SUMMARY OBJECTIVE: The Glasgow prognosis score is a simple parameter calculated using serum levels of albumin and C-reactive protein. The aim of this study was to examine whether this parameter may predict ischemic stroke in patients with infective endocarditis. METHODS: A total of 80 patients who were diagnosed with definitive infective endocarditis according to Duke criteria between 2016 and 2023 were included in the study. Glasgow prognosis score was based on serum levels of albumin and C-reactive protein. In imaging methods, patients were divided into two groups according to whether they had a stroke or not. These two groups were compared in terms of biochemical parameters, and infective endocarditis findings on echocardiography and Glasgow prognosis score. RESULTS: We found that the results were statistically similar except for serum C-reactive protein (Group 1: 54.9±71.1 and Group 2: 39±70.7; p=0.03), neutrophil (Group 1: 19.8±10.8*109/L and Group 2: 13.3±7.3*109/L; p=0.014), albumin (Group 1: 2.3±0.6 and Group 2: 2.8±0.5; p=0.03), and Glasgow prognosis score (Group 1: median 2, min.–max. (1–2) and Group 2: median 1, min.–max. (0–1); p=0.004). In the receiver operating characteristics analysis, Glasgow prognosis score had 82.4% sensitivity and 58.3% specificity in predicting ischemic stroke if the Glasgow prognosis score cutoff was ≥1. In multivariate logistic regression analysis, chronic renal failure [odds ratio (OR): 1.098; 95% confidence interval: 1.054–1.964; p=0.044], age (OR: 1.050; 95%CI 1.006–1.096; p=0.024), and Glasgow prognosis score (OR: 0.695; 95%CI 0.411–0.949; p=0.035) were independent variables in predicting ischemic stroke. CONCLUSION: High Glasgow prognosis score is an independent predictor of ischemic stroke in patients with infective endocarditis. Glasgow prognosis score, determined using albumin and C-reactive protein levels, is a simple and practical index for predicting the prognosis of patients hospitalized with infective endocarditis. OBJECTIVE Creactive C reactive METHODS 8 201 202 methods not parameters RESULTS 1 549711 54 9 71 54.9±71. 2 39±70.7 39707 39 70 7 p=0.03, p003 p p=0.03 , 0 03 p=0.03) 198108109L L 19 10 109 13.3±7.3*109/L 13373109L 13 3 p=0.014, p0014 p=0.014 014 p=0.014) 2306 6 2.3±0. 2.8±0.5 2805 5 minmax min max min.–max 1–2 12 (1–2 0–1 01 (0–1) p=0.004. p0004 p=0.004 . 004 p=0.004) analysis 824 82 4 82.4 583 58 58.3 ≥1 odds OR (OR) 1.098 1098 098 95 interval 1.054–1.964 10541964 054 964 p=0.044, p0044 p=0.044 044 p=0.044] (OR 1.050 1050 050 95CI CI 1.006–1.096 10061096 006 096 p=0.024, p0024 p=0.024 024 p=0.024) 0.695 0695 695 0.411–0.949 04110949 411 949 p=0.035 p0035 035 CONCLUSION 20 54971 54.9±71 39±70. 3970 p00 p=0.0 p001 p=0.01 230 2.3±0 2.8±0. 280 1– (1– 0– (0–1 p000 p=0.00 00 82. 58. ≥ 1.09 09 1.054–1.96 1054196 05 96 p004 p=0.04 04 1.05 105 1.006–1.09 1006109 p002 p=0.02 02 0.69 069 69 0.411–0.94 0411094 41 94 5497 54.9±7 39±70 397 p0 p=0. 23 2.3± 2.8±0 28 (1 (0– 1.0 1.054–1.9 105419 1.006–1.0 100610 0.6 06 0.411–0.9 041109 549 54.9± 39±7 p=0 2.3 2.8± ( (0 1. 1.054–1. 10541 1.006–1. 10061 0. 0.411–0. 04110 54.9 39± p= 2. 2.8 1.054–1 1054 1.006–1 1006 0.411–0 0411 54. 1.054– 1.006– 100 0.411– 041 1.054 1.006 0.411 1.00 0.41 0.4

SUMMARY OBJECTIVE: Sudden cardiac death or arrest describes an unexpected cardiac cause-related death or arrest that occurs rapidly out of the hospital or in the emergency room. This study aimed to reveal the relationship between coronary angiographic findings and cardiac death secondary to acute ST-elevation myocardial infarction. MATERIALS AND METHODS: Patients presenting with acute ST-elevation myocardial infarction complicated with cardiac arrest were included in the study. The severity of coronary artery disease, coronary chronic total occlusion, coronary collateral circulation, and blood flow in the infarct-related artery were recorded. Patients were divided into two groups, namely, deaths secondary to cardiac arrest and survivors of cardiac arrest. RESULTS: A total of 161 cardiac deaths and 42 survivors of cardiac arrest were included. The most frequent (46.3%) location of the culprit lesion was on the proximal left anterior descending artery. The left-dominant coronary circulation was 59.1%. There was a difference in the SYNTAX score (16.3±3.8 vs. 13.6±1.9; p=0.03) and the presence of chronic total occlusion (19.2 vs. 0%; p=0.02) between survivors and cardiac deaths. A high SYNTAX score (OR: 0.38, 95%CI: 0.27–0.53, p<0.01) was determined as an independent predictor of death secondary to cardiac arrest. CONCLUSION: The chronic total occlusion presence and SYNTAX score may predict death after cardiac arrest secondary to ST-elevation myocardial infarction. OBJECTIVE causerelated cause related room STelevation ST elevation METHODS disease infarctrelated infarct recorded groups namely RESULTS 16 4 46.3% 463 46 3 (46.3% leftdominant dominant 591 59 1 59.1% 16.3±3.8 16338 8 (16.3±3. vs 13.6±1.9 13619 13 6 9 p=0.03 p003 p 0 03 19.2 192 19 2 (19. 0% p=0.02 p002 02 OR (OR 038 38 0.38 95%CI 95CI CI 95 027053 27 53 0.27–0.53 p<0.01 p001 01 CONCLUSION 46.3 (46.3 5 59.1 16.3±3. 1633 (16.3±3 13.6±1. 1361 p=0.0 p00 19. (19 0.3 02705 0.27–0.5 p<0.0 46. (46. 59. 16.3±3 163 (16.3± 13.6±1 136 p=0. p0 (1 0. 0270 0.27–0. p<0. (46 16.3± (16.3 13.6± p=0 ( 027 0.27–0 p<0 (4 16.3 (16. 13.6 p= 0.27– p< 16. (16 13. 0.27 0.2

SUMMARY OBJECTIVE: Coronary artery disease (CAD) is frequent, but coronary slow flow (CSF) is a less common cardiovascular disease with a significant risk of mortality and morbidity. Endocan is a proinflammatory glycopeptide that has been investigated in cardiovascular diseases as well as some inflammatory diseases in recent years. We planned to compare the levels of endocan in both CAD and CSF in a similar population and examine the relationship of endocan with additional clinical variables. MATERIALS AND METHODS: In the trial, we included 169 consecutive subjects having a coronary angiography indication. According to the results of coronary angiography, 58 people were included in the CAD group, 52 were in the CSF group, and 59 people were in the control group. The control group includes those who did not have any lesions in their epicardial coronary arteries. Thrombolysis in myocardial infarction (TIMI)-frame counts (TFC) were calculated for all patients. RESULTS: Notably, 2.6% of the population in our study had CSF. Both the CAD (555±223 pg/mL) and CSF (559±234 pg/mL) groups had higher endocan levels than the control group (331±252 pg/mL) (p<0.001). There were similar endocan levels between the CAD and CSF groups. Endocan levels were shown to be favorably associated with mean TFC (r=0.267; p0.001). Serum endocan levels (particularly those above 450 pg/mL) and the presence of hyperlipidemia were the most important predictors of both CAD and CSF. CONCLUSION: Endocan levels are higher in CAD and CSF patients than in those with normal coronary arteries. OBJECTIVE (CAD frequent (CSF morbidity years variables METHODS trial 16 indication 5 arteries TIMIframe TIMI frame (TFC RESULTS Notably 26 2 6 2.6 555±223 555223 555 223 (555±22 pg/mL pgmL pg mL 559±234 559234 559 234 (559±23 331±252 331252 331 252 (331±25 p<0.001. p0001 p p<0.001 . 0 001 (p<0.001) r=0.267 r0267 r 267 (r=0.267 p0.001. p0.001 p0 p0.001) particularly 45 CONCLUSION 1 2. 555±22 55522 55 22 (555±2 559±23 55923 23 (559±2 331±25 33125 33 25 (331±2 p000 p<0.00 00 (p<0.001 r=0.26 r026 (r=0.26 p0.00 4 555±2 5552 (555± 559±2 5592 (559± 331±2 3312 3 (331± p00 p<0.0 (p<0.00 r=0.2 r02 (r=0.2 p0.0 555± (555 559± (559 331± (331 p<0. (p<0.0 r=0. r0 (r=0. p0. (55 (33 p<0 (p<0. r=0 (r=0 (5 (3 p< (p<0 r= (r= ( (p< (r (p

SUMMARY BACKGROUND: The simplified Selvester QRS score is a parameter for estimating myocardial damage in ST-elevation myocardial infarction. ST-elevation myocardial infarction leads to varying degrees of impairment in left ventricular systolic and diastolic function. Myocardial performance index is a single parameter that can predict combined left ventricular systolic and diastolic performance. OBJECTIVE: We investigated the relationship between Selvester score and myocardial performance index in patients undergoing primary percutaneous coronary intervention for acute anterior myocardial infarction. METHODS: The study included 58 patients who underwent primary percutaneous coronary intervention for acute anterior myocardial infarction. Selvester score of all patients was also calculated at 72 h. Patients were categorized into two groups according to the Selvester score. Those with a score <6 (low score) were considered group 1 and those with a score ≥6 (high score) were considered group 2. RESULTS: When compared with group 1, patients in group 2 were older (p=0.01) and had lower left ventricular ejection fractions (50.3±4 vs. 35.6±6.9, p=0.001), and conventional myocardial performance index (0.52±0.06 vs. 0.69±0.08, p=0.001), lateral tissue Doppler-derived myocardial performance index (0.57±0.08 vs. 0.72±0.08, p=0.001), and septal tissue Doppler-derived myocardial performance index (0.62±0.07 vs. 0.76±0.08, p=0.001) were higher. There was a high correlation between lateral tissue Doppler-derived myocardial performance index and conventional myocardial performance index and Selvester score (r=0.80, p<0.001; r=0.86, p<0.001, respectively) and a moderate correlation between septal tissue Doppler-derived myocardial performance index and Selvester score (r=0.67, p<0.001). CONCLUSIONS: The post-procedural Selvester score can predict lateral tissue Doppler-derived myocardial performance index and conventional myocardial performance index with high sensitivity and acceptable specificity in patients undergoing primary percutaneous coronary intervention for acute anterior myocardial infarction. BACKGROUND STelevation ST elevation function OBJECTIVE METHODS 5 7 h 6 < low ≥ RESULTS p=0.01 p001 p 0 01 (p=0.01 50.3±4 5034 50 3 4 (50.3± vs 35669 35 9 35.6±6.9 p=0.001, p0001 p=0.001 , 001 0.52±0.06 052006 52 06 (0.52±0.0 069008 69 08 0.69±0.08 Dopplerderived Doppler derived 0.57±0.08 057008 57 (0.57±0.0 072008 0.72±0.08 0.62±0.07 062007 62 07 (0.62±0.0 076008 76 0.76±0.08 higher r=0.80, r080 r 80 (r=0.80 p<0.001 r086 86 r=0.86 respectively r=0.67, r067 67 (r=0.67 p<0.001. . p<0.001) CONCLUSIONS postprocedural post procedural p=0.0 p00 (p=0.0 50.3± 503 (50.3 3566 35.6±6. p000 p=0.00 00 0.52±0.0 05200 (0.52±0. 06900 0.69±0.0 0.57±0.0 05700 (0.57±0. 07200 0.72±0.0 0.62±0.0 06200 (0.62±0. 07600 0.76±0.0 r=0.80 r08 8 (r=0.8 p<0.00 r=0.8 r=0.67 r06 (r=0.6 p=0. p0 (p=0. 50.3 (50. 356 35.6±6 0.52±0. 0520 (0.52±0 0690 0.69±0. 0.57±0. 0570 (0.57±0 0720 0.72±0. 0.62±0. 0620 (0.62±0 0760 0.76±0. r0 (r=0. p<0.0 r=0. r=0.6 p=0 (p=0 50. (50 35.6± 0.52±0 052 (0.52± 069 0.69±0 0.57±0 057 (0.57± 072 0.72±0 0.62±0 062 (0.62± 076 0.76±0 (r=0 p<0. r=0 p= (p= (5 35.6 0.52± 05 (0.52 0.69± 0.57± (0.57 0.72± 0.62± (0.62 0.76± (r= p<0 r= (p ( 35. 0.52 (0.5 0.69 0.57 0.72 0.62 (0.6 0.76 (r p< 0.5 (0. 0.6 0.7 0. (0

SUMMARY OBJECTIVE: In this article, we investigated the association of chromogranin A with coronary artery disease. METHODS: Biochemical parameters and chromogranin A levels obtained from peripheral blood samples during coronary angiography were analyzed in 90 patients. Patients were classified into two groups, namely, SYNergy between PCI with TAXUS and Cardiac Surgery score ≥1 (n=45) and SYNergy between PCI with TAXUS and Cardiac Surgery score=0 (n=45). This is a cross-sectional, prospective study. RESULTS: Serum chromogranin A levels were significantly higher in the group with SYNergy between PCI with TAXUS and Cardiac Surgery score ≥1 compared to the group with SYNergy between PCI with TAXUS and Cardiac Surgery score=0 (1381.5±418.9 ng/mL and 1121.2±290.7 ng/mL, respectively; p=0.002). Serum chromogranin A levels were correlated with SYNergy between PCI with TAXUS and Cardiac Surgery score (r=0.556, p<0.04). ROC analysis showed that the area under the curve for serum chromogranin A levels was 0.687 (p=0.007), and the best cutoff value of 1,131 ng/mL had a sensitivity of 67% and a specificity of 65% for the prediction of coronary artery disease. CONCLUSION: Serum chromogranin A levels were increased in coronary artery disease patients with SYNergy between PCI with TAXUS and Cardiac Surgery score ≥1. Increasing serum chromogranin A levels are proportional to the SYNergy between PCI with TAXUS and Cardiac Surgery score. OBJECTIVE article METHODS 9 groups namely 1 ≥ n=45 n45 n 45 (n=45 score0 0 score= n=45. . crosssectional, crosssectional cross sectional, sectional cross-sectional study RESULTS 1381.5±418.9 138154189 1381 5 418 (1381.5±418. ngmL ng mL 112122907 1121 2 290 7 1121.2±290. respectively p=0.002. p0002 p p=0.002 002 p=0.002) r=0.556, r0556 r 556 (r=0.556 p<0.04. p004 p<0.04 04 p<0.04) 0687 687 0.68 p=0.007, p0007 p=0.007 , 007 (p=0.007) 1131 131 1,13 67 65 CONCLUSION n=4 n4 4 (n=4 1381.5±418. 13815418 138 41 (1381.5±418 11212290 112 29 1121.2±290 p000 p=0.00 00 r=0.556 r055 55 (r=0.55 p00 p<0.0 068 68 0.6 (p=0.007 113 13 1,1 6 n= (n= 1381.5±418 1381541 (1381.5±41 1121229 11 1121.2±29 p=0.0 r=0.55 r05 (r=0.5 p0 p<0. 06 0. (p=0.00 1, (n 1381.5±41 138154 (1381.5±4 112122 1121.2±2 p=0. r=0.5 r0 (r=0. p<0 (p=0.0 1381.5±4 13815 (1381.5± 11212 1121.2± p=0 r=0. (r=0 p< (p=0. 1381.5± (1381.5 1121.2 p= r=0 (r= (p=0 1381.5 (1381. 1121. r= (r (p= 1381. (1381 (p (138 (13 (1 (

Abstract Background Coronary slow flow (CSF) refers to delayed distal vessel opacification in the absence of epicardial coronary artery stenosis. The etiopathogenic mechanism of CSF is still unclear. Objectives This study investigates the relationship between CSF and the triglyceride-glucose (TyG) index. Methods The study sample consisted of 118 CSF patients and 105 patients with normal coronary flow (NCF). The coronary flow rate was measured via the Thrombolysis in Myocardial Infarction (TIMI) frame count (TFC) method in all patients. The TyG index was calculated as the logarithm of the [fasting triglyceride (mg/dL)×fasting glucose (mg/dL)]/2 value. A significance level of < 0.05 was adopted as statistically significant. Results The TyG index, low-density lipoprotein (LDL), body mass index (BMI), neutrophil-to-lymphocyte ratio (NLR) and TFC values, male ratio, and the ratio of smokers were higher, whereas high-density lipoprotein (HDL) levels were significantly lower in the CSF group compared to the NCF group (p<0,05). The correlation analysis revealed that CSF was significantly correlated with TyG index, BMI, NLR, and HDL values. The strongest of these correlations was between CSF and TyG index (r= 0.57, p<0.001). Additionally, the multivariate analysis revealed that TyG index, BMI, NLR ratio, and male gender were independent predictors for CSF (p<0.05). Receiver operating characteristic (ROC) curve analysis indicated that a cut-off value of ≥ 9.28 for the TyG index predicted CSF with a sensitivity of 78% and a specificity of 78.1% [Area under the curve (AUC): 0.868 and 95% Confidence Interval (CI): 0.823-0.914]. Conclusion The findings of this study revealed a very strong relationship between CSF and TyG index. (CSF stenosis unclear triglycerideglucose (TyG 11 10 NCF. . (NCF) TIMI (TIMI (TFC fasting mg/dL×fasting mgdLfasting mg/dL ×fasting mg dL mg/dL/2 mgdL2 mgdL /2 2 (mg/dL)]/ 005 0 05 0.0 significant lowdensity low density LDL, LDL , (LDL) BMI (BMI) neutrophiltolymphocyte neutrophil lymphocyte (NLR values higher highdensity high (HDL p<0,05. p005 p p<0,05 (p<0,05) r= r (r 057 57 0.57 p<0.001. p0001 p<0.001 001 p<0.001) Additionally p<0.05. p<0.05 (p<0.05) ROC (ROC cutoff cut off 928 9 28 9.2 78 781 1 78.1 Area AUC (AUC) 0868 868 0.86 95 CI (CI) 0.8230.914. 08230914 0.823 0.914 823 914 0.823-0.914] (NCF mg/dL/ / (mg/dL)] 00 0. (LDL (BMI p00 p<0,0 (p<0,05 5 0.5 p000 p<0.00 p<0.0 (p<0.05 92 9. 7 78. (AUC 086 86 0.8 (CI 8230 0.8230.914 0823091 0823 0.82 0914 0.91 82 91 0.823-0.914 (mg/dL) p0 p<0, (p<0,0 p<0. (p<0.0 08 8 0.8230.91 082309 082 091 0.9 0.823-0.91 (mg/dL p<0 (p<0, (p<0. 0.8230.9 08230 09 0.823-0.9 p< (p<0 0.8230. 0.823-0. (p< 0.8230 0.823-0 (p 0.823-

Resumo Fundamento O fluxo lento coronariano (FLC) refere-se à opacificação retardada dos vasos distais na ausência de estenose da artéria coronária epicárdica. O mecanismo etiopatogênico do FLC ainda não está claro. Objetivos Este estudo investiga a relação entre o FLC e o índice de triglicerídeos-glicose (TyG). Métodos A amostra do estudo consistiu de 118 pacientes com FLC e 105 pacientes com fluxo coronariano normal (FCN). A taxa de fluxo coronariano foi medida por medio do método de contagem de quadros (TFC) Thrombolysis in Myocardial Infarction (TIMI) em todos os pacientes. O índice TyG foi calculado como o logaritmo do valor [triglicerídeos em jejum (mg/dL)×glicose em jejum (mg/dL)]/2. Adotou-se como estatisticamente significativo o nível de significância < 0,05. Resultados O índice TyG, lipoproteína de baixa densidade (LDL), índice de massa corporal (IMC), relação neutrófilo-linfócito (RNL) e valores de TFC, proporção masculina e proporção de fumantes foram maiores, enquanto os níveis de lipoproteína de alta densidade (HDL) foram significativamente menores no grupo FLC em comparação com o grupo FNC (p<0,05). A análise de correlação revelou que o FLC estava significativamente correlacionado com os valores do índice TyG, IMC, RNL e HDL. A mais forte dessas correlações foi entre o FLC e o índice TyG (r= 0,57, p<0,001). Além disso, a análise multivariada revelou que o índice TyG, IMC, razão RNL e sexo masculino foram preditores independentes para FLC (p<0,05). A análise da curva ROC (Receiver Operating Characteristic) indicou que um valor de corte ≥ 9,28 para o índice TyG previu FLC com sensibilidade de 78% e especificidade de 78,1% [Área sob a curva (AUC): 0,868 e 95% intervalo de confiança (IC): 0,823-0,914]. Conclusão Os achados deste estudo revelaram uma relação muito forte entre o FLC e o índice TyG. (FLC referese refere se epicárdica claro triglicerídeosglicose triglicerídeos glicose . (TyG) 11 10 FCN. FCN (FCN) TFC (TFC TIMI (TIMI mg/dL×glicose mgdLglicose mg/dL ×glicose mg dL mg/dL/2. mgdL2 mgdL /2. 2 (mg/dL)]/2 Adotouse Adotou 005 0 05 0,05 LDL, LDL , (LDL) IMC (IMC) neutrófilolinfócito neutrófilo linfócito (RNL maiores HDL (HDL p<0,05. p005 p p<0,05 (p<0,05) r= r (r 057 57 0,57 p<0,001. p0001 p<0,001 001 p<0,001) disso Receiver Characteristic 928 9 28 9,2 78 781 1 78,1 Área AUC (AUC) 0868 868 0,86 95 IC (IC) 0,8230,914. 08230914 0,823 0,914 823 914 0,823-0,914] (TyG (FCN mg/dL/2 /2 (mg/dL)]/ 00 0,0 (LDL (IMC p00 p<0,0 (p<0,05 5 0,5 p000 p<0,00 92 9, 7 78, (AUC 086 86 0,8 (IC 8230 0,8230,914 0823091 0823 0,82 0914 0,91 82 91 0,823-0,914 mg/dL/ / (mg/dL)] 0, p0 p<0, (p<0,0 08 8 0,8230,91 082309 082 091 0,9 0,823-0,91 (mg/dL) p<0 (p<0, 0,8230,9 08230 09 0,823-0,9 (mg/dL p< (p<0 0,8230, 0,823-0, (p< 0,8230 0,823-0 (p 0,823-

SUMMARY OBJECTIVE: In our study, we aimed to find simple, useful biomarkers in patients with non-ST elevation myocardial infarction to predict coronary artery severity. METHODS: Between May 2022 and December 2022, patients diagnosed with non-ST elevation myocardial infarction according to the European cardiology guidelines were included in our study. The Synergy between PCI with Taxus and Cardiac Surgery score was calculated to determine the severity of coronary artery disease. These patients were classified into two groups according to Synergy between PCI with Taxus and Cardiac Surgery≥23 and Synergy between PCI with Taxus and Cardiac Surgery<23 scores. Biochemical markers such as platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio were studied in blood tests taken before coronary angiography in patients diagnosed with non-ST elevation myocardial infarction according to current guidelines. These two groups were compared in terms of the data obtained. RESULTS: There were 281 patients in group 1 and 67 patients in group 2. There was no significant difference between the two groups in terms of demographic data such as age and gender. Platelet-to-lymphocyte ratio [group 1=125 (26–134) and group 2=156 (73–293); p=0.001] and neutrophil-to-lymphocyte ratio [group 1=2.71 (1.3–30.2) and group 2=3.2 (2.1–32.1); p=0.002] were higher in the group of patients with a Synergy between PCI with Taxus and Cardiac Surgery score of <23, while lymphocyte-to-monocyte ratio [group 1=3.6 (0.56–11) and group 2=3.4 (0.64–5.75); p=0.017] was lower in group 2. CONCLUSION: We observed that elevated platelet-to-lymphocyte and neutrophil-to-lymphocyte ratios showed coronary artery severity. Multivessel disease and chronic total occlusion rates were observed to be higher in patients with high platelet-to-lymphocyte and neutrophil-to-lymphocyte ratios. OBJECTIVE study simple nonST non ST METHODS 202 Surgery23 23 Surgery≥2 Surgery<2 scores platelettolymphocyte platelet lymphocyte neutrophiltolymphocyte neutrophil obtained RESULTS 28 6 2 gender Platelettolymphocyte Platelet 1125 125 1=12 26–134 26134 26 134 (26–134 2156 156 2=15 73–293 73293 73 293 (73–293) p=0.001 p0001 p 0 001 1271 71 1=2.7 1.3–30.2 13302 3 30 (1.3–30.2 232 2=3. 2.1–32.1 21321 32 (2.1–32.1) p=0.002 p0002 002 <23 lymphocytetomonocyte monocyte 136 1=3. 0.56–11 05611 56 11 (0.56–11 234 4 0.64–5.75 064575 64 5 75 (0.64–5.75) p=0.017 p0017 017 CONCLUSION 20 Surgery2 Surgery≥ Surgery< 112 12 1=1 26–13 2613 13 (26–13 215 15 2=1 73–29 7329 7 29 (73–293 p=0.00 p000 00 127 1=2. 1.3–30. 1330 (1.3–30. 2=3 2.1–32. 2132 (2.1–32.1 <2 1=3 0.56–1 0561 (0.56–1 0.64–5.7 06457 (0.64–5.75 p=0.01 p001 01 1= 26–1 261 (26–1 21 2= 73–2 732 (73–29 p=0.0 p00 1=2 1.3–30 133 (1.3–30 2.1–32 213 (2.1–32. < 0.56– 056 (0.56– 0.64–5. 0645 (0.64–5.7 26– (26– 73– (73–2 p=0. p0 1.3–3 (1.3–3 2.1–3 (2.1–32 0.56 05 (0.56 0.64–5 064 (0.64–5. (26 (73– p=0 1.3– (1.3– 2.1– (2.1–3 0.5 (0.5 0.64– 06 (0.64–5 (2 (73 p= 1.3 (1.3 2.1 (2.1– 0. (0. 0.64 (0.64– ( (7 1. (1. (2.1 (0 0.6 (0.64 (1 (2. (0.6