RESUMO Objetivos. Avaliar a tendência da mortalidade neonatal, pós-neonatal e infantil de 1996 a 2020, na região metropolitana do estado do Rio de Janeiro e nas outras regiões. Métodos. Estudo ecológico utilizando regiões como unidade de análise. Os dados foram acessados no Sistema de Informações sobre Mortalidade e Sistema de Informações sobre Nascidos Vivos da Capital (Rio de Janeiro), dos territórios vizinhos (Niterói, São Gonçalo e Baixada Fluminense) e das outras regiões do Estado do Rio de Janeiro. Utilizamos a modelagem multinível de Poisson, onde as variáveis de resposta dos modelos foram mortalidade infantil e seus componentes neonatal e pós-neonatal. Os efeitos fixos dos modelos ajustados foram região e ano da morte. Resultados. No período 1996-2020, a Baixada Fluminense apresentou a maior taxa de mortalidade infantil de seus componentes neonatal e pós-natal na região metropolitana. Todos os modelos ajustados mostraram que quanto mais recente o ano, menor o risco de mortalidade. O risco ajustado da mortalidade infantil e seus componentes neonatal e pós-neonatal foi menor em Niterói. Conclusão. A Baixada Fluminense apresentou o maior risco de mortalidade infantil e de seus componentes neonatal e pós-neonatal na região metropolitana. Detectamos estabilização das taxas de mortalidade nos últimos anos. Objetivos pósneonatal pós 199 2020 Métodos análise Janeiro, , Janeiro) Niterói, Niterói (Niterói Poisson pósneonatal. neonatal. morte Resultados 19962020, 19962020 1996-2020 pósnatal natal Conclusão anos 19 202 1996202 1996-202 1 20 199620 1996-20 2 19962 1996-2 1996-

ABSTRACT Objectives. The study aims to assess the trend of neonatal, post-neonatal, and infant mortality from 1996 to 2020 within the metropolitan region of the state of Rio de Janeiro and other regions. Methods. Ecological study using the region as analysis unity. Data were accessed from the Mortality Information System and Live Birth Information System in the capital Rio de Janeiro, in the neighboring areas of Niterói, São Gonçalo, Baixada Fluminense, and the remaining regions of the state of Rio de Janeiro State. We applied Poisson multilevel modeling, where the models’ response variables were infant mortality and its neonatal and post neonatal components. Fixed effects of the adjusted models were region and death year variables. Results. During the 1996-2020 period, the Baixada Fluminense showed the highest infant mortality rate as to its neonatal and post neonatal components. All adjusted models showed that the more recent the year the lower the mortality risk. Niterói showed the lowest adjusted risk of infant mortality and its neonatal and post neonatal components. Conclusion. Baixada Fluminense showed the highest mortality risk for infant mortality and its neonatal and post-neonatal components in the metropolitan region. The stabilization in mortality rates in recent years was identified by the research. Objectives postneonatal, postneonatal 199 202 Methods unity Gonçalo State modeling Results 19962020 1996-202 period Conclusion research 19 20 1996202 1996-20 1 2 199620 1996-2 19962 1996-

RESUMO Objetivos. Avaliar a tendência da mortalidade neonatal, pós-neonatal e infantil de 1996 a 2020, na região metropolitana do estado do Rio de Janeiro e nas outras regiões. Métodos. Estudo ecológico utilizando regiões como unidade de análise. Os dados foram acessados no Sistema de Informações sobre Mortalidade e Sistema de Informações sobre Nascidos Vivos da Capital (Rio de Janeiro), dos territórios vizinhos (Niterói, São Gonçalo e Baixada Fluminense) e das outras regiões do Estado do Rio de Janeiro. Utilizamos a modelagem multinível de Poisson, onde as variáveis de resposta dos modelos foram mortalidade infantil e seus componentes neonatal e pós-neonatal. Os efeitos fixos dos modelos ajustados foram região e ano da morte. Resultados. No período 1996-2020, a Baixada Fluminense apresentou a maior taxa de mortalidade infantil de seus componentes neonatal e pós-natal na região metropolitana. Todos os modelos ajustados mostraram que quanto mais recente o ano, menor o risco de mortalidade. O risco ajustado da mortalidade infantil e seus componentes neonatal e pós-neonatal foi menor em Niterói. Conclusão. A Baixada Fluminense apresentou o maior risco de mortalidade infantil e de seus componentes neonatal e pós-neonatal na região metropolitana. Detectamos estabilização das taxas de mortalidade nos últimos anos.

ABSTRACT Objectives. The study aims to assess the trend of neonatal, post-neonatal, and infant mortality from 1996 to 2020 within the metropolitan region of the state of Rio de Janeiro and other regions. Methods. Ecological study using the region as analysis unity. Data were accessed from the Mortality Information System and Live Birth Information System in the capital Rio de Janeiro, in the neighboring areas of Niterói, São Gonçalo, Baixada Fluminense, and the remaining regions of the state of Rio de Janeiro State. We applied Poisson multilevel modeling, where the models’ response variables were infant mortality and its neonatal and post neonatal components. Fixed effects of the adjusted models were region and death year variables. Results. During the 1996-2020 period, the Baixada Fluminense showed the highest infant mortality rate as to its neonatal and post neonatal components. All adjusted models showed that the more recent the year the lower the mortality risk. Niterói showed the lowest adjusted risk of infant mortality and its neonatal and post neonatal components. Conclusion. Baixada Fluminense showed the highest mortality risk for infant mortality and its neonatal and post-neonatal components in the metropolitan region. The stabilization in mortality rates in recent years was identified by the research.

SUMMARY OBJECTIVE: This study aimed to describe the current situation of sexual aggression and assess the adhesion to ambulatory care follow-up. METHODS: This is a cross-sectional study involving female children and adolescents aged 0–19 years, treated at the Center for Multiprofessional Care of Sexual Violence of the General Hospital of Nova Iguaçu, from 2014 to 2018. RESULTS: Of the 453 children and adolescents, 264 (58.3%) were <14 years of age and 189 (41.7%) were 14–19 years of age. In both groups, 78% were black. School delay of >2 years was found in 15.6% of children in the age group <14 years and 40.5% of adolescents in the age group 14–19 years [p<0.001; OR=3.7 (2.1–65)]. In girls aged £13 years, abuse usually occurred at home (73.2%), which was perpetrated by one aggressor (91%) and known to the victim (91.2%). In adolescents aged ≥14 years, 84.1% of rapes occurred outside the home, practiced by one aggressor (74.8%), 57.8% were unknown, and in 91.2% of cases, there was use of physical force and/or verbal threats. The victims aged <14 years have 14 times more chance of experiencing aggression within the family setting [p<0.001; OR=14.3 (8.2–25.6)] and 16 times more chance of experiencing aggression from known persons [p<0.001; OR=16.2 (9.2–29.8)]. On the contrary, adolescents aged ≥14 years have three times more chance of being abused by more than one aggressor [p<0.001; OR=3.3 (1.8–6.1)]. CONCLUSION: Black girls, especially those aged <14 years, are in a situation of greater vulnerability for sexual violence, have less adhesion to follow-up, and often experience aggression in the household setting. OBJECTIVE followup. followup follow up. up follow-up METHODS crosssectional cross sectional 019 0 19 0–1 Iguaçu 201 2018 RESULTS 45 26 58.3% 583 58 3 (58.3% <1 18 41.7% 417 41 7 (41.7% 1419 14–1 groups 78 black 2 > 156 15 6 15.6 405 40 5 40.5 p<0.001 p0001 p 001 [p<0.001 OR37 OR OR=3. 2.1–65. 2165 2.1–65 . 1 65 (2.1–65)] 13 £1 73.2%, 732 73.2% , 73 (73.2%) 91% 91 (91% 91.2%. 912 (91.2%) ≥1 841 84 84.1 74.8%, 748 74.8% 74 8 (74.8%) 578 57 57.8 unknown 91.2 cases andor or threats OR143 OR=14. 8.2–25.6 82256 25 (8.2–25.6) OR162 OR=16. 9.2–29.8. 92298 9.2–29.8 9 29 (9.2–29.8)] contrary OR33 1.8–6.1. 1861 1.8–6.1 (1.8–6.1)] CONCLUSION violence followup, up, 01 0– 20 4 58.3 (58.3 < 41.7 (41.7 141 14– 15. 40. p<0.00 p000 00 [p<0.00 OR3 OR=3 216 2.1–6 (2.1–65) £ 73.2 (73.2% (91 (91.2% ≥ 84. 74.8 (74.8% 57. 91. OR14 OR=14 8.2–25. 8225 (8.2–25.6 OR16 OR=16 9229 9.2–29. (9.2–29.8) 186 1.8–6. (1.8–6.1) 58. (58. 41. (41. p<0.0 p00 [p<0.0 OR= 21 2.1– (2.1–65 73. (73.2 (9 (91.2 74. (74.8 OR1 OR=1 8.2–25 822 (8.2–25. 922 9.2–29 (9.2–29.8 1.8–6 (1.8–6.1 (58 (41 p<0. p0 [p<0. 2.1 (2.1–6 (73. ( (91. (74. 8.2–2 82 (8.2–25 92 9.2–2 (9.2–29. 1.8– (1.8–6. (5 (4 p<0 [p<0 2. (2.1– (73 (74 8.2– (8.2–2 9.2– (9.2–29 1.8 (1.8–6 p< [p< (2.1 (7 8.2 (8.2– 9.2 (9.2–2 1. (1.8– [p (2. 8. (8.2 9. (9.2– (1.8 (2 (8. (9.2 (1. (8 (9. (1

Resumo O objetivo deste estudo é caracterizar a morbidade da COVID-19 no ano de 2020, identificando as áreas mais vulneráveis e áreas de aglomeração de casos em uma favela do Rio de Janeiro/Brasil conhecida como Manguinhos. Trata-se de um estudo descritivo transversal realizado de 16 de março a 12 de agosto de 2020. Descrevemos o perfil sociodemográfico dos casos e fizemos análise espacial por meio de mapas de pontos e Kernel. As taxas de incidência foram calculadas por sexo, idade e sub-regiões. A taxa de incidência foi de 202/10.000 habitantes. Detectamos aglomerados de casos a oeste, centro-norte e centro-sul de Manguinhos. Altas taxas de incidência foram observadas também nas sub-regiões centro-norte, centro-sul e sudoeste. Nas sub-regiões com alta incidência, o percentual de pessoas dependentes de ajuda financeira governamental variou entre 13% e 21%. As sub-regiões com maior aglomeração de casos no território de Manguinhos coincidem com as regiões com as maiores taxas de incidência, mas não com as regiões mais pobres do território. COVID19 COVID 19 COVID-1 2020 JaneiroBrasil Janeiro Brasil Tratase Trata se 1 Kernel sexo subregiões. subregiões sub regiões. 20210000 202 10 000 202/10.00 habitantes oeste centronorte centro norte centrosul sul centronorte, norte, sudoeste 13 21 21% COVID1 COVID- 2021000 20 00 202/10.0 2 202100 0 202/10. 20210 202/10 2021 202/1 202/

Abstract This study aims to characterize the morbidity of COVID-19 in the year 2020 by identifying the most vulnerable areas and areas of clustering of cases in a favela from Rio de Janeiro/Brazil known as Manguinhos. This is a cross-sectional descriptive study performed from March 16, 2020, to August 12, 2020. We described the sociodemographic profile of the cases and performed spatial analysis using point and Kernel maps. Incidence rates were calculated by sex, age, and sub-regions. The incidence rate was 202/10,000. We detected clusters of cases west, central-north, and central-south of Manguinhos. High incidence rates were observed also in sub-regions of central-north, central-south, and southwest. In the sub-regions with high incidence, the percentage of people depending on financial governmental aid ranged between 13% and 21%. The sub-regions with the highest agglomeration of cases in the territory of Manguinhos coincide with the regions with the highest incidence rates, but not with the poorest regions of the territory. COVID19 COVID 19 COVID-1 202 JaneiroBrazil Janeiro Brazil crosssectional cross sectional 16 12 maps sex age subregions. subregions sub regions. 20210000 10 000 202/10,000 west centralnorth, centralnorth central north, north central-north centralsouth south centralsouth, south, southwest 13 21 21% COVID1 1 COVID- 20 2021000 00 202/10,00 2 202100 0 202/10,0 20210 202/10, 2021 202/10 202/1 202/

Abstract This study aimed to analyze the accuracy of two methods for detecting halitosis, the organoleptic assessment by a trained professional (OA) with volatile sulfur compounds (VSC) measurement via Halimeter® (Interscan Corporation) and information obtained from a close person (ICP). Methodolody Participants were patients and companions who visited a university hospital over one year period to perform digestive endoscopy. A total of 138 participants were included in the VSC test, whose 115 were also included in the ICP test. ROC curves were constructed to establish the best VSC cut-off points. Results The prevalence of halitosis was 12% (95%CI: 7% to 18%) and 9% (95%CI 3% to 14%) for the OA and ICP, respectively. At the cut-off point >80 parts per billion (ppb) VSC, the prevalence of halitosis was 18% (95%CI: 12% to 25%). At the cut-off point >65 ppb VSC, sensitivity and specificity were 94% and 76%, respectively. At the cut-off point >140 ppb, sensitivity was 47% and specificity 96%. For the ICP, sensitivity was 14% and specificity 92%. Conclusions VSC presents high sensitivity at the cut-off point of >65 ppb and high specificity at the cut-off point of >140 ppb. ICP had high specificity, but low sensitivity. The OA can express either occasional or chronic bad breath, whereas the ICP can be a potential instrument to detect chronic halitosis. (OA (VSC Halimeter Interscan Corporation ICP. . (ICP) endoscopy 13 test 11 cutoff cut off points 12 95%CI 95CI CI 95 7 18 9 3 14 respectively 80 >8 (ppb 25%. 25 25% 25%) 65 >6 94 76 76% 140 >14 47 96 96% 92 92% breath (ICP 1 8 > 2 6 >1 4

SUMMARY OBJECTIVE: The aim of this study was to assess the rate of repeated pregnancy in adolescence and its association with early marriage and education level. METHODS: This is a cross-sectional study conducted by searching the Live Births Data System. The study included all adolescents in the age group 10–19 years with live births from 2015 to 2019 (n=2,405,248), divided into three groups: G1: primiparas; G2: with 1 previous pregnancy; and G3: with two or more previous pregnancies. RESULTS: Total repeated pregnancies remained stable, along the years. In the age group 10–14 years, the decrease in the period was from 5.0 to 4.7%, whereas in the age group 15–19 years, it was from 27.8 to 27.3%. Being married or in a stable union increases by 96% the chance of repeated pregnancy in the age group 10–14 years (p<0.001; OR=1.96; 95% confidence interval [CI] 1.85–2.09). In the age group 15–19 years, the chance of repeated pregnancy among the married or in stable union increased 40% (p<0.001; OR=1.40; 95%CI 1.39–1.41)). Girls aged 10–14 years with an education level of<8 years had a 64% higher chance of repeated pregnancy (p<0.001; OR=1.64; 95%CI 1.53–1.75), and among those aged 15–19 years, there was a 137% higher chance of repeated pregnancy (p<0.001; OR=2.37; 95%CI 2.35–2.38). CONCLUSION: Repeated pregnancy in adolescence in Brazil remains very high over the years. There is an association between low education level and early marriage with repeated pregnancies in adolescence. OBJECTIVE METHODS crosssectional cross sectional System 1019 10 19 10–1 201 n=2,405,248, n2405248 n n=2,405,248 , 2 405 248 (n=2,405,248) groups G1 G primiparas G2 G3 RESULTS 1014 14 50 5 0 5. 47 4 7 4.7% 1519 15 15–1 278 27 8 27. 273 3 27.3% 96 p<0.001 p0001 p 001 (p<0.001 OR=1.96 OR196 OR 95 CI [CI 1.85–2.09. 185209 1.85–2.09 . 85 09 1.85–2.09) 40 OR=1.40 OR140 95CI 1.39–1.41. 139141 1.39–1.41 39 41 1.39–1.41)) of8 of< 64 OR=1.64 OR164 1.53–1.75, 153175 1.53–1.75 53 75 1.53–1.75) 137 OR=2.37 OR237 37 2.35–2.38. 235238 2.35–2.38 35 38 2.35–2.38) CONCLUSION 101 10– 20 n240524 n=2,405,24 24 (n=2,405,248 4.7 151 15– 27.3 9 p<0.00 p000 00 (p<0.00 OR=1.9 OR19 18520 1.85–2.0 OR=1.4 OR14 13914 1.39–1.4 1.39–1.41) 6 OR=1.6 OR16 15317 1.53–1.7 13 OR=2.3 OR23 23523 2.35–2.3 n24052 n=2,405,2 (n=2,405,24 4. p<0.0 p00 (p<0.0 OR=1. OR1 1852 1.85–2. 1391 1.39–1. 1531 1.53–1. OR=2. OR2 2352 2.35–2. n2405 n=2,405, (n=2,405,2 p<0. p0 (p<0. OR=1 185 1.85–2 139 1.39–1 153 1.53–1 OR=2 235 2.35–2 n240 n=2,405 (n=2,405, p<0 (p<0 OR= 18 1.85– 1.39– 1.53– 23 2.35– n24 n=2,40 (n=2,405 p< (p< 1.85 1.39 1.53 2.35 n2 n=2,4 (n=2,40 (p 1.8 1.3 1.5 2.3 n=2, (n=2,4 1. 2. n=2 (n=2, n= (n=2 (n= (n

Abstract Halitosis affects all populations worldwide. The presence of chronic halitosis may be related to a health problem. Patients with bad breath usually seek a gastroenterologist and, in some cases, invasive and expensive exams, such as digestive endoscopy, are performed to investigate the etiology of halitosis. This study aimed to investigate whether the prevalence of bad breath in patients diagnosed with dyspepsia (any pain or discomfort in the upper abdomen) is higher than or equivalent to that in non-dyspeptic patients. This is a cross-sectional study that included 312 patients from university hospitals in the city of Rio de Janeiro (141 dyspeptic patients and 171 non-dyspeptic ones). The presence of halitosis was defined based on different cutoff points. Association analyses were performed using a log-binomial model and 95% confidence intervals were calculated for the coefficients, adjusting for sex and age. The equivalence test (Westlake) was used to test the hypothesis of equivalence between the proportions of patients with bad breath in the two groups (dyspeptic vs. non-dyspeptic), considering an equivalence band of ± 15%. The prevalence of bad breath ranged from 30% to 64% according to the definition of bad breath. Dyspepsia was not associated with bad breath in any of the three definitions of bad breath (two specific ones and a sensitive one). The proportion of patients with marked bad breath was equivalent in patients with and without dyspepsia. worldwide problem cases exams endoscopy abdomen nondyspeptic non crosssectional cross sectional 31 141 (14 17 ones. . ones) points logbinomial log binomial 95 coefficients age Westlake (Westlake vs nondyspeptic, , non-dyspeptic) 15 15% 30 64 one. one one) 3 14 (1 1 9 6 (

Resumo O objetivo deste estudo é caracterizar a morbidade da COVID-19 no ano de 2020, identificando as áreas mais vulneráveis e áreas de aglomeração de casos em uma favela do Rio de Janeiro/Brasil conhecida como Manguinhos. Trata-se de um estudo descritivo transversal realizado de 16 de março a 12 de agosto de 2020. Descrevemos o perfil sociodemográfico dos casos e fizemos análise espacial por meio de mapas de pontos e Kernel. As taxas de incidência foram calculadas por sexo, idade e sub-regiões. A taxa de incidência foi de 202/10.000 habitantes. Detectamos aglomerados de casos a oeste, centro-norte e centro-sul de Manguinhos. Altas taxas de incidência foram observadas também nas sub-regiões centro-norte, centro-sul e sudoeste. Nas sub-regiões com alta incidência, o percentual de pessoas dependentes de ajuda financeira governamental variou entre 13% e 21%. As sub-regiões com maior aglomeração de casos no território de Manguinhos coincidem com as regiões com as maiores taxas de incidência, mas não com as regiões mais pobres do território.

Abstract This study aims to characterize the morbidity of COVID-19 in the year 2020 by identifying the most vulnerable areas and areas of clustering of cases in a favela from Rio de Janeiro/Brazil known as Manguinhos. This is a cross-sectional descriptive study performed from March 16, 2020, to August 12, 2020. We described the sociodemographic profile of the cases and performed spatial analysis using point and Kernel maps. Incidence rates were calculated by sex, age, and sub-regions. The incidence rate was 202/10,000. We detected clusters of cases west, central-north, and central-south of Manguinhos. High incidence rates were observed also in sub-regions of central-north, central-south, and southwest. In the sub-regions with high incidence, the percentage of people depending on financial governmental aid ranged between 13% and 21%. The sub-regions with the highest agglomeration of cases in the territory of Manguinhos coincide with the regions with the highest incidence rates, but not with the poorest regions of the territory.

Resumo Este estudo teve como objetivo analisar o papel de fatores temporais, geográficos e sociodemográficos na mortalidade por câncer de próstata, mama, colo do útero, cólon, pulmão e esôfago nas capitais brasileiras (2000-2015). Estudo ecológico utilizando informações brasileiras de mortalidade. Modelos de Poisson multinível foram usados para estimar o risco ajustado de mortalidade por câncer. Os níveis de mortalidade foram maiores em homens para câncer de cólon, pulmão e esôfago. As taxas de mortalidade foram mais altas nos idosos. Nossos resultados mostraram risco aumentado de mortalidade por câncer de cólon em ambos os sexos de 2000 a 2015, o que também foi evidenciado para câncer de mama e de pulmão em mulheres. Em ambos os sexos, o maior risco de mortalidade para câncer de pulmão e esôfago foi observado nas capitais do Sul. As capitais do Centro-Oeste, Sul e Sudeste apresentaram o maior risco de mortalidade por câncer de cólon tanto para homens quanto para mulheres. A taxa de mortalidade por câncer de cólon aumentou para ambos os sexos, enquanto a mortalidade por câncer de mama e de pulmão aumentou apenas para as mulheres. A região Norte apresentou a menor taxa de mortalidade por câncer de mama, colo do útero, cólon e esôfago. As regiões Centro-Oeste e Nordeste apresentaram as maiores taxas de mortalidade por câncer de próstata.

Abstract This study aimed to analyze the role of period, geographic and socio demographic factors in cancer-related mortality by prostate, breast, cervix, colon, lung and esophagus cancer in Brazilians capitals (2000-2015). Ecological study using data of Brazilian Mortality Information. Multilevel Poisson models were used to estimate the adjusted risk of cancer mortality. Mortality rate levels were higher in males for colon, lung and esophageal cancers. Mortality rates were highest in the older. Our results showed an increased risk of colon cancer mortality in both sexes from 2000 to 2015, which was also evidenced for breast and lung cancers in women. In both genders, the highest mortality risk for lung and esophageal cancers was observed in Southern capitals. Midwestern, Southern and Southeastern capitals showed the highest mortality risk for colon cancer both for males and females. Colon cancer mortality rate increased for both genders, while breast and lung cancers mortality increased only for women. The North region showed the lowest mortality rate for breast, cervical, colon and esophageal cancers. The Midwest and Northeast regions showed the highest mortality rates for prostate cancer.

Resumo Este estudo teve como objetivo analisar o papel de fatores temporais, geográficos e sociodemográficos na mortalidade por câncer de próstata, mama, colo do útero, cólon, pulmão e esôfago nas capitais brasileiras (2000-2015). Estudo ecológico utilizando informações brasileiras de mortalidade. Modelos de Poisson multinível foram usados para estimar o risco ajustado de mortalidade por câncer. Os níveis de mortalidade foram maiores em homens para câncer de cólon, pulmão e esôfago. As taxas de mortalidade foram mais altas nos idosos. Nossos resultados mostraram risco aumentado de mortalidade por câncer de cólon em ambos os sexos de 2000 a 2015, o que também foi evidenciado para câncer de mama e de pulmão em mulheres. Em ambos os sexos, o maior risco de mortalidade para câncer de pulmão e esôfago foi observado nas capitais do Sul. As capitais do Centro-Oeste, Sul e Sudeste apresentaram o maior risco de mortalidade por câncer de cólon tanto para homens quanto para mulheres. A taxa de mortalidade por câncer de cólon aumentou para ambos os sexos, enquanto a mortalidade por câncer de mama e de pulmão aumentou apenas para as mulheres. A região Norte apresentou a menor taxa de mortalidade por câncer de mama, colo do útero, cólon e esôfago. As regiões Centro-Oeste e Nordeste apresentaram as maiores taxas de mortalidade por câncer de próstata.

Abstract This study aimed to analyze the role of period, geographic and socio demographic factors in cancer-related mortality by prostate, breast, cervix, colon, lung and esophagus cancer in Brazilians capitals (2000-2015). Ecological study using data of Brazilian Mortality Information. Multilevel Poisson models were used to estimate the adjusted risk of cancer mortality. Mortality rate levels were higher in males for colon, lung and esophageal cancers. Mortality rates were highest in the older. Our results showed an increased risk of colon cancer mortality in both sexes from 2000 to 2015, which was also evidenced for breast and lung cancers in women. In both genders, the highest mortality risk for lung and esophageal cancers was observed in Southern capitals. Midwestern, Southern and Southeastern capitals showed the highest mortality risk for colon cancer both for males and females. Colon cancer mortality rate increased for both genders, while breast and lung cancers mortality increased only for women. The North region showed the lowest mortality rate for breast, cervical, colon and esophageal cancers. The Midwest and Northeast regions showed the highest mortality rates for prostate cancer.

RESUMO Em países desenvolvidos, a utilização de recursos tecnológicos digitais é considerada uma ferramenta potente para o enfrentamento da Covid-19. No entanto, no Brasil, a implantação desses recursos nas unidades de saúde ainda é bastante deficitária e não priorizada pela gestão. O propósito deste trabalho é relatar a experiência de implantação do aplicativo InfoSaúde, iniciada em julho de 2020, na atenção primária, para a otimização das ações direcionadas ao controle da Covid-19 em uma comunidade vulnerável. A definição dos requisitos do aplicativo e dos fluxos operacionais foram obtidos por meio de questionários padronizados para os profissionais de saúde e usuários, resultando em três macroprocessos: Prevenção, Atendimento e Monitoramento, testados e validados pelos profissionais e usuários, e com interface ao sistema de informação da unidade. Os resultados encontrados foram: a) Retorno às ações de prevenção com informação a distância; b) Agilização das intervenções pela integração de setores de: Assistência, Laboratório e Vigilância; redução da sobrecarga de trabalho e risco ocupacional com atividades a distância; e c) Melhoria no sistema de informação e capacidade de intervenção precoce a distância. A implantação de recurso tecnológico simples na atenção primária é factível, contribuindo para integralidade do cuidado, redução do risco ocupacional e carga de trabalho.

ABSTRACT In developed countries, the use of digital technological resources is a powerful tool to face COVID-19. However, in Brazil, the implementation of these resources in the public health clinics is still very deficient and not prioritized by the management. The purpose of this paper is to report the experience of implementing the InfoSaúde application, started in July 2020, in primary care, for the optimization of actions aimed at controlling COVID-19 in a vulnerable community. The definition of application requirements and operational flows was based by standardized questionnaires for health professionals and users, which resulted in three macro-processes: Prevention, Care and Monitoring, tested and validated by professionals and users with an interface to the clinic’s information system. The results were as follows: a) Return to prevention actions with remote information; b) Streamlining interventions by integrating the Assistance, Laboratory and Surveillance sectors; reduction of work overload and occupational risk with distance activities and, c) Improvement in the information system and capacity for early intervention at a distance. The implementation of a simple technological resource in primary care is feasible, contributing to comprehensive care, reducing occupational risk, and workload.

SUMMARY OBJECTIVE: This study aimed to evaluate the frequency of late pregnancies in Brazil, the age-specific fertility rate (ASFR) in the regions, the rate of prematurity, and the rate of low birth weight (LBW) and their association with advanced maternal age compared with 20–34-year-old women. METHODS: This was a cross-sectional study conducted by searching the Information System on Live Births (Sistema de Informações Sobre Nascidos Vivos [SINASC]). Data from 1995 to 2018 were collected, and pregnant women were divided into three categories based on their age range: 35–39, 40–44, and ≥45 years. The study calculated the frequency of deliveries of mothers of advanced age in Brazil, the ASFR, and the rates of prematurity and LBW in each group. RESULTS: The frequency of newborns (NB) of mothers aged ≥35 years increased by 64%. The 35–39-year-old ASFR increased in all regions, except in the northeast. At maternal age ≥35 years, NB increased by 58% between 28 and 36 weeks during the study period. LBW increased between 500 and 1,499 g in 68.7% and between 1,500 and 2499 g in 57% of cases. In 2018, regarding the age range of 20–34 years, the chance of premature delivery was 29% at 35–39 years (OR=1.29), 54% higher at 40–44 years (OR=1.54), and 114% higher at ≥45 years (OR=2.14); while the chance of LBW increased by 28% at 35–39 years (OR=1.28), 56% at 40–44 years (OR=1.56), and 139% at 45 years or older (OR=2.39). CONCLUSIONS: The frequency of deliveries and ASFR ≥35 years increased between 1995 and 2018. The chances of prematurity and LBW were higher with increased maternal age.

SUMMARY OBJECTIVE: This study aimed to assess live birth frequency and age-specific fertility rates (ASFR) in the period 1996–2018 and the number of pregnancies at <14 years old in the period 2012–2018. METHODS: This was a cross-sectional study conducted by search on Live Births Data System (SINASC/DATASUS) database. RESULTS: There was a variation in ASFR in Brazil of 0.78‰ in 1996 to 0.87‰ in 2018 (+11.5%). In the north region, it increased from 1.28‰ to 1.66‰ in 2018. In the northeast region, it increased from 0.72‰ to 1.66‰ (+131%) in 1996–2011, but decreased to 1.31‰ in 2018 (-21% in relation to 2011). When comparing 1996 and 2018, in the southeast region, there was a 22% decrease; in the south region, it was 48.2%; and in the Center-West region, it was 34%; but in the north region, there was a 29.7% increase, and in the northeast region, it was 81.9%. When adding girls who became pregnant aged 13 years and gave birth at 14, there was a threefold increase in the rate. CONCLUSIONS: The increase of pregnancies in <14 years old in less developed regions of Brazil shows an association with socioeconomic factors and reveals the severe problem of rape of vulnerable persons in the country.

SUMMARY OBJECTIVE: The aim of this study was to evaluate the frequency of teenage pregnancy in all Brazilian regions and states in the period of 2000-2019 among two age groups, namely, 10-14 and 15-19 years old, and correlate it with the human development index. METHODS: A cross-sectional study was performed by using the data from the Live Birth Info System from the National Health System’s database. RESULTS: The percentage of live births from teenage mothers (age 10-19 years) in Brazil decreased by 37.2% (i.e., 23.4 in 2000 to 14.7% in 2019) in all regions. Amazonas and Maranhão were the only states to show increased fertility rates for teens in the age group of 10-14 years. The fertility index decreased from 80.9-48% in all states among mothers aged 15-19 years. Only the Southeast and South regions showed levels below the Brazilian average (i.e., 38.2 and 39%, respectively). The proportion of live birth showed an inversely proportional trend to the human development index score. CONCLUSIONS: Brazil shows a decline in the percentage of live birth among adolescent mothers and the fertility rate. Live birth is inversely proportional to the human development index score. However, the teenage pregnancy numbers are still high, with great regional inequality in the country.