Resumen Este estudio tuvo como objetivo describir el primer curso presencial para capacitar a los profesionales de la salud pública para llevar a cabo la vigilancia genómica en tiempo real durante los períodos de pandemia. Este es un informe de experiencia en un curso teórico-práctico centrado en la investigación y vigilancia genómica, que incluye secuenciación móvil, bioinformática, filogenética y tecnologías de modelado epidemiológico. Este evento contó con la asistencia de 162 participantes y fue la primera gran capacitación presencial realizada durante la epidemia de COVID-19 en Brasil. No se detectó infección por SARS-CoV-2 al final del evento en ningún participante, lo que sugiere la seguridad y efectividad de todas las medidas de seguridad adoptadas. Por lo tanto, los resultados del evento sugieren que es posible realizar entrenamientos profesionales de manera segura durante pandemias, siempre y cuando se sigan todos los protocolos de seguridad. pandemia teóricopráctico teórico práctico móvil bioinformática epidemiológico 16 COVID19 COVID 19 COVID-1 Brasil SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- participante adoptadas tanto pandemias 1 COVID1 COVID- SARS-CoV

Abstract The objective of this report was to describe the first face-to-face course aimed at training public health professionals in performing real-time genomic surveillance during the pandemic period. Experience report on a theoretical-practical course focusing on genomic research and surveillance, including mobile sequencing technologies, bioinformatics, phylogenetics and epidemiological modeling. There were 162 participants in the event and it was the first major face-to-face training course conducted during the COVID-19 epidemic in Brazil. No cases of SARS-CoV-2 infection was detected among the participants at the end of the event, suggesting the safety and effectiveness of all safety measures adopted. The results of this experience suggest that it is possible to conduct professional training safely during pandemics, as long as all safety protocols are followed. facetoface face realtime real time period theoreticalpractical theoretical practical technologies bioinformatics modeling 16 COVID19 COVID 19 COVID-1 Brazil SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- adopted pandemics followed 1 COVID1 COVID- SARS-CoV

Resumo O relato descrebeu o primeiro curso presencial visando capacitar profissionais de saúde pública na realização de vigilância genômica em tempo real, durante períodos pandêmicos. Relato de experiência sobre um curso teórico-prático com foco em pesquisa e vigilância genômica, incluindo tecnologias de sequenciamento móvel, bioinformática, filogenética e modelagem epidemiológica. O evento contou com 162 participantes e foi o primeiro grande treinamento presencial realizado durante a epidemia de covid-19 no Brasil. Não foi detectada infecção pelo SARS-CoV-2 ao final do evento em nenhum participante, sugerindo a segurança e efetividade de todas as medidas de segurança adotadas. Os resultados do evento sugerem que é possível executar capacitação profissional com segurança durante pandemias, desde que seguidos todos os protocolos de segurança. real pandêmicos teóricoprático teórico prático móvel bioinformática epidemiológica 16 covid19 covid 19 covid-1 Brasil SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- participante adotadas pandemias 1 covid1 covid- SARS-CoV

Resumo O relato descrebeu o primeiro curso presencial visando capacitar profissionais de saúde pública na realização de vigilância genômica em tempo real, durante períodos pandêmicos. Relato de experiência sobre um curso teórico-prático com foco em pesquisa e vigilância genômica, incluindo tecnologias de sequenciamento móvel, bioinformática, filogenética e modelagem epidemiológica. O evento contou com 162 participantes e foi o primeiro grande treinamento presencial realizado durante a epidemia de covid-19 no Brasil. Não foi detectada infecção pelo SARS-CoV-2 ao final do evento em nenhum participante, sugerindo a segurança e efetividade de todas as medidas de segurança adotadas. Os resultados do evento sugerem que é possível executar capacitação profissional com segurança durante pandemias, desde que seguidos todos os protocolos de segurança.

Resumen Este estudio tuvo como objetivo describir el primer curso presencial para capacitar a los profesionales de la salud pública para llevar a cabo la vigilancia genómica en tiempo real durante los períodos de pandemia. Este es un informe de experiencia en un curso teórico-práctico centrado en la investigación y vigilancia genómica, que incluye secuenciación móvil, bioinformática, filogenética y tecnologías de modelado epidemiológico. Este evento contó con la asistencia de 162 participantes y fue la primera gran capacitación presencial realizada durante la epidemia de COVID-19 en Brasil. No se detectó infección por SARS-CoV-2 al final del evento en ningún participante, lo que sugiere la seguridad y efectividad de todas las medidas de seguridad adoptadas. Por lo tanto, los resultados del evento sugieren que es posible realizar entrenamientos profesionales de manera segura durante pandemias, siempre y cuando se sigan todos los protocolos de seguridad.

Abstract The objective of this report was to describe the first face-to-face course aimed at training public health professionals in performing real-time genomic surveillance during the pandemic period. Experience report on a theoretical-practical course focusing on genomic research and surveillance, including mobile sequencing technologies, bioinformatics, phylogenetics and epidemiological modeling. There were 162 participants in the event and it was the first major face-to-face training course conducted during the COVID-19 epidemic in Brazil. No cases of SARS-CoV-2 infection was detected among the participants at the end of the event, suggesting the safety and effectiveness of all safety measures adopted. The results of this experience suggest that it is possible to conduct professional training safely during pandemics, as long as all safety protocols are followed.

Abstract Since the emergence of the chikungunya virus in Brazil in 2014, more than 700,000 cases have been reported throughout the country, corresponding to one-third of all cases reported in the Americas. In addition to its high attack rates, resulting in hundreds of thousands of cases, the disease has high chronicity rates with persistent joint manifestations for more than 3 months, which can spread to more than half of the patients affected in the acute phase. Pain associated with musculoskeletal manifestations, often disabling, has an effect on patients’ quality of life at different stages of the disease. Currently, the challenge faced by specialists is identifying the best therapy to be instituted for symptom relief despite the limited number of published intervention studies. In 2016, a multidisciplinary group published pharmacological treatment protocols for pain in patients with chikungunya, which was incorporated into the guidelines for clinical management of the Brazilian Ministry of Health in 2017; in that same year, a consensus was published by the Brazilian Society of Rheumatology about diagnosis and treatment. After 5 years of experience with chikungunya epidemics, in 2019, specialists involved in the protocols of the Brazilian Society of Rheumatology and Brazilian Ministry of Health prepared an update with the main objective of developing flowcharts for the therapeutic approach of musculoskeletal manifestations in adult patients to enable specialists at different levels of healthcare to spread and apply this guideline in a systematic and simplified manner.

Abstract INTRODUCTION: Since 2016, Brazil has been in the midst of its largest sylvatic yellow fever epidemic ever, found predominantly outside the Amazon region. Cases originating from Brazil have been reported in France, the Netherlands, Romania, Switzerland, Argentina, and Chile. The epidemic began in the Central-West region of Brazil in 2014, spreading into the Southern region, with significant non-human primate transmission continuing towards Paraguay and Argentina. METHODS: This report is an integrative review of Pan American Health Organization cooperation during a sylvatic yellow fever epidemic. RESULTS: The Pan American Health Organization has played a central role in handling the yellow fever emergency, collaborating with the Ministry of Health and various research groups in supporting interventions of different response areas. The Pan American Health Organization's technical cooperation included: training and workshops to exchange experiences, carrying out technical cooperation in patient management and epidemiological, entomological, laboratory, and epizootic surveillance, organizing the assistance network, and acquiring strategic inputs. The Pan American Health Organization’s technical cooperation supported the Ministry of Health’s decision to adopt a single-dose vaccine and use fractional doses to support the vaccination needs of more than 39,000,000 people. The coronavirus disease 2019 pandemic contributed to the failure of reaching the yellow fever vaccination goals and made it difficult to integrate the yellow fever vaccine into recommended areas. CONCLUSIONS: Given the ongoing coronavirus disease 2019 pandemic, it is necessary to strengthen measures for the surveillance, prevention, and control of yellow fever with multilateral cooperation between countries.

Los Equipos de Protección Personal (EPP) son utilizados en la salud pública para proteger a los trabajadores que manejan plaguicidas para el control de vectores de enfermedades. La exposición cutánea es el mayor riesgo de contaminación. La permeabilidad de los EPP es una característica que hace su uso inadecuado. Incluso los EPP hechos de materiales impermeables pueden ser permeables debido a la porosidad de la tela y a las costuras. Esta investigación analizó la permeabilidad de los EPP a los plaguicidas utilizados para combatir el mosquito Aedes Aegypti. La permeabilidad se evaluó por el método de la pipeta, computando el porcentaje de repelencia, retención y penetración de los plaguicidas en los EPP. Los resultados mostraron que el tipo de costura influye en la permeabilidad y que una repelencia inferior puede no ser suficiente para evaluar la eficiencia de un EPP, ya que puede ser compensada por una mayor retención, lo que resulta en menos penetración.

Os Equipamentos de Proteção Individuais (EPI) são utilizados na Saúde Pública para proteger os trabalhadores que utilizam agrotóxicos para controle de vetores de doenças. A exposição dérmica representa o maior risco de contaminação. A permeabilidade é uma característica que torna os EPI inadequados ao uso. Mesmo os EPI confeccionados com materiais impermeáveis, podem ser permeáveis, devido à porosidade dos tecidos e as costuras. Este estudo analisou a permeabilidade dos EPI aos agrotóxicos utilizados no combate ao mosquito Aedes Aegypti. A permeabilidade foi avaliada através do método da pipeta, calculando-se as porcentagens de repelência, de retenção e de penetração dos agrotóxicos nos EPI. Os resultados mostraram que: o tipo de costura influencia na permeabilidade; e que uma menor repelência pode não ser suficiente para avaliar a eficiência de um EPI, pois esta pode ser compensada por uma maior retenção, resultando em uma menor penetração.

Les équipements de protection individuelle (EPI) sont utilisés en santé publique pour protéger les travailleurs qui utilisent des pesticides pour lutter contre certaines maladies. L'exposition cutanée représente le plus grand risque de contamination. La perméabilité est une caractéristique des EPI qui les rend impropres à une utilisation. Même les EPI fabriqués à partir de matériaux imperméables sont perméables en raison de la porosité du tissu et des coutures. Cette étude a analysé la perméabilité des EPI contre les pesticides utilisés pour lutter contre les moustiques Aedes aegypti. La perméabilité a été évaluée par la méthode de la pipette, en calculant les pourcentages de répulsion, de rétention et de pénétration des pesticides dans l'EPI. Les résultats ont montré : que le type de couture influence la perméabilité; et qu'une répulsivité inférieure peut ne pas être suffisante pour évaluer l'efficacité de l'EPI, puisque celle-ci peut être compensée par une plus grande rétention, ce qui entraîne moins de pénétration.

Personal Protective Equipment (PPE) is used in Public Health to protect the workers who use pesticides for disease control. The dermal exposure is the highest contamination risk. The permeability is a characteristic that makes PPE unsuitable for using. Even those PPE which are made from waterproof materials, can be permeable, due to fabric porosity and the presence of seams. This study analysed the permeability to pesticides on PPE used by health personnel controlling Aedes aegypti mosquito. Permeability was evaluated through the pipette method, by calculating repellency, retention and penetration percentages of pesticides in the PPE. The results showed that the type of seam influences permeability; and a lower repellency may not be sufficient to evaluate the efficiency of PPE, as this can be compensated by a greater retention, resulting in less penetration.