RESUMO JUSTIFICATIVA E OBJETIVOS Fibromialgia é caracterizada por dor difusa, que pode comprometer a qualidade de vida autorrelatada (QVAR). Sabe-se pouco sobre a influência de fatores psicossociais e ambientais na QVAR em mulheres com fibromialgia. O objetivo deste estudo foi investigar fatores relacionados à QVAR entre mulheres com fibromialgia, segundo o domínio da Classificação Internacional de Funcionalidade. MÉTODOS Estudo transversal de base populacional realizado com 1.557 mulheres. Aquelas que se autorrelataram com fibromialgia responderam ao Índice de Impacto da Fibromialgia (n=115). A QVAR foi avaliada por questões que variavam de 1 (insatisfeita) a 3 (muito satisfeita). As exposições incluíram fatores pessoais e ambientais distribuídos em quatro blocos de acordo com a influência hipotética no desfecho. Foi realizada regressão linear múltipla, considerando 95% do intervalo de confiança, utilizando-se a versão 24 do IBM SPSS. RESULTADOS Suficiência de renda foi relacionada à maior QVAR no modelo 1. Ambiente físico estava relacionado à QVAR nos modelos 2, 3 e 4. Medição da capacidade funcional esteve relacionada à QVAR no modelo 4. Apenas sintomas depressivos (ß:-0,374; IC: -0,037/ -0,004) e número de áreas corporais dolorosas (ß: 0,204; IC: -0,102/-0,001) mantiveram-se significativamente relacionado à QVAR, explicando 27% da variância. CONCLUSÃO QVAR esteve relacionada a sintomas depressivos e número de áreas corporais dolorosas mesmo depois de controlada por condição socioeconômica, ambiental e saúde. Outros aspectos podem mediar esse desfecho, merecendo atenção na abordagem biopsicossocial. Os resultados destacaram relevância dos aspectos biopsicossociais na qualidade de vida das mulheres com fibromialgia, recorrendo a fatores que poderiam ser abordados na prática clínica para promover saúde e bem-estar.

ABSTRACT BACKGROUND AND OBJECTIVES Fibromyalgia is characterized by diffuse pain, which may compromise the self-rated quality of life (SRQoL). Little is known about the influence of psychosocial and environmental factors on SRQoL in women with fibromyalgia. The objective was to investigate factors related to SRQol among women with fibromyalgia, according to International Classification of Functioning domain. METHODS A cross-sectional population-based study was performed with 1,557 women. Those who self-reported fibromyalgia answered the Fibromyalgia Impact Index. SRQoL was evaluated by questions ranging from 1 (unsatisfied) to 3 (very satisfied). Exposures included personal and environmental factors distributed in four blocks according to hypothesized influence on outcome. Multiple linear regression was performed, considering 95% of confidence interval, using IBM SPSS version 24. RESULTS Income sufficiency was related to higher SRQoL in model 1. Physical environment was related to SRQoL in model 2, 3 and 4. Functional capacity measurement was related to SRQoL in model 4. In the final model, only depressive symptoms (ß:-0.374; CI: -0.037/ -0.004) and number of painful body areas (ß: 0.204; CI: -0.102/-0.001) remained significantly related to SRQoL, explaining 27% of the variance. CONCLUSION SRQoL was related to depressive symptoms and number of painful body areas even after controlled by socioeconomic, environment and health status. However, other aspects may mediate or moderate that outcome, deserving attention in a biopsychosocial approach. The results highlighted the relevance of biopsychosocial aspects on quality of life of women with fibromyalgia, addressing factors that could be approached in clinical practice to promote health and well-being.

Abstract Background: Fibromyalgia syndrome (FMS) is both a challenging and disabling condition. The International Association for the Study of Pain (IASP) classifies FMS as chronic primary pain, and it can negatively impact individuals’ functioning including social, psychological, physical and work-related factors. Notably, while guidelines recommend a biopsychosocial approach for managing chronic pain conditions, FMS assessment remains clinical. The WHODAS 2.0 is a unified scale to measure disability in the light of the International Classification of Functioning, Disability and Health. Thus, this study aimed to evaluate the reliability and validity of the Brazilian version of WHODAS 2.0 for use in individuals with FMS. Methods: Methodological study of the validity and reliability of the Brazilian version of the 36-item WHODAS 2.0 with 110 individuals with FMS. The instrument gives a score from 0 to 100, the higher the value, the worse the level of functioning. We assessed participants with Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) (0–100), Fibromyalgia Impact Questionnaire (FIQ) (0–10) and Beck Depression Inventory instrument (BDI) (0–63). The construct validity, internal consistency, and test–retest stability. We used SF-36, FIQ and BDI to study construct validity analysis. For statistical analysis, we performed the intraclass correlation (ICC), Spearman correlation, and Cronbach's alpha, with a statistical level of 5%. Results: Most participants were female (92.27%), aged 45 (± 15) years. The test–retest reliability analysis (n = 50) showed stability of the instrument (ICC = 0.54; ρ = 0.84, p < 0.05). The test–retest correlation between the domains was moderate to strong (ρ > 0.58 and < 0.90). Internal consistency was satisfactory for total WHODAS 2.0 (0.91) and also for domains, ranging from 0.44 to 0.81. The construct validity showed satisfactory values with all moderately correlated with WHODAS 2.0 instruments (> 0.46 and < 0.64; p < 0.05). WHODAS 2.0 evaluates the functioning encompassing components of health-related quality of life, functional impact, and depressive symptoms in those with FMS. Conclusions: WHODAS 2.0 is a reliable and valid instrument to evaluate functioning of Brazilians with FMS. It provides reliable information on individuals’ health through of a multidimensional perspective, that allows for individual-centered care.

O objetivo deste estudo foi verificar a ocorrência de depressão e alterações da qualidade de vida (QV) em indivíduos com artrite reumatoide (AR).Participaram da pesquisa 60 indivíduos, divididos em 2 grupos com 30 cada, sendo o Grupo Teste composto por indivíduos com AR e o Grupo Controle composto por indivíduos com saúde estável. A QV foi avaliada pelo Medical Outcomes Study 36-Item Short-Form Healthy Survey (SF-36) e a depressão, pela Escala de Depressão de Beck (BDS). Para estabelecer comparações entre os grupos quanto aos escores de cada domínio do SF-36, utilizamos o teste de Mann-Whitney e, para os dados do "estado de saúde em geral" do SF-36, o teste do χ². Para comparar os grupos quanto ao escore total de depressão e quanto aos escores de cada categoria de depressão, empregamos respectivamente os testes Wilcoxon-Mann-Whitney (WMW) e χ². Para as variáveis "estado de saúde" em geral do SF-36 e classificação da depressão, calculou-se a Odds Ratio bruta e ajustada por meio de modelagem de regressão logística. O nível de significância foi estabelecido em 5%. Os resultados mostraram que houve diferenças entre os grupos nos oito domínios do SF-36, indicando queindivíduos com AR apresentam menores índices de QV e autoavaliação em saúde (ORajustada=14,38) e que 63,33% dos participantes com AR apresentam algum grau de depressão. Concluímos que a AR causa um impacto negativo na QV e que a depressão poder ser considerada um sintoma associado à diminuição da capacidade funcional decorrente da doença.

The objective of this study was to verify the depression occurrence and changes in quality of life (QoL) in individuals with rheumatoid arthritis (RA). Sixty individuals took part of the study, who were divided into 2 groups with 30 participants each. The Test Group had RA patients, and the Control Group had stable health individuals. QoL was assessed by the Medical Outcomes Study 36-Item Short-Form Healthy Survey (SF-36) and depression was evaluated by means of the Beck Depression Scale (BDS). In order to make comparisons between the groups regarding the scores of each SF-36 domain, we used the Mann-Whitney test and for the "general health" data of the SF-36, the χ² test was applied. In order to compare the groups regarding the total score of depression and scores of each category of depression, the Wilcoxon-Mann-Whitney (WMW) and χ² testswere used, respectively. For the general "health state" variables of the SF-36 and classification of depression, we calculated the crude and adjusted Odds Ratio through logistic regression modeling. The significance level was set at 5%. The results showed that there were differences among the groups for the eight SF-36 domains, indicating that individuals with RA present lower rate of QoL and self-evaluation in health (adjusted OR=14.38) and that 63.33% of the participants with RA present some degree of depression. We concluded that RA causes a negative impact in the QoL and the depression can be considered a symptom associated to the decrease of the functional capacity due to the disease.

El objetivo de este estudio fue verificar la ocurrencia de depresión y alteraciones de la calidad de vida (CV) en individuos con artritis reumatoidea (AR). Participaron de la investigación 60 individuos, divididos en 2 grupos de 30, siendo el Grupo Test compuesto por individuos con AR y el Grupo Control compuesto por individuos con salud estable. La CV fue evaluada por el Medical Outcomes Study 36-Item Short-Form Healthy Survey (SF-36) y la depresión, por la Escala de Depresión de Beck (BDS). Para establecer comparaciones entre los grupos en cuanto a los escores de cada dominio del SF-36, utilizamos el test de Mann-Whitney u, para los datos del "estado de salud en general" del SF-36, el test del χ². Para comparar los grupos en cuanto al escore total de depresión y en cuanto a los escores de cada categoría de depresión, empleamos respectivamente los tests Wilcoxon-Mann-Whitney (WMW) y χ². Para las variables "estado de salud" en general del SF-36 y clasificación de la depresión, se calculó la Odds Ratio bruta y ajustada por medio de modelado de regresión logística. El nivel de significancia fue establecido en 5%. Los resultados mostraron que hubo diferencias entre los grupos en los ocho dominios del SF-36, indicando que individuos con AR presentan menores índices de CV y autoevaluación en salud (OR ajustada=14,38) y que 63,33% de los participantes con AR presentan algún grado de depresión. Concluimos que la AR causa un impacto negativo en la CV y que la depresión puede ser considerada un síntoma asociado a la disminución de la capacidad funcional resultante de la enfermedad.