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ABSTRACT Effluent from fish farming with saline water is a source of water, also rich in organic matter and nutrients, that can be used in irrigation of cultivated plants and even fully or partially replace mineral fertilization. The objective was to evaluate the growth, biomass production and quality of P. maximum cultivars fertigated with fish farming effluent in a greenhouse experiment, using a randomized block design with eight replicates. Treatments were arranged in a split-split-plot scheme, with three irrigation managements in the plot (irrigation with public-supply water, irrigation with public-supply water + conventional fertilization, and irrigation with fish farming effluent), three cultivars of P. maximum (Tanzania, Mombasa, and Massai) in the sub-plot, and four cutting times in the sub-sub-plot (45, 90, 135, and 180 days after sowing). Plant height, number of tillers, production of fresh biomass, neutral detergent fiber, acid detergent fiber, ether extract, crude protein, dry matter, and mineral matter contents were analyzed. The highest growth, production, and quality of P. maximum grass occurs when irrigated with public-supply water and under conventional NPK fertilization. Fertigation with fish farming effluent reduces the growth and production of P. maximum grass, but allows obtaining better quality forage. It is possible to irrigate P. maximum grass using fish farming effluent with satisfactory yields. The growth of cv. Massai was more sensitive to irrigation with fish farming effluent than those of the cultivars Tanzania and Mombasa. nutrients fertilization P experiment replicates splitsplitplot split scheme publicsupply public supply effluent, , effluent) Tanzania, (Tanzania Mombasa subplot, subplot sub plot, sub-plot subsubplot 45, 45 (45 90 135 18 sowing. sowing . sowing) height tillers fiber extract protein analyzed forage yields cv 4 (4 9 13 1 (