Abstract Hypertrichosis and dental anomalies may occur alone or in combination in the spectrum of many syndromes. To identify genetic entities characterized by hypertrichosis and dental anomalies, a search was performed in the Mendelian Inheritance in Man database with the terms “hypertrichosis” or “hirsutism” and “tooth” or “dental abnormalities.” Nondependent androgen metabolism disturbances were classified as hypertrichosis. Genetic entities with hypertrichosis and dental anomalies were included in the study. Additional searches were performed in the PubMed and Orphanet databases, when necessary, in order to include data from scientific articles. An integrative analysis of the genes associated with the identified syndromes was conducted using STRING to characterize biological processes, pathways, and interactive networks. The p-values were subjected to the false discovery rate for the correction of multiple tests. Thirty-nine syndromes were identified, and dental agenesis was the most frequent dental anomaly present in 41.02% (n = 16) of the syndromes. Causative genes were identified in 33 out of 39 genetic syndromes. Among them, 39 genes were identified, and 38 were analyzed by STRING, which showed 148 biological processes and three pathways that were statistically significant. The most significant biological processes were the disassembly of the nucleosome (GO:0006337, p = 1.09e-06), chromosomal organization (GO:0051276, p = 1.09e-06) and remodeling of the chromatin (GO: 0006338, p = 7.86e-06), and the pathways were hepatocellular carcinoma (hsa05225, p = 5.77e-05), thermogenesis (hsa04714, p = 0.00019), and cell cycle (hsa04110, p = 0.0433). Our results showed that the identification of hypertrichosis and dental anomalies may raise the suspicion of one of the thirty-nine syndromes with both phenotypes. “hypertrichosis hirsutism “hirsutism tooth “tooth abnormalities. abnormalities study databases necessary articles networks pvalues values tests Thirtynine Thirty nine 4102 41 02 41.02 n 16 3 them 14 GO0006337, GO0006337 GO 0006337, 0006337 (GO:0006337 1.09e06, 109e06 e 1.09e 06 , 1 09e GO0051276, GO0051276 0051276, 0051276 (GO:0051276 1.09e06 1.09e-06 (GO 0006338 7.86e06, 786e06 7.86e 7 86e 7.86e-06) hsa05225, hsa05225 hsa (hsa05225 5.77e05, 577e05 5.77e 05 5 77e 5.77e-05) hsa04714, hsa04714 (hsa04714 0.00019, 000019 0.00019 0 00019 0.00019) hsa04110, hsa04110 (hsa04110 0.0433. 00433 0.0433 . 0433 0.0433) thirtynine thirty phenotypes 410 4 41.0 GO000633 000633 (GO:000633 09e06 109e0 109e GO005127 005127 (GO:005127 1.09e0 1.09e-0 86e06 7.86e06 786e0 786e 7.86e-06 hsa0522 (hsa0522 77e05 5.77e05 577e0 577e 5.77e-05 hsa0471 (hsa0471 00001 0.0001 0001 hsa0411 (hsa0411 0043 0.043 043 41. GO00063 00063 (GO:00063 09e0 GO00512 00512 (GO:00512 1.09e- 86e0 7.86e0 7.86e-0 hsa052 (hsa052 77e0 5.77e0 5.77e-0 hsa047 (hsa047 0000 0.000 000 hsa041 (hsa041 004 0.04 04 GO0006 0006 (GO:0006 GO0051 0051 (GO:0051 7.86e- hsa05 (hsa05 5.77e- hsa04 (hsa04 0.00 00 0.0 GO000 (GO:000 GO005 005 (GO:005 hsa0 (hsa0 0. GO00 (GO:00 (hsa GO0 (GO:0

Abstract: The aim of this study was to describe the oral health services offered by the Unified Health System in the northern macro-region of Minas Gerais, Brazil, during the COVID-19 pandemic. This was an observational, cross-sectional and descriptive study. Data collection took place between August and September 2020 through the completion of online questionnaires by oral health managers in the northern municipalities of Minas Gerais and by consultation of information available in the Special Epidemiological Bulletin Coronavirus North Macro-region n° 14. After collection, data were transferred to SPSS® (Statistical Package for the Social Sciences for Windows, version 24.0). Analyses were performed using frequency, mean, standard deviation and percentages. It was found that all included municipalities suspended elective treatments and maintained emergency dental care at all levels of care. In 62.5% of municipalities there were oral health professionals contaminated by COVID-19. Oral health teams implemented specific interventions to address the pandemic,with the most frequent being tele-orientation (74.7%), use of sanitary barriers (72%), and telemonitoring (68%). At the beginning of the pandemic, 62.5% of municipalities lacked personal protective equipment. Comsidering these results, it was found that the COVID-19 pandemic impacted the supply of dental services in northern Minas Gerais due to the suspension of elective care, contamination of professionals, lack of personal protective equipment, and development of new interventions. Thus, oral health teams had to adapt to new contexts of health interventionsto face COVID-19 and maintain dental care services.

Abstract We analyzed the distribution characteristics of the scientific production of Brazilian dentistry researchers of the Brazilian National Council for Scientific and Technological Development. The Lattes curriculum data of 211 researchers from Oral Pathology, Oral Surgery, and Oral Medicine fields were included (2018–2020). Over their academic career, 39 researchers published 7,555 papers (average, 175 articles/researcher); 3,876/7,555 papers were indexed in the Web of Science. During 2018–2020, 1,440/7,555 (19%) papers were published. Brazilian dental researchers contribute significantly to international research by participating in scientific journals’ editorial boards, evaluating research promotion agencies, training researchers, and contributing to scientific and technological development.

Abstract: Kawasaki disease (KD) is a vasculitis with predilection for coronary arteries. Due to a lack of reliable confirmatory laboratory tests, the diagnosis of KD is based on a characteristic pattern of clinical findings that appear in a typical temporal sequence. The diagnostic criteria have been periodically modified and the American Heart Association has proposed the most recent guidelines for its diagnosis. However, patients may have incomplete or atypical forms of KD and diagnosis can often be difficult. Because oropharyngeal manifestations are a common and important feature for diagnosing KD and recent studies have hypothesized a possible association between KD and the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in this review we highlight the importance of dentists in the diagnosis of KD and its potential association with SARS-CoV-2.