ABSTRACT The objective of the present study was to evaluate the early regeneration stage in previously deforested and cattle-occupied areas of high montane mixed forest in São Joaquim National Park, in the "Planalto Sul Catarinense" region. The study was conducted in two areas in the early successional stage, which had already been inventoried in 2014 and 2018. In each area, 20 plots of 10 x 10 m were established in transects of 20 x 100 m. In 2022, the sites were inventoried again, with all living (? 1 m in height and < 5 cm DBH - diameter at breast height), recruited (? 1 m in height), dead, and outgrowth (? 5 cm DBH) individuals recorded and identified (recruited). The effective richness (Number of Hill) and dynamic rates were determined for the inventory periods (2014-2018-2022). The results show that succession occurs in the areas as species richness increases and dynamic turnover decreases. We conclude that succession occurs with great spatial and temporal heterogeneity. Populations can be grouped according to their dynamic patterns (fast-slow) and ability to become established in the areas (winners-losers). cattleoccupied cattle occupied Park Planalto Catarinense region 201 2018 area 2 2022 again ( height, , height) dead recruited. . (recruited) Number Hill 201420182022. 201420182022 (2014-2018-2022) decreases heterogeneity fastslow fast slow (fast-slow winnerslosers. winnerslosers winners losers (winners-losers) 202 (recruited 20142018202 (2014-2018-2022 (winners-losers 2014201820 (2014-2018-202 201420182 (2014-2018-20 20142018 (2014-2018-2 2014201 (2014-2018- 201420 (2014-2018 20142 (2014-201 (2014-20 (2014-2 (2014- (2014 (201 (20 (2

RESUMO O presente estudo teve como objetivo avaliar o estágio inicial de regeneração em áreas anteriormente desmatadas e ocupadas por gado, na Floresta Ombrófila Mista Alto-Montana, no Parque Nacional de São Joaquim, Planalto Catarinense. Realizou-se o estudo em duas áreas em estágio sucessional inicial, que foram previamente inventariadas nos anos de 2014 e 2018. A amostragem em cada área foi por meio de 20 parcelas por área, de 10 x 10 m, distribuídas em transecções de 20 x 100 m. Em 2022, as áreas foram novamente inventariadas, sendo todos os indivíduos com altura ? 1 m e DAP < 5 cm medidos (altura) e, no caso de recrutas, identificados, quantificando-se, também, indivíduos mortos e que se tornaram adultos (? 5 cm). Foram obtidas a riqueza efetiva (Número de Hill) e taxas de dinâmica para os períodos de inventário (2014-2018-2022). Os resultados evidenciaram o avanço da sucessão nas áreas, em virtude do aumento da diversidade de espécies, assim como a redução da rotatividade da dinâmica. Conclui-se que o avanço da trajetória sucessional ocorre de forma a apresentar elevada heterogeneidade espaço-temporal. Quanto às populações existentes, puderam ser agrupadas em função de seus padrões de dinâmica (rápida-lenta) e capacidade de estabelecimento nas áreas (vencedoras-perdedoras). gado AltoMontana, AltoMontana Alto Montana, Montana Alto-Montana Joaquim Catarinense Realizouse Realizou 201 2018 2 2022 (altura recrutas identificados quantificandose, quantificandose quantificando se, quantificando-se também ( cm. . cm) Número Hill 201420182022. 201420182022 (2014-2018-2022) espécies Concluise Conclui espaçotemporal. espaçotemporal espaço temporal. temporal espaço-temporal existentes rápidalenta rápida lenta (rápida-lenta vencedorasperdedoras. vencedorasperdedoras vencedoras perdedoras (vencedoras-perdedoras) 202 20142018202 (2014-2018-2022 (vencedoras-perdedoras 2014201820 (2014-2018-202 201420182 (2014-2018-20 20142018 (2014-2018-2 2014201 (2014-2018- 201420 (2014-2018 20142 (2014-201 (2014-20 (2014-2 (2014- (2014 (201 (20 (2

Abstract Aging has a direct impact on balance due to changes in sensory and motor response, sarcopenia, reduced muscle strength and range of motion that occur in the elderly. In this context, strength training (ST) programs are seen as a valuable strategy to minimize the deleterious effect of aging on strength production and balance in this population. The purpose of the study was to evaluate the effect of 12 weeks of progressive intensity ST on static balance variables in the elderly. The study included 23 elderly with an average age of 65±8.61 years, of both sexes, who performed a twelve-week strength training program, with a frequency of three times a week and with progressive intensity (60 - 85% of 1-RM). Balance was assessed before and after the intervention period, through stabilometric assessment on a force plate. After the intervention, there was a reduction in the anteroposterior amplitude (p=0.01), in the anteroposterior velocity (p=0.01) and in the total displaced area (p=0.04). It is concluded that the strength training can be used as a key tool to minimize the deleterious effect of aging on the maintenance of static balance. response sarcopenia context (ST population 1 2 65861 65 8 61 65±8.6 years sexes twelveweek twelve program 60 (6 85 1RM. 1RM RM . 1-RM) period plate p=0.01, p001 p p=0.01 , 0 01 (p=0.01 p=0.04. p004 p=0.04 04 (p=0.04) 6586 6 65±8. ( 1-RM p00 p=0.0 (p=0.0 (p=0.04 658 65±8 p0 p=0. (p=0. 65± p=0 (p=0 p= (p= (p

Resumo O envelhecimento tem impacto direto no equilíbrio devido a alterações da resposta sensorial e motora, sarcopenia e redução da força muscular e da amplitude de movimento que ocorre nos idosos. Nesse contexto, programas de treinamento de força (TF) são vistos como valiosa estratégia para minimizar o efeito deletério do envelhecimento na produção de força e no equilíbrio dessa população. O objetivo do estudo foi avaliar o efeito de 12 semanas de TF com intensidade progressiva sobre as variáveis de equilíbrio estático em idosos. Participaram do estudo 23 idosos com idade média de 65±8,61 anos, de ambos os sexos, que realizaram um programa de TF de doze semanas, com frequência de três vezes por semana e com intensidade progressiva (60 - 85% de 1-RM). O equilíbrio foi avaliado antes e após o período de intervenção, por meio de avaliação estabilométrica em plataforma de força. Após a intervenção houve redução na amplitude anteroposterior (p=0,01), na velocidade anteroposterior (p=0,01) e na área total deslocada (p= 0,04). Conclui-se que o treinamento de força pode ser utilizado como ferramenta chave para minimizar o efeito deletério do envelhecimento na manutenção do equilíbrio estático. motora contexto (TF população 1 2 65861 65 8 61 65±8,6 anos sexos 60 (6 85 1RM. 1RM RM . 1-RM) p=0,01, p001 p p=0,01 , 0 01 (p=0,01 p= (p 0,04. 004 0,04 04 0,04) Concluise Conclui se 6586 6 65±8, ( 1-RM p00 p=0,0 (p=0,0 00 0,0 658 65±8 p0 p=0, (p=0, 0, 65± p=0 (p=0

BACKGROUND Leishmania tarentolae is a non-pathogenic species found in lizards representing an important model for Leishmania biology. However, several aspects of this Sauroleishmania remain unknown to explain its low level of virulence. OBJECTIVES We reported several aspects of L. tarentolae biology including glycoconjugates, proteolytic activities and metabolome composition in comparison to pathogenic species (Leishmania amazonensis, Leishmania braziliensis, Leishmania infantum and Leishmania major). METHODS Parasites were cultured for extraction and purification of lipophosphoglycan (LPG), immunofluorescence probing with anti-gp63 and resistance against complement. Parasite extracts were also tested for proteases activity and metabolome composition. FINDINGS Leishmania tarentolae does not express LPG on its surface. It expresses gp63 at lower levels compared to pathogenic species and, is highly sensitive to complement-mediated lysis. This species also lacks intracellular/extracellular activities of proteolytic enzymes. It has metabolic differences with pathogenic species, exhibiting a lower abundance of metabolites including ABC transporters, biosynthesis of unsaturated fatty acids and steroids, TCA cycle, glycine/serine/threonine metabolism, glyoxylate/dicarboxylate metabolism and pentose-phosphate pathways. MAIN CONCLUSIONS The non-pathogenic phenotype of L. tarentolae is associated with alterations in several biochemical and molecular features. This reinforces the need of comparative studies between pathogenic and non-pathogenic species to elucidate the molecular mechanisms of virulence during host-parasite interactions. nonpathogenic non However L glycoconjugates amazonensis braziliensis major. major . major) LPG, , (LPG) antigp63 antigp anti gp anti-gp6 complement surface gp6 complementmediated mediated lysis intracellularextracellular intracellular extracellular enzymes transporters steroids cycle glycineserinethreonine glycine serine threonine glyoxylatedicarboxylate glyoxylate dicarboxylate pentosephosphate pentose phosphate pathways features hostparasite host parasite interactions (LPG antigp6 anti-gp

ABSTRACT Dopamine agonists are the first line of treatment for patients with symptomatic hyperprolactinemia due to prolactinomas and in those with idiopathic hyperprolactinemia. Treatment with these agents is effective in 80%-90% of the cases. Infertility treatment of patients with hyperprolactinemia is also carried out with dopamine agonists, aiming for the normalization of prolactin levels. The risk of symptomatic growth of prolactinomas during pregnancy is dependent on the tumor's size, duration of previous treatments, and prolactin levels. Notably, the corresponding risk is relatively low in cases of microprolactinomas (<5%). Remission of hyperprolactinemia occurs in about 30% of the patients after drug treatment and may also occur after pregnancy and menopause. The use of some drugs, such as antidepressants and antipsychotics, is a frequent cause of hyperprolactinemia, and managing this occurrence involves unique considerations. This position statement by the Brazilian Federation of Gynecology and Obstetrics Associations (Febrasgo) and Brazilian Society of Endocrinology and Metabolism (SBEM) addresses the recommendations for measurement of serum prolactin levels and the investigations of symptomatic and asymptomatic hyperprolactinemia and drug-induced hyperprolactinemia in women. 80%90% 8090 80% 90% 80 90 80%-90 tumors tumor s size treatments Notably <5%. 5 <5% . (<5%) 30 menopause drugs antipsychotics considerations Febrasgo (Febrasgo SBEM (SBEM druginduced induced women 80%90 809 8 9 80%-9 <5 (<5% 3 80%9 80%- < (<5 (< (

ABSTRACT Hyperprolactinemia is a frequent cause of menstrual irregularity, galactorrhea, hypogonadism, and infertility. The most common etiologies of hyperprolactinemia can be classified as physiological, pharmacological, and pathological. Among pathological conditions, it is essential to distinguish prolactinomas from other tumors and pituitary lesions presenting with hyperprolactinemia due to pituitary stalk disconnection. Proper investigation considering clinical data, laboratory tests, and, if necessary, imaging evaluation, is important to identify the correct cause of hyperprolactinemia and manage the patient properly. This position statement by the Brazilian Federation of Gynecology and Obstetrics Associations (Febrasgo) and Brazilian Society of Endocrinology and Metabolism (SBEM) addresses the recommendations for measurement of serum prolactin levels and the investigations of symptomatic and asymptomatic hyperprolactinemia and medication-induced hyperprolactinemia in women. irregularity galactorrhea hypogonadism infertility physiological pharmacological conditions disconnection data tests necessary evaluation properly Febrasgo (Febrasgo SBEM (SBEM medicationinduced medication induced women

Abstract Synthesising knowledge on carbon stocks is an essential tool for understanding the potential of forests to store carbon and its drivers. However, such a synthesis needs to be constructed for the Atlantic Forest due to various methodological approaches and biogeographic heterogeneity. Thus, here we conducted a bibliographic search (2000 to 2021) on carbon stocks in the biomass and necromass of Atlantic Forest ecosystems to understand the variation in stocks and their explanatory variables. Drivers included spatial (altitude, forest size) and climatic (precipitation and temperature) variables, and successional stages. Based on the information in 46 articles, biomass exhibited the highest carbon stock (96%), in Mature Forests (MF), with an average of 125.34±40.3 MgC.ha-1, whereas Secondary Forests (SF) stored 82.7±38.2 MgC.ha-1. The carbon in the necromass varied from 1.63 to 11.47 MgC.ha-1, with SF exhibiting 3.90±2.73 MgC.ha-1 and MF 4.31±2.82 MgC.ha-1. Only average annual precipitation and successional stage positively explained the carbon in Atlantic Forest. This research clarifies the function and potential of Atlantic Forest fragments for storing carbon and reinforces need for conserving mature forest patches throughout the biome since one hectare of mature forest can store almost twice as much carbon as one hectare of secondary young patches. drivers However heterogeneity Thus 2000 (200 2021 variables altitude, altitude (altitude size temperature stages 4 articles 96%, 96 96% , (96%) MF, (MF) 12534403 125 34 40 3 125.34±40. MgC.ha1, MgCha1 MgCha MgC.ha 1, MgC ha 1 (SF 827382 82 7 38 2 82.7±38. MgC.ha1. 1. 163 63 1.6 1147 11 47 11.4 390273 90 73 3.90±2.7 MgC.ha1 MgC.ha- 431282 31 4.31±2.8 200 (20 202 9 (96% (MF 1253440 12 125.34±40 ha1 82738 8 82.7±38 16 6 114 11. 39027 3.90±2. 43128 4.31±2. 20 (2 (96 125344 125.34±4 8273 82.7±3 3902 3.90±2 4312 4.31±2 ( (9 12534 125.34± 827 82.7± 390 3.90± 431 4.31± 1253 125.34 82.7 39 3.90 43 4.31 125.3 82. 3.9 4.3 125. 3. 4.

Abstract Borosilicate glass was developed to enhance the mechanical behavior and smoothness of dental zirconia as an alternative to conventional glaze. This study assessed the mechanical and optical properties of 3 mol% yttria-stabilized tetragonal zirconia polycrystal (3Y-TZP) coated with borosilicate glass or a commercial glaze fired for an extended period of time. Disc-shaped 3Y-TZP zirconia specimens (Zpex, Tosoh) were sintered at 1550°C for 2 hours. The specimens were divided into three groups: as-sintered (control, C); commercial glaze (G); and borosilicate glass (SL). The glaze and borosilicate glass were applied over the zirconia and fired for 20 minutes at 950°C and 1200°C, respectively. Biaxial flexural strength, fractography, X-ray diffraction (XRD), roughness (Ra and Rz), fracture toughness (Vickers indentation method), color difference (∆E00), and translucency (TP00) analyses were conducted. The t-test or the one-way ANOVA and Tukey’s tests were used to analyze the data (α = 0.05). Flexural strength data were subjected to the Weibull analysis. The SL group exhibited the highest flexural strength (1025.8 MPa), whereas the C (859.41 MPa) and G (816.0 MPa) groups exhibited similar values. The SL group also had the highest characteristic strength. The fracture origin in all groups was on the zirconia surface. XRD analysis revealed that the specimens from the SL group contained tetragonal, cubic, and monoclinic phases. The SL group presented the lowest surface roughness. Fracture toughness in the SL group was lower than in the C group, but similar to that observed in the G group. The translucency and color differences observed in the G and SL groups were similar. Borosilicate glass enhanced the flexural strength of 3Y-TZP, promoted the smoothest surface, and exhibited optical properties similar to those of the glaze. mol yttriastabilized yttria stabilized 3YTZP YTZP 3Y TZP Y (3Y-TZP time Discshaped Disc shaped Zpex, Zpex (Zpex Tosoh 1550C 1550 hours assintered control, control (control C) (G) SL. . (SL) 950C 950 1200C 1200 1200°C respectively fractography Xray X ray XRD, , (XRD) Ra Rz, Rz Rz) Vickers method, method method) ∆E00, E00 E ∆E00 (∆E00) TP00 TP (TP00 conducted ttest t test oneway one way Tukeys Tukey s α 0.05. 005 0.05 0 05 0.05) 1025.8 10258 1025 8 (1025. MPa, MPa 859.41 85941 859 41 (859.4 816.0 8160 816 (816. values cubic phases 3YTZP, TZP, 155 (G (SL 95 120 (XRD E0 ∆E0 (∆E00 TP0 (TP0 00 0.0 1025. 102 (1025 859.4 8594 85 4 (859. 816. 81 (816 15 9 12 ∆E (∆E0 (TP 0. 10 (102 859. (859 (81 1 (∆E (10 (85 (8 (1 (

Abstract The study aimed to evaluate relative validity and reproducibility of seven WHO indicators of dietary practices in children aged 6-23.9 months. Data from probabilistic sample of children who used primary healthcare services in Rio de Janeiro, Brazil were collected using a 24h dietary recall (24HR) and a closed questionnaire (Q1) on feeding in the day before the study. The last one was reapplied (Q2) around 16 days later. Validity was assessed by comparing the prevalence rates estimated by 24HR and Q1 and calculating the positive (PPV) and negative (NPV) predictive values, sensitivity (Se), specificity (Sp), and accuracy index (AI) for the resulting indicators. For reproducibility, estimated prevalence rates based on Q1 and Q2 were compared and the kappa index and prevalence-adjusted bias-adjusted kappa were estimated. Of the seven estimated indicators, the prevalence of two was overestimated (Continued breastfeeding: 50.0% vs 40.0%; Sweet beverage consumption: 65.1% vs 52.7%) and the prevalence of one was underestimated (Zero vegetable or fruit consumption: 6.5% vs 18.1%). For most indicators, Se and PPV were higher than Sp and NPV. The prevalence rates determined with Q1 and Q2 were similar for 6 indicators. More than half showed good, very good or excellent agreement. 623.9 6239 23.9 23 9 6-23. months Janeiro h HR (24HR Q (Q1 (Q2 1 later (PPV NPV (NPV values Se, , (Se) Sp, (Sp) AI (AI prevalenceadjusted adjusted biasadjusted bias Continued breastfeeding 500 50 0 50.0 40.0% 400 40 consumption 651 65 65.1 52.7% 527 52 7 Zero 5 6.5 18.1%. 181 18.1% . 18 18.1%) agreement 623 623. 239 23. 2 6-23 (Q (Se (Sp 50. 40.0 4 65. 52.7 6. 18.1 62 6-2 40. 52. 18. 6-

Resumo O estudo avaliou a validade relativa e a reprodutibilidade de sete indicadores da OMS sobre alimentação de crianças de 6-23,9 meses. Dados de amostra probabilística de usuários de serviços básicos de saúde na cidade do Rio de Janeiro, Brasil, foram coletados por meio de recordatório alimentar de 24 horas (R24h) e questionário fechado (Q1) sobre alimentação no dia anterior ao estudo. Este último foi reaplicado (Q2) em torno de 16 dias depois. A validade foi avaliada comparando-se as prevalências estimadas pelo R24h e Q1 e calculando-se os valores preditivos positivo (VPP) e negativo (VPN), sensibilidade (Se), especificidade (Esp) e índice de acurácia (IA) dos indicadores resultantes. Para reprodutibilidade, as prevalências estimadas com base em Q1 e Q2 foram comparadas e estimados o índice kappa e o kappa ajustado pela prevalência. Dos sete indicadores estimados, houve superestimação da prevalência de dois (aleitamento continuado: 50,0% versus 40,0%; consumo de bebidas adoçadas: 65,1% vs. 52,7%) e subestimação da prevalência de um (não consumo de frutas e hortaliças: 6,5% vs. 18,1%). Para a maioria deles, Se e VPP foram maiores do que Esp e VPN. As prevalências determinadas com Q1 e Q2 foram semelhantes para seis indicadores. Mais da metade dos indicadores apresentaram concordância boa, muito boa ou excelente. 623,9 6239 6 23,9 23 9 6-23, meses Janeiro Brasil 2 Rh R h (R24h Q (Q1 (Q2 1 depois comparandose comparando se calculandose calculando (VPP VPN, VPN , (VPN) Se, (Se) (Esp IA (IA resultantes aleitamento continuado 500 50 0 50,0 40,0% 400 40 adoçadas 651 65 65,1 vs 52,7% 527 52 7 não hortaliças 5 6,5 18,1%. 181 18,1% . 18 18,1%) deles excelente 623 623, 239 23, 6-23 (Q (VPN (Se 50, 40,0 4 65, 52,7 6, 18,1 62 6-2 40, 52, 18, 6-

Abstract The present study evaluated the promotion of natural/minimally processed foods (N/MPF) subgroups advertised in supermarket circulars by considering supermarket features and circular typology. We analyzed circulars published by five supermarket chains in the metropolitan region of Rio de Janeiro (June/2019-May/2020) and present data on the socioeconomic coverage and profile of the supermarkets and the types of circulars. Of the 68,110 types of foods, 30.6% were N/MPF. Meat/eggs were the most promoted ones (42.3%), followed by fruits/vegetables (20.2%), which were more often advertised by produce shop circulars. Dairy products, cereals/flours/pasta and beverages/infusions made up around 10.0% of the ads. Legumes (3.8%), spices and mushrooms (0.2%) and oilseeds (0.1%) were rarely promoted. Statistically significant differences were found in the promotion of subgroups according to supermarket coverage and their socioeconomic profiles. Fruits/vegetables were more often advertised by national chains and aimed at a high-income public than by local companies and aimed at a low/middle-income public. Promotion of N/MPF subgroups was disproportional due to differences among chains and types of circulars. As a result, a discussion on the regulation of food promotion in food retail is required. naturalminimally natural minimally NMPF N MPF (N/MPF typology June/2019May/2020 June2019May2020 JuneMay June/2019 May/2020 June 2019 May 2020 (June/2019-May/2020 68110 68 110 68,11 306 30 6 30.6 Meateggs Meat eggs 42.3%, 423 42.3% , 42 3 (42.3%) fruitsvegetables fruits vegetables 20.2%, 202 20.2% 20 2 (20.2%) products cerealsflourspasta cereals flours pasta beveragesinfusions beverages infusions 100 10 0 10.0 ads 3.8%, 38 3.8% 8 (3.8%) 0.2% 02 (0.2% 0.1% 01 1 (0.1% profiles Fruitsvegetables Fruits highincome high income low/middleincome lowmiddleincome low/middle low middle result required 2019May June/2019May/202 June2019May202 June2019 June/201 May2020 May/202 201 (June/2019-May/202 6811 11 68,1 30. 42.3 4 (42.3% 20.2 (20.2% 10. 3.8 (3.8% 0.2 (0.2 0.1 (0.1 middleincome lowmiddle June/2019May/20 June2019May20 June201 June/20 May202 May/20 (June/2019-May/20 681 68, 42. (42.3 20. (20.2 3. (3.8 0. (0. June/2019May/2 June2019May2 June20 June/2 May20 May/2 (June/2019-May/2 (42. (20. (3. (0 June/2019May/ June2019May June2 June/ May2 May/ (June/2019-May/ (42 (20 (3 ( June/2019May (June/2019-May (4 (2

Resumo O estudo visa avaliar a promoção dos subgrupos de AIN/MP anunciados em encartes de supermercados, considerando as características das redes e a tipologia dos encartes. Foram analisados encartes de cinco redes de supermercados da região metropolitana do Rio de Janeiro (junho/2019-maio/2020). Foram apresentados dados de abrangência e perfil socioeconômico das redes e tipo de encarte. Dos 68.110 alimentos, 30,6% são AIN/MP. Carnes/ovos foram mais promovidos (42,3%), seguido de frutas/hortaliças (20,2%) anunciados mais em encartes de hortifruti. Laticínios; cereais/farinhas/massas e bebidas/infusões representaram cerca de 10,0% dos anúncios. Leguminosas (3,8%), especiarias e cogumelos (0,2%) e oleaginosas (0,1%) foram pouco promovidos. Foram encontradas diferenças estatisticamente significativas na promoção de subgrupos segundo abrangência e perfil socioeconômico das redes. Frutas/hortaliças foram mais anunciadas em redes nacionais e voltadas para o público de alta renda em comparação às locais e voltadas para um público de média/baixa renda. Constatou-se desequilíbrio na promoção dos subgrupos de AIN/MP, com diferenças entre as redes e os tipos de encartes. Diante disto, deve-se dar luz à discussão sobre a regulação da promoção de alimentos no varejo alimentar. AINMP AIN MP junho/2019maio/2020. junho2019maio2020 junhomaio junho/2019 maio/2020 . junho 2019 maio 2020 (junho/2019-maio/2020) encarte 68110 68 110 68.11 306 30 6 30,6 Carnesovos Carnes ovos 42,3%, 423 42,3% , 42 3 (42,3%) frutashortaliças frutas hortaliças 20,2% 202 20 2 (20,2% hortifruti Laticínios cereaisfarinhasmassas cereais farinhas massas bebidasinfusões bebidas infusões 100 10 0 10,0 anúncios 3,8%, 38 3,8% 8 (3,8%) 0,2% 02 (0,2% 0,1% 01 1 (0,1% Frutashortaliças Frutas médiabaixa média baixa Constatouse Constatou se disto devese deve alimentar 2019maio junho/2019maio/2020 junho2019maio202 junho2019 junho/201 maio2020 maio/202 201 (junho/2019-maio/2020 6811 11 68.1 30, 42,3 4 (42,3% 20,2 (20,2 10, 3,8 (3,8% 0,2 (0,2 0,1 (0,1 junho/2019maio/202 junho2019maio20 junho201 junho/20 maio202 maio/20 (junho/2019-maio/202 681 68. 42, (42,3 20, (20, 3, (3,8 0, (0, junho/2019maio/20 junho2019maio2 junho20 junho/2 maio20 maio/2 (junho/2019-maio/20 (42, (20 (3, (0 junho/2019maio/2 junho2019maio junho2 junho/ maio2 maio/ (junho/2019-maio/2 (42 (2 (3 ( junho/2019maio/ (junho/2019-maio/ (4 junho/2019maio (junho/2019-maio

ABSTRACT Climate change represents one of the greatest threats to global biodiversity. We investigate how climate change will affect the future potential distribution of tree species in subtropical high montane habitats in the Atlantic Forest and identify potential climate refuges for these species. The most frequent and exclusive species in this ecosystem were selected and geographic coordinates were compiled. The maximum entropy algorithm was used for climatic niche modeling. Two scenarios for 2061-2080 were considered for future predictions, one low impact (RCP 4.5) and one high impact (RCP 8.5). Isothermality, mean temperature in the driest quarter, mean temperature in the hottest quarter, rainfall in the driest month, and rainfall in the hottest quarter were the variables that best explained the climatic niche of the majority of species. The areas of potential species occurrence were reduced by 48.37 % (± 13.63 %) (RCP 4.5) and 62.49 % (± 21.87 %) (RCP 8.5) on average. The potential area of Crinodendron brasilense Reitz & L.B.Sm. decreased the most, by 82.11 % (RCP 4.5) and 90.06 % (RCP 8.5), respectively. High elevation areas in the south of Brazil were identified as priorities for conservation to ensure that climate refuges for high montane forest species are maintained in the future. Climate change events may significantly affect the species evaluated in this study. biodiversity compiled modeling 20612080 2061 2080 2061-208 predictions RCP 4.5 45 4 5 8.5. 85 8.5 . 8 Isothermality month 4837 48 37 48.3 ± ( 1363 13 63 13.6 6249 62 49 62.4 2187 21 87 21.8 average LBSm L B Sm L.B.Sm 8211 82 11 82.1 9006 90 06 90.0 8.5, , respectively study 2061208 206 208 2061-20 4. 8. 483 3 48. 136 1 6 13. 624 62. 218 2 21. 821 82. 900 9 0 90. 206120 20 2061-2 20612 2061-

Numerical simulation was used to predict the thermal behavior and the resulting microstructure at the heat-affected zone (HAZ) of a 170 mm diameter and 3.5 mm thickness super duplex stainless steel (SDSS) UNS S32750 tube. In order to evaluate the thermal response from the model, a usual welding situation involving interpass temperature (IT) and its influence on the HAZ microstructure was exploited. Thus, two superimposed autogenous welding passes were simulated, the first clockwise with the tube in the room temperature and the second, counterclockwise, with the tube at the temperature of 250oC. Even subjected to successive thermal cycles and high interpass temperature, the proportion and morphology of the phases at the HAZ and Fusion Zone (FZ) did not present significant differences when comparing the two welding passes. Meanwhile, nitrogen losses should be avoided during welding in order to obtain a balanced microstructure in DSS welds, contributing to guarantee satisfactory toughness in addition to resistance to pitting corrosion. The predictions from the simulation were validated by using experimental results obtained from the autogenous TIG (Tungsten Inert Gas) process. heataffected heat affected (HAZ 17 35 3 5 3. SDSS (SDSS S S3275 model IT (IT exploited Thus simulated second counterclockwise 250oC oC FZ (FZ Meanwhile welds corrosion Tungsten Gas process 1 S327 S32 S3

Resumen Considerando que experiencia una disfunción sexual afecta profundamente la autopercepción y la calidad de vida, este trabajo tiene como objetivo comprender la experiencia de vivir con vaginismo. Se trata de una investigación empírica, cualitativa, exploratoria, en la que participaron nueve mujeres diagnosticadas de vaginismo en algún momento de su vida. Los datos fueron recolectados a través de entrevistas individuales semidirigidas y aplicación del procedimiento de dibujo-cuento con el tema “Vaginismo”. En este trabajo se destaca el análisis de los dibujos y cuentos por la riqueza de este instrumento. El material fue interpretado en conjunto, posibilitando la construcción de tres categorías temáticas: “Representaciones: el vaginismo como protagonista”, “El curso y la historia de la vida: los diferentes momentos del vaginismo” y “La soledad y las relaciones”. Los resultados apuntaron a diferentes percepciones del vaginismo según el tiempo de tratamiento, destacando la larga duración de los síntomas y el arduo proceso de convivencia con este trastorno. vida empírica cualitativa exploratoria dibujocuento dibujo cuento Vaginismo. Vaginismo . “Vaginismo” instrumento conjunto temáticas Representaciones “Representaciones protagonista, protagonista , protagonista” La relaciones. relaciones relaciones” tratamiento trastorno “Vaginismo

Abstract Considering that sexual dysfunction profoundly affects self-perception and quality of life, this study aims to understand the experience of living with vaginismus. This is an empirical, qualitative, exploratory research, in which nine women diagnosed with vaginismus at some point in their lives participated. Data were collected through individual semi-directed interviews and application of the drawing and story procedure with the theme “Vaginismus”. In this paper, the analysis of the drawings and stories is highlighted due to the richness of this instrument. The material was interpreted together, enabling the construction of three thematic categories: “Representations: vaginismus as a protagonist”, “The course and history of life: the different moments of vaginismus” and “Loneliness and relationships”. The results pointed to different perceptions of vaginismus according to the time of treatment, highlighting the long duration of symptoms and the arduous process of living with this disorder. selfperception self perception life empirical qualitative research participated semidirected semi directed Vaginismus. Vaginismus . “Vaginismus” paper instrument together categories Representations “Representations protagonist, protagonist , protagonist” Loneliness relationships. relationships relationships” treatment disorder “Vaginismus

Resumo Considerando que experienciar uma disfunção sexual afeta profundamente a autopercepção e a qualidade de vida, este estudo almejou compreender a experiência de viver com vaginismo. Trata-se de uma pesquisa empírica, qualitativa, de caráter exploratório, em que participaram nove mulheres diagnosticadas em algum período da vida com vaginismo. Os dados foram coletados por meio de entrevistas semidirigidas e do procedimento de desenhos-estórias com o tema “Vaginismo”, sendo que, neste trabalho, destaca-se a análise dos desenhos e histórias devido à riqueza deste instrumento. O material foi interpretado em conjunto possibilitando a construção de três categorias temáticas: “Representações: o vaginismo como protagonista”, “O percurso e a história de vida: os diferentes momentos do vaginismo” e “A solidão e os relacionamentos”. Os resultados apontaram para diferentes percepções do vaginismo de acordo com o momento do tratamento, destacando-se a longa duração dos sintomas e o árduo processo de viver com esta disfunção. Tratase Trata se empírica qualitativa exploratório desenhosestórias estórias Vaginismo, Vaginismo , “Vaginismo” trabalho destacase destaca instrumento temáticas Representações “Representações protagonista, protagonista protagonista” A relacionamentos. relacionamentos . relacionamentos” tratamento destacandose destacando “Vaginismo

Resumén En este texto pretendemos reflexionar, a través del entrelazamiento entre el concepto de dispositivo de racialidad (Carneiro, 2023) - como elemento estructurante del campo social - y la constitución del sujeto - tal como lo formula la teoría lacaniana - sobre la formación del brasileño subjetividad y, más específicamente, la producción de enfermedad y sufrimiento psicológico entre la población negra. Paralelamente, intentaremos señalar el concepto de ética radical de la escucha (Silva, 2019) y el concepto de autocuidado (desde la perspectiva de Carneiro [2023], basado en Foucault [2002]) como herramientas y estrategias para afrontamiento del dolor sentimientos subjetivos producidos por el racismo y la desigualdad socioeconómica. De esta manera, pretendemos resaltar la importancia de pensar la política pública de salud mental teniendo en cuenta la centralidad de las cuestiones raciales, de género, de clase y territoriales en la organización social de Brasil y en la producción de subjetividad, de sufrimiento, pero también de alternativas y soluciones. reflexionar Carneiro, (Carneiro 2023 específicamente negra Paralelamente Silva, Silva (Silva 2019 desde 2023, , [2023] 2002 [2002] socioeconómica manera raciales género soluciones 202 201 [2023 200 [2002 20 [202 [200 2 [20 [2 [

Abstract Through the concept of racial device (Carneiro, 2023), - as a structuring element of the social field - and the constitution of the subject - as formulated in Lacanian theory - we intend to reflect in this text on the formation of Brazilian subjectivity and, more specifically, on the production of illness and psychological suffering among the black population. In parallel, we will try to point out the concept of the radical ethics of listening (Silva, 2019) and the concept of self-care (from the perspective of Carneiro, 2023, based on Foucault, 2002) as tools and strategies for coping with the subjective feelings produced by racism and socio-economic inequality. In this way, we intend to highlight the importance of thinking about public mental health policies in light of the centrality of issues of race, gender, class, and territory in the social organization of Brazil and in the production of subjectivity, suffering, but also alternatives and solutions. Carneiro (Carneiro 2023 , 2023) specifically population parallel Silva, Silva (Silva 2019 selfcare self care from Foucault 2002 socioeconomic socio economic inequality way race gender class solutions 202 201 200 20 2

Resumo Neste texto pretendemos refletir, por meio do entrelaçamento entre o conceito de dispositivo de racialidade (Carneiro, 2023) - como elemento estruturante do campo social - e a constituição do sujeito - tal como formulada na teoria lacaniana - sobre a formação da subjetividade brasileira e, mais especificamente, a produção de adoecimento e sofrimento psíquico da população negra. Ao lado disso, intentaremos apontar o conceito de ética radical da escuta (Silva, 2019) e o conceito de cuidado de si (na perspectiva de Carneiro, 2023, a partir de Foucault, 2002) como ferramentas e estratégias de enfrentamento às dores subjetivas produzidas pelo racismo e pela desigualdade socioeconômica. Por essa via, pretendemos sublinhar a importância de se pensar a política pública de saúde mental levando em consideração a centralidade da questão racial, de gênero, de classe e de território na organização social do Brasil e na produção de subjetividade, de sofrimentos, mas também de alternativas e soluções. refletir Carneiro (Carneiro 2023 especificamente negra disso Silva, Silva (Silva 2019 Foucault 2002 socioeconômica via racial gênero sofrimentos soluções 202 201 200 20 2