ABSTRACT Proper waste management is a major worldwide concern; waste is disposed of directly into the environment, affecting water, soil and air quality. The development and production of green energy sources is strongly encouraged in modern society. The aim of this study, in accordance with Sustainable Development Goals (SDGs) 1, 2 and 7 of the 2030 Agenda of the UN, is to combine the correct disposal of animal waste with the generation of energy to mitigate the energy insecurity of families in an extremely vulnerable semi-arid region in the north-east of the country using biodigesters. To this end, a conceptual proposal was drawn up for a low-cost, easy-to-maintain and easy-to-use biodigester. A small-scale prototype was used to assess its operation by evaluating the main factors that affect biogas production (pH, temperature and the biomass properties: total solids, fixed solids, volatile solids, concentration of volatile fatty acids and C/N ratio). Evaluation of the test prototype gave satisfactory results that corroborate other studies and make it possible to propose an economically viable and efficient full-scale biodigester for biogas production. concern environment water quality society study SDGs (SDGs 1 203 UN semiarid semi arid northeast north east biodigesters end lowcost, lowcost low cost, cost low-cost easytomaintain easy maintain easytouse use smallscale small scale pH, pH (pH properties solids CN C N ratio. ratio . ratio) fullscale full 20

ABSTRACT Purpose: This prospective, randomized, unmasked, clinical trial aimed to report the visual outcomes of cataract surgery on both eyes versus cataract surgery on one eye in Brazilian patients. Methods: This study included patients with bilateral cataracts and binocular visual acuity worse than or equal to 0.3 logarithm of the minimum angle of resolution. The patients were randomly assigned to undergo surgery on one (Control Group) or both eyes (one eye at a time; Intervention Group). Postoperatively, self-reported visual function using Catquest-9SF (primary outcome measure), binocular visual acuity, stereopsis, and ocular dominance (secondary outcome measures) were compared. Results: A total of 151 patients (77 and 148 eyes in the Control and Intervention Groups, respectively) completed the follow-up. Patients who underwent surgery on both eyes exhibited significantly better self-reported visual function (p=0.036) and stereopsis (p=0.026) than those who underwent surgery on one eye. Binocular visual acuity and ocular dominance did not affect the group comparisons. Conclusions: Surgery on both eyes resulted in significantly better self-reported visual function and stereopsis than surgery on one eye. Purpose prospective randomized unmasked Methods 03 0 3 0. resolution Group time Group. . Postoperatively selfreported self reported Catquest9SF CatquestSF Catquest 9SF SF primary measure, measure , measure) secondary measures compared Results 15 77 (7 14 Groups respectively followup. followup follow up. up follow-up p=0.036 p0036 p 036 (p=0.036 p=0.026 p0026 026 (p=0.026 comparisons Conclusions 1 7 ( p=0.03 p003 (p=0.03 p=0.02 p002 02 (p=0.02 p=0.0 p00 (p=0.0 p=0. p0 (p=0. p=0 (p=0 p= (p= (p

RESUMO Objetivo: Descrever como aplicativos de smartphone podem contribuir para o gerenciamento de quadros de epilepsia em crianças e adolescentes. Fontes de dados: Trata-se de uma revisão integrativa realizada nas bases de dados Medline; PubMed e SciELO, com base nos descritores “epilepsy” e “smartphone”. Foram incluídos estudos originais publicados entre 2017–2023 em português ou inglês que respondessem à pergunta de investigação. Teses e dissertações, estudos duplicados, revisões de literatura e estudos que não responderam à questão de pesquisa foram excluídos. Síntese dos dados: Foram localizados 178 estudos, dos quais seis foram selecionados para compor esta revisão. A amostra incluiu 731 participantes (631 infantojuvenis com epilepsia e 100 cuidadores). Os aplicativos permitem a coleta da frequência de convulsões; momento e o tipo de crise; lembretes para a administração de medicamentos; e informações sobre a qualidade do sono, sendo capazes de armazenar esses dados para profissionais da saúde, cuidadores e usuários acompanharem a evolução do quadro. Conclusões: O uso de aplicativos no manejo das convulsões de crianças e adolescentes com epilepsia apresenta resultados promissores ao promoverem um monitoramento contínuo e personalizado. Novos estudos são necessários para otimizar os resultados benéficos e superar desafios. Objetivo Tratase Trata se Medline SciELO epilepsy “epilepsy smartphone. . “smartphone” 20172023 2017 2023 2017–202 investigação dissertações duplicados excluídos 17 73 631 (63 10 cuidadores. cuidadores) crise medicamentos sono saúde quadro Conclusões personalizado desafios “smartphone 2017202 201 202 2017–20 1 7 63 (6 201720 20 2017–2 6 ( 20172 2 2017–

ABSTRACT Objective: To describe how smartphone applications can contribute to the management of epilepsy in children and adolescents. Data source: This is an integrative review conducted on the Medline, PubMed, and SciELO databases, based on the descriptors “epilepsy” and “smartphone.” Original studies published between 2017–2023 in Portuguese or English that addressed the research question were included. Theses and dissertations, duplicate studies, literature reviews, and studies that did not answer the research question were excluded. Data synthesis: A total of 178 studies were located, of which six were selected for this review. The sample included 731 participants (631 children and adolescents with epilepsy and 100 caregivers). The applications allow for the collection of seizure frequency; timing and type of crisis; reminders for medication administration; and information about sleep quality. They can store these data for healthcare professionals, caregivers, and users to monitor the progress of the condition. Conclusions: The use of applications in managing seizures in children and adolescents with epilepsy shows promising results by promoting continuous and personalized monitoring. Further studies are needed to optimize beneficial outcomes and overcome challenges. Objective source Medline PubMed databases “epilepsy smartphone. “smartphone. 20172023 2017 2023 2017–202 dissertations reviews excluded synthesis 17 located 73 631 (63 10 caregivers. caregivers . caregivers) frequency crisis administration quality professionals condition Conclusions monitoring challenges “smartphone 2017202 201 202 2017–20 1 7 63 (6 201720 20 2017–2 6 ( 20172 2 2017–

Cupuaçu (Theobroma grandiflorum Schum.) is an Amazonian fruit rich in antioxidants potential due to its phenolic compounds. Its seeds produce cupulate, a chocolate-like product, and the residue remains rich in biocompounds. This study aimed to optimize and compare microwave-assisted (MAE) and high pressure/temperature extraction (HPTE) of polyphenolic and flavonoid compounds from cupuaçu seed by-products. A Box-Behnken 33 factorial design assessed the influence of extraction time, solid/liquid ratio, and ethanol concentration. Responses included total polyphenol content, total flavonoid content, and anti-radical power via the ABTS (2,2-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid) method. In optimum conditions, MAE had the highest total polyphenol content and HPTE for flavonoids. Optimal conditions for both methods were 65% (m/v) ethanol concentration, 45 min extraction time, and 0.03 g mL−1 solid/liquid ratio. MAE and HPTE achieved greater recovery of (−)-epicatechin and (−)-epigallocatechin-3-gallate compared to percolation. Both techniques proved viable for recovering polyphenols from cupuaçu seed by-products, in less time and with less solvent. Thus, cupuaçu by-products can be a sustainable and functional food source, with MAE and HPTE providing high yields and quality extracts rich in polyphenols. Theobroma Schum. Schum cupulate chocolatelike chocolate like product biocompounds microwaveassisted microwave assisted (MAE pressuretemperature pressure temperature (HPTE byproducts. byproducts by products. products BoxBehnken Box Behnken 3 solidliquid solid liquid ratio concentration antiradical anti radical 2,2azinobis3ethylbenzothiazoline6sulphonic 22azinobis3ethylbenzothiazoline6sulphonic azinobisethylbenzothiazolinesulphonic 2,2 azino bis ethylbenzothiazoline 6 sulphonic 2 acid method flavonoids 65 m/v mv m v (m/v 4 003 0 03 0.0 mL1 mL 1 mL− −epicatechin epicatechin − −epigallocatechin3gallate epigallocatechin3gallate epigallocatechingallate epigallocatechin gallate percolation byproducts, products, solvent Thus source 2azinobis3ethylbenzothiazoline6sulphonic azinobis 22 2, 00 0.

ABSTRACT Biochar can promote crop production and soil quality. However, its characteristics depend on the waste used in its production and its effects may vary according to the species being cultivated and the management adopted. The aim of this study was to evaluate the application of biochar from animal waste on soil quality and the agronomic characteristics of the cowpea. An experiment was set up to test three types of biochar (bovine-BB, swine-SB and poultry-BP), with added fertiliser (BBF, SBF and BPF) and two control treatments, including the addition of calcium magnesium oxide (CT) and calcium magnesium oxide with fertiliser (CTF), giving a total of eight treatments with four replications. There was a respective increase of up to 102.94%, 1048%, 1560% and 360.22% in stem diameter, number of pods, number of grains per pod and stem dry matter from adding the biochar. The poultry biochar increased each of the above parameters even with no added fertiliser. There was no difference in basal soil respiration or β-glucosidase enzyme activity, whereas organic carbon (TOC), total nitrogen (TN), microbial carbon and soil labile carbon were greater with biochar. BBF gave the highest TOC content (24.40 g kg-1), while BP and BPF increased TN by around 61%. The application of biochar + fertiliser contributed to an average reduction of 56% in the soil metabolic quotient. Poultry biochar favoured both the agronomic characteristics of the cowpea and soil quality, while bovine biochar showed more marked results with the addition of fertiliser. However adopted bovineBB, bovineBB BB, BB (bovine-BB swineSB swine SB poultryBP, poultryBP , poultry-BP) BBF, (BBF CT (CT CTF, CTF (CTF) replications 10294 102 94 102.94% 1048 1048% 1560 36022 360 22 360.22 diameter pods βglucosidase β glucosidase activity TOC, (TOC) TN, (TN) 24.40 2440 24 40 (24.4 kg1, kg1 kg 1 kg-1) 61 61% 56 quotient poultry-BP (CTF 1029 10 9 102.94 104 156 3602 36 2 360.2 (TOC (TN 24.4 244 4 (24. kg-1 6 5 102.9 15 3 360. 24. (24 kg- 102. (2 (

Groundwater is considered an important source of water aid for human consumption. However, this water can be contaminated by impurities, such contamination spots that might reach the water tables. The aim of this study was to investigate the quality of shallow groundwater in Flores neighborhood, located in the municipality of Benevides, within Belém metropolitan region, State of Pará, Brazil. Recommendations described in Standard Methods for Examination of Water and Wastewater were followed at the time to determine physical-chemical parameters such as potential hydrogen (pH), electrical conductivity (EC), total dissolved solids (TDS), apparent color, turbidity, total hardness (TH), ions and trace elements. Multivariate statistical analysis has shown that most predictive water-quality parameters set for human consumption are associated with natural events involving weathering and leaching processes. Nevertheless, parameters of nitrate, phosphate, EC, TDS and pH are also influenced by anthropic conditions in the surroundings, mainly phosphate and nitrate ions. Therefore, it can be concluded that shallow groundwaters in Flores neighborhood are unsuitable for human consumption, making it necessary for municipal public authorities to take action to solve the problem of water shortage in the borough, thus preventing the population from use those shallow groundwaters, as their consumption can bring health problems. However impurities tables Benevides region Pará Brazil physicalchemical physical chemical pH, , (pH) EC (EC) TDS, (TDS) color turbidity TH, TH (TH) elements waterquality processes Nevertheless surroundings Therefore borough problems (pH (EC (TDS (TH

ABSTRACT The physiological quality of soya bean seeds is a determining factor in establishing the crop in the field. The aim of the present study was to evaluate the physiological quality of soya bean seeds produced by plants grown from seeds of different sizes in two crop seasons. The BS 2606 SOYTECH, NS 6700 IPRO, NA 5909 RR, BS IRGA 1642 IPRO and LANÇA 58i60 IPRO cultivars were used, sown in 2019/2020 and 2020/2021. The experimental design was of randomised blocks, with treatments comprising seeds from plants grown from seeds of three sieve sizes (5.5, 6.0 and 6.5 mm for cultivars BS2606, NS 6700 IPRO, NA 5909 RR, LANÇA; and 6.0, 6.5 and 7.0 mm for the BS IRGA 1642 IPRO cultivar). The following tests were conducted: germination, first germination count, shoot and root length, total seedling dry weight, seedling emergence, accelerated ageing and electrical conductivity. The results were subjected to analysis of variance, and the mean values were compared using Tukey’s test at 5% probability. The size classification of the soya bean seeds has no effect on the germination of the seeds that are produced. Higher seed vigour in the NA 5909 RR cultivar, determined by the seedling emergence test, and accelerated ageing in NS 6700 IPRO, were obtained from seeds produced by plants grown from seeds classified as a sieve size of 6.5 mm. For the other cultivars, the size classification of the seeds had no effect on the vigour of the produced seeds. field seasons 260 SOYTECH 670 590 164 i 58i6 used 20192020 2019 2020 2019/202 20202021 2021 2020/2021 blocks 5.5, 55 5 (5.5 60 6 0 6. 65 BS2606 70 7 7. cultivar. cultivar . cultivar) conducted count length weight conductivity variance Tukeys Tukey s probability 26 67 59 16 58i 2019202 201 202 2019/20 2020202 2020/202 5.5 (5. BS260 2 1 201920 20 2019/2 202020 2020/20 5. (5 BS26 20192 2019/ 20202 2020/2 ( BS2 2020/

RESUMO: O melão de polpa alaranjada honeydew apresenta elevado potencial nutricional e econômico, sendo amplamente apreciado como fruta doce e refrescante. Portanto, avaliar amostras comerciais de produtos tão relevantes para o mercado de frutas frescas é de grande importância. O objetivo deste estudo foi investigar a capacidade antioxidante, os parâmetros de qualidade e a composição química de melões do mercado brasileiro. Os valores de pH e ºBrix determinados para as amostras de melão foram 6,5 ± 0,30 e 9,2 ± 0,80 g/100 g (peso fresco), respectivamente, o que está de acordo com os resultados esperados para melões de alta qualidade. A análise cromatográfica revelou a sacarose (49% do açúcar total) como principal açúcar, seguida pela frutose (30%) e glicose (21%). Os carotenóides, que estão diretamente ligados à cor laranja característica, apresentaram teor total de 270,59 µg/g (peso seco). Além disso, o maior valor de b* comparado ao valor de a* indica a maior contribuição da cor amarela. Quanto ao potencial antioxidante, além de apresentar capacidade antioxidante para ambos os métodos aplicados, DPPH e FRAP, níveis variando de 16,40 ± 0,21 µmol equivalente de ácido ascórbico/g a 56,98 ± 0,80 µmol equivalente de Trolox/g (peso seco) foram encontrados nos extratos de melão. Ademais, os resultados foram maiores em termos de FRAP do que em DPPH. Desta forma, os resultados destacam os melões avaliados como fontes valiosas de compostos bioativos, como carotenóides e fenólicos, que contribuem para suas propriedades antioxidantes. Além disso, análises de cor, pH e teor de sólidos solúveis totais também refletem os atributos de qualidade. RESUMO econômico refrescante Portanto importância brasileiro 65 6 5 6, 030 0 30 0,3 92 9 2 9, 080 80 0,8 g100 100 g/10 peso fresco, fresco , fresco) respectivamente 49% 49 (49 30% (30% 21%. 21 21% . (21%) característica 27059 270 59 270,5 µgg µg seco. seco disso b amarela aplicados 1640 16 40 16,4 021 0,2 ascórbicog ascórbico 5698 56 98 56,9 Troloxg Trolox Ademais forma bioativos fenólicos antioxidantes 03 3 0, 08 8 g10 10 g/1 4 (4 (30 (21% 2705 27 270, 164 1 16, 02 569 56, g1 g/ ( (3 (21 (2

ABSTRACT: Orange-fleshed non-netted honeydew melon has high nutritional and economic potential, being widely appreciated as a refreshing sweet fruit. Therefore, evaluating commercial samples of such relevant products for the fresh fruit market is of great importance. This study investigated the antioxidant capacity, quality parameters, and chemical composition of honeydew melons from the Brazilian market. The values of pH and °Brix determined for melon samples were 6.5 ± 0.30 and 9.2 ± 0.80 g/100 g (fresh weight), respectively, which agree with the results expected for high-quality melons. The chromatography analysis revealed sucrose (49% of total sugar) as the main sugar, followed by fructose (30%) and glucose (21%). Carotenoids, which are directly linked to the characteristic orange color, showed a total level of 270.59 µg/g (dry weight). Additionally, the higher b* value compared to a* value indicates the highest yellow contribution. Regarding the antioxidant assays, in addition to presenting antioxidant capacity for both methods applied, DPPH and FRAP, levels ranging from 16.40 ± 0.21 µmol ascorbic acid equivalent/g to 56.98 ± 0.80 µmol Trolox equivalent/g (dry weight) were reported in melon extracts. Moreover, the results were higher in terms of FRAP than DPPH. Therefore, the results underscore the evaluated honeydew melons as valuable sources of bioactive compounds, such as carotenoids and phenolics, which contribute to their antioxidant properties. Besides, analyses of color, pH, and total soluble solids content also reflect the quality attributes. ABSTRACT Orangefleshed Orange fleshed nonnetted non netted potential Therefore importance parameters Brix 65 6 5 6. 030 0 30 0.3 92 9 2 9. 080 80 0.8 g100 100 g/10 weight, weight , respectively highquality 49% 49 (49 sugar 30% (30% 21%. 21 21% . (21%) Carotenoids color 27059 270 59 270.5 µgg µg dry weight. Additionally b contribution assays applied 1640 16 40 16.4 021 0.2 equivalentg equivalent 5698 56 98 56.9 extracts Moreover compounds phenolics properties Besides attributes 03 3 0. 08 8 g10 10 g/1 4 (4 (30 (21% 2705 27 270. 164 1 16. 02 569 56. g1 g/ ( (3 (21 (2

RESUMO: Este estudo teve como objetivo avaliar o impacto da silagem de ração total de Megathyrsus maximus colhido com 70 cm de altura e concentrado no momento da silagem ou ração total de capim cortado a 70 cm, composta por Megathyrsus maximus colhido com 70 cm de altura (nos Exp. I e III) e silagem de ração total cortada a 130 cm, composta por Megathyrsus maximus colhido com 130 cm de altura e concentrado no momento da silagem ou ração total de Megathyrsus maximus colhido a 130 cm de altura (nos Exp. II e IV), sobre o metabolismo ruminal, a digestibilidade dos nutrientes, e o desempenho e as características de carcaça de cordeiros confinados. Os resultados mostraram que TMRS70 aumentou o pH ruminal no Exp. I, e TMRS130 exibiu maior digestibilidade do extrato etéreo, concentração de propionato e menor razão acético/propionato e pH ruminal em comparação com TMR130 no Exp. II. Nos Exp. III e IV, não houve efeito significativo sobre o desempenho e a qualidade da carcaça. No entanto, no Exp. IV, TMRS130 levou a uma diminuição no consumo de matéria seca e no ganho médio diário, enquanto cordeiros alimentados com TMR130 mostraram uma maior área de olho de lombo. A ensilagem da ração total poderia ser usada como um método de conservação para gramíneas jovens (70 cm) sem prejudicar o desempenho, metabolismo, carcaças e qualidade da carne. No entanto, recomenda-se mais estudos avaliando a análise econômica da alimentação com ensilagem de ração total (70 cm) em vez de ração totalmente misturada como método de conservação de forragem. RESUMO 7 nos Exp 13 IV , IV) nutrientes confinados TMRS TMRS7 TMRS13 etéreo acéticopropionato acético TMR TMR13 entanto diário lombo (7 carne recomendase recomenda se forragem 1 TMRS1 TMR1 (

ABSTRACT: This study assessed the impact of total mixed ration silage of Megathyrsus maximus harvested with 70 cm composed of Megathyrsus maximus harvested at 70 cm in height and concentrate at the time of silage or total mixed ration of grass cut at 70 cm composed of Megathyrsus maximus harvested with 70 cm in height (in Exp. I and III) and total mixed ration silage cut at 130 cm composed of Megathyrsus maximus harvested 130 cm height and concentrate at the time of silage or total mixed ration of Megathyrsus maximus harvested with 130 cm composed of Megathyrsus maximus harvested at 130 cm height (in Exp. II and IV), on rumen metabolism, nutrient digestibility, and the performance and carcass characteristics of feedlot lambs. The results showed that TMRS70 increased ruminal pH in Exp. I and TMRS130 exhibited higher ether extract digestibility, propionic concentration, and lower acetic to propionic ratio and ruminal pH compared to TMR130 in Exp. II. In Exp. III and IV, there was no significant effect on the performance and quality of the carcass. However, in Exp. IV, TMRS130 led to decreased dry matter intake and average daily gain, while lambs fed with TMR130 showed a higher rib-eye area. Total ration ensilage could be used as a conservation method for young grasses (70 cm) without impairing performance, metabolism, carcasses, and meat quality. However, further research is recommended to evaluate the economic analysis of feeding total ration ensilage (70 cm) instead of total mixed ration as a forage conservation method. ABSTRACT 7 Exp 13 IV , IV) metabolism digestibility TMRS TMRS7 TMRS13 concentration TMR TMR13 However gain ribeye rib eye area (7 carcasses 1 TMRS1 TMR1 (

ABSTRACT Beans are a vital component of the human diet, being able to supply a large part of the daily protein requirements of individuals, in addition to containing considerable amounts of iron, calcium, vitamins, carbohydrates, fiber, and lysine. Controlled germination is an accessible and effective technique that aims to improve the nutritional, functional, and sensory qualities of seeds intended for food consumption. This study aimed to characterize fresh and germinated beans of Phaseolus vulgaris (carioca, branco, preto, gordo varieties) and Vigna unguiculata (cowpea). The germination process was conducted in trays containing the sand substrate (350 g) in the environmental conditions of the laboratory. The fresh and germinated beans were evaluated for physicochemical variables in triplicate. The germination process increased moisture content, water activity, ash, pH, soluble alcohol acidity, proteins, ascorbic acid, phenols, tannins, flavonoids, anthocyanins, and carotenoids. On the other hand, there was a reduction in the content of lipids, starch, and total sugars in bean seeds. With the increase in bioactive compounds, it was found that the germination process is an excellent method for increasing the nutritional quality of beans. diet individuals iron calcium vitamins carbohydrates fiber lysine functional consumption carioca, carioca (carioca branco preto varieties cowpea. cowpea . (cowpea) 350 (35 g laboratory triplicate activity ash pH acidity proteins acid phenols tannins flavonoids anthocyanins carotenoids hand lipids starch compounds (cowpea 35 (3 3 (

RESUMO O feijão é um importante componente da dieta humana, sendo capaz de suprir grande parte das necessidades proteicas diárias dos indivíduos, além de conter quantidades consideráveis de ferro, cálcio, vitaminas, carboidratos, fibras e lisina. A germinação controlada é uma técnica acessível e eficaz que visa melhorar as qualidades nutricionais, funcionais e sensoriais de sementes destinadas ao consumo alimentar. O objetivo deste estudo foi caracterizar feijão Phaseolus vulgaris das variedades carioca, branco, preto, gordo e feijão-caupi (Vigna unguiculata) in natura e germinado. O processo de germinação foi realizado em bandejas contendo substrato areia (350 g), em condições ambientais de laboratório. Em seguida, os grãos in natura e germinados foram avaliados quanto às variáveis físico-químicas em triplicata. A germinação do feijão aumentou o teor de umidade, atividade de água, cinzas, pH, acidez álcool solúvel, proteínas, ácido ascórbico, fenóis, taninos, flavonóides, antocianinas e carotenóides. Por outro lado, houve redução no teor de lipídios, amido e açúcares totais nas sementes de feijão. Com o aumento dos compostos bioativos, constatou-se que o processo de germinação é um excelente método para aumentar a qualidade nutricional do feijão. humana indivíduos ferro cálcio vitaminas carboidratos lisina nutricionais alimentar carioca branco preto feijãocaupi caupi Vigna unguiculata germinado 350 (35 g, g , g) laboratório seguida físicoquímicas físico químicas triplicata umidade água cinzas pH solúvel proteínas ascórbico fenóis taninos flavonóides carotenóides lado lipídios bioativos constatouse constatou se 35 (3 3 (

Resumen Marco contextual: Las ambulancias de soporte vital inmediato (SVI) permiten al personal de enfermería intervenir en un contexto prehospitalario, con el apoyo de sus conocimientos técnico-científicos y de complejos protocolos de actuación y regulación médica a través de la telemedicina. Objetivo: Analizar las aportaciones de la intervención del personal de enfermería del SVI en la evolución del estado clínico de la persona en situación crítica (PSC). Metodología: Estudio cuantitativo, descriptivo-correlacional, retrospectivo, realizado en centros de SVI del norte de Portugal. Se analizaron 574 historias clínicas electrónicas entre el 1 de noviembre y el 31 de diciembre de 2019, correspondientes al mismo número de personas evaluadas. Se utilizó la escala National Early Warning Score (NEWS) para evaluar la evolución clínica de la PSC. Resultados: Se observó una evolución positiva en el score NEWS de la PSC, tras la intervención del personal de enfermería del SVI (M = 4,43 ± 3,901 vs 3,34 ± 3,329; sig < 0,001). Por el contrario, el riesgo clínico disminuyó significativamente tras la intervención del personal de enfermería. Conclusión: Se demostró la relevancia de la intervención del personal de enfermería del SVI en el contexto prehospitalario, como garantía de seguridad, calidad y mejora continua en la atención a la PSC.

Resumo Enquadramento: As ambulâncias de suporte imediato de vida (SIV) possibilitam ao enfermeiro capacidade de intervenção em contexto pré-hospitalar, suportada pelo seu conhecimento técnico-científico, protocolos complexos de atuação e regulação médica por telemedicina. Objetivo: Analisar os contributos da intervenção dos enfermeiros SIV, na evolução do estado clínico da pessoa em situação crítica (PSC). Metodologia: Estudo quantitativo, descritivo-correlacional, retrospetivo, realizado em meios SIV, na região norte de Portugal. Analisados 574 registos clínicos eletrónicos, entre 01 de novembro e 31 de dezembro de 2019, que correspondem ao mesmo número de pessoas avaliadas. Utilizada a escala National Early Warning Score (NEWS) para avaliar a evolução clínica da PSC. Resultados: Observou-se uma evolução positiva do score NEWS da PSC, após a intervenção do enfermeiro SIV (M = 4,43 ± 3,901 vs 3,34 ± 3,329; sig < 0,001). Em sentido inverso, o risco clínico diminuiu significativamente após a intervenção do enfermeiro. Conclusão: Demonstrou-se a relevância da intervenção do enfermeiro SIV no contexto pré-hospitalar, enquanto garantia de segurança, qualidade e melhoria contínua dos cuidados à PSC.

Abstract Background: Immediate life support (ILS) ambulances allow nurses to intervene in pre-hospital settings, supported by their technical-scientific knowledge and complex protocols of action and regulation through telemedicine. Objective: To analyze the contributions of nursing interventions in the evolution of the clinical state of critical patients. Methodology: Quantitative, descriptive-correlational, retrospective, and observational study conducted in ILS settings in northern Portugal. A total of 574 electronic clinical records were analyzed between 1 November and 31 December 2019, corresponding to the same number of people evaluated. The National Early Warning Score (NEWS) was used to assess the clinical evolution of critical patients. Results: There was a positive evolution of the NEWS score of critical patients after the intervention of ILS nurses (M = 4.43 ± 3.901 vs. 3.34 ± 3.329; sig < 0.001). Similarly, the clinical risk of critical patients decreased after the nurse’s intervention. Conclusion: This study demonstrated the importance of nurses in prehospital care, as a guarantee of safety, quality, and continuous improvement of care for critical patients.

Resumen: Introducción: Las hospitalizaciones por Ambulatory Care Sensitive Conditions es un indicador que mide la utilización de los servicios hospitalarios por problemas de salud que podrían haber sido prevenidos en el primer nivel de atención. El concepto se refiere a los procesos en que la atención ambulatoria efectiva puede ayudar a disminuir los riesgos de hospitalización, en un segundo nivel de atención. El objetivo del estudio fue construir y validar una lista uruguaya de problemas de salud sensibles a cuidados ambulatorios (PSSCA) según CIE-10. Metodología: Para la construcción de la lista inicial de códigos de PSSCA se realizó una revisión de los listados existentes y se propuso un listado inicial que fue validado a través del Método Delphi. Se propone un listado de 99 códigos diagnósticos de PSSCA adaptado a nuestro entono sanitario. Los mismos permiten identificar y cuantificar problemas de salud que pueden producir hospitalizaciones potenciamente evitables mediante cuidados ambulatorios accesibes y oportunos en el primer nivel de atención. Resultados: Se conformó un panel de 12 expertos. A partir de los datos obtenidos, considerando los 99 diagnósticos clasificados por CIE-10, éstos se pueden subclasificar en función de si la patología es infecciosa o no, obteniendo un resultado general de 62 patologías en un total de 99 que pueden ser clasificadas como infecciosas, lo que se corresponde a un 62 %. Discusión: De la comparación de la lista uruguaya de PSSCA a la que hemos arribado y las listas validadas utilizadas para la construcción inicial del listado de patologías propuesto, podemos decir que la primera presenta un mayor porcentaje de coincidencia con la lista de patologías de Bello Horizonte. Podemos mencionar que la mayoría de los problemas de salud identificados con base en el listado de PSSCA, son sensibles de ser resueltos con la atención primaria oportuna y de calidad que podría evitar o disminuir de una manera significativa su hospitalización. Conclusiones: Este trabajo describe el proceso de construcción y validación de una lista de códigos de PSSCA adaptados al contexto uruguayo a través del método Delphi. Hemos arribado a un listado que comprende un total de 99 diagnósticos, agrupadas en un total de diecinueve categorías que considera la especificidad del contexto uruguayo del indicador.

Abstract: Introduction: Hospitalizations for Ambulatory Care Sensitive Conditions is an indicator that measures the use of hospital services for health problems that could have been prevented at the first level of care. The concept refers to the processes in which effective outpatient care can help reduce the risks of hospitalization, at a second level of care. The objective of the study was to build and validate a Uruguayan list of health problems sensitive to outpatient care (PSS-CA) according to ICD-10. Methodology: To construct the initial list of PSSCA codes, a review of the existing lists was carried out and an initial list was proposed that was validated through the Delphi Method. A list of 99 PSSCA diagnostic codes adapted to our healthcare environment is proposed. They make it possible to identify and quantify health problems that can lead to potentially avoidable hospitalizations through accessible and timely outpatient care at the first level of care. Results: A panel of 12 experts was formed. From the data obtained, considering the 99 diagnoses classified by ICD-10, these can be subclassified depending on whether the pathology is infectious or not, obtaining a general result of 62 pathologies in a total of 99 that can be classified as infectious, which corresponds to 62%. Discussion: From the comparison of the Uruguayan list of PSSCA that we have arrived at and the validated lists used for the initial construction of the proposed list of pathologies, we can say that the first presents a higher percentage of coincidence with the list of pathologies of Bello Horizonte . We can mention that most of the health problems identified based on the PSSCA list are sensitive to being resolved with timely and quality primary care that could prevent or significantly reduce hospitalization. Conclusions: This work describes the process of construction and validation of a list of PSSCA codes adapted to the Uruguayan context through the Delphi method. We have arrived at a list that includes a total of 99 diagnoses, grouped into a total of nineteen categories that consider the specificity of the Uruguayan context of the indicator.

Resumo: Introdução: As Internações por Condições Sensíveis à Atenção Ambulatorial são um indicador que mede a utilização de serviços hospitalares para problemas de saúde que poderiam ter sido evitados no primeiro nível de atenção. O conceito refere-se aos processos em que um atendimento ambulatorial eficaz pode auxiliar na redução dos riscos de internação, em um segundo nível de atenção. O objetivo do estudo foi construir e validar uma lista uruguaia de problemas de saúde sensíveis à atenção ambulatorial (PSS-CA) segundo a CID-10. Metodologia: Para construir a lista inicial de códigos PSSCA foi realizada uma revisão das listas existentes e foi proposta uma lista inicial que foi validada através do Método Delphi. É proposta uma lista de 99 códigos de diagnóstico PSSCA adaptados ao nosso ambiente de saúde. Permitem identificar e quantificar problemas de saúde que podem levar a hospitalizações potencialmente evitáveis através de cuidados ambulatórios acessíveis e oportunos no primeiro nível de cuidados. Resultados: Foi formado um painel de 12 especialistas. A partir dos dados obtidos, considerando os 99 diagnósticos classificados pela CID-10, estes podem ser subclassificados consoante a patologia seja infecciosa ou não, obtendo-se um resultado geral de 62 patologias num total de 99 que podem ser classificadas como infecciosas, o que corresponde para 62%. Discussão: A partir da comparação da lista uruguaia de PSSCA a que chegamos e das listas validadas utilizadas para a construção inicial da lista de patologias proposta, podemos dizer que a primeira apresenta um maior percentual de coincidência com a lista de patologias de Belo Horizonte. Podemos mencionar que a maioria dos problemas de saúde identificados com base na lista PSSCA são sensíveis para serem resolvidos com cuidados primários oportunos e de qualidade que possam prevenir ou reduzir significativamente a hospitalização. Conclusões: Este trabalho descreve o processo de construção e validação de uma lista de códigos PSSCA adaptados ao contexto uruguaio através do método Delphi. Chegamos a uma lista que inclui um total de 99 diagnósticos, agrupados em um total de dezenove categorias que consideram a especificidade do contexto uruguaio do indicador.

Abstract Introduction: Vascular and neuropathic complications of diabetes cause diabetic foot, being the main risk factor for non-traumatic amputations. Objective: To analyze the available scientific evidence on lifestyle and self-care of patients at risk of diabetic foot. Methodology: Literature review using the preferred reporting items for systematic reviews and meta-analyses methodology; published in EBSCO host, Google academic, PubMed, Scielo and Elsevier; in English and Spanish from 2016 to 2022. Nursing articles were included, mentioning two or more variables of interest: diabetes mellitus, lifestyle, diabetic foot, and self-care; duplicates, no access, and gray literature were eliminated. From a total of 1,080 articles, 14 were included that met the inclusion criteria. Checklists were used to assess the quality of the manuscripts used. Results: Systematic reviews, observational, experimental and qualitative studies showed evidence that self-care can be influenced by culture, context and knowledge deficit, being this a risk factor for the development of diabetic foot. An association was found between the risk of diabetic foot with years of diagnosis, inadequate self-care of the feet and advanced age. Conclusion: The association between the self-care deficit and the risk of diabetic foot in the elderly was evidenced. It is recommended to broaden the search and include people under 40 years of age in order to establish effective preventive measures and reduce the risk of diabetic foot.

Abstrato Introdução: As complicações vasculares e neuropáticas da diabetes causam o pé diabético, sendo o principal fator de risco para amputações não traumáticas. Objetivo: Analisar a evidência científica disponível sobre o estilo de vida e o autocuidado dos doentes em risco de pé diabético. Metodologia: Revisão da literatura utilizando a metodologia preferred reporting items for systematic reviews and meta-analyses; publicada no EBSCO host, Google Scholar, PubMed, Scielo e Elsevier; em inglês e espanhol de 2016 a 2022. Foram incluídos artigos de enfermagem que mencionavam duas ou mais variáveis de interesse: diabetes mellitus, estilo de vida, pé diabético e autocuidado; foram removidos os duplicados, sem acesso e literatura cinzenta. De um total de 1.080 artigos, 14 que preencheram os critérios de inclusão foram incluídos. Foram utilizadas listas de verificação para avaliar a qualidade dos manuscritos utilizados. Resultados: Revisões sistemáticas, estudos observacionais, experimentais e qualitativos mostraram evidências de que o autocuidado pode ser influenciado pela cultura, contexto e défices de conhecimento, que são factores de risco para o desenvolvimento da doença do pé diabético. Foram encontradas associações entre o risco de pé diabético e os anos de diagnóstico, o autocuidado inadequado dos pés e a idade avançada. Conclusão: Verificou-se a associação entre défices de autocuidado e o risco de doença do pé diabético em idosos. Recomendamos o alargamento da pesquisa a pessoas com menos de 40 anos de idade, de forma a estabelecer medidas preventivas eficazes e reduzir o risco de doença do pé diabético.

Resumen Introducción: Las complicaciones vasculares y neuropáticas de la diabetes causan el pie diabético, siendo el principal factor de riesgo para amputaciones no traumáticas. Objetivo: Analizar la evidencia científica disponible sobre el estilo de vida y autocuidado de los pacientes con riesgo de pie diabético. Metodología: Revisión de la literatura mediante la metodología preferred reporting items for systematic reviews and meta-analyses; publicada en EBSCO host, Google académico, PubMed, Scielo y Elsevier; en inglés y español desde 2016 a 2022. Se incluyeron artículos de enfermería, que mencionaran dos o más variables de interés: diabetes mellitus, estilo de vida, pie diabético y autocuidado; se eliminaron duplicados, sin acceso abierto y literatura gris. De un total de 1,080 artículos se incluyeron 14 que reunieron los criterios de inclusión. Se emplearon listas de verificación para evaluar la calidad de los manuscritos utilizados. Resultados: Las revisiones sistemáticas, estudios observacionales, experimentales y cualitativos mostraron evidencias de que el autocuidado puede verse influenciado por la cultura, contexto y déficit de conocimientos, siendo este factor de riesgo para el desarrollo de pie diabético. Se encontró asociación entre el riesgo de pie diabético con años de diagnóstico, autocuidado inadecuado de los pies y edad avanzada. Conclusión: Se evidenció asociación entre déficit de autocuidado y riesgo de pie diabético en el adulto mayor. Se recomienda ampliar la búsqueda e incluir personas menores de 40 años para establecer medidas preventivas eficaces y reducir el riesgo de pie diabético.

Abstract Introduction. Weeds are one of the main problems in agricultural productivity due to their interactions with crops, such as alelopatic effects on germination. Objective. To evaluate the allelopathy of kikuyo grass (Cenchrus clandestinus) on the germination of beans (Phaseolus vulgaris L.) variety ICA Cerinza. Materials and methods. The study was conducted at the Quality Control Laboratory of the Universidad de Pamplona, Central Campus, Pamplona, Norte de Santander, Colombia, from May to August 2022. To each experimental unit (Petri dishe) with 12 been seeds, 6 mL of kikuyo aqueous extract (leaf, stem, and root) at three concentrations (1, 2.5, and 5 %), plus a control (0 %), were added, totaling 12 treatments. From day 0 to 12, the number of germinated seeds (NGS) was recorded, and the germination rate index (GRI) and germination index (IG) were calculated. The biomolecular profile of the aqueous extract was determined using the Fourier-transform spectroscopy. A completely randomized experimental design with a factorial arrangement (3x4), with repeated measures in each experimental unit, was employed. The intersuject factors were the organ type and concentration, while the intrasubject factor was the evaluation time (12 days). Results. Significant differences (p<0.001) were observed for NSG among treatments due to the concentration of the aqueous extract, as well as for IG, while GRI depended on the organ (p<0.05) and concentration (p<0.001), both negatively affected as the concentration increased. The infrared spectrum of the extract determined the presence of polyphenols, nitriles, and siloxanes. Conclusión. C. clandestinus affected NGS, GRI, and GI of P. vulgaris, with an allelopathic effect of the leaf aqueous extract at higher concentrations. Polyphenols, nitriles, and siloxanes associated with allelopathic effects were identified in the aqueous extracts.

Resumen Introducción. Las arvenses son uno de los principales problemas en la productividad agrícola, debido a interacciones con el cultivo, como efectos alelopáticos sobre la germinación. Objetivo. Evaluar la alelopatía del pasto kikuyo (Cenchrus clandestinus) en la germinación de frijol (Phaseolus vulgaris L.) variedad ICA Cerinza. Materiales y métodos. El estudio se realizó en el laboratorio de Control de Calidad de la Universidad de Pamplona, Campus Central, Pamplona, Norte de Santander, Colombia, en mayo-agosto 2022. A cada unidad experimental (caja de Petri) con doce semillas de frijol se le agregó 6 mL de extracto acuoso de kikuyo (hoja, tallo y raíz) en tres concentraciones (1, 2,5 y 5 %), más un testigo (0 %), para un total de doce tratamientos. En el lapso de 0 a 12 días, se registró el número de semillas germinadas (NSG), se calculó el índice de tasa de germinación (ITG) y el índice de germinación (IG), y se determinó el perfil biomolecular del extracto acuoso mediante la técnica de espectroscopia transformada de Fourier. Se utilizó un diseño experimental completamente al azar con arreglo factorial (3x4), con medidas repetidas en cada unidad experimental. Los factores intersujetos fueron el tipo de órgano y concentración, y el factor intrasujeto fue el tiempo (12 días) de evaluación. Resultados. Se observaron diferencias significativas (p<0,001) para NSG entre tratamientos por efecto de la concentración del extracto acuoso al igual que para IG, mientras que ITG dependió del órgano (p<0,05) y la concentración (p<0,001); ambos fueron afectados de forma negativa conforme aumentó la concentración. En el espectro infrarrojo del extracto se determinaron polifenoles, nitrilos y siloxanos. Conclusión. C. clandestinus afectó NSG, el ITG e IG de P. vulgaris, con efecto alelopático del extracto acuoso de hoja en mayor concentración. En los extractos acuosos se determinaron polifenoles, nitrilos y siloxanos, asociados a efecto alelopático.

Abstract Introduction. In organic agriculture, green manures and biocontrols are used as methods for fertilization and pest control. However, their independent application of these inputs increases production costs. A pelletized formulation is proposed to allow simultaneous application of both inputs. Objective. To evaluate the effect of pelletized Mucuna pruriens (L.) DC. inoculated with Trichoderma harzianum Rifai on nutritional intake, agricultural yield, and regulation of Fusarium oxysporum f. sp. lycopersici in tomato (Solanum lycopersicum L.). Materials and methods. The experiment was carried out in 2022 in Tablón del Guarco, Cartago, Costa Rica, using a randomized complete block design with seven treatments and seven repetitions. Two formulations (A and B) of biopellet (M. pruriens + zeolite + T. harzianum) were applied at three dosages (15, 30, 50 g/plant). T. harzianum was added at a rate of 5 g/kg of biopellet. Applications of each treatment were conducted every 15 days for a total of eight applications. At the time of planting, F. oxysporum was inoculated (100 mL/plant with a concentration of 1 x 103 CFU). Results. The application of biopellet achieved a yield and weight of high-quality fruits similar to the commercial control. There were no significant differences among treatments for second and third-quality fruits. The technical efficiency in controlling F. oxysporum reached 97.6 % with biopellet. This amendment increased the levels of Carbon (C), Nitrogen (N), and organic matter in the soil and affected the nutritional content of the plant foliage in the first 60 days after sowing. Conclusions. The biopellet has the capacity to make chemical and organic contributions to the soil, which improves the nutrition of the tomato crop. It could be also a biocontrol alternative against F. oxysporum and compatible with T. harzianum.

Resumen Introducción. En agricultura orgánica, se utilizan abonos verdes y biocontroladores como métodos de fertilización y control de plagas. Sin embargo, la aplicación independiente de estos incrementa los costos de producción. Se propone una presentación peletizada que permita la aplicación conjunta de ambos insumos. Objetivo. Evaluar el efecto de Mucuna pruriens (L.) DC. peletizada e inoculada con Trichoderma harzianum Rifai en el aporte nutricional, el rendimiento agrícola y la regulación de Fusarium oxysporum f. sp. lycopersici en tomate (Solanum lycopersicum L.). Materiales y métodos. El experimento se ejecutó el año 2022 en Tablón del Guarco, Cartago, Costa Rica, bajo un diseño de bloques completos al azar con siete tratamientos y siete repeticiones. Se aplicaron dos formulaciones (A y B) de biopélet (M. pruriens + zeolita + T. harzianum) en tres dosificaciones (15, 30, 50 g/planta). La adición de T. harzianum se efectuó a razón de 5 g por cada kilo del biopélet. Se realizaron aplicaciones cada 15 días por tratamiento para un total de ocho aplicaciones. Se inoculó F. oxysporum (100 mL/planta con una concentración de 1 x 103 UFC) a la siembra. Resultados. La aplicación del biopélet mostró un rendimiento y peso de frutos de primera calidad similar al testigo comercial. En frutos de segunda y tercera calidad, no hubo diferencias significativas entre tratamientos. La eficiencia en el control de F. oxysporum alcanzó el 97,6 % con biopélet. Esta enmienda aumentó los niveles de Carbono, Nitrógeno y materia orgánica en el suelo e influenció el contenido nutricional en el follaje a los 60 días después de la siembra. Conclusiones. El biopélet tiene la capacidad de realizar aportes químicos y orgánicos al suelo, por lo cual mejora la nutrición del cultivo del tomate. Los resultados sugieren además que es una alternativa de biocontrol contra F. oxysporum y compatible con T. harzianum.