Energy drinks are nonalcoholic beverages whose main ingredients are sugar, taurine, and caffeine. The consumption of energy drinks is increasing worldwide, but only a few conflicting studies have investigated the vascular effects of energy drinks in young adults. The aim of this study was to evaluate microvascular reactivity before and after energy drinks consumption in young healthy male volunteers. This was a cross-sectional prospective study. Microvascular reactivity signals were evaluated in the skin of the forearm using laser speckle contrast imaging with acetylcholine (ACh) iontophoresis before and 90 and 180 min after the randomized consumption of one ED or the same volume of water (control), followed by a postocclusive reactive hyperemia (PORH) test. Thirty-two volunteers were evaluated (age: 25.4±4.3 years). Energy drink consumption prevented the rest-induced reduction in cutaneous vascular conductance over time that was observed in the control group. In the control group, there were significant reductions in microvascular vasodilation at 90 and 180 min compared to baseline (P=0.004), but this was not the case in the energy drink group (P=0.76). Our results demonstrated that the reduction in microvascular conductance associated with prolonged immobility can be prevented by the consumption of one energy drink, highlighting the vasodilator effects of this beverage in young individuals at rest. The between-study variability in terms of the brand of energy drinks and the ingested volume, as well as the method of vascular evaluation and the inclusion criteria, may explain the discrepancies among previous studies on the vascular effects of energy drinks. sugar taurine caffeine worldwide adults crosssectional cross sectional ACh (ACh 9 18 control, , (control) PORH (PORH test Thirtytwo Thirty two age (age 25443 25 4 3 25.4±4. years. years . years) restinduced rest induced P=0.004, P0004 P P=0.004 0 004 (P=0.004) P=0.76. P076 P=0.76 76 (P=0.76) betweenstudy between criteria 1 (control 2544 2 25.4±4 P000 P=0.00 00 (P=0.004 P07 P=0.7 7 (P=0.76 254 25.4± P00 P=0.0 (P=0.00 P0 P=0. (P=0.7 25.4 (P=0.0 P=0 (P=0. 25. P= (P=0 (P= (P

RESUMO O objetivo deste estudo foi testar a viabilidade de uma nova ferramenta de software informático para avaliação da lassitude articular passiva da articulação coxofemoral. A lassitude articular da articulação coxofemoral foi estimada usando-se um programa informático especial, desenvolvido para o efeito, por dois avaliadores, um com treino prévio e outro não treinado, na medição do índice de distração, em duas sessões independentes, utilizando-se 230 articulações coxofemorais de 115 cães, as quais efetuaram o rastreio de displasia coxofemoral realizando a projeção de distração da articulação coxofemoral. Previamente, todas as radiografias foram enviadas para o PennHIP Analysis Center, para se obter uma medida oficial do índice de distração. A repetibilidade das medições das duas sessões foi adequada para ambos os avaliadores. A reprodutibilidade do índice de distração oficial, média±desvio-padrão 0,44±0,15, foi adequada (P>0,05) para o avaliador treinado, 0,44±0,15, e não adequada (P>0,05) para o avaliador não treinado, 0,47±0,17. A ferramenta de medição do índice de distração proposta pode ser usada com segurança na medição do índice de distração por avaliadores treinados, uma vez que mostra uma adequada repetibilidade e reprodutibilidade das medições oficiais do índice de distração. A simplicidade do processo apresentado torna-o menos demorado e mais econômico.

ABSTRACT The aim of this study was to test the accuracy of a new automated computer software tool for the assessment of passive hip laxity. The hip laxity was estimated using the dedicated computer software by two blinded evaluators, one previously trained and one without specific training for distraction index measurement, in two independent sessions using 230 hip joints from 115 dogs that underwent screening for passive hip laxity using the distraction view. Previously, all of these radiographs were sent to PennHIP Analysis Center for an official distraction index record. The measurement repeatability of the two sessions was adequate for both evaluators. The reproducibility of the official distraction index measurement, mean distraction index±standard deviation 0.44±0.15, was adequate (P>0.05) for the trained evaluator, 0.44±0.15, and non-adequate (P<0.05), for the non-trained evaluator 0.47±0.17. The distraction index measurement tool proposed can be used with confidence for hip laxity evaluation by trained evaluators, as it provided good repeatability and reproducibility of official reports. The simplicity of the process described leads to a less time-consuming and more affordable procedure.

The main goal of this study was to identify a set of factors considered relevant by basketball experts in a young player's route to high performance. The impossibility of choosing one as the most preponderant factor comes from the complex interaction between the different areas that influence the long development path of athletes to sport expertise. Our sample consisted of 14 coaches (7 of men's level and 7 of youth level), 7 players and 7 club coordinators who were asked to give their view on the subject by means of an interview. One of the main conclusions was the decisive influence of environmental factors, especially the family and coaches' influence, both as promoters of the beginning of the activity and as the maintenance in it. Psychological factors - athlete's work ethic and surpassing capacity - were also referred as having a great role on this issue. Technical, tactical and physical factors (in this order of importance) come as an asset to the young athlete. Finally, we conclude that the training process should be defying and constantly adjusted to the athlete's needs, creating stimulus that allow the young player to develop strategies to read and understand of the game, as well as decision making processes. The context where the athlete is inserted, as well as the psychological aspects and knowledge of the game must be considered the most relevant factors.

O principal objetivo deste estudo foi identificar um conjunto de fatores considerados relevantes por especialistas de basquetebol no percurso de um jovem jogador para o alto rendimento. A impossibilidade de escolher um único fator como o mais preponderante advém da complexa interação entre as diversas áreas que influenciam o caminho de desenvolvimento de longo dos atletas à experiência esportiva. A nossa amostra foi constituída por 14 treinadores (7 de nível dos homens e 7 do nível da juventude), 7 jogadores e 7 coordenadores do clube que foram convidados a dar a sua opinião sobre o tema por meio de uma entrevista. Uma das principais conclusões foi a influência decisiva de fatores ambientais, especialmente a influência da família e treinadores, ambos como promotores do início da atividade e quanto à manutenção na modalidade. Os fatores psicológicos - ética de trabalho do atleta e capacidade de superação - também foram referidos como tendo um grande papel nesta questão. Fatores técnicos, táticos e físicos (por esta ordem de importância) são considerados mais-valias para o jovem atleta. Finalmente, podemos concluir que o processo de formação deve ser desafiante e constantemente ajustado às necessidades do atleta, criando estímulos que permitam ao jovem jogador desenvolver estratégias de leitura e compreensão do jogo, bem como os processos de tomada de decisão. O contexto em que o atleta está inserido, bem como os aspetos psicológicos e conhecimento do jogo devem ser considerados os fatores mais relevantes.

El objetivo principal de este estudio fue identificar un conjunto de factores considerados relevantes por los expertos de baloncesto en la ruta de un joven jugador de alto rendimiento. La imposibilidad de elegir uno como el factor más preponderante proviene de la compleja interacción entre las diferentes áreas que influyen en el camino de desarrollo a largo de los atletas a la experiencia deportiva. Nuestra muestra fue constituida por 14 entrenadores (7 del nivel de los hombres y el 7 de categoría juvenil), 7 jugadores y 7 coordinadores del club que proporcionaran su opinión sobre el tema por medio de una entrevista. Una de las principales conclusiones fue la decisiva influencia de los factores ambientales, especialmente la influencia de la familia y entrenadores, ambos como promotores de la inicio de la actividad y como el mantenimiento en el mismo. Los factores psicológicos - ética de trabajo del atleta y la capacidad de superación - también fueron referidos como teniendo un gran papel en este tema. Los factores técnicos, tácticos y físicos (en este orden de importancia) son considerados un activo para el joven atleta. Por último, llegamos a la conclusión de que el proceso de formación debe ser constantemente desafiante y ajustarse a las necesidades del atleta, debe proporcionar la creación de estímulos que permitan al joven jugador desarrollar estrategias para leer y entender del juego, así como los procesos de toma de decisiones. El contexto en el que se inserta el atleta, así como los aspectos psicológicos y conocimiento del juego se deben considerar los factores más relevantes.

Abstract Candida antarctica Lipase B (CALB) immobilized onto iron magnetic nanoparticles was evaluated as biocatalyst for the synthesis of flavor esters. Methyl and ethyl butyrate were synthesized by esterification of butyric acid with methanol and ethanol, respectively, in a medium containing solvent. The nanoparticles were produced by the co-precipitation method. The process parameters (type of solvent, temperature, substrate concentration, molar ratio, amount of biocatalyst, stirring speed and reaction time) were studied. The optimum conditions for both esters were achieved at 25 °C, 0.5 mol/L (methyl butyrate) and 0.4 mol/L (ethyl butyrate), molar ratio of 1:1, amount of biocatalyst: 10 mg, 150 rpm and 8 h of reaction, using heptane as solvent. Under those conditions, the maximum conversions of methyl butyrate and ethyl butyrate were higher than 90 %. The synthesis of flavor esters was also conducted by using Novozym® 435, a commercial catalyst, for comparison purposes.

Abstract Superparamagnetic nanomaterials have attracted interest in many areas due to the high saturation magnetization and surface area. For enzyme immobilization, these properties favor the enzyme-support contact during the immobilization reaction and easy separation from the reaction mixture by use of low-cost magnetic processes. Iron oxide magnetic nanoparticles (Fe3O4, MNPs), produced by the co-precipitation method, functionalized with 3-aminopropyltriethoxysilane (APTES) and glutaraldehyde (GLU), were evaluated as a solid support for Candida antarctica lipase B (CALB) immobilization. The nanomagnetic derivative (11nm) obtained after CALB immobilization (MNPs/APTES/GLU/CALB) was evaluated as biocatalyst in isoniazide (INH) synthesis using ethyl isonicotinate (INE) and hydrazine hydrate (HID) as substrates, in 1,4-dioxane. The results showed that MNPs/APTES/CALB had a similar performance when compared to a commercial enzyme Novozym 435, showing significant advantages over other biocatalysts, such as Rhizhomucor miehei lipase (RML) and CALB immobilized on non-conventional, low-cost, chitosan-based supports.

In this study, the phase behaviour of emulsified systems (oil + biosurfactant + water) was analyzed. The biosurfactant was produced in a 4-L batch bioreactor by Bacillus subtilis LAMI005, using residual glycerine from biodiesel production as a carbon source. Fourier Transform Infrared Spectroscopy (FT-IR), Nuclear Magnetic Resonance (NMR), and High Performance Liquid Chromatography (HPLC) analyses demonstrated that the biosurfactant produced by Bacillus subtilis (LAMI005) consists of a lipopeptide similar to surfactin. The influences of temperature and the composition of oil + biosurfactant + water were determined by using phase diagrams. Three types of oil were used, namely: motor oil, hydrogenated naphthenic oil (NH140) and castor bean oil. The emulsified systems were analyzed using optical micrography. The results presented here indicated that the biosurfactant produced in this work presents a potential use as stabilizing agent for oil-in-water emulsions.

During anatomical dissection of the abdominal cavity of an adult male corpse, a changing pattern of vascular supply of pancreas and of the transverse colon was observed. The inferior pancreatic artery and the middle colic artery arose from a common trunk of the superior mesenteric artery. Moreover, the lienal artery did not direct a dorsal branch to the neck of the pancreas, but rather sent two greater pancreatic arteries (proximal and distal) to the body of the gland and one caudal artery to the terminal portion of the pancreas. We also observed a large communicating branch between the proximal portion of the middle colic artery and the ascending branch of the left colic artery, previously described as artery of Moskowitz. Based on these data, clinical and surgical implications of these variations were highlighted.

Durante la disección anatómica de la cavidad abdominal del cadáver de un hombre adulto, se observó un patrón cambiante en el suministro vascular del páncreas y del colon transverso. La arteria pancreática inferior y la arteria cólica media surgían de un tronco común desde la arteria mesentérica superior. Además, la arteria esplénica no daba origen a la rama dorsal hasta el cuello del páncreas, más bien contaba con dos arterias pancreáticas mayores (una proximal y una distal) hasta la glándula, y una arteria caudal. También se observó una conexión entre la parte proximal de la arteria cólica media y el ramo ascendente de la arteria cólica izquierda lo que fue previamente definido como la arteria de «Moskowitz». Las implicaciones quirúrgicas de estas variaciones fueron destacadas en base a estos datos.

Delineou-se um experimento com o objetivo de analisar se as formas jovens de jundiá (Rhamdia quelen) realizam seletividade alimentar sobre os organismos zooplanctônicos, e como a dieta pode ser influenciada pela competição intra-específica. Os peixes foram mantidos em caixas de 5000 L e após sete dias do nascimento foram acondicionados nas unidades experimentais em diferentes densidades e abastecidos com água contendo plâncton (natural), permanecendo 24 horas no meio com alimento. Nos primeiros sete dias em densidades de 5 e 10 peixes/L, os peixes selecionaram mais intensamente os Rotifera, nas densidades de 20 e 40 peixes/L os Cladocera foram os mais selecionados. Aos 14 dias de idade os Cladocera foram os mais selecionados em todas as densidades de peixes. Aos 21 dias de idade as formas jovens de jundiá mantiveram a preferência por Cladocera e houve um aumento na captura de Copepoda na densidade de 40 peixes/L. Com 28 dias de idade os Cladocera foram os mais capturados nas densidades de 5 a 20 peixes/L, o consumo de Copepoda aumentou na densidade de 40 peixes/L. As formas jovens de Rhamdia quelen apresentaram uma alta preferência alimentar por Cladocera em todas as idades testadas (7; 14; 21 e 28 dias), no entanto, a densidade de peixes por litro têm influência sobre a captura do alimento preferencial. Verificou-se neste trabalho, que as formas jovens de jundiá apresentaram uma resposta mais rápida a presença de alimento em densidades superiores a 10 peixes/L, nas maiores densidades os peixes diminuíram as interações de defesa de território e formaram cardumes, o que permitiu um forrageamento de organismos zooplanctônicos maiores, mais ágeis e de maior lucro energético como Cladocera e Copepoda.

Experiments were designed to determine if the juvenile forms of jundia (Rhamdia quelen) exhibit selectivity feeding on zooplanktonic organisms and the influence of intraspecific competition on the diet. The fish were maintained in 5000-L containers, and after seven days from birth, they were acclimated in experimental units with different densities and supplied with water containing plankton (natural), where they remained for 24 h in the environment with food. In the first seven days at densities of 5 and 10 fish.L–1, the fish selected the Rotifera more intensely, and at densities of 20 and 40 fish.L–1, the Cladocera were more selected. At 14 days of age, the Cladocera were the most selected for all densities of fish. At 21 days of age, the juvenile forms of jundia maintained a preference for Cladocera, and there was an increase in the capture of Copepoda at a density of 40 fish.L–1. At 28 days of age, the Cladocera were the most captured at densities of 5 to 20 fish.L–1, and the consumption of copepods increased at a density of 40 fish.L–1. The juvenile forms of Rhamdia quelen showed a high feeding preference for Cladocera at all the ages tested (7, 14, 21 and 28 days), but the density of fish per litre influenced the capture of the preferential food. This study showed that the juvenile forms of jundia had a more rapid response to the presence of food at densities of more than 10 fish.L–1, and that at higher densities the fish decreased interactions of territorial defense and formed schools, which allowed the foraging of zooplanktonic organisms, larger in size, more agile and of greater energy gain, such as the Cladocera and copepods.

La violencia transcurre de los conflictos de autoridad, de las luchas por el poder, de la voluntad de dominio, deseo de aniquilamiento de otro o de sus bienes. Se debe considerar los impactos que los casos de violencia causan en los servicios de salud. Tuvo como objetivo identificar la percepción de los enfermeros de la Atención Básica acerca del fenómeno de la violencia doméstica y su relación con las familias. Es un estudio prospectivo, descriptivo y exploratorio, abordaje cualitativo, sustentado por la Teoría de Intervención "Práxica" de la Enfermería en Salud Colectiva; fueron propuestas tres categorías analíticas: concepto de familia, proceso de trabajo del enfermero en la Atención Básica y género. Fueron realizadas siete entrevistas en profundidad con enfermeras de Unidades Básicas de Salud en la región Metropolitana de São Paulo. Fue utilizada la técnica de Análisis de Discurso de Fiorin, emergiendo cuatro categorías empíricas: Reflexionando sobre la familia y el proceso Salud Enfermedad; la familia y sus conceptos actuales; el trabajo de la enfermera con las familias víctimas de violencia; y las conductas realizadas frente a los casos de violencia. Se concluye que las enfermeras reconocen las dificultades y facilidades en la atención de familias víctimas de violencia, expresaron impotencia para superarlas y perciben escasez de cursos preparatorios y capacitaciones que dificultan la actuación profesional frente a la temática. Se sugiere la capacitación de los profesionales a través de la educación permanente para reorganizar el proceso de trabajo, enfocando a las necesidades de las familias víctimas de violencia.

Violence is derived from conflicts of authority, power struggles, the will to dominate, the desire to destroy others and their assets. It is important to consider the impact that cases of violence have on health services. The goal was to identify the Basic Care nurses' perception of the phenomenon of domestic violence and their relation with the families. Thanks to a prospective, descriptive and exploratory study, made with a qualitative approach and based upon the "Práxica" theory of intervention of Collective Health nursing. Three analytical categories were proposed: the concept of family, the work process of the Basic Attention nurses and gender. Seven in-depth interviews were made to the nurses of the Basic Care Units in the metropolitan region of Sao Paulo. The Fiorin Discourse analysis technique was used, which resulted in four empirical categories: Reflection about families and the health-disease process; the family and its current concepts; the nurse's work with the families that are victims of violence and the position taken when faced to cases of violence. It was concluded that the nurses recognize the difficulties and simplicities in the attention of families that were victims of violence. They expressed their impotence to overcome the difficulties and they sense a lack of preparation and training courses related to this matter, which in turn makes professional performance rather difficult. It was also suggested that professional training through permanent education is the way to reorganize the work processes, focusing on the needs of the families that were victims of violence.

Aviolência decorre dos conflitos de autoridade, das lutas de poder, da vontade de domínio, do desejo de aniquilação dos outros e de seus bens. É importante considerar os impactos que os casos de violência têm na sociedade. O estudo teve como objetivo a identificação da percepção dos enfermeiros de Atenção Básica sobre o fenômeno da violência doméstica e sua relação com as famílias. Foi um estudo prospectivo, descritivo e exploratório, de abordagem qualitativa, e sustentada pela Teoria de Intervenção "Práxica" da Enfermagem de Saúde Coletiva. Foram propostas três categorias de análise: conceito de família, processo de trabalho do enfermeiro na Atenção Básica e gênero. Sete entrevistas em profundidade foram feitas a enfermeiras das Unidades Básicas de Saúde na região metropolitana de São Paulo. A técnica de Análise do Discurso de Fiorin foi utilizada, surgindo dela quatro categorias empíricas: Refletindo sobre a família e o processo Saúde-Doença; a família e seus conceitos atuais; o trabalho de enfermeira com as famílias das vítimas de violência, eles exprimiram sua impotência para ultrapassá-las e percebem uma carência de cursos de preparação e de capacitação que dificultam a ação profissional perante este tema. É sugerida a capacitação dos profissionais através da educação permanente para reorganizar o processo de trabalho, focalizado nas necessidades das famílias vítimas de violência.

Revestimentos refratários são severamente solicitados pela erosão causada por partículas que se movem pneumaticamente através de vasos e dutos em calcinadores de leito fluidizado. Esse tipo de desgaste constitui um fator chave para a degradação do revestimento desse equipamento. Consequentemente, o desempenho desses refratários tem um efeito imediato no lucro da empresa, uma vez que paradas para reparos tem um impacto direto no cronograma operacional e nos custos de manutenção da unidade produtiva. Apesar da temperatura de operação dos calcinadores variar entre 200 e 1250 ºC, a resistência a erosão, que é uma das principais propriedades selecionadas para avaliar materiais usados nessa aplicação, geralmente é medida somente à temperatura ambiente. Porém, esse tipo de avaliação não representa fielmente as condições de operação. Portanto, é necessário um estudo mais realista na tentativa de encontrar alguma relação entre a severidade de erosão e a temperatura. Visando alcançar esse objetivo, o presente trabalho apresenta o desenvolvimento e aplicação de um equipamento de erosão à quente para avaliação de concretos refratários para calcinadores de leito fluidizado.

Refractory linings are heavily damaged by the erosion caused by particles moving pneumatically through vessels and pipes in fluid flash calciners. This sort of wearing constitutes one of the key factors for equipment lining degradation. Consequently, the performance of materials has an immediate effect on a company's profit, as each maintenance call has a direct impact on the operational schedule and costs. Although the operation temperature of the calciners ranges from 200 up to 1250 ºC, the erosion resistance, which is one of the main properties selected to evaluate the materials used in this application, is mostly measured only at room temperature. Nevertheless, this sort of evaluation does not represent the actual working environment. Therefore, it is worth studying this subject in more depth in order to find out some relationship between the severity of erosion and the temperature. In order to reach this target, the present work comprises the development and application of hot erosion equipment concerning the evaluation of refractory castables for fluid flash calciners.

A literatura indica diversos tipos de ensaios e diferentes métodos de avaliação de dano por choque térmico. Adicionalmente sabe-se que, em determinadas aplicações, esse tipo de dano é um dos principais responsáveis pela degradação do revestimento refratário. Neste contexto e buscando a melhor forma de reproduzir as condições em serviço do revestimento refratário, o presente trabalho foi realizado visando analisar qual tipo de ensaio de choque térmico e método de avaliação do dano são os mais adequados para avaliar o desempenho destes materiais. Essa análise foi baseada em uma revisão bibliográfica e resultados obtidos em laboratório, em que se comparou e avaliou as vantagens e desvantagens dos métodos mais relevantes encontrados na literatura. Por fim, com o auxilio da ferramenta SWOT foi possível verificar se o método adotado pelos autores desse trabalho é adequado para auxiliar na seleção do refratário para aplicação em calcinadores de leito fluidizado.

The literature shows different tests and techniques for evaluating the thermal shock damage. Additionally, it is known that, for certain applications, this type of wear mechanism is one of the main causes of fluid flash calciner refractory degradation. Within this context and in order to find the best way to reproduce the refractory lining service conditions, this work was carried out to point out which thermal shock test and damage assessment method are more suitable to evaluate these materials. This analysis was based on a literature review and laboratory experiments, comparing and evaluating the advantages and disadvantages of the most important methods available. Finally, with the support of the SWOT tool it was possible to evaluate whether the method adopted by the authors of this work is appropriated for helping the selection of the refractories for calciners application.

A infecção por citomegalovírus em doentes com colite ulcerosa está descrita em menos de 50 casos, mas pode ter implicações clínicas. Enquanto alguns autores consideram o vírus uma causa de exacerbação da doença inflamatória, outros vêem-no como um mero achado. No entanto, o ganciclovir levou a remissão clínica em vários casos publicados. Os autores descrevem o caso de um homem de 42 anos, internado por diarreia, astenia e edema generalizado. Tratava-se de um alcoólico, sem outras patologias conhecidas, nem evidência laboratorial de imunossupressão. Uma fibrossigmoidoscopia revelou colite activa, com células com inclusões intranucleares. Iniciou-se ganciclovir, com melhoria clínica, mas as biopsias de controlo mostraram colite ulcerosa activa, sem evidência de citomegalovírus. Acrescentou-se à terapêutica mesalazina, com remissão completa do quadro.

Cytomegalovirus infection in patients with ulcerative colitis is described in fewer than 50 cases, but it may have clinical implications. While some authors pose the virus as a cause of exacerbations, others see it as a mere bystander. Nevertheless, ganciclovir therapy led to clinical remission in several published cases. We report the case of a 42-year-old male admitted for diarrhoea, asthenia and generalized oedema. He was an alcoholic, with no other known disease and no laboratorial evidence of immunosuppression. Flexible sigmoidoscopy revealed an active colitis with cells containing intranuclear inclusions. Ganciclovir therapy was started, with clinical improvement, but biopsies taken 7 days later showed active ulcerative colitis, with no evidence of cytomegalovirus. Mesalazine was added, with complete remission.

The objective of this work was to study enzyme immobilization on chitosan activated with glutaraldehyde, aiming to produce a cheap biocatalyst. Two different immobilization strategies were studied: one-point and multipoint covalent attachment to the solid matrix. The multipoint covalent attachment derivative had an 82% immobilization yield. It was 4.9-fold more stable than the free enzyme at 50°C and 4.5-fold more stable than soluble enzyme at pH 10.0. The one-point derivative had an 85% immobilization yield. It was 2.7-fold more stable than the free enzyme at 50°C and 3.8-fold more stable than soluble PGA at pH 10.0. Results indicated that chitosan can be loaded with PGA above 330 IU/g. Intraparticle diffusive effects, however, limited hydrolysis of penicillin G catalyzed by those derivatives at 37°C and 25°C. Operational stability assays were performed and the multipoint derivative exhibited a half-life of 40 hours.

The kinetic Ising model on an n-isotopic chain is considered in the framework of Glauber dynamics. The chain is composed of N segments with n sites, each one occupied by a different isotope. Due to the isotopic mass difference, the n spins in each segment have different relaxation times in the absence of interactions, and consequently the dynamics of the system is governed by multiple relaxation mechanisms. The solution is obtained in closed form for arbitrary n, by reducing the problem to a set of n coupled equations, and it is shown rigorously that the critical exponent z is equal to 2. Explicit results are obtained numerically for any temperature and it is also shown that the dynamic susceptibility satisfies the new scaling (Nagel scaling) proposed for glass-forming liquids. This is in agreement with our recent results (L. L. Gonçalves, M. López de Haro, J. Tagüeña-Martínez and R. B. Stinchcombe, Phys. Rev. Lett. 84 , 1507 (2000)), which relate this new scaling function to multiple relaxation processes.