Abstract Objective Pain is the primary limitation to performing hysteroscopy. We aimed to evaluate the predictive factors of low tolerance to office hysteroscopic procedures. Methods Retrospective cohort study of the patients who underwent office hysteroscopy from January 2018 to December 2020 at a tertiary care center. Pain tolerance to office-based hysteroscopy was subjectively assessed by the operator as terrible, poor, moderate, good, or excellent. Categorical variables were compared with the use of the Chi-squared test; an independent-samples t-test was conducted to compare continuous variables. Logistic regression was performed to determine the main factors associated with low procedure tolerance. Results A total of 1,418 office hysteroscopies were performed. The mean age of the patients was 53 ± 13.8 years; 50.8% of women were menopausal, 17.8% were nulliparous, and 68.7% had a previous vaginal delivery. A total of 42.6% of women were submitted to an operative hysteroscopy. Tolerance was categorized as terrible or poor in 14.9% of hysteroscopies and moderate, good, or excellent in 85.1%. A terrible or poor tolerance was more frequently reported in menopausal women (18.1% vs. 11.7% in premenopausal women, p = 0.001) and women with no previous vaginal delivery (18.8% vs. 12.9% in women with at least one vaginal birth, p = 0.007). Low tolerance led more often to scheduling a second hysteroscopic procedure under anesthesia (56.4% vs. 17.5% in reasonable-to-excellent tolerance, p < 0.0005). Conclusion Office hysteroscopy was a well-tolerated procedure in our experience, but menopause and lack of previous vaginal delivery were associated with low tolerance. These patients are more likely to benefit from pain relief measures during office hysteroscopy. procedures 201 202 center officebased based moderate good Chisquared Chi squared test independentsamples independent samples ttest t 1418 1 418 1,41 5 138 13 8 13. years 508 50 50.8 178 17 17.8 nulliparous 687 68 7 68.7 426 42 6 42.6 149 14 9 14.9 851 85 85.1% 18.1% 181 18 (18.1 vs 117 11 11.7 0.001 0001 0 001 18.8% 188 (18.8 129 12 12.9 birth 0.007. 0007 0.007 . 007 0.007) 56.4% 564 56 4 (56.4 175 17.5 reasonabletoexcellent reasonable 0.0005. 00005 0.0005 0005 0.0005) welltolerated well tolerated experience 20 141 41 1,4 50. 17. 68. 42. 14. 85.1 18.1 (18. 11. 0.00 000 00 18.8 12. 56.4 (56. 0000 0.000 2 1, 85. 18. (18 0.0 56. (56 (1 0. (5 (

Abstract Cross-link density impacts most mechanical properties of rubber, therefore it is necessary to have a method to measure it. The most widely used method is via equilibrium swelling, however, it is time consuming and uses organic solvents. Dynamic Shear Test (DST) can be used to calculate both chemical and physical cross-links in rubber compounds in shorter times than by swelling equilibrium method, and without the use of solvents. In this work, equilibrium swelling using toluene and acetone was used to validate the dynamic shear tests for different nitrile rubber (NBR) compounds. The DST had a good correlation with the swelling equilibrium method using acetone, with a correlation coefficient of ~0,91, validating the use of DST. Moreover, the use of the Modified Guth-Gold equation (instead of Guth-Gold Equation with Medalia correction) also allowed to deduct the effect of carbon black on the cross-link density from the DST.