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ABSTRACT Background: Helicobacter pylori (H. pylori) is a gram-negative bacterium associated with the etiology of several gastrointestinal tract pathologies, and cagA-positive (cagA+) strains are found in populations with gastric ulcers and precancerous lesions, inducing pro-inflammatory responses. The development of neoplasms is related to microRNA (miRNA) dysregulation, indicating highly expressed miRNA-629. The article aims to correlate the expression level of miRNA-629 with the presence of H. pylori and the pathogenicity marker cagA. Methods: 203 gastric biopsy samples were evaluated from individuals with normal gastric tissue (n=60), gastritis (n=96), and gastric cancer (n=47) of both genders and over 18 years old. The samples were subdivided according to the presence or absence of H. pylori, detected by polymerase chain reaction (PCR). RNA was extracted using a commercial kit and quantified. Complementary DNA (cDNA) was synthesized using commercial kits, and the relative expression was calculated using the 2-ΔΔCt method. Results: Individuals infected with H. pylori are nine times more likely to develop gastric cancer. Cancer patients appeared to have decreased expression of miRNA-629; however, the presence of the bacterium would not influence this reduction. Individuals in the cancer group showed lower miRNA-629 expression when cagA+; however, in the control group, the expression was higher when cagA+. Conclusion: H. pylori is a factor involved in the etiology and progression of gastric diseases. Reduction in miRNA-629 expression in cancer patients occurs independent of the presence of the bacterium, but when the cagA pathogenicity marker is present, it induces changes in the gene expression of the respective miRNA. Background H (H gramnegative gram negative pathologies cagApositive positive cagA+ (cagA+ lesions proinflammatory pro inflammatory responses miRNA (miRNA dysregulation miRNA629. miRNA629 629. 629 miRNA-62 Methods 20 n=60, n60 n n=60 , 60 (n=60) n=96, n96 n=96 96 (n=96) n=47 n47 47 (n=47 1 old PCR. PCR . (PCR) quantified cDNA (cDNA kits 2ΔΔCt ΔΔCt 2 method Results however reduction Conclusion diseases present (cagA miRNA62 62 miRNA-6 n6 n=6 6 (n=60 n9 n=9 9 (n=96 n=4 n4 4 (n=4 (PCR miRNA6 miRNA- n= (n=6 (n=9 (n= (n

RESUMO Contexto: Helicobacter pylori (H. pylori) é uma bactéria gram-negativa associada à etiologia de várias patologias do trato gastrointestinal, e cepas positivas para cagA (cagA+) são encontradas em populações com úlceras gástricas e lesões pré-cancerígenas, induzindo respostas pró-inflamatórias. O desenvolvimento de neoplasias está relacionado à desregulação do microRNA (miRNA), indicando miRNA-629 altamente expresso. O artigo tem como objetivo correlacionar o nível de expressão do miRNA-629 com a presença de H. pylori e o marcador de patogenicidade cagA. Métodos: Foram avaliadas 203 amostras de biópsia gástrica de indivíduos com tecido gástrico normal (n=60), gastrite (n=96) e câncer gástrico (n=47) de ambos os sexos e com mais de 18 anos. As amostras foram subdivididas de acordo com a presença ou ausência de H. pylori, detectado por reação em cadeia da polimerase (PCR). O RNA foi extraído usando um kit comercial e quantificado. O DNA complementar (cDNA) foi sintetizado usando kits comerciais, e a expressão relativa foi calculada usando o método 2-ΔΔCt. Resultados: Indivíduos infectados com H. pylori têm nove vezes mais chances de desenvolver câncer gástrico. Pacientes com câncer parecem ter diminuição da expressão do miRNA-629; no entanto, a presença da bactéria não influenciaria essa redução. Indivíduos no grupo do câncer apresentaram menor expressão do miRNA-629 quando cagA+; no entanto, no grupo controle, a expressão foi maior quando cagA+. Conclusão: H. pylori é um fator envolvido na etiologia e progressão das doenças gástricas. A redução na expressão do miRNA-629 em pacientes com câncer ocorre independentemente da presença da bactéria, mas quando o marcador de patogenicidade cagA está presente, induz mudanças na expressão gênica do respectivo miRNA. Contexto H (H gramnegativa gram negativa gastrointestinal cagA+ (cagA+ précancerígenas, précancerígenas pré cancerígenas, cancerígenas pré-cancerígenas próinflamatórias. próinflamatórias pró inflamatórias. inflamatórias pró-inflamatórias miRNA, miRNA , (miRNA) miRNA629 629 miRNA-62 expresso Métodos 20 n=60, n60 n n=60 60 (n=60) n=96 n96 96 (n=96 n=47 n47 47 (n=47 1 anos PCR. PCR . (PCR) quantificado cDNA (cDNA comerciais 2ΔΔCt. 2ΔΔCt ΔΔCt 2 ΔΔCt. 2-ΔΔCt Resultados entanto controle Conclusão presente (cagA (miRNA miRNA62 62 miRNA-6 n6 n=6 6 (n=60 n=9 n9 9 (n=9 n=4 n4 4 (n=4 (PCR miRNA6 miRNA- n= (n=6 (n= (n

https://doi.org/10.1590/s0004-2803.24612023-139

Avaliação do desconforto sensorial causado por estimulação com realidade virtual em voluntários com e sem cinetose
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Chun, Gabriel Yong Chul

; Neves, Newton Soares de Sá

; Fortes, Cleiton Carvalho

; Nishino, Lucia Kazuko

; Santos, Mônica Alcantara de Oliveira

Audiology - Communication Research

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2023, Volume 28 elocation e2680

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo comparar os sintomas da cinetose provocados por estímulo de realidade virtual, em voluntários com e sem histórico da doença. Métodos estudo analítico qualitativo e quantitativo, observacional transversal, prospectivo, realizado com voluntários com e sem histórico de cinetose, submetidos à imersão em realidade virtual com o uso de óculos de realidade aumentada. Antes e após a estimulação sensorial, o participante tinha a frequência respiratória (FR), a frequência cardíaca (FC) e pressão arterial sistólica (PAs) e diastólica (PAd) medidas. No primeiro dia, o voluntário foi exposto a um vídeo que simulava uma pessoa dentro de um carro, com predomínio de fluxo visual lateral. Após uma semana, uma animação de montanha russa, com predomínio de fluxo visual frontal. Durante a estimulação sensorial de dez minutos, uma nota de 0 a 10 era dada a cada 30 segundos para a intensidade do desconforto sentido pelo participante. Após, um questionário foi realizado para avaliação dos sintomas de cinetose. Resultados indivíduos com cinetose apresentaram maior intensidade de sintomas, tanto no experimento do carro (p=0,026), como na montanha russa (p=0,035). Não houve correlação entre cinetose e as variáveis FC, FR e PA. Os pacientes com cinetose atribuíram maiores notas de desconforto no curso das experiências, principalmente na experiência da montanha russa. Conclusão indivíduos com cinetose apresentam sintomas mais intensos quando submetidos a estímulos por realidade virtual, se comparados a indivíduos sem a doença.

ABSCTRACT Purpose to compare the symptoms of motion sickness caused by virtual reality stimulation in volunteers with and without history of the disease. Methods qualitative and analytical, observational, cross-sectional, and prospective study, approved by Research Ethics Committee, 3.443.429/19, with volunteers with and without history of motion sickness who were subjected to immersion in VR with the use of virtual reality glasses. Before and after sensory stimulation, the participant had respiratory rate (RF), heart rate (HR) and systolic blood pressure (PAs) and diastolic blood pressure (PAd) measured. On the first day, the volunteer was exposed to a video that simulated a person in a car, with a predominance of lateral visual flow. A week later, an animation of a roller coaster, with a predominance of frontal visual flow. During the 10-minute experiment, a score from 0 to 10 was given every 30 seconds for the intensity of the discomfort felt by the volunteer. A post-questionnaire was conducted to assess motion sickness symptoms. Results individuals with motion sickness history had a higher intensity of symptoms in the car (p = 0.026) and roller coaster experiment (p = 0.035). There was no correlation between motion sickness and the variables HR,FR,PA. Patients with motion sickness gave higher scores of discomfort throughout the experiments, mainly in the roller coaster experience. Conclusion individuals with motion sickness present more intense symptoms when subjected to stimuli by VR compared to controls without disease.

https://doi.org/10.1590/2317-6431-2022-2680pt

A Biodegradable Composite of Poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) with Short Cellulose Fiber for Packaging 3hydroxybutyrateco3hydroxyvalerate hydroxybutyratecohydroxyvalerate 3 hydroxybutyrate co hydroxyvalerate (3-hydroxybutyrate-co-3-hydroxyvalerate PHBV (PHBV hydroxybutyrateco
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Conceição, Marceli N.

; Santos, Mônica C.C. dos

; Mancipe, Javier M.A.

; Pereira, Patricia S.C.

; Ribeiro, Roberto C.C.

; Thiré, Rossana M.S.M.

; Bastos, Daniele C.

Materials Research

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2023, Volume 26 Suppl. 1 elocation e20220615

Abstract: En | Text: En | PDF: En

The problem of improper disposal of polymeric waste is increasingly in present. Thus, the use of biodegradable polymers is a good alternative, especially for packaging. Compostable and biodegradable polymers such as PHBV can be completely degraded, making them ideal. But the short processability window and fluid instability is an important drawback to the wider application of this polymer in pure form. Production of composite materials has been indicated as a possibility for using this polymer. One source of filler is cellulose, because besides being widely available from agroindustrial waste. In this context, the present work reports the formulation of rigid packaging with PHBV and cellulose waste. An analytical mill was used to promote the dispersion of cellulose fibers. In general, the cellulose fibers increased the Vicat softening point of the polymeric matrix. There were more crystalline structures, according to DSC, and a decrease in impact strength, probably due to increased crystallinity and agglomerate formation. The microscopic analysis indicated greater surface roughness of the composite due to the increase of fibers, resulting in increased contact angle. Thus alternative degraded ideal form context general matrix structures DSC strength formation angle

https://doi.org/10.1590/1980-5373-mr-2022-0615

Multisystem inflammatory syndrome (MIS-C): a systematic review and meta-analysis of clinical characteristics, treatment, and outcomes
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Santos, Mônica O.

; Gonçalves, Lucas C.

; Silva, Paulo A.N.

; Moreira, André L.E.

; Ito, Célia R.M.

; Peixoto, Fernanda A.O.

; Wastowski, Isabela J.

; Carneiro, Lilian C.

; Avelino, Melissa A.G.

Jornal de Pediatria

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jul 2022, Volume 98 N. 4 Pages 338 - 349

Abstract: En | Text: En | PDF: En

Abstract Objective: The clinical cases of patients with multisystem inflammatory syndrome (MIS-C) were analyzed via a systematic review and meta-analysis of the clinical findings, treatments, and possible outcomes of articles retrieved via database searches. Sources: The authors searched the PubMed, Scielo, Web of Science, Science Direct, EMBASA, EBSCO, and Scopus databases for articles containing the keywords “multisystem inflammatory syndrome in children” or “MIS-C” or “PIMS-TS” or “SIMP” and “COVID-19” or “SARS-CoV-2” published between December 1st, 2019 and July 10th, 2021. Patient characteristics, tissue and organ comorbidities, the incidence of symptoms after COVID-19 infection, treatment, and patient evolution in the articles found were evaluated. The data were abstracted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and Newcastle-Ottawa Scale (NOS). Findings: In total, 98 articles (2275 patients) were selected for demographics, clinical treatment, and outcomes of patients diagnosed with MIS-C. The average age of children with MIS-C, 56.8% of whom were male, was of nine years. Fever (100%), gastrointestinal (GI) (82%), and abdominal pain (68%) were the decisive symptoms for the diagnosis of MIS-C. Shock and/or hypotension were common in patients with MIS-C. Cardiac symptoms (66%) predominated over respiratory (39%) and neurological (28%) symptoms. MIS-C treatment followed the common guidelines for treating children with septic shock and Kawasaki disease (KD) and proved to be effective. Conclusions: This meta-analysis highlights the main clinical symptoms used for the diagnosis of MIS-C, the differences between MIS-C and KD, and the severity of the inflammatory process and urgency for hospital care.

https://doi.org/10.1016/j.jped.2021.08.006

Evidências de Validade do Inventário de Compensação de Young (YCI) para a População do Rio Grande do Sul
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Santos, Mônica Benedetti dos

; Machado, Wagner de Lara

; Ávila, Andressa Celente de

; Oliveira, Margareth da Silva

Psico-USF

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jun 2022, Volume 27 N. 2 Pages 331 - 343

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo O objetivo deste estudo foi examinar a estrutura fatorial e as evidências de validade do Inventário de Compensação de Young (YCI) para a população do Rio Grande do Sul. Contou-se com a participação de 504 adultos da população geral, com média de idade de 34,2 anos (DP = 12,9). Os instrumentos utilizados foram o Questionário de Esquemas de Young - Versão Breve (YSQ-S3), a Escala de Avaliação dos Sintomas (SCL-90-R) e o YCI. Os dados foram coletados através de plataforma online. Realizou-se a análise fatorial exploratória, para verificar a distribuição dos itens em fatores comuns, e a validade convergente, com correlação não paramétrica de Spearman com a SCL-90-R e o YSQ-S3. Foram interpretados quatro fatores: Dominação e Manipulação (α =0,85 ω=0,71); Obsessão e Organização (α =0,75 ω=0,75); Rebeldia e Independência (α =0,73 ω=0,69); e Busca de Reconhecimento (α =0,81 ω=0,91). A validade de construto mostrou-se adequada conforme a teoria. Concluiu-se que a versão adaptada apresenta boas propriedades psicométricas.

Abstract This study aimed to examine the factorial structure and evidence of validity of the Young Compensation Inventory (YCI) for the population of the state of Rio Grande do Sul. For this purpose, 504 adults from the general population participated, with a mean age of 34.2 years (SD = 12.9). The instruments used were the Young Schema Questionnaire - Brief Version (YSQ-S3), the Symptom Checklist-90 (SCL-90-R), and the YCI. Data were collected using an online platform. Exploratory factor analysis was performed to verify the distribution of items in common factors, and convergent validity, with a non-parametric Spearman correlation with SCL-90-R and YSQ-S3. Four factors were interpreted: Domination and Manipulation (α = 0.85 ω = 0.71); Obsession and Organization (α = 0.75 ω = 0.75); Rebellion and Independence (α = 0.73 ω = 0.69); and Search for Recognition (α = 0.81 ω = 0.91). The result of construct validity proved to be adequate according to the theory. It was concluded that the adapted version has good psychometric properties.

Resumen El objetivo de este estudio fue examinar la estructura factorial y las evidencias de validez del Young Compensation Inventory (YCI) para la población de Rio Grande do Sul. Participaron 504 adultos de la población general, con una edad media de 34,2 años (DS = 12,9). Los instrumentos utilizados fueron el Young Scheme Questionnaire - Versión breve (YSQ-S3), la Escala de Evaluación de Síntomas (SCL-90-R) y el YCI. Los datos se recogieron a través de una plataforma online. Se realizó un análisis factorial exploratorio para verificar la distribución de los ítems en factores comunes, y la validez convergente, con la correlación no paramétrica de Spearman con SCL-90-R y YSQ-S3. Se interpretaron cuatro factores: Dominación y Manipulación (α =0,85 ω=0,71); Obsesión y Organización (α =0,75 ω=0,75); Rebeldía e Independencia (α =0,73 ω=0,69); y Búsqueda de Reconocimiento (α =0,81 ω=0,91). La validez de constructo demostró ser adecuada según la teoría. Se concluyó que la versión adaptada presenta buenas propiedades psicométricas.

https://doi.org/10.1590/1413-82712022270210

Analysis of wideband tympanometry in Ménière’s disease
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Tanno, Gisela Andrea Yamashita

; Santos, Mônica Alcantara de Oliveira

; Sanches, Marcelo Tabosa Dutra

; Durante, Alessandra Spada

; Almeida, Kátia de

; Gameiro, Marcella Scigliano

; Roque, Nayara Michelle Costa de Freitas

; Sousa Neto, Osmar Mesquita de

Brazilian Journal of Otorhinolaryngology

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apr 2022, Volume 88 N. 2 Pages 194 - 203

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: A hidropsia endolinfática é o substrato fisiopatológico da doença de Ménière. As alterações desencadeadas na orelha interna, transmitidas à orelha média pelas modificações na mobilidade da cadeia ossicular, podem ser quantificadas pela timpanometria de banda larga, através da medida da absorvância acústica sob múltiplas frequências, representadas pela energia sonora absorvida pela orelha média, mesmo em estágios iniciais de sua instalação. Estudar o comportamento da orelha média através da absorvância em pacientes com hidropisia endolinfática sob pressão ambiente e sob o pico de pressão pode ser útil na detecção da doença de Ménière. Objetivo: Caracterizar o comportamento da absorvância em indivíduos com diagnóstico da doença de Ménière sintomáticos e assintomáticos, comparados com controles, a fim de verificar a capacidade da timpanometria de banda larga em detectar variações clínicas relacionadas a possível hidropisia endolinfática. Método: Foi realizado um estudo transversal, com enfoque diagnóstico, que comparou os achados da timpanometria de banda larga na pressão ambiente e no pico de pressão entre orelhas do grupo controle (n = 30), grupo assintomático (n = 21) e grupo sintomático (n = 9). Resultados: Foram encontrados valores do pico de pressão diferentes entre orelhas do grupo controle (0 daPa), do grupo assintomático (-11 daPa) e do grupo sintomático (-192 daPa), com p <0,05 pelos testes de Kruskal-Wallis, Mann Whitney e correção de Bonferroni. Foram encontrados valores de absorvância diferentes entre orelhas do grupo sintomático e do grupo assintomático em relação ao grupo controle para as frequências baixas na pressão ambiente e na pressão de pico, com p < 0,05 pelos testes de Kruskal-Wallis, Mann Whitney e correção de Bonferroni. Conclusão: A timpanometria de banda larga foi um teste capaz de identificar a presença da doença de Ménière e de diferenciar os pacientes assintomáticos e sintomáticos, comparando-os com indivíduos hígidos.

Abstract Introduction: Endolymphatic hydrops is the pathophysiological substrate of Ménière’s disease. The changes in the inner ear, transmitted to the middle ear through changes in the ossicular chain mobility, can be quantified by wideband tympanometry, through the measurement of the acoustic absorbance at multiple frequencies, represented by the sound energy absorbed by the middle ear, even at its early stages. Studying the behavior of the middle ear through the absorbance in patients with endolymphatic hydrops under ambient pressure and under peak pressure can be useful for detecting Ménière’s disease. Objective: To characterize acoustic absorbance behavior in subjects with symptomatic and asymptomatic Ménière’s disease compared to controls, in order to verify the ability of wideband tympanometry to detect Ménière’s disease. Methods: We carried out a cross-sectional study with a diagnostic approach comparing the findings of wideband tympanometry at ambient pressure and peak pressure between the ears of the control group (n = 30), the asymptomatic group (n = 21) and the symptomatic group (n = 9). Results: Different peak pressure values were found between the ears of the control group (0daPa), the asymptomatic group (−11 daPa) and the symptomatic group (−192 daPa), with p < 0.05 by the Kruskal-Wallis test, Mann Whitney test and Bonferroni correction. Different absorbance values were found between the ears of the symptomatic group and the asymptomatic group compared to the control group for low frequencies at ambient pressure and peak pressure, with p < 0.05 by the Kruskal-Wallis test, Mann Whitney test and Bonferroni correction. Conclusions: The Wideband Tympanometry test was capable of identifying the presence of Ménières disease, and to differentiate between asymptomatic and symptomatic patients, when comparing them with healthy individuals.

https://doi.org/10.1016/j.bjorl.2020.05.029

Uso da posturografia para identificação do risco de queda em idosos com tontura
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Leopoldo, Caroline Martins dos Santos

; Nishino, Lucia Kazuko

; Santos, Mônica Alcantara de Oliveira

Audiology - Communication Research

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2022, Volume 27 elocation e2684

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo avaliar se a posturografia, exame que avalia a habilidade de manter o equilíbrio em condições sensoriais conflitantes, pode identificar risco de queda em idosos com tontura. Métodos comparar os resultados posturográficos de idosos com e sem história de quedas, pareados por gênero, idade e diagnóstico etiológico da tontura. Resultados dezoito idosos com quedas – 4 com único episódio e 14 com história de 2 ou mais quedas no último ano - foram comparados com 18 idosos sem quedas, pareados por gênero, idade e diagnóstico etiológico. Pacientes com quedas apresentaram resultados piores para as análises de dependência visual (p=0,04, p=0,01, p=0,03). Pacientes com quedas recorrentes (2 ou mais episódios) apresentaram piores resultados em diversas condições sensoriais: somatossensorial, vestibular, dependências visuais e índice de equilíbrio composto. Conclusão a posturografia mostrou-se útil na identificação de idosos com quedas, principalmente em indivíduos com quadros recorrentes.

ABSTRACT Purpose the aim of this study is to determine whether posturography, an exam used to investigate the ability to maintain balance under conflicting sensory conditions, can identify the risk of falls in eldery patients with dizziness. Methods to compare the posturographic results of elderly people with falls vs elderly people with no falls, paired by sex, age and dizziness etiology. Results 18 fallers, and, of these, 14 with two or more falls in the last year were compared with 18 elderly people without falls. Comparing subjects without falls vs subjects with at least one fall in the last year, fallers obtain worse scores in conditions of visual dependence. Comparing non fallers with subjects with two or more falls, people with recurrent falls obtain worse score in several conditions: somatosensorial, vestibular, visual conflict, and in the main measure, the composite score. Conclusion posturography appears to be a useful tool to identify those at high risk of recurrent falls.

https://doi.org/10.1590/2317-6431-2022-2684pt

Main etiological agents identified in 170 men with urethritis attended at the Fundação Alfredo da Matta, Manaus, Amazonas, Brazil,
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de Souza, Lucilene Sales

; Sardinha, José Carlos

; Talhari, Sinésio

; Heibel, Marcel

; Santos, Mônica Nunes dos

; Talhari, Carolina

Anais Brasileiros de Dermatologia

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mar 2021, Volume 96 N. 2 Pages 176 - 183

Abstract: En | Text: En | PDF: En

Abstract Background: Sexually transmitted infections (STI) are a global public health problem. Urethritis are among the most common STIs, and can cause several complications and facilitate the transmission of the HIV virus. Objectives: To investigate the main etiologic agents of urethritis in 170 men treated at Fundação Alfredo da Matta. Methods: To identify the agents, urethral exudate and urine were collected. Gram and culture tests were performed in Thayer-Martin medium for Neisseria gonorrhoeae and polymerase chain reaction for Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis, Ureaplasma urealyticum, Ureaplasma parvum, Mycoplasma hominis, Mycoplasma genitalium, and herpes simplex types 1 and 2. Results: N. gonorrhoeae were identified in 102 (60.0%) patients, C. trachomatis in 50 (29.4%), U. urealyticum in 29 (17.0%), M. genitalium in 11 (6.5 %), U. parvum in ten (5.9%), and M. hominis in seven (4.1%). Herpes simplex type 2 was diagnosed in 24 (21.6%) of the 111 patients who underwent PCR for this pathogen. In 69 cases there was co-infection; the most frequent were: N. gonorrhoeae and C. trachomatis in 21 (14.7%) patients; N. gonorrhoeae and C. trachomatis in 21 (12.4%) patients; N. gonorrhoeae and herpes simplex type 2 in 11 (6.5%), and N. gonorrhoeae and U. urealyticum in nine (5.3%). Study limitations: Not relevant. Conclusion: N. gonorrhoeae, C. trachomatis, U. urealyticum, and herpes simplex type 2 were the pathogens most frequently identified in the present study. The main coinfection found was N. gonorrhoeae and C. trachomatis. T. vaginalis and herpes simplex type 1 were not identified in any of the patients.

https://doi.org/10.1016/j.abd.2020.07.007 167 downloads

Atenção à pessoa com deficiência: composição das equipes e distribuição geográfica do componente especializado em reabilitação
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Santos, Mônica Farina Neves

; Friche, Amélia Augusta Lima

; Lemos, Stela Maris Aguiar

CoDAS

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2021, Volume 33 N. 1 elocation e20190184

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo analisar a composição das equipes e a distribuição geográfica dos serviços e profissionais da Rede de Cuidados à Pessoa com Deficiência (RCPD). Método estudo observacional-analítico-transversal, desenvolvido por meio de dados secundários do componente especializado em reabilitação, com amostra de 3.271 profissionais. Resultados a metade dos serviços está em três regiões ampliadas; há maior representação de Serviços Especializados em Reabilitação da Deficiência Intelectual (SERDI), serviços privados e fisioterapeutas; observou-se que a maioria dos serviços possui equipes completas e que a maior parte não cumpre carga horária mínima estabelecida pela política nacional; as regiões ampliadas Jequitinhonha, Norte e a modalidade Centros Especializados em Reabilitação (CER) apresentaram maiores médias de profissionais e carga horária; houve associação estatisticamente significante entre equipe completa e serviços privados. Conclusão os resultados podem contribuir no desenvolvimento de estratégias que minimizem as disparidades encontradas na distribuição geográfica, nas modalidades de reabilitação e nos investimentos para rede pública.

ABSTRACT Purpose to analyze the composition of teams and the geographical distribution of the services and professionals of the Health Care Network for People with Disabilities (RCPD, initials in Portuguese). Methods cross-sectional observational study developed from secondary data on the specialized component in rehabilitation, with a sample of 3,271 professionals. Results half of the services was observed in three broad regions; there is a greater representation of Specialized Services in Intellectual Disability Rehabilitation (SERDI, initials in Portuguese), private services and physiotherapists. We observed that most services had full teams; however, most of them do not comply with the minimum workload established by national policy. The Enlarged Health Regions of Jequitinhonha, Norte and the Centros Especializados em Reabilitação (CER, initials in Portuguese) modality presented the highest averages in terms of professionals and workload. Our results show a significant statistical association between full teams and private services. Conclusion these results have the potential to contribute to the development of strategies to minimize the disparities found in the geographical distribution, in rehabilitation modalities, and public service investments.

https://doi.org/10.1590/2317-1782/20202019184 469 downloads

10.

Endoscopy infection control strategy during the COVID-19 pandemic: experience from a tertiary cancer center in Brazil
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Pombo, Amanda A.M.

; Lenz, Luciano

; Paulo, Gustavo A.

; Santos, Mônica A.

; Tamae, Patricia K.

; Santos, Alisson L.D.R.

; Rezende, Daniel T.

; Martins, Bruno

; Kawaguti, Fabio S.

; Pennachi, Caterina M.P.S.

; Gusmon-Oliveira, Carla C.

; Uemura, Ricardo S.

; Geiger, Sebastian

; Lima, Marcelo S.

; Baba, Elisa R.

; Figueiredo, Viviane R.

; Safatle-Ribeiro, Adriana

; Maluf-Filho, Fauze

; Ribeiro-Júnior, Ulysses

Clinics

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2021, Volume 76 elocation e2280

Abstract: En | Text: En | PDF: En

OBJECTIVES: Strategic planning for coronavirus disease (COVID-19) care has dominated the agenda of medical services, which have been further restricted by the need for minimizing viral transmission. Risk is particularly relevant in relation to endoscopy procedures. This study aimed to describe a contingency plan for a tertiary academic cancer center, define a strategy to prioritize and postpone examinations, and evaluate the infection rate among healthcare workers (HCWs) in the endoscopy unit of the Cancer Institute of the State of São Paulo (ICESP). METHODS: We created a strategy to balance the risk of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and to mitigate the effects of postponing endoscopic procedures in oncological patients. A retrospective analysis of prospectively collected data on all endoscopies between March and June 2020 compared with those during the same period in 2019 was carried out. All HCWs were interviewed to obtain clinical data and SARS-CoV-2 test results. RESULTS: During the COVID-19 outbreak, there was a reduction of 55% in endoscopy cases in total. Colonoscopy was the most affected modality. The total infection rate among all HCWs was 38%. None of the senior digestive endoscopists had COVID-19. However, all bronchoscopists had been infected. One of three fellows had a serological diagnosis of COVID-19. Two-thirds of all nurses were infected, whereas half of all technicians were infected. CONCLUSIONS: In this pandemic scenario, all endoscopy services must prioritize the procedures that will be performed. It was possible to maintain some endoscopic procedures, including those meant to provide nutritional access, tissue diagnosis, and endoscopic resection. Personal protective equipment (PPE) seems effective in preventing transmission of COVID-19 from patients to digestive endoscopists. These measures can be useful in planning, even for pandemics in the future.

https://doi.org/10.6061/clinics/2021/e2280 501 downloads

11.

Dance, Bravo! Magazine, the Education of the Public: cultural reverberations of pedagogical ideas
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Santos, Mônica Evelyn dos

; Aquino, Julio Groppa

Revista Brasileira de Estudos da Presença

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2021, Volume 11 N. 4 elocation e109004

Abstract: Pt En Fr | Text: Pt En Fr | PDF: Pt | PDF: En | PDF: Fr

RESUMO Com o intuito de analisar os vínculos entre dança e educação segundo uma perspectiva que não se ativesse ao ensino de tal prática artística, a presente investigação focalizou as matérias sobre dança publicadas na revista cultural Bravo!, de 1997 a 2013. A partir da categorização de três grandes temas - o balé clássico e seu caráter disciplinar; os aspectos étnicos e populares na dança contemporânea brasileira; e a formação do público de dança -, a análise do material permitiu verificar a irrupção de um viés pedagogizante na discursividade da revista por meio da proliferação de uma série de imperativos voltados à educação do público consumidor da dança.

ABSTRACT In order to analyze the relationships between dance and education from a perspective not limited to teaching the artistic practice, this study examined articles on dance published in the cultural magazine Bravo! (1997 to 2013). From the categorization of three major themes - classical ballet and its disciplinary content; ethnic and popular aspects of Brazilian contemporary dance; and the building of an audience for dance - an analysis of the material verified the emergence of a pedagogical bias in the magazine’s discourse, expressed in a proliferation of imperatives aimed at educating the dance audience.

RÉSUMÉ Afin d’analyser les liens entre danse et éducation selon une perspective qui ne se limite pas à l’enseignement de cette pratique artistique, la présente recherche s’est focalisée sur les articles sur la danse publiés dans le magazine culturel Bravo! (1997 à 2013). À la suite de la catégorisation de trois thèmes majeurs - le ballet classique et son caractère disciplinaire; les aspects ethniques et populaires de la danse brésilienne contemporaine; et la formation du public de la danse -, l’analyse de la matière a permis de vérifier l’éruption d’un biais pédagogique dans le discours du magazine à travers la multiplication d’une série d’impératifs visant l’éducation du public consommateur de danse.

https://doi.org/10.1590/2237-2660109004 136 downloads

12.

Translation and cross-cultural adaptation of the NutriQoL® questionnaire to the Portuguese language: Brazilian version
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OLIVEIRA, João Paulo Lima de

; SANTOS, Mônica Sabrina Ribeiro dos

; MACHADO, Hellen Custódio

; AGUIAR, Sarah Leão Fiorini de

; FERREIRA, Lívia Garcia

Revista de Nutrição

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2021, Volume 34 elocation e200285

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo O intuito deste estudo foi realizar a tradução do NutriQoL para a língua portuguesa e a adaptação transcultural para o Brasil. Métodos O NutriQoL® é composto de 17 pares de perguntas que avaliam a qualidade de vida de pacientes em terapia nutricional enteral domiciliar. Os procedimentos metodológicos foram: tradução da versão em espanhol para a língua portuguesa por dois tradutores; síntese das traduções; retrotradução; avaliação, da versão traduzida, por um comitê de juízes composto por 24 indivíduos, na qual o índice de validade de conteúdo > 0,78 foi considerado, gerando a versão pré-final e realização de um pré-teste no qual a versão pré-final do questionário foi aplicada a 12 pacientes em uso de terapia nutricional enteral domiciliar para análise da equivalência semântica e elaboração da versão final do questionário. Resultados Observou-se que, a partir das duas versões traduzidas, foi possível obter uma versão síntese do questionário. As duas retrotraduções geradas foram idênticas em 73,6% das sentenças (n=25). O índice de validade de conteúdo foi 0,88 ± 0,11, e 14,7% (n=5) das questões tiveram baixo índice de validade de conteúdo, sendo então reformuladas. No pré-teste foi observado que 35,3% (n=12) dos itens obtiveram baixos índices de compreensão e necessitaram de ser reformulados. Na elaboração da versão final do questionário as inconsistências dos itens mencionados foram sanadas e/ou adaptadas. Conclusão Após conclusão dos procedimentos metodológicos, foi possível obter a versão brasileira do questionário NutriQoL® em língua portuguesa para que, após processo de validação, o instrumento seja utilizado pelo nutricionista ou demais profissionais de saúde para avaliação da qualidade de vida de pacientes em uso de terapia nutricional enteral domiciliar, a fim de contribuir com melhorias nas práticas assistenciais.

ABSTRACT Objective The objective of this study was to translate and cross-culturally adapt the NutriQoL® into Brazilian Portuguese. Methods The NutriQoL® comprises 17 questions that evaluate the quality of life of patients receiving home enteral nutrition therapy. The methodological procedures included the translation from the Spanish version into Portuguese by two translators, synthesis of the translations, back translation, evaluation by a committee of judges composed of 24 individuals in which a content validity index > 0.78 was considered acceptable, and generation of the pre-final version. A pre-test to analyze its semantic equivalence was administered to 12 patients receiving home enteral nutrition therapy. The final version of the questionnaire was then prepared. Results A summary version of the questionnaire was obtained using two versions of the translation. Both back translations were identical for 73.6% of sentences (n=25). Twenty-four volunteers were included in the committee of judges. The content validity index was 0.88±0.11, and 14.7% (n=5) of questions had a low content validity index and were thus reformulated. In the pre-test, 35.3% (n=12) of items obtained low levels of understanding and required adjustment. In the preparation of the final version, the inconsistencies of the items mentioned were corrected and/or adjusted. Conclusion After completing the methodological procedures, a Brazilian Portuguese version of the NutriQoL® questionnaire was obtained. Following the validation process, it can be used by dieticians and other health professionals to assess the quality of life of patients receiving home enteral nutrition therapy to contribute to improvements in care practices.

https://doi.org/10.1590/1678-9865202134e200285

13.

Effects of different hydration treatments on technological, physical, nutritional, and bioactive parameters of lentils
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Bragança, Guilherme

; Ávila, Bianca

; Rockenbach, Reni

; Santos, Magda

; Alves, Gabriela

; Santos, Mônica de los

; Bortolini, Vera

; Monks, Jander

; Peres, William

; Elias, Moacir

Revista chilena de nutrición

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aug 2020, Volume 47 N. 4 Pages 658 - 668

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Regular lentil consumption may improve health and prevent certain chronic diseases. Lentils have high antioxidant activity and contain proteins, essential amino acids, fiber, minerals, and bioactive compounds. However, few studies have investigated the physicochemical characteristics of lentils when subjected to various soaking and cooking methods. We aimed to evaluate the effects of different hydration and cooking practices on the hydration coefficient, cooking time, primary metabolism compounds (lipids, proteins, fibers, carbohydrates), energy value, soluble protein, color and texture characteristics, amino acid and mineral profiles, bioactive compounds, antioxidant activity, and antinutritional factors (phytates and tannins) in lentils. Hydration water was preheated to initial temperatures of 25°C or 90°C. Lentils pre-hydrated with water at 90°C needed less cooking time, obtained greater softness, and had less decreases in amino acids, minerals, bioactive compounds, and antioxidant activity.

RESUMEN El consumo regular de lentejas puede mejorar la salud y prevenir ciertas enfermedades crónicas. Las lentejas tienen una alta actividad antioxidante y contienen proteínas, aminoácidos esenciales, fibra, minerales y compuestos bioactivos. Sin embargo, pocos estudios han investigado las características fisicoquímicas de las lentejas sometidas a varios métodos de remojo y cocción. El objetivo de este estudio fue evaluar los efectos de diferentes procesos de cocción e hidratación sobre el coeficiente de hidratación, el tiempo de cocción, los metabolitos primarios (lípidos, proteínas, fibras, carbohidratos), el valor energético, la proteína soluble, color y textura, los perfiles de aminoácidos y minerales, los compuestos bioactivos, la actividad antioxidante y los factores antinutricionales (fitatos y taninos) en la lenteja. El agua de hidratación se precalentó a temperaturas iniciales de 25°C o 90°C. Las lentejas prehidratadas con agua a 90°C necesitaban menos tiempo de cocción y obtuvieron una mayor suavidad, disminuyendo también la pérdida de aminoácidos, minerales, compuestos bioactivos y actividad antioxidante.

600 downloads

14.

Neurotology: definitions and evidence-based therapies - Results of the I Brazilian Forum of Neurotology
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Salmito, Márcio Cavalcante

; Maia, Francisco Carlos Zuma e

; Gretes, Mário Edvin

; Venosa, Alessandra

; Ganança, Fernando Freitas

; Ganança, Maurício Malavasi

; Mezzalira, Raquel

; Bittar, Roseli Saraiva Moreira

; Gasperin, Alexandre Camilotti

; Pires, Anna Paula Batista de Ávila

; Ramos, Bernardo Faria

; Bertoldo, César

; Ferreira Jr., Cícero

; Real, Danilo

; Guimarães, Humberto Afonso

; Oiticica, Jeanne

; Lavinsky, Joel

; Lopes, Karen Carvalho

; Duarte, Juliana Antoniolli

; Morganti, Lígia Oliveira Gonçalves

; Santos, Lisandra Megumi Arima dos

; Joffily, Lúcia

; Lavinsky, Luíz

; Santos, Mônica Alcantara de Oliveira

; Mano, Patrícia Mauro

; Araújo, Pedro Ivo Machado Pires de

; Mangabeira Albernaz, Pedro Luís

; Cal, Renato

; Dorigueto, Ricardo Schaffeln

; Guimarães, Rita de Cássia Cassou

; Carvalho, Rogério Castro Borges de

Brazilian Journal of Otorhinolaryngology

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apr 2020, Volume 86 N. 2 Pages 139 - 148

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: A otoneurologia é uma área de conhecimento que tem se expandido muito rapidamente. O estudo do sistema vestibular tem avançado tanto que mesmo definições básicas, como o significado dos sintomas vestibulares, foram apenas recentemente padronizadas. Objetivo: Apresentar uma revisão dos principais assuntos da otoneurologia, inclusive conceitos, diagnóstico e tratamento da otoneurologia, definir a evidência científica atual para facilitar a tomada de decisões e demonstrar as áreas mais carentes de evidência para estimular novas pesquisas. Método: Este texto é fruto do I Fórum Brasileiro de Otoneurologia, que reuniu os principais pesquisadores brasileiros dessa área para uma revisão da literatura. Serão feitos três trabalhos de revisão a serem publicados. Este primeiro abordou as definições e as terapias, o segundo abordará as ferramentas diagnósticas e o terceiro definirá os principais diagnósticos. Cada autor fez um levantamento bibliográfico na base de dados da Lilacs, SciELO, Pubmed e Medline de um determinado assunto. O seu texto foi então submetido aos demais participantes do Fórum por 30 dias para análise. Um capítulo especial, da definição dos sintomas vestibulares, foi traduzido por serviço de tradução oficial e igualmente submetido às demais etapas do processo. Houve então uma reunião presencial em que todos os textos foram apresentados oralmente e houve uma discussão entre os participantes para a definição de um texto consensual para cada capítulo. Os textos consensuais foram então submetidos a uma revisão final por quatro professores de otoneurologia de três universidades brasileiras e, por fim, finalizado. A partir do texto completo, publicado no site da Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, foi escrita esta versão-resumo como artigo de revisão. Resultado: O texto apresenta a tradução oficial para o português da definição dos sintomas vestibulares propostos pela Barany Society e agrupa as principais evidências científicas para cada um das principais terapias existentes para as doenças otoneurológicas. Conclusão: Este texto agrupou de forma racional os principais tópicos de conhecimento a respeito das definições e terapias da otoneurologia, permite ao leitor uma visão ampla da abordagem dos pacientes otoneurológicos baseada em evidências científicas e experiência nacional, que deverá auxiliá-lo na tomada de decisões clínicas, e mostra os assuntos mais carentes de evidência para estimular novos estudos.

Abstract Introduction: Neurotology is a rapidly expanding field of knowledge. The study of the vestibular system has advanced so much that even basic definitions, such as the meaning of vestibular symptoms, have only recently been standardized. Objective: To present a review of the main subjects of neurotology, including concepts, diagnosis and treatment of Neurotology, defining current scientific evidence to facilitate decision-making and to point out the most evidence-lacking areas to stimulate further new research. Methods: This text is the result of the I Brazilian Forum of Neurotology, which brought together the foremost Brazilian researchers in this area for a literature review. In all, there will be three review papers to be published. This first review will address definitions and therapies, the second one will address diagnostic tools, and the third will define the main diseases diagnoses. Each author performed a bibliographic search in the LILACS, SciELO, PubMed and MEDLINE databases on a given subject. The text was then submitted to the other Forum participants for a period of 30 days for analysis. A special chapter, on the definition of vestibular symptoms, was translated by an official translation service, and equally submitted to the other stages of the process. There was then a in-person meeting in which all the texts were orally presented, and there was a discussion among the participants to define a consensual text for each chapter. The consensual texts were then submitted to a final review by four professors of neurotology disciplines from three Brazilian universities and finally concluded. Based on the full text, available on the website of the Brazilian Association of Otorhinolaryngology and Cervical-Facial Surgery, this summary version was written as a review article. Result: The text presents the official translation into Portuguese of the definition of vestibular symptoms proposed by the Bárány Society and brings together the main scientific evidence for each of the main existing therapies for neurotological diseases. Conclusion: This text rationally grouped the main topics of knowledge regarding the definitions and therapies of Neurotology, allowing the reader a broad view of the approach of neurotological patients based on scientific evidence and national experience, which should assist them in clinical decision-making, and show the most evidence-lacking topics to stimulate further study.

https://doi.org/10.1016/j.bjorl.2019.11.002 2736 downloads

15.

Direct Analysis of Human Hair Before and After Cosmetic Modification Using a Recent Data Fusion Method
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Santos, Mônica C.

; Pereira, Fabíola M. V.

Journal of the Brazilian Chemical Society

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jan 2020, Volume 31 N. 1 Pages 33 - 39

Abstract: En | Text: En | PDF: En

The cosmetic modification of hair is a very common procedure used to mask or cover evidence at a crime scene. Deoxyribonucleic acid (DNA) tests are expensive and require good-quality collection of samples and a database profile. To overcome these challenges, direct analysis was performed on a large set of hair strands collected from individuals, denoted original samples, and the data were compared with those of the same samples after cosmetic modification performed by bleaching the samples in the laboratory. A total of 127 samples were evaluated in this study using two analytical techniques, wavelength-dispersive X-ray fluorescence (WDXRF) and laser-induced breakdown spectroscopy (LIBS). Instead of testing many algorithms to develop classification models for the original and bleached samples, a recent method was applied that combines information from 17 classifiers. Data fusion was also evaluated to improve the accuracy of the classification model, which was higher than 99.2%, with no requirements to select eigenvectors or thresholds.

https://doi.org/10.21577/0103-5053.20190121 488 downloads

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