Metallic materials are generally characterized by the evaluation of hardness and wear resistance of the material at the specified condition. The characterization is necessary for understanding the behavior of the metals, especially alloys, at different conditions. To study the effect of heat treatment on weld deposited Co-Cr-Mo alloy, arc welding process has been used to prepare the samples.Using L9 Orthogonal array of Taguchi method, the samples, in three groups,are heat treated by solution at 1200ºC for 30, 45 and 60minutes followed by water quenching. Two sets of the samples from each groupare aged at 815ºC and 830ºC for 2, 4 and 6 hours. All the samples are then tested for their hardness andwear resistances. Microstructure analysis has been carried out from SEM images of the samples. The experiment results reveal that the differences in heat treatment did not influence the grain size of the samples, but the precipitation of carbides varies from sample to sample. The Co-Cr-Mo alloy samples solutionized at 1200ºC for 60minutes have exhibited high hardness (371.6±2Hv) and wear resistances. For high hardness and wear resistance, high solution time is required. ANOVA has been carried out to identify the best parameters of heat treatment.