Abstract Introduction Circulatory system diseases are one of the leading causes of death. Periodontal health is a component of oral and general health that contributes to quality of life. Objective To analyze periodontal conditions and quality of life in patients with circulatory diseases. Material and method Cross-sectional study, with patients with circulatory diseases (n=125). The clinical periodontal examination was performed considering: biofilm, bleeding on probing, suppuration, probing depth, gingival recession, and clinical attachment level. Quality of life was assessed with the Medical Outcomes Study 36 – Item Short-Form Health Survey (SF-36) and Oral Health Impact Profile – short form (OHIP-14). Data were analyzed with parametric and nonparametric tests (α=5%). Result Elderly and men had a greater severity of periodontal disease. The Elderly had lower values in the domains of "Functional capacity" and "Physical aspects" (SF-36). The domain "Pain" had lower values in subjects with health/gingivitis. OHIP-14 did not show differences in the comparisons. There was no correlation between quality of life and the severity of periodontal disease. Conclusion Among patients with circulatory diseases, the elderly and men had greater severity of periodontal disease. The elderly had a poorer quality of life (functional capacity and physical aspects). There was no correlation between the severity of periodontal disease and quality of life.

Resumo Introdução As doenças do aparelho circulatório representam uma das principais causas de mortes. A saúde periodontal é um componente da saúde bucal e saúde geral que contribui para a qualidade de vida. Objetivo Analisar as condições periodontais e a qualidade de vida em pacientes com doenças circulatórias. Material e método Estudo transversal, com pacientes com doenças circulatórias (n=125). O exame clínico periodontal foi realizado considerando: biofilme, sangramento à sondagem, supuração, profundidade de sondagem, recessão gengival e nível de inserção clínica. A qualidade de vida foi avaliada com o Medical Outcomes Study 36 – Item Short-Form Health Survey (SF-36) e Oral Health Impact Profile – short form (OHIP-14). Os dados foram analisados com testes paramétricos e não paramétricos (α=5%). Resultado Idosos e os homens tiveram maior severidade da doença periodontal. Idosos apresentaram menores valores nos domínios “Capacidade funcional” e “Aspectos físicos” (SF-36). O domínio “Dor” teve menor valor nos indivíduos com saúde/gengivite. OHIP-14 não apresentou diferenças nas comparações. Não houve correlação entre qualidade de vida a severidade da doença periodontal. Conclusão Entre os pacientes com doenças circulatórias, os idosos e os homens tiveram maior severidade da doença periodontal. Idosos tiveram pior qualidade de vida (capacidade funcional e aspectos físicos). Não houve correlação entre a severidade da doença periodontal e a qualidade de vida.

RESUMO A síndrome de Down (SD) é uma das principais causas de deficiência intelectual. Os objetivos deste estudo foram comparar parâmetros bioquímicos e hematológicos, bem como encontrar a relação triglicerídeo/colesterol da lipoproteína de alta densidade (HDL-C) e a razão neutrófilo/linfócito em indivíduos com deficiência intelectual (DI) associada ou não à SD. O principal resultado foi a diminuição do HDL-C em indivíduos com SD quando comparados àqueles com DI, sugerindo que essa modificação no perfil lipídico pode se relacionar com alterações genéticas. Portanto, pesquisas adicionais são importantes para analisar se existe ligação entre a trissomia 21 e a redução dos níveis de HDL-C em indivíduos com SD.

ABSTRACT Down syndrome (DS) is one of the most leading causes of intellectual disability. The aim of this study was to compare biochemical and hematological parameters, triglyceride/high-density lipoprotein cholesterol (HDL-C) and neutrophil/lymphocyte ratios in individuals with intellectual disabilities (ID) associated or not with DS. The main result is the lower HDL-C level in individuals with DS than in the ID group, suggesting a modification in the lipid profile whose origin would lie in genetic alterations. However, further researches are important to analyze if there is any link between trisomy 21 and the reduction of plasma HDL-C levels in individuals with DS.

Abstract Periodontal research involves the use of animal models to better understand the biological processes of periodontal diseases and the potential of new or existing therapies. Currently, ligature-induced periodontitis in rats is the main model used in periodontal research, in this model, alveolar bone loss (ABL) is the main parameter evaluated by radiographic, morphometric, and histological techniques. Interestingly, although these methodologies are widely used, it is not totally clarified neither the kinetics of ABL over the induction time nor the agreement degree (repeatability and reproducibility) of these techniques. Objective: To characterize ABL kinetics at 0, 3, 7, 15, 30, and 60 days after ABL induction by ligature and to evaluate the intra- (repeatability) and inter-examiner (reproducibility) agreement and the correlation among the radiographic, morphometric, and histological methodologies. Material and Methods: 60 male Wistar rats with induced ABL were randomly divided into 6 experimental groups (n = 10 animals/group). After 0, 3, 7, 15, 30, and 60 days, the animals were euthanized and their hemimandibles were removed for ABL determination using radiographic, morphometric and histological techniques. Results: Radiographic and morphometric/linear techniques allowed the detection of statistically significant ABL on the third day, while histological and morphometric/area techniques could only detect ABL after the seventh day (ANOVA/Tukey, p<0.05). After the fifteenth day, except for histological analysis, the ABL was stabilized. Concerning the agreement of the methodologies, Bland Altman's test (intra and inter-examiner evaluations) showed no difference among the measurements (p>0.05). In addition, high correlations (Pearson's test, r2>0.9, p<0.05) were observed. Conclusion: The results indicated that the minimum time for ABL induction could vary from 3 to 7 days, according to the chosen analysis methodology. Agreement and correlation data support the comparison of results between studies with same induction time.

Avaliou-se a microdureza de uma resina composta para dentes clareados fotoativada com diferentes fontes de luz fotoativadora. Espécimes de resina composta (3M ESPE Filtek Supreme) foram aplicados a cilindros de latão (2 mm de espessura, 5 mm de diâmetro). Três fontes comerciais de luz LED foram utilizadas para polimerizar os espécimes e os resultados foram comparados aos obtidos utilizando-se uma fonte de luz halógena convencional. As fontes de luz utilizadas no presente estudo foram: Demetron Optilux 401 (QTH), 3M ESPE Elipar FreeLight (LED 1); Kerr L.E.Demetron I (LED 2), e ColtoluxLED lights (LED 3). A microdureza das superfícies topo e base foram avaliadas com um microdurômetro digital (Dureza Vickers), sob aplicação de carga. Na superfície base não se observou diferença significante entre as fontes de luz utilizadas (ANOVA, dois critérios). Na superfície topo, a fonte de luz QTH apresentou valores de dureza significantemente maiores quando comparado aos valores apresentados quando LED 1 e LED 3 foram utilizadas. Não houve diferença significante entre QTH e LED 2. Observou-se também diferença significante entre os valores das superfície topo, que foram significantemente superiores, e base. A densidade de potência das fontes de luz fotoativadoras mostrou ser responsável pela dureza da resina composta e não a irradiância.

The microhardness of a bleaching-shade resin composite polymerized with different light-curing units was evaluated. Composite samples (3M ESPE Filtek Supreme) were applied to brass rings (2 mm in thickness, 5 mm in diameter). Three commercial LED lights were used to polymerize the specimens and the results were compared to those of a conventional halogen light. The light sources used in the present study were: Demetron Optilux 401 (QTH), 3M ESPE Elipar FreeLight (LED 1); Kerr L.E.Demetron I (LED 2), and ColtoluxLED lights (LED 3). The microhardness of the top and bottom surfaces was assessed with a digital Vickers hardness-measuring instrument, under load. At the bottom surface, no significant difference among the light sources was observed (two-way ANOVA). At the top surface, the QTH light source presented significantly higher hardness values compared to the values observed when LED 1 and LED 3 were used. There were no significant differences between the QTH and LED 2 light sources. Significantly higher hardness values were also found at the top surface when compared to the values observed at the bottom surface. The power density of the polymerization light sources seemed to be responsible for the observed resin composite hardness, not their irradiance.