ABSTRACT Objective: To measure the costs of preventive and therapeutic protocols of Photobiomodulation (PBM) for oral mucositis (OM) and their budgetary impact on Brazil’s Ministry of Health (BMH). Material and Methods: A partial economic analysis was performed to estimate the costs using a bottom-up approach from a social perspective. Monetary values were assigned in Brazilian reais (BRL). The costs of the preventive protocol were calculated for five, 30, and 33 consecutive PBM sessions, depending on the antineoplastic treatment instituted. The costs of the therapeutic protocol were calculated for 5 or 10 sessions. The annual financial and budgetary impact was calculated considering the groups of oncologic patients with a higher risk of development of OM, such as those with head and neck and hematological cancer and pediatric patients. Results: The cost of a PBM session was estimated at BRL 23.75. The financial impact of providing one preventive protocol per year for all oncologic patients would be BRL 14,282,680.00, 0.030% of the estimated budget for hospital and outpatient care of the BMH in 2022. The financial and budgetary impacts of providing one treatment for OM for all patients in one year would be BRL 2,225,630.31 (0.005%, most optimistic scenario) and BRL 4,451,355.63 (0.009%, most pessimistic scenario). Conclusion: The budgetary impact of implementing PBM protocols in the Brazilian Healthcare System is small, even in a pessimistic scenario. Objective (PBM (OM Brazils Brazil s BMH. . (BMH) Methods bottomup bottom up perspective BRL. (BRL) five 30 3 sessions instituted 1 Results 2375 23 75 23.75 1428268000 14 282 680 00 14,282,680.00 0030 0 030 0.030 2022 222563031 2 225 630 31 2,225,630.3 0.005%, 0005 005 (0.005% scenario 445135563 4 451 355 63 4,451,355.6 0.009%, 0009 009 (0.009% Conclusion small (BMH (BRL 237 7 23.7 142826800 28 68 14,282,680.0 003 03 0.03 202 22256303 22 2,225,630. 0.005% 000 (0.005 44513556 45 35 6 4,451,355. 0.009% (0.009 23. 14282680 14,282,680. 0.0 20 2225630 2,225,630 0.005 (0.00 4451355 4,451,355 0.009 1428268 14,282,680 0. 222563 2,225,63 0.00 (0.0 445135 4,451,35 142826 14,282,68 22256 2,225,6 (0. 44513 4,451,3 14282 14,282,6 2225 2,225, (0 4451 4,451, 1428 14,282, 222 2,225 ( 445 4,451 142 14,282 2,22 44 4,45 14,28 2,2 4,4 14,2 2, 4, 14,

Abstract Objective: To describe the impact of the COVID-19 pandemic on dental care provided to pediatric cancer patients assisted in a referral hospital. Material and Methods: This is an observational, retrospective study based on secondary data extracted from worksheets of dental procedures for patients aged between 0 and 19 years assisted in the pediatric oncology sector of a hospital in João Pessoa, PB, Brazil. Dental procedures performed by the interdisciplinary team of researchers from August 2018 to February 2020 (19 months prior to the pandemic) and from April 2020 to October 2021 (19 months during the pandemic) were totaled and compared. A descriptive analysis of the data was performed. Results: There was a reduction of 80.2% in dental interventions implemented in the sector during the pandemic, with the number of procedures decreasing from 6,210 (the period before the pandemic) to 1,229 (during the pandemic). Most procedures in both periods were performed for patients assisted in beds, for whom there was a reduction of care provided for 81.2% from 5,275 to 994 procedures. Dental procedures in the outpatient clinic decreased by 74.9%, from 935 to 235. Conclusion: The COVID-19 pandemic negatively impacted dental care provided to pediatric oncology patients by restricting dental procedures to emergency demands, compromising performance prevention and health promotion actions.

ABSTRACT Objective: To evaluate the antibacterial effect and the solubility of experimental root canal filling pastes containing the phytoconstituents terpineol and cinnamaldehyde. Material and Methods: Minimum Inhibitory Concentration (MIC) of each phytoconstituent was determined against Enterococcus faecalis. Five groups of antibiotic pastes based on zinc oxide were obtained by mixing: only terpineol, only cinnamaldehyde, terpineol and cinnamaldehyde combined, chlorhexidine (antibiotic control), and CTZ paste (control paste). Antibacterial activity was analyzed through direct contact test within 24 and 72 hours. Solubility was evaluated by spectrophotometry within 48 and 144 hours. Antibacterial activity data were analyzed descriptively, and solubility data was analyzed using ANOVA and Tukey tests (p<0.05). Results: The MIC obtained for terpineol and cinnamaldehyde were, respectively, 2000 µg/mL and 500 µg/mL. After 24h, only the terpineol paste did not inhibit E. faecalis growth. After 72h, all groups inhibited E. faecalis growth. After 48h, the highest solubility was verified in the terpineol paste (p<0.05), and no differences were detected among other groups (p>0.05). After and 144h, highest solubility was observed in the terpineol paste (p<0.05), followed by the CTZ paste (p<0.05). No differences were detected for cinnamaldehyde, terpineol+cinnamaldehyde and chlorhexidine pastes (p>0.05). Conclusion: Pastes containing cinnamaldehyde or terpineol+cinnamaldehyde showed antibacterial activity against E. faecalis similar to CTZ paste, with lower solubility.

Abstract This study aimed to analyze the influence of socioeconomic factors on the frequency of diagnoses of oral mucosal changes and the number of hospitalized patients with oral and oropharyngeal cancer in Brazil. This cross-sectional study analyzed data from all Brazilian cities in the period 2011–2017. The frequency of diagnoses of oral mucosal changes and the number of hospitalized patients of oral and oropharyngeal cancer in Brazil were extracted from the Primary Care Information System (SIAB) and Brazilian National Cancer Institute (INCA) databases. The socioeconomic factors evaluated were the Gini coefficient of inequality, municipal Human Development Index (MHDI), inadequate basic sanitation rate, employment rate, illiteracy rate and expected years of schooling. Associated factors were examined using bivariate Spearman’s correlations and multivariate Poisson regressions, and statistically significant (p < 0.05) correlations between study variables and regression coefficients were obtained. A higher frequency of diagnoses of mucosal changes was observed in cities with a higher Gini coefficient (B = 11.614; p < 0.001), higher MHDI (B = 11.298; p < 0.001), and higher number of hospitalized patients with oral and oropharyngeal cancer (B = 0.001, p < 0.002). Cities with higher Gini coefficients (B = 8.159, p < 0.001), higher inadequate basic sanitation rates (B = 0.09, p = 0.001), lower expected years of schooling (B = -0.718, p < 0.001), and higher illiteracy rates (B = 0.191, p < 0.001) had a higher frequency of hospitalized patients with oral and oropharyngeal cancer. In conclusion, more developed cities showed a higher frequency of diagnoses of mucosal changes. Greater inequality and worse socioeconomic conditions are associated with a higher frequency of hospitalized patients with oral and oropharyngeal cancer in Brazil.

Resumo Esta revisão sistemática comparou o estado de saúde bucal entre idosos institucionalizados e não institucionalizados. As seguintes bases de dados eletrônicas foram pesquisadas: PubMed (Medline), Scopus, Web of Science, Lilacs e Cochrane Library, de forma abrangente e irrestrita. Pesquisas eletrônicas recuperaram 1.687 artigos, que foram analisados com relação aos respectivos critérios de elegibilidade. Após a leitura de títulos e resumos, cinco estudos foram incluídos e analisados quanto à qualidade metodológica. A condição bucal de idosos institucionalizados e não institucionalizados foi comparada por meio de meta-análise. Os artigos incluídos envolveram um delineamento transversal, que investigou 1.936 indivíduos acima de 60 anos, sendo 999 institucionalizados e 937 não institucionalizados. Investigou-se a prevalência de edentulismo, a experiência de cárie e a condição periodontal. A meta-análise revelou que idosos institucionalizados possuem maior prevalência de edentulismo (OR = 2,28, IC95% = 1,68-3,07), maior número de dentes cariados (DM = 0,88, IC95% = 0,71-1,05) e de dentes perdidos (DM = 4.58, IC95% = 1,89-7,27). A condição periodontal ruim não diferiu significativamente entre os grupos. Comparados aos não institucionalizados, os idosos institucionalizados tem pior experiência de cárie.

Abstract This systematic review compared the oral health status between institutionalized and non-institutionalized elders. The following electronic databases were searched: PubMed (Medline), Scopus, Web of Science, Lilacs and Cochrane Library, in a comprehensive and unrestricted manner. Electronic searches retrieved 1687 articles, which were analyzed with regards to respective eligibility criteria. After reading titles and abstracts, five studies were included and analyzed with respect their methodological quality. Oral status of institutionalized and non-institutionalized elderly was compared through meta-analysis. Included articles involved a cross-sectional design, which investigated 1936 individuals aged 60 years and over, being 999 Institutionalized and 937 non-institutionalized elders. Studies have investigated the prevalence of edentulous individuals, the dental caries experience and the periodontal status. Meta-analysis revealed that institutionalized elderly have greater prevalence of edentulous (OR = 2.28, 95%CI = 1.68-3.07) and higher number of decayed teeth (MD = 0.88, 95%CI = 0.71-1.05) and missed teeth (MD = 4.58, 95%CI = 1.89-7.27). Poor periodontal status did not differ significantly between groups. Compared to non-institutionalized, institutionalized elders have worse dental caries experience.

Resumo Esta revisão sistemática comparou o estado de saúde bucal entre idosos institucionalizados e não institucionalizados. As seguintes bases de dados eletrônicas foram pesquisadas: PubMed (Medline), Scopus, Web of Science, Lilacs e Cochrane Library, de forma abrangente e irrestrita. Pesquisas eletrônicas recuperaram 1.687 artigos, que foram analisados com relação aos respectivos critérios de elegibilidade. Após a leitura de títulos e resumos, cinco estudos foram incluídos e analisados quanto à qualidade metodológica. A condição bucal de idosos institucionalizados e não institucionalizados foi comparada por meio de meta-análise. Os artigos incluídos envolveram um delineamento transversal, que investigou 1.936 indivíduos acima de 60 anos, sendo 999 institucionalizados e 937 não institucionalizados. Investigou-se a prevalência de edentulismo, a experiência de cárie e a condição periodontal. A meta-análise revelou que idosos institucionalizados possuem maior prevalência de edentulismo (OR = 2,28, IC95% = 1,68-3,07), maior número de dentes cariados (DM = 0,88, IC95% = 0,71-1,05) e de dentes perdidos (DM = 4.58, IC95% = 1,89-7,27). A condição periodontal ruim não diferiu significativamente entre os grupos. Comparados aos não institucionalizados, os idosos institucionalizados tem pior experiência de cárie.

Abstract This systematic review compared the oral health status between institutionalized and non-institutionalized elders. The following electronic databases were searched: PubMed (Medline), Scopus, Web of Science, Lilacs and Cochrane Library, in a comprehensive and unrestricted manner. Electronic searches retrieved 1687 articles, which were analyzed with regards to respective eligibility criteria. After reading titles and abstracts, five studies were included and analyzed with respect their methodological quality. Oral status of institutionalized and non-institutionalized elderly was compared through meta-analysis. Included articles involved a cross-sectional design, which investigated 1936 individuals aged 60 years and over, being 999 Institutionalized and 937 non-institutionalized elders. Studies have investigated the prevalence of edentulous individuals, the dental caries experience and the periodontal status. Meta-analysis revealed that institutionalized elderly have greater prevalence of edentulous (OR = 2.28, 95%CI = 1.68-3.07) and higher number of decayed teeth (MD = 0.88, 95%CI = 0.71-1.05) and missed teeth (MD = 4.58, 95%CI = 1.89-7.27). Poor periodontal status did not differ significantly between groups. Compared to non-institutionalized, institutionalized elders have worse dental caries experience.

Abstract Objective: To determine the occurrence and severity of oral mucositis (OM) and the factors associated with the onset of severe oral mucositis (SOM) in pediatric cancer patients. Material and Methods: This was a longitudinal and prospective study with 85 children and adolescents (aged 0 to 19 years) admitted to the Pediatric Oncology Sector of Napoleão Laureano Hospital between November 2016 and July 2019. The patients’ sociodemographic and epidemiological information, as well as hematological and biochemical parameters, were obtained from their medical charts. The oral mucosa of study participants was assessed through the modified Oral Assessment Guide (OAG) at baseline and after the 2nd, 5th and 10th week of antineoplastic treatment. Data were analyzed by Chi-square test to determine the factors associated with the occurrence of SOM (p<0.05). Results: The occurrence of OM was more frequent in the 2nd (60%), 5th (40.9%) and 10th week (43.2%) of antineoplastic treatment. During the follow-up period, SOM was more frequent in the 5th week (34.7%), followed by the 2nd (32.3%) and 10th weeks (29.7%). There was no association between the occurrence of SOM and the patient's age, type of tumor, chemotherapy regimen, and hematological and biochemical parameters. Conclusion: The occurrence of oral mucositis in pediatric cancer patients was significant, especially in the 2nd week of antineoplastic treatment. Severe oral mucositis was more prevalent in the 5th week of treatment and was not associated with any of the study variables.

Abstract Objective: To evaluate self-medication for toothache and its associated factors in children and adolescents. Material and Methods: A cross-sectional study was carried out with 252 children/adolescents aged 6-16 years. A questionnaire was applied with questions related to demographic and socioeconomic characteristics; experience of, and self-medication for, toothache; as well as aspects related to the condition. Descriptive and inferential statistical analyses (Pearson's Chi-square test and Fisher's exact test) were performed, with a 5% significance level. Results: The prevalence of toothache was 41.7%. In 96 cases analyzed, there was prevalence of 69.8% of self-medication for toothache. There were no statistically significant associations between self-medication for toothache and variables related to the children/adolescents (gender and age), their parents or guardians (age and schooling), socioeconomic characteristics (family income and number of people in the household) and aspects related to toothache (fever, crying and school absenteeism) (p>0.05). The most commonly used drug was paracetamol (60.7%), whose choice was based to its previous use by the study population for conditions not related to toothache (47.8%). Conclusion: There was a high prevalence of self-medication for toothache in the study population. No independent variable was associated with self-medication practice.

Abstract Objective: To verify differences between salivary flow in pediatric cancer patients before starting antineoplastic treatment and in healthy pediatric patients. Material and Methods: This is an observational, cross-sectional, paired study with sample of 120 children and adolescents (3-18 years). Thirty pediatric cancer patients were selected for convenience at “Napoleão Laureano” Hospital (G1). Another group was composed of 90 individuals attended at the School of Dentistry Clinics of the Federal University of Paraíba, matched by age (G2). Data collection was performed in two steps for both groups. Information regarding pediatric cancer patients was obtained by interview with parents / guardians and searching medical records, while in the other group by interview with parents / guardians. Saliva collection was performed using standard method in both groups: unstimulated salivary flow rate (USFR) being the mean volume expelled in 1 minute. Data were analyzed by the Shapiro-Wilk, Kolmogorov-Smirnov and Mann-Whitney tests (α = 5%) Results: Mean USFR for G1 and G2 was 0.52 mL / min and 0.66 mL / min, respectively (p>0.05) and, in both groups, significant difference was observed (p <0.05) between the mean USFR values of its subgroups, and values of adolescents being higher than those of children Conclusion: There is no difference in unstimulated salivary flow of pediatric cancer patients before starting antineoplastic treatment compared with healthy pediatric patients.

INTRODUÇÃO: A má oclusão, definida como alteração do crescimento e do desenvolvimento que afeta a oclusão dentária, é considerada um problema de saúde pública, pois apresenta alta prevalência e interfere negativamente na qualidade de vida das pessoas. OBJETIVO: Avaliar a prevalência de más oclusões em escolares de 7 a 9 anos de idade do Pólo 1 da Rede Municipal de Ensino de João Pessoa-PB. MATERIAL E MÉTODO: Foi realizado um estudo transversal com 162 escolares, selecionados de forma probabilística, de ambos os gêneros. Dentre as características da oclusão, foram observados: relação molar de Angle, sobressaliência, sobremordida, mordida aberta anterior, mordida cruzada e apinhamento. Os dados foram coletados por examinador calibrado (Kappa = 0,93), organizados em programa SPSS 13.0 e submetidos à análise descritiva e ao teste Qui-quadrado, com nível de significância de 5%. RESULTADO: 89,5% dos escolares apresentaram algum tipo de má oclusão; 48,1% da amostra foi classificada como tendo relação molar de Classe I, 32,1% Classe II e 17,9% Classe III. O apinhamento foi a má oclusão mais frequente (67,3%), seguido da sobressaliência acentuada (48,8%), sobremordida acentuada (41,9%), mordida cruzada posterior (11,7%), mordida cruzada anterior (11,7%) e mordida aberta anterior (11,7%). A mordida cruzada posterior foi estatisticamente mais frequente no gênero masculino e a sobressaliência acentuada apresentou associação com a Classe II de Angle. CONCLUSÃO: A população em tela apresentou alta prevalência de alterações oclusais, o que indica a necessidade de intervenção precoce, seja com programas preventivos e educativos, seja com programas de assistência.

INTRODUCTION: Malocclusion, defined as change in growth and development that affects dental occlusion, is considered a public health problem, because of its high prevalence and negative impact on quality of life. OBJECTIVE: Assess the prevalence of malocclusion in children 7-9 years old from Pole 1 of the municipal schools in João Pessoa-PB. MATERIAL AND METHOD: A cross-sectional study was conducted with a probabilistic random sample of 162 schoolchildren of both genders. The following oclusal findings were observed: molar classes, overjet, overbite, anterior open bite, crossbite and crowding. Data were collected by a calibrated examiner (Kappa = 0.93), organized by the SPSS 13.0 and subjected to descriptive analysis and chi-square test, with a significance level of 5%. RESULT: 89.5% of schoolchildren had some type of malocclusion. 48.1% of the sample were classified as having Class I, 32.1% Class II and 17.9% Class III. The crowding was the most frequent malocclusion (67.3%), followed by increased overjet (48.8%), increased overbite (41.9%), posterior crossbite (11.7%), anterior crossbite (11.7%) and anterior open bite (11.7%). A posterior crossbite was statistically more frequent in males. Class II was associated with increased overjet. CONCLUSION: This population presented high prevalence of malocclusion, which indicates the need for early intervention, with preventive and educational programs or assistance.