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au:"Buzzoleti, Fernando da Costa"

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Diarréia como manifestação inicial de lúpus eritematoso sistêmico
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Cardoso, Marcos de Figueiredo

; Franco, Denilson S.

; Melo, Ana Caroline Sobral

; Paulino, Eduardo

; Narciso-Schiavon, Janaína Luz

; Schiavon, Leonardo de Lucca

; Latorre, Luiz Carlos

; Buzzoleti, Fernando da Costa

Revista Brasileira de Reumatologia

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jun 2008, Volume 48 N. 3 Pages 184 - 187

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O lúpus eritematoso sistêmico (LES) é uma doença crônica que acomete principalmente mulheres entre a terceira e quinta década de vida, multissistêmica, freqüentemente afetando os rins e o sistema nervoso central. Os sintomas relacionados ao trato gastrintestinal, apesar de comuns, quando ocorrem abrindo o quadro clínico, raramente levam ao diagnóstico por causa de sua baixa especificidade. Foi relatado um caso de LES cuja manifestação inicial foi diarréia crônica.

Systemic Lupus Erythematosus (SLE) is a chronic multissystemic disease that compromises women between the third and the fifth decade and frequently evolves the kidneys and the central nervous system. Gastrointestinal symptoms are usual however, when they appear as first symptoms, they rarely lead to lupus diagnosis for its low specificity. We report a case of SLE in which the initial manifestation was diarrhea.

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Lesão lítica de mandíbula em mulher com mieloma múltiplo usuária de bisfosfonato
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Lima, Carla Andrade

; Torres, Lucas Rios

; Gualdani, Lourdes Marangoni

; Narciso-Schiavon, Janaína Luz

; Schiavon, Leonardo de Lucca

; Latorre, Luiz Carlos

; Buzzoleti, Fernando da Costa

Revista Brasileira de Reumatologia

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feb 2008, Volume 48 N. 1 Pages 59 - 61

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Os bisfosfonatos são comumente utilizados no tratamento do mieloma múltiplo e em outras neoplasias com metástases ósseas. Geralmente são bem tolerados, entretanto osteonecrose de mandíbula é um efeito adverso recentemente relatado com uso de bisfosfonatos endovenosos. Relata-se um caso de osteonecrose de mandíbula em paciente submetido ao tratamento de mieloma múltiplo com quimioterapia e pamidronato endovenoso.

Bisphosphonates are commonly used in the treatment of multiple myeloma and other bone metastatic neoplasias. They are usually well tolerated; however osteonecrosis of the jaw is a recently reported side effect seen with the use of parenteral bisphosphonates. We report a case of osteonecrosis of the jaw in a patient treated for multiple myeloma with chemotherapy and parenteral pamidronate.

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Bilateral adrenal histoplasmosis in an immunocompetent man
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Benevides, Carlos Frederico Lopes

; Durães, Ronilson Oliveira

; Aquino, Bianca

; Schiavon, Leonardo de Lucca

; Narciso-Schiavon, Janaína Luz

; Buzzoleti, Fernando da Costa

Revista da Sociedade Brasileira de Medicina Tropical

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apr 2007, Volume 40 N. 2 Pages 230 - 233

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Histoplasmose é uma doença fúngica endêmica no Brasil que pode se apresentar como infecção pulmonar crônica ou na forma disseminada. A histoplasmose disseminada freqüentemente acomete a glândula adrenal; entretanto, ocorre mais em pacientes imunossuprimidos e de forma unilateral. Relatamos um caso de um homem idoso imunocompetente com história de perda de peso, febre e massa adrenal bilateral que foi tratada com itraconazol, com sucesso.

Histoplasmosis is a fungal disease that is endemic in Brazil. It may present as chronic pulmonary infection or in disseminated form. Disseminated histoplasmosis frequently affects the adrenal gland; however, unilateral involvement in immunosuppressed patients is the usual presentation. We report a case of an elderly immunocompetent male with history of weight loss, fever and bilateral adrenal mass who was successfully treated with itraconazole.

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