Abstract Objective: To describe the speech pattern of patients with hereditary Spastic Paraplegia type 4 (SPG4) and correlated it with their clinical data. Methods: Cross-sectional study was carried out in two university hospitals in Brazil. Two groups participated in the study: the case group (n = 28) with a confirmed genetic diagnosis for SPG4 and a control group (n = 17) matched for sex and age. The speech assessment of both groups included: speech task recording, acoustic analysis, and auditory-perceptual analysis. In addition, disease severity was assessed with the Spastic Paraplegia Rating Scale (SPRS). Results: In the auditory-perceptual analysis, 53.5% (n = 15) of individuals with SPG4 were dysarthric, with mild to moderate changes in the subsystems of phonation and articulation. On acoustic analysis, SPG4 subjects’ performances were worse in measurements related to breathing (maximum phonation time) and articulation (speech rate, articulation rate). The articulation variables (speech rate, articulation rate) are related to the age of onset of the first motor symptom. Conclusion: Dysarthria in SPG4 is frequent and mild, and it did not evolve in conjunction with more advanced motor diseases. This data suggest that diagnosed patients should be screened and referred for speech therapy evaluation and those pathophysiological mechanisms of speech involvement may differ from the length-dependent degeneration of the corticospinal tract. Objective SPG (SPG4 Methods Crosssectional Cross sectional Brazil n 28 17 included recording analysis auditoryperceptual auditory perceptual addition SPRS. SPRS . (SPRS) Results 535 53 5 53.5 15 dysarthric subjects maximum time rate rate. symptom Conclusion diseases lengthdependent length dependent tract (SPG 2 1 (SPRS 53.

RESUMO Introdução A doença de Parkinson (DP) é a segunda doença neurodegenerativa mais prevalente no mundo, com predomínio de sintomas motores e não motores. Dentre estes, destaca-se a disfagia. Objetivo Realizar a revisão sistemática da literatura que trata das avaliações clínicas não instrumentais disponíveis para rastreio e avaliação da disfagia em indivíduos com DP. Estratégia de pesquisa Para a seleção dos estudos, foram utilizados os descritores Parkinson disease, swallowing, dysphagia, deglutition disorders, questionnaire, health surveys, evaluation, screening e assessment, em combinações variadas, nas seguintes bases de dados: PubMed, Biblioteca Cochrane e SciELO. Critérios de seleção Artigos em inglês, português e espanhol, publicados no período de janeiro de 2006 a julho de 2016, cuja abordagem metodológica atendesse ao objetivo desta revisão. Dois revisores independentes analisaram os artigos, a fim de verificar a elegibilidade. Quando houve discordância, o consenso foi alcançado pela avaliação de um juiz que não conhecia as avaliações anteriores. Resultados Foram encontrados 846 artigos. Após consideração dos critérios de inclusão/exclusão e análise do juíz, apenas 4 estudos foram analisados, nos quais foram utilizados 4 instrumentos diferentes, todos eles questionários de autopercepção da disfagia. Não houve nenhum instrumento que tivesse realizado avaliação clínica da disfagia com oferta de alimentos. Conclusão Verificou-se que não existem instrumentos de rastreio e de avaliação clínica da disfagia em paciente com DP que utilizem oferta de alimento e não somente auto-percepção do paciente, no período que compreendeu o levantamento bibliográfico deste estudo.

ABSTRACT Introduction Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease in the world, with a predominance of motor and non-motor symptoms. Among these, dysphagia stands out. Purpose Systematically review the non-instrumental clinical evaluations available for the screening and assessment of dysphagia in individuals with PD. Research strategy For the selection of the studies, we used the descriptors: Parkinson disease, swallowing, dysphagia, deglutition disorders, questionnaire, health surveys, evaluation, screening, and evaluation, in a variety of combinations, aiming at a greater number of studies. The databases were PubMed, Cochrane Library, and SciELO. Selection criteria Articles published in English, Portuguese, and Spanish that were published between January 2006 and July 2016 were selected, whose methodological approach met the objective of this review. A descriptive analysis was performed. Two independent reviewers reviewed the articles in order to verify the eligibility. When there was disagreement, a consensus was reached by the evaluation of a judge who did not know the previous evaluations. Results Eight hundred forty-six articles were founded. After considering the inclusion/exclusion criteria and the judge’s analysis, only four studies were analyzed, which were four different instruments, and all of the instruments were self-perception questionnaires of dysphagia. There was no instrument that performed a clinical evaluation of dysphagia with the food supply. Conclusion It has been verified there are no instruments for the screening and clinical evaluation of dysphagia in patients with PD who use a food supply and not only the self-perception of the patient in the period that included the bibliographic survey of this study.