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ACIDENTES DE TRABALHO EM HOSPITAL CENTRAL: UMA VISÃO HOLÍSTICA
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Miguel, S

; Garcia, M

; Cunha, A

Revista Portuguesa de Saúde Ocupacional online

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dec 2023, Volume 16 elocation esub0413

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução Em todo mundo os trabalhadores estão expostos a riscos no local de trabalho, podendo resultar em acidentes. Os hospitais são ambientes ricos em perigos e, por isso, com maior probabilidade de ocorrerem Acidentes de Trabalho com consequentes lesões músculo-esqueléticas ou com risco de transmissão de agentes biológicos. Objetivos Conhecer as caraterísticas dos acidentes em contexto laboral que ocorrem num Hospital Central. Ao descrever e analisar os mesmos, é possível fazer uma adequada avaliação de risco, permitindo no futuro adotar medidas preventivas que reduzam ou eliminem os perigos existentes em meio hospitalar. Materiais e métodos Estudo observacional, transversal, descritivo e analítico. Como instrumento de recolha foi utilizada uma base de dados existente no Serviço de Saúde Ocupacional de um Hospital Central, com informação relativa aos Profissionais de Saúde acidentados. Foram selecionados apenas os acidentes mecânicos ou com exposição a agentes biológicos. Foi testada a normalidade das distribuições e aplicados os testes do Qui Quadrado, Fisher ou Mann-Whitney, sendo considerado o nível de significância para rejeição da hipótese nula de 5%. Resultados Foram analisados um total de 265 Acidentes de Trabalho: 36.2% classificaram-se como mecânicos e os restantes como biológicos. Os grupos com maior número de sinistrados foram os Enfermeiros (49.4%) e com idades entre os 21 e os 30 anos (36.2%). De janeiro a março de 2021 registou-se o maior pico de acidentes (n=51) e o tempo mediano desde a admissão até a ocorrência de acidentes foi inferior nos que tiveram exposição a fluidos biológicos, comparativamente com os mecânicos. A atribuição de Incapacidade Temporária Absoluta aos sinistrados foi de 84.5%, destacando-se ainda que não existiram associações entre variáveis independentes e a atribuição de incapacidade temporária (absoluta ou parcial). Discussão e conclusões As características da população que sofreu Acidentes de Trabalho no Hospital Central em análise é idêntica à de outros estudos. Durante o pico de internamentos na pandemia COVID-19, o número de acidentes no Hospital aumentou, sugerindo que a pandemia e a elevada carga de trabalho associada podem ser uma possível causa. A elevada incidência de acidentes com exposição a fluidos biológicos, em profissionais com menos experiência, pode estar relacionada com a pouca destreza no manuseio de materiais e equipamentos e a elevada atribuição de Incapacidade Temporária Absoluta pode-se atribuir à baixa notificação de acidentes menos graves. Assim, o Serviço de Saúde Ocupacional deverá interceder junto dos Profissionais de Saúde para promover a notificação de acidentes, particularmente os menos graves que são frequentemente desvalorizados, permitindo tomar medidas para minimizar esses eventos. Será importante reforçar medidas preventivas que, considerando as características dos acidentes, poderão ser a utilização de equipamentos ou materiais para mobilização de cargas, utilização de calçado adequado, melhoria das infraestruturas do Hospital, sensibilização para os riscos existentes e, especialmente em acidentes com exposição a fluidos biológicos, formação para melhoria das capacidades técnicas dos profissionais no manuseio de materiais e equipamentos. Não foram identificados preditores para a existência de incapacidade temporária após Acidente de Trabalho, recomendam-se estudos com uma população-alvo maior, maior espaço temporal e, eventualmente, estudos longitudinais para identificar eventuais associações.

ABSTRACT Introduction All over the world, workers are exposed to hazards in the workplace, which can result in accidents. Hospitals are environments rich in dangers and, therefore, Work accidents are more likely to occur with subsequent musculoskeletal injuries, or risk of transmission of biological agents. Objectives To know the characteristics of accidents in the work context that occur in a Central Hospital. By describing and analyzing them, it is possible to make an adequate risk assessment, allowing in the future to adopt preventive measures that reduce or eliminate the existing dangers in the hospital environment. Materials and methods Observational, cross-sectional, descriptive and analytical study. As a data collection instrument, a database belonging to the Occupational Health Service of a Central Hospital, with information on injured Health Professionals, was used. Only mechanical accidents or those with exposure to biological fluids were selected. The normality of the distributions was tested and the Chi-Square, Fisher or Mann-Whitney tests were applied, considering the significance level for rejection of the null hypothesis of 5%. Results A total of 265 Work Accidents were analyzed, 36.2% mechanical and the remaining with exposure to biological fluids. The groups with the highest number of victims were the nurses (49.4%) and aged between 21 and 30 years (36.2%). Between January and March 2021 there was a peak in the number of accidents (n=51) and the median time from admission to the occurrence of the accident was lower in those who had exposure to biological fluids compared to mechanical ones. The attribution of Absolute Temporary Disability to the victims was 84.5%, highlighting that there were no associations between independent variables and the attribution of temporary disability (absolute or partial). Discussion and conclusions The characteristics of the population that suffered Work Accidents at the Central Hospital under analysis is identical to those of other studies. During the peak of hospitalizations in the COVID-19 pandemic, the number of accidents in the Hospital increased, suggesting that the pandemic and the associated high workload may be a possible cause. The high incidence of accidents with exposure to biological fluids, in professionals with less experience, may be related to the lack of dexterity in the handling of materials and equipment and the high attribution of Absolute Temporary Incapacity can be attributed to the low notification of less serious accidents. In this way, the Occupational Health Service should intercede with the Health Professionals to promote the notification of accidents, particularly the less serious ones that are often devalued, allowing to take measures to minimize these events. It will be important to strengthen preventive measures, which, considering the characteristics of accidents, may be the use of equipment or materials for the mobilization of loads, use of appropriate footwear, improvement of the Hospital's infrastructures, awareness of existing risks and, especially in accidents with exposure to biological fluids, training to improve the technical skills of professionals in the handling of materials and equipment. No predictors were identified for the existence of temporary disability after a Work Accident, studies with a larger target population, an increase in time span and, eventually, longitudinal studies to identify possible associations are recommended.

https://doi.org/10.31252/rpso.21.10.2023

The use of seawater in copper hydrometallurgical processing in Chile: A review
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Astudillo, Á.

; Garcia, M.

; Quezada, V.

; Valásquez, L.

Journal of the Southern African Institute of Mining and Metallurgy

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jul 2023, Volume 123 N. 7 Pages 357 - 364

Abstract: En | Text: En | PDF: En

Seawater has become a viable alternative for different uses in copper hydrometallurgy. In this paper we review the main physical and chemical characteristics of seawater and how these influence copper production. Reliable data on the use of continental water are reported, and the current use and consumption of seawater in the Chilean mining industry is analysed, indicating the main areas of use and the main problems encountered. Additionally, the influence of the elements in seawaterthat have the most influence on the extractive metallurgy of copper are considered. The Chilean copper mining industry currently consumes approximately 4.1 m³/s of seawater, which corresponds to 25% of the total water used. The use of seawater for the leaching of copper sulphide minerals, such as chalcopyrite, is beneficial because it provides 20 g/L of chloride, thereby improving copper dissolution kinetics.

https://doi.org/10.17159/2411-9717/2445/2023

Leptodelphax maculigera (Hemiptera: Delphacidae): first occurrence in Southern Brazil and potential rayadofino vector Hemiptera (Hemiptera Delphacidae Delphacidae)
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Bortolotto, O. C.

; Molina, R. O.

; Garcia, M. H.

; Pazini, J. B.

; Andrade, C. C. L.

; Mituti, T.

Brazilian Journal of Biology

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2023, Volume 83 elocation e277457

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/1519-6984.277457

Prevalencia de Dientamoeba fragilisy otros protozoários intestinales en porcinos de una granja en la región Andina de Colombia
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Sudrez, K. J.

; Garcia, M. J.

; Restrepo, E. Y.

; Campo, L. F.

; Galván-Diaz, A. L.

Revista de la Facultad de Medicina Veterinaria y de Zootecnia

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aug 2022, Volume 69 N. 2 Pages 129 - 142

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Dientamoeba fragilis is a protozoan that parasitizes the large intestine of humans and domestic animals. To date, some aspects regarding D. fragilis life cycle, including hosts, reservoirs, infection mechanism, among others, are not yet clear. Swine are considered natural hosts for this protozoan, therefore their close contact with humans promotes its zoonotic transmission. In Colombia there are no studies on the presence of D. fragilis in animal hosts, including pigs, and data about other intestinal protozoa are scarce. The objective was to determine the prevalence of intestinal protozoan, including D. fragilis, in pigs raised in a farm from a rural area of Medellin (Andean region of Colombia). Fecal samples from 70 pigs in prefattening stage were collected. Direct fecal smear examination, trichrome and modified Ziehl-Neelsen stain were used in the study. Univariate analysis (frequency distribution and central tendency measures) and bivariate analysis were used to explore risk factors. Dientamoeba fragilis was found in 13% of the evaluated fecal samples. Other parasites detected included: Entamoeba spp. (66%), Blastocystis spp. (64%), Balantioides coli (36%), Cryptosporidium spp. (36%), Iodamoeba butschlii (17%), coccidias (4%), and Giardia spp. (1,4%). This is the first report of D. fragilis in swine in Colombia, and the high prevalence of other pathogen protozoa was also observed, which corroborates the role of pigs as important reservoirs for human infections. Studies focused on the evaluation of both swine and swine-exposed farm workers should be done in order to know the dynamics of transmission of this parasite.

RESUMEN Dientamoeba fragilis es un protozoário que parasita el intestino grueso del hombre y animales domésticos. Hasta el momento, aún no son claros aspectos de su ciclo de vida, como el rango de hospedadores, reservorios, mecanismo de infección, entre otros. Se postula que el cerdo es un hospedador natural para este protozoario y que, debido a su cercanía con el humano, podría facilitar una transmisión zoonótica. En Colombia no existen a la fecha estudios sobre la presencia de D. fragilis en hospedadores animales, incluidos los cerdos, y los datos sobre la prevalencia de otros protozoarios intestinales en estos animales son escasos. El objetivo fue determinar la frecuencia de protozoarios intestinales, incluyendo D. fragilis, en cerdos de una granja tecnificada de una zona rural de Medellín (región Andina de Colombia). Se recolectaron muestras de materia fecal de 70 cerdos en etapa de preceba, que fueron evaluadas mediante examen directo, tinción tricrómica y Ziehl-Neelsen modificado. Se realizaron análisis univariados con medidas de frecuencia relativa y tendencia central y análisis bivariados para la exploración de factores de riesgo. Se detectó la presencia de D. fragilis en un 13% de las muestras y de otros parásitos como Entamoeba spp. (66%), Blastocystis spp. (64%), Balantioides coli (36%), Cryptosporidium spp. (36%), Iodamoeba butschlii (17%), coccidias (4%) y Giardia spp. (1,4%). En este primer reporte de D. fragilis en cerdos en Colombia se observó la alta prevalencia de otros protozoarios patógenos, lo que corrobora el papel de los cerdos como importantes reservorios de infecciones humanas. Estudios sobre la presencia de este protozoario tanto en cerdos como en el personal encargado de su manejo contribuirían al conocimiento sobre su dinámica de transmisión.

https://doi.org/10.15446/rfmvz.v69n2.103263 101 downloads

VACINAÇÃO CONTRA A GRIPE EM PROFISSIONAIS DE SAÚDE EM TEMPOS DE PANDEMIA COVID-19 - MOTIVAÇÕES E PERCEÇÃO DO RISCO
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Garcia, M

; Pereira, G

; Miguel, S

Revista Portuguesa de Saúde Ocupacional online

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dec 2021, Volume 12 Pages 48 - 61

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução Os profissionais de saúde são um grupo particularmente sensível ao vírus da gripe, uma vez que são potenciais recetores e transmissores, sendo que a vacinação dos mesmos é uma pedra basilar na prevenção em contexto hospitalar. Objetivos Conhecer qual o impacto que a pandemia COVID-19 teve na perceção de risco de contrair infeção pelo vírus Influenza e na motivação para a vacinação contra a gripe sazonal dos profissionais de saúde de um Hospital Central. Metodologia Utilizou-se uma metodologia quantitativa, do tipo observacional, analítico, transversal, realizado num processo de amostragem por conveniência. A amostra obtida é constituída por 212 profissionais de saúde de ambos os sexos, com idades compreendidas entre os 20 anos e os 66 anos. Os dados obtidos foram analisados com o programa informático Microsoft Excel. Resultados Após o tratamento e análise dos dados obtidos, observou-se que a taxa de adesão à vacinação tem aumentado desde 2013 tendo um crescimento significativo (até 50%) na época vacinal 2020-2021. Participaram no estudo 212 indivíduos, predominantemente do sexo feminino (82%), com idades entre os 36 e os 50 anos (38,7%), com tempo de trabalho na instituição de 1-5 anos (23,6%) e sem predominância de categoria profissional. A maioria dos participantes consideram ter um risco médio/baixo de contrair gripe sazonal (60,4%). As características sociodemográficas não tiveram influência na perceção de risco. A principal motivação para a vacinação contra a gripe sazonal foi o contexto de pandemia COVID-19 (66%), sobretudo nos profissionais que não se vacinam consistentemente. Apenas cerca de 39% dos participantes se vacina anualmente e a maioria (80,7%) pretende vacinar-se no futuro. Conclusões O contexto pandémico acentuou a adesão dos profissionais de saúde à vacinação contra a gripe sazonal, no entanto os números atuais ainda estão aquém do recomendado para o contexto hospitalar. Adicionalmente, a perceção do risco de contrair gripe sazonal entre os profissionais de saúde mantém-se demasiado baixa, o que provavelmente justifica a baixa taxa de adesão à vacinação. Assim, é importante continuar a implementar medidas para aumentar a adesão dos profissionais de saúde à vacinação contra a gripe sazonal.

Abstract Introduction Healthcare workers are a group particularly sensitive to the flu virus, as they are potential receptors and transmitters of the virus, and their vaccination is a cornerstone of prevention in the hospital context. Objectives To find out what impact the COVID-19 pandemic had on the perception of risk of contracting an infection by the Influenza virus and on the motivation for vaccination against seasonal flu by healthcare workers at a Central Hospital. Methodology We used a quantitative methodology, observational, analytical, cross-sectional, carried out in a convenience sampling process. The sample obtained consists of 212 healthcare workers of both sexes, aged between 20 and 66 years. The data obtained were analyzed using the computer program Microsoft Excel. Results After processing and analyzing the data obtained, it was observed that the rate of adherence to vaccination has increased since 2013 (up to 50%) in the 2020-2021 vaccination season. A total of 212 individuals participated in the study, predominantly female (82,1%), aged between 36 and 50 years (38.7%), working at the institution for 1-5 years (23.6%) and without predominance of professional category. The majority of participants consider having a medium/low risk of contracting seasonal flu (60.4%). Sociodemographic characteristics had no influence on risk perception. The main motivation for vaccination against seasonal flu was the context of the COVID-19 pandemic (66,0%), especially in professionals who do not get vaccinated consistently. Only about 39% of participants get vaccinated annually, and the majority (80.7%) plan to be vaccinated in the future. Conclusions The pandemic context accentuated the adherence of healthcare workers to vaccination against seasonal flu, however the current numbers are still below the recommended for the hospital context. Additionally, the perception of the risk of contracting seasonal flu among healthcare workers remains too low, which probably justifies the low rate of adherence to vaccination. Therefore, it is important to continue implementing measures to increase the adherence of healthcare workers to vaccination against seasonal flu.

https://doi.org/10.31252/rpso/11.12.2021 24 downloads

Influence of the host diet on the performance of Doryctobracon areolatus (Hymenoptera: Braconidae)
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Ongaratto, S.

; Pinto, K. J.

; Mânica-Berto, R.

; Nörnberg, S. D.

; Gonçalves, R. S.

; Garcia, M. S.

; Nava, D. E.

Brazilian Journal of Biology

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dec 2020, Volume 80 N. 4 Pages 727 - 734

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O custo adaptativo de parasitoides é geralmente influenciado pela qualidade do hospedeiro. Nós avaliamos parâmetros de desenvolvimento do parasitoide Doryctobracon areolatus (Hymenoptera: Braconidae) em larvas de Anastrepha fraterculus (Diptera: Tephritidae) criadas em dieta artificial com diferentes fontes proteicas. Larvas de A. fraterculus foram criadas em dietas a base de: 1) germe de trigo cru (testemunha); 2) farinha de arroz integral; 3) farinha de milho; e, 4) farinha de trigo integral + farelo de soja. As larvas foram usadas para o desenvolvimento de D. areolatus para avaliar o número de descendentes/fêmea, taxa de emergência, razão sexual, duração do período ovo-adulto, peso de adultos, comprimento da tíbia posterior e longevidade. Larvas de A. fraterculus criadas nas dietas a base de germe de trigo e farinha de milho, permitiram obter um maior número de descendentes do parasitoide, com menor duração do período de desenvolvimento ovo-adulto, para ambos os sexos. Nas dietas com farinha de arroz e farinha de milho, larvas de A. fraterculus geraram adultos de D. areolatus com maior peso e tamanho de tíbia de machos e fêmeas e uma maior quantidade de fêmeas. A dieta contendo farinha de trigo + farelo de soja afetou a geração de descendentes, causando uma menor razão sexual. As dietas a base de farinha de arroz e milho são as mais adequadas para a multiplicação do parasitoide.

Abstract Fitness in parasitoids is generally influenced by host quality. We evaluated the development parameters of Doryctobracon areolatus (Hymenoptera: Braconidae) parasitoid on Anastrepha fraterculus (Diptera: Tephritidae) larvae, reared in artificial diets with different protein sources. Larvae of A. fraterculus were reared in the diets based on 1) raw wheat germ (control); 2) whole rice flour; 3) corn flour; and, 4) whole wheat flour + soybean meal. The larvae were used for the development of D. areolatus, to evaluate the number of offspring/female, emergence rate, sex ratio, egg-adult period, adult weight posterior tibia length and longevity. Larvae of A. fraterculus reared in the diets based on wheat germ and corn flour obtained a greater number of offspring, with shorter duration of egg-adult period for males and females. In diets with rice flour and corn flour, A. fraterculus larvae generated adults of D. areolatus with greater weight, longer tibia length and higher sex ratio, whereas larvae reared in wheat flour + soybean meal diet had a lower sex ratio. The diets based on rice flour and corn are the most appropriate for multiplication of the parasitoid.

https://doi.org/10.1590/1519-6984.217968 574 downloads

Proceso de adaptación cultural del “Questionnaire for Assesing the Childbirth Experience (QACE)”
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Rodríguez Coll, P

; Casañas, R

; Collado Palomares, A

; Maldonado Aubian, G

; Vicente Garcia, M

; Escuriet Peiro, R

Enfermería Global

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2020, Volume 19 N. 60 Pages 289 - 321

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Background: Negative experiences during delivery are associated with women disempowerment, postpartum depression, post-traumatic stress disorder, and low breastfeeding rates. The Questionnaire for Assessing the Childbirth Experience (QACE) is a 23-item screening tool useful for discovering women with a negative experience in their birth process and avoids future complications in following pregnancies or couple's relationships. Objective: The general objective is to adapt the Questionnaire for Assessing the Childbirth Experience (QACE) to the Spanish population and to obtain its psychometric characteristics. Methodology: The cultural adaptation process consisted of forwarding translation and back translation into Spanish, conceptual equivalence evaluation by a committee of judges, comprehensibility evaluation and cognitive interview to a postpartum group. Psychometric characteristics were obtained throughout the factorial analysis, Kaiser-Meyer-Olkin (KMO) and Bartlett's test of sphericity and Cronbach alpha level. Results: After complete the adaptation process, the committee of judges made several adjustments to achieve a better comprehension in the Spanish population, avoid misunderstandings or offensive words in the target language. 138 participants were needed to calculate factor analysis. The KMO (0.838) and Bartlett test (p < 0.001) confirmed the adequacy of factor analysis and the Scree plot showed 6 factors with the predictive power of 73.75% supported total variance. Internal consistency was assured using a Cronbach α of 0.896. Conclusions: Data from this study demonstrate that the Spanish version of QACE is a valid and reliable measure of childbirth experience in the Spanish population.

RESUMEN Introducción: Las experiencias negativas durante el parto se han asociado con desempoderamiento de la mujer, depresión postparto, trastorno por estrés postraumático y bajas tasas de lactancia maternal, entre otros. El Questionnaire for Assessing the Childbirth Experience (QACE) es una herramienta de 23 ítems útil para identificar mujeres que han tenido una mala experiencia en su proceso de parto y evitar así futuras complicaciones en embarazos posteriores o en la relación de pareja. Objetivo: El objetivo general consiste en adaptar el Questionnaire for Assessing the Childbirth Experience (QACE) a la población española y obtener sus características psicométricas. Metodología: El proceso de adaptación cultural ha consistido en la traducción y retro traducción al español, evaluación de la equivalencia conceptual por un comité de jueces, evaluación de la comprensibilidad y una entrevista cognitiva a un grupo de mujeres puérperas. Las características psicométricas se han obtenido mediante el análisis factorial, los test de Kaiser-Meyer-Olkin (KMO) y Bartlett y el alfa de Cronbach. Resultados: Tras el proceso de adaptación transcultural, el grupo de expertos realizó las modificaciones necesarias para conseguir una mayor compresión del cuestionario en la población española, evitar malentendidos y palabras ofensivas en la lengua de destino. Se necesitaron 138 participantes para obtener el análisis factorial. El KMO (0,838) y el test de Bartlett (p < 0,001) confirmaron la adecuación del análisis factorial y el grafico de sedimentación mostró 6 factores con un poder predictivo del 73,75% del total de la varianza. La consistencia interna se obtuvo mediante un alfa de Cronbach de 0,896. Conclusiones: Los datos obtenidos en este estudio demuestran que la versión española del QACE es una herramienta válida y fiable para medir la experiencia en el nacimiento en la población española.

https://doi.org/10.6018/eglobal.402271 63 downloads

Sexto reporte de eventos adversos con tratamientos biológicos en Argentina: Informe del registro BIOBADASAR
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Gómez, G.

; Pons-Estel, G.

; Citera, G.

; Soriano, E.

; Saurit, V.

; Benavidez, F.

; Velozo, E.

; Dubinsky, D.

; Exeni, I.

; Gobi, C.

; Gómez, G.

; Díaz, M.

; Granel, A.

; Smichowsky, A.

; Garate, G.

; Quinteros, A.

; Cavillon, E.

; Petkovic, I.

; Larroude, M.S.

; de la Sota, M.

; Cappuccio, A.M.

; Berbotto, G.

; Alvarez, A.

; Papasidero, S.

; Lazaro, A.

; Garcia, M.

; Sacnun, M.

; Soares de Souza, S.

; Bertoli, A.

; Bejarano, V.

; Rillo, O.

; Kerzberg, E.

; Quintana, R.

; Agüero, S.

; Somma, L.

; Cruzat, V.

; Battaglitti, C.

; Perez Dávila, A.

; Gallardo, M.

; Pereira, D.

; Verando, M.

; Paira, S.

; Martinez, L.

; Aste, N.

; Pisoni, C.

; Catay, E.

; Graf, C.

; Casado, G.

; de la Vega, M.

Revista argentina de reumatología

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mar 2019, Volume 30 N. 1 Pages 4 - 9

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Objective: Update the results of the BIOBADASAR registry on safety, duration and causes of treatment interruption after 8 years of follow-up. Methods: BIOBADASAR is a safety record of biological therapies established by the Argentine Society of Rheumatology. The description of BIOBADASAR 3.0 is presented, a cohort of 53 centers in Argentina followed prospectively from August 2010 to January 2018. Results: 4656 patients were registered, 6234 treatments [3765 cases (therapy with biologicals) and 2469 controls (non-biological therapy)]. Treatment was interrupted in 44.6% in cases vs. 27.9% in controls. Main cause of discontinuation was due to inefficiency (40% cases vs. 32% controls). There were 3154 adverse events (2230 in cases vs. 924 in controls), of which 13.6% were tombs (9.8% in cases and 3.7% in controls). The most frequent adverse event (AE) in both groups were infections (43.56% in cases vs. 34.31% in controls, RR: 3.42, 95% CI: 3.02-3.88), and the upper airway pathways (14.5%). Neoplasms were published in 78 cases versus 45 controls (RR: 1.98, 95% CI: 1.37-2.86). Conclusions: In this article, there are no different trends regarding safety, duration and causes of interruption of treatment compared to previous reports. Infections were the main causes of treatment discontinuation. The advent of new biological agents and the need for control over long-term security, strengthens the use of this type of registration.

Objetivo: Actualizar los resultados del registro BIOBADASAR sobre seguridad, duración y causas de interrupción del tratamiento luego de 8 años de seguimiento. Métodos: BIOBADASAR es un registro de seguridad de terapias biológicas establecido por la Sociedad Argentina de Reumatología. Se presenta la descripción de BIOBADASAR 3.0, una cohorte compuesta por 53 centros de Argentina seguidos prospectivamente desde agosto de 2010 hasta enero de 2018. Resultados: Se registraron 4656 pacientes, 6234 tratamientos [3765 casos (terapia con biológicos) y 2469 controles (terapia no biológicos)]. Se interrumpió el tratamiento en el 44,6% en los casos vs. 27,9% en los controles. Causa principal de discontinuación fue por ineficacia (40% casos vs. 32% controles). Se presentaron 3154 eventos adversos (2230 en casos vs. 924 en controles), de los cuales el 13,6% fueron graves (9,8% en casos y 3,7% en controles). El evento adverso (EA) más frecuente en ambos grupos fueron las infecciones (43,56% en casos vs. 34,31% en los controles, RR: 3,42; IC 95%: 3,02-3,88), y de ellas las de vías aéreas superiores (14,5%). Las neoplasias se presentaron en 78 casos vs. 45 en controles (RR: 1,98; IC 95%: 1,37-2,86). Conclusiones: En este sexto reporte no se observan tendencias diferentes sobre seguridad, duración y causas de interrupción del tratamiento respecto a informes previos. Las infecciones fueron el principal EA y la ineficacia, seguido por EA y la pérdida de pacientes las principales causas de suspensión del tratamiento. El advenimiento de nuevos agentes biológicos y la necesidad de control en seguridad a largo plazo, fortalece el uso de este tipo de registro.

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Development and reprotuction of Spodoptera eridania on natural hosts and artificial diet
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Silva, A.

; Baronio, C. A.

; Galzer, E. C. W.

; Garcia, M. S.

; Botton, M.

Brazilian Journal of Biology

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jan 2019, Volume 79 N. 1 Pages 80 - 86

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O desenvolvimento e o potencial reprodutivo de Spodoptera eridania (Stoll, 1782) (Lepidoptera, Noctuidae) foi comparado em dietas naturais e artificial. A biologia de S. eridania foi determinada em condições de laboratório, comparando-se uma dieta artificial com folhas de trevo branco e de pêssego da cultivar 'Chimarrita' e frutos e folhas de maçã da cultivar 'Gala'. As larvas de S. eridania não puderam completar seu ciclo biológico quando alimentadas com frutas de maçã ou folhas de pêssego. A dieta artificial proporcionou o menor tempo de desenvolvimento, com um ciclo completo de 28,5 ± 0,14 dias de ovo a adulto e 37,3% de viabilidade total. As folhas de maçã levaram maior tempo de desenvolvimento de ovo a adulto (62,8 ± 1,22 dias) e menor viabilidade total (23%). O trevo branco apresentou a maior viabilidade total (54,3%). Os resultados mostraram que S. eridania pode usar trevo branco e folhas de maçã para se desenvolver normalmente em pomares de maçã. A redução de fontes alimentares, como o trevo branco usado pelas larvas, resulta em infestação e danos aos frutos através das “mordidas de prova”.

Abstract The development and reproductive potential of Spodoptera eridania (Stoll, 1782) (Lepidoptera, Noctuidae) was compared on natural and artificial diets. Its biology was determined under laboratory conditions, providing an artificial diet, leaves of white clover and the peach cultivar 'Chimarrita' and fruits and leaves of the apple cultivar 'Gala'. Larvae of S. eridania could not complete their biological cycle when fed on apple fruits or peach leaves. The artificial diet provided the shortest development time, with a cycle of 28.5±0.14 days from egg to adult and 37.3% total viability. Apple leaves led to a longer development time from egg to adult (62.8±1.22 days) and lower total viability (23%) and white clover provided the highest total viability (54.3%). The results showed that S. eridania can use white clover and apple leaves to develop normally in apple orchards. The reduction of food sources such as white clover used by the larvae results in infestation and damage to fruits from “test bites”.

https://doi.org/10.1590/1519-6984.177219 726 downloads

10.

Rearing two fruit flies pests on artificial diet with variable pH
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Dias, N. P.

; Nava, D. E.

; Smaniotto, G.

; Garcia, M. S.

; Valgas, R. A.

Brazilian Journal of Biology

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jan 2019, Volume 79 N. 1 Pages 104 - 110

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo As moscas-das-frutas (Diptera: Tephritidae) são consideradas as principais pragas da fruticultura mundial. No Brasil, duas espécies são predomindantes: a mosca-das-frutas Sul-americana, Anastrepha fraterculus e a mosca-do-Mediterrâneo, Ceratitis capitata. Neste estudo avaliamos o efeito de dietas artificiais com pH variável no seu desenvolvimento larval e performance de adultos. Os experimentos foram realizados em laboratório a 25 ± 2 °C, 70 ± 10% UR e fotoperíodo de 12:12 horas. Foram testadas dietas semi-sólidas com valores de pH de 6,0; 5,0; 4,0; 3,0; 2,0; 1,5 e 1,0, ajustados pela adição de ácido clorídrico. Os resultados indicaram que a dieta com pH 6,0 não suportou o desenvolvimento larval de ambas as espécies de mosca-das-frutas. As dietas com pH ácido não permitiram o desenvolvimento de ovos, larvas ou pupas e a reprodução de adultos de A. fraterculus. Para C. capitata o pH da dieta artificial exerceu maior influência do que para A. fraterculus nos parâmetros de duração e viabilidade do estágio larval, número de pupas, razão sexual e longevidade de machos.

Abstract Fruit flies (Diptera: Tephritidae) are considered the main fruit pests worldwide. In Brazil, two species are predominant: the South American fruit fly, Anastrepha fraterculus and the Mediterranean fruit fly, Ceratitis capitata. In this study, we evaluated the effect of artificial diets with variable pH in their larval development and adult performance. The experiments were carried out in the laboratory at 25 ± 2 °C, 70 ± 10% RH and 12:12h (L:D) photoperiod. Semisolid diets with pH values of 6.0, 5.0, 4.0, 3.0, 2.0, 1.5, and 1.0, adjusted by adding hydrochloric acid were tested. Results indicated that the diet with pH 6.0 did not support larval development of both species of fruit fly. Diets with greater acidic pH values did not allow egg, larvae or pupae development and adult reproduction of A. fraterculus. For C. capitata , the pH of artificial diet exerts greater influence compared to A. fraterculus on the duration and viability of the larval stage, number of pupae, sex ratio and longevity of males.

https://doi.org/10.1590/1519-6984.179347 1714 downloads

11.

Oviposition of fruit flies (Diptera: Tephritidae) and its relation with the pericarp of citrus fruits
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Dias, N. P.

; Nava, D. E.

; Garcia, M. S.

; Silva, F. F.

; Valgas, R. A.

Brazilian Journal of Biology

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dec 2018, Volume 78 N. 3 Pages 443 - 448

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo As moscas-das-frutas (Diptera: Tephritidae) representam um risco à fruticultura mundial, especialmente na cultura dos citros, entretanto estudos biológicos demonstram que as moscas-das-frutas não estão perfeitamente adaptadas à estes hospedeiros. Este estudo investigou a oviposição de Anastrepha fraterculus (Wiedemann, 1830) e Ceratitis capitata (Wiedemann, 1824) e sua relação com o pericarpo de frutos cítricos. Foi avaliada a relação entre a profundidade de oviposição de A. fraterculus e de C. capitata e a espessura do epicarpo dos frutos de laranjeira [Citrus sinensis (L.) Osbeck)] ‘Navelina’ e tangerineira [C. reticulata (L.)] ‘Clemenules’ e a influência do mesocarpo de frutos de tangerineira ‘Clemenules’ na oviposição destas espécies. O estudo foi conduzido em condições controladas de temperatura (25 ± 2 °C), umidade relativa (70 ± 10%) e fotofase (12 horas). A. fraterculus e C. capitata depositaram ovos no flavedo de frutos de laranjeira ‘Navelina’ e entre o flavedo e o albedo de frutos de tangerineira ‘Clemenules’. Quando oferecido frutos com mesocarpo exposto, não houve oviposição por ambas as espécies de mosca. Os resultados demonstram que a espessura do epicarpo de frutos cítricos não influenciou a oviposição de A. fraterculus e de C. capitata, a qual não ocorreu na presença apenas do mesocarpo, sugerindo que outros fatores estão envolvidos na oviposição por estas espécies.

Abstract Fruit flies (Diptera: Tephritidae) represent a threat to fruit growing worldwide, mainly the citrus culture, however, biological studies show that fruit flies are not perfectly adapted to this host. This study investigated oviposition of Anastrepha fraterculus (Wiedemann, 1830) and Ceratitis capitata (Wiedemann, 1824) and its relation with the pericarp of citrus fruits. We evaluated the relationship between depth of oviposition of A. fraterculus and C. capitata and epicarp thickness of orange [Citrus sinensis (L.) Osbeck)] ‘Navelina’ and tangerine [C. reticulata (L.)] ‘Clemenules’ and the influence of fruit mesocarp of tangerine ‘Clemenules’ on oviposition of these species. The study was conducted under controlled conditions of temperature (25 ± 2 °C), relative humidity (70 ± 10% RH) and photophase (12 h). A. fraterculus and C. capitata laid their eggs in the flavedo region of orange ‘Navelina’ and between the albedo and flavedo of tangerine ‘Clemenules’. When fruits with mesocarp exposed were offered, there was no oviposition by both fruit fly species. The results show that epicarp thickness of citrus fruits did not influence oviposition of A. fraterculus and C. capitata as oviposition did not occur only in the presence of the mesocarp, suggesting that other factors are involved in oviposition of these species.

https://doi.org/10.1590/1519-6984.167661 2446 downloads

12.

Evolución de los pesos y tasa de crecimiento de corderos provenientes de madres de baja condición corporal
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Sosa, J. L

; Leva, P. E

; Toffoli, G. D

; Fernandez, G. B

; Boggero, C

; Garcia, M. S

Fave. Sección ciencias agrarias

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jun 2018, Volume 17 N. 1 Pages 71 - 74

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

The objective of the trial was to evaluate the weight and growth of Pampinta lambs maintained at the foot of the mother with a differential feeding (Creep Feeding) with ewes of body condition 1, 1,5. The trial was carried out in units of the Faculty of Agricultural Sciences and Veterinary Sciences, 20 Pampinta sheep and 20 lambs born in the month of September of 2017. The feeding of the lambs was made under unrestricted natural lactation with differential feeding. During the night the lambs separated from their mothers were taken to the food court and received a ration of soy and corn mixture sprinkled with powdered milk. The results were analyzed by means of ANOVA for a completely randomized design. The variables birth weight (p = 0.0065) and growth rate (p = 0.039) were significantly different between sex, daily weight gain and weight at 45 days were not different between sex.

El objetivo del ensayo fue evaluar el peso y el crecimiento de corderos Pampinta mantenidos al pie de la madre con una alimentación diferencial (Creep Feeding) con ovejas de condición corporal entre 1 y 1,5. El ensayo se llevó a cabo en dependencias de la Facultad de Ciencias Agrarias y Ciencias Veterinarias de la UNL, se utilizaron 20 ovejas Pampinta y 20 corderos nacidos en el mes de septiembre del 2017. La alimentación de los corderos se realizó bajo lactancia natural no restringida con alimentación diferencial. Durante la noche los corderos separados de sus madres fueron conducidos al patio de comida y recibían una ración de mezcla de soja y maíz espolvoreados con leche en polvo. Los resultados fueron analizados mediante ANOVA para un diseño completamente aleatorizado. Las variables peso al nacer (p=0,0065) y tasa de crecimiento (p=0,039) fueron signifi cativamente diferentes entre sexo. La ganancia de peso diaria y el peso a los 45días no fueron diferentes entre sexo.

120 downloads

13.

Occurrence of ants (Hymenoptera: Formicidae) in Banisteriopsis laevifolia (A.Juss.) B.Gates (Malpighiaceae) in São Paulo State, Brazil
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Sebastiani, R.

; Fujihara, R. T.

; Garcia, M.

Brazilian Journal of Biology

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jul 2017, Volume 77 N. 3 Pages 662 - 663

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/1519-6984.03816 826 downloads

14.

Evaluación del bienestar en vacas en un sistema de ordeñe automatizado durante la época estival: Estudio de caso
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Leva, P. E

; Ghiano, J. E. J

; Toffoli, G. D

; Fernandez, G. B

; Sosa, J. L

; Garcia, M. S

; Taverna, M

; Walter, E

Fave. Sección ciencias agrarias

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jun 2017, Volume 16 N. 1 Pages 131 - 140

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Thirty-seven heifers were housed in a pen with access to a robotic dairy farm. They had shadows in the feeder and resting places. From 18:00 hs to 08:00 hs had access a pasture. Behavior was recorded weekly for 24 hours. Twice a week at 5 times the respiratory rate was observed individual production was recorded daily. Weekly dairy control was performed. Two dates blood collection were performed to evaluate the level of cortisol. The average respiratory rate was 70 rpm. Milk production was 28 l v-1 d-1. The present cortisol values between 10 and 48 ng ml-1. Animals destined to 25, 1 % and 26, 1 % eating and ruminating behaviors and only 0.7% respectively to drink. The results are preliminary; indicate the feasibility of introducing automated systems combined with stress mitigation methods.

Treinta y siete vaquillonas fueron alojadas en un corral con acceso a un tambo robotizado. Poseían sombras de red en el comedero y en los lugares de descanso. Desde las 18:00 hs hasta las 08:00 hs tenían acceso a una pastura. Se registró el comportamiento semanalmente durante 24 horas. Dos veces por semana en 5 horarios, se observó la frecuencia respiratoria. La producción individual se registró diariamente. Semanalmente se analizó la composición de la leche.En dos fechas se realizaron toma de sangre para evaluar el nivel de cortisol. La frecuencia respiratoria media fue de 70 ±12 rpm. La producción de leche fue de 28 ± 1,6 L v-1 d-1. El cortisol presento valores entre 10 y 48 ng ml-1. Los animales destinaron 25,1 % y 26,1 % a las conductas de comer y rumiar respectivamente y sólo 0,7% a beber. Los resultados preliminares indicarían la factibilidad de introducir sistemas robotizados combinados con métodos de mitigación del estrés.

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15.

Bienestar en vacas en el preparto durante el verano 2014 en el Departamento Castellanos: Estudio de caso
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LEVA, P

; TONEATTI, I. E

; STEGMAYER, M

; GHIANO, J

; TOFFOLI, G. D

; FERNANDEZ, G

; GARCIA, M. S

; SOSA, J. L

Fave. Sección ciencias agrarias

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jul 2016, Volume 15 N. 1

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

During the summer of 2014 it was carried out a case study in order to evaluate some physiological and behavioral prepartum and postpartum production in dairy cows of high genetic merit responses with access to artificial shades were used.. 24 cows in prepartum they stayed in a dry pen. The shadows were located in the rest area and food court. Body weight and body condition were evaluated at start and 30 days into the trial. The respiratory rate was held twice a week in three times a day. The behavior log once a week. Body weight and body condition gain during this period indicating adequate diet was combined with the provision of shade. The average respiratory rate was 60 rpm, indicating a high middle stress. The conduct of standing in the shadow was the most prevalent. Eating behavior are kept within normal values: 92 minutes. Milk production was between 30 and 35 l / d, normal setting. The temperature and humidity index remained above 72. In addition, during february the rains were above normal in the area, caused problems in floor pens.

Durante el verano del 2014 se llevó a cabo un estudio de caso con el objetivo de evaluar algunas respuestas fisiológicas y conductuales preparto y productivas postparto, en vacas lecheras de alto merito genético con acceso a sombras artificiales. Se utilizaron 24 vacas en preparto que se alojaron en un corral seco. Las sombras estaban ubicadas en el área de descanso y en el patio de comida. El peso corporal y la condición corporal fueron evaluadas al inicio y a los 30 días de comenzado el ensayo. La frecuencia respiratoria se midió dos veces por semana en tres momentos del día. El registro de comportamiento una vez a la semana. El peso corporal y condición corporal aumentaron durante este periodo indicando que la combinacion de dieta adecuada con la provisión de sombra fue favorable. La frecuencia respiratoria en promedio fue de 60 rpm, indicando un estrés medio alto. La conducta de parado a la sombra fue la de mayor prevalencia. La conducta de comer se mantuvo dentro de los valores considerados normales: 92 minutos. La producción lechera fue de entre 30 y 35 l/d, normal para el establecimiento. El índice de temperatura y humedad se mantuvo por encima de 72. Además, durante febrero las lluvias fueron superiores a las normales de la zona, ocasionado problemas de piso en los corrales.

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