ABSTRACT Muscle weakness has been associated to insulin resistance and metabolic syndrome in the general population. However, it is still unclear whether this association is maintained in older adults. This study investigated correlations between low handgrip strength (HGS) and metabolic syndrome, or some of its components, in older adults through a systematic review of the literature. Searches were conducted in the Virtual Health Library Regional Portal, Scopus, Cochrane, Embase, MEDLINE/PubMed, SciELO, and Web of Science databases for relevant studies investigating muscle weakness (measured by hand dynamometer) and metabolic syndrome or its components in older adult populations, published up to September 2023. From the 2050 references initially identified, 20 studies, comprising a total of 31,264 older adults of both genders, completely met the inclusion/exclusion criteria. Eighteen studies showed that lower HGS was associated with metabolic syndrome or some of its risk factors, such as abdominal obesity, hyperglycemia, insulin resistance, dyslipidemia, or high blood pressure. Two studies found that older men with high blood pressure had increased HGS. Most studies included in this systematic review revealed a significant correlation between reduced HGS and metabolic syndrome or some of its components, especially abdominal obesity and insulin resistance. We conclude that below-average HGS can be associated with metabolic syndrome in older adults. population However (HGS literature Portal Scopus Cochrane Embase MEDLINEPubMed MEDLINE PubMed MEDLINE/PubMed SciELO measured dynamometer populations 2023 205 identified 2 31264 31 264 31,26 genders inclusionexclusion inclusion exclusion criteria factors hyperglycemia dyslipidemia belowaverage below average 202 3126 3 26 31,2 312 31,

Introduction: The role of the fatty acid in the prevention or progression of chronic diseases has generated significant interest on the part of researchers. Thus, our objective was to evaluate the long-term effects of high-fat diet containing soybean or canola oil on body development and bone parameters of male rats. Methods: After weaning, rats were grouped and fed either a control diet (7S) or a high-fat diet containing soybean (19S) or canola oil (19C). Femur and lumbar vertebra (LV4) structure were determined at 180 days by dual-energy X-ray absorptiometry and computed tomography. Results: The groups showed similar food intake, body mass and length development. The bone parameters of the 19C were similar to the control group, while the 19S showed lower bone parameters when compared to the other groups. Conclusions: The high-fat diet containing soybean oil was unfavorable to bone structure, while the canola oil contributed bone health during the adult stage of life.

Introducción: El papel del ácido graso en la prevención o la progresión de las enfermedades crónicas ha generado un interés significativo por parte de los investigadores. Por lo tanto, nuestro objetivo fue evaluar los efectos a largo plazo de la dieta alta en grasas que contienen soja o aceite de canola en los parámetros de desarrollo del cuerpo y los huesos de ratas macho. Métodos: Después del destete, las ratas se agruparon y se alimentaron con una dieta control (7S) o una dieta alta en grasa que contiene soja (19S) o aceite de canola (19C). Fémur y vértebras lumbares (LV4) estructura se determinaron a los 180 días por absorciometría dual de rayos X y tomografía computarizada. Resultados: Los grupos mostraron similares ingesta de alimentos, la masa corporal y el desarrollo de longitud. Los parámetros óseos de la 19C fueron similares al grupo control, mientras que los 19S mostró parámetros óseos inferiores en comparación con los otros grupos. Conclusiones: La dieta alta en grasas que contiene aceite de soja fue desfavorable a la estructura ósea, mientras que el aceite de canola contribuyó salud de los huesos en la etapa adulta de la vida.