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Abstract This publication is an update of the “Consensus on the therapeutic management of atopic dermatitis - Brazilian Society of Dermatology” published in 2019, considering the novel, targeted-oriented systemic therapies for atopic dermatitis. The initial recommendations of the current consensus for systemic treatment of patients with atopic dermatitis were based on a recent review of scientific published data and a consensus was reached after voting. The Brazilian Society of Dermatology invited 31 experts from all regions of Brazil and 2 international experts on atopic dermatitis who fully contributed to the process. The methods included an e-Delphi study to avoid bias, a literature search and a final consensus meeting. The authors added novel approved drugs in Brazil and the indication for phototherapy and systemic therapy for AD. The therapeutical response to systemic treatment is hereby reported in a suitable form for clinical practice and is also part of this updated manuscript. Consensus 2019 targetedoriented targeted oriented voting 3 process eDelphi e Delphi bias meeting AD manuscript 201 20

https://doi.org/10.1016/j.abd.2023.04.003

Dermatophytosis: Clinical and therapeutic study in a reference center in the eastern Amazon
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Pires, Carla Andrea Avelar

; Silva, Luiz Filipe Matos da

; Fonseca, Thábata Chrystye Ribeiro Tenório

; Moreira, Amanda Gabay

; Brito, Mioni Thieli Figueiredo Magalhães de

; Colli, Guilherme Mestriner

; Santos, Maria Amélia Lopes dos

; Carneiro, Francisca Regina Oliveira

Portuguese Journal of Dermatology and Venereology

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jun 2022, Volume 80 N. 2 Pages 86 - 93

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: Dermatofitoses constituem as infecções fúngicas da pele, cabelo e unha mais comuns em seres humanos, acometendo cerca de 20% da população mundial e todas as faixas etárias. Objetivos: Analisar características clínicas, epidemiológicas e terapêuticas de pacientes com dermatofitoses atendidos num serviço de referência em dermatologia geral e tropical na região da Amazônia Brasileira. Métodos: Foram analisados 75 prontuários do período de janeiro de 2016 a janeiro de 2020, cujos dados sobre formas clínicas, tratamento e recorrência foram coletados em protocolo próprio dos pesquisadores. Foi utilizado o teste Qui-quadrado de aderência na análise estatística e para a tomada de decisão adotou-se p < 0,05. Resultados: Houve predomínio do sexo feminino, média de 49 anos de idade, e em 28% dos casos observaram-se mais de 10 lesões no mesmo indivíduo. O principal tipo de dermatofitose foi onicomicose em adultos, seguida por Tinea capitis (24%) na faixa etária pediátrica (média 11,39 anos). De forma geral, idosos (37,33%) e crianças (26,67%) foram os mais atingidos. Optou-se, na maioria dos casos, pelo tratamento com medicações tópicas e sistémicas combinadas, sendo a griseofulvina e a terbinafina as mais prescritas para o tratamento sistêmico e a ciclopirox olamina o principal tópico prescrito (36%). Apesar de 77,3% dos pacientes terem comparecido em consulta subsequente, 25,33% recidivaram em menos de um ano. Conclusão: Os dados analisados ressaltam a importância do diagnóstico e tratamento precoce das dermatofitoses, sobretudo em idades extremas —faixa etária pediátrica e idosos— além de destacar a importância ativa das medidas não farmacológicas na viabilização da redução de recidivas e morbilidade aos pacientes.

Abstract Introduction: Dermatophytosis is the most common fungal infection of the skin, hair, and nails in humans. It affects about 20% of the world's population in all age groups. Objectives: To analyze clinical, epidemiological, and therapeutic characteristics of patients diagnosed with dermatophytosis treated at a general and tropical dermatology reference service in the Brazilian Amazon region. Methods: We analyzed 75 medical records from January 2016 to January 2020, with a researchers' protocol to collect data on clinical forms, treatment, and recurrence. Statistical analysis used the chi-square test of adherence, and p < 0.05 was considered statistically significant. Results: There was a female predominance, mean age of 49 years and 28% of patients had more than 10 lesions. The dominant type of dermatophytosis was onychomycosis in adults, followed by Tinea capitis (24%) in the pediatric group (mean 11.39 years). The elderly (37.33%) and children (26.67%) were the most affected. In most cases, treatment with combined topical and systemic medications was chosen. Griseofulvin and terbinafine were the most prescribed for systemic treatment and ciclopirox olamine was the main prescribed topic (36%). Although 77.3% of the patients attended a follow-up appointment, 25.33% relapsed in less than one year. Conclusion: The analyzed data emphasizes the importance of early diagnosis and treatment of dermatophytosis, especially in the extreme age group —pediatric and elderly age groups— besides the active importance of non-pharmacological measures to reduce recurrences and morbidity for patients.

https://doi.org/10.24875/pjdv.m22000025

Confecção de Brincos de Borracha no Intraoperatório para Otimizar o Tratamento Cirúrgico de Quelóides no Lóbulo da Orelha: Série de Casos
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Brito, Juliana Bacellar Nunes de

; Silveira, Samira Oliveira

; Mota, Alline Oliveira das Neves

; Nascimento, Mayara Silva

; Carneiro, Francisca Regina Oliveira

Revista da Sociedade Portuguesa de Dermatologia e Venereologia

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jun 2021, Volume 79 N. 2 Pages 14 - 17

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: Quelóides são tumores benignos de pele causados por alterações no processo de cicatrização de feridas. As opções terapêuticas disponíveis são diversas e a associação entre as técnicas é comumente utilizada. Métodos: Efetuámos a avaliação do tratamento combinado de ressecção cirúrgica de quelóide no lóbulo da orelha com posterior colocação de brinco de pressão utilizando êmbolos estéreis de seringas de 5 mL, que permaneceram no local durante 30 dias, combinado com injecção intralesional de corticoide aos 15 dias. Resultados: Foram avaliados cinco pacientes (3M/2F) com média de 22 anos, com quelóides recidivantes dos lóbulos auriculares tratados no Hospital Jean Bitar, estado do Pará, no ano de 2019 a 2020. O procedimento decorreu sem incidentes e o resultado estético foi considerado muito bom, sem recidiva após 6 meses Conclusão: Este procedimento cirúrgico combinado e a confecção do brinco foi considerada de baixo custo, fácil reprodutibilidade e com bom resultado estético final e boa tolerabilidade

ABSTRACT Introduction: Keloids are benign skin tumors caused by changes in the wound healing process. There are various therapeutic options available and the combination of techniques is commonly used. Conclusion: Five patients underwent a combined treatment of surgical resection of a keloid in the earlobe with subsequent placement of a pressure earring and were evaluated using sterile plungers of 5 mL syringes. The procedures were performed at Jean Bitar Hospital in the state of Pará from 2019 to 2020. No local recurrence was observed. The earring production was considered low cost, easily reproducible, good aesthetic appearance, and good tolerability.

https://doi.org/10.29021/spdv.79.2.1343 12 downloads

Evaluation of Depression and Anxiety Disorders and Correlation with the Treatment of Patients with Psoriasis Vulgaris
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Machado, Adriana Kamilly Leitão Pitman

; Brito, Caio Vinicius Botelho

; Brito, João Augusto Gomes de Souza Monteiro de

; Pires, Carla Andrea Avelar

; Carneiro, Francisca Regina Oliveira

Revista da Sociedade Portuguesa de Dermatologia e Venereologia

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dec 2020, Volume 78 N. 4 Pages 12 - 18

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: A psoríase é uma doença crónica inflamatória multissistêmica com diversas comorbidades, entre elas estão os transtornos de ansiedade e de depressão. Metodologia: Avaliar a prevalência de ansiedade e depressão, respectivamente pelos questionários GAD-7 and PHQ-9 em relação com variáveis socio-demográficas e formas de tratamento. Resultados: Foram avaliados 90 pacientes (56 do género feminino), 41 pacientes (45,56%) utilizavam apenas tratamento tópico, 28 pacientes (31,11%) utilizavam metotrexato via oral e 21 (23,33%) utilizavam imunobiológicos (agentes anti-TNF-alfa). Observou-se que 47 pacientes dos avaliados (52,23%) apresentaram algum grau de depressão (leve, moderado ou severo) e que 53 pacientes (58,89%) apresentaram algum grau de transtorno de ansiedade (leve, moderado ou severo). Não houve relação estatística significante entre o quadro de ansiedade e de depressão e o score PASI, assim como a faixa etária, a empregabilidade ou a escolaridade. Houve associação estatística entre o quadro psiquiátrico e o género feminino (p<0,0001) e menor prevalência de depressão (p=0,0336) com o uso de imunobiológicos. Conclusão: Os achados ratificam os achados encontrados na literatura, nos quais o quadro psiquiátrico possui também uma ampla associação com a fisiopatogenia inflamatória da psoríase, em especial em relação ao TNF-alfa, de modo que terapias anti-TNF possam vir a ser uma alternativa para o tratamento de depressão ou de transtornos de ansiedade associados à psoríase.

ABSTRACT Introduction: Psoriasis is a chronic inflammatory multisystemic disease with several comorbidities, namely anxiety and depression disorders. Methods: In this study, the prevalence of these psychiatric entities was investigated by the PHQ-9 and GAD-7 questionnaries and related to the socio-demographic variables and to the forms of clinical treatment. Results: A total of 90 patients (56 females) were analyzed. Of these, 41 patients (45.56%) used topical treatment only, 28 patients (31.11%) used oral methotrexate and 21 patients (23.33%) used immunobiological agents (anti-TNF-alfa agents). It was observed that 47 patients (52.23%) presented some degree of depression (mild, moderate or severe) and 53 patients (58.89%) presented some degree of anxiety disorder (mild, moderate or severe). There was no statistical relationship between the anxiety and depression scores and the PASI score, as well as age, employability or schooling. There was a statistical association between psychiatric comorbidities and the female gender (p <0.0001). It was also observed a lower prevalence of depression (p = 0.0336) on patients using immunobiological treatments. Conclusion: The findings confirm published data, showing association of psychiatric conditions with psoriasis, especially in relation to TNF-alpha, so that anti-TNF therapies may become an alternative for the treatment of depression or anxiety disorders associated with psoriasis.

https://doi.org/10.29021/spdv.78.4.1224 13 downloads

Primary melanoma of leptomeninge in a patient with giant congenital melanocytic nevus,
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Machado, Adriana Kamilly Leitão Pitman

; Nunes, Débora Bacellar Cruz

; Carneiro, Francisca Regina Oliveira

; Mendes, Alena Margareth Darwich

Anais Brasileiros de Dermatologia

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jun 2020, Volume 95 N. 3 Pages 404 - 406

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.abd.2019.11.002 217 downloads

Consensus on the therapeutic management of atopic dermatitis - Brazilian Society of Dermatology
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Aoki, Valeria

; Lorenzini, Daniel

; Orfali, Raquel Leão

; Zaniboni, Mariana Colombini

; Oliveira, Zilda Najjar Prado de

; Rivitti-Machado, Maria Cecília

; Takaoka, Roberto

; Weber, Magda Blessmann

; Cestari, Tania

; Gontijo, Bernardo

; Ramos, Andrea Machado Coelho

; Silva, Claudia Marcia de Resende

; Cestari, Silmara da Costa Pereira

; Souto-Mayor, Silvia

; Carneiro, Francisca Regina

; Cerqueira, Ana Maria Mosca de

; Laczynski, Cristina

; Pires, Mario Cezar

Anais Brasileiros de Dermatologia

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apr 2019, Volume 94 N. 2 Pages 67 - 75

Abstract: En | Text: En | PDF: En

Abstract: BACKGROUND: Atopic dermatitis is a highly prevalent inflammatory and pruritic dermatosis with a multifactorial etiology, which includes skin barrier defects, immune dysfunction, and microbiome alterations. Atopic dermatitis is mediated by genetic, environmental, and psychological factors and requires therapeutic management that covers all the aspects of its complex pathogenesis. OBJECTIVES: The aim of this article is to present the experience, opinions, and recommendations of Brazilian dermatology experts regarding the therapeutic management of atopic dermatitis. METHODS: Eighteen experts from 10 university hospitals with experience in atopic dermatitis were appointed by the Brazilian Society of Dermatology to organize a consensus on the therapeutic management of atopic dermatitis. The 18 experts answered an online questionnaire with 14 questions related to the treatment of atopic dermatitis. Afterwards, they analyzed the recent international guidelines on atopic dermatitis of the American Academy of Dermatology, published in 2014, and of the European Academy of Dermatology and Venereology, published in 2018. Consensus was defined as approval by at least 70% of the panel. RESULTS/CONCLUSION: The experts stated that the therapeutic management of atopic dermatitis is based on skin hydration, topical anti-inflammatory agents, avoidance of triggering factors, and educational programs. Systemic therapy, based on immunosuppressive agents, is only indicated for severe refractory disease and after failure of topical therapy. Early detection and treatment of secondary bacterial and viral infections is mandatory, and hospitalization may be needed to control atopic dermatitis flares. Novel target-oriented drugs such as immunobiologicals are invaluable therapeutic agents for atopic dermatitis.

https://doi.org/10.1590/abd1806-4841.2019940210 4086 downloads

Ocular manifestations of psoriasis
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Cruz, Natasha Ferreira Santos da

; Brandão, Larissa Silva

; Cruz, Sérgio Ferreira Santos da

; Cruz, Sérgio Augusto Sequeira da

; Pires, Carla Andréa Avelar

; Carneiro, Francisca Regina Oliveira

Arquivos Brasileiros de Oftalmologia

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jun 2018, Volume 81 N. 3 Pages 219 - 225

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivos: Relatar as manifestações oculares observadas em pacientes com psoríase atendidos no Ambulatório de Dermatologia da X e encaminhados ao Y, no período de outubro de 2013 a agosto de 2014. Métodos: A amostra foi constituída por um grupo composto por 43 pacientes com psoríase e um grupo controle com 86 pacientes sem psoríase. Foi realizada uma entrevista clínica com dados epidemiológicos, aspectos clínicos da doença e terapia empregada, sendo todas as informações registradas em protocolo próprio. Posteriormente, realizou-se o exame dermatológico, no qual foi avaliado o índice de gravidade da Psoríase por área (PASI) e índice dermatológico de qualidade de vida (DLQI), e o exame oftalmológico completo, incluindo: Acuidade Visual, Biomicroscopia, Tonometria, Fundoscopia, Teste de Schirmer I, Tempo de Ruptura do Filme Lacrimal (TBUT), rosa bengala, índice de doença da superfície ocular (OSDI) e exames para glaucoma. Resultados: Observou-se que nos pacientes com psoríase houve frequência estatisticamente maior de envolvimento ocular, como olho seco (16,28%), provável olho seco (32,56%) e blefarite (16,28%). Além disso, os valores do rosa bengala e do OSDI apresentaram-se mais alterados nos pacientes com psoríase (p<0,05). Conclusão: Dessa forma, sugere-se que esses pacientes realizem exames oftalmológicos periódicos, já que as manifestações oculares podem progredir sem sintomatologia e ocorrer independentemente de fatores de risco.

ABSTRACT Purpose: We aimed to report the ocular manifestations observed in patients with psoriasis. Methods: Patients were included and referred to our ophthalmology clinic from dermatology clinics of Universidade do Estado do Pará between October 2013 and August 2014. Clinical interviews were conducted to identify relevant epidemiological data, clinical features, and treatment details, and data were recorded using the same protocol. Subsequent dermatological examinations were performed and disease severity was rated using the Psoriasis Area and Severity Index and the Dermatological Life Quality Index. Complete eye examination was conducted, including visual acuity, biomicroscopy, tonometry, fundoscopy, Schirmer I test, tear breakup time, rose bengal staining, ocular surface disease index, and glaucoma tests. Results: In total, we included 43 patients with psoriasis and 86 controls. Patients with psoriasis had statistically higher incidences of dry eye (16.28%), likely dry eye (32.56%), and blepharitis (16.28%). Furthermore, the rose bengal and ocular surface disease tests were more abnormal in patients with psoriasis (p<0.05). Conclusions: Patients with psoriasis should undergo regular eye exams, regardless of risk factors, to monitor for the progression of symptomatic or asymptomatic ocular manifestations.

https://doi.org/10.5935/0004-2749.20180044 4049 downloads

Development, applicability and effects of a pilot program of group cognitive-behavioral therapy in Brazilian adolescents with anorexia nervosa
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Pegado, Paula

; Alckmin-Carvalho, Felipe

; Leme, Danielle

; Carneiro, Francisca

; Kypriotis, Patrícia

; Camacho, Priscila

; Fleitlich-Bilyk, Bacy

Archives of Clinical Psychiatry (São Paulo)

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may 2018, Volume 45 N. 3 Pages 57 - 60

Abstract: En | Text: En | PDF: En

Abstract Background: Most of the clinical trials involving cognitive-behavioral therapy (CBT) for the treatment of anorexia nervosa (AN) used the individual therapy format, and few have been dedicated to adapting and assessing the effects of the group format. Objectives: To assess the applicability and effects of a group CBT program for Brazilian adolescents with AN. Methods: Open clinical trial with 22 patients with AN divided into an intervention group – IG (n = 11; CBT, psychiatry, nutrition and family psychoeducation-6 months) and a control group – CG (n = 11; psychiatry, nutrition and family psychoeducation-6 months). Data collected at baseline, at the end of groups and six months after the completion were: weight, height, body mass index and Eating Disorder Examination Questionnaire (EDE-Q) used to assess the severity of AN symptoms. Results: Baseline homogeneous groups, with 91% adherence in the IG vs. 54% in the CG (p = 0.05). Participants in both groups regained weight and decreased symptoms of eating disorders at the end of groups. Comparing the EDE-Q scores IG presented a statistically significant difference in the restraint subscale of the EDE-Q between the end-of-group and the follow-up (p = 0.01). Discussion: Group CBT program produced positive effects and was applicable in Brazilian adolescents with AN as an adjuvant to multidisciplinary treatment.

https://doi.org/10.1590/0101-60830000000158 1807 downloads

Urban American cutaneous leishmaniasis
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Carneiro, Francisca Regina Oliveira

; Amin, Gabriela Athayde

; Cruz, Lorena de Britto Pereira

; Daher, Belkis Azevedo

Anais Brasileiros de Dermatologia

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feb 2018, Volume 93 N. 1 Pages 156 - 158

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/abd1806-4841.20186713 1039 downloads

10.

DEVELOPMENT OF METRICS FOR ARTICLES PUBLISHED IN PROFESSIONAL MASTER'S COURSE
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Brito, Marcus Vinicius Henriques

; Carneiro, Francisca Regina Oliveira

Revista do Colégio Brasileiro de Cirurgiões

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2015, Volume 42 Suppl. 1 Pages 28 - 30

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Objetivo: Propor métrica para qualificar a produção veiculada através de artigos publicados em programas de mestrado profissional e, a partir daí, estabelecer orientação para a avaliação dos programas de pós-graduação da Medicina III. Método: Análise dos documentos de área de 2013 dos programas de pós-graduação senso estrito no que concerne à aplicação e mensuração de pontuação a artigos publicados, e criação de proposta para métrica do tema com vistas à avaliação quadrienal da Medicina III. Resultados: Foram avaliados os documentos de área das Medicinas I, II e III; Ciências Biológicas I e Interdisciplinar, assim como os relatórios de 2013 da CAPES. Todos os programas estabelecem métrica para "Classificação de Artigos Publicados" dentro de sua produção bibliográfica embora com percentuais diferentes respeitando suas especificidades. Com esses dados levantados e correlacionando-se sua pertinência com as áreas cirúrgicas, foi elaborada proposta de quantificação da qualidade dos artigos publicados para "Programas de Pós-graduação Profissionais" na área cirúrgica que possuem características próprias de acordo com suas diretrízes, direcionando assim sua produção científica preferencialmente para revistas técnicas. Conclusão: A métrica sugerida para artigos publicados, que deve ser incluída na produção intelectual do Documento de Área, deverá ser considerada para o extrato A1 = 100 pontos; A2 = 85 pontos; B1 = 80 pontos; B2 = 70 pontos; B3 = 60 pontos; B4 = 40 pontos e B5 = 20 pontos.

Objective: Propose metric to qualify the production conveyed through articles published in Professional Master's Programs and, from there, to establish guidance for the evaluation of postgraduate programs of Medicine III. Method: Analysis of the documents of 2013 area graduate programs strict sense concerning the application and measurement of score the articles published, and creation of proposal for metric of the theme with the quadrennial review of Medicine III. Results: Were evaluated the medicines area documents I, II and III; Biological Sciences (I) and Interdisciplinary, as well as the 2013 reports of CAPES. All programs establish metrics for "Classification of Published Articles" within its bibliographic production although with different percentages respecting its specificities. With these data collected and correlating their relevance with the surgical areas, was drafted proposal for quantification of the quality of the published articles to "Professional Postgraduate Programs" at surgical area that have specific characteristics according to their guidelines, directing their scientific production to technique journals preferably. Conclusion: The metric suggested for published articles, that should be included in intellectual production of the Area Document, should be considered for the extract A1 = 100 points; A2 = 85 points; B1 = 80 points; B2 = 70 points; B3 = 60 points; B4 = 40 points and B5 = 20 points.

https://doi.org/10.1590/0100-69912015S01011 1130 downloads

11.

Evaluation of cases of pemphigus vulgaris and pemphigus foliaceus from a reference service in Pará state, Brazil
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Pires, Carla Andréa Avelar

; Viana, Viviane Brito

; Araújo, Fernando Costa

; Müller, Silvia Ferreira Rodrigues

; Oliveira, Miguel Saraty de

; Carneiro, Francisca Regina Oliveira

Anais Brasileiros de Dermatologia

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jul 2014, Volume 89 N. 4 Pages 556 - 561

Abstract: En | Text: En | PDF: En

BACKGROUND: Pemphigusis a bullous, rare and chronic autoimmune disease. There are two major forms of pemphigus: vulgaris and foliaceus. Epidemiological data and clinical outcome in patients diagnosed in the Brazilian Amazon states are still rare. OBJECTIVES: To study the occurrence of the disease during the study period and analyze the epidemiological profile of patients, the most common subtype of pemphigus, and the clinical evolution of patients. METHODS: Retrospective analysis of medical records of hospitalized patients with pemphigus foliaceus and pemphigus vulgaris in the period from 2003 to 2010 in Dermatology Service of Hospital Fundação Santa Casa de Misericórdia do Pará, Belém, Northern Brazil. RESULTS: We found a total of 20 cases of pemphigus during the study period, 8 of which were of foliaceus pemphigus and 12 of vulgaris pemphigus. Pemphigus foliaceus had the predominance of male patients (75%), showed satisfactory clinical evolution, and was characterized by absence of pediatric cases. Pemphigus vulgaris affected more women (66.7%), showed mean hospital stay of 1 to 3 months (50%), and there were three cases of death (25%). The prescribed immunosuppressive drugs included prednisone with or without combination of azathioprine and/or dapsone. Sepsis was associated with 100% of the deaths. CONCLUSIONS: The occurrence of the disease is rare, there are no familiar/endemic outbreaks in the sample. Evolution is usually favorable, but secondary infection is associated with worse prognosis. The choice of best drugs to treat pemphigus remains controversial.

https://doi.org/10.1590/abd1806-4841.20142679 4222 downloads

12.

Tissue immunostaining for factor XIIIa in dermal dendrocytes of pityriasis alba skin lesions
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Carneiro, Francisca Regina Oliveira

; Amaral, Gabriela Borborema do

; Mendes, Maiana Darwich

; Quaresma, Juarez Antônio Simões

Anais Brasileiros de Dermatologia

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apr 2014, Volume 89 N. 2 Pages 245 - 248

Abstract: En | Text: En | PDF: En

BACKGROUND: Pityriasis alba affects 1% of the world population and about 9.9% of the children in Brazil. However, its etiology remains uncertain. OBJECTIVE: The objective of the present study was to evaluate the immunoexpression of factor XIIIa in dermal dendrocytes of skin lesions of pityriasis alba. METHOD: Twenty patients with pityriasis alba and 20 patients with atopic dermatitis underwent biopsy. The dermal dendrocytes marked by factor XIIIa were counted by means of immunohistochemical analysis. RESULTS: The mean amount of dermal dendrocytes found in the patients with pityriasis alba was 2, whereas in the patients with atopic dermatitis it was 4, with a statistically significant difference between them. A cutoff point of 3 cells/square inch was established to differentiate pityriasis alba from atopic dermatitis, with 80% sensibility and 90% specificity. CONCLUSION: We believe that pityriasis alba and atopic dermatitis should be considered different clinical forms within the spectrum of atopic disease, in which sun radiation plays an important role by modulating the progression of the disease.

https://doi.org/10.1590/abd1806-4841.20142201 2863 downloads

13.

Clinical, epidemiological, and therapeutic profile of dermatophytosis
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Pires, Carla Andréa Avelar

; Cruz, Natasha Ferreira Santos da

; Lobato, Amanda Monteiro

; Sousa, Priscila Oliveira de

; Carneiro, Francisca Regina Oliveira

; Mendes, Alena Margareth Darwich

Anais Brasileiros de Dermatologia

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apr 2014, Volume 89 N. 2 Pages 259 - 264

Abstract: En | Text: En | PDF: En

BACKGROUND: The cutaneous mycoses, mainly caused by dermatophyte fungi, are among the most common fungal infections worldwide. It is estimated that 10% to 15% of the population will be infected by a dermatophyte at some point in their lives, thus making this a group of diseases with great public health importance. OBJECTIVE: To analyze the clinical, epidemiological, and therapeutic profile of dermatophytosis in patients enrolled at the Dermatology service of Universidade do Estado do Pará, Brazil, from July 2010 to September 2012. METHOD: A total of 145 medical records of patients diagnosed with dermatophytosis were surveyed. Data were collected and subsequently recorded according to a protocol developed by the researchers. This protocol consisted of information regarding epidemiological and clinical aspects of the disease and the therapy employed. RESULTS: The main clinical form of dermatophyte infection was onychomycosis, followed by tinea corporis, tinea pedis, and tinea capitis. Furthermore, the female population and the age group of 51 to 60 years were the most affected. Regarding therapy, there was a preference for treatments that combine topical and systemic drugs, and the most widely used drugs were fluconazole (systemic) and ciclopirox olamine (topical). CONCLUSION: This study showed the importance of recurrent analysis of the epidemiological profile of dermatophytosis to enable correct therapeutic and preventive management of these conditions, which have significant clinical consequences, with chronic, difficult-totreat lesions that can decrease patient quality of life and cause disfigurement.

https://doi.org/10.1590/abd1806-4841.20142569 8646 downloads Cited 1 time in SciELO

14.

Psoriasiform Keratosis - Case report
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Pires, Carla Andréa Avelar

; Sousa, Brena Andrade de

; Nascimento, Carla do Socorro Silva do

; Moutinho, Ana Thais Machado

; Miranda, Mario Fernando Ribeiro de

; Carneiro, Francisca Regina Oliveira

Anais Brasileiros de Dermatologia

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apr 2014, Volume 89 N. 2 Pages 318 - 319

Abstract: En | Text: En | PDF: En

Psoriasiform Keratosis is a rare clinic entity. The etiopathogenesis remains unknown and the disease is characterized by a solitary, scaly or keratotic papule, or plaque mainly located on the extremities. Histopathological features closely resemble those of psoriasis. We report the case of a 70-year-old woman presenting a solitary and asymptomatic keratotic plaque, located on the back of the left leg, unresponsive to topical corticosteroids. We performed an excisional biopsy and histopathology was consistent with psoriasiform keratosis.

https://doi.org/10.1590/abd1806-4841.20142504 1977 downloads

15.

Pyoderma gangrenosum in a newborn - case report
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Carneiro, Francisca Regina Oliveira

; Santos, Maria Amélia Lopes dos

; Sousa, Brena Andrade de

; Nascimento, Carla do Socorro Silva do

; Amin, Gabriela Athayde

; Moutinho, Ana Thais Machado

Anais Brasileiros de Dermatologia

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dec 2013, Volume 88 N. 6 Pages 173 - 175

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O Pioderma gangrenoso é uma doença inflamatória rara, crônica e recorrente, de etiopatogenia desconhecida, caracterizada por uma ulceração não-infecciosa, necrotizante e dolorosa da pele. Geralmente, afeta adultos na faixa de 25 a 54 anos e raramente crianças (menos de 4%), nestes acomete preferencialmente cabeça e face, nádegas, região perianal e genital. Apresenta rápida resposta à corticoterapia sistêmica. Relata-se um caso de recém-nascida com lesões ulceradas de pioderma gangrenoso de fundo hemorrágico e necrótico distribuídas em abdômen, região genital e glútea com resposta rápida e efetiva à prednisona oral.

Pyoderma gangrenosum is a rare, inflammatory, chronic and recurrent disease of unknown etiology, characterized by noninfectious, necrotizing and painful cutaneous ulcers. Usually it affects adults aged between 25 and 54 years old and rarely children (less than 4%), in which it mainly affects the head, face, buttocks, genital and perianal region. The disease presents a quick response to systemic corticosteroids. We report a case of a newborn with hemorrhagic and necrotic ulcers, distributed in the abdomen, buttocks and genital region with rapid and effective response to oral prednisone.

https://doi.org/10.1590/abd1806-4841.20132601 7864 downloads

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