Chronic mucocutaneous candidiasis is a rare disorder characterized by persistent and recurrent infections by Candida due to changes in cellular immunity and may be associated with autoimmune endocrine disorders. It is refractory to the usual antifungal treatments, which merely control it with imidazole derivatives. This reports the case of a 50-year-old female patient who referred vaginal discharge associated with vulvar ulcerated lesions and whitish plaques on oral and genital mucous membranes of onset in adolescence besides cutaneous horns in nipples. The clinical picture, family history, culture and anatomopathological studies were consistent with chronic infection by candida. Treatment with systemic antifungals obtained partial response of lesions characterizing a clinical picture of Chronic Mucocutaneous Candidiasis.

O carcinoma basocelular é a neoplasia maligna cutânea mais comum em humanos, localizando-se, frequentemente, em áreas expostas e em indivíduos de pele clara. Relata-se o caso de uma paciente de 62 anos, faiodérmica, com múltiplas lesões de bordas discretamente elevadas, eritemato-acastanhadas na região pubiana, cujo diagnóstico clínico foi carcinoma basocelular pigmentado, confirmado através do estudo histopatológico. A imunoistoquímica das lesões foi negativa para a pesquisa de papiloma vírus

Basal cell carcinoma is the most common type of malignant cutaneous neoplasm in humans, being more frequently located in exposed areas and in fair-skinned individuals. It is reported the case of a 62-yearold female patient, brown-skinned ,with multiple lesions with edges slightly raised, reddish-brown in the pubic region, whose clinical diagnosis was pigmented basal cell carcinoma, confirmed by histopathology. Immunohistochemistry of the lesions was negative for the detection of papilloma virus

Paciente de 29 anos, do sexo feminino, com aparecimento há quatro anos de pápulas assintomáticas, eritêmato-acastanhadas, no antebraço direito. Duas das lesões foram biopsiadas para exames histopatológico e imuno-histoquímico. A paciente foi inicialmente tratada com corticoterapia intralesional, sem melhora. Procedeu-se, então, à exérese das lesões com resolução completa do quadro.

A 29-year-old female patient with asymptomatic red-brown papules that had arisen four years before in her right forearm. Two lesions were removed for histopathological and immunohistochemical exams. Intralesional corticosteroid injection resulted in no improvement and the lesions were subsequently surgically excised with complete resolution of the condition.

Descreve-se caso clínico de paciente tratado de hanseníase dimorfa, que utilizou automedicação, com doses variadas de corticosteróide oral, por longo período, devido à neuropatia hansênica. Desenvolveu lesão nódulo-cística, amarelada, com algumas crostas, envolta por halo eritêmato-acastanhado, na face interna da perna esquerda. O exame micológico direto confirmou a hipótese diagnóstica de feo-hifomicose.

We report a patient suffering from dimorphic Hansen's disease who has self medicated his neuropathy with oral corticosteroid for a long time. A yellowish, nodular-cystic lesion partially topped with crusting, surrounded by a brownish red halo, was noted on the inner aspect of his left leg. Direct mycological examination confirmed the hypothesis of pheohyphomycosis.

As epidermólises bolhosas são dermatoses bolhosas congênitas que levam à formação de bolhas espontaneamente ou após trauma. São reconhecidos três grupos de da doença, de acordo com o segundo consenso internacional: simples, juncional e distrófica. Nas formas distróficas, o defeito genético deve-se à mutação no gene COL7A1, responsável pela codificação do colágeno VII, principal constituinte das fibrilas de ancoragem, que participam na aderência da lâmina densa à derme. Os autores relatam o caso de paciente do sexo feminino, de 15 anos, apresentando ulcerações nas pernas, bolhas serosas e lesões atrófico-acastanhadas nos braços e tronco. Foram observadas distrofias ungueais e alterações dentárias, iniciadas a partir do nascimento. O exame histopatológico da bolha revelou quadro compatével com epidermólise bolhosa, que, associado aos dados clínicos, permitiram a classificação do caso na forma distrófica recessiva mitis.

Epidermolysis bullosa are congenital bullous dermatoses that lead to spontaneous or post-traumatic formation of blisters. There are three recognized disease groups, according to the second international consensus: simplex, junctional and dystrophic. The genetic defect of the dystrophic forms is due to a mutation in the COL7A1 gene, which is responsible for codifying collagen VII, the main representative of anchoring fibrils, which participate in the adherence of the "lamina densa" to the dermis. The authors describe a case of a 15 year-old female patient who presented ulcers on her legs, serous blisters and atrophic scars on her arms and body. Dystrophic ungual and dental abnormalities had also been observed since her birth. Blister histopathological examination was compatible with epidermolysis bullosa, which, in association with clinical data, allowed the classification of recessive distrophic epidermolysis bullosa.

A piedra branca é infecção fúngica do pêlo, rara, causada pelo Trichosporon beigelii, caracterizada por nódulos amarelados nos pêlos genitais, bigode, barba, axilas e raramente, no couro cabeludo. O estudo registra 15 casos, diagnosticados em serviço de dermatologia de Vitória, durante cinco anos, todos de pacientes do sexo feminino, com nódulos nos pêlos do couro cabeludo. Os autores supõem que o clima quente e úmido da região e o hábito de as pacientes utilizarem cremes recondicionadores nos fios dos cabelos tenham favorecido a infecção. O umedecimento dos fios com água facilita a visualização dos nódulos.

White Piedra is a rare fungal infection of the hair shaft, caused by a yeast-like fungus (Trichosporon beigelii), characterized by yellow nodules on the pubic hair, moustache, beard and hair on the axillae and scalp. The objective was to register the presence of 15 cases of White Piedra in Espírito Santo diagnosed at the Dermatology Service in Vitória, over five years. All patients were female with nodules in the scalp hair, 13 were of mixed race and ten were between two and six years old. The hot and humid climate of the region together with the patients' habits regarding use of conditioning creams favored the infection. Moistening the hair with water can facilitate visualization of the nodules.