RESUMO Na vegetação da caatinga a Cnidoscolus phyllacanthus, popularmente conhecida como favela ou faveleira, destaca-se por ser uma planta altamente resistente a seca e de alto teor nutricional, apresentando diversas aplicações. O objetivo deste trabalho foi avaliar a influência de diferentes períodos sazonais na composição química da semente da faveleira da região Seridó/RN. As sementes, separadas em 3 lotes por períodos sazonais diferentes (lote 1 - época chuvosa; lote 2 - estiagem inicial; lote 3 - estiagem prolongada), foram trituradas e analisadas quanto aos teores de umidade, cinzas, lipídios, proteínas e carboidratos. Verificou-se que as sementes da faveleira apresentaram predominância de lipídios e de proteínas. Na análise de umidade observou-se diferença significativa (p < 0,05) entre todos os lotes, o teor de cinzas foi significativamente (p < 0,05) menor no lote 1 (4,67 ± 0,18) quando comparado ao lote 3 (4,96 ± 0,08), na análise de proteínas o lote 3 (30,42 ± 1,63) apresentou o maior teor e diferiu significativamente (p < 0,05) dos demais. Quanto aos lipídios houve diferença significativa (p < 0,05) entre os lotes, sendo o lote 2 (21,57 ± 0,37) o que apresentou o menor teor. Em relação aos carboidratos também houve diferença significativa (p < 0,05) entre os lotes, sendo o lote 1 (14,37 ± 1,83) o de menor teor e o lote 2 (39,17 ± 0,52) o de maior. As diferenças observadas entre os lotes ocorreram, em virtude de as sementes terem sido colhidas em períodos sazonais diferentes. A partir dos dados encontrados é possível afirmar que o período sazonal influencia no valor nutritivo da semente da faveleira, devendo-se verificar as melhores formas de utilização de acordo com o período de colheita.

ABSTRACT Cnidoscolus phyllacanthus, popularly known as favela or faveleira, is a species of the caatinga vegetation highly resistant to drought, with high nutritional content, and having several uses. The objective of this work was to evaluate the influence of different seasons on the chemical composition of faveleira seeds in the region of Seridó/RN. The seeds collected in different seasons were separated into 3 lots (lot 1 - rainy season; lot 2 - initial dry season; lot 3 - prolonged dry season), ground, and analyzed for moisture, ash, lipids, protein, and carbohydrates. The chemical analysis the seeds showed predominance of lipids and proteins. The results showed that moisture was significant different (p < 0.05) between all the lots; the ash content in lot 1 was significantly (p < 0.05) lower (4.67 ± 0.18) than lot 3 (4.96 ± 0.08); and protein content was highest in lot 3 (30.42 ± 1.63) and significantly (p < 0.05) different from the others. There was a significant difference (p < 0.05) for lipids between the lots, with lot 2 showing the lowest content (21.57 ± 0.37). Significant difference (p < 0.05) was also found for carbohydrates between the lots, with lot 1 (14.37 ± 1.83) having the lowest content and lot 2 (39.17 ± 0.52) the highest content. The differences observed between the lots are attributed to the harvest of the seeds in different seasonal periods. The results show that the seasonal period influences the nutritional value of faveleira seeds, and that better forms of use need to be identified according to the period of harvesting.

ABSTRACT Chronic kidney disease (CKD) increases cardiovascular disease (CVD) risk development. However, the mechanisms of reduced kidney function with CVD risk are unclear. This study aimed to investigate the association between kidney function and Framingham risk score (FRS) in participants with traditional cardiovascular risk factors and normal estimated glomerular filtration rate (eGFR) > 60 mL/min/1.73 m² in an admixed population of Brazil. The participants were divided into three groups according to FRS: low risk group with 0% to <10%, moderate risk group with ≥10% to 20% and high risk group with >20%. The eGFR was calculated using Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI). Data from participants were collected by questionnaire, and blood and urine samples were collected to analyze biochemical markers. A total of 214 subjects aged 53±10 years old was collected. There were 77 individuals in low risk group, 59 in moderate risk group and 78 in high-risk group. Mean eGFRCKD-EPI was 89.39±15.05 mL/min/1.73 m² and 90.74±16.17 mL/min/1.73 m2 when race adjustment. The results indicated that there is an increasing the cardiovascular risk with a decreased of eGFR, conforming to a significant inverse correlation observed between eGFR and FRS with Spearman correlation (R²=-0.256, p<0.001; R²=-0.224, p=0.001, when adjusted for race). There was a statistically significant difference in eGFRCKD-EPI (p<0.001) and eGFRCKD-EPI with race adjustment (p=0.002) among risk groups. The data suggests that the reduction eGFR is associated with elevated FRS among Brazilian adults without CKD. Furthermore, the results suggest that race adjustment it’s not necessary in Brazilian population.