RESUMO: Objetivou-se com este estudo avaliar os efeitos do tratamento de cães com erliquiose monocítica canina (EMC) com cloridrato de doxiciclina associada ou não à prednisolona sobre o perfil hematológico e de proteínas séricas. Foram selecionados, na Clínica Médica de Pequenos Animais do Hospital Veterinário da Universidade Federal de Campina Grande (UFCG), 10 cães com EMC. O diagnóstico foi obtido através de exame clínico, hemograma e teste de imunoensaio imunocromatográfico (com anticorpos anti Ehrlichia canis). As amostras foram distribuídas aleatoriamente em dois grupos experimentais, com cinco animais cada (n=5), denominados GD e GDP. O grupo GD foi tratado com doxiciclina (5 mg/kg, VO, BID durante 28 dias) e o grupo GDP, tratado com doxiciclina na mesma dose e duração e prednisolona (2 mg/kg, VO, BID, durante 5 dias). Durante o período de tratamento, foram realizadas quatro coletas de sangue; uma coleta basal (M0), uma com 10 dias (M10), uma aos 21 dias (M21) e outra ao final do tratamento (M28). Dessas amostras foram realizados eritrograma, leucograma, plaquetograma e proteinograma (dosagem de proteínas totais, pré-albumina, albumina, α-1 globulina, α-2 globulina, ß-globulina, ɣ-globulina e proteína C-reativa) no Laboratório de Patologia Clínica do Hospital Veterinário da UFCG. Os resultados que apresentaram distribuição normal foram submetidos ao teste de Tukey (P<0,05). Ao comparar os tratamentos GD e GDP, observou-se que os dois promoveram resposta discreta e semelhante dos parâmetros hematológicos nos diferentes momentos. Os resultados obtidos permitem concluir que ambos os protocolos terapêuticos resultaram em melhora clínica e dos parâmetros hematológicos e do proteinograma. Porém, o uso da prednisolona na dose empregada durante os primeiros cinco dias de tratamento não demonstrou efeitos mais benéficos do que a administração isolada da doxiciclina.

ABSTRACT: The objective of the present study was to assess the treatment of dogs with ehrlichiosis (tropical canine pancytopenia (TCP)) with doxycycline hydrochloride associated or not with prednisolone on the hematological profile and serum proteins. Ten dogs with TCP were selected in the Small Animal Medical Clinic Veterinary Hospital, Federal University of Campina Grande-UFCG-PB, Brazil. The diagnosis was obtained by clinical examination, hemogram and immunochromatographic test (with anti Ehrlichia canis antibodies). Samples were distributed randomly in two experimental groups of five animals each (n = 5), named GD and GDP. The GD group was treated with doxycycline (5 mg/kg, VO, BID for 28 days) and the GDP group was treated with doxycycline at the same dose and duration and prednisolone (2 mg/kg, VO, BID, for five days). Four blood collections were made during the treatment period: a base collection (M0), one at 10 days (M10), a second at 21 days (M21) and another at the end of the treatment (M28). These samples were used for the tests erythrogram, leucogram, plateletgram and proteinogram (dose of total proteins, pre-albumin, albumin, albumin, α-1 globulin, α-2 globulin, ß-globulin, ɣ-globulin and C- reactive protein) in the Clinical Pathology Laboratory, Veterinary Hospital-UFCG-PB. Results, that presented normal distribution, was submitted to the Tukey test (P<0.05). Comparison of treatments GD and GDP showed that both promoted discreet and similar response in the hematological parameters at different times. Results obtained allowed the conclusion that both therapeutic protocols resulted in clinical, hematological parameter and proteinogram improvement, but the use of prednisolone at the dose administered during the first five days of treatment did not show more beneficial effects than isolated administration of doxycycline.

Resumo: Os saguis-de-tufos-brancos (Callithrix jacchus) são pequenos primatas que pertencem à família Cebidae, subfamília Callitrichinae e são os mais conhecidos e comuns na adaptação ao cativeiro. A escassez de dados disponíveis na literatura sobre a anatomia desses saguis e de animais silvestres dificulta a aplicação de procedimentos anestésicos, cirúrgicos e terapêuticos apropriados. Visando conhecer as variações anatômicas da lobação e segmentação broncopulmonar foram dissecados os pulmões de nove cadáveres de saguis-de-tufos-brancos (Callithrix jacchus) adultos, sendo cinco machos e quatro fêmeas. Nos saguis, o pulmão direito apresentou lobo cranial; lobo médio; lobo caudal e lobo acessório; e o pulmão esquerdo os lobos cranial e caudal. As fissuras são bem proeminentes em ambos os pulmões. O brônquio principal direito emitiu ramos independentes, um para cada lobo, sendo que no lobo caudal seguiu em linha reta como a continuação deste brônquio e o mesmo foi observado no brônquio principal esquerdo. Em relação à segmentação broncopulmonar, o pulmão direito apresentou no lobo cranial variando de um a cinco ramos; lobo médio com um único ramo; o lobo caudal com três a cinco ramos e o acessório com três ramos. No pulmão esquerdo o lobo cranial teve uma variação de um a cinco e no caudal foi de três a quatro ramos.

Abstract The common marmoset (Callithrix jacchus) are small primates belonging to the family Cebidae, subfamily Callitrichinae and are the most well-known and common in adaptation to captivity. The scarcity of data in the literature on the anatomy of these marmosets and wild animals hinders the application of appropriate anesthetic and surgical procedures and therapeutics. In order to understand the anatomic variations in the lobation and bronchopulmonary segmentation the lungs were dissected from nine adult common marmoset (Callithrix jacchus) corpses, five males and four females. In the marmosets, the right lung presented cranial lobe, middle lobe, caudal lobe and accessory lobe while the left lung presented cranial and caudal lobes. The fissures were very pro-eminent in both the lungs. The main right bronchus emitted independent branches, one for each lobe, and it followed in a straight line in the caudal lobe as a continuation of this bronchus and the same was observed in the main left bronchus. The bronchopulmonary segmentation in the right lung ranged from one to five branches in the cranial lobe; the middle lobe had a single branch; the caudal lobe had three to five branches and the accessory lobe had three branches. In the left lung the cranial lobe bronchopulmonary segmentation ranged from one to five branches while in the caudal lobe it was three to four branches.

Um caso de lisencefalia e hipoplasia cerebelar é descrito em um caprino com 30 dias de idade. No exame físico, apresentava decúbito esternal permanente, ataxia, ausência do reflexo de ameaça, tremores de intenção e nistagmo. Após 11 dias de internamento, o caprino foi eutanasiado e necropsiado. Na necropsia, o cérebro não apresentava giros nem sulcos e o cerebelo estava reduzido de tamanho. Histologicamente, em todo o córtex cerebral, a substância cinzenta estava mais espessa e a substância branca mais fina que o normal. Os neurônios estavam distribuídos de forma aleatória na substância cinzenta. No cerebelo, as camadas estavam desorganizadas, com localização heterotópica das células. Os achados macroscópicos e histológicos são característicos de lisencefalia e hipoplasia cerebelar. A presença de um só animal afetado sugere que a malformação não é de origem infecciosa e o fato da lisencefalia nunca ter sido descrita antes em caprinos sugere que não é uma doença hereditária.

A case of lissencephaly and cerebellar hypoplasia was observed in a 30-day-old goat. The goat presented with sternal recumbence, absence of a menace response, intention tremors, ataxia, and nystagmus. The goat was euthanized and necropsied after having been hospitalised for eleven days. At necropsy, the surface of the brain was found to be smooth, the cerebral sulci and gyri were absent, and the cerebellum was reduced in size. Histologically, the grey matter and white matter were thicker and thinner than normal in cortices, respectively. The neurons were randomly arranged in the grey matter. In the cerebellum, the layers were disorganised, and cells were heterotopics. The histologic and gross lesions observed in this animal are characteristic of lissencephaly associated with cerebellar hypoplasia. The presence of a single goat affected suggests that the malformation was not of infectious origin and because lissencephaly is a malformation not previously described in goats, it is unlikely this case was inherited.

Para determinar a teratogenicidade de Mimosa tenuiflora, 15 ovelhas, distribuídas em dois grupos, foram introduzidos em área invadida pela planta. O Grupo 1, com seis ovelhas prenhes, foi introduzido na área experimental 20 dias após o acasalamento. O Grupo 2, formado por nove ovelhas não prenhes e um carneiro, foi introduzido na área experimental no início do experimento. O experimento começou no mês de outubro de 2009, período de estiagem, quando M. tenuiflora estava sementando. Nesse período as plantas foram rebaixadas a 40 cm de altura e os galhos com folhas e sementes foram disponibilizados para os ovinos na mesma área onde M. tenuiflora foi rebaixada. M. tenuiflora começou a rebrotar ainda na estação seca antes do período de chuvas. No período de rebrota, as ovelhas ficavam livres para pastar M. tenuiflora e recebiam concentrado em quantidade equivalente a 1% do peso vivo. Após as primeiras chuvas, em meados de janeiro do ano seguinte, quando o estrato herbáceo apareceu, essas ovelhas foram confinadas em baias, onde M. tenuiflora foi fornecida até o fim do experimento. A cada 15 dias eram realizados exames ultrassonográficos para acompanhamento da gestação. No Grupo 1, três ovelhas abortaram, cada uma um feto sem malformações. Outra ovelha pariu dois cordeiros, um com hiperflexão na articulação inter-falangeana proximal no membro torácico direito e outro sem malformações. Outra ovelha pariu um cordeiro com hiperflexão dos dois membros pélvicos na região da articulação tarso-metatársica. No grupo formado pelas ovelhas que foram acasaladas na área experimental, uma ovelha abortou um feto sem malformações e cinco pariram cordeiros normais. Três das ovelhas desse grupo não emprenharam durante todo o período experimental, mostrando retornos repetidos ao cio, sugerindo perda embrionária. Trinta e duas ovelhas e um carneiro, que permaneceram numa área vizinha a área experimental e foram utilizados como controle, pariram cordeiros normais. Conclui-se que M. tenuiflora, além de causar malformações causa, também, mortalidade embrionária e abortos em ovelhas.

To determine the teratogenicity of Mimosa tenuiflora, 15 sheep, divided into two groups, were introduced into an area invaded by the plant. Group 1 consisted of six pregnant ewes that were introduced into the experimental area 20 days after mating. Group 2 consisted of nine non pregnant sheep and a ram introduced into the area at the start of the experiment. The experiment began in October 2009, during the dry season, when M. tenuiflora was seeding. During this period the M. tenuiflora plants were pruned to 40cm tall and the branches with leaves and seeds were provided to the experimental sheep in the same area. After prunning M. tenuiflora began to sprout even in the dry season, and the sheep were free to graze the plant. They also received concentrate ration in amount equivalent to 1% of their body weight. After the first rains in mid-January 2010, when the herbaceous layer appeared, the pregnant sheep were confined in stalls, and M. tenuiflora was cut in the field and given to the sheep until the end of the experiment. Every 15 days each sheep was examined by ultrasound to control pregnancy. In Group 1, three sheep aborted single fetuses without malformations. One sheep delivered two lambs, one with hyperflexion of the proximal inter-phalangeal joint of the right forelimb and another without malformations. Another sheep delivered a lamb with a hyperflexion of both hindlimbs in the region of the tarsal-metatarsal joint. Only one sheep delivered a normal lamb. In Group 2, one sheep aborted a fetus without malformations and five delivered normal lambs. Three sheep of this group returned to estrus repeatedly and did not get pregnant during the mating period, suggesting embryonic loss. Thirty two ewes and one ram, that stayed in a paddock neighbor to the experimental paddock and were used as control group, delivered normal lambs. It is concluded that M. tenuiflora cause malformations, embryonic mortality and abortion in sheep.

The objective of this study was to evaluate the effect of the levels of replacement of ground corn by forage cactus meal in the diet on the muscularity and adiposity of carcass of Santa Inês lambs finished at feedlot. This study was carried out at Estação Experimental de Pendência, belonging to Empresa de Pesquisa Agropecuária da Paraíba S.A. (EMEPA-PB). Forty male Santa Inês lambs in feedlot were used in the experiment. Treatments were randomly assigned to the animals according to a completely randomized design, with four treatments, that consisted of growing substitution levels of ground corn for forage cactus meal: 0, 33, 66 and 100% of substitution and ten replications (lambs). Animals were slaughtered and carcasses cooled for 24 hours for later assessment of conformation, morphometry, loin eye-muscle area, fatness, perirenal fat, marbling and subcutaneous fat thickness. Legs were separated for dissection of muscle, bone, subcutaneous fat, intermuscle fat and total fat, which were weighed for the determination of the muscle:bone and muscle:fat relation and the relative weight of tissue components. Averages were submitted to variance and regression analyses at a 5% level of probability. Diets had no effect on carcass conformation. However, a negative linear effect on weights and yields of fats was observed with the increased levels of forage cactus meal in the diet, and the opposite was observed in the muscle yield behavior. Forage cactus meal is biologically as efficient as ground corn, because it increases the muscularity and reduces the adiposity of the carcass of Santa Inês lambs in feedlot.

The objective of this study was to evaluate the effect of the replacement of a ground corn diet by a forage cactus meal diet on the carcass characteristics and body components of Santa Inês lambs finished in feedlot. This study was carried out at Estação Experimental de Pendência, belonging to Empresa de Pesquisa Agropecuária da Paraíba S.A. (EMEPA-PB). Forty Santa Inês male lambs in feedlot were used in the experiment. Treatments were randomly assigned to the animals according to a completely randomized design, with four treatments, which consisted of growing replacement levels of ground corn by forage cactus meal: 0, 33, 66 and 100% of substitution and ten replications (lambs). Animals were slaughtered, and the following characteristics were evaluated: body weight, empty body weight, hot carcass weight, cold carcass weight, non-carcass components (NCC), hot carcass yield, cold carcass yield, biological yield, revenue of non components of carcass, revenues of non-carcass components, relative weight and relative value of the commercial cuts, viscera and organs' yield. Averages were submitted to analysis of variance and regression analyses at a 5% level of probability. The replacement levels of ground corn by forage cactus meal had no influence on biological yield, revenue of the non components of carcass, relative weight and relative value of the prime and choice cuts or on the relative weight of viscera and organs. The replacement of ground corn by forage cactus meal, on the ration given to Santa Ines lambs in feedlot does not impact the biological yield, relative weight and relative value of prime and choice cuts or the relative weight of viscera and other organs.

Objetivou-se com este trabalho avaliar o efeito da suplementação na composição tecidual e química da perna e do lombo de ovinos Santa Inês terminados em pastejo. Foram utilizados 24 ovinos castrados, com peso vivo médio (PV) de 15,8 kg e 3 a 4 meses de idade, distribuídos em três níveis de suplementação com concentrado (0; 1,0 e 1,5% do PV), num delineamento experimental inteiramente casualizado, com três tratamentos e oito repetições. A perna e o lombo foram dissecados em músculo, ossos e gordura, para determinação da composição tecidual, e a carne foi utilizada na determinação da composição química. A suplementação influenciou os rendimentos de músculos, ossos, gordura, matéria seca, cinzas, proteína bruta e gordura do lombo e da perna. A suplementação melhora o rendimento muscular e a composição química do lombo e da perna de ovinos Santa Inês terminados em pastagem nativa. Quando o objetivo for obter carcaças mais leves, o nível de concentrado recomendável é de 1,0% do PV e, se a finalidade for adquirir carcaças mais pesadas, recomenda-se o nível de 1,5%.

The objective of this study was to evaluate the effects of feed supplementation on the chemical and tissue composition of leg and loin from carcass of Santa Inês lambs, finished on pasture. Twenty-four castrated 3 to 4 month-old Santa Inês lambs were used, initial live body weight (LW) 15.8 kg, distributed in three concentrate supplementation levels (0.0, 1.0 and 1.5% LW). A randomized complete design was used, with three treatments and eight replications (lambs). The leg and loin were dissected in muscle, bone, fat and to determine tissue composition and the meat was submitted to chemical analyses. The supplementation influenced the yields of loin and leg muscles, bones, fat, dry matter, ash, crude protein and fat. The supplementation improved muscle yield and chemical composition of the loin and leg from Santa Inês lambs finished on native pasture. When the objective is to produce lighter carcasses, the recommended concentrate level is 1.0% LW, and 1.5% LW is recommended to produce heavier carcasses.

Objetivou-se, com este trabalho, avaliar a degradabilidade "in situ" do rolão de milho e do farelo de milho em caprinos e ovinos deslanados, mantidos em ambientes de sombra natural e artificial, no Semiárido paraibano. Foram utilizados quatro caprinos e quatro ovinos distribuídos em dois ambientes, um natural e outro artificial. Foram incubados sacos de náilon, contendo amostras do rolão e farelo de milho nos tempos de 6, 12, 24 e 48 e 72 horas para o alimento volumoso e 6, 12, 24, 48 horas para o concentrado. Os efeitos dos ambientes e das espécies na fração b e c da MS no rolão de milho foram independentes. No ambiente artificial, a média da degradabilidade da fração b (55,36%) foi superior à média obtida no ambiente natural (50,97%) e a fração c apresentou maior valor no ambiente natural (40,90%) do que o artificial (36,51%). Quanto à fração b e c da MS do farelo de milho, não houve interação entre espécies e ambientes, a degradabilidade da fração b da MS para a espécie caprina foi superior à ovina com 60,77% e 56,47%, respectivamente. Ocorrendo o inverso para a fração c, onde os ovinos apresentaram média superior aos caprinos (31,93 e 27,63%). Houve efeito da ambiente para a DP da MS do rolão de milho, os valores da fração b no ambiente natural e artificial foram (50,97 e 55,36%) respectivamente. A DP da MS do farelo de milho para a espécie caprina foi maior do que para a espécie ovina (72,37 e 68,07%, respectivamente). A degradabilidade efetiva a 5% da MS foi maior para caprinos (31,17%) do que para ovinos (28,48%). A DE da MS (calculada com taxa de passagem de 2 e 5%/ h) do farelo de milho para a espécie caprina foi superior (60,34 e 49,18%) a da ovina (56,88 e 46,51%, respectivamente). Concluiu-se que tanto a espécie como o ambiente influenciam na degradabilidade dos alimentos. Os ovinos e caprinos apresentaram características semelhantes em relação a degradabilidade da matéria seca, proteína bruta e fibra em detergente neutro do rolão de milho. Todavia, para o farelo de milho, os ovinos demonstram-se mais eficientes na degradabilidade da proteína bruta.

The objective of this study was to evaluate "in situ" degradability of ground cob corn and corn (maize) bran in goats and wooless sheep kept in natural and artificial shade environments in the semi-arid region of Paraíba. Four goats and four sheep were used, being distributed in two environments, one natural and the other artificial. Nylon sacks were incubated containing samples of ground cob corn and corn (maize) bran in intervals of 6, 12, 24, 48, and 72 hours for the bulk food, and 6, 12, 24, and 48 hours for the concentrate. The effects of the environments and of the species in fractions b and c of dry matter in the cob corn were independent. In the artificial environment, the average of the degradability of fraction b (55,36%) was higher than the average obtained in the natural environment (50,97%); and fraction c presented a higher value in the natural environment (40,90%) than in the artificial (36,51). With respect to fractions b and c of the dry matter of the corn bran, there was no interaction between species and environments; and the degradability of fraction b of dry matter for the goats was higher than for the sheep, with 60,77% and 56,47%, respectively. With respect to fraction c, the inverse was verified. The sheep presented a higher average than the goats (31,93 and 27,63%). There was environmental effect for potential degradability of dry matter of the cob corn. The values of fraction b in the natural and artificial environments were 50,97 and 55,36%, respectively. The potential degradability of corn bran for the goats was higher than for the sheep (72,37 and 68,07%, respectively). The effective degradability to 5% of the dry matter was higher for the goats (31,17%) than for the sheep (28,48%). The effective degradability of the dry matter (calculated with passage rate of 2 and 5%/h) of the corn bran for the goats was superior (60,34 and 49,18%) as compared to the sheep (56,88 and 46,51%, respectively). It can be concluded that animal species and environment have an influence on food degradability. The sheep and goats in this study presented similar characteristics with respect to the degradability of dry matter, crude protein, and neutral detergent fiber of the cob corn. However, with respect to the corn bran, the sheep were more efficient in degradability of crude protein, as the goats were in degradability of dry matter.

Realizou-se este estudo com dezesseis caprinos machos, sendo oito exóticos (4 da raça Boer e 4 da Anglo-Nubiana) e oito naturalizados (4 da raça Moxotó e 4 da Pardo-Sertaneja), todos puros e com idade de um ano. Os animais tiveram a temperatura retal, freqüência respiratória, freqüência cardíaca, temperatura da fronte, das costelas, do flanco e do escroto, mensuradas pela manhã e à tarde, no período de 21 de agosto a 04 de Setembro de 2002, e foram submetidos a um teste de tolerância ao calor no período de 5 a 17 do mês de setembro de 2002, sob às condições do clima semi-árido do Nordeste do Brasil. Observou-se efeito do turno e da raça sobre os parâmetros fisiológicos estudados. As temperaturas e freqüências foram na grande maioria superiores (p < 0,05) no turno da tarde. Quanto à tolerância ao calor não houve diferença significativa (p < 0,05) entre as raças, apesar da raça Boer ter apresentado o maior índice de tolerância ao calor. Os animais da raça Boer apresentaram Muito Alta Tolerância ao calor e os das demais raças, Alta Tolerância. As raças Boer e Anglo-Nubiana, apesar de exóticas, apresentaram temperaturas, freqüências e índice de tolerância ao calor que às referendam como adaptadas ao clima semi-árido do nordeste brasileiro.

Sixteen goats males, eigth exotic (4 from the breed Boer and 4 from the Anglo-Nubiana) and eigth naturalized (4 from the race Moxotó and 4 from the Brown-Pardo-Sertaneja), all pure and one year old. The temperature rectal, respiratory frequency, cardiac frequency, temperature from the forehead, of the ribs, of the flank and of the scrotum, was taken in the morning and afternoon during the period from 21 august to 4 september of 2002. A you had of. The animals were submitted to the tolerance to the heat in the period from 5 to 17 of september of 2002 on the demi-dry climate of the northeast of Brazil. The data shown effect of breed on the physiological parameters studied. The temperatures and frequencies were higher (P <0.05) in the afternoon period. The tolerance to the heat had not significant difference (P <0.05) among the breeds, therefore breed Boer shown the highest index of tolerance to the heat. The animals from the breed Boer ahown a higher tolerance to the heat in relation to the others breed that shown higl tolerance. The breeds Boer and Anglo-Nubiana, despite of exotic, shown temperatures, frequencys and index of tolerance to the heat that should be considered as adapted to the demi-dry climate of the Brazilian northeast.