Abstract At low concentrations used for in-office bleaching gels, such as 6% HP, gingival barrier continues to be performed. If we take into account that, in the at-home bleaching technique, no barrier is indicated, it seems that the use of a gingival barrier fails to make much sense when bleaching gel in low concentration is used for in-office bleaching. Objective This double-blind, split-mouth, randomized clinical trial evaluated the gingival irritation (GI) of in-office bleaching using 6% hydrogen peroxide (HP) with and without a gingival barrier in adolescents, as well as color change and the impact of oral condition on quality of life. Methodology Overall, 60 participants were randomized into which side would or would not receive the gingival barrier. In-office bleaching was performed for 50 minutes with 6% HP in three sessions. The absolute risk and intensity of GI were assessed with a visual analogue scale. Color change was assessed using a digital spectrophotometer and color guides. The impact of oral condition on quality of life was assessed using the Brazilian version of the Oral Health Impact Profile (α=0.05). Results The proportion of patients who presented GI for the “with barrier” group was 31.6% and for the “without barrier” group, 30% (p=1.0). There is an equivalence for the evaluated groups regarding GI intensity (p<0.01). Color change was detected with no statistical differences (p>0.29). There was a significant impact of oral condition on quality of life after bleaching (p<0.001). Conclusions The use or not of the gingival barrier for in-office bleaching with 6% HP was equivalent for GI, as well as for bleaching efficacy, with improvement in the impact of oral condition on quality of life. inoffice office gels 6 athome at home technique indicated doubleblind, doubleblind double blind, blind double-blind splitmouth, splitmouth split mouth, mouth split-mouth (GI (HP adolescents Overall Inoffice In 5 sessions scale guides α=0.05. α005 α α=0.05 . 0 05 (α=0.05) 316 31 31.6 30 p=1.0. p10 p p=1.0 1 (p=1.0) p<0.01. p001 p<0.01 01 (p<0.01) p>0.29. p029 p>0.29 29 (p>0.29) p<0.001. p0001 p<0.001 001 (p<0.001) efficacy α00 α=0.0 (α=0.05 3 31. p1 p=1. (p=1.0 p00 p<0.0 (p<0.01 p02 p>0.2 2 (p>0.29 p000 p<0.00 00 (p<0.001 α0 α=0. (α=0.0 p=1 (p=1. p0 p<0. (p<0.0 p>0. (p>0.2 (p<0.00 α=0 (α=0. p= (p=1 p<0 (p<0. p>0 (p>0. α= (α=0 (p= p< (p<0 p> (p>0 (α= (p (p< (p> (α

Resumo Embora a literatura tenha observado variações na permeabilidade do peróxido de hidrogênio (PH) e, consequentemente, na sensibilidade dental entre diferentes tipos de dentes anteriores, há escassez de pesquisas sobre esse tema específico. Este estudo teve como objetivo avaliar a permeabilidade do PH e a mudança da cor (MC) em diferentes grupos de dentes anteriores superiores humanos (caninos, incisivos laterais e incisivos centrais) após clareamento de consultório com PH a 35%. Trinta dentes anteriores superiores (n=10) foram clareados com gel de PH a 35% numa sessão de três aplicações de 15 minutos. A espessura vestibular (mm) foi medida em imagens de tomografia computadorizada de feixe cônico. A concentração de HP (µg/mL) na câmara pulpar foi avaliada por espectrofotometria UV-Vis. A MC (WID, ∆Eab e ∆E00) foi avaliada antes e após o clareamento com espectrofotômetro digital. Aplicou-se ANOVA unidirecional e teste de Tukey para avaliar estatisticamente os dados de espessura bucal, permeabilidade PH e MC (α=0,05). A comparação entre espessura versus permeabilidade PH foi realizada com correlação de Pearson. Dentes mais grossos, como os caninos, apresentaram menor quantidade de HP no interior da câmara pulpar do que os incisivos centrais e laterais. Apesar da espessura vestibular afetar significativamente a permeabilidade do PH (p<0,05), não foram encontradas correlações entre ambos os fatores. A MC foi semelhante, independente do tipo de dente (p>0,05). A diferença na espessura vestibular dos dentes anteriores superiores não interfere na MC. Porém, quanto mais fina a espessura da parede vestibular, maior será a permeabilidade do PH detectada na polpa após o clareamento de consultório. (PH consequentemente específico (MC caninos (caninos 35 n=10 n10 n 10 (n=10 1 minutos mm (mm cônico µg/mL µgmL µg mL (µg/mL UVVis. UVVis UV Vis. Vis UV-Vis WID, WID (WID Eab ∆E00 E00 E digital Aplicouse Aplicou se bucal α=0,05. α005 α α=0,05 . 0 05 (α=0,05) Pearson grossos p<0,05, p005 p p<0,05 , (p<0,05) fatores semelhante p>0,05. p>0,05 (p>0,05) Porém 3 n=1 n1 (n=1 ∆E0 E0 α00 α=0,0 (α=0,05 p00 p<0,0 (p<0,05 p>0,0 (p>0,05 n= (n= ∆E α0 α=0, (α=0,0 p0 p<0, (p<0,0 p>0, (p>0,0 (n α=0 (α=0, p<0 (p<0, p>0 (p>0, α= (α=0 p< (p<0 p> (p>0 (α= (p< (p> (α (p

Abstract While the literature has noted variations in hydrogen peroxide (HP) permeability, and consequently, tooth sensitivity among different types of anterior teeth, there is a scarcity of research on this specific topic. This study evaluated HP permeability and color change (CC) in different groups of human maxillary anterior teeth (canines, lateral incisors, and central incisors) after in-office bleaching with HP at 35%. Thirty teeth maxillary anterior (n=10) were bleached with HP at 35% gel in one session of three 15-minutes applications. Buccal thickness (mm) was measured from images obtained using cone beam computed tomography. The concentration of HP (µg/mL) that reached the pulp chamber was assessed using UV-Vis spectrophotometry. CC (WID, ∆Eab, and ∆E00) was evaluated before and after bleaching with a digital spectrophotometer. One-way ANOVA and Tukey’s test were applied to statistically evaluate the data for buccal thickness, HP permeability, and CC (α=0.05). Comparison between thickness and HP permeability was performed using Pearson's correlation. Thicker teeth, such as canines, had lower HP amounts inside the pulp chamber compared to central and lateral incisors. Despite the significant effect of buccal thickness on HP permeability (p<0.05), no correlation was found between the two factors. CC was similar across tooth types (p>0.05). The difference in buccal thickness among the superior anterior teeth does not interfere with CC. However, a thinner buccal wall thickness is associated with greater HP permeability detected in the pulp after in-office bleaching. (HP consequently topic (CC canines (canines incisors inoffice office 35 n=10 n10 n 10 (n=10 15minutes minutes 15 applications mm (mm tomography µg/mL µgmL µg mL (µg/mL UVVis UV Vis spectrophotometry WID, WID (WID Eab ∆Eab ∆E00 E00 E spectrophotometer Oneway One way Tukeys Tukey s α=0.05. α005 α α=0.05 . 0 05 (α=0.05) Pearsons Pearson p<0.05, p005 p p<0.05 , (p<0.05) factors p>0.05. p>0.05 (p>0.05) However 3 n=1 n1 1 (n=1 ∆E0 E0 α00 α=0.0 (α=0.05 p00 p<0.0 (p<0.05 p>0.0 (p>0.05 n= (n= ∆E α0 α=0. (α=0.0 p0 p<0. (p<0.0 p>0. (p>0.0 (n α=0 (α=0. p<0 (p<0. p>0 (p>0. α= (α=0 p< (p<0 p> (p>0 (α= (p< (p> (α (p

Abstract This narrative review critically examines some protocols of biomimetic restorative dentistry (BRD), which supposedly outperforms traditional adhesive techniques. This review explores the origins of BRD, introduces cognitive biases influencing the adoption of BRD protocols without evidence scrutiny, and discusses nine BRD protocols. For this, we searched randomized clinical trials and systematic reviews in the literature on the PubMed, Embase, and Cochrane Library CENTRAL databases, which lead to the following conclusions about the revised protocols: 1) The use of dyes excessively removes carious dentin; 2) Aluminum oxide air abrasion contributes to overtreatment and may pose long-term health risks to dental professionals; 3) Beveling enamel in posterior teeth is technically difficult and leads to unnecessary loss of adjacent sound enamel with no evidence of its use outperforming butt-joint preparations; 4) Deactivating matrix metalloproteinases with chlorhexidine shows no clinical evidence of improving restoration longevity. 5) “Elected“ gold-standard adhesive systems perform no better than other good performing available systems; 6) Immediate dentin sealing and resin coating result in similar post-operative sensitivity and longevity of indirect fillings as delayed dentin sealing; 7) Deep margin elevation is a viable alternative to manage subgingival margins in occlusoproximal cavities; 8) The process of “decoupling” with time lacks scientific evidence to support its use; 9) Placing fiber inserts on the pulpal floor and/or axial wall to minimize stress offers no benefits over current alternatives. In conclusion, more rigorous research is needed to validate BRD protocols, focusing on important clinical outcomes that impact in the longevity of the restoration, such as fracture, debonding, post-operative sensitivity, esthetic quality, presence of caries lesions adjacent to restorations and patients’ satisfaction need to be thoroughly investigated. Reliance on anecdotal evidence, clinical experience, and common sense propagates myths and undervalues the need for a critical approach in evaluating dental techniques. , (BRD) techniques scrutiny this PubMed Embase databases 1 2 longterm long term professionals 3 buttjoint butt joint preparations 4 5 Elected “Elected goldstandard gold standard 6 postoperative post operative 7 cavities 8 decoupling “decoupling 9 andor or alternatives conclusion fracture debonding quality patients investigated experience (BRD

Resumo Este estudo teve como objetivo avaliar os efeitos da aplicação do ascorbato de sódio a 10% (AS) depois do clareamento em consultório na penetração do peróxido do hidrogênio (PH) na câmara pulpar, mudança de cor e resistência de união (RU) da interface resina-esmalte. Trinta pré-molares e trinta molares foram divididos aleatoriamente em três grupos (n = 20). Um grupo foi exposto em água deionizada (controle negativo). Os outros dois grupos foram clareados com 35% PH numa única sessão de 3x15 minutos para cada aplicação. Porém, só um grupo recebeu AS durante 10 minutos depois do clareamento. Depois, a concentração (µg/mL) do PH no interior de cada câmara pulpar foi avaliado com espectrofotometria UV-Vis. A mudança de cor (ΔEab, ΔE00 and ΔWID) foi avaliada como espectrofotômetro digital antes e depois de uma semana do clareamento. Após de cada tratamento, os molares foram restaurados e seccionados em espécimes com interface resina-esmalte para o teste de RU por microtração a uma velocidade de 1 mm/min até a fratura. Os dados da concentração de PH e RU foram analisados usando ANOVA de uma via e teste de Tukey, e a mudança de cor com o teste t (α = 0.05). A aplicação de AS melhorou significativamente a RU e reduziu a concentração de PH na câmara pulpar (p < 0.0001). A aplicação de AS interferiu significativamente na mudança de cor depois do clareamento comprado com o grupo controle (p < 0.05). A aplicação de SA a 10% depois do clareamento em consultório reduziu significativamente a penetração do PH na câmara pulpar e interferiu na mudança de cor. (AS (PH (RU resinaesmalte. resinaesmalte resina esmalte. esmalte prémolares pré n 20. 20 . 20) negativo. negativo negativo) 35 x 3x1 Porém Depois µg/mL µgmL µg mL (µg/mL UVVis. UVVis UV Vis. Vis UV-Vis ΔEab, ΔEab (ΔEab ΔE ΔE0 ΔWID tratamento mmmin mm min fratura Tukey α 0.05. 005 0.05 0 05 0.05) p 0.0001. 00001 0.0001 0001 0.0001) 2 3 3x 00 0.0 0000 0.000 000 0. 0.00

Abstract This study aimed to evaluate the effects of the application of 10% sodium ascorbate (SA) after in-office bleaching on the penetration of hydrogen peroxide (HP) into the pulp chamber, color change, and microtensile bond strength (µTBS) to the resin-enamel interface. Thirty premolars and thirty molars were randomly divided into three groups (n = 20 each). One group was exposed to deionized water (negative control). The other two groups were bleached with 35% HP in a single session for 3x15 minutes for each application. However, in only one of them, SA was applied for 10 minutes after bleaching. After, the concentration (µg/mL) of HP in each pulp chamber was evaluated by UV-Vis spectrophotometry. Color changes (ΔEab, ΔE00, and ΔWID) were evaluated with a digital spectrophotometer before and in the first week after bleaching. After treatment, molars were restored and sectioned to obtain resin-enamel interface sticks for µTBS at a crosshead speed of 1 mm/min until failure. The HP concentration and µTBS data were analyzed using one-way ANOVA and Tukey tests, and color changes were analyzed by t-tests (α = 0.05). SA application significantly improved the µTBS values and reduced the HP concentrations within the pulp chambers (p < 0.0001). The application of SA significantly interfered with the color changes after bleaching when compared to the control group (p < 0.05). Application of 10% SA after in-office bleaching successfully reduced the penetration of HP into the pulp chamber; however, it decreased color change. (SA inoffice office (HP change (µTBS resinenamel resin enamel n 2 each. . each) negative control. control) 35 x 3x1 However them µg/mL µgmL µg mL (µg/mL UVVis UV Vis spectrophotometry ΔEab, ΔEab (ΔEab ΔE00 ΔE ΔWID treatment mmmin mm min failure oneway way tests ttests t α 0.05. 005 0.05 0 05 0.05) p 0.0001. 00001 0.0001 0001 0.0001) however 3 3x ΔE0 00 0.0 0000 0.000 000 0. 0.00

RESUMO O eucalipto é uma espécie das mais cultivadas no âmbito nacional, cuja madeira é amplamente utilizada na fabricação de móveis e outros produtos derivados. Entretanto, ela está sujeita a variações por conta de mudanças na umidade e outros fatores. Para minimizar tais variações, estudaram-se alguns tratamentos de forma pouco agressiva ao meio ambiente. Assim, este trabalho analisou as propriedades físicas e químicas da madeira de clones híbridos de Eucalyptus urograndis, in natura e termicamente modificada nas temperaturas de 140, 160, 180, 200 e 220°C, com 8,5 anos de idade, plantados em Buri-SP, Brasil. A caracterização física foi realizada segundo Brito, Garcia e Bortoletto (2006) e normas da Associação Brasileira de Normas Técnicas (1997), e a caracterização química segundo as normas Technical Association of the Pulp and Paper Industry (1999). Através de análises estatísticas de regressão fatorial com significância de 5%, o fator clone não causou interferência nas propriedades analisadas; a variação que ocorreu foi por conta da temperatura utilizada; a hemicelulose foi a principal propriedade química afetada por conta da temperatura; os tratamentos mais interessantes foram os realizados até 180 °C, uma vez que não comprometeram muito as propriedades químicas da madeira e, consequentemente, não afetariam tanto suas propriedades físicas e mecânicas. nacional derivados Entretanto fatores estudaramse estudaram se ambiente Assim urograndis 140 160 20 220C C 220 220°C 85 8 5 8, idade BuriSP, BuriSP Buri SP, SP Buri-SP Brasil Brito 2006 (2006 1997, 1997 , (1997) 1999. 1999 . (1999) 5% analisadas 18 °C consequentemente mecânicas 14 16 2 22 (200 199 (1997 (1999 1 (20 19 (199 (2 (19 ( (1

ABSTRACT Eucalyptus is a species of the most cultivated in the national scope, whose wood is widely used in the manufacture of furniture and other derived products. However, it is subjected to variations due to changes in moisture and other factors. To minimize such variations, some treatments were studied in a non-environmentally aggressive manner. This work analyzed the physical and chemical properties of wood of hybrid clones of Eucalyptus urograndis, “in natura” and thermally modified at temperatures of 140, 160, 180, 200 and 220°C, with 8.5 years of age, planted in Buri-SP, Brazil. The physical characterization was performed according to Brito, Garcia and Bortoletto (2006) and Brazilian Association of Technical Standards (1997), and the chemical characterization according to Technical Association of the Pulp and Paper Industry (1999). Through statistical analysis of factorial regression with significance of 5%, the clone factor did not cause interference in the analyzed properties; the variation that occurred was due to the temperature used; the hemicellulose was the main chemical property affected by the temperature; the most interesting treatments were those performed up to 180°C, since they did not compromise much the chemical properties of the wood and, consequently, would not affect so much their physical and mechanical properties. scope products However factors nonenvironmentally non environmentally manner urograndis natura 140 160 180 20 220C C 220 220°C 85 8 5 8. age BuriSP, BuriSP Buri SP, SP Buri-SP Brazil Brito 2006 (2006 1997, 1997 , (1997) 1999. 1999 . (1999) 5% 180C 180°C consequently 14 16 18 2 22 (200 199 (1997 (1999 1 (20 19 (199 (2 (19 ( (1

Resumen Objetivo Identificar las publicaciones que abordaron el COVID-19 como accidente laboral y su notificación por parte de los trabajadores de la salud. Métodos La búsqueda para esta scoping review exploró la literatura nacional e internacional, durante el período de 2020 a 2021, en inglés, portugués y español, en las bases de datos del Portal Regional de la Biblioteca Virtual de Salud, en MEDLINE a través de PubMed, y en el Portal de Periódicos de Capes se utilizó Embase, Scopus, Web of Science, CINAHL. Los textos fueron importados a EndNote, se eliminaron los duplicados y se exportaron a la aplicación Rayyan, se incluyeron los artículos en una planilla de Excel con la clasificación/etiquetas: COVID-19 como accidente de trabajo y Notificación de COVID-19. Resultados Se identificaron 5.665 estudios, se excluyeron 2.088 duplicaciones, que dio como resultado 3.577 publicaciones, seleccionadas por título y resumen. De ellas, 3.280 no atendían los criterios de inclusión, por lo que se obtuvieron 297 artículos. De estos, 10 fueron seleccionados para análisis completo del texto porque trataban el COVID-19 como accidente de trabajo o notificación de este daño por parte de los trabajadores de la salud. Se excluyeron dos artículos porque se trataban de revisión de literatura, por lo cual permanecieron ocho como corpus de estudio. Conclusión Aunque determinados países ya reconocieron el COVID-19 como una enfermedad ocupacional, algunos trabajadores aún tienen dificultad de relacionar la infección por SARS-CoV-2 con el trabajo en la atención a la salud, caracterizándolo como un accidente laboral. Todos deben ser orientados y capacitados sobre el reconocimiento del COVID-19 como accidente laboral y notificar su ocurrencia, dado que ya existe la definición de la infección como enfermedad de notificación obligatoria. COVID19 COVID 19 COVID-1 salud internacional 202 2021 inglés español Salud PubMed Embase Scopus Science CINAHL EndNote Rayyan clasificación/etiquetas clasificaciónetiquetas clasificación etiquetas COVID19. 19. 5665 5 665 5.66 estudios 2088 2 088 2.08 duplicaciones 3577 3 577 3.57 resumen ellas 3280 280 3.28 inclusión 29 estos 1 estudio ocupacional SARSCoV2 SARSCoV SARS CoV SARS-CoV- ocurrencia obligatoria COVID1 COVID- 20 566 66 5.6 208 08 2.0 357 57 3.5 328 28 3.2 SARS-CoV 56 6 5. 0 2. 35 3. 32

Resumo Objetivo Identificar as publicações que discorreram sobre a COVID-19 como acidente laboral e sua notificação pelos trabalhadores da saúde. Métodos A busca para esta scoping review, explorou literatura nacional e internacional, no período de 2020 e 2021, em inglês, português e espanhol, nas bases de dados do Portal Regional da Biblioteca Virtual em Saúde, na MEDLINE por meio do PubMed e no Portal de Periódicos da Capes empregou-se: Embase, Scopus, Web of Science, CINAHL. Os textos foram importados para o EndNote, suprimido os duplicados e exportados para o aplicativo Rayyan, sendo feita a inclusão dos artigos em planilha Excel com os rótulos/etiquetas: COVID-19 como acidentes de trabalho e Notificação de COVID-19. Resultados Foram identificados 5.665 estudos, excluindo 2.088 duplicações, resultando 3.577 publicações, selecionadas por título e resumo. Destas, 3.280 não atendiam aos critérios de inclusão, resultando 297 artigos. Destes, 10 foram selecionados para análise completa do texto por tratarem da COVID-19 como acidente de trabalho e/ou notificação deste agravo pelos trabalhadores da saúde. Dois artigos foram excluídos por se tratar de revisão de literatura, permanecendo 8 como corpus do estudo. Conclusão Apesar de determinados países já reconhecerem a COVID-19 como doença ocupacional, alguns trabalhadores ainda apresentam dificuldades em relacionar a infecção pelo SARS-CoV-2 com o trabalho na assistência à saúde, caracterizando como acidente laboral. Todos devem ser orientados e capacitados quanto ao reconhecimento da COVID-19 como acidente laboral e notificar sua ocorrência, uma vez que já existe a definição da infecção como doença de notificação compulsória. COVID19 COVID 19 COVID-1 saúde review internacional 202 2021 inglês espanhol Saúde empregouse empregou empregou-se Embase Scopus Science CINAHL EndNote Rayyan rótulos/etiquetas rótulosetiquetas rótulos etiquetas COVID19. 19. 5665 5 665 5.66 estudos 2088 2 088 2.08 duplicações 3577 3 577 3.57 resumo Destas 3280 280 3.28 29 Destes 1 eou ou estudo ocupacional SARSCoV2 SARSCoV SARS CoV SARS-CoV- ocorrência compulsória COVID1 COVID- 20 566 66 5.6 208 08 2.0 357 57 3.5 328 28 3.2 SARS-CoV 56 6 5. 0 2. 35 3. 32

Abstract Objective To identify the publications that discussed COVID-19 as an occupational injury and its notification by health workers. Methods The search for this scoping review explored national and international literature, between 2020 and 2021, in English, Portuguese and Spanish, in the databases of the Regional Portal of the Virtual Health Library, in MEDLINE through PubMed and in Capes Journal Portal used: Embase, Scopus, Web of Science, CINAHL. The texts were imported into EndNote, duplicates were removed and exported to the Rayyan application, and the articles were included in an Excel spreadsheet with the labels: COVID-19 as injuries at work and Notification of COVID-19. Results A total of 5665 studies were identified, excluding 2088 duplicates, resulting in 3577 publications, selected by title and abstract. Of these, 3280 did not meet the inclusion criteria, resulting in 297 articles. Of these, 10 were selected for full text analysis because they dealt with COVID-19 as an injury at work and/or notification of this condition by health workers. Two articles were excluded because they were a literature review, remaining 8 as the study’s corpus. Conclusion Although certain countries already recognize COVID-19 as an occupational injury, some workers still have difficulties in relating the SARS-CoV-2 infection with work in health care, characterizing it as an occupational injured. Everyone should be guided and trained regarding the recognition of COVID-19 as an occupational injury and notify its occurrence, since the definition of the infection as a notifiable disease already exists. COVID19 COVID 19 COVID-1 202 2021 English Spanish Library used Embase Scopus Science CINAHL EndNote application labels COVID19. 19. 566 identified 208 357 abstract these 328 criteria 29 1 andor or studys study s corpus SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- care injured occurrence exists COVID1 COVID- 20 56 35 32 SARS-CoV 5 3

Abstract The purpose of this study was to evaluate the effect of dentin moisture (moist and dry) on the bonding of fiber posts to root dentin with different adhesive strategies (etch-and-rinse, self-etch, and self-adhesive). Seventy-two extracted single-rooted human teeth were endodontically treated and divided into six groups (n = 12) according to the moisture of dentin surface and adhesive systems as follows: a) etch-and-rinse/moist, b) etch-and-rinse/dry, c) self-etch/moist, d) self-etch/dry, e) self-adhesive/moist, and 6) self-adhesive/dry. The specimens were sectioned into six slices for push-out bond strength (BS), nanoleakage (NL) by SEM, and Vickers microhardness (VHN) of the resin cement. A universal testing machine (AG-I, Shimadzu Autograph) was used at a crosshead speed of 0.5 mm/min until post extrusion, with a load cell of 50 kg for evaluation of the push-out strength. Data on BS, NL, and VHN were evaluated by two-way ANOVA and Tukey’s test (α = 0.05). Dentin moisture as the main factor was not significantly different for the push-out test. However, higher BS values can be observed for the etch-and-rinse group. A lower percentage of NL was found in the dry dentin groups. The moisture pattern was not significant in the hardness values for the pre-etching groups. Additional moisture did not increase the evaluated properties. moist etchandrinse, etchandrinse etch rinse, rinse (etch-and-rinse selfetch, selfetch self etch, self-etch selfadhesive. selfadhesive . self-adhesive) Seventytwo Seventy two singlerooted single rooted n 12 follows etchandrinse/moist, etchandrinsemoist rinse/moist, etch-and-rinse/moist b etchandrinse/dry, etchandrinsedry rinse/dry, etch-and-rinse/dry c selfetch/moist, selfetchmoist etch/moist, self-etch/moist d selfetch/dry, selfetchdry etch/dry, self-etch/dry e selfadhesive/moist, selfadhesivemoist adhesive/moist, self-adhesive/moist 6 selfadhesive/dry. selfadhesivedry adhesive/dry. self-adhesive/dry pushout push out , (BS) (NL SEM (VHN cement AGI, AGI AG I, I (AG-I Autograph 05 0 5 0. mmmin mm min extrusion twoway way Tukeys Tukey s α 0.05. 005 0.05 0.05) However group preetching pre etching properties self-adhesive 1 etchandrinse/moist rinsemoist rinse/moist etchandrinse/dry rinsedry rinse/dry selfetch/moist etchmoist etch/moist selfetch/dry etchdry etch/dry selfadhesive/moist adhesivemoist adhesive/moist selfadhesive/dry adhesivedry adhesive/dry (BS 00 0.0

Abstract Despite the availability of in-office bleaching gels with a 6% concentration of hydrogen peroxide (HP), these gels have not been evaluated in younger patients. They are commercially available with a tip, associated or not with a brush, where the tip with a brush spreads the gel over the entire surface to have a smaller thickness (thin layer) since the manufacturers indicate the application of a thin layer of gel. Objective This randomized, split-mouth, double-blind clinical trial evaluated the efficacy of in-office bleaching with 6% HP in adolescents using different application tips, as well tooth sensitivity (TS) and aesthetic self-perception. Methodology Sixty participants were randomized for 6% HP self-mixing bleaching gel tip design: without brush and with brush. In-office bleaching was performed in 3 sessions of 50 minutes. Color change was evaluated using a digital spectrophotometer (ΔE ab , ΔE 00 , and ΔWI D ) and color guide (ΔSGU), the absolute risk and intensity of TS with a visual analogue scale and aesthetic self-perception with the oral aesthetic scale (a=0.05). Results The groups achieved similar bleaching regardless of the application tip (p>0.05). However, only for ΔWI D , a significant mean difference (MD) was observed in the third week (MD 2.3; 95% CI 1.2 to 3.3; p < 0.001) and at one month (MD 1.6; 95% CI 0.6 to 2.6; p < 0.03) favoring the tip without brush. Regarding TS, 45% in the tip-without-brush group and 33% in the tip-with-brush group reported TS (odds ratio 0.61; 95% CI 0.29 to 1.28; p<0.02), with low TS intensity (MD 0.05; 95% CI -0.06 to 0.17; p>0.36). All patients reported improved aesthetic self-perception after bleaching (MD -1.3; 95% -1.8 to -0.9; p<0.001). Conclusions Regardless of the tip used bleaching with 6% HP achieved a bleaching efficacy and improved the aesthetic self-perception. However, a lower risk of TS for application using the tip with brush was observed. inoffice office 6 HP, (HP) splitmouth, splitmouth split mouth, mouth split-mouth doubleblind double blind tips (TS selfperception. selfperception self perception. perception selfmixing mixing design Inoffice In 5 minutes 0 ΔSGU, ΔSGU (ΔSGU) a=0.05. a005 a=0.05 . 05 (a=0.05) p>0.05. p005 p>0.05 (p>0.05) However MD 2.3 23 2 95 12 1 1. 3.3 33 0.001 0001 001 1.6 16 06 0. 2.6 26 0.03 003 03 45 tipwithoutbrush tipwithbrush odds 0.61 061 61 029 29 0.2 1.28 128 28 p<0.02, p002 p<0.02 02 p<0.02) 0.05 005 0.06 006 -0.0 0.17 017 17 p>0.36. p036 p>0.36 36 p>0.36) 1.3 13 -1.3 1.8 18 8 -1. 0.9 09 9 -0.9 p<0.001. p0001 p<0.001 p<0.001) (HP (ΔSGU a00 a=0.0 (a=0.05 p00 p>0.0 (p>0.05 2. 3. 0.00 000 0.0 4 p<0.0 -0. 0.1 01 p03 p>0.3 -1 p000 p<0.00 a0 a=0. (a=0.0 p0 p>0. (p>0.0 p<0. -0 - a=0 (a=0. p>0 (p>0. p<0 a= (a=0 p> (p>0 p< (a= (p> (a (p

Abstract: Appropriate research reports are important to facilitate the evaluation of studies and the decision-making by dentists and policymakers. This meta-research study assessed the conformity of randomized clinical trials (RCTs) on atraumatic restorative treatment (ART) restorations with the CONSORT recommendations and their risk of bias (RoB). Cochrane Library, MEDLINE, BBO, LILACS, Scopus, and Web of Science databases were searched from April 2019 to June 2021 for RCTs that assessed the longevity of ART restorations in children. A specific tool was used to assess adherence to the CONSORT recommendations; RoB was evaluated with the Cochrane risk-of-bias tool. Descriptive analyses included the number of studies by journal, follow-up period, country, and quality assessments. A total of 2,181 papers were retrieved and 36 of them were analyzed qualitatively. The overall CONSORT mean score (CONms) was 22.52 ± 6.17 out of 32 points. The best described items were intervention and outcomes, whereas allocation concealment was described in only 22% of the papers. Significant differences in CONms were detected in the analysis by country and publication dates. High CONms were observed in recently published papers (26.7 ± 3.1) when compared to first ART studies (18.1 ± 4.6; p < 0.001). RoB was low in four studies, unclear in 11, and high in 21. Adherence of the papers to the CONSORT recommendations was not fully achieved and most of the papers had unclear and high RoB (PROSPERO registration #CRD42020201460).

Resumo Este estudo investigou o efeito do dimetil sulfóxido combinado a agentes de reticulação de colágeno na resistência de união à microtração, infiltração de nitrato de prata e análise do grau de conversão por Micro-Raman de sistemas adesivos universais para a dentina erosionada por refrigerante a base de Cola. Cento e sessenta molares foram divididos em 20 grupos: (1) Tratamento: Dentina sadia; Dentina erosionada; Dentina erosionada tratada com primer de dimetil sulfóxido; Dentina erosionada tratada com primer contendo 6,5% de proantocianidina e; Dentina erosionada tratada com primer contendo 0,1% de rivoflavina; (2) Sistemas adesivos: iBond Universal e Scotchbond Universal; e (3) estratégia adesiva: estratégia condicionamento e lavagem ou autocondicionate. Após a restauração, os espécimes foram seccionados em palitos e testados. Os dados dos três testes foram analisados estatisticamente (ANOVA de 2 e 3 fatores e teste de Tukey; α = 5%). A aplicação de dimetil sulfóxido combinado ou não agentes de reticulação de colágeno melhorou todas as propriedades avaliadas quando comparado a dentina erosionada. Entretanto, apenas quando o dimetil sulfóxido foi combinado com agentes de reticulação de colágeno, os valores de adesão a dentina, infiltração de nitrato de prata e grau de conversão em dentina erosionada foi semelhante a dentina sadia, para os dois adesivos e estratégias adesivas. A aplicação de dimetil sulfóxido combinado com agentes de reticulação de colágeno contribuiu para aumentar a resistência de união e o grau de conversão dentro da camada híbrida na dentina erodida, ao mesmo tempo que reduziu significativamente a nanoinfiltração neste substrato.

Abstract To investigate the effect of the dimethyl sulfoxide combined with cross-linking agents on microtensile bond strength, silver nitrate penetration and in situ degree of conversion analysis of adhesives to the erosive dentin treatment with Cola-based soft drink. One hundred and sixty-six molars were assigned to 20 groups: (1) Treatment: Sound dentin; Erosive dentin; Erosive dentin treated with primer of dimethyl sulfoxide; Erosive dentin treated with DMSO primer containing proanthocyanidin and rivoflavin; (2) Adhesive systems: iBond Universal and Scotchbond Universal; and (3) adhesive strategy: etch-and-rinse or self-etch strategy. After restoration, specimens were sectioned into sticks to be tested. The data from microtensile bond strength (MPa), silver nitrate penetration (%) and in situ degree of conversion (%) were analyzed by (three- and two-factor ANOVA; Tukey's test α=5%). The application of dimethyl sulfoxide combined of not with cross-linkers improved all properties evaluated when compared to only erosive dentin treatment with Cola-based soft drink. However, only when dimethyl sulfoxide was combined to cross-linkers, the values of the microtensile bond strength, silver nitrate penetration and in situ degree of conversion in erosive dentin treatment with Cola-based soft drink was similar to sound dentin, for both adhesives and adhesive strategies. The application of dimethyl sulfoxide combined with the collagen cross-linking agent contributed to increasing the bond strength and degree of conversion in erosive lesion dentin, at the same time that significantly reduction of nanoleakage in this substrate.

Resumo Este ensaio clínico avaliou o efeito da coadministração de ibuprofeno/cafeína na sensibilidade dental decorrente de clareamento (SD). Um estudo clínico randomizado, paralelo, triplo-cego, foi realizado em 84 pacientes que receberam cápsulas de ibuprofeno/cafeína ou placebo. Os fármacos foram administrados por 48 horas, começando 1 hora antes do clareamento em consultório. Duas sessões de clareamento foram realizadas com gel de peróxido de hidrogênio 35% com intervalo de 1 semana. A SD foi registrada até 48 horas após o clareamento dental com uma escala visual analógica (VAS) de 0-10 e uma escala de classificação numérica (NRS) de 5 pontos. A cor foi avaliada com as escalas Vita Classical e Vita Bleachedguide (ΔSGU) e com o espectrômetro Vita Easyshade (ΔE*ab e ΔE00). O risco absoluto de SD em ambos os grupos foi avaliado por meio do teste exato de Fischer. As comparações da intensidade da SD (NRS e VAS) foram realizadas utilizando-se o teste Mann-Whitney e uma ANOVA de dois fatores com medidas repetidas, respectivamente. A alteração de cor entre os grupos foi comparada com a o teste t de Student. O nível de significância foi de 5%. Não houve diferença estatisticamente significante entre os grupos para o risco absoluto de SD (p = 1,00) ou para a intensidade de SD (p > 0,05). Observou-se clareamento de aproximadamente 7 unidades nas escalas Vita Classical e Vita Bleachedguide, sem diferença estatística entre os grupos. Concluiu-se que a coadministração de ibuprofeno e cafeína não reduziu o risco absoluto ou intensidade da SD e não interferiu na eficácia do clareamento dental.

Abstract This clinical trial evaluated the effect of the coadministration of ibuprofen/caffeine on bleaching-induced tooth sensitivity (TS). A triple-blind, parallel-design, randomized clinical trial was conducted on 84 patients who received ibuprofen/caffeine or placebo capsules. The drugs were administered for 48 hours, starting 1 hour before the in-office bleaching. Two bleaching sessions were performed with 35% hydrogen peroxide gel with 1-week interval. TS was recorded up to 48 hours after dental bleaching with a 0-10 visual analogic scale (VAS) and a 5-point numeric rating scale (NRS). The color was evaluated with VITA Classical and VITA Bleachedguide scales (ΔSGU) and VITA Easyshade spectrophotometer (ΔE*ab and ΔE00). The absolute risk of TS in both groups was evaluated using Fischer's exact test. Comparisons of the TS intensity (NRS and VAS data) were performed by using the Mann-Whitney test and a two-way repeated measures ANOVA, respectively. The color alteration between the groups was compared with the Student's t test. The significance level was 5%. There was no statistically significant difference between the groups for the absolute risk of TS (p = 1.00) or for the intensity of TS (p > 0.05). A bleaching of approximately 7 shade guide units was observed on the Vita Classical and Vita Bleachedguide scales, with no statistical difference between the groups. It was concluded that coadministration of ibuprofen and caffeine did not reduce the absolute risk or intensity of TS and did not interfere with the efficacy of dental bleaching.

Abstract The purpose of this study was to analyze the effect of the application of different concentrations of EDTA on the adhesion of fiber posts to root dentin using self-adhesive resin cements. After endodontic treatment, 78 single roots were randomly divided into six groups (n = 13) according to the combination of the following factors: surface dentin treatment – control (distilled water), 17% EDTA and 24% EDTA; and self-adhesive resin cement - RelyX U200 (RX); and Multilink Speed (ML). After fiber post cementation, six slices were obtained for each root. Ten roots of each group were used for bond strength (BS) and three for microhardness (MH) evaluations. Data obtained from BS and MH tests for each resin cement were subjected to two-way ANOVA (surface treatment vs. root region) and to a post-hoc Tukey’s test (α = 0.05). The lowest BS value was observed in the 24% EDTA group for RX cement, whereas the highest values for ML cement were observed for the control group in the middle and apical regions. In the MH test, the lowest value for RX was observed for 24% EDTA in the cervical region, whereas and the highest value for the ML cement was observed in the control group. Regarding both self-adhesive resin cements tested, the application of 24% EDTA was not able to improve the adhesion of fiber posts to root canal.

RESUMO As narrativas de educadores da saúde configuram-se como dispositivo que favorece a compreensão de aprendizagens experienciais no espaço formativo da Pós-Graduação em Educação na Saúde. Seu contexto de inserção são as Residências em Saúde, espaços de formação que integram o ensino e os serviços do Sistema Único de Saúde (SUS) no Brasil. Ancorados em princípios da pesquisa (auto)biográfica e na utilização de memoriais, objetiva-se discutir questões relacionadas ao processo de acompanhamento, suas interfaces com as escritas de si e as disposições de investigação-formação mobilizadas pela escrita de memoriais de três educadores no campo da formação em saúde, na condição de preceptores no Programa de Residências da Fundação Estatal Saúde da Família (FESF-SUS) na Bahia. As experiências de cuidado e de educação em equipes multiprofissionais são colocadas em reflexão nos memoriais de formação de educadores da saúde como processo de mediação do vivido e das relações entre formador e formandos, por meio das narrativas de experiências, com ênfase no desenvolvimento pessoal e profissional no contexto da formação em saúde.

ABSTRACT The narratives of health educators are configured as a device that favors the understanding of experiential learning in the formative space of graduate studies in Health Education. Its context of insertion is Health Residencies, training spaces that integrate the teaching and services of the Unified Health System (known as SUS) in Brazil. Based on principles of the (auto)biographical research and in the use of memorials, the objective is to discuss issues related to the monitoring process, its interfaces with the writing about oneself, and the investigation-training provisions mobilized by writing the memorials of three educators in the field of Health Education, as preceptors in the Residency Program of the State Foundation for Family Health (Fundação Estatal Saúde da Família - FESF-SUS) in Bahia. The experiences of care and education in multi-professional teams are reflected in memorials for the training of health educators, as a process of mediation of what was experienced, and of the relationships between trainer and trainees, through the narratives of experiences with an emphasis on personal and professional development in the context of Health training.

RESUMO: O conhecimento das alterações fisiológicas que ocorrem quando os animais são submetidos a alterações climatológicas consideradas estressantes é fundamental para manter o bem-estar animal, e poder explorar o seu potencial reprodutivo de forma eficiente e racional. O presente estudo foi realizado com o objetivo de avaliar a influência de variáveis climáticas sobre parâmetros fisiológicos e de ejaculados de búfalos, da raça Murrah, criados em clima tropical úmido da Amazônia. As análises imediatas pertinentes às características físicas e morfológicas dos ejaculados foram realizadas e corresponderam no período chuvoso (PCh) o volume de 3,4±2,0mL, turbilhonamento de 4,4±0,5; motilidade de 80,4±5,6%; vigor de 4,4±0,4; concentração de 657.300±237.865,1 x 106sptz/mL; defeitos maiores de 9,0±2,6%; defeitos menores de 11,2±3,9%; defeitos totais de 20,2±5,3% e integridade da membrana plasmática (IMP) de 84,8±5,6%, enquanto que no período não chuvoso (PnCh), os resultados foram de 4,0±2,1mL; turbilhonamento de 3,0±1,0; motilidade de 56,2±13,4%; vigor de 3,0±1,0; concentração de 586.000±291.925,9 x 106sptz/mL; defeitos maiores de 20,8±9,9%; defeitos menores de 27,5±6,3%; defeitos totais de 48,3±9,3% e IMP de 57,9±12,4%. Observou-se diferença estatística (P<0,05) para os parâmetros movimento de massa, motilidade, vigor, defeitos maiores, defeitos menores, defeitos totais e integridade da membrana plasmática entre os dois períodos. Dados de frequência cardíaca, temperatura superficial (cabeça, dorso, virilha e bolsa escrotal) diferiram estatisticamente entre os períodos (P<0,05). Conclui-se que se faz necessário usar de um manejo específico no período não chuvoso para que o estresse térmico não seja um fator determinante na redução da qualidade reprodutiva dos búfalos, para isto se faz necessário utilizar de meios para melhorar o bem-estar animal, sendo uma das alternativas fazer uso de banhos regularmente para estes animais, ou disponibilizar acesso constante destes a áreas de rios ou lagos, assim como sombreamentos, evitando que os búfalos fiquem expostos diretamente ao ambiente térmico desfavorável.

ABSTRACT: Awareness of the physiological changes that occur when animals are subjected to climatic changes that are considered stressful is essential to maintain animal welfare and to be able to exploit their reproductive potential efficiently and rationally. The present study was carried out to evaluate climatic variables’ influence on physiological parameters, and Murrah buffalo ejaculates reared in a humid tropical climate in the Amazon. The immediate analyzes pertinent to the physical and morphological characteristics of the ejaculates were carried out and corresponded in the rainy season (RS) volume of 3.4±2.0mL; the mass activity of 4.4±0.5; motility of 80.4±5.6%; vigor of 4.4±0.4; concentration of 657,300±237,865.1 x 106sptz/mL; major defects of 9.0±2.6%; minor defects of 11.2±3.9%; total defects 20.2±5.3% and sperm plasma membrane integrity (SPMI) 84.8±5.6%, whereas in the non-rainy season (nRS), the results were 4.0±2.1mL; the mass activity of 3.0±1.0; motility of 56.2±13.4%; vigor of 3.0±1.0; concentration of 586,000±291,925.9 x 106sptz/mL; major defects of 20.8±9.9%; minor defects of 27.5±6.3%; total defects 48.3±9.3% and SPMI of 57.9±12.4%. Furthermore, a statistical difference (P<0.05) was observed for the parameters mass activity, motility, vigor, major defects, minor defects, total defects, and sperm plasma membrane integrity between both periods. The data on heart frequency, superficial temperature (head, back, groin, and scrotal pouch) showed a statistical difference between both periods (P<0.05). To conclude is necessary specific management in the non-rainy season that thermal stress is not a determining factor in reducing the reproductive quality of buffaloes; it is necessary to use means to improve animal welfare; one alternative is to use baths regularly for these animals or provide constant access to areas of rivers or lakes, as well as shading, preventing the buffaloes from being directly exposed to the unfavorable thermal environment.

Resumo Este estudo teve como objetivo quantificar a permeabilidade do peróxido de hidrogênio (PH), avaliação da mudança de cor, morfologia da superfície e composição de elementos após a aplicação de agentes dessensibilizantes antes do clareamento em consultório. Cinquenta pré-molares foram seccionados, um tampão de acetato foi colocado na câmara pulpar e divididos em cinco grupos (n=10). No grupo controle positivo, apenas o gel clareador em consultório foi utilizado e no grupo controle negativo nenhum tratamento foi realizado. Foram aplicados três agentes dessensibilizantes diferentes: grupo KF2%®; grupo Mi Paste® e Desensibilize Nano-P®. O procedimento de clareamento foi realizado com PH a 35%. A absorbância da solução resultante foi determinada em um espectrofotômetro. A mudança de cor foi avaliada utilizando um espectrofotômetro digital. Quatro pré-molares adicionais foram atribuídos aos mesmos grupos acima para análise em microscópio eletrônico de varredura, bem como para avaliar a composição elementar com espectrometria de energia dispersiva por raios-X. Os dados foram submetidos ao teste ANOVA e Tukey (a=0,05). Todos os produtos reduziram a penetração de PH na câmara pulpar. Mi Paste e Nano P foram os produtos que apresentaram a menor penetração de PH, semelhante ao grupo controle negativo (p<0,001). Nenhuma diferença significativa foi detectada na mudança de cor (p<0,001). Em relação à morfologia do esmalte, os grupos analisados após o clareamento apresentou maior deposição de agentes dessensibilizantes na superfície. O uso de agentes dessensibilizantes antes do clareamento dental parece ser uma alternativa para reduzir os efeitos adversos no dente.

Abstract This study aimed to quantify the penetration of hydrogen peroxide, color change evaluation, surface morphology, and composition after application of desensitizing agents before in-office bleaching. Fifty premolars were sectioned, an acetate buffer was placed in the pulp chamber and divided into five groups (n=10). In the positive control group, only the in-office bleaching gel was used, and in the negative control group, no treatment was used. Three different desensitizing agents were applied: Desensibilize KF2%® group; Mi Paste® group, and Desensibilize Nano-P® group. The bleaching procedure was carried out with 35% HP. The absorbance of the resulting solution was determined in a spectrophotometer. Color change was assessed by using a digital spectrophotometer. Four additional premolars were assigned to the same groups above for analysis under scanning electron microscope, as well as to evaluate the elemental composition with X-ray dispersive energy spectrometry. Data were subjected to ANOVA and Tukey's test (α=0.05). All products reduced the penetration of HP in the pulp chamber. Mi Paste and Nano P were the products that yielded the lowest HP penetration, which was similar to the negative control group (p<0.001). No significant difference was detected in color change (p<0.001). Concerning enamel morphology, the groups that were analyzed after bleaching were observed a greater deposition of desensitizing agents on the surface. The use of desensitizing agents before tooth bleaching seems to be an alternative to reduce adverse effects of the tooth.