Generalized anxiety disorder is a highly prevalent mental disorder. Previous data indicate that more than 18 million Brazilians suffer from this condition. Traditionally, generalized anxiety disorder has been considered a mild mental health disorder, despite its links to lower life expectancy, cardiovascular disease, and suicide. The aim of this article is to combine elements of systematic and critical reviews to produce a synthesis of the best evidence about generalized anxiety disorder treatment. Systematic reviews, meta-analyses, and randomized controlled trials were included. The descriptor used in the search was “generalized anxiety disorder,” which resulted in 4,860 articles and seven other studies, of which 59 were selected. Antidepressants and benzodiazepines were indicated, as was pregabalin, and atypical antipsychotics, such as quetiapine, have been studied. Individual cognitive behavior therapy (third wave) has proven effective. There is extensive literature on many effective treatments for generalized anxiety disorder. The present review summarizes the therapeutic possibilities, emphasizing those available in Brazil. Further studies are needed to compare other available medications, assess psychotherapies and new treatments in greater depth, as well as to assess the ideal duration of therapy. Registration number: PROSPERO CRD42021288323. 1 condition Traditionally expectancy disease suicide treatment metaanalyses, metaanalyses meta analyses, analyses meta-analyses included 4860 4 860 4,86 5 selected indicated pregabalin antipsychotics quetiapine studied third wave possibilities Brazil medications depth number CRD42021288323 CRD 486 86 4,8 CRD4202128832 48 8 4, CRD420212883 CRD42021288 CRD4202128 CRD420212 CRD42021 CRD4202 CRD420 CRD42 CRD4

Abstract Objective: To translate and validate the version for children and adolescents of the UPPS-P scale into Brazilian Portuguese. Method: After a five-step translation process, the final draft was submitted to a panel of 12 different specialties experts. Subsequently, the application of the scale was applied concomitantly with the "Swanson, Nolan, and Pelham Scale - Version IV" (SNAP-IV) and the "Child and Adolescent Behavior Inventory" (CABI) scale to analyze the correlation between them. Content Validity Index (CVI) and reliability were estimated by calculating internal consistency and analyzing its test-retest stability. Results: The items whose CVI was lower than 80% underwent a detailed analysis to verify the reason for the bad evaluation. Five items (3, 7, 11, 22 and 35) scored below 80% and were reassessed. There was high internal consistency in all parameters: Lack of premeditation (McDonald's omega = 0.806; Cronbach's alpha = 0.801), Negative Urgency (McDonald's omega = 0.838; Cronbach's alpha = 0.836), Sensation seeking (McDonald's omega = 0.826; Cronbach's alpha = 0.810), Lack of Perseverance (McDonald's omega = 0.800; Cronbach's alpha = 0.799) and Positive Urgency (McDonald's omega = 0.936; Cronbach's alpha = 0.934). A strong correlation was observed between UPPS-P features and impulsivity in behavioral assessments. Conclusions: The Brazilian Portuguese version of the UPPS-P scale is a good instrument to assess impulsivity in children and adolescents. Objective UPPSP UPPS P Method fivestep five step process 1 experts Subsequently Swanson, Swanson "Swanson Nolan IV SNAPIV SNAP (SNAP-IV Child Inventory CABI (CABI them (CVI testretest test retest stability Results 80 evaluation 3, 3 (3 7 11 2 35 reassessed parameters McDonalds McDonald s 0.806 0806 0 806 Cronbachs Cronbach 0.801, 0801 0.801 , 801 0.801) 0.838 0838 838 0.836, 0836 0.836 836 0.836) 0.826 0826 826 0.810, 0810 0.810 810 0.810) 0.800 0800 800 0.799 0799 799 0.936 0936 936 0.934. 0934 0.934 . 934 0.934) assessments Conclusions 8 ( 0.80 080 0.83 083 83 0.82 082 82 081 0.81 81 0.79 079 79 0.93 093 93 0.8 08 0.7 07 0.9 09 9 0.

Abstract This study aims to analyze the mechanisms through which the coronavirus disease (COVID-19) pandemic impacts on well-being at work and on productivity. The secondary objective is to identify stress management strategies for the work environment during the pandemic. This is an integrative review. Phase 1 consisted of searches of open access electronic databases (MEDLINE, SciELO, Bireme, and LILACS) for papers published in 2020 addressing mental health, work, and pandemics. Phase 2 consisted of selecting literature recommended by specialists in occupational psychiatry and positive psychology. These materials were read and critically analyzed. Forty references were included in the literature review. The articles reviewed were classified into the following categories: articles concerning work relationships in Brazil; articles describing the impact of pandemics on mental health and work; articles focusing on the work of health professionals during pandemics; articles about well-being at work; and papers proposing strategies to improve well-being and productivity and to promote mental health. The COVID-19 pandemic can have a significant impact on workers’ mental health and productivity. Most professionals face a need to adapt to changes, which can decrease their feeling of well-being. Consequently, strategies to promote well-being and mental health in the work environment should be a priority. Work routines were modified after the COVID-19 pandemic set in and assessing these changes is essential to maintain workers’ mental health. By so doing, it is possible to promote general well-being and post-traumatic recovery and reduce stress levels.

Abstract Introduction The existence of a general factor related to psychiatric symptoms is supported by studies using a variety of methods in both clinical and non-clinical samples. Objectives This study aims to evaluate the replicability of the internal structure of the Brief Symptom Inventory in a large Brazilian sample. Methods Participants were 6,427 Brazilian subjects (81% female). Mean age was 42.1 years (standard deviation [SD] = 13.6, Min = 13, Max = 80). All participants completed the online version of the Brief Symptom Inventory. This scale presents a general score (GSI) and nine specific clusters of symptoms (depression, anxiety, phobic anxiety, interpersonal sensibility, psychoticism, paranoid ideation, obsessive-compulsive behavior, hostility, and somatization symptoms). Results Confirmatory factor analysis was performed to assess the factor structure of the BSI. The results showed that the best-fitting model was a bifactor solution and the general factor was the main dimension explaining most of the reliable variability in the data. Conclusion The findings suggest that the BSI’s internal structure was replicated in a non-clinical sample and that the general factor is the most reliable score. However, it is necessary to better understand the meaning of the general factor scores in a non-clinical sample to increase interpretability of scores.

Abstract Introduction Emotion regulation refers to use of strategies to change or suppress a response to an affective experience and is an important component of an individual’s subjective wellbeing. Difficulties properly regulating emotions are related to psychopathological processes. Objective This study assessed the factor structure of the Brazilian version of the Emotion Regulation Questionnaire (ERQ); the invariance of its psychometric parameters as a function of gender; and its convergent validity with other scales measuring affective processes. Method A total of 813 adults (73.7% women), aged between 18 and 64 years and with a high educational level used an electronic platform to complete the ERQ, the Positive and Negative Affect Schedule (PANAS), the Affect Scale (AS), and the Difficulties in Emotion Regulation Scale (DERS). Factor structure, reliability, and validity of the adapted version of the ERQ were investigated. Results Multi-group confirmatory factor analysis (MGCFA) revealed adequate goodness of fit for the ERQ’s two-factor model (cognitive reappraisal and emotional suppression), providing evidence of invariance of its psychometric parameters as a function of gender. Correlations between the ERQ’s factors and measures of affect and emotional dysregulation presented positive indicators, with significant associations between emotion regulation and affective experiences depending on gender. Conclusion The ERQ presents good psychometric indicators for use with the Brazilian population.

Abstract Background: Children and adolescents are considered a population at risk for developing posttraumatic stress disorder (PTSD) after a traumatic event. The Children's Revised Impact Scale (CRIES-8) is a self-report scale with 8 items that investigates avoidance and intrusion behaviors related to posttraumatic stress symptoms. Objective: The study consisted of translation and transcultural adaptation of CRIES-8 to Brazilian Portuguese and evaluation of its psychometric properties. Methods: A sample of 235 Brazilian children and adolescents exposed to natural hazards (drought or flood) and non-exposed children participated in the study. The methodological procedure for translation and cultural adaptation were in accordance with the principles described by ISPOR Task Force for Translation and Cultural Adaptation. We also evaluated test reliability and validity based on test content, the relations to other variables, and internal structure. Results: The procedures lead to a final Portuguese version proofread and cultural-adapted. Empirical evidence supports CRIES-8's division in two latent constructs (Intrusion and Avoidance), as well convergence correlations with other measures of child mental health and high reliability. Discussion: A Brazilian-Portuguese version of CRIES-8 is an important tool for a better screening of PTSD among youth who face traumatic events, being a potential informative instrument to identify children at risk.

Abstract Background: Semantic memory is a cultural influenced cognitive domain that is responsible for our knowledge about words and the world. Semantic Memory Battery (BAMS) is a new battery that evaluate semantic memory based on a compendium of tasks, including verbal fluency, naming, conceptualization, categorization, general questions, and word definitions, and was designed to consider cultural aspects. Objectives: We aimed to evaluate the BAMS psychometrics structure comprising classical and modern analysis, and also evaluate a clinical subdivision of the battery. Methods: 114 Brazilian cognitively healthy older adults BAMS performance provided data for psychometric analysis using validity tests, item response theory analysis and confirmatory factor analysis for goodness-of-fit measures. Results: BAMS results revealed good validity and good-fit measures in each subtest, total score (X2 = 20.684, p = 0.110) and a hierarchical structure with clinical subdivision of the battery (X2 = 20.089, p = 0.093). Discussion: BAMS is a new compendium of tasks that evaluate distinct aspects of semantic memory and can clinically consider the impact of executive function. This battery evaluates verbal fluency, naming, conceptualization, categorization, general knowledge and word definitions. The BAMS has clinical importance once semantic memory is mostly influenced by culture and language, and there is an absence of broadly semantic memory tests in our scenario, especially with older adults that can have a pathological aging condition that affects primarily or secondarily this domain.

RESUMO O presente estudo avalia a associação entre velocidade de processamento, funções executivas e memória em uma amostra de diferentes faixas etárias. O estudo testa a hipótese de que a velocidade de processamento, as funções executivas e a memória apresentam associação mais forte na infância e na velhice. Avaliamos 571 participantes, com idade entre seis e 92 anos, divididos em quatro grupos etários: crianças/adolescentes, adultos jovens, adultos de meia-idade e idosos. Análises de correlação sugerem que a variância compartilhada entre velocidade de processamento e memória é forte na infância e fraca nas demais idades. Já as funções executivas apresentaram associação forte com a memória tanto na infância quanto na velhice, quando comparadas aos estágios intermediários. Concluímos que os efeitos da atenção sobre a memória variam em função da idade do participante. Essas funções podem ser mecanismos compensatórios para a memória ao longo do desenvolvimento.

ABSTRACT The present study evaluated the association between episodic memory, executive function and processing speed in a sample with different age ranges. We tested the hypothesis that processing speed, executive function and memory are more strongly associated during childhood and old age. We evaluated 571 participants, aged six to 92 years, divided into four age groups: children/adolescents, young adults, middle-aged adults and older adults. Correlation analyses suggested that the shared variance between the processing speed and memory is strong in childhood but weak across other age ranges. Executive function, however, had a stronger association both in childhood and in old age, when compared with the intermediate stages. We conclude that the effects of processing speed and executive function on memory are not stable across human development. These functions may be compensatory mechanisms for memory functioning in childhood and old age.

RESUMO A motivação do atleta é considerada um dos elementos mais importantes para obter sucesso na carreira esportiva. O objetivo deste estudo foi comparar o nível de motivação de atletas de futebol com alto tempo jogado (ATJ) e baixo tempo jogado (BTJ) em uma competição. Foram avaliados 112 atletas federados (18,58±1,06 anos de idade) participantes do Campeonato Mineiro de futebol sub-20 (2015). Foi utilizada a Escala de Motivação no Esporte (SMS). O tempo jogado (TJ) pelos atletas na fase classificatória do campeonato foi registrado por meio da análise das 48 súmulas oficiais. Os atletas foram agrupados de acordo com o TJ, sendo BTJ ≤25% (≤184 minutos) e ATJ ≥75% (≥513 minutos). Os resultados evidenciaram que os atletas com ATJ apresentaram maiores índices de autodeterminação e maiores níveis de motivação intrínseca, em comparação aos atletas com BTJ (p<0,05), bem como atletas com BTJ se mostraram mais desmotivados nesta competição (p<0,05). Conclui-se que os atletas com ATJ em partidas oficiais apresentam maiores índices de autodeterminação e maiores níveis de motivação intrínseca. Por outro lado, atletas com BTJ em partidas oficiais apresentam uma desmotivação maior quando comparados com os atletas com ATJ.

ABSTRACT An athlete’s motivation is deemed one of the most important elements to achieve success in sports career. The aim of this study was to compare the motivation level of football athletes with long playtime (LPT) and short playtime (SPT) in a competition. The study assessed 112 federated athletes (18.58±1.06 years old) participating in Minas Gerais’s Under-20 Football Championship (2015), by means of the Sport Motivation Scale (SMS). The athletes’ playtime (PT) in the championship’s qualifying rounds was registered through the analysis of 48 official referee report forms. The athletes were grouped according to their PT - SPT ≤25% (≤184 minutes) and LPT ≥75% (≥513 minutes). Results showed that those with LPT presented higher levels of self-determination and higher scores of intrinsic motivation compared to SPT athletes (p<0.05), and SPT athletes seemed less motivated in said competition (p<0.05). In conclusion, LPT athletes in official matches scored higher in self-determination and intrinsic motivation levels. On the other hand, those with SPT in official games showed higher demotivation compared to the former.

Resumo Introdução Na avaliação de idosos com educação formal muito baixa, os testes típicos de atenção seletiva e controle inibitório são enviesados devido à dependência de habilidades básicas de leitura. Nesse sentido, pretende-se avaliar as características psicométricas do Teste dos Cinco Dígitos (Five Digits Test, FDT), teste de paradigma Stroop-numérico, em idosos sem transtornos cognitivos, em pacientes com comprometimento cognitivo e em pacientes com demência. Métodos Foram avaliados 211 idosos brasileiros com baixa escolarização formal por meio do FDT e outras medidas cognitivas. Analisamos a validade de construto e a confiabilidade por correlações e consistência interna. Resultados O FDT apresentou correlações fracas com testes de inteligência cristalizada e correlações de moderadas ou fortes com medidas de inteligência fluida, medidas cognitivas globais e testes de funções executivas. O teste apresentou consistência interna elevada (>0.900). Conclusão Em conjunto, os resultados sugerem que o FDT é uma medida válida e confiável para a avaliação da velocidade de processamento e funções executivas em idosos com baixa escolaridade.

Abstract Introduction In the assessment of older adults with very low formal education, typical tests of selective attention and inhibitory control are biased by reading abilities. In this sense, we aim to assess the psychometric characteristics of the Five Digits Test (FDT), a numerical Stroop paradigm, in older adults without cognitive disorders, with mild cognitive impairment, and with dementia. Methods We assessed 211 Brazilian older adults with low formal education using the FDT and other cognitive measures. Construct validity and reliability were assessed by correlations and internal consistency. Results The FDT test had weak correlations with crystalized intelligence tests and moderate-high correlations with fluid intelligence measures and tests of global cognitive status and executive functions. The split-half coefficient of reliability showed high internal consistency (>0.900). Conclusion Together, the results suggest that the FDT is a valid and reliable measure for the assessment of processing speed and executive functions in older adults with low formal education.

Resumo Objetivo: Tradução, adaptação transcultural para o português brasileiro e aplicação da escala Alzheimer’s Disease Cooperative Study - Activities of Daily Living (ADCS-ADL) como instrumento de triagem cognitiva. Método: Retrotradução associada ao método bilíngue e de pré-teste. A amostra foi constituída por 95 idosos e seus respectivos acompanhantes, sendo 30 controles, 32 portadores de comprometimento cognitivo leve (CCL) e 33 portadores de demência de Alzheimer (DA) em fase inicial. Resultados: Um pequeno número de modificações ocorreu na escala. O coeficiente alpha de Cronbach foi 0,89. O grupo controle pontuou 72,9, seguido pelo CCL (65,1) e pelo DA (55,9), valor p<0,001. A curva ROC demonstrou valor de 0,89. Com o ponto de corte de 72, observamos sensibilidade de 86,2%, especificidade de 70%, valor preditivo positivo de 86,2%, valor preditivo negativo de 70%, razão de verossimilhança positiva de 2,9 e razão de verossimilhança negativa de 0,2. Conclusão: A escala ADCS-ADL apresenta propriedades psicométricas satisfatórias para discriminar entre DA, CCL e cognição normal.

Summary Objective: Translate, transcultural adaptation and application to Brazilian Portuguese of the Alzheimer’s Disease Cooperative Study - Activities of Daily Living (ADCS-ADL) scale as a cognitive screening instrument. Method: We applied the back translation added with pretest and bilingual methods. The sample was composed by 95 elderly individuals and their caregivers. Thirty-two (32) participants were diagnosed as mild cognitive impairment (MCI) patients, 33 as Alzheimer’s disease (AD) patients and 30 were considered as cognitively normal individuals. Results: There were only little changes on the scale. The Cronbach alpha coefficient was 0.89. The scores were 72.9 for control group, followed by MCI (65.1) and by AD (55.9), with a p-value < 0.001. The ROC curve value was 0.89. We considered a cut point of 72 and we observed a sensibility of 86.2%, specificity of 70%, positive predictive value of 86.2%, negative predictive value of 70%, positive likelihood ratio of 2.9 and negative likelihood ratio of 0.2. Conclusion: ADCS-ADL scale presents satisfactory psychometric properties to discriminate between MCI, AD and normal cognition.

Abstract Background Passionate love involves physiological, emotional, and cognitive features that greatly changes behavior. This phenomenon seems universal or near universal. Even other animal species choose partners. An intense state of passionate love is associated with activity in dopamine pathways of the brain ‘reward system’, and recently has been regarded as a ‘natural addiction’. Instruments or tools to evaluate romantic love during childhood is still scarce. Objective To perform the translation and cultural adaptation of the Juvenile Love Scale (JLS) for use in the Brazilian context targeted for adolescents between 14 and 18 years old. Methods The translation and cultural adaptation of JLS followed international recommendations, and its content validity was analyzed by a panel of experts in different areas of knowledge. Results The final version of the JLS for use in the Brazilian context showed high content validity (> 90%). Discussion To our knowledge, this is the first scale for measuring romantic or passionate love in adolescents adapted to the Brazilian context. This instrument is a significant contribution to the study of the dimensions of love, as well as to understand the impact of love on the psychiatric phenomena that pervade life in this stage of development.

Objetivo : A avaliação de habilidades visioespaciais e de memória por tarefas como a Figura Complexa Taylor (FCT) é enviesada para de idosos com baixa escolarização formal. Propomos uma versão "simplificada" da FCT (FCTs) projetada para a avaliação dos idosos com baixo nível educacional e apresentamos evidências preliminares de suas propriedades psicométricas. Métodos : Avaliamos uma amostra heterogênea de idosos saudáveis e pacientes com comprometimento cognitivo leve e demência por Doença de Alzheimer usando a FCTs e outras medidas neuropsicológicas. Resultados : Nossos resultados sugerem que a cópia de teste, a evocação imediata e a evocação tardia têm alta concordância entre avaliadores e elevada consistência interna, apresentam correlações significativas com outros testes de habilidades visioespaciais, memória e inteligência, além de documentarem diferenças significativas entre o grupo controles e os pacientes. Conclusão : Nosso estudo apresenta uma nova medida para a avaliação neuropsicológica de idosos com baixa escolaridade, com evidências promissoras de validade e confiabilidade

Objective : The assessment of visuospatial abilities and memory using tasks such as the Taylor Complex Figure Task (TCFT) is biased for older adults with low formal education. We devised a "Simplified" version of the TCFT designed to assess older adults with low educational background and provide preliminary evidence of its psychometric properties. Methods : We evaluated a heterogeneous sample of healthy older adults and patients with mild cognitive impairment and Alzheimer's disease dementia using the simplified TCFT and other neuropsychological measures. Results : Our results suggest that the test copy, immediate and delayed recall have high inter-rater agreement and internal consistency, significant correlations with other tests of visuospatial abilities, memory and intelligence, and also detected significant group differences between controls and patients. Conclusion : Our study presents a new measure for assessing low-educated elderly with promising evidence of validity and reliability.

Abstract Background Considering the importance of Executive Functions to clinical and nonclinical situations, Barkley proposed a new theory of executive functioning based on an evolutionary neuropsychological perspective and clinical research using large samples of clinical and community identified adults and children as well as children with ADHD followed to adulthood. Objective The present study aims to adapt the Barkley Deficits in Executive Functions Scales (BDEFS) to Brazilian Portuguese and also assess its construct validity in a sample of normal Brazilian adults. Methods The original version of scale was adapted to Brazilian Portuguese according to the guideline from the ISPOR Task Force. To assess the semantic equivalence between the original and adapted version, both of them were applied into a sample of 25 Brazilian bilingual adults. Finally, 60 Brazilian adults completed the BDEFS and the Brazilian versions of Barratt Impulsiveness Scale (BIS-11) and Adult Self-Report Scale (ASRS-18) to assess convergent validity. Results The BDEFS Brazilian Portuguese version has semantic correspondence with the original version indicating that the adaptation procedure was successful. The BDEFS correlated significantly with the impulsivity and attention scores from the BIS-11 and ASRS-18 supporting its construct validity. Cronbach’s alpha (α = 0.961) indicated that the BDEFS translated version has satisfactory internal consistency. Discussion Together, these findings indicate the successful adaptation of the BDEFS to Brazilian Portuguese and support its utility in that population.