0.0001). Conclusion Stable patients having undergone heart transplants without rejection have differences concerning echocardiographic variables compared to healthy individuals. These findings indicate that conventional echocardiographic measures and heart mechanics are altered in transplant patients even in the absence of rejection. Such findings are relevant to the clinical context and follow-up of the patient. However defined TTE. . (TTE) volunteers 5 0.05. 005 0.05 0 05 0.05) Thirtysix Thirty six 3 11.99% 1199 11 99 (11.99 vs 2060 20 60 20.60 controls <0.0001, 00001 <0.0001 , 0001 16.67% 1667 16 67 (16.67 2550 25 50 25.50 0.0001 38.17 3817 38 17 (38.1 mlm2 mlm ml m2 m ml/m 1898 18 98 18.9 <0.0001. followup follow up patient (TTE 00 0.0 11.99 119 1 9 (11.9 206 2 6 20.6 0000 <0.000 000 16.67 166 (16.6 255 25.5 0.000 38.1 381 (38. 189 18. 0. 11.9 (11. 20. <0.00 16.6 (16. 25. 0.00 38. (38 11. (11 <0.0 16. (16 (3 (1 <0. ( <0

https://doi.org/10.36660/abc.20230681

Vaccination coverage, delay and loss to follow-up of the triple viral vaccine, in live births between 2017 and 2018 in Brazilian cities coverage followup follow up vaccine 201 20 2
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D’Agostini, Tatiana Lang

; Zambom, Fernanda Florencia Fregnan

; Moraes, José Cássio de

; França, Ana Paula

; Camargo, Jéssica Pires de

; Ribeiro, Manoel Carlos Sampaio de Almeida

; Barata, Rita Barradas

; Silva, Adriana Ilha da

; Ramos Jr., Alberto Novaes

; França, Ana Paula

; Oliveira, Andrea de Nazaré Marvão

; Boing, Antonio Fernando

; Domingues, Carla Magda Allan Santos

; Oliveira, Consuelo Silva de

; Maciel, Ethel Leonor Noia

; Guibu, Ione Aquemi

; Mirabal, Isabelle Ribeiro Barbosa

; Barbosa, Jaqueline Caracas

; Lima, Jaqueline Costa

; Moraes, José Cássio de

; Luhm, Karin Regina

; Caetano, Karlla Antonieta Amorim

; Lima, Luisa Helena de Oliveira

; Antunes, Maria Bernadete de Cerqueira

; Teixeira, Maria da Gloria

; Teixeira, Maria Denise de Castro

; Borges, Maria Fernanda de Sousa Oliveira

; Queiroz, Rejane Christine de Sousa

; Gurgel, Ricardo Queiroz

; Barata, Rita Barradas

; Azevedo, Roberta Nogueira Calandrini de

; Oliveira, Sandra Maria do Valle Leone de

; Teles, Sheila Araújo

; Gama, Silvana Granado Nogueira da

; Mengue, Sotero Serrate

; Simões, Taynãna César

; Nascimento, Valdir

; Araújo, Wildo Navegantes de

Epidemiologia e Serviços de Saúde

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2024, Volume 33 N. spe2 elocation e20231218

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo Estimar cobertura vacinal, atraso e perda de seguimento da vacina tríplice viral, em crianças até 24 meses residentes em cidades brasileiras. Método Inquérito domiciliar baseado em uma coorte retrospectiva de nascidos vivos em 2017-2018, que analisou cobertura e dados sociodemográficos das crianças e famílias, a partir dos registros da caderneta de vacinação e entrevista. Resultados A cobertura válida da primeira dose foi de 90,0% (IC95% 88,9;91,0), e da segunda, e 81,1% (IC95% 79,8;82,4). O atraso para ambas as doses foi de 23,2% (IC95% 21,9;24,5) e a perda de seguimento de 10,8% (IC95% 9,9;11,8). O estrato socioeconômico A apresentou menor cobertura e, à medida que a ordem de nascimento aumentava, menor era a cobertura para as duas doses. Crianças de mães com 13 a 15 anos de escolaridade apresentaram maior cobertura. Conclusão As coberturas não alcançaram a meta preconizada. Estratégias diferenciadas para dirimir dificuldade de acesso, desinformação e hesitação poderão melhorar a cobertura. vacinal viral 2 brasileiras 20172018, 20172018 2017 2018, 2018 2017-2018 famílias entrevista 900 90 0 90,0 IC95% IC95 IC (IC95 88,991,0, 889910 88,9 91,0 , 88 9 91 88,9;91,0) segunda 811 81 1 81,1 79,882,4. 798824 79,8 82,4 . 79 8 82 4 79,8;82,4) 232 23 23,2 21,924,5 219245 21,9 24,5 21 5 21,9;24,5 108 10 10,8 9,911,8. 99118 9,9 11,8 11 9,9;11,8) aumentava preconizada acesso 2017201 201 2017-201 90, IC9 (IC9 991 88,991,0 88991 889 88, 910 91, 88,9;91,0 81, 882 79,882,4 79882 798 79, 824 82, 7 79,8;82,4 23, 924 21,924, 21924 219 21, 245 24, 21,9;24, 10, 911 9,911,8 9911 99 9, 118 11, 9,9;11,8 201720 20 2017-20 (IC 88,991, 8899 88,9;91, 79,882, 7988 79,8;82, 92 21,924 2192 21,9;24 9,911, 9,9;11, 20172 2017-2 88,991 88,9;91 79,882 79,8;82 21,92 21,9;2 9,911 9,9;11 2017- 88,99 88,9;9 79,88 79,8;8 21,9; 9,91 9,9;1 88,9; 79,8; 9,9;

ABSTRACT Objective To estimate measles-mumps-rubella vaccination coverage, delay and loss to follow-up in children up to 24 months old living in Brazilian cities. Methods Surveys and questionnaires with a retrospective cohort of live births in 2017-2018, analyzing vaccination coverage and sociodemographic data of children and families, based on vaccination card records and interviews. Results Valid coverage of first dose was 90.0% (95%CI 88.9;91.0) and 81.1% for the second dose (95%CI 79.8;82.4). Delay for both doses was 23.2% (95%CI 21.9;24.5) and loss to follow-up was 10.8% (95%CI 9.9;11.8). Socioeconomic stratum A had the lowest vaccination coverage and the higher the child’s birth order, the lower the vaccination coverage for the second dose. Children whose mothers had 13 to 15 years of education had higher vaccination coverage. Conclusion Coverage did not meet the recommended target. Differentiated strategies to resolve difficulties in access, misinformation, and vaccination hesitancy will help improve vaccination coverage. measlesmumpsrubella measles mumps rubella followup follow 2 cities 20172018, 20172018 2017 2018, 2018 2017-2018 families interviews 900 90 0 90.0 95%CI 95CI CI 95 88.991.0 889910 88.9 91.0 88 9 91 88.9;91.0 811 81 1 81.1 79.882.4. 798824 79.8 82.4 . 79 8 82 4 79.8;82.4) 232 23 23.2 21.924.5 219245 21.9 24.5 21 5 21.9;24.5 108 10 10.8 9.911.8. 99118 9.9 11.8 11 9.9;11.8) childs child s order target access misinformation 2017201 201 2017-201 90. 991 88.991. 88991 889 88. 910 91. 88.9;91. 81. 882 79.882.4 79882 798 79. 824 82. 7 79.8;82.4 23. 924 21.924. 21924 219 21. 245 24. 21.9;24. 10. 911 9.911.8 9911 99 9. 118 11. 9.9;11.8 201720 20 2017-20 88.991 8899 88.9;91 79.882. 7988 79.8;82. 92 21.924 2192 21.9;24 9.911. 9.9;11. 20172 2017-2 88.99 88.9;9 79.882 79.8;82 21.92 21.9;2 9.911 9.9;11 2017- 88.9; 79.88 79.8;8 21.9; 9.91 9.9;1 79.8; 9.9;

resumen está disponible en el texto completo

https://doi.org/10.1590/s2237-96222024v33e20231218.especial2.en

Analysis of polio vaccination status in a cohort of live births in 2017 and 2018 in Brazilian cities: a national vaccination coverage survey 201 cities 20 2
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Franco, Alessandra Lucchesi de Menezes Xavier

; França, Ana Paula

; Moraes, José Cássio de

; Ribeiro, Manoel Carlos Sampaio de Almeida

; Silva, Adriana Ilha da

; Ramos Jr., Alberto Novaes

; França, Ana Paula

; Oliveira, Andrea de Nazaré Marvão

; Boing, Antonio Fernando

; Domingues, Carla Magda Allan Santos

; Oliveira, Consuelo Silva de

; Maciel, Ethel Leonor Noia

; Guibu, Ione Aquemi

; Mirabal, Isabelle Ribeiro Barbosa

; Barbosa, Jaqueline Caracas

; Lima, Jaqueline Costa

; Moraes, José Cássio de

; Luhm, Karin Regina

; Caetano, Karlla Antonieta Amorim

; Lima, Luisa Helena de Oliveira

; Antunes, Maria Bernadete de Cerqueira

; Teixeira, Maria da Gloria

; Teixeira, Maria Denise de Castro

; Borges, Maria Fernanda de Sousa Oliveira

; Queiroz, Rejane Christine de Sousa

; Gurgel, Ricardo Queiroz

; Barata, Rita Barradas

; Azevedo, Roberta Nogueira Calandrini de

; Oliveira, Sandra Maria do Valle Leone de

; Teles, Sheila Araújo

; Gama, Silvana Granado Nogueira da

; Mengue, Sotero Serrate

; Simões, Taynãna César

; Nascimento, Valdir

; Araújo, Wildo Navegantes de

Epidemiologia e Serviços de Saúde

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2024, Volume 33 N. spe2 elocation e20231303

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo Descrever a situação vacinal contra poliomielite em 26 capitais, Distrito Federal e 12 municípios do Brasil, em crianças nascidas em 2017 e 2018. Métodos Inquérito domiciliar de base populacional realizado de 2020 a 2022, em que se avaliou a cobertura vacinal da poliomielite em crianças, considerando doses válidas, aplicadas e oportunas por municípios. Resultados Foram coletados dados de 37.801 crianças. A cobertura vacinal de esquema completo de doses válidas foi de 87,5% (IC95% 86,2;88,7), caindo para 79,6% (IC95% 78,1;81,0), considerando a dose de reforço. A taxa de abandono foi de 4,5% para esquema completo, e de 11,7% no primeiro reforço. Não houve correlação entre a realização de campanha e as elevadas coberturas. Conclusão A cobertura vacinal de esquema completo e no primeiro reforço não atingiu a meta de 95,0%. Diferenças regionais e a associação das coberturas vacinais com indicadores sociais devem ser consideradas nas estratégias de aumento da cobertura. 2 capitais 1 Brasil 201 2018 202 2022 37801 37 801 37.80 875 87 5 87,5 IC95% IC95 IC (IC95 86,288,7, 862887 86,2 88,7 , 86 88 7 86,2;88,7) 796 79 6 79,6 78,181,0, 781810 78,1 81,0 78 81 0 78,1;81,0) 45 4 4,5 117 11 11,7 950 95 95,0% 20 3780 3 80 37.8 8 87, IC9 (IC9 288 86,288,7 86288 862 86, 887 88, 86,2;88,7 79, 181 78,181,0 78181 781 78, 810 81, 78,1;81,0 4, 11, 9 95,0 378 37. (IC 28 86,288, 8628 86,2;88, 18 78,181, 7818 78,1;81, 95, 86,288 86,2;88 78,181 78,1;81 86,28 86,2;8 78,18 78,1;8 86,2; 78,1;

ABSTRACT Objective To describe the polio vaccination status in 26 state capitals, the Federal District, and 12 municipalities in Brazil, among children born between 2017 and 2018. Methods This was a population-based household survey conducted from 2020 to 2022, which assessed polio vaccination coverage in children, considering valid, administered, and timely doses by municipality. Results Data were collected from 37,801 children. Vaccination coverage for the complete valid dose schedule was 87.5% (95%CI 86.2;88.7), dropping to 79.6% (95%CI 78.1;81.0), when the booster dose was considered. The dropout rate was 4.5% for the complete schedule, and 11.7% for the first booster. There was no correlation between campaign implementation and high coverage. Conclusion Vaccination coverage for the complete valid dose schedule and the first booster did not meet the 95.0% target. Regional disparities and the association between vaccination coverage and social indicators should be taken into consideration in strategies to increase coverage. 2 capitals District 1 Brazil 201 2018 populationbased population based 202 2022 administered municipality 37801 37 801 37,80 875 87 5 87.5 95%CI 95CI CI 95 86.288.7, 862887 86.2 88.7 , 86 88 7 86.2;88.7) 796 79 6 79.6 78.181.0, 781810 78.1 81.0 78 81 0 78.1;81.0) considered 45 4 4.5 117 11 11.7 950 95.0 target 20 3780 3 80 37,8 8 87. 9 288 86.288.7 86288 862 86. 887 88. 86.2;88.7 79. 181 78.181.0 78181 781 78. 810 81. 78.1;81.0 4. 11. 95. 378 37, 28 86.288. 8628 86.2;88. 18 78.181. 7818 78.1;81. 86.288 86.2;88 78.181 78.1;81 86.28 86.2;8 78.18 78.1;8 86.2; 78.1;

resumen está disponible en el texto completo

https://doi.org/10.1590/s2237-96222024v33e20231303.en

Chronic exertional compartment syndrome
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Duarte, Márcio Luís

; Pereira da Silva, André de Queiroz

; da Silva Xavier, Fernando

; Masson de Almeida Prado, José Luiz

Medicina (Buenos Aires)

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aug 2023, Volume 83 N. 3 Pages 497 - 497

Abstract: En | Text: En | PDF: En

GYPSUM AND POTASSIUM DOSES ON CAULIFLOWER NUTRITIONAL STATUS AND PRODUCTION
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CHARLO, HAMILTON CÉSAR DE OLIVEIRA

; ALMEIDA, JULIANO DA SILVA MARTINS DE

; MOREIRA, ÉDIMO FERNANDO ALVES

; CASTOLDI, RENATA

; LUZ, JOSÉ MAGNO QUEIROZ

; LEMES, ERNANE MIRANDA

Revista Caatinga

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jun 2021, Volume 34 N. 2 Pages 370 - 379

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O gesso é utilizado na agricultura para o fornecimento de nutrientes ao sistema solo-planta, aumento da profundidade do sistema radicular das culturas e, também, para mitigar os efeitos do estresse hídrico nas plantas. No entanto, seu uso indiscriminado pode levar à redução do conteúdo de nutrientes catiônicos da superfície do solo, principalmente o potássio. Assim, o objetivo deste estudo foi avaliar a viabilidade da utilização de gesso, associado à aplicação de potássio, no cultivo de couve-flor, cultivar Sharon. O experimento foi conduzido em esquema fatorial 5×5, sendo avaliadas cinco doses de K (0, 100, 180, 240 e 360 kg ha−1 de K2O) e cinco doses de gesso (0, 500, 1.000, 2.000 e 4.000 kg ha−1) no delineamento em blocos completos casualizados, com três repetições. Foram determinados os teores foliares de N, P, K, Ca, S, Mg, B, Cu, Fe, Mn e Zn e a massa comercial da cabeça, o diâmetro da cabeça, o diâmetro do pedúnculo e a altura da cabeça. A aplicação de 360 kg ha−1 de K2O resultou no aumento de 29,69% no teor foliar de K e 18,94% na massa comercial da cabeça, em relação à dose de 0 kg ha−1 de K2O. A aplicação da dose máxima de gesso, resultou na redução dos teores foliares de enxofre (14,71%) e manganês (25,11%) e, aumento dos teores foliares de cobre (16,97%). Com base nos resultados observados, conclui-se que para a cultura da couve-flor, as doses de gesso e K2O recomendadas são de, respectivamente, 4.000 e 360 kg ha−1.

ABSTRACT Gypsum is widely used in agriculture to supply nutrients to the soil-plant system. However, the excessive use of gypsum may lead to a reduction of cationic soil nutrients such as potassium in the most superficial soil layer. Thus, the objective of this study was to evaluate the feasibility of using gypsum and potassium for cauliflower crop nutritional status and commercial production. The experiment was conducted in 5×5 factorial scheme, corresponding to five K doses (0, 100, 180, 240, 360 kg ha−1 of K2O) and five gypsum doses (0, 500, 1000, 2000, 4000 kg ha−1) in dystrophic Red Latosol. Leaf N, P, K, Ca, Mg, S, B, Cu, Fe, Mn and Zn contents, commercial head mass, diameter and height and peduncle diameter were evaluated. The application of 360 kg ha−1 of K2O resulted in 29.69% more K in cauliflower leaf and 18.94% more commercial head mass compared to the non-application of K. The application of 4000 kg ha−1 of gypsum resulted in reductions of leaf S and Mn and increase in leaf Cu. Based on the results observed, 4000 kg ha−1 of gypsum and 360 kg ha−1 K2O could be required for high cauliflower production.

https://doi.org/10.1590/1983-21252021v34n213rc 106 downloads

Implications for Clinical Practice from a Multicenter Survey of Heart Failure Management Centers
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Bocchi, Edimar Alcides

; Moreira, Henrique Turin

; Nakamuta, Juliana Sanajotti

; Simões, Marcus Vinicius

; Casas, Alberto de Almeida Las

; Costa, Altamiro Reis da

; Assis, Amberson Vieira de

; Durães, André Rodrigues

; Pereira-Barretto, Antonio Carlos

; Ravessa, Antonio Delduque de Araujo

; Macedo, Ariane Vieira Scarlatelli

; Biselli, Bruno

; Pinto, Carolina Maria Nogueira

; Filho, Conrado Roberto Hoffmann

; Costantini, Costantino Roberto

; Almeida, Dirceu Rodrigues

; Santos Jr, Edval Gomes dos

; Soliva Junior, Erwin

; Figueiredo, Estevão Lanna

; Albuquerque, Felipe Neves de

; Paulitsch, Felipe

; Neuenschwander, Fernando Carvalho

; Figueiredo Neto, José Albuquerque de

; Brito, Flavio de Souza

; Lopes, Heno Ferreira

; Villacorta, Humberto

; Souza Neto, João David de

; Sepulveda, João Mariano

; Ayoub, José Carlos Aidar

; Vilela-Martin, José F.

; Cardoso, Juliano Novaes

; Uemura, Laercio

; Moura, Lidia Zytynski

; Maia, Lilia Nigro

; Oliveira, Lucia Brandão de

; Maia, Lucimir

; Silva, Luís Beck da

; Gowdak, Luís Henrique Wolff

; Danzmann, Luiz Claudio

; Andrade, Marcus

; Braile-Sternieri, Maria Christiane Valeria Braga

; Moreira, Maria da Consolação Vieira

; França Neto, Olimpio R

; Filho, Otavio Rizzi Coelho

; Esteves, Paulo Frederico

; Raupp-da-Rosa, Priscila

; Silva, Ricardo Jorge de Queiroz e

; Mourilhe-Rocha, Ricardo

; Viégas, Ruy Felipe Melo

; Rassi, Salvador

; Mangili, Sandrigo

; Kaiser, Sergio Emanuel

; Martins, Silvia Marinho

; Kawabata, Vitor Sergio

Clinics

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2021, Volume 76 elocation e1991

Abstract: En | Text: En | PDF: En

OBJECTIVES: This observational, cross-sectional study based aimed to test whether heart failure (HF)-disease management program (DMP) components are influencing care and clinical decision-making in Brazil. METHODS: The survey respondents were cardiologists recommended by experts in the field and invited to participate in the survey via printed form or email. The survey consisted of 29 questions addressing site demographics, public versus private infrastructure, HF baseline data of patients, clinical management of HF, performance indicators, and perceptions about HF treatment. RESULTS: Data were obtained from 98 centers (58% public and 42% private practice) distributed across Brazil. Public HF-DMPs compared to private HF-DMP were associated with a higher percentage of HF-DMP-dedicated services (79% vs 24%; OR: 12, 95% CI: 94-34), multidisciplinary HF (MHF)-DMP [84% vs 65%; OR: 3; 95% CI: 1-8), HF educational programs (49% vs 18%; OR: 4; 95% CI: 1-2), written instructions before hospital discharge (83% vs 76%; OR: 1; 95% CI: 0-5), rehabilitation (69% vs 39%; OR: 3; 95% CI: 1-9), monitoring (44% vs 29%; OR: 2; 95% CI: 1-5), guideline-directed medical therapy-HF use (94% vs 85%; OR: 3; 95% CI: 0-15), and less B-type natriuretic peptide (BNP) dosage (73% vs 88%; OR: 3; 95% CI: 1-9), and key performance indicators (37% vs 60%; OR: 3; 95% CI: 1-7). In comparison to non- MHF-DMP, MHF-DMP was associated with more educational initiatives (42% vs 6%; OR: 12; 95% CI: 1-97), written instructions (83% vs 68%; OR: 2: 95% CI: 1-7), rehabilitation (69% vs 17%; OR: 11; 95% CI: 3-44), monitoring (47% vs 6%; OR: 14; 95% CI: 2-115), GDMT-HF (92% vs 83%; OR: 3; 95% CI: 0-15). In addition, there were less use of BNP as a biomarker (70% vs 84%; OR: 2; 95% CI: 1-8) and key performance indicators (35% vs 51%; OR: 2; 95% CI: 91,6) in the non-MHF group. Physicians considered changing or introducing new medications mostly when patients were hospitalized or when observing worsening disease and/or symptoms. Adherence to drug treatment and non-drug treatment factors were the greatest medical problems associated with HF treatment. CONCLUSION: HF-DMPs are highly heterogeneous. New strategies for HF care should consider the present study highlights and clinical decision-making processes to improve HF patient care.

https://doi.org/10.6061/clinics/2021/e1991 870 downloads

Effect of aflatoxin B1 on digestibility and blood parameters in horses
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CésarBraga, Auro

; Almeida, Fernando Queiroz de

; Silva, Vinicius Pimentel

; Keller, Kelly Moura

; Maciel, Marina Prado

; Almeida, Maria Izabel Vieira de

; Rosa, Carlos Alberto da Rocha

Ciência Animal Brasileira

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2021, Volume 22 elocation e-63385

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivou-se com esta pesquisa avaliar o efeito da Aflatoxina B1 (AFB1) na digestibilidade dos nutrientes e no perfil hematológico de equinos. O ensaio durou 40 dias, sendo 12 dias para adaptação e 28 dias para experimentação. No período experimental, os cavalos foram distribuídos em delineamento inteiramente casualizado, com três tratamentos, com quatro animais cada. Os tratamentos utilizados foram 0 µg/kg (controle), 50 µg/kg e 100 µg/kg de AFB1 adicionados ao concentrado da dieta basal. A dieta basal continha alimentos naturalmente contaminados com micotoxinas. Um ensaio de digestibilidade foi realizado no final do período experimental, pelo método de coleta parcial de fezes utilizando o LIPE® como indicador. Amostras de sangue foram coletadas uma vez por semana, durante o ensaio para avaliações hematológicas e bioquímicas. Os resultados dos parâmetros hematológicos, bioquímicos e do ensaio de digestibilidade foram submetidos à análise de variância (ANOVA) e comparados pelo teste de Tukey a 5% de significância. As aflatoxinas da dieta aumentaram a contagem de leucócitos, principalmente os neutrófilos maduros. A creatina quinase e a fosfatase alcalina (P<0,05) apresentaram maior atividade nos equinos alimentados com dietas com maior toxicidade. A digestibilidade dos nutrientes não foi alterada pelos níveis de micotoxinas presentes nas dietas (P>0,05).

Abstract This study aimed to evaluate the effect of aflatoxin B1 (AFB1) on the digestibility of nutrients and the hematological profile of horses. The assay lasted 40 days, with 12 days for adaptation and 28 days for experimentation. In the experimental stage, the horses were distributed in a completely randomized design, including three treatment groups with four animals in each group. The treatments used included 0 µg/kg (control), 50 µg/kg, and 100 µg/kg of AFB1 added to a concentrate in the basal diet. The basal diet contained mycotoxins from naturally contaminated feed. A digestibility essay was carried out at the end of the experimental period through partial feces collection, with LIPE® as an indicator. Blood samples were collected once a week during the assay for hematological and biochemical evaluations. The results of the hematological and biochemical parameters were submitted to analysis of variance (ANOVA) and compared by the Tukey test at 5% significance. The aflatoxins in the diet increased the leukocyte count, especially that of mature neutrophils. Creatine kinase and alkaline phosphatase (P < 0.05) activities were higher in horses fed more toxic diets. The digestibility of nutrients was unaffected by the level of mycotoxins in the diet (P > 0.05).

https://doi.org/10.5216/1809-6891v22e-63385 556 downloads

[SciELO Preprints] - O Coração e a COVID-19: O que o Cardiologista Precisa Saber
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Costa, Isabela Bispo Santos da Silva Bittar, Cristina Salvadori Rizk, Stephanie Itala Araújo Filho, Antônio Everaldo de Santos, Karen Alcântara Queiroz Machado, Theuran Inahja Vicente Andrade, Fernanda Thereza de Almeida González, Thalita Barbosa Arévalo, Andrea Nataly Galarza Almeida, Juliano Pinheiro de Bacal, Fernando Oliveira, Gláucia Maria Moraes de Lacerda, Marcus Vinícius Guimarães de Barberato, Silvio Henrique Chagas, Antonio Carlos Palandri Rochitte, Carlos Eduardo Ramires, José Antonio Franchini Kalil Filho, Roberto Hajjar, Ludhmila Abrahão

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Publication date: 2020-05-11

Abstract: Pt

Frente à pandemia da doença causada pelo novo coronavírus (COVID-19), o manejo do paciente com fator de risco e/ou doença cardiovascular é desafiador nos dias de hoje. As complicações cardiovasculares evidenciadas nos pacientes com COVID-19 resultam de vários mecanismos, que vão desde lesão direta pelo vírus até complicações secundárias à resposta inflamatória e trombótica desencadeada pela infecção. O cuidado adequado do paciente com COVID-19 exige atenção ao sistema cardiovascular em busca de melhores desfechos.

[SciELO Preprints] - The Heart and COVID-19: What Cardiologists Need to Know
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Publication date: 2020-05-11

Abstract: En

In face of the pandemic of the novel coronavirus disease 2019 (COVID-19), the management of patients with cardiovascular risk factors and/or disease is challenging. The cardiovascular complications evidenced in patients with COVID-19 derive from several mechanisms, ranging from direct viral injury to complications secondary to the inflammatory and thrombotic responses to the infection. The proper care of patients with COVID-19 requires special attention to the cardiovascular system aimed at better outcomes.

10.

O Coração e a COVID-19: O que o Cardiologista Precisa Saber
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Costa, Isabela Bispo Santos da Silva

; Bittar, Cristina Salvadori

; Rizk, Stephanie Itala

; Araújo Filho, Antônio Everaldo de

; Santos, Karen Alcântara Queiroz

; Machado, Theuran Inahja Vicente

; Andrade, Fernanda Thereza de Almeida

; González, Thalita Barbosa

; Arévalo, Andrea Nataly Galarza

; Almeida, Juliano Pinheiro de

; Bacal, Fernando

; Oliveira, Gláucia Maria Moraes de

; Lacerda, Marcus Vinícius Guimarães de

; Barberato, Silvio Henrique

; Chagas, Antonio Carlos Palandri

; Rochitte, Carlos Eduardo

; Ramires, José Antonio Franchini

; Kalil Filho, Roberto

; Hajjar, Ludhmila Abrahão

Arquivos Brasileiros de Cardiologia

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may 2020, Volume 114 N. 5 Pages 805 - 816

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Frente à pandemia da doença causada pelo novo coronavírus (COVID-19), o manejo do paciente com fator de risco e/ou doença cardiovascular é desafiador nos dias de hoje. As complicações cardiovasculares evidenciadas nos pacientes com COVID-19 resultam de vários mecanismos, que vão desde lesão direta pelo vírus até complicações secundárias à resposta inflamatória e trombótica desencadeada pela infecção. O cuidado adequado do paciente com COVID-19 exige atenção ao sistema cardiovascular em busca de melhores desfechos.

Abstract In face of the pandemic of the novel coronavirus disease 2019 (COVID-19), the management of patients with cardiovascular risk factors and/or disease is challenging. The cardiovascular complications evidenced in patients with COVID-19 derive from several mechanisms, ranging from direct viral injury to complications secondary to the inflammatory and thrombotic responses to the infection. The proper care of patients with COVID-19 requires special attention to the cardiovascular system aimed at better outcomes.

https://doi.org/10.36660/abc.20200279 35382 downloads

11.

Biochar in sugar beet production and nutrition
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Zelaya, Katherin Prissila Sevilla

; Alves, Barbara Samartini Queiroz

; Colen, Fernando

; Frazão, Leidivan Almeida

; Sampaio, Regynaldo Arruda

; Pegoraro, Rodinei Facco

; Fernandes, Luiz Arnaldo

Ciência Rural

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2019, Volume 49 N. 5 elocation e20180684

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: O processo de pirólise da biomassa pode ser uma alternativa para o uso agrícola de lodo de esgoto. Este trabalho objetivou avaliar o uso de biochar produzido a partir da mistura de lodo de esgoto e bagaço de cana (BB, 1:1 relação lodo de esgoto e e bagaço de cana) na produção e nutrição de beterraba (Beta vulgaris L.). Conduziu-se um experimento em casa de vegetação com cinco dose de BB: 0, 2,5, 5, 7,5 e 10% v/v, e dois tratamentos adicionais, biochar de lodo de esgoto (BS, 5% v/v) e tratamento convencional (CV) com calagem e fertilizantes minerais. Após 45 dias de incubação dos solos tratados, cultivou-se as plantas por 55 dias. O biochar produzido a partir de lodo de esgoto e bagaço de cana-de-açúcar é uma tecnologia alternativa para reduzir o potencial de contaminação do lodo de esgoto e incorporar formas mais estáveis de carbono ao solo. Embora o biochar tenha aumentado à fertilidade do solo, as raízes finas e a eficiência de absorção de nutrientes pelas plantas de beterraba, a produção de matéria seca total foi significativamente menor que a obtida no tratamento convencional.

ABSTRACT: The biomass pyrolysis process may be an alternative for the agricultural use of sewage sludge. This study aimed to evaluate the use of of biochars from mixture of sewage sludge and sugarcane bagasse (BB, 1:1 relationship sewage sludge and sugarcane bagasse) on sugar beet (Beta vulgaris L.) production and nutrition. A greenhouse experiment was conducted with five application rates of BB: 0, 2.5, 5, 7.5, and 10% (v/v), and two additional treatments, biochar from sewage sludge (BS, application rate 5% (v/v)) and conventional treatment (CV) that received lime and mineral fertilizer. The treated soils were incubated for 45 days, after which, seedlings were cultivated for 55 days. Biochar produce from sewage sludge and sugarcane bagasse is an alternative technology to reduce the potential for contamination of sewage sludge and to incorporate more stable carbon forms in the soil. Although, biochar has increased soil fertility, fine roots and nutrient uptake efficiency by sugar beet plants, total dry matter yield was significantly lower than that obtained in conventional treatment.

https://doi.org/10.1590/0103-8478cr20180684 2140 downloads

12.

Incorporation of compound inflorescences and selection of high-yielding progenies in cowpea
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Bernardo, Karla Annielle da Silva

; Freire Filho, Francisco Rodrigues

; Ribeiro, Valdenir Queiroz

; Vieira, Paulo Fernando de Melo Jorge

; Lopes, Ângela Celis de Almeida

; Oliveira, Rosana Mendes de Moura

Pesquisa Agropecuária Brasileira

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oct 2018, Volume 53 N. 10 Pages 1150 - 1157

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo: O objetivo deste trabalho foi obter progênies de feijão-caupi (Vigna unguiculata) com inflorescência composta, pedúnculo curto, ciclo precoce, boa arquitetura de planta e alto potencial produtivo. O material genético inicial constituiu-se de 453 progênies F2:3, selecionadas a partir de dez cruzamentos e avaliadas em delineamento de blocos aumentados de Federer, com duas testemunhas. Dessas, selecionaram-se 60 progênies das gerações F4:5 e F4:6, que foram analisadas em dois experimentos sucessivos, ambos em delineamento látice 8x8, com quatro testemunhas e quatro repetições. A seleção precoce foi eficiente para fixação dos caracteres avaliados. Detectou-se ampla variabilidade genética entre e dentro das progênies. As herdabilidades e os ganhos genéticos estimados e realizados nas progênies F4:5 e F4:6 indicam a possibilidade de seleção de progênies precoces, com comprimento de pedúnculo curto, inflorescência composta e produtividade igual ou superior à das cultivares comerciais utilizadas como testemunhas.

Abstract: The objective of this work was to obtain cowpea (Vigna unguiculata) progenies with compound inflorescences, short peduncles, early cycle, good plant architecture, and high-yielding potential. The initial genetic material consisted of 453 F2:3 progenies, selected from ten crosses and evaluated using Federer’s augmented block design, with two controls. Of these, 60 progenies from the F4:5 and F4:6 generations were selected and assessed in two consecutive experiments, both in a 8x8 lattice design with four controls and four replicates. Early selection was efficient at fixing the evaluated traits. A wide genetic variability was detected among and within progenies. The estimated and obtained heritability and genetic gains in the F4:5 and F4:6 progenies indicate the possibility of selection of early progenies with short peduncles, compound inflorescences, and productivity similar to or greater than that of the commercial cultivars used as controls.

https://doi.org/10.1590/s0100-204x2018001000008 441 downloads

13.

Equine fecal inoculum optimization in in vitro fermentation assays of dehydrated roughage
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Franzan, Bruna Caroline

; Franco, Tatiana Werneck

; Stefani, Giselle

; Pereira, Marcelo Maia

; Almeida, Fernando Queiroz de

; Silva, Vinicius Pimentel

Revista Brasileira de Zootecnia

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2018, Volume 47 elocation e20180006

Abstract: En | Text: En | PDF: En

ABSTRACT This study evaluated the influence of coastcross hay substrate hydration and equine fecal inoculum dilution on the parameters of fermentation and microbiology in in vitro essays. A 2 × 2 factorial block design was used. The first factor was hydration of the coastcross hay substrate 12 h before incubation or at the time of incubation, and the second factor was the dilution of fecal inoculum with a nutrient solution in a weight: weight ratio of 1:1 or 1:3. Degradation of the dry matter (DM), organic matter (OM), and neutral detergent fiber (NDF) were evaluated at 24, 48, and 72 h. Microorganisms were counted 24 h after inoculation. The ammoniacal nitrogen concentration (NH3-N), pH, and cumulative gas production were measured up to 72 h and adjusted by the non-linear Gompertz regression model. Hydration of substrate and time of incubation increased nutrient degradation of coastcross hay, as well as the final volume of gases and the concentration of Streptococcus spp. The 1:3 dilution increased the final pH and Streptococcus spp. concentration. The hydration of substrate did not have any effect on NH3-N, Lactobacillus spp., cellulolytic, and total anaerobic bacteria concentrations. In addition, no effect of hydration was observed on the fermentation rate and the maximum fermentation time on the model used. The fermentation profile of the grass substrate is not affected by dilution, and, therefore, horse feces can be used as a source of inoculum in in vitro fermentation trials. Hydration increases the gas volumes and the nutrient degradation of grass hay, renders the lag phase time insignificant and, therefore, can be irrelevant in terms of fermentation model settings.

https://doi.org/10.1590/rbz4720180006 836 downloads

14.

Development of Mangalarga Marchador suckling foals supplemented with fructooligosaccharides
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Dias, Ana Carla Chaves

; Cabral, Grasiele Coelho

; Ferreira e Silva, Camila

; Ferreira, Marcelle Christine Nascimento

; Franco, Tatiana Werneck

; Moura, Raiane Araújo

; Silva, Vinícius Pimentel

; Almeida, Fernando Queiroz de

Revista Brasileira de Zootecnia

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sep 2017, Volume 46 N. 9 Pages 747 - 754

Abstract: En | Text: En | PDF: En

ABSTRACT The objective of this study was to evaluate the effect of prebiotic fructooligosaccharide (FOS) supplementation on the development of Mangalarga Marchador suckling foals. Sixteen Mangalarga Marchador foals, from birth to 75 days of age, were evaluated in a completely randomized design, with two treatments (experimental group and control group) with eight repetitions (animals). The foals were evaluated through body weight, morphometric, and circumferential measures. The daily, weekly, and cumulative weight gains were recorded and the morphometric measures were: withers height, croup height, body length, mid-back height, mid-back width, and thorax, shin, knee, and forearm circumferences. The mean body weight was 32.3 and 77.9 kg at birth and 75 days of age, respectively. The mean withers height was 86 and 103.8 cm at birth and 75 days of age, respectively, and the mean body length was 63.9 cm at birth, reaching 89.1 cm at 75 days of age. No significant differences in the FOS supplementation or interaction of age versus supplementation between the experimental and control groups were observed for any of the parameters evaluated. However, there were significant differences between the ages. Supplementation with prebiotic FOS does not affect the development of the Mangalarga Marchador suckling foals from birth to 75 days of age.

https://doi.org/10.1590/s1806-92902017000900006 1066 downloads

15.

Blood biochemical parameters of Brazilian sport horses under training in tropical climate
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Padilha, Felipe Gomes Ferreira

; Dimache, Luana Avila Giorgia

; Almeida, Fernando Queiroz de

; Ferreira, Ana Maria Reis

Revista Brasileira de Zootecnia

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aug 2017, Volume 46 N. 8 Pages 678 - 682

Abstract: En | Text: En | PDF: En

ABSTRACT This study aimed to provide baseline data for the serum biochemical parameters of Brazilian sport horses undergoing physical training for eventing to be used as a practical guide. A total of 139 blood samples were collected by vacuum venipuncture of the jugular vein from healthy horses in training. Tubes without anticoagulant were used for biochemical analysis. Means and standard deviations were determined for aspartate aminotransferase (AST) (306.27±84.66 U/L), creatine kinase (CK) (181.06±80.38 U/L), urea (29.51±5.82 mg/dL), creatinine (1.44±0.20 mg/dL), gamma glutamyl transferase (GGT) (14.58±6.55 U/L), calcium (13.22±0.59 mg/dL), and albumin (2.86±0.16 g/dL). The specific reference ranges were: AST, 197-454 U/L; CK, 116-290 U/L; urea, 22-42 mg/dL; creatinine, 1.2-1.8 mg/dL; GGT, 9-26 U/L; calcium, 12.2-14.2 mg/dL; and albumin, 2.6-3.1 g/dL. Beneficial effects of the training program on the horses were observed and these effects did not lead to any changes in the biochemical parameters studied. The environment may influence the serum biochemical parameters, particularly AST and CK, of Brazilian sport horses.

https://doi.org/10.1590/s1806-92902017000800008 2000 downloads

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