Abstract Objectives: To study the perception of young Portuguese adults about using mobile applications as a complement to oral health motivation. Methods: This cross-sectional descriptive study applied an online questionnaire to Portuguese individuals between 18 and 20 years old. The questionnaire was developed based on a literature review and assessed by a panel of experts before its application. It collected information about oral hygiene behaviors and the perception of using mobile apps for oral health motivation, including opinions on important functionalities. Variables’ absolute and relative frequencies were calculated. Results: The sample included 213 participants. About 73.2% of the participants considered oral health motivational mobile apps useful, but only 6.1% indicated having already used one. The most valued functionalities were information about oral diseases (86.9%), appointment reminders (85.4%), and a toothbrushing timer (84.5%). Conclusions: Most of the participants found oral health apps useful as a complement to oral health motivation. However, only a small minority reported having used these apps before. The functionalities evidenced in this study may be helpful for the development of mobile apps since they can be more directed to the population's expectations. Apps may be another way for healthcare professionals to motivate their patients to engage in oral health selfcare.

Resumo Objetivos: Estudar a perceção de jovens adultos portugueses sobre o uso das aplicações móveis como complemento da motivação para a saúde oral. Métodos: Estudo descritivo transversal, com aplicação de um questionário online a indivíduos portugueses, com idade entre os 18 e os 20 anos. O questionário foi desenvolvido com base numa revisão da literatura e avaliado por um painel de peritos antes da sua aplicação. Recolheu informação sobre os comportamentos de higiene oral e sobre a perceção da utilização de aplicações móveis para a motivação para a saúde oral, incluindo opiniões sobre funcionalidades mais ou menos importantes. Foram calculadas as frequências absolutas e relativas das variáveis. Resultados: A amostra incluiu 213 participantes. Cerca de 73,2% dos participantes consideraram as aplicações móveis de motivação para a saúde oral úteis, no entanto apenas 6,1% referiu já ter utilizado uma. As funcionalidades mais valorizadas foram: informação sobre doenças orais (86,9%), lembretes de consulta (85,4%) e temporizador de escovagem dos dentes (84,5%). Conclusões: A maioria dos participantes considerou a utilização de uma aplicação de saúde oral útil como complemento à motivação para a saúde oral, no entanto apenas uma pequena minoria referiu ter utilizado estas aplicações anteriormente. As funcionalidades evidenciadas neste estudo podem ser úteis para o desenvolvimento de aplicações móveis, de modo a serem mais direcionadas para as expectativas da população. A utilização de aplicações pode ser mais uma forma de os profissionais de saúde motivarem os seus pacientes para o autocuidado em saúde oral.

Resumo Objetivos: O presente trabalho pretendeu estudar a associação de aspetos relacionados com a qualidade de vida a características sociodemográficas, comportamentos de saúde oral e estado de saúde oral dos jovens de 18 anos da Região de Lisboa e Vale do Tejo, utilizando dados previamente recolhidos no III Estudo Nacional de Prevalência das Doenças Orais (ENPDO). Métodos: A amostra do III ENPDO foi constituída por 157 indivíduos com 18 anos, residentes na região de Lisboa e Vale do Tejo. O III ENPDO recolheu dados através de um questionário e de uma observação intraoral. O questionário recolheu informação sobre a qualidade de vida, dados sociodemográficos e comportamentos de saúde oral. A observação intraoral incluiu o registo de cárie dentária (ICDAS II) e hemorragia gengival (IPC modificado). A análise estatística utilizou os testes de Mann-Whitney e de Kruskal-Wallis (α=0,05). Resultados: De um modo geral, os indivíduos do sexo feminino, com um nível de escolaridade mais baixo, que nunca visitaram um profissional de saúde oral e com presença de cárie ou de hemorragia gengival apresentaram piores resultados (p<0,05). A presença de cárie foi o fator mais frequentemente associado a uma pior qualidade de vida, encontrando-se em 4 das 8 questões consideradas. Conclusões: Foram identificados alguns fatores relacionados com uma pior qualidade de vida. A consideração destes fatores é importante para um reforço das medidas preventivas, particularmente das relacionadas com a melhoria dos comportamentos de saúde oral e com o tratamento precoce das doenças orais.

Abstract Objectives: The present study investigated the association between quality of life and sociodemographic characteristics, oral health behaviors, and oral health status in 18-year-old individuals in the Region of Lisbon and Tagus Valley, using data from the III National Study of the Prevalence of Oral Diseases (NSPOD). Methods: The sample of the III NSPOD consisted of 157 18-year-old individuals living in Lisbon and Tagus Valley region. The III NSPOD collected data by a questionnaire and an intraoral observation. The questionnaire included questions about quality of life, sociodemographic data, and oral-health behaviors. The intraoral observation included recording of dental caries (ICDAS II) and gingival bleeding (modified CPI). Statistical analysis used the Mann-Whitney and Kruskal-Wallis tests (α=0.05). Results: In general, female individuals with a lower level of education who had never visited an oral health professional and had caries or gingival hemorrhage had worse results (p<0.05). The presence of dental caries was the factor most frequently associated with worse quality of life, as found in 4 of the 8 questions considered. Conclusions: Some factors related to a worse quality of life were identified. These factos should be considered to reinforce preventive measures, particularly those related to improving oral health behaviors and the early treatment of oral diseases.

Abstract Musical hallucinosis is a disease with a poorly understood pathophysiology, in which hearing loss and mood disorders can be triggering factors. Although there is no consensual approach, psychoeducation plays a central role. We present the clinical case of an 84-year-old woman with hearing loss and depressive disorder reactive to her husband's role as a caregiver. Four days after the introduction of antidepressant medication she developed auditory musical hallucinosis, where she listened to songs from her childhood continuously throughout the day. These complaints remained despite the interruption of the antidepressant and the prescription of antipsychotics. After screening for organic pathologies, psychoeducation was initiated, focusing on increasing social activity and auditory stimuli and optimizing co-morbid pathologies. The patient had a favorable evolution and almost complete resolution of the complaints.

Resumo A alucinose musical é uma doença com fisiopatologia mal-esclarecida, na qual a hipoacusia e as patologias do humor poderão ser fatores desencadeantes. Apesar de não existir uma abordagem terapêutica consensual, a psicoeducação desempenha um papel fulcral. Apresenta-se o caso de uma mulher de 84 anos de idade com hipoacusia e perturbação depressiva reativa ao papel de cuidadora do marido. Quatro dias após introdução de medicação antidepressiva iniciou quadro de alucinose musical auditiva, onde ouvia músicas da sua infância de forma contínua, ao longo do dia. Estas queixas mantiveram-se apesar da interrupção da terapêutica antidepressiva e mostraram-se refratárias à toma de antipsicóticos. Após despiste de patologias orgânicas foi iniciada psicoeducação, com enfoque no aumento da atividade social e estímulos auditivos e otimização das patologias co-mórbidas, tendo a doente apresentado evolução favorável e resolução quase completa das queixas.

Abstract Objective The purpose of this study was to analyze the available evidence regarding the efficacy of iPDE5 in the treatment of female sexual dysfunction (FSD). Methods A comprehensive literature search was conducted in March 2023 through the main scientific databases. Results A total of 53 articles were identified, out of which, 6 met the predefined inclusion criteria. All of these were randomized controlled trials. Among the included studies, 4 demonstrated the effectiveness of sildenafil in improving sexual response and addressing FSD, while 2 studies failed to establish its efficacy in this context. Conclusion Overall, the efficacy of sildenafil in the treatment of FSD remains controversial and inconclusive based on the available evidence. Further research is necessary to clarify the therapeutic potential of iPDE5 in addressing FSD and to better understand the factors that influence treatment outcomes. iPDE FSD. . (FSD) 202 databases 5 identified which criteria trials context Overall outcomes (FSD 20

Abstract Introduction: A promising technique to treat persistent olfactory impairment has recently been explored: platelet rich plasma (PRP) injection into the olfactory mucosa. Objectives: This study aimed to determine efficacy, safety, and feasibility of a new PRP injection protocol in treating persistent COVID-19 induced olfactory dysfunction (pCIOD). Material and Methods: Patients with pCIOD lasting for ≥ 12 months were enrolled. All patients had previously performed olfactory training and adjuvant therapy without achieving substantial improvement. Olfactory perception threshold (OPT) and visual analog scale (VAS) were measured at baseline, one month and three months after injection. Results: Twenty patients were enrolled. There was a significant change in OPT after injection (mean baseline OPT: 4.36 ± 1.6 versus 1-month after injection: 6.9 ± 2.6, p = 0.012 versus 3-months after injection: 7.2 ± 2.8, p =0.009). No severe complications were reported. Conclusions: Single-site PRP injection into the olfactory mucosa is a novel, safe and effective approach that may enhance olfactory recovery in pCIOD patients.

Resumo Introdução: A injeção de plasma rico em plaquetas (PRP) na mucosa olfativa é uma técnica inovadora e promissora no tratamento da disfunção olfativa persistente. Objetivos: O objetivo deste estudo foi determinar a eficácia, segurança e viabilidade de um novo protocolo de injeção de PRP no tratamento da disfunção olfativa persistente induzida pela COVID-19 (DOPIC). Material e métodos: Foram incluídos doentes com DOPIC com duração igual ou superior a 12 meses. Todos tinham previamente realizado treino olfativo e terapêutica adjuvante sem terem obtido melhoria significativa. Os valores do limiar de perceção olfativa (LPO) e da escala visual analógica (EVA) foram medidos antes, 1 mês e 3 meses após a injeção. Resultados: Foram incluídos 20 doentes. Constatou-se uma alteração significativa nos valores de LPO após a injeção (valores médios de LPO de base: 4,36 ± 1,6 versus 1 mês pós-injeção: 6,9 ± 2,6, p = 0,012 versus 3 meses pós-injeção: 7.2 ± 2.8, p = 0.009). Não foram registadas complicações graves. Conclusões: A injeção de PRP em local único na mucosa olfativa é uma nova abordagem, segura e eficaz, que pode melhorar a recuperação olfativa nos doentes com DOPIC.

Abstract Pitaya is a rich source of bioactive compounds, such as polyphenols and betalains. Moreover, these compounds has been associated with reduced risk of type 2 diabetes mellitus. The aim of this study is to evaluate the effect of this fruit on glycemia and oxidative stress in aloxan-induced diabetic mice. Thus, considering that In the in vivo assays, the mice were divided into 5 groups (n = 6): (a) healthy group treated with water; (b) diabetic mice treated with metformin at 200 mg/kg body weight diluted in water; (c) untreated diabetic mice; (d) diabetic mice treated with pitaya at 200 mg/kg and (e) diabetic mice treated with pitaya at 400 mg/kg of body weight diluted in water. The results shows that pitaya was able significantly to reduce blood glucose (p < 0.05) (200 mg/kg); significantly reduce cholesterol (200 and 400 mg/kg) and significantly increase HDL-c (400 mg/kg) levels. In the oxidative stress experiment, Malondialdehyde levels in the liver were significantly reduced (p < 0.05) in the groups treated with pitaya, when compared to the other groups, suggesting lower lipid peroxidation. The consumption of pitaya reduced the blood glucose and cholesterol and increase the HDL, in addition, the lipid peroxidation - which is common in diabetic patients, was reduced. betalains Moreover mellitus aloxaninduced aloxan induced Thus assays n 6 6) (a water b (b 20 mgkg mg kg c (c d (d e (e 40 p 0.05 005 0 05 (20 HDLc HDL (40 experiment addition patients 4 0.0 00 (2 (4 0. (

ABSTRACT Objective: To evaluate the influence of maternal pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) on blood glucose levels at diagnosis of gestational diabetes mellitus (GDM) and obstetric/neonatal outcomes. Subjects and methods: Retrospective cohort study including 462 women with GDM and singleton pregnancy delivered in our institution between January 2015 and June 2018 and grouped according to BMI/GWG. Results: The diagnosis of GDM was more likely to be established in the 1st trimester (T) in women with obesity than in normal-weight (55.8% vs 53.7%, p = 0.008). BMI positively and significantly correlated with fasting plasma glucose (FPG) levels in the 1stT (rs = 0.213, p = 0.001) and 2ndT (rs = 0.210, p = 0.001). Excessive GWG occurred in 44.9% women with overweight and in 40.2% with obesity (p < 0.001). From women with obesity, 65.1% required pharmacological treatment (p < 0.001). Gestational hypertension (GH) was more frequent in women with obesity (p = 0.016). During follow-up, 132 cesareans were performed, the majority in mothers with obesity (p = 0.008). Of the 17 large-for-gestational-age (LGA) birthweight delivered, respectively 6 and 9 were offsprings of women with overweight and obesity (p = 0.019). Maternal BMI had a predictive value only for macrosomia [aOR 1.177 (1.006-1.376), p = 0.041]. BMI and GWG positively correlated with birthweight (rs = 0.132, p = 0.005; rs = 0.188, p = 0.005). Conclusion: Maternal obesity is related with a major probability of diagnosis of GDM in 1stT, fasting hyperglycemia in 2ndT and a more frequent need for pharmacological therapy. Pre-gestational obesity is associated with GH, cesarean delivery and fetal macrosomia.

Abstract Malaria is a disease caused by Plasmodium spp. protozoa. The ability of Plasmodium to develop resistance to current antimalarial drugs makes the study of chemotherapeutic alternatives extremely important. This study aimed to evaluate the antimalarial activity of compound 3286938 (1-(3-benzyloxy-4-methoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propan-1-one), which presents in its structure a 3,4,5-trimethoxyphenyl group, in vitro, using the W2 strain of P. falciparum and against circulating strains of P. vivax and P. falciparum from the state of Rondônia. The compound 3286938 obtained an IC50 of 24.4 µM against the W2 strain of P. falciparum, and against the circulating strains, it presented a median (MD)=38.7 µM for P. vivax and MD=6.7 µM for P. falciparum. As for toxicity, 3286938 showed CC50 > 500 µM for VERO and HepG2 strains with a selectivity index greater than 12.9, a ratio calculated for P. falciparum and P. vivax regarding Vero and HepG2 cells. The compound was not considered hemolytic in in vitro assays, thus indicating the specificity of its antiplasmodial action. Based on the results presented, and considering the unprecedented character of the compound, it can be concluded that 3286938 was shown to be promising for complementary in vitro and in vivo studies aiming to produce effective antiplasmodial action. spp protozoa important 328693 13benzyloxy4methoxyphenyl33,4,5trimethoxyphenylpropan1one, 13benzyloxy4methoxyphenyl3345trimethoxyphenylpropan1one benzyloxymethoxyphenyltrimethoxyphenylpropanone 1 3 benzyloxy 4 methoxy phenyl 3,4,5 trimethoxy propan one , 5 (1-(3-benzyloxy-4-methoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propan-1-one) 3,4,5trimethoxyphenyl 345trimethoxyphenyl trimethoxyphenyl group W P Rondônia IC IC5 244 24 24. MD=38.7 MD387 MD =38.7 38 7 (MD)=38. MD67 6 MD=6. toxicity CC CC5 50 HepG 129 12 9 12.9 cells assays action 32869 13benzyloxy4methoxyphenyl33 5trimethoxyphenylpropan1one methoxyphenyl trimethoxyphenylpropan 13benzyloxy4methoxyphenyl33,4,5trimethoxyphenylpropan1one 345 3,4, (1-(3-benzyloxy-4-methoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propan-1-one 5trimethoxyphenyl 2 MD=38. MD38 387 =38. (MD)=38 MD6 MD=6 12. 3286 benzyloxymethoxyphenyl 13benzyloxy4methoxyphenyl3 trimethoxyphenylpropanone 34 3,4 MD=38 MD3 =38 (MD)=3 MD= 328 13benzyloxy4methoxyphenyl 3, MD=3 =3 (MD)= 32 = (MD) (MD

ABSTRACT Objective: To evaluate the influence of maternal pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) on blood glucose levels at diagnosis of gestational diabetes mellitus (GDM) and obstetric/neonatal outcomes. Subjects and methods: Retrospective cohort study including 462 women with GDM and singleton pregnancy delivered in our institution between January 2015 and June 2018 and grouped according to BMI/GWG. Results: The diagnosis of GDM was more likely to be established in the 1st trimester (T) in women with obesity than in normal-weight (55.8% vs 53.7%, p = 0.008). BMI positively and significantly correlated with fasting plasma glucose (FPG) levels in the 1stT (rs = 0.213, p = 0.001) and 2ndT (rs = 0.210, p = 0.001). Excessive GWG occurred in 44.9% women with overweight and in 40.2% with obesity (p < 0.001). From women with obesity, 65.1% required pharmacological treatment (p < 0.001). Gestational hypertension (GH) was more frequent in women with obesity (p = 0.016). During follow-up, 132 cesareans were performed, the majority in mothers with obesity (p = 0.008). Of the 17 large-for-gestational-age (LGA) birthweight delivered, respectively 6 and 9 were offsprings of women with overweight and obesity (p = 0.019). Maternal BMI had a predictive value only for macrosomia [aOR 1.177 (1.006-1.376), p = 0.041]. BMI and GWG positively correlated with birthweight (rs = 0.132, p = 0.005; rs = 0.188, p = 0.005). Conclusion: Maternal obesity is related with a major probability of diagnosis of GDM in 1stT, fasting hyperglycemia in 2ndT and a more frequent need for pharmacological therapy. Pre-gestational obesity is associated with GH, cesarean delivery and fetal macrosomia.

Resumo Introdução: O pé pendente define-se pela incapacidade em elevar o pé por diminuição da força dos músculos dorsiflexores. Para elaborar um plano de tratamento é necessário determinar a sua etiologia. Cabe, assim, ao médico de família reconhecer as situações em que a gestão desta entidade poderá ser feita exclusivamente em cuidados de saúde primários, diferenciando-as das que poderão exigir avaliação e orientação em meio hospitalar. Descrição do Caso: Homem de 71 anos com hipertensão arterial e dislipidemia, medicado com indapamida. Em consulta com o médico de família referia que, há dois dias, havia permanecido sentado por duas horas com a perna direita cruzada sobre o membro inferior contralateral. Ao levantar-se notou dormência do pé direito, o qual não conseguia elevar. À observação apresentava marcha em steppage, com pé direito pendente e diminuição da sensibilidade do dorso do mesmo. Foi pedida eletromiografia, que documentou acentuada lesão axonal do nervo peroneal comum direito abaixo do colo do perónio, compatível com compressão prolongada. Foi submetido a sessões de fisioterapia, demonstrando resolução completa do quadro após três meses. Comentário: A neuropatia do nervo peroneal comum é a causa principal de pé pendente e a terceira neuropatia focal mais frequente, depois do nervo mediano e nervo cubital. A etiologia mais frequente é a compressiva. O local mais afetado é onde o nervo contorna o colo do perónio, manifestando-se por marcha em steppage, consequente à diminuição da força dos músculos dorsiflexores do pé. Embora o diagnóstico seja habitualmente clínico, a maioria dos pacientes requer eletromiografia. O tratamento inicial costuma ser conservador, sendo comum ocorrer resolução das queixas em três meses. Esta é uma condição que poderá ser pouco frequente na prática clínica em medicina geral e familiar, mas cuja abordagem poderá, muitas vezes, ser feita em cuidados de saúde primários. É importante saber tranquilizar os pacientes quanto à semiologia, abordagem terapêutica e prognóstico.

Abstract Introduction: Foot drop is defined by the inability to elevate the foot due to diminished strength of the dorsiflexor muscles. To elaborate a treatment plan, it is necessary to determine its etiology. Thus, the family doctor must recognize the situations in which the management of foot drop can be done exclusively in primary health care, differentiating from those that may require observation and assessment in-hospital care. Case description: 71-year-old man with arterial hypertension and dyslipidemia, medicated with indapamide. An appointment with the family doctor referred that, two days ago, had remained seated for two hours with the right leg crossed over the contralateral lower limb. By getting up, the patient noticed right foot numbness and inability to elevate the same foot. At the physical examination, he presented a steppage gait, with right foot drop and decreased sensitivity of the back of the foot. It was requested electromyography, which documented severe axonal damage of the right common peroneal nerve below the fibular neck, compatible with prolonged compression. The patient was submitted to physiotherapy sessions, demonstrating complete clinical resolution of foot drop after three months. Comment: The neuropathy of the common peroneal nerve is the main cause of foot drop and the third most frequent focal neuropathy, after the median nerve and cubital nerve. Compression remains the most frequent etiology. The most affected site is at the level of the fibular neck, manifested by steppage gait, consequent to decreased strength of the dorsiflexor muscles of the foot. Even though the diagnosis is usually clinical, most of the patients require electromyography. The initial treatment tends to be conservative, with a frequent resolution of the complaints in three months. This is a condition that may be uncommon in family medicine’s clinical practice, but its approach could be, many times, managed in primary health care. It is important to know how to reassure the patients about the semiology, therapeutic approach, and prognosis.

ABSTRACT OBJECTIVE: To investigate how sociodemographic conditions, political factors, organizational confidence, and non-pharmaceutical interventions compliance affect the COVID-19 vaccine hesitancy in Brazil. METHODS: Data collection took place between November 25th, 2020 and January 11th, 2021 using a nationwide online survey. Subsequently, the researches performed a descriptive analysis on the main variables and used logistic regression models to investigate the factors associated with COVID-19 vaccine hesitancy. RESULTS: Less concern over vaccine side effects could improve the willingness to be vaccinated (probability changed by 7.7 pp; p < 0.10). The current vaccine distrust espoused by the Brazilian president is associated with vaccine hesitancy, among his voter base. Lower performance perception (“Very Bad” with 10.7 pp; p < 0.01) or higher political opposition (left-oriented) regarding the current presidency is associated with the willingness to be vaccinated. Higher compliance with non-pharmaceutical interventions (NPIs) is usually positively associated with the willingness to take the COVID-19 vaccine (+1 score to NPI compliance index is associated with higher willingness to be vaccinated by 1.4 pp, p < 0.05). CONCLUSION: Willingness to be vaccinated is strongly associated with political leaning, perceived federal government performance, vaccine side effects, and compliance with non-pharmaceutical interventions (NPIs).

ABSTRACT OBJECTIVE: To investigate how sociodemographic conditions, political factors, organizational confidence, and non-pharmaceutical interventions compliance affect the COVID-19 vaccine hesitancy in Brazil. METHODS: Data collection took place between November 25th, 2020 and January 11th, 2021 using a nationwide online survey. Subsequently, the researches performed a descriptive analysis on the main variables and used logistic regression models to investigate the factors associated with COVID-19 vaccine hesitancy. RESULTS: Less concern over vaccine side effects could improve the willingness to be vaccinated (probability changed by 7.7 pp; p < 0.10). The current vaccine distrust espoused by the Brazilian president is associated with vaccine hesitancy, among his voter base. Lower performance perception (“Very Bad” with 10.7 pp; p < 0.01) or higher political opposition (left-oriented) regarding the current presidency is associated with the willingness to be vaccinated. Higher compliance with non-pharmaceutical interventions (NPIs) is usually positively associated with the willingness to take the COVID-19 vaccine (+1 score to NPI compliance index is associated with higher willingness to be vaccinated by 1.4 pp, p < 0.05). CONCLUSION: Willingness to be vaccinated is strongly associated with political leaning, perceived federal government performance, vaccine side effects, and compliance with non-pharmaceutical interventions (NPIs).

RESUMO Tendo em vista os diferentes contextos e transições nas vidas dos jovens, este artigo analisa as vulnerabilidades daqueles que se encontram sem trabalhar e sem estudar, a partir de dados empíricos produzidos com jovens de Recife. Com base nisso, o artigo discute como o reconhecimento das diferentes vulnerabilidades pode contribuir para a formulação de políticas públicas mais adequadas para os jovens que se encontram nessa situação.

ABSTRACT In light of the different contexts and transitions in the lives of young people, this article analyzes the vulnerabilities of the group of young people not in education, employment or training (NEETs) based on empirical data produced with young people in Recife. The article discusses how the recognition of different vulnerabilities of this target group can contribute to the formulation of public policies that are more appropriate for their needs.

Resumo A angina de Ludwig apresenta-se como uma celulite grave que envolve o espaço submandibular, de início agudo e evolução rapidamente progressiva. Descreve-se o quadro clínico de um homem de 33 anos com uma tumefação submandibular de agravamento progressivoassociada a obstrução da via aérea e necessidade de ventilação mecânica invasiva. Imagiologicamente, apresentava extenso processo fleimonoso dos tecidos moles do pescoço, com ponto de partida em cáries dentárias homolaterais. Foi instituída a drenagem do abcesso e antibioterapia, sem evidência de melhoria. Careceu de intervenção cirúrgica, com evolução paulatina, mas favorável. Este caso demonstra que o diagnóstico e tratamento precoces são fundamentais para o sucesso terapêutico.

Abstract Ludwig’s angina is a severe cellulitis involving the submandibular space, with acute onset and rapidly progressive evolution. We describe the case of a 33-year-old man with a progressive submandibular swelling associated with an airway obstruction that required mechanical ventilation. Radiologically, the patient presented with an extensive phlegmonous process of the soft tissues of the neck, originating from homolateral dental caries. Abscess drainage and antibiotic therapy were performed, without evidence of improvement. Surgical intervention was required, resulting in slow but favorable evolution. This case shows that successful treatment depends on early diagnosis and treatment.