Se evaluó la presencia de infecciones maláricas en individuos asintomáticos en la población Jivi de Puente Parhueña. El estudio fue de tipo prospectivo en tres momentos. El diagnóstico parasitológico se realizó mediante el examen convencional de gota gruesa y extendido (GGE) y la reacción en cadena de la polimerasa (PCR). El diagnóstico por microscopia indicó 2% (5/261) de láminas positivas en Abril, 1% (3/274) en Septiembre y 4% (5/135) en Diciembre. La PCR para Plasmodium spp., fue 46% (26/57) en abril, 49% (28/57) en Septiembre y 35% (20/57) en Diciembre. En los tres momentos predominó la presencia de P. vivax. La prueba de ELISA demostró 72% (41/57) seroreactivos en Abril, 53% (30/57) en Septiembre y 60% (34/57) en Diciembre. En Puente Parhueña habitan individuos con infecciones maláricas asintomáticos, con persistencia de anticuerpos antimalaricos, que probablemente representan un reservorio de gametocitos dentro de la comunidad.

The study was carried out to determine the present malaria infection in the asymptomatic Jivi people of Puente Parhueña. The study was prospective over three periods of time. The parasitological diagnoses were from thick and thin blood smears (GGE) and polymerase chain reaction (PCR). The antibody search was performed by ELISA. Microscopy of the slides detected the following positive results: 2% (2/261) April, 1% (3/274) September and 4% (5/135) December. Detection of Plasmodium by PCR was 46% (26/57) in April, 49% (28/57) in September y 35% (20/57) in December. Plasmodium vivax infected individuals predominated during these 3 times. Positives for ELISA were 72% (41/57) in April, 53% (30/57) September and 60% (34/57) December. The study demonstrated that people living in Puente Parhueña presented asymptomatic malaria infection with malaria antibodies persistence which likely represents a gametocyte potential reservoir for infection among the population.

Entre 1993 y 2005, se han realizado numerosos estudios de suelos en un amplio sector del barrio Laureles (Medellín, Departamento de Antioquia, Colombia), que han tenido como objeto la identificación de la estratigrafía de la zona y la determinación de la capacidad portante del suelo. Los ensayos de campo y laboratorio realizados durante estas exploraciones son resistencia a la penetración estándar (Standar Penetration Test) SPT y ensayos de laboratorio de resistencia a la compresión simple. A estos datos se les realizó un proceso de georeferenciación para profundidades especificas de 2.5, 5.0 y 7.5 metros para el ensayo SPT; y 2.30 y 3.30 metros para los ensayos de compresión simple. Mediante el uso de técnicas geoestadísticas (interpolación espacial), se modelaron superficies para el área en estudio, con el propósito de encontrar información en locaciones en las cuales no se han realizado estudios de suelos.

Between 1993 and 2005, there have been numerous studies of soils in a wide sector of the Laureles neighborhood ( Medellin, Antioquia, Colombia ), which have aimed to identify the stratigraphy of the area and determine the bearing capacity of soil. Field tests and laboratory examinations realized during these explorations are resistance to the standard penetration (Standard Penetration Test) SPT and resistance laboratory tests to simple compression. This data was evaluated by a process of georeferencing for specific depths of 2.5, 5.0 and 7.5 meters for the SPT test and 2.30 and 3.30 meters for simple compression tests. Using geostatistical techniques (spatial interpolation) surfaces were modeled for the study area, in order to find information on locations where there have not been studies of soils

No presente trabalho medimos a resposta blastogênica de células de nódulos linfáticos de camundongos BALB/c inoculados com Leishmania mexicana, no decurso da infecção. Os resultados mostraram que os animais infectados exibem respostas blastogênicas normais nos nódulos linfáticos até vinte semanas depois da infecção. Daí por diante houve uma supressão gradual. A comparação da capacidade de resposta imunitária no baço e nos nódulos linfáticos mostrou respostas normais nesses nódulos várias semanas depois da ocorrência da supressão no baço. A supressão das respostas blastogênicas nos nódulos linfáticos estava relacionada a uma célula aderente de tipo macrófago, que suprimia ativamente as respostas proliferativas normais aos agentes mitogênicos.

In the present study we measured the blastogenic response of lymph node cells from BALB/c mice infected with Leishmania mexicana throughout the course of infection. Results showed that infected mice displayed normal blastogenic responses in the lymph nodes until twenty weeks of infection. Thereafter, there was a gradual suppression. Comparison of the immunoresponsiveness in the spleen and lymph nodes, revealed normal responses in the lymph nodes several weeks after suppression in the spleen had occurred. Suppression of blastogenic responses in the lymph nodes was related to an adherent macrophage-like cell which actively suppressed normal proliferative responses to mitogens.