ABSTRACT One of the most common dental procedures is tooth extraction; however, the bone defect resulting from the process is only partially restored, leading to considerable bone loss. To rehabilitate a fully or partially edentulous patient, we must handle these sites with delicate surgical procedures. There is a large literature presenting attempts to overcome the negative effects of a dental extraction, with the aim of reducing tissue volume loss or restoring the alveolar architecture. In this context, Partial Extraction Therapy (PET) represents a subgroup of interventions to prevent bone loss after extraction using the tooth itself to prevent alveolar bone loss. This literature review aims to make a survey of the published articles on PET, with an emphasis on socket shield technique, and to explain the other techniques such as root burial, pontic-shield and proximal socket-shield, their indications and counter indications in order to deepen the knowledge of these techniques. To identify the included or considered studies, we adopted a detailed search strategy for MEDLINE and Cochrane Library focused in the last 31 years, whose language was English, Spanish or Portuguese. This text presents an analysis of current data regarding the alternatives for alveolar preservation and the installation of immediate implants in these areas, presenting the possibility of a different surgical technique. However, due to the immaturity and lack of conclusive scientific evidence regarding the predictability of the procedures, it is considered that the use of the socket shield technique must be done in an extremely cautious way. however restored patient architecture context PET (PET burial ponticshield pontic socketshield, socketshield shield, socket-shield studies 3 years English Portuguese areas However way

RESUMO Um dos procedimentos odontológicos mais comuns é a extração dentária, contudo, , o defeito ósseo decorrente do processo é apenas parcialmente restaurado, levando a uma perda ossea volumétrica consideravel. Para reabilitar um paciente totalmente ou parcialmente desdentado, devemos manusear estes sitios com intervenções cirúrgicas delicadas. Há uma vasta literatura apresentando tentativas de transpor os efeitos negativos de uma extração dentária, com o objetivo de diminuir a perda volumétrica tecidual ou restaurar a arquitetura alveolar. Neste contexto, a Terapia de Extração Parcial (TEP) representa um subgrupo de intervenções para prevenir a perda óssea após exodontia, usando o próprio dente para prevenir a perda óssea alveolar. Essa revisão de literatura tem por objetivo fazer um levantamento dos artigos publicados sobre as TEP, com ênfase na técnica de socket shield, e explanar a cerca das demais técnicas como sepultamento radicular, pontic-shield e proximal socket-shield, suas indicações e contra-indicações, a fim de aprofundar o conhecimento dessas técnicas. Para a identificação dos estudos inclui?dos ou considerados, adotamos a estrate?gia de busca detalhada para os bancos MEDLINE e Biblioteca Cochrane nos u?ltimos 31 anos, cujo idioma fosse o ingle?s, espanhol ou o portugue?s. Este texto, apresenta uma análise de dados atuais a respeito das alternativas para a preservação alveolar e instalação de implantes imediatos nestas áreas, apresentando a possibilidade de uma técnica cirúrgica diferenciada. No entanto, devido a imaturidade e falta de comprovação cientifica contundente a respeito da previsibilidade dos procedimentos, considera-se que o emprego da técnica de socket shield deve ser feito de forma cautelosa. dentária contudo restaurado consideravel desdentado delicadas contexto TEP (TEP exodontia radicular ponticshield pontic socketshield, socketshield socket-shield contraindicações, contraindicações contra indicações, contra-indicações incluidos inclui considerados estrategia estrate gia ultimos u ltimos 3 anos ingles, ingles ingle s, s ingle?s portugues. portugues portugue s. portugue?s texto áreas diferenciada entanto considerase considera se cautelosa

RESUMEN Objetivos: mapear intervenciones de enfermería que capaciten al cuidador familiar de la persona con amputación de miembro inferior para su rol. Métodos: es una revisión de alcance guiada por la metodología del Instituto Joanna Briggs, llevada a cabo en diferentes bases de datos (incluyendo literatura gris). Resultados: se tuvieron en cuenta seis estudios publicados entre 2009 y 2021, a saber: intervenciones de asesoramiento y apoyo para pacientes y familiares; intervenciones de apoyo entre iguales realizadas por un par de profesionales certificados; participación de cuidadores o familiares en grupos de apoyo e intervenciones clave para el equilibrio psicológico del paciente y del cuidador familiar. Dos estudios analizaron la importancia de la formación del cuidador y del amputado y del desarrollo de habilidades de afrontamiento. Otro estudio recomendó intervenciones de apoyo informativo para los cuidadores en relación con el cuidado del amputado y su adaptación a la vida hogareña. Conclusiones: los resultados de esta revisión permiten identificar recomendaciones/directrices para la práctica y recomendaciones/sugerencias de intervenciones según las necesidades identificadas de los cuidadores familiares de pacientes con amputación de miembros inferiores. Objetivos rol Métodos Briggs incluyendo gris. gris . gris) Resultados 200 2021 saber certificados afrontamiento hogareña Conclusiones recomendacionesdirectrices recomendaciones directrices recomendacionessugerencias sugerencias inferiores 20 202 2

ABSTRACT Objectives: to map nursing interventions that empower the Family caregiver of the person with lower limb amputation for is role. Methods: scoping review guided by Joanna Briggs Institute methodology conducted in different databases (including gray literature). Results: six studies published between 2009 and 2021 were included. Interventions of counselling and support for patients and family; peer support interventions performed by a certified pair; involvement of caregivers or family members in support groups; and key interventions for patient and family caregiver psychological balance. Two studies discussed the importance of caregiver and amputee training and development of coping skills. Another study recommended Interventions of informative support for caregivers regarding care for the amputee and adaptation to home. Conclusions: results of this review allow the identification of recommendations (guidelines) for practice and recommendations/suggestions for interventions according with identified needs of family caregivers of patients with lower limb amputation. Objectives role Methods including literature. literature . literature) Results 200 202 included pair groups balance skills home Conclusions guidelines (guidelines recommendationssuggestions suggestions 20 2

RESUMO Objetivos: mapear intervenções de enfermagem que capacitem o cuidador familiar da pessoa com amputação de membro inferior para seu papel. Métodos: revisão de escopo orientada pela metodologia do Joanna Briggs Institute realizada em diferentes bases de dados (incluindo literatura cinzenta). Resultados: foram incluídos seis estudos publicados entre 2009 e 2021. Intervenções de aconselhamento e apoio para pacientes e familiares; intervenções de apoio de pares realizadas por uma dupla certificada; envolvimento de cuidadores ou membros da família em grupos de apoio; e intervenções-chave para o equilíbrio psicológico do paciente e do cuidador familiar. Dois estudos discutiram a importância do treinamento do cuidador e do amputado e do desenvolvimento de habilidades de enfrentamento. Outro estudo recomendou intervenções de suporte informativo para os cuidadores com relação aos cuidados com o amputado e à adaptação ao lar. Conclusões: os resultados dessa revisão permitem a identificação de recomendações (diretrizes) para a prática e recomendações/sugestões para intervenções de acordo com as necessidades identificadas dos cuidadores familiares de pacientes com amputação de membros inferiores. Objetivos papel Métodos incluindo cinzenta. cinzenta . cinzenta) Resultados 200 2021 certificada intervençõeschave chave enfrentamento lar Conclusões diretrizes (diretrizes recomendaçõessugestões sugestões inferiores 20 202 2

Abstract Objective to synthesize and analyze the scientific evidence on the structural empowerment of nurses, specifically in the context of the emergency room. Methods An integrative literature review was carried out using the electronic databases Lilacs, PubMed, Scopus, Web of Science and Embase. 174 articles were identified in the databases, considering the inclusion and exclusion criteria: original studies, in Portuguese, English and Spanish, published from 1996 onwards and whose scope was work on the structural empowerment of nurses working in the various emergency scenarios. After evaluating and refining the studies using the established criteria, a total of six studies were obtained for analysis. Results Two thematic categories were established to synthesize the knowledge: “the dimensions of structural empowerment of emergency nurses” and “the relationship between nurses’ structural empowerment and other variables and their impact in the emergency context”. These thematic categories made it clear that opportunity is fundamental to nurses’ empowerment in this context, as well as the relevance of leadership and the work environment as important components that influence nurses’ empowerment and professional practice. Conclusion Structural empowerment is significant for nurses’ professional practice in the context of emergencies, since having access to the dimensions of empowerment results in autonomy at work, higher levels of self-efficacy and an improvement in the quality and safety of the care provided. room Lilacs PubMed Scopus Embase 17 criteria Portuguese Spanish 199 scenarios analysis knowledge context. . context” emergencies selfefficacy self efficacy provided 1 19

Resumen Objetivo Sintetizar y analizar las evidencias científicas sobre el empoderamiento estructural de los enfermeros, específicamente en el contexto de emergencias. Métodos Revisión integradora de la literatura realizada en las bases de datos electrónicas Lilacs, PubMed, Scopus, Web of Science y Embase. Se identificaron 174 artículos en las bases de datos, con los siguientes criterios de inclusión y exclusión: estudios originales, en portugués, inglés y español, publicados a partir de 1996, cuyo alcance eran los trabajos sobre el empoderamiento estructural de enfermeros que trabajan en diferentes escenarios de emergencias. Después de la evaluación y la refinación de los trabajos mediante los criterios establecidos, se obtuvo un total de seis estudios para el análisis. Resultados Se establecieron dos categorías temáticas para sintetizar el conocimiento: “las dimensiones del empoderamiento estructural de los enfermeros de emergencias” y “la relación del empoderamiento estructural de los enfermeros con otras variables y el impacto en el contexto de emergencias”. Estas categorías temáticas permitieron evidenciar que la oportunidad es fundamental para el empoderamiento de los enfermeros en este contexto. Además, se observó la relevancia del liderazgo y del ambiente de trabajo como componentes importantes que influyen en el empoderamiento y en la práctica profesional de los enfermeros. Conclusión El empoderamiento estructural es significativo para la práctica profesional de los enfermeros en el contexto de emergencias, ya que tener acceso a las dimensiones del empoderamiento tiene como resultado la autonomía en el trabajo, mayores niveles de autoeficacia y una mejora de la calidad y seguridad de la atención brindada. emergencias Lilacs PubMed Scopus Embase 17 exclusión originales portugués español 1996 establecidos análisis conocimiento . Además brindada 1 199 19

Resumo Objetivo Sintetizar e analisar as evidências científicas acerca do empoderamento estrutural dos enfermeiros, especificamente no contexto da emergência. Métodos Revisão integrativa da literatura realizada nas bases de dados eletrônicas: Lilacs, PubMed, Scopus, Web of Science e Embase. Foram identificados 174 artigos nas bases de dados, considerando-se os critérios de inclusão e exclusão: estudos originais, nos idiomas português, inglês e espanhol, publicados a partir de 1996 e cujo escopo fossem os trabalhos acerca do empoderamento estrutural de enfermeiros atuantes nos diversos cenários da emergência. Após a avaliação e os refinamentos dos trabalhos por intermédio dos critérios estabelecidos, obteve-se um total de seis estudos para análise. Resultados Foram estabelecidas duas categorias temáticas para sintetizar o conhecimento: “as dimensões do empoderamento estrutural dos enfermeiros da emergência” e “a relação do empoderamento estrutural dos enfermeiros com outras variáveis e seu impacto no contexto da emergência”. Essas categorias temáticas permitiram evidenciar que a oportunidade é fundamental para o empoderamento do enfermeiro nesse contexto, além disso, observou-se a relevância da liderança e o ambiente de trabalho como componentes importantes que influenciam no empoderamento e na prática profissional do enfermeiro. Conclusão O empoderamento estrutural é significativo para prática profissional do enfermeiro no contexto da emergência, pois ter acesso às dimensões de empoderamento resulta em autonomia no trabalho, níveis maiores de autoeficácia e melhoria na qualidade e segurança da assistência prestada. emergência eletrônicas Lilacs PubMed Scopus Embase 17 considerandose considerando se exclusão originais português espanhol 199 estabelecidos obtevese obteve análise conhecimento . disso observouse observou prestada 1 19

Abstract Hyporthodus niveatus is an appreciated and valuable commercial fish species in the municipality of Niterói, state of Rio de Janeiro, Brazil, due its excellent quality flesh. The constant presence of helminths in the abdominal musculature, viscera and serosa of individuals of the species has been the subject of complaints among local fish traders because of economic losses due to their repugnant aspect. Considering their hygienic-sanitary importance and significance for collective health, the presence of helminths was investigated in 20 individual fish of H. niveatus purchased from fish markets in the municipality of Niterói in 2021-2022. Nematodes, identified as third-instar larvae of Contracaecum sp., Terranova sp., Hysterothylacium deardorffoverstreetorum and Raphidascaris sp., were found parasitizing the intestine and abdominal cavity. Acanthocephalans, identified as juveniles of Corynosoma australe, were found parasitizing the intestine. The highest parasitic indices were for H. deardorffoverstreetorum, with prevalence of 30%, mean intensity of 1.5, mean abundance of 0.45 and infection ranges of 1-2. Considerations about the zoonotic potential and hygienic-sanitary significance of these parasites are presented in order to increase food safety for consumers. Janeiro Brazil flesh musculature aspect hygienicsanitary hygienic sanitary health 2 H 20212022. 20212022 2021 2022. 2022 2021-2022 Nematodes thirdinstar third instar sp sp. cavity Acanthocephalans australe 30 30% 15 1 5 1.5 045 0 45 0.4 12. 12 2. 1-2 consumers 2021202 202 2021-202 3 1. 04 4 0. 1- 202120 2021-20 20212 2021-2 2021-

Abstract The University Pharmacy Program (FU), from the Federal University of Rio de Janeiro (UFRJ), was created based on the need to offer a curricular internship to students of the Undergraduate Course at the Faculty of Pharmacy. Currently, it is responsible for the care of about 200 patients/day, offering vacancies for curricular internships for students in the Pharmacy course, it has become a reference in the manipulation of many drugs neglected by the pharmaceutical industry and provides access to medicines for low-income users playing an important social function. Research is one of the pillars of FU-UFRJ and several master and doctoral students use the FU research laboratory in the development of dissertations and theses. As of 2002, the Pharmaceutical Care extension projects started to guarantee a rational and safe pharmacotherapy for the medicine users. From its beginning in 1982 until the current quarantine due to the COVID-19 pandemic, FU-UFRJ has been adapting to the new reality and continued to provide patient care services, maintaining its teaching, research, and extension activities. The FU plays a relevant social role in guaranteeing the low-income population access to special and neglected medicines, and to pharmaceutical and education services in health promotion. FU, , (FU) UFRJ, UFRJ (UFRJ) Currently 20 patientsday patients day patients/day course lowincome low income function FUUFRJ theses 2002 198 COVID19 COVID 19 COVID-1 pandemic teaching activities promotion (FU (UFRJ 2 COVID1 1 COVID-

Aim To evaluate dentin permeability after pretreatment with 2.5% aqueous solution of titanium tetrafluoride (TiF4), followed by a self-etching universal adhesive system. Methods Forty dentin discs (1.5 mm thick) were randomly divided into groups according to the application or non-application of a pretreatment, and the type of adhesive system to be tested (two-step self-etching/ Clearfil SE Bond/ Kuraray Medical, or universal adhesive system/ Single Bond Universal/ 3M ESPE). Both sides of the discs were conditioned with 37% phosphoric acid to remove the smear layer. The first hydraulic conductivity measurement (L1) was performed in a permeability machine, under 5 PSI pressure. The samples were sanded again to form a standardized smear layer. The teeth designated for pre-treatment with TiF4 received the TiF4 solutions applied actively for 60 seconds, and the adhesive systems were applied according to the manufacturer’s instructions. Then, a new hydraulic conductivity measurement (L2) was performed for the purpose of calculating the hydraulic conductance at a later time, considering the water viscosity and the thickness of the specimen. The percentage (L) of dentin permeability after application of the adhesive system was obtained (L (%) = [(L1-L2) x100] / L1). The Mann-Whitney non-parametric test was applied. Results There was no difference between the two adhesive systems, or between the groups with or without pretreatment, as regards dentin permeability (p>0.05). Conclusion Pretreatment with 2.5% TiF4 did not influence dentin permeability, irrespective of the adhesive system used. 25 2 2.5 TiF4, TiF , (TiF4) selfetching self etching 1.5 15 1 (1. thick nonapplication non twostep step selfetching/ etching/ Medical Universal M ESPE. ESPE . ESPE) 37 layer L1 L (L1 machine pressure pre treatment 6 seconds manufacturers manufacturer s instructions Then L2 (L2 time specimen % (% L1L2 LL [(L1-L2 x100 x L1. L1) MannWhitney Mann Whitney nonparametric parametric p>0.05. p005 p p>0.05 0 05 (p>0.05) used 2. (TiF4 1. (1 3 ( L1L [(L1-L x10 p00 p>0.0 (p>0.05 (TiF x1 p0 p>0. (p>0.0 p>0 (p>0. p> (p>0 (p> (p

Abstract Hydrogels are used for wound treatment, as they may contain one or more active components and protect the wound bed. Papain is one of the active substances that have been used with this purpose, alongside urea. In this paper, carboxypolymethylene hydrogels containing papain (2% and 10% concentrations) and urea (5% concentration) were produced. Physical-chemical stability was performed at 0, 7, 15 and 30 days at 2-8ºC, 25ºC and 40ºC, as well as the rheological aspects and proteolytic activity of papain by gel electrophoresis. Clinical efficacy of the formulations in patients with lower limb ulcers was also evaluated in a prospective, single-center, randomized, double-blind and comparative clinical trial. The results showed 7-day stability for the formulations under 25ºC, in addition to approximately 100% and 15% of protein activity for 10% and 2% papain hydrogel, respectively. The rheological profile was non-Newtonian for the 10% papain hydrogel tested. There were no significant differences regarding the mean time for healing of the lesions, although 10% papain presented a better approach to be used in all types of tissue present in the wound bed. treatment bed purpose paper 2 (2 10 concentrations 5% 5 (5 concentration produced Physicalchemical Physical chemical 0 7 1 3 28ºC, 28ºC ºC 8ºC, 8ºC 2-8ºC 40ºC electrophoresis prospective singlecenter, singlecenter single center, center single-center randomized doubleblind double blind trial 7day day 100 respectively nonNewtonian non Newtonian tested lesions (

ABSTRACT Introduction The human immunodeficiency virus (HIV) pandemic remains an important issue. In 2020, approximately 37.7 million people were living with the disease and there were more than 680 thousand deaths due to complications linked to the disease. Despite these exorbitant numbers, the introduction of highly active antiretroviral therapy has marked a new era, changing the epidemiological profile of the infection and related pathologies, including neoplasms. Objective We performed a literature review to assess the role of neoplasms in patients with HIV after the introduction of antiretroviral therapy. Methods A literature review was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method, searching the MEDLINE, LILACS, and COCHRANE databases for articles published from 2010 onwards. Results Using specific key terms, 1,341 articles were identified; two were duplicates, 107 were selected for full-text evaluation, and 20 were included in the meta-analysis. The selected studies included 2,605,869 patients. Fifteen of the 20 articles indicated a reduction in the global incidence of AIDS-defining neoplasms and 12 indicated an overall increase in non-AIDS-defining cancers after the introduction of antiretrovirals. This growth trend could be explained by a range of factors including the aging population with HIV, risky behaviors, and coinfection with oncogenic viruses. Conclusions There was a decreasing trend in the incidence of AIDS-defining neoplasms and increasing trend in non-AIDS-defining neoplasms. However, the carcinogenic effect of antiretrovirals could not be confirmed. In addition, studies focusing on the oncogenic role of HIV and screening for neoplasms in individuals with HIV are required. (HIV issue 2020 377 37 7 37. 68 numbers era pathologies MetaAnalyses Meta Analyses PRISMA (PRISMA method MEDLINE LILACS 201 onwards terms 1341 1 341 1,34 identified duplicates 10 fulltext full text evaluation 2 metaanalysis. metaanalysis meta analysis. analysis meta-analysis 2605869 605 869 2,605,86 AIDSdefining AIDS defining nonAIDSdefining non behaviors viruses However confirmed addition required 202 3 6 134 34 1,3 260586 60 86 2,605,8 13 1, 26058 8 2,605, 2605 2,605 260 2,60 26 2,6 2,

RESUMEN Objetivos: describir la percepción de los enfermeros acerca de la influencia de la supervisión clínica en la mejoría de los indicadores de calidad en la atención de enfermería. Métodos: investigación exploratoria de enfoque calitativo, realizada con 16 enfermeros utilizando el focus group. El procesamiento de datos emergió del análisis textual lexicográfico, recurriendo a la Clasificación Jerárquica Descendiente y análisis de similitud. Resultados: retención de 80,0% de 185 segmentos de texto con construcción de seis clases. Las palabras fueron representadas por cuatro grafos (supervisor, auditoría, cuidado y proceso); y tres subgrafos (implementación, partición y conocimiento). Consideraciones Finales: en la percepción de los enfermeros, la supervisión influencia los indicadores de calidad en la atención de enfermería. Objetivos enfermería Métodos calitativo 1 group lexicográfico similitud Resultados 800 80 0 80,0 18 clases supervisor, supervisor (supervisor auditoría proceso proceso) implementación, implementación (implementación conocimiento. conocimiento . conocimiento) Finales 8 80,

ABSTRACT Objectives: to describe nurses’ perception of the influence of clinical supervision on improving quality indicators in nursing care. Methods: exploratory research with a qualitative approach, carried out with 16 nurses using the focus group. Data processing emerged from lexicographical textual analysis, resorting to Descending Hierarchical Classification and similarity analysis. Results: 80.0% retention of 185 text segments with six-class construction. The words were represented by four graphs (supervisor, audit, care, and process); and three subgraphs (implementation, sharing and knowledge). Final Considerations: in the perception of nurses, supervision influences quality indicators in nursing care. Objectives care Methods approach 1 group analysis Results 800 80 0 80.0 18 sixclass six class construction supervisor, supervisor (supervisor audit process process) implementation, implementation (implementation knowledge. knowledge . knowledge) Considerations 8 80.

RESUMO Objetivos: descrever a percepção dos enfermeiros acerca da influência da supervisão clínica na melhoria dos indicadores de qualidade na assistência de enfermagem. Métodos: pesquisa exploratória de abordagem qualitativa, realizada com 16 enfermeiros utilizando o focus group. O processamento de dados emergiu da análise textual lexicográfica, recorrendo à Classificação Hierárquica Descendente e análise de similitude. Resultados: retenção de 80,0% de 185 segmentos de texto com construção de seis classes. As palavras foram representadas por quatro grafos (supervisor, auditoria, cuidado e processo); e três subgrafos (implementação, partilha e conhecimento). Considerações Finais: na percepção dos enfermeiros, a supervisão influencia os indicadores de qualidade na assistência de enfermagem. Objetivos enfermagem Métodos qualitativa 1 group lexicográfica similitude Resultados 800 80 0 80,0 18 classes supervisor, supervisor (supervisor auditoria processo processo) implementação, implementação (implementação conhecimento. conhecimento . conhecimento) Finais 8 80,

RESUMEN Objetivos: comparar la prevalencia de lactancia materna exclusiva versus alimentación artificial en recién nacidos de madres con COVID-19. Métodos: revisión sistemática de prevalencia, según JBI. Búsquedas en las bases de datos PubMed®, Embase, CINAHL, LILACS y Web of Science™ en agosto de 2021. Se seleccionaron estudios transversales, longitudinales o de cohortes, sin limitaciones de idioma y tiempo que mostraran prevalencia de lactancia materna o que permitieran calcular. Resultados: se analizaron 15 artículos publicados en 2020 y 2021, de cohorte (60%) o transversal (40%). El promedio de lactancia materna exclusiva en madres con COVID-19 fue 56,76% (IC=39,90-72,88), y lactancia artificial, 43,23% (IC = 30,99 – 55,88), sin diferencias estadísticamente significativas. Conclusiones: a pesar de las recomendaciones de mantener la lactancia materna, hubo una reducción a nivel mundial, en comparación con períodos previos a la pandemia. Con los avances de la ciencia, estas tasas han mejorado, mostrando el impacto de la evidencia en las prácticas. Como limitaciones se citan las fuentes del estudio. Se recomienda realizar nuevos estudios. Registro PROSPERO CRD42021234486. Objetivos COVID19. COVID19 COVID 19. 19 Métodos JBI PubMed PubMed® Embase CINAHL Science 2021 transversales cohortes calcular Resultados 1 202 60% 60 (60% 40%. 40 40% . (40%) COVID-1 5676 56 76 56,76 IC=39,9072,88, IC39907288 IC IC=39,90 72,88 , 39 90 72 88 (IC=39,90-72,88) 4323 43 23 43,23 3099 30 99 30,9 55,88, 5588 55,88 55 55,88) significativas Conclusiones mundial pandemia ciencia mejorado prácticas estudio CRD42021234486 CRD COVID1 20 6 (60 4 (40% COVID- 567 5 7 56,7 9072 IC=39,9072,88 IC3990728 IC3990 IC=39,9 7288 72,8 3 9 8 (IC=39,90-72,88 432 2 43,2 309 30, 558 55,8 CRD4202123448 (6 (40 56, 907 IC=39,9072,8 IC399072 IC399 IC=39, 728 72, (IC=39,90-72,8 43, 55, CRD420212344 ( (4 IC=39,9072, IC39907 IC39 IC=39 (IC=39,90-72, CRD42021234 IC=39,9072 IC3 IC=3 (IC=39,90-72 CRD4202123 IC=39,907 IC= (IC=39,90-7 CRD420212 (IC=39,90- CRD42021 (IC=39,90 CRD4202 (IC=39,9 CRD420 (IC=39, CRD42 (IC=39 CRD4 (IC=3 (IC=

ABSTRACT Objectives: to compare exclusive breastfeeding prevalence versus artificial feeding in newborns of mothers with COVID-19. Methods: a systematic review of prevalence, according to JBI. Searches in PubMed®, Embase, CINAHL, LILACS and Web of Science™ databases in August 2021. Cross-sectional, longitudinal or cohort studies were selected, without language and time limitations that showed breastfeeding prevalence or that allowed calculation. Results: fifteen articles published in 2020 and 2021, cohort (60%) or cross-sectional (40%) were analyzed. The average of exclusive breastfeeding in mothers with COVID-19 was 56.76% (CI=39.90–72.88), and artificial breastfeeding, 43.23% (CI = 30.99 – 55.88), without statistically significant differences. Conclusions: despite the recommendations for maintaining breastfeeding, there was a reduction worldwide, when compared to periods prior to the pandemic. With advances in science, these rates have improved, showing the impact of evidence on practices. As limitations, study sources are cited. It is recommended to carry out new studies. PROSPERO registration CRD42021234486. Objectives COVID19. COVID19 COVID 19. 19 Methods JBI PubMed PubMed® Embase CINAHL Science 2021 Crosssectional, Crosssectional Cross sectional, sectional Cross-sectional selected calculation Results 202 60% 60 (60% crosssectional cross 40% 40 (40% analyzed COVID-1 5676 56 76 56.76 CI=39.90–72.88, CI39907288 CI CI=39.90–72.88 , 39 90 72 88 (CI=39.90–72.88) 4323 43 23 43.23 3099 30 99 30.9 55.88, 5588 55.88 55 55.88) differences Conclusions worldwide pandemic science improved practices cited CRD42021234486 CRD COVID1 1 20 6 (60 4 (40 COVID- 567 5 7 56.7 CI3990728 CI=39.90–72.8 3 9 8 (CI=39.90–72.88 432 2 43.2 309 30. 558 55.8 CRD4202123448 (6 (4 56. CI399072 CI=39.90–72. (CI=39.90–72.8 43. 55. CRD420212344 ( CI39907 CI=39.90–72 (CI=39.90–72. CRD42021234 CI3990 CI=39.90–7 (CI=39.90–72 CRD4202123 CI399 CI=39.90– (CI=39.90–7 CRD420212 CI39 CI=39.90 (CI=39.90– CRD42021 CI3 CI=39.9 (CI=39.90 CRD4202 CI=39. (CI=39.9 CRD420 CI=39 (CI=39. CRD42 CI=3 (CI=39 CRD4 CI= (CI=3 (CI=

RESUMO Objetivos: comparar as prevalências de aleitamento materno exclusivo versus aleitamento artificial em recém-nascidos de mães com COVID-19. Métodos: revisão sistemática de prevalência, segundo JBI. Buscas nas bases PubMed®, Embase, CINAHL, LILACS e Web of Science™ em agosto de 2021. Selecionados estudos transversais, longitudinais ou coortes, sem limitação de idioma e tempo que apresentavam prevalência de aleitamento materno ou que permitissem o cálculo. Resultados: 15 artigos publicados em 2020 e 2021, coortes (60%) ou transversais (40%) foram analisados. A média de aleitamento materno exclusivo em mães com COVID-19 foi 56,76% (IC=39,90–72,88), e artificial, de 43,23% (IC = 30,99 – 55,88), sem diferenças estatisticamente significantes. Conclusões: apesar das recomendações para a manutenção do aleitamento materno, houve redução mundialmente, quando comparados à períodos anteriores à pandemia. Com avanços da ciência, esses índices têm melhorado, mostrando o impacto das evidências nas práticas. Como limitações, citam-se fontes dos estudos. Recomenda-se realização de novos estudos. Registro PROSPERO CRD42021234486. Objetivos recémnascidos recém nascidos COVID19. COVID19 COVID 19. 19 Métodos JBI PubMed PubMed® Embase CINAHL Science 2021 cálculo Resultados 1 202 60% 60 (60% 40% 40 (40% analisados COVID-1 5676 56 76 56,76 IC=39,90–72,88, IC39907288 IC IC=39,90–72,88 , 39 90 72 88 (IC=39,90–72,88) 4323 43 23 43,23 3099 30 99 30,9 55,88, 5588 55,88 55 55,88) significantes Conclusões mundialmente pandemia ciência melhorado práticas limitações citamse citam se Recomendase Recomenda CRD42021234486 CRD COVID1 20 6 (60 4 (40 COVID- 567 5 7 56,7 IC3990728 IC=39,90–72,8 3 9 8 (IC=39,90–72,88 432 2 43,2 309 30, 558 55,8 CRD4202123448 (6 (4 56, IC399072 IC=39,90–72, (IC=39,90–72,8 43, 55, CRD420212344 ( IC39907 IC=39,90–72 (IC=39,90–72, CRD42021234 IC3990 IC=39,90–7 (IC=39,90–72 CRD4202123 IC399 IC=39,90– (IC=39,90–7 CRD420212 IC39 IC=39,90 (IC=39,90– CRD42021 IC3 IC=39,9 (IC=39,90 CRD4202 IC=39, (IC=39,9 CRD420 IC=39 (IC=39, CRD42 IC=3 (IC=39 CRD4 IC= (IC=3 (IC=

RESUMEN Objetivo: Identificar las estrategias de supervisión que los estudiantes de Enfermería consideran facilitadoras del desarrollo de las capacidades de pensamiento crítico en el contexto de enseñanza clínica. Métodos: Estudio de naturaleza cualitativa, inserido en el paradigma interpretativo, con recurso a la metodología focus group. Participaron del estudio ocho estudiantes del curso de licenciatura en Enfermería. Resultados: Los participantes reconocieron la imprescindibilidad del pensamiento crítico para la responsabilidad profesional y calidad en la asistencia; y destacaron la importancia de la utilización de estrategias de supervisión adecuadas a sus necesidades, a los objetivos de aprendizaje y al contexto de la práctica clínica. Consideraciones finales: Este estudio sobrepasa la urgencia en establecerse, dentro de los currículos del curso de Enfermería, estrategias de supervisión clínica promotoras del pensamiento crítico, que favorezcan el desarrollo de capacidades para el bueno juicio clínico, resolución de problemas y toma de decisión segura, eficaz y ética. Objetivo Métodos cualitativa interpretativo group Resultados asistencia necesidades finales establecerse clínico segura ética

ABSTRACT Objective: To identify the supervisory strategies that Nursing students consider facilitators of the development of critical thinking skills in clinical teaching. Methods: This is a qualitative study, within the interpretative paradigm, using the focus group methodology. Eight undergraduate nursing students participated in the study. Results: Participants recognized the indispensability of critical thinking for professional responsibility and quality of care and highlighted the importance of using supervisory strategies adapted to their needs, learning objectives, and the context of clinical practice. Final considerations: This study highlights the urgent need to establish, within the Nursing curricula, clinical supervision strategies that promote critical thinking and favor the development of skills for good clinical judgment, problem solving, and safe, effective, and ethical decision-making. Objective teaching Methods paradigm methodology Results needs objectives practice considerations establish curricula judgment solving safe effective decisionmaking. decisionmaking decision making. making decision-making

RESUMO Objetivo: Identificar as estratégias supervisivas que os estudantes de Enfermagem consideram facilitadoras do desenvolvimento das capacidades de pensamento crítico no contexto de ensino clínico. Métodos: Estudo de natureza qualitativa, inserido no paradigma interpretativo, com recurso à metodologia focus group. Participaram do estudo oito estudantes do curso de licenciatura em Enfermagem. Resultados: Os participantes reconheceram a imprescindibilidade do pensamento crítico para a responsabilidade profissional e qualidade na assistência; e destacaram a importância da utilização de estratégias supervisivas adequadas às suas necessidades, aos objetivos de aprendizagem e ao contexto da prática clínica. Considerações finais: Este estudo sobreleva a premência em se estabelecer, dentro dos currículos do curso de Enfermagem, estratégias de supervisão clínica promotoras do pensamento crítico, que favoreçam o desenvolvimento de capacidades para o bom julgamento clínico, resolução de problemas e tomada de decisão segura, eficaz e ética. Objetivo clínico Métodos qualitativa interpretativo group Resultados assistência necessidades finais estabelecer segura ética

Abstract The objective of this paper was to develop and evaluate two semi-solid pharmaceutical forms containing 0.1% tacrolimus: cream (CRT01) and gel (GLT01). For the evaluation of physicochemical stability, at times 0, 30, 60 and 90 days, at 23°C and at 40°C, High Performance Liquid Chromatography coupled with a Diode Array Detector (HPLC-DAD) was employed. This method was developed and validated for tacrolimus quantification. The occlusivity test and skin permeation assay were also performed, using an animal model (Wistar rats), and the CRT01 and GLT01 were compared to the 0.1% tacrolimus ointment (PFU01) obtained from the University Pharmacy, Federal University of Rio de Janeiro, Brazil. CRT01 and GLT01 presented a homogeneous aspect and consistency adequate for topical products, along with sensory characteristics above PFU01. They also presented adequate physicochemical stability for 90 days and a lower occlusive effect than PFU01 (p<0.05). CRT01 showed greater affinity for the skin when compared to PFU01 and GLT01, with low systemic absorption. The CRT01 semi-solid formulation was considered the most adequate one to treat patients with atopic dermatitis or other dermatologic inflammatory diseases, promoting rational use of tacrolimus. semisolid semi solid 01 0 1 0.1 CRT (CRT01 GLT01. GLT . (GLT01) 30 6 9 23C C 23 40C 40 40°C HPLCDAD HPLC DAD (HPLC-DAD employed quantification performed Wistar rats, rats , rats) CRT0 GLT0 PFU (PFU01 Pharmacy Janeiro Brazil products PFU0 p<0.05. p005 p p<0.05 05 (p<0.05) absorption diseases 0. (CRT0 (GLT01 3 2 4 (PFU0 p00 p<0.0 (p<0.05 (CRT (GLT0 (PFU p0 p<0. (p<0.0 (GLT p<0 (p<0. p< (p<0 (p< (p

Abstract Oil-in-water photoprotective nanoemulsions (NEs) were developed using Babassu (BBS) lipophilic extract, nonionic surfactants, and low concentrations of organic sunscreens by ultrasonic processing. BBS extract was chosen due to its suitable physicochemical properties (acidity index, peroxide index, refraction index, and relative density) and predominance of saturated fatty acids, identified by gas chromatography-mass spectrometry (GC-MS), which promote biological activities and high oxidative stability. NEs were characterized by mean droplet size, morphology, polydispersity index (PdI), pH, and organoleptic properties, and the physical stability of the NEs was evaluated for 120 days at room temperature. The sun protection factor (SPF) was determined, and the photostability and in vitro cytotoxicity assays were performed for NEs. All NEs remained stable for 120 days, with a droplet size <150 nm and a monomodal distribution profile. The pH values were compatible with the skin’s pH. NE3 showed a spherical morphology, with a mean droplet size of 125.15 ± 0.16 nm and PdI of 0.145 ± 0.032. NE3 containing BBS extract and sunscreens presented an SPF of 35.5 ± 3.0, was photostable after 6 h of radiation and was non-cytotoxic to fibroblast cells. Thus, NE3 could be considered a promising formulation for developing synergic plant-extract sunscreen photoprotective products for the market. Oilinwater Oil water (NEs (BBS surfactants processing acidity density acids chromatographymass chromatography mass GCMS, GCMS GC MS , (GC-MS) morphology PdI, (PdI) 12 temperature (SPF determined 150 <15 profile skins skin s NE 12515 125 15 125.1 016 0 16 0.1 0145 145 0.14 0032 032 0.032 355 35 5 35. 30 3 3.0 noncytotoxic non cytotoxic cells Thus plantextract plant market (GC-MS (PdI 1 <1 1251 125. 01 0. 014 14 003 03 0.03 3. < 00 0.0

Resumen Este artículo parte de la investigación como práctica en movimiento, en la composición de territorios del acto de investigar como experiencia. Inspirándonos en la fuerza disruptiva de torsión-retorsión de los Tornillos (juerga de Sergipe, derivada de prácticas de resistencia a la esclavitud de los negros), proponemos un método de pensamiento para inventar formas de ver, decir y narrar a partir de lo que nos rodea, una posición en relación con el mundo y con él mismo, el cual constituye la idea de que este mundo no es un hecho, sino un efecto de nuestras prácticas. Desde esta perspectiva, pretendemos cuestionar las prácticas discursivas y no discursivas de la Psicología en favor de abrir caminos, en las cuales este conocimiento pueda refundar su propia historia, acentuando sus discontinuidades y heterogeneidades y, así, una actitud de hacer ante las prácticas colonialistas, ahora desde una perspectiva neoliberal. Este modo de investigación se realiza mediante: el funcionamiento de un método-idea de escritura genealógica, cartográfica y polifónica; la producción de máquinas de guerra nómadas, minoritarias y posidentitarias; y la composición con el tema que nos rodea a favor del conocimiento y las redes locales que no puede ser domesticada, como el árbol mangabeira. movimiento experiencia torsiónretorsión torsión retorsión juerga Sergipe negros, negros , negros) ver mismo hecho caminos historia así colonialistas neoliberal mediante métodoidea genealógica polifónica nómadas posidentitarias domesticada mangabeira

Abstract The article starts from the research as a moving practice; in the composition of territories of the act of researching as an experience. Inspired by the disruptive force of the twisting-twining of the Screws (revelry from Sergipe, derived from practices of resistance to the slavery of black people), we propose a thought-method of inventing ways of seeing, saying, and narrating from what is around us, a position in relation to the world and itself, engendering the idea that this world is not a given, but an effect of our practices. From this perspective, we try to question the very discursive and non-discursive practices of Psychology, in favor of opening trails, in which this knowledge can refund its own history, accentuating its discontinuities and heterogeneities and, thus, an attitude of facing the colonialist tendencies, now in their neoliberal versions. This way of searching is done by: operating a genealogical-cartographic idea-method and polyphonic writing; producing nomadic, minority, post-identity, decolonial war machines; and inventing with what is around us, in favor of knowledge and practices of local networks, which, like the mangabeira plant, do not allow domestication. practice experience twistingtwining twisting twining revelry Sergipe people, people , people) thoughtmethod thought method seeing saying us itself given perspective nondiscursive non Psychology trails history thus tendencies versions genealogicalcartographic genealogical cartographic ideamethod writing nomadic minority postidentity, postidentity post identity, identity post-identity machines networks plant domestication

Resumo O artigo parte da aposta na pesquisa como uma prática em movimento, na composição de territórios do ato de pesquisar como uma experiência. Inspiradas(os) na força disruptiva do torcer-retorcer dos Parafusos (folguedo sergipano, derivado de práticas de resistência à escravidão dos povos pretos), propomos um método-pensamento de inventar modos de ver, dizer e narrar a partir daquilo que está ao nosso redor, uma posição em relação ao mundo e a si mesmo, engendrando a ideia de que este mundo não é um dado, mas um efeito de nossas práticas. A partir dessa perspectiva, intentamos interpelar as próprias práticas discursivas e não discursivas da Psicologia, em favor de abrir trilhas nas quais esse saber possa refundar sua própria história, acentuando suas descontinuidades e heterogeneidades e, com isso, uma atitude de fazer frente às tendências colonialistas, agora em suas versões neoliberais. Esse modo de pesquisar se faz por: operar uma ideia-método genealógico-cartográfica e uma escrita polifônica; produzir máquinas de guerras nômades, minoritárias, pós-identitárias, decoloniais; e inventar com aquilo que está ao nosso redor em favor de saberes e fazeres das redes locais, que, tais como a planta mangabeira, não se deixam domesticar. movimento experiência Inspiradasos Inspiradas os Inspiradas(os torcerretorcer torcer retorcer folguedo sergipano pretos, pretos , pretos) métodopensamento método pensamento ver mesmo dado perspectiva Psicologia história isso colonialistas neoliberais por ideiamétodo genealógicocartográfica genealógico cartográfica polifônica nômades minoritárias pósidentitárias, pósidentitárias pós identitárias, identitárias pós-identitárias decoloniais locais mangabeira domesticar

Abstract The aim of this study was to evaluate the effect of the type of calving (normal or assisted) on the occurrence of puerperal uterine disorders and on the number of artificial inseminations (AI) per conception and pregnancy rate at 150 days postpartum (PPD). Cows were observed during parturition and the type of calving was classified as normal or assisted. Normal calving required no human interference, while assisted calving required a calf removal aid via vaginal access. There were 825 births, 7 stillbirths (0.85%) and 17 twins (2.06%). We analyzed 801 single births, from which 766 (95.63%) were normal and 35 (4.36%) assisted. Were evaluated the uterine disorders occurrence such as retained placenta combined with metritis (PR/ME) and clinical endometritis (CE). The overall occurrences were 10.24% (82/801) of RP/ME, 12.86% for CE and 5.12% for RP/ME and CE. Most of normal calving cows had healthy puerperium (73.89%), whereas a majority of assisted calving cows had uterine disorders (74.29%). The number of AI per conception was similar for cows that had either normal or assisted calving (2.39±0.08 and 3.00±0.43, P = 0.16). There was no evidence of negative influence of calving type on the 150 PPD pregnancy rate of lactating crossbreed dairy cows (P = 0.44). Healthy cows had higher 150 PPD pregnancy rate than cows affected by puerperium uterine disorders (51.65 vs. 42.92%). Normal calving crossbred dairy cows had a healthier puerperium, compared to cows with assisted calving which were more susceptible to puerperium uterine disorders. And cows with a health puerperium have a higher pregnancy rate at 150 days postpartum. (AI 15 PPD. . (PPD) interference access 82 births 0.85% 085 0 85 (0.85% 1 2.06%. 206 2.06% 2 06 (2.06%) 80 76 95.63% 9563 95 63 (95.63% 3 4.36% 436 4 36 (4.36% PR/ME PRME PR ME (PR/ME (CE) 1024 10 24 10.24 82/801 82801 (82/801 RPME RP 1286 12 86 12.86 512 5 5.12 73.89%, 7389 73.89% , 73 89 (73.89%) 74.29%. 7429 74.29% 74 29 (74.29%) 2.39±0.08 239008 39 08 (2.39±0.0 300043 00 43 3.00±0.43 0.16. 016 0.16 16 0.16) 0.44. 044 0.44 44 0.44) 51.65 5165 51 65 (51.6 vs 42.92%. 4292 42.92% 42 92 42.92%) (PPD 8 0.85 (0.85 20 2.06 (2.06% 95.63 956 9 6 (95.63 4.36 (4.36 (CE 102 10.2 82/80 8280 (82/80 128 12.8 5.1 738 73.89 (73.89% 742 74.29 (74.29% 2.39±0.0 23900 (2.39±0. 30004 3.00±0.4 01 0.1 04 0.4 51.6 516 (51. 429 42.92 0.8 (0.8 2.0 (2.06 95.6 (95.6 4.3 (4.3 10. 82/8 828 (82/8 12. 5. 73.8 (73.89 74.2 (74.29 2.39±0. 2390 (2.39±0 3000 3.00±0. 0. 51. (51 42.9 (0. 2. (2.0 95. (95. 4. (4. 82/ (82/ 73. (73.8 74. (74.2 2.39±0 239 (2.39± 300 3.00±0 (5 42. (0 (2. (95 (4 (82 (73. (74. 2.39± 23 (2.39 30 3.00± ( (2 (9 (8 (73 (74 2.39 (2.3 3.00 (7 2.3 3.0 3.

Resumo Objetivou-se avaliar em vacas leiteiras mestiças que pariram um bezerro vivo, o efeito do tipo de parto (normal ou assistido) na ocorrência de desordens uterinas puerperais e no número de inseminações artificiais (IA) por concepção e taxa de prenhez 150 dias pós-parto (DPP). As vacas foram monitoradas durante o parto e o tipo de parto foi classificado como normal ou assistido. O parto normal não precisou de interferência humana, enquanto o parto assistido precisou de auxílio para retirada do bezerro por via vaginal. Foram registrados 825 partos, sendo 7 natimortos (0,85%) e 17 gemelares (2,06%). Foram analisados 801 partos simples, dos quais 766 (95,63%) foram normais e 35 (4,36%) foram assistidos. Foram avaliadas a ocorrência de desordens uterinas como a retenção de placenta associada com metrite (RP/ME) e endometrite clínica (EC). A ocorrência das doenças foi de 10,24% (82/801) para RP/ME, 12,86% para EC e 5.12% para RP/ME com CE. A maioria das vacas com parto normal tiveram puerpério saudável (73,89%), enquanto a maioria das vacas com parto assistido apresentaram desordens uterinas (74,29%). O número de IA por concepção foi semelhante nas vacas que tiveram parto normal ou assistido (2,39±0,08 e 3,00±0,43, P = 0,16). Não houve evidência de influência negativa do tipo de parto na taxa de prenhez 150 DPP de vacas leiteiras mestiças em lactação (P = 0,44). Vacas saudáveis apresentaram maior taxa de prenhez 150 DPP do que vacas afetadas por desordens uterinas no puerpério (51,65 vs. 42,92%). Vacas leiteiras mestiças com parto normal tiveram um puerpério saudável, comparadas às que tiveram parto assistido, por sua vez foram mais susceptíveis as desordens uterinas no puerpério. E vacas com puerpério saudável resultaram em maiores taxas de prenhez aos 150 dias pós parto. Objetivouse Objetivou se vivo (IA 15 pósparto DPP. . (DPP) humana vaginal 82 0,85% 085 0 85 (0,85% 1 2,06%. 206 2,06% 2 06 (2,06%) 80 simples 76 95,63% 9563 95 63 (95,63% 3 4,36% 436 4 36 (4,36% assistidos RPME RP ME (RP/ME EC. (EC) 1024 10 24 10,24 82/801 82801 (82/801 1286 12 86 12,86 512 5 5.12 CE 73,89%, 7389 73,89% , 73 89 (73,89%) 74,29%. 7429 74,29% 74 29 (74,29%) 2,39±0,08 239008 39 08 (2,39±0,0 300043 00 43 3,00±0,43 0,16. 016 0,16 16 0,16) 0,44. 044 0,44 44 0,44) 51,65 5165 51 65 (51,6 vs 42,92%. 4292 42,92% 42 92 42,92%) (DPP 8 0,85 (0,85 20 2,06 (2,06% 95,63 956 9 6 (95,63 4,36 (4,36 (EC 102 10,2 82/80 8280 (82/80 128 12,8 5.1 738 73,89 (73,89% 742 74,29 (74,29% 2,39±0,0 23900 (2,39±0, 30004 3,00±0,4 01 0,1 04 0,4 51,6 516 (51, 429 42,92 0,8 (0,8 2,0 (2,06 95,6 (95,6 4,3 (4,3 10, 82/8 828 (82/8 12, 5. 73,8 (73,89 74,2 (74,29 2,39±0, 2390 (2,39±0 3000 3,00±0, 0, 51, (51 42,9 (0, 2, (2,0 95, (95, 4, (4, 82/ (82/ 73, (73,8 74, (74,2 2,39±0 239 (2,39± 300 3,00±0 (5 42, (0 (2, (95 (4 (82 (73, (74, 2,39± 23 (2,39 30 3,00± ( (2 (9 (8 (73 (74 2,39 (2,3 3,00 (7 2,3 3,0 3,