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Abstract Objectives: To evaluate the impact of cholecalciferol (D₃ ) supplementation using clinical and paraclinical variables in patients with RA and vitamin D insufficiency and deficiency. Methods: A randomized, double-blind, placebo-controlled study included patients from 5 to 40 years with a diagnosis of RA and vitamin D insufficiency and deficiency. They were supplemented for 8 weeks with 4000 or levels at baseline and at the end of the study. Results: A total of 31 patients were included, with a mean age of 18.19 years. In the active group, there was a significant improvement in symptomatology with respect to the TNSS score and an increase in serum vitamin D levels (p < 0.01). There were no adverse reactions with cholecalciferol or placebo. Conclusions: Supplementing patients with vitamin D₃ , at the evaluated dose, together with conventional treatment for allergic rhinitis results in symptoms and quality of life improvement in patients with this disease.

Resumen Objetivos: Evaluar el impacto de la suplementación con colecalciferol (D₃) mediante variables clínicas y para clínicas en pacientes con RA e insuficiencia y deficiencia de vitamina D. Métodos: Estudio aleatorio, doble ciego, placebo controlado, en el que se incluyeron pacientes de 5 a 40 años, con diagnóstico de RA e insuficiencia y deficiencia de vitamina D. Fueron suplementados con 4000 o 5000 UI,dependiendo de la edad, durante 8 semanas. Mensualmente se midió la puntuación total síntomas nasales (TNSS) y las concentraciones de 25(OH)D₃ al inicio y al final del estudio. Resultados: Se incluyeron 31 pacientes, con una edad promedio de 18.19 años. En el grupo activo existió una mejoría significativa en la sintomatología respecto a la puntación de TNSS y un incremento en los niveles séricos de vitamina D (p < 0.01). No se presentaron reacciones adversas con la ingesta de colecalciferol o placebo. Conclusiones: Suplementar a los pacientes con vitamina D₃ , a la dosis evaluada, junto con el tratamiento convencional para la rinitis alergica resulta en una mejoría sintomática y en la calidad de vida de los pacientes con esta enfermedad.

https://doi.org/10.29262/ram.v71i2.1282

Intervención educativa sobre cáncer bucal y su prevención en estudiantes preuniversitarios
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Álvarez Hernández, José Carlos

; Quintana Morales, Eniley

; Guzmán López, Ailen

; León Palombí, Marino Enrique

; Morales Cabrera, Marileidi

; Morales Pardo, Mara Isabel

MediSur

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feb 2024, Volume 22 N. 1 Pages 38 - 47

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN Fundamento el aumento de la incidencia del cáncer bucal constituye un problema de salud mundial, por ello surge la necesidad de realizar acciones educativas que tributen a la prevención de la enfermedad desde edades tempranas. Objetivo evaluar la efectividad de una intervención educativa sobre cáncer bucal y su prevención en estudiantes de un centro preuniversitario. Métodos se realizó un estudio preexperimental, de intervención educativa, con diseño preprueba/posprueba, en el periodo comprendido entre noviembre de 2021 a mayo de 2022. Se trabajó con la totalidad del universo, el cual estuvo constituido por 125 estudiantes de la escuela Roberto Rodríguez, del municipio Morón, Ciego de Ávila. Se utilizó estadística descriptiva e inferencial. Resultados el 52,0 % de los participantes perteneció al sexo femenino. La media de edad para ambos sexos fue de 15,86 ± 1,053 años. El 36,8 % cursaba el onceno grado. Se determinaron inadecuados niveles de información en la etapa diagnóstica en cuanto a: generalidades (96,0 %), factores de riesgo (91,2 %), autoexamen bucal (96,0 %) y medidas de promoción y prevención (95,2 %). Después de aplicada la intervención se logró elevar el nivel cognoscitivo hasta un 97,6 %, 99,2 %, 96,8 % y 99,2 % respectivamente. El test de McNemar arrojó resultados significativos (p = 0,000; p < 0,05). Conclusiones se logró una modificación estadísticamente significativa de la información en cada uno de los encuestados, por lo que se pudo inferir que la intervención educativa resultó efectiva.

ABSTRACT Foundation the increase in the incidence of oral cancer constitutes a global health problem, there is a need to carry out educational actions that contribute to the prevention of the disease from an early age. Objective to evaluate the effectiveness of an educational intervention on oral cancer and its prevention in students from a pre-university center. Methods a pre-experimental educational intervention study was carried out, with a pre-test/post-test design, from November 2021 to May 2022. The entire universe was studied, 125 students from the Roberto Rodríguez School in Morón municipality, Ciego de Ávila. Descriptive and inferential statistics were used. Results 52.0% of the participants were female. The mean age for both sexes was 15.86 ± 1.053 years. 36.8% were in eleventh grade. Inadequate levels of information were determined in the diagnostic stage in terms of: generalities (96.0%), risk factors (91.2%), oral self-examination (96.0%) and promotion and prevention measures (95.2%). %). After applying the intervention, the cognitive level was raised to 97.6%, 99.2%, 96.8% and 99.2% respectively. The McNemar test showed significant results (p = 0.000; p < 0.05). Conclusions a statistically significant modification of the information was achieved in each of the respondents, so it could be inferred that the educational intervention was effective.

La Formación Didáctica Continua en la preparación a los docentes de la especialidad Maestro Primario
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Torres Cardoso, Carlos Luis

; Companioni Álvarez, Inés

; Aliaga López, Marisbel

Conrado

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feb 2024, Volume 20 N. 96 Pages 8 - 14

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN Los docentes de las escuelas pedagógicas de la especialidad Maestro Primario que imparten las asignaturas de las Didácticas Particulares, necesitan prepararse sistemáticamente para desarrollar la habilidad profesional pedagógica dirigir el proceso educativo en general y el de enseñanza-aprendizaje en particular, por lo que conciben la práctica laboral de cada año en una secuencia lógica, sistémica y como nodo interdisciplinario. La preparación se enmarca en el Consejo Técnico a nueve docentes responsables de asignaturas. Dada la insuficiente formación didáctica que poseen, porque proceden de diversos planes y modalidades de titulación, se potencian los objetivos gradados desde el primer al cuarto año de la especialidad. El contenido se sistematiza con el empleo de métodos del nivel teórico. Es propósito de este artículo ofrecer las consideraciones que sustentan la definición de formación didáctica continua, los requerimientos de la misma, la concepción de la práctica laboral de los estudiantes de las escuelas pedagógicas como nodo interdisciplinario y las potencialidades del trabajo metodológico a través del Consejo Técnico y las visitas a clases a los docentes de las escuelas pedagógicas de la especialidad Maestro Primario.

ABSTRACT The teachers of the pedagogical schools of the Primary Teacher specialty that teach the subjects of the Private Didactics, need to be systematically prepared to develop the pedagogical professional ability to direct the educational process in general and the teaching-learning process in particular, for which they conceive the practice work of each year in a logical, systemic sequence and as an interdisciplinary node. The preparation is part of the Technical Council to nine teachers responsible for subjects. Given the insufficient didactic training that they have, because they come from different plans and modalities of degree, the graduated objectives are promoted from the first to the fourth year of the specialty. The content is systematized with the use of theoretical level methods. It is the purpose of this article to offer the considerations that support the definition of continuous didactic training, its requirements, the conception of the work practice of students of pedagogical schools as an interdisciplinary node and the potential of methodological work through the Technical Council and class visits to teachers of the pedagogical schools of the Primary Teacher specialty.

Perseguir al anarquista. La División de Investigaciones de la Policía de Rosario y su inscripción en la trama internacional: un estudio de caso a partir de la huelga de estibadores de 1906
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López Calvino, Nicolás

; Álvarez, Carlos Alberto

Avances del Cesor

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dec 2023, Volume 20 N. 29 Pages 1 - 1

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract The aim of this paper is to explain the problem of how the Investigations Division of the Rosario Police constructed the profile of dangerous subjects in the context of the international fight against anarchism, based on the case study of the dockworkers' strike of October 1906. The sources used are the police records, a technology that was systematically put into circulation for the first time in the context of that strike. We argue that the police prioritized the identification of anarchist militancy, understood as the archetype of the dangerous subject. On the other hand, we affirm that the workers rehearsed repertoires of coordinated protest against the police arrests and interrogations to which they were subjected. This paper seeks to contribute to the experience of Rosario in terms of the transnational dynamics of the struggle against anarchism.

Resumen El presente trabajo tiene como objetivo explicar el problema de la conformación del perfil de los sujetos peligrosos por parte de la División de Investigaciones de la Policía de Rosario, en el marco del combate internacional al anarquismo, a partir del estudio de caso de la huelga de estibadores portuarios de octubre de 1906. Se utiliza como fuentes los prontuarios policiales, tecnología puesta en circulación de forma sistemática por primera vez en el marco de aquella huelga. Sostenemos que dicha policía priorizó la identificación de la militancia anarquista, entendida como arquetipo del sujeto peligroso. Por otra parte, afirmamos que los obreros ensayaron repertorios de contestación coordinados ante las detenciones policiales y los interrogatorios a que fueron sometidos. El trabajo busca aportar la experiencia rosarina en torno a la dinámica trasnacional de lucha contra el anarquismo.

https://doi.org/10.35305/ac.v20i29.1880

Remediación de suelos contaminados con hidrocarburos empleando sustancias húmicas de vermicomposta
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Ojed4a-Morales, Marcia E.

; Córdova-Bautista, Yolanda

; Álvarez-Ramírez, Juan G.

; López-Lázaro, José de los S.

; Martínez-Pereyra, Gabriel

; Morales-Bautista, Carlos M.

Terra Latinoamericana

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dec 2023, Volume 41 elocation e1656

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Summary: Bioremediation with humic substances is one of the recent and promising techniques for the restoration of soils contaminated by hydrocarbons, but little information is available on its behavior in different types of soil. For these reasons, this research aimed to evaluate the removal of total petroleum hydrocarbons (HTP) in three types of soil with different textures (S1, S2 and S3) and treated with organic vermicompost amendments (cocoa husks, Theobroma cacao; rice, Oriza sativa; sugarcane bagasse, Saccharum officinarum; cow manure) and commercial humic substances (potassium humate). A randomized multifactorial experimental design (3 × 3 × 2) was proposed, which consisted of the type of soil, organic amendment (without vermicompost, with organic vermicompost, commercial humic substances) and microbial load (with microorganisms, without microorganisms). The results were analyzed using the ANOVA-Tukey tests in the Statgraphics CenturionTM V.18 program (α = 0.05) in order to evaluate significant differences between treatments. The results show that S2 with the addition of organic matter had the highest removal (86% of HTP) after 60 days of incubation, compared to the treatment with commercial humic substances, which are related to the low bioavailability of the microorganisms. This behavior was also observed in S3 with a TPH percentage removal of 77.52 and 63.4% for S1. Finally, the cell growth rate was better in S2 with commercial humic substances. An average growth of 94 × 104 CFU g-1 of soil was obtained during the 60 days of evaluation of the experiment, and a maximum of 98×105 CFU g-1 of soil in the 45 days of treatment. To conclude, the use of vermicompost is adequate for clayey soils, since the degradation rates are higher in them. In addition, they represent a cheaper alternative to synthetic treatments and revaluation of organic waste.

Resumen: La biorremediación utilizando sustancias húmicas es una de las técnicas recientes y prometedoras para la restauración de suelos contaminados por hidrocarburos, pero existe poca información sobre su comportamiento en los diversos tipos de suelo. Por estas razones, esta investigación tuvo como objetivo evaluar la remoción de hidrocarburos totales del petróleo o HTP en tres suelos con diferentes texturas (S1, S2 y S3) y tratados con enmiendas orgánicas de vermicomposta (cascarillas de cacao, Theobroma cacao; arroz, Oriza sativa; bagazo de caña, Saccharum officinarum; estiércol de vaca) y sustancias húmicas comerciales (humato de potasio). Se planteó un diseño experimental multifactorial aleatorio (3 × 3 × 2), constituido por tipo de suelo, enmienda orgánica (sin vermicomposta, con vermicomposta orgánica, con sustancias húmicas comerciales), y carga microbiana (con microorganismos, sin microorganismos). Los resultados fueron analizados mediante las pruebas ANOVA-Tukey en el programa Statgraphics Centurion TM V.18 (α = 0.05) con el fin de evaluar diferencias significativas entre los tratamientos. Los resultados muestran que S2 con vermicomposta orgánica tuvo la mayor remoción (86% de HTP) luego de 60 días de incubación, en comparación con el tratamiento con sustancias húmicas comerciales, relacionándose con la baja biodisponibilidad de microorganismos. Este comportamiento también se observó en S3, el cual tuvo un porcentaje de remoción de HTP de 77.52 y 63.4%. Finalmente, la tasa de crecimiento celular fue mejor en S2 con sustancias húmicas comerciales. Se obtuvo un crecimiento promedio de 94×104 UFC g-1 de suelo durante los 60 días de evaluación del experimento, y un máximo de 98×105 UFC g-1 de suelo a los 45 días de tratamiento. Se concluye que el uso de vermicomposta es adecuada para suelos arcillosos, ya que las tasas de degradación son mayores en ellos. Además, representan una alternativa de menor costo que los tratamientos sintéticos y de revalorización de residuos orgánicos.

https://doi.org/10.28940/terra.v41i0.1656

Wheat or maize silage in feeding strategies for cows in small-scale dairy systems during the dry season
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Álvarez-García, Cloe D.

; Arriaga-Jordán, Carlos M.

; Estrada-Flores, Julieta G.

; López-González, Felipe

Chilean journal of agricultural research

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aug 2023, Volume 83 N. 4 Pages 398 - 407

Abstract: En | Text: En | PDF: En

ABSTRACT The conservation of forage as silage allows its application during the dry season in dairy cattle feeding. The most commonly used forage for this purpose is maize (Zea mays L.), but due to the possible effects of climate change, the diversification of crops with shorter agronomic cycles as wheat (Triticum aestivum L.) should be considered. Therefore, the objective was to evaluate the chemical composition of silages, the productive response of dairy cows fed wheat and maize silage, as well as their feeding costs. Three treatments were evaluated with 9.8 kg DM cow-1 d-1 silage plus 4.6 kg DM cow-1 d-1 commercial concentrate each. Treatments were 100% wheat silage (WS), 50% wheat silage-50% maize silage (WMS), and 100% maize silage (MS). Six Holstein cows were used in groups of three randomly assigned to treatment sequence in a 3×3 Latin square design repeated twice. There were significant differences (P < 0.05) between treatments in silage chemical composition, except in NDF and ADF (P > 0.05). There were nonsignificant differences in animal variables (P > 0.05) with mean milk yield of 15.4 kg cow-1 d-1, 33.7 g kg-1 milkfat, 30.5 g kg-1 milk protein, 481.2 kg live weight and 2.1 body condition score. There were significant differences (P < 0.05) in silage and total DM intake in the third experimental period (three periods, 14 d each one) with 8.1 and 12.7 kg DM cow-1 d-1, respectively. Although cost for wheat silage were higher than maize silage, all three treatments showed positive margins on feeding costs.

Evaluación de aditivos y etapa fenológica sobre el valor nutricional de ensilado de Tithonia tubiformis
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Álvarez-García, Cloe Dafne

; Sánchez-Valdés, Jair Jesús

; Pozo-Leyva, Dixan

; Arriaga-Jordán, Carlos Manuel

; López-González, Felipe

Ecosistemas y recursos agropecuarios

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aug 2023, Volume 10 N. 2 elocation e3383

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen El objetivo fue evaluar ensilado de Tithonia tubiformis con diferentes aditivos para determinar composición química, parámetros de fermentación ruminal y de producción de gas in vitro. Se evaluaron dos etapas fenológicas (floración y reproductiva) y tres tratamientos de aditivos; control (CTR), melaza (MLZ) y bacterias ácido lácticas (BAL), mediante un diseño experimental factorial 3x2. Las variables evaluadas fueron materia seca (MS), materia orgánica (MO), proteína cruda (PC), fibra detergente neutro (FDN), fibra detergente acido (FDA), energía metabolizable estimada (eEM), digestibilidad in vitro de la MS (DIVMS), MO (DIVMO) y de la FDN (DIVFDN) y producción de gas in vitro. Se presentaron diferencias (P < 0.05) en las variables de composición química, digestibilidad in vitro, eEM y parámetros de cinética de fermentación entre tratamientos a excepción de FDA, DIVFDN, C1, B, C2 y lag, para etapas fenológicas se presentaron diferencias (P < 0.05) en todas las variables a excepción de FDN, FDA, A y C1.

Abstract The objective was to evaluate Tithonia tubiformis silage with different additives to determine its chemical composition, ruminal fer mentation parameters and in vitro gas production, two phenological stages (flowering and reproductive) and three additive treatments for the silages were evaluated; control (CTR), molasses (MLZ) and lactic acid bacteria (BAL), through an analysis of variance with a 3x2 factorial experimental design. The variables evaluated were dry matter (DM), organic matter (OM), crude protein (CP), neutral detergent fiber (NDF), acid detergent fiber (ADF), estimated metabolizable energy (eEM), in vitro digestibility of DM (IVDDM), MO (IVDOM) and NDF (IVDNDF), as well as in vitro gas production. Differences (P < 0.05) were found in the chemical composition, in vitro digestibility, eEM and parameters of fermentation kinetics variables between treatments, except for ADF, IVNDF, C1, B, C2 and lag, regarding phenological stages there were differences (P < 0.05) in all variables except for NDF, ADF, A and C1.

https://doi.org/10.19136/era.a10n2.3383

Guía de práctica clínica para el manejo del cáncer de pulmón de células pequeñas: enfermedad extensa
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Cabrera-Miranda, Luis A.

; Díaz-García, Diego A.

; Corona-Cruz, José F.

; Lozano-Ruiz, Francisco J.

; Sánchez-Reyes, Roberto

; Álvarez-Bojórquez, Mario E.

; Blake-Cerda, Mónika

; Rivera-Márquez, Raúl

; López-Saucedo, Raúl A.

; Pérez-Álvarez, Sandra I.

; Bolaño-Guerra, Laura M.

; Alatorre-Alexander, Jorge A.

; Alexander-Meza, Francisco

; Barrón-Barrón, Feliciano

; Blanco-Vázquez, Yazmín C.

; Campos-Gómez, Saúl

; Mata-Moya, Dolores de la

; Figueroa-Martínez, Pedro

; González-Cisneros, Paulina E.

; Íñiguez-García, Marco A.

; Lázaro-León, Jesús M.

; Loyola-García, Ulises

; Morales-Rivera, Marcelino

; Olivares-Torres, Carlos

; Ramos-Ramírez, Maritza

; Sáenz-Frías, Julia A.

; Silva-Bravo, Fernando

; Trejo-Rosales, Rogelio

; Souto-del Bosque, Miguel

; Arrieta, Óscar

Gaceta mexicana de oncología

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jun 2023, Volume 22 N. 2 Pages 55 - 73

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Antecedentes: El cáncer de células pequeñas (CPCP) representa el 13-15% del total de neoplasias primarias de pulmón. Se caracteriza por su rapidez en la tasa de crecimiento y en el desarrollo de metástasis a distancia. Objetivos: Orientar y estandarizar el tratamiento del CPCP enfermedad extensa en México basado en evidencia clínica nacional e internacional. Material y métodos: Este documento se desarrolló como una colaboración del Instituto Nacional de Cancerología y la Sociedad Mexicana de Oncología en cumplimiento con estándares internacionales. Se integró un grupo conformado por oncólogos médicos, cirujanos oncólogos, cirujanos de tórax, radio-oncólogos y metodólogos con experiencia en revisiones sistemáticas de la literatura y guías de práctica clínica. Resultados: Se consensaron, por el método Delphi y en reuniones a distancia, las recomendaciones en CPCP enfermedad extensa, producto de preguntas de trabajo. Se identificó y evaluó la evidencia científica que responde a cada una de dichas preguntas clínicas antes de incorporarla al cuerpo de la guía. Conclusión: Esta guía proporciona recomendaciones clínicas para el manejo de la enfermedad extensa del CPCP y durante el proceso de toma de decisiones de los clínicos involucrados con su manejo en nuestro país para mejorar la calidad de la atención clínica para estos pacientes.

Abstract Background: Small cell lung cancer (SCLC) represents 13-15% of all primary lung neoplasms and is characterized by its rapid growth rate and the rapid development of distant metastases. Objectives: To guide and standardize the treatment of extensive disease small cell lung cancer in Mexico based on national and international clinical evidence. Material and methods: This document was developed as a collaboration between the National Cancer Institute and the Mexican Society of Oncology in compliance with international standards. An interdisciplinary group was formed, including medical oncologists, oncological surgeons, thoracic surgeons, radiation oncologists, and methodologists with experience in systematic reviews of the literature and clinical practice guidelines. Results: A consensus was reached, both by the Delphi method and in remote meetings, of extensive disease recommendations resulting from work questions. The scientific evidence that answers each of these clinical questions was identified and critically evaluated, before being incorporated into the body of evidence of the Guide. Conclusions: This Clinical Practice Guide provides clinical recommendations for the management of extensive disease of SCLC to contribute to the decision-making process of the clinicians involved with its management in our country, hoping that this will contribute to improving the quality of clinical care in these patients.

https://doi.org/10.24875/j.gamo.22000122

Influence of temperature on respiratory metabolism during early development of Totoaba macdonaldi
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Larios-Soriano, Ernesto

; Díaz, Fernando

; Re-Araujo, Ana Denise

; López, Lus M.

; López-Galindo, Laura

; True, Conal D.

; Álvarez, Carlos A.

; Galaviz, Mario A.

Latin american journal of aquatic research

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mar 2023, Volume 51 N. 1 Pages 109 - 116

Abstract: En | Text: En | PDF: En

ABSTRACT Environmental temperature can act as a positive or negative modulator of the physiology and metabolism of poikilothermic organisms. As a general rule, larvae and juveniles are more sensitive to temperature stress than adults, which represents a key factor that partly determines their development and growth in aquaculture. Therefore, this study analyzed the effect of exposure to temperatures of 21, 24, and 27°C on the respiratory metabolism (RM) of Totoaba macdonaldi in different developmental stages. For this purpose, eggs, larvae with 4, 6, 8, 14, and 22 days post-hatch (dph), and juveniles of 25 dph were exposed to the experimental temperatures for 5 h. After the exposure time, oxygen consumption measurements were performed. The results clearly show that temperature (21 to 27°C) has the greatest effect on RM in eggs and larvae at 4 and 22 dph (3.1 ± 0.3 to 4.3 ± 0.3 µmol O2 h−1 egg−1, 2.9 ± 0.3 to 10.5 ± 1.2 µmol O2 h−1 larvae−1 and 102.0 ± 6.4 to 189.8 ± 15.3 µmol O2 h−1 larvae−1, respectively). This thermal sensitivity was not observed from 6, 8, and 14 dph larvae and juveniles at 25 dph, where morphological development was the main factor that influencing the RM. Therefore, this study shows that temperature affects RM in different development stages of totoaba, beginning in the egg stage and intensifying once the larvae hatch until 22 dph. Understanding how temperature affects energy expenditure by measuring RM is essential to establish culture conditions that allow better physiological performance and growth in the early life stages of T. macdonaldi.

https://doi.org/10.3856/vol51-issue1-fulltext-2952

10.

Guía de práctica clínica para el manejo del cáncer de pulmón de células pequeñas: enfermedad limitada
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Cabrera-Miranda, Luis A.

; Lozano-Ruiz, Francisco J.

; Blake-Cerda, Mónika

; Corona-Cruz, José F.

; Sánchez-Reyes, Roberto

; Pérez-Álvarez, Sandra I.

; Díaz-García, Diego A.

; Álvarez-Bojórquez, Mario E.

; Rivera-Márquez, Raúl

; López-Saucedo, Raúl A.

; Bolaño-Guerra, Laura M.

; Maldonado-Magos, Federico

; Aldaco-Sarvide, Fernando

; Alvarado-Zermeño, Adriana

; Barajas-Figueroa, Luis J.

; Bautista-Aragón, Yolanda

; Bolaños-Morales, Francina V.

; Castillo-Ortega, Graciano

; Félix-Leyva, Jesús A.

; Gerson-Cwilich, Raquel

; Guzmán-de Alba, Enrique

; López-Galindo, Ángel A.

; Mariscal-Ramírez, Carlos

; Piñeiro-Retif, Rafael

; Ramos-Prudencio, Rubí

; Rodríguez-Cid, Jerónimo

; Silva-Bravo, Fernando

; Arrieta, Óscar

Gaceta mexicana de oncología

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mar 2023, Volume 22 N. 1 Pages 3 - 23

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Antecedentes: El cáncer de células pequeñas (CPCP) representa el 13-15% del total de neoplasias primarias de pulmón. Se caracteriza por su rapidez en la tasa de crecimiento y en el desarrollo de metástasis a distancia. Objetivos: Orientar y estandarizar el tratamiento del CPCP, enfermedad limitada, en México, basado en evidencia clínica nacional e internacional. Material y métodos: Este documento se desarrolló como una colaboración entre el Instituto Nacional de Cancerología y la Sociedad Mexicana de Oncología en cumplimiento con estándares internacionales. Se integró un grupo conformado por oncólogos médicos, cirujanos oncólogos, cirujanos de tórax, radio-oncólogos y metodólogos con experiencia en revisiones sistemáticas de la literatura y guías de práctica clínica. Resultados: Se consensuaron, por el método Delphi y en reuniones a distancia, las recomendaciones en CPCP enfermedad limitada, producto de las preguntas de trabajo. Se identificó y evaluó críticamente la evidencia científica que responde a cada una de dichas preguntas clínicas, antes de incorporarla a la guía. Conclusión: Esta guía proporciona recomendaciones clínicas para el manejo de la enfermedad limitada del CPCP y durante el proceso de toma de decisiones de los clínicos involucrados con su manejo en nuestro país para mejorar la calidad de la atención clínica en estos pacientes.

Abstract Background: Small cell lung cancer (SCLC) represents 13-15% of all primary lung neoplasms and is characterized by rapid growth rate and development of distant metastases. Objectives: To guide and standardize the treatment of limited disease small cell lung cancer in Mexico based on national and international clinical evidence. Material and methods: This document was developed as a collaboration between the National Cancer Institute and the Mexican Society of Oncology in compliance with international standards. An interdisciplinary group was formed, including medical oncologists, oncological surgeons, thoracic surgeons, radiation oncologists, and methodologists with experience in systematic reviews of the literature and clinical practice guidelines. Results: Consensus recommendations were reached, both by the Delphi method and in remote meetings, for limited SCLC disease resulting from the same number of work questions. The scientific evidence that answers each of these clinical questions was identified and critically evaluated, before being incorporated into the body of evidence of the guide. Conclusion: This guide provides clinical recommendations for the management of limited disease SCLC to contribute to the decision-making process of the clinicians involved with its management in our country, hoping that this will contribute to improving the quality of clinical care in these patients.

https://doi.org/10.24875/j.gamo.22000121

11.

The evolution research on Silver Economy: Current researches, trends, and implications for future directions Economy researches trends
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Álvarez-Diez, Rubén Carlos

; Vega-Esparza, Reina Margarita

; Bañuelos-García, Víctor Hugo

; López-Robles, José Ricardo

Transinformação

Journal Metrics
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2023, Volume 35 elocation e237325

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A sociedade está passando por transformações sem precedentes causadas por grandes mudanças econômicas, políticas, tecnológicas, sociais e principalmente demográficas. Nesta linha, o papel e o peso dos adultos mais velhos torna-se mais importante devido às modificações que tal transformação trará em suas características, necessidades, expectativas e objetivos no que diz respeito a seus aspectos pessoais, econômicos, políticos, tecnológicos e sociais. Esta situação deu origem ao conceito de Economia da Prata, que representa, de modo geral, a parte da economia relacionada à mudança demográfica causada pelo envelhecimento da população, incluindo todas aquelas atividades econômicas, produtos e serviços destinados a atender as necessidades de adultos idosos. Por ser um campo de conhecimento crescente, torna-se complexo identificar as forças motrizes e agentes que impulsionam seu desenvolvimento e, portanto, promover e consolidar este novo conceito. De acordo com esta oportunidade, este trabalho de pesquisa mapeia os principais temas de pesquisa disponíveis na literatura, fazendo uso de ferramentas e técnicas bibliométricas inteligentes baseadas no SciMAT. Esta pesquisa permite também, identificar os principais temas, quem são os agentes relevantes, os países pioneiros neste campo, assim como as organizações e fontes mais produtivas. Para isso, utilizamos o banco de dados Scopus que concentra 281 publicações de 1979 a 2022 relacionadas aos adultos mais velhos e seu papel no desenvolvimento econômico, político, tecnológico e social, o que resultou em um quadro detalhado de referência sobre a Economia da Prata. econômicas políticas tecnológicas demográficas linha tornase torna se características pessoais econômicos políticos Prata representa geral população idosos crescente portanto oportunidade literatura SciMAT também relevantes produtivas isso 28 197 202 econômico político social 2 19 20 1

Abstract Society is undergoing unprecedented transformations caused by big economic, political, technological, social and mostly demographic changes. In this line, the role and weight of older adults turns more important due to the modifications such transformation will bring about in their characteristics, needs, expectations and goals as regards their personal, economic, political, technological and social aspects. This situation has given rise to the concept of Silver Economy, which broadly speaking represents that part of the economy related to the demographic change caused by aging population, including all those economic activities, products and services intended to meet the needs of older adults. Its being a growing field of knowledge makes it complex to identify the driving forces and agents that boost its development and therefore to promote and consolidate this new concept. In accordance with this opportunity, this piece of research maps the main research themes available in literature, making use of SciMAT-based smart bibliometric tools and techniques. In addition to other actions, this research makes it possible to identify the main themes, who the relevant agents are, the pioneering countries in this field, and the more productive organizations and sources. To this end, the Scopus database has been used as main source, bearing in mind that it concentrates 281 publications from 1979 to 2022 related to older adults and their role in economic, political, technological and social development, which has resulted a detailed frame of reference on Silver Economy. political changes line characteristics personal aspects Economy population activities opportunity literature SciMATbased SciMAT based techniques actions are sources end source 28 197 202 2 19 20 1

https://doi.org/10.1590/2318-0889202335e237325

12.

Riesgo cardiovascular en pacientes ingresados en un Centro de Atención al diabético
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Valle-Pimienta, Tomás

; Gato-Armas, Carlos Alberto

; Rodríguez-López, Medardo

; Hernández-Gómez, José Rafael

; Rosales-Álvarez, Giselys

; Lago-Díaz, Yosdania

Revista Archivo Médico de Camagüey

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2023, Volume 27 elocation e9479

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: Diabetes mellitus is a major health problem worldwide. The cardiovascular risk in diabetic patients is similar to that observed in non-diabetics who have suffered myocardial infarction. Objective: To evaluate the cardiovascular risk in patients admitted to the Diabetic Care Center of Pinar del Río. Methods: A cross-sectional descriptive observational study was carried out in patients admitted to the Diabetic Care Center belonging to the Abel Santamaría Cuadrado General Teaching Hospital in Pinar del Río province, in the period from January 1st, 2019 to December 31st, 2020. The universe of study was made up of 689 patients diagnosed with diabetes mellitus and the sample was 527, selected through simple random probabilistic sampling, with an expected frequency of 50 %, confidence limit 5 % and confidence level 95 %. For the analysis of the information, the statistical system, Statistical Package for Social Sciences, was applied, univariate analysis of a descriptive nature was applied, and descriptive statistics were used, such as the distribution of absolute and relative frequencies. The non-parametric Chi square test was used for qualitative data with a significance level of 95 % (p<0.05). Results : The female sex (53.89 %), age group 60 to 69 years of age (31.31 %) and white-skinned patients (75.9 %) predominated in the series. There was a preponderance of overweight/obesity (74.75 %), followed by arterial hypertension (73.62 %). Low cardiovascular risk prevailed (44.97 %). Conclusions: Diabetes Mellitus is a chronic disease associated with cardiovascular complications that causes increased cardiovascular risk and impaired quality of life. It is essential to establish primary prevention strategies to detect risks early.

RESUMEN Introducción: La diabetes mellitus constituye un importante problema de salud a nivel mundial. El riesgo cardiovascular en pacientes diabéticos es similar al que se observa en no diabéticos que han sufrido infarto del miocardio. Objetivo: Evaluar el riesgo cardiovascular en pacientes ingresados en el Centro de Atención al Diabético de Pinar del Río. Métodos: Se realizó un estudio observacional descriptivo de corte transversal en pacientes ingresados en el Centro de Atención al Diabético perteneciente al Hospital General Docente Abel Santamaría Cuadrado de la provincia Pinar del Río, en el período comprendido desde el 1ro enero de 2019 hasta el 31 diciembre de 2020. El universo de estudio quedó constituido por 689 pacientes con diagnóstico de diabetes mellitus y la muestra por 527, seleccionados a través de un muestreo probabilístico aleatorio simple, con una frecuencia esperada del 50 %, límite de confianza 5 % y nivel de confianza 95 %. Para el análisis de la información se utilizó el sistema estadístico, Statistical Package for Social Sciences, se aplicó análisis univariado de carácter descriptivo, se utilizaron estadígrafos descriptivos como la distribución de frecuencias absoluta y relativa. Se utilizó la prueba no paramétrica Chi cuadrado para datos cualitativos con un nivel de significación del 95 % (p<0,05). Resultados: En la serie predominó el sexo femenino (53,89 %), grupo etario de 60 a 69 años de edad (31,31 %) y afectados de piel blanca (75,9 %). Se observó preponderancia del sobrepeso/obesidad (74,75 %), seguido de la hipertensión arterial (73,62 %). Prevaleció el riesgo cardiovascular bajo (44,97 %). Conclusiones: La diabetes mellitus es una enfermedad crónica asociada a complicaciones cardiovasculares que produce aumento de riesgo cardiovascular y deterioro de la calidad de vida. Resulta fundamental instaurar estrategias de prevención primaria para detectar riesgos en forma temprana.

13.

La certificación de especialistas en medicina familiar en México: 35 años de evolución
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Fernández-Ortega, Miguel A.

; Mazón-Ramírez, Juan J.

; Rivero-López, Carlos A.

; Pons-Álvarez, Octavio Noel

; Portillo-García, Zitlalli

; Hernández-Martínez, Minerva P.

; López-Lozano, Miguel

; Ovando-Diego, Liliana

; Domínguez-del-Olmo, Javier A.

; Palacios-Hernández, Alejandra

; Román-Arrioja, Verónica

; Bailón Ramos, Marco A.

; Tecuanhuey-Tlahuel, Héctor

; Figueroa-Chavira, Ana R.

; López-Salas, Sara de J.

; Huerta-González, José L.

; Avilés-Sánchez, María Emilia

Revista mexicana de medicina familiar

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dec 2022, Volume 9 N. 4 Pages 126 - 132

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN Se presenta la evolución histórica de la certificación de especialistas en medicina familiar en México, a 35 años de su fundación. Asimismo, se abordan brevemente los procesos de evaluación de los sustentantes y la importancia de mantener la «vigencia de la certificación». Se realiza el benchmarking de la certificación en otros países con procesos de certificación bien definidos y consolidados. Al final, se presentan los retos más inmediatos de la certificación en México para esta especialidad.

ABSTRACT: The historical evolution of the Certification of Specialists in Family Medicine in Mexico is presented, 35 years after its foundation. Likewise, the evaluation processes of the applicants and the importance of maintaining the “Certification Validity” are briefly addressed. Certification benchmarking is carried out in other countries with well-defined and consolidated certification processes. At the end, the most immediate challenges of the Certification in Mexico for this specialty are presented.

https://doi.org/10.24875/rmf.22000077

14.

Factors associated with the stigma-discrimination complex towards healthcare workers among university students during the coronavirus pandemic in Mexico
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Cassiani-Miranda, Carlos

; Arismendy-López, Yinneth

; Álvarez-Solorza, Isabel

; Toxqui-Tlachino, María

; Campo-Arias, Adalberto

; Tirado-Otálvaro, Andrés

; Bustamante-Montes, Lilia Patricia

Universidad y Salud

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dec 2022, Volume 24 Suppl. 1 Pages 294 - 300

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Introducción: El estigma relacionado con la COVID-19 hacia los profesionales de la salud influye negativamente en su desempeño laboral y bienestar, sin embargo, este tema no ha sido suficientemente investigado. Objetivo: Determinar la frecuencia y las variables asociadas al estigma relacionado con el COVID-19 hacia los trabajadores de la salud en una población universitaria de México. Materiales y métodos: Estudio transversal. Se envió un cuestionario en línea a 1.054 estudiantes de entre 18 y 29 años. Se analizaron variables demográficas, religión, miedo al COVID-19 y su asociación con el estigma-discriminación hacia el personal de salud relacionado con la COVID-19 (variable dependiente). Se realizó un análisis bivariado y un modelo lineal generalizado para calcular las razones de prevalencia ajustadas. Resultados: La proporción de estigma-discriminación alto fue de 12,4% y se asoció con miedo alto a la COVID-19 RPa=1,51 (IC=95% 1,06-2,23). Conclusión: Los hallazgos destacan la importancia de establecer programas para reducir la estigmatización relacionada con COVID-19 hacia los profesionales de la salud.

Abstract Introduction: COVID-19-related stigma towards healthcare professionals negatively influences their job performance and well-being, however, this issue has not been sufficiently investigated. Objective: To determine the frequency and variables associated with COVID-19-related stigma toward health care workers in a university population in Mexico. Materials and methods: Cross-sectional study. An online questionnaire was sent to 1,054 students between 18 and 29 years of age. Demographic variables, religiosity, fear of COVID-19 and its association with COVID-19-related stigma-discrimination towards health workers (dependent variable) were analyzed. Bivariate analysis and a generalized linear model were performed to calculate adjusted prevalence ratios. Results: The proportion of high stigma-discrimination was 12.4% and was associated with high fear of COVID-19 RPa= 1.51 (95% CI 1.06 - 2.23). Conclusion: The findings highlight the importance of establishing programs to reduce COVID-19-related stigmatization towards healthcare professionals.

https://doi.org/10.22267/rus.222403.285

15.

Code infarction initiative of Bajio region, during the pandemic by COVID-19 in a reconversion hospital
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Villar-Valencia, Cristian Adrián

; Hernández-González, Martha Alicia

; Borrayo-Sánchez, Gabriela

; Celis-Quintal, Juan German

; Solorio-Meza, Sergio Eduardo

; Medina-Torres, Oscar Samuel

; Gutiérrez-Galván, Maraí Xochitl

; Rodríguez-Martínez, Braulio

; Prado-Rodríguez, Luis Humberto

; Vázquez-Morones, Ana Laura

; Alatoma-Medina, Juan Pablo

; Hernández-Estala, Jorge

; Patiño-Amaya, Aristóteles

; Magdaleno-Serrano, Hugo Ivan

; Rodríguez-Déniz, Carmen

; Arellano-Sotelo, Hugo

; Nava-Hernández, Guillermo

; Ramírez-Vázquez, Ricardo

; Chimal-Flores, Marco Antonio

; Alegría-Peredia, Emiliano

; Ramos-González, Gerardo Rubén

; Pérez-Benítez, Rigoberto

; Bermúdez-Acévez, Erik

; Valencia-Martínez, Hypatia

; Segovia-Solís, Hugo

; López-Varela, Manuel

; Monroy-Córdoba, Doryan

; Marmolejo-López, Adriana

; Báez-Montes, Alfredo

; Hernández-Cerqueda, Fabián

; Nolasco-Muñoz, Luis Ricardo

; Vargas-Ramírez, Luis Manuel

; Celis-Quintal, Juan German

; Bernal-Ruíz, Enrique Alfredo

; Delgado-Sánchez, Anabella

; Sánchez-López, José Manuel

; Bautista-López, Germán Ramón

; Acevedo-Gómez, Pablo Francisco

; Acuña-Valerio, Jorge Francisco

; González-Ortíz, Oracio

; Hernández-Padilla, Adolfo Asahel

; Solórzano-Vázquez, Marco Alejandro

; Franco-Herrera, Noel

; González, Luis Jonathan

; Reyes-Álvarez, José Miguel

; Salinas-Cavazos, Iván Rosendo

; Tiscareño-Villanueva, Ashby Daniel

; Vidrio-Villaseñor, Ramiro

; Fernández-Yáñez, Gabriel

; Meza, Ma. Guadalupe

; Nucamendi-Solórzano, Freeman Issac

; Sandoval-Uribe, José de Jesús

; Sotelo-García, Luis David

; Zamoaya-Paz, Luis Carlos

; Espriu, Donovan Fernando

; García-Rodríguez, Román

; López-Ibarra, Daniel Eugenio

; López-Valencia, Andrea Janeth

; Villar-Valencia, Cristian Adrián

; Navarro-Pérez-Macedo, Javier

Cardiovascular and metabolic science

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sep 2022, Volume 33 N. 3 Pages 97 - 105

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract: Introduction: Acute myocardial infarction has a high prevalence and possibility of death if timely care is not given. It is possible that treatment could be delayed during a health crisis such as the COVID-19 pandemic. Objective: The objective of this study was to evaluate the impact of the COVID-19 pandemic on the function of the infarction code in the High Specialty Medical Unit of our institution. The medical indicators of acute coronary ischemic syndrome with ST-segment elevation were compared at two times: before the COVID-19 pandemic and during it. Material and methods: An ambispective, analytical, comparative cohort study was conducted, comparing the periods of February-September 2019 and February-September 2020, in the High Specialty Medical Unit, Centro Médico del Bajío number 1, Instituto Mexicano del Seguro Social, Leon, Guanajuato, Mexico. All patients older than 18 years with clinical, electrocardiographic, and enzymatic data of acute coronary ischemic syndrome, accepted in the medical network as infarction code registered in the National Registry of Acute Coronary Ischemic Syndromes (RENASCA) electronic case report form were included in the study. Results: The independent samples t-test was used to determine the impact of the infarction code initiative based on the reperfusion therapies performed, the door-to-needle, the door-to-balloon time, and the ischemia time. There was a significant difference in the reperfusion strategy, with greater thrombolysis during the COVID-19 pandemic (57.4% versus 72.6%, odds ratio [OR] 1.97, 95% confidence interval [CI] 0.49-0.82, p < 0.001), as well as reperfusion criteria (21.03% versus 35.37%, OR 2.05, 95% CI 0.53-0.80, p < 0.0001). Mortality was not different between the time periods. Conclusions: The COVID-19 pandemic has not impacted operation of the infarction code in the High Specialty Medical Unit Centro Médico del Bajío number 1 because the medical indicators of acute coronary ischemic syndrome with ST-segment elevation did not change.

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https://doi.org/10.35366/107622

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