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Peripheral spondyloarthritis (SpA) includes psoriatic arthritis (PsA), inflammatory bowel disease (IBD)-associated arthritis, reactive arthritis and undifferentiated peripheral SpA. These South African guidelines offer information on diagnosis, assessment and therapy of peripheral SpA. Emphasis is placed on a multidisciplinary team, and a treat-to-target strategy with escalation of therapy if the target of minimal or very low disease activity is achieved. Screening for and treatment of comorbidities are paramount.

https://doi.org/10.7196/SAMJ.2024.v114i10.2669

Análisis comparativo entre regiones del mundo relacionado con el consumo de sustancias psicoactivas en las últimas tres décadas
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Restrepo Betancur, Luis Fernando

Psychologia. Avances de la Disciplina

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Jun 2024, Volumen 18 Nº 1 Paginas 61 - 71

Resumen: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen El consumo de sustancias psicoactivas (SPA) trae efectos de adicción que modifican el pensamiento, la mente y el espíritu del adicto, no solo está generando un riesgo latente que afecta la salud de las personas, también trae consecuencias negativas para la sociedad misma, como mayor inversión económica en salud, presencia de habitantes de calle, aumento de delincuencia, entre otros aspectos. El objetivo del presente estudio consistió en evaluar las estadísticas relacionadas con el consumo de sustancias psicoactivas a nivel mundial en las últimas tres décadas. Para el análisis de la información se utilizó la técnica multivariada de la varianza MANOVA con contraste canónica ortogonal, se empleó el paquete estadístico SAS University en el proceso de la información. Como resultado destacado, se encontró divergencia estadística entre regiones, donde Norteamérica ocupa el primer lugar seguido de Asia y Oceanía. El mayor número de muertes por trastornos relacionados por el consumo de SPA se da en personas menores a los 49 años. El acelerado incremento y abuso en el consumo de SPA está generando altos índices de morbilidad y mortalidad a nivel global. Es una prioridad actuar con urgencia desde todos los frentes, profesionales de la salud, líderes políticos y comunitarios, entes educativos y núcleo familiar, para controlar esta problemática y tratar de disminuir el consumo y abuso de SPA.

Abstract The consumption of psychoactive substances (PAS) has addictive effects that modify the addict's thinking, mind and spirit, and not only generates a latent risk that affects people's health, but also has negative consequences for society itself, such as greater economic investment in health, the presence of street dwellers, and an increase in crime, among other aspects. The objective of this study was to evaluate the statistics related to the consumption of psychoactive substances worldwide in the last three decades. For the analysis of the information, the multivariate technique of variance MANOVA with orthogonal canonical contrast was used, and the SAS University statistical package was used to process the information. As an outstanding result, statistical divergence was found between regions, with North America occupying the first place followed by Asia and Oceania. The highest number of deaths due to disorders related to PAS consumption occurs in people under 49 years of age. The accelerated increase and abuse of PAS is generating high rates of morbidity and mortality globally. It is a priority to act urgently from all fronts, health professionals, political and community leaders, educational entities and the family nucleus, to control this problem and try to reduce the consumption and abuse of PAS.

https://doi.org/10.21500/19002386.6552

Relación entre el consumo de sustancias psicoactivas, alcohol y cigarrillo en estudiantes de Enfermería. Un estudio de corte transversal
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Ruiz, Jenny Paola Garzón

; Cortés-Muñoz, Fabián

; Buenaño, Mónica Alexandra Ferrer

; Hernández, Anggie Lizeth García

; Cortés, John Jalber Lombana

; Mondragón, José Luis Quimbay

; Cabezas, Mateo Alejandro Gil

; Fresneda, Angie Paola Parada

; Arcila, Johan Stiven Buitrago

; Cruz, Luis Fernando Agudelo

; Granados, Laura Daniela Fonseca

; Barrera, Jennifer Tatiana Ruiz

Revista Colombiana de Psiquiatría

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Mar 2024, Volumen 53 Nº 1 Paginas 73 - 84

Resumen: Es En | Texto: Es En | PDF: Es | PDF: En

RESUMEN Introducción: El incremento del consumo de sustancias psicoactivas (SPA), alcohol y cigarrillo en población joven se ha convertido en un problema de salud pública. La identificación de los factores que aumentan o disminuyen el riesgo de la exposición a estas sustancias y la relación que puede haber entre ellas resulta fundamental para la planificación de estrategias con enfoque de riesgo, razón por la cual se planteó el presente estudio. El objetivo es establecer el perfil de consumo de SPA, alcohol y cigarrillo y los factores asociados con dicho consumo en estudiantes del programa de Enfermería de una institución de educación superior. Métodos: Estudio cuantitativo, observacional y analítico de tipo corte transversal. Resultados: Se incluyó a 310 estudiantes de los semestres I a IX de un programa de Enfermería de una institución privada de educación superior de Bogotá. La prevalencia de consumo de SPA en el último ario fue del 2,96% (IC95%, 1,36-5,54); la marihuana es la sustancia de mayor consumo (55,55%). Las prevalencias de consumo de alcohol y cigarrillo durante los últimos 12 meses se estimaron en el 86,64% (IC95%, 83,24-91,0) y el 12,16% (IC95%, 8,4315,88) respectivamente. Se encontró una asociación estadísticamente significativa entre los consumos: tomar alcohol se asoció con el consumo de cigarrillo (OR = 3,22; p = 0,006) y fumar se asoció con el consumo de SPA (OR = 15,4; p <0,001). Conclusiones: En esta población universitaria, el consumo de alcohol aumenta la posibilidad de consumo de cigarrillo, y este a su vez aumenta la posibilidad del consumo de SPA.

ABSTRACT Background: The increase in the use of psychoactive substances, alcohol and cigarettes in young people has become a public health problem. The identification of factors that increase or reduce the risk of exposure to these substances and the possible relationship between them is essential for planning strategies with a risk approach, hence the reason for this study. The objective was to establish the profile of use of psychoactive substances, alcohol and cigarettes and the factors associated with such use in nursing students of a higher education institution. Methods: Quantitative, observational, analytical cross-sectional study. Results: We included 310 students from 1st to 9th semester of a Nursing programme from a prívate higher education institution in Bogotá. The prevalence of psychoactive substance use in the last year was 2.96% (95%CI, 1.36-5.54), with marijuana being the substance most used (55.55%). The prevalence of alcohol and cigarette use during the last 12 months was estimated at 86.64% (95%CI, 83.24-91.0) and 12.16% (95%CI, 8.43-15.88) respectively. A statistically significant association was found between the use of these substances: alcohol use was associated with cigarette use (OR = 3.22; P = 0.006) and smoking was associated with psychoactive substance use (OR = 15.4; P < 0.001). Conclusions: Alcohol use increases the likelihood of smoking cigarettes, and this in turn increases the likelihood of psychoactive substance use, in this university population.

https://doi.org/10.1016/j.rcp.2021.11.003

Customer satisfaction in mountain hotels within UNESCO Global Geoparks: an empirical study based on sentiment analysis of online consumer reviews
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Carvalho, Frederico

; Ramos, Ricardo F.

; Fortes, Nuno

Tourism & Management Studies

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Mar 2024, Volumen 20 Nº 1 Paginas 35 - 47

Resumen: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract The synergy between the accommodations and the untouched beauty of UNESCO’s Global Geoparks ensures an unforgettable encounter, blending comfort with adventure and relaxation with exploration. Although hotels have been previously investigated, the asymmetric results across mountain hotel customer satisfaction in UNESCO’s Global Geoparks are yet to be studied. This study aims to understand the online discourse and the reasons that satisfy a mountain hotel customer in UNESCO Global Geoparks. 5.590 online reviews were collected from 20 four and five-star mountain hotels in the Estrela UNESCO Global Geopark. Data were analysed through sentiment analysis (SA), and statistical analysis was used to acknowledge which variables influence satisfaction. We undertook a qualitative approach to understand the reasons for the identified sentiment. Results suggest that the seasonality, nationality, and travel experience influence satisfaction, and pool/spa is identified as critical for mountain hotel customers’ satisfaction. The new knowledge expands the understanding of the mountain hotel experience and the customers’ satisfaction with this specific type of hotel.

Resumo A sinergia entre os alojamentos e a beleza dos Geoparques Mundiais da UNESCO assegura um encontro inesquecível, combinando conforto com aventura e relaxamento com atividades de exploração. Os resultados assimétricos da satisfação dos clientes de hotéis de montanha nos Geoparques Mundiais da UNESCO ainda não foram estudados. Este estudo visa compreender o discurso online e as razões que satisfazem um cliente de hotel de montanha nos Geoparques Mundiais da UNESCO. Foram recolhidas 5.590 avaliações online de 20 hotéis de montanha de quatro e cinco estrelas na região do Estrela Geoparque Mundial da UNESCO. Os dados foram analisados através da análise de sentimento (SA), e a análise estatística foi utilizada para identificar quais são as variáveis que influenciam a satisfação. Foi adotada ainda uma abordagem qualitativa para compreender as razões do sentimento identificado. Os resultados sugerem que a sazonalidade, a nacionalidade e a experiência de viagem influenciam a satisfação, e a piscina/spa é identificada como fundamental para a satisfação. dos clientes de hotéis de montanha. O novo conhecimento amplia a compreensão da experiência em hotéis de montanha e a satisfação dos clientes com este tipo específico de hotel.

https://doi.org/10.18089/tms.20240103

Ordenamiento territorial agropecuario en micro territorios. Caso del Río Limón, en el Alto Catatumbo (Colombia) territorios Limón Colombia (Colombia
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Santiago Jácome, Juan Carlos

; González Escobar, Carlos Humberto

; Granobles Torres, Juan Carlos

Revista de Economia e Sociologia Rural

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2024, Volumen 62 Nº 2 elocation e272232

Resumen: Pt Es | Texto: Pt Es | PDF: Pt | PDF: Es

Abstract Based on the concern about what territorial factors can be determinant in a process of Agricultural Territorial Planning (OTA) in the Limón River sub-basin, a micro-territory in Alto Catatumbo, in the northeast of Colombia, it was carried out, through the application of techniques of qualitative and quantitative evaluation, a review of the conditions of Rural Territorial Development (DTR), Territorial Governance (GT), performance of Agricultural Production Systems (SPA), Environmental conflicts and Territorial Tensions. The sub-basin is an area shared between three municipalities and two departments, it has a population of around five thousand inhabitants, mostly rural. Agricultural production is its main economic activity and the source of a strong conflict over land and water use. Composite indices of DTR, GT and SPA performance were prepared and applied, olso environmental reports and municipal planning documents were reviewed. The results indicate that the determining factors of the OTA in the sub-basin are related to low levels of social conditions and a weak Territorial Governance, confirm the high conflicts of land and water use and raise the need to objectively define the long-term vision of the territory. (OTA subbasin, subbasin sub basin, basin microterritory micro territory Catatumbo Colombia out evaluation DTR , (DTR) GT, (GT) SPA, (SPA) Tensions departments inhabitants rural applied reviewed longterm long term (DTR (GT (SPA

Resumen A partir de la inquietud sobre qué factores territoriales pueden ser determinantes en un proceso de Ordenamiento Territorial Agropecuario (OTA) en la subcuenca del Río Limón, un microterritorio en el Alto Catatumbo, al nororiente de Colombia, se realizó, mediante la aplicación de técnicas de evaluación cualitativas y cuantitativas, una revisión de las condiciones del Desarrollo Territorial Rural (DTR), la Gobernanza Territorial (GT), el desempeño de los Sistemas de Producción Agropecuario (SPA), los conflictos Medio Ambientales y las Tensiones Territoriales. La subcuenca es un área compartida entre tres municipios y dos departamentos, presenta una población de alrededor de cinco mil habitantes, en su mayoría rural. La producción agropecuaria es su principal actividad económica y la fuente de un fuerte conflicto de uso del suelo y el agua. Se elaboraron y aplicaron índices compuestos de DTR, GT y de desempeño de los SPA, se revisaron informes ambientales y documentos de planeación municipal. Los resultados indican que los factores determinantes del OTA en la subcuenca se relacionan con bajos niveles de condiciones sociales y una débil Gobernanza Territorial, confirman los conflictos altos de uso del suelo y el agua, y plantea la necesidad de definir objetivamente la visión de largo plazo del territorio. (OTA Limón Catatumbo Colombia realizó cuantitativas DTR , (DTR) GT, (GT) SPA (SPA) Territoriales departamentos habitantes rural agua municipal territorio (DTR (GT (SPA

https://doi.org/10.1590/1806-9479.2022.272232

The Social Participation on the Other Side of the Counter: Bureaucracy Perceptions in the Social Assistance* Counter Assistance
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Direito, Denise do Carmo

; Almeida, Debora Rezende de

Brazilian Political Science Review

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2024, Volumen 18 Nº 2 elocation e0006

Resumen: En | Texto: En | PDF: En

This paper proposes an analytical and empirical shift to identify the meanings that state actors mobilize regarding social participation. It innovates by focusing on the perceptions of bureaucrats about participatory institutions and by proposing the dialogue between two sets of literature: the approaches of Participatory Institutions (PI) and of the Sociology of Public Action (SPA). From the former, it takes up the debate on the meanings of participation, while from the latter it takes on an understanding of bureaucrats as actors who mediate between the state and society and of the role of interaction in defining state action. It carries out a case study in the middle-echelon bureaucracy of the National Secretariat for Social Assistance, covering the period of political-institutional changes after the presidential impeachment. The main technique is qualitative and content analysis of 44 semi-structured interviews with DAS 04 and 05 bureaucrats. It concludes that there are multiple meanings of social participation among bureaucrats, influenced by attributes such as professional and management links, subnational experiences in politics and PIs, and academic background. It identifies a gradual decrease in the relevance of non-state actors for decision-making and the redefinition of participation as listening, which becomes both formal and uninterested. literature PI (PI SPA. SPA . (SPA) former action middleechelon middle echelon Assistance politicalinstitutional political institutional impeachment 4 semistructured semi structured 0 links PIs background nonstate non decisionmaking decision making listening uninterested (SPA

https://doi.org/10.1590/1981-3821202400020006

Estabilidad dimensional de hidrocoloides irreversibles de vaciado convencional y de vaciado de tiempo extendido disponibles en el mercado uruguayo.
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García, Andrés

; Mederos, Matías

; León, Elisa de

; Tessore, Romina

; Vázquez, Priscila

; García, María de los Ángeles

; Suiffet, Germán

; Pérez, Santiago

; Goinheix, Rodrigo

; Cuevas-Suárez, Carlos

; Grazioli, Guillermo

Odontoestomatología

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2024, Volumen 26 Nº 43 elocation e232

Resumen: Es En Pt | Texto: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen Objetivo. Comparar la estabilidad dimensional de un hidrocoloide irreversible de vaciado convencional con hidrocoloides irreversibles de vaciado extendido. Metodología. Fueron evaluados cuatro productos con indicación de vaciado extendido: Jeltrate Plus (Denstply Sirona), Hydrogum 5 (Zhermack SpA), Algimax (Major), Kromopan (Lascod) y un producto de vaciado convencional (Tropicalgin; Zhermack SpA). Con cada producto se realizaron 10 impresiones y se vaciaron en yeso tipo III en cinco tiempos de almacenamiento diferentes (0, 24, 96, 120 y 168 horas). Un escáner para modelos tridimensionales se utilizó para digitalizar los modelos de yeso y realizar las mediciones correspondientes: sumatoria de las longitudes, variabilidad dimensional, porcentaje de variabilidad. Resultados. Las cinco marcas comerciales presentaron una sumatoria de longitudes mayor al grupo control (p<0,033). A las 0, 24 y 96h Tropicalgin e Hydrogum 5 presentaron significativamente menor variación dimensional en comparación con el modelo maestro (p<0,001). Los porcentajes de variabilidad oscilaron entre un 0.24 a 0.91%. Conclusiones. La estabilidad dimensional depende del producto utilizado. Almacenado correctamente, el hidrocoloide irreversible de vaciado convencional parece no sufrir alteraciones significativas hasta 96h, mientras que en el caso de Hydrogum 5 parece mantener su estabilidad dimensional hasta 168h.

Abstract Aim . Compare the dimensional stability of a conventional pouring irreversible hydrocolloid with extended pouring irreversible hydrocolloids. Methodology. Four products with extended emptying indication were evaluated: Jeltrate Plus (Denstply Sirona), Hydrogum 5 (Zhermack SpA), Algimax (Major), Kromopan (Lascod) and a conventional emptying product (Tropicalgin; Zhermack SpA). For each product, 10 impressions were made and cast in type III plaster at five different storage times (0, 24, 96, 120 and 168 hours). A three-dimensional model scanner was used to digitize the plaster models and make the corresponding measurements: sum of lengths, dimensional variability, percentage of variability. Results . The five commercial brands presented a greater sum of lengths than the control group (p<0,033). At 0, 24 and 96h Tropicalgin and Hydrogum 5 presented significantly less dimensional variation compared to the master model (p<0,001). The variability percentages ranged from 0.24 to 0.91%. Conclusions. Dimensional stability depends on the product used. Stored correctly, the conventionally cast irreversible hydrocolloid appears not to undergo significant alterations up to 96h, while in the case of Hydrogum 5 it appears to maintain its dimensional stability up to 168h.

Resumo. Objetivo. Comparar a estabilidade dimensional de um hidrocolóide irreversível de vazamento convencional com hidrocolóides irreversíveis de vazamento prolongado. Metodologia. Foram avaliados quatro produtos com indicação de vazamento estendido: Jeltrate Plus (Denstply Sirona), Hydrogum 5 (Zhermack SpA), Algimax (Major), Kromopan (Lascod) e um produto de vaziamento convencional (Tropicalgin; Zhermack SpA). Para cada produto foram feitas 10 impressões e vazadas em gesso tipo III em cinco tempos de armazenamento diferentes (0, 24, 96, 120 e 168 horas). Um scanner de modelos tridimensionais foi utilizado para digitalizar os modelos de gesso e fazer as medições correspondentes: soma dos comprimentos, variabilidade dimensional, percentagem de variabilidade. Resultados. As cinco marcas comerciais apresentaram somatório de comprimentos maior que o grupo controle (p<0,033). Nos tempos 0, 24 e 96h Tropicalgin e Hydrogum 5 apresentaram variação dimensional significativamente menor em comparação ao modelo Mestre (p<0,001). Os percentuais de variabilidade variaram de 0,24 a 0,91%. Conclusões. A estabilidade dimensional depende do produto utilizado. Armazenado corretamente, o hidrocolóide irreversível de vaziamento convencional convencionalmente parece não sofrer alterações significativas até 96h, enquanto no caso do Hydrogum 5 parece manter sua estabilidade dimensional até 168h.

https://doi.org/10.22592/ode2024n43e232

Prevalence of spondyloarthritis in inflammatory bowel disease according ASAS and ultrassonography and its correlation with plasma calprotectin
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Huber, Míriam Küster

; Valim, Valeria

; Serrano, Érica Vieira

; Mendonça, José Alexandre

; Lourenço, Rafael Burgomeister

; Santo, Thaisa Moraes Ribeiro Espírito

; Nordal, Hilde

; Bissoli, Maria de Fátima

; Gavi, Maria Bernadete Renoldi de Oliveira

Advances in Rheumatology

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2024, Volumen 64 elocation 27

Resumen: En | Texto: En | PDF: En

Abstract Background Enteropathic spondyloarthritis is underdiagnosed and inflammatory biomarkers and ultrasonography (US) could be useful for screening inflammatory bowel disease (IBD) patients. The objective of this study was to evaluate the prevalence of spondyloarthritis (SpA) in IBD patients, according to the Assessment of SpondyloArthritis International Society (ASAS) criteria and the correlation of results of US of entheses and joints with plasma calprotectin levels. Methods This was an observational cross-sectional study. Patients from the IBD outpatient clinic of a reference center were evaluated according to ASAS criteria classification, results of US of entheses and joints, and inflammatory biomarker measurements (erythrocyte sedimentation rates, C-reactive protein levels, fecal and plasma calprotectin levels). A p value lower than 0.05 was considered significant. Results A total of 30.5% of the studied sample (n = 118) of patients with IBD presented at least one inflammatory musculoskeletal manifestation. The overall prevalence of enteropathic SpA was 13.55%, with 10.16% axial SpA and 4.23% peripheral SpA according to the ASAS criteria. A total of 42.1% of patients had an MASEI score greater than 18, 35.2% had synovitis, and 14.7% had tenosynovitis on US, increasing the frequency of diagnosis of entero- pathic SpA to 22.8%. Plasma calprotectin levels were similar to those in healthy controls, and correlated only with the fecal calprotectin level (p 0.041). Conclusions A total of 13.5% of patients met the criteria in accordance with the ASAS criteria for enteropathic SpA, which increased to 22.8% with the addition of US. The prevalence of enthesitis, synovitis and tenosynovitis by US of symptomatic joints and entheses were 42%, 35% and 14.7% respectively. Plasma calprotectin was correlated with fecal calprotectin but not with inflammatory biomarkers or US or ASAS criteria. (US (IBD (SpA (ASAS crosssectional cross sectional classification erythrocyte rates Creactive C reactive . levels) 005 0 05 0.0 significant 305 30 5 30.5 n 118 manifestation 1355 13 55 13.55% 1016 10 16 10.16 423 4 23 4.23 421 42 1 42.1 18 352 35 2 35.2 147 14 7 14.7 entero 228 22 8 controls 0.041. 0041 0.041 041 0.041) 135 13.5 22.8 enthesitis 42% respectively 00 0. 3 30. 11 13.55 101 10.1 4.2 42. 35. 14. 004 0.04 04 13. 22. 10. 4.

https://doi.org/10.1186/s42358-023-00348-6

To be or not to B27 positive: implications for the phenotypes of axial spondyloarthritis outcomes. Data from a large multiracial cohort from the Brazilian Registry of Spondyloarthritis B B2 positive outcomes
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Resende, Gustavo Gomes

; Saad, Carla Goncalves Schahin

; Marques, Claudia Diniz Lopes

; Ribeiro, Sandra Lúcia Euzébio

; Gavi, Maria Bernadete Renoldi de Oliveira

; Yazbek, Michel Alexandre

; Marinho, Adriana de Oliveira

; Menin, Rita de Cássia

; Ochtrop, Manuella Lima Gomes

; Soares, Andressa Miozzo

; Cavalcanti, Nara Gualberto

; Carneiro, Jamille Nascimento

; Werner de Castro, Glaucio Ricardo

; Fernandes, José Mauro Carneiro

; Souza, Elziane da Cruz Ribeiro E

; Alvarenga, Corina Quental de Menezes

; Vieira, Rejane Maria Rodrigues de Abreu

; Machado, Natalia Pereira

; Ximenes, Antônio Carlos

; Gazzeta, Morgana Ohira

; Albuquerque, Cleandro Pires de

; Skare, Thelma Larocca

; Keiserman, Mauro Waldemar

; Kohem, Charles Lubianca

; Benacon, Gabriel Sarkis

; Rocha, Vítor Florêncio Santos

; Lage, Ricardo da Cruz

; Malheiro, Olivio Brito

; Golebiovski, Rywka Tenenbaum Medeiros

; Oliveira, Thauana Luiza

; Duque, Ruben Horst

; Londe, Ana Carolina

; Pinheiro, Marcelo de Medeiros

; Sampaio-Barros, Percival Degrava

Advances in Rheumatology

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2024, Volumen 64 elocation 33

Resumen: En | Texto: En | PDF: En

Abstract Background There is a remarkable variability in the frequency of HLA-B27 positivity in patients with spondyloarthritis (SpA), which may be associated with different clinical presentations worldwide. However, there is a lack of data considering ethnicity and sex on the evaluation of the main clinical and prognostic outcomes in mixed-race populations. The aim of this study was to evaluate the frequency of HLA-B27 and its correlation with disease parameters in a large population of patients from the Brazilian Registry of Spondyloarthritis (RBE). Methods The RBE is a multicenter, observational, prospective cohort that enrolled patients with SpA from 46 centers representing all five geographic regions of Brazil. The inclusion criteria were as follow: (1) diagnosis of axSpA by an expert rheumatologist; (2) age ≥18 years; (3) classification according to ASAS axial. The following data were collected via a standardized protocol: demographic data, disease parameters and treatment historical. Results A total of 1096 patients were included, with 73.4% HLA-B27 positivity and a mean age of 44.4 (±13.2) years. Positive HLA-B27 was significantly associated with male sex, earlier age at disease onset and diagnosis, uveitis, and family history of SpA. Conversely, negative HLA-B27 was associated with psoriasis, higher peripheral involvement and disease activity, worse quality of life and mobility. Conclusions Our data showed that HLA-B27 positivity was associated with a classic axSpA pattern quite similar to that of Caucasian axSpA patients around the world. Furthermore, its absence was associated with peripheral manifestations and worse outcomes, suggesting a relevant phenotypic difference in a highly miscegenated population. HLAB27 HLAB HLA B27 B HLA-B2 SpA, , (SpA) worldwide However mixedrace mixed race populations RBE. . (RBE) multicenter observational 4 Brazil follow 1 (1 rheumatologist 2 (2 18 ≥1 years 3 (3 axial protocol historical 109 included 734 73 73.4 444 44 44. ±13.2 132 13 (±13.2 uveitis Conversely psoriasis activity mobility world Furthermore HLAB2 B2 HLA-B (SpA (RBE ( ≥ 10 7 73. ±13. (±13. ±13 (±13 ±1 (±1 ± (±

https://doi.org/10.1186/s42358-024-00372-0

10.

Presentation of enthesitis-related arthritis and juvenile-onset spondyloarthritis: a cross-sectional study in a pediatric and adult clinic enthesitisrelated enthesitis related juvenileonset juvenile onset spondyloarthritis crosssectional cross sectional
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Lanças, Sean Hideo Shirata

; Furlan, Matheus Zanata Brufatto

; Fernandes, Taciana de Albuquerque Pedrosa

; Drumond, Sula Glaucia Lage

; Magalhães, Claudia Saad

Advances in Rheumatology

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2024, Volumen 64 elocation 39

Resumen: En | Texto: En | PDF: En

Abstract Background Juvenile idiopathic arthritis (JIA) comprises a whole spectrum of chronic arthritis starting before 16 years of age. The study aims to explore the clinical and demographic descriptors, treatment, and disease progression of enthesitis-related arthritis (ERA) in comparison with juvenile-onset spondyloarthritis (SpA). Methods Cross-sectional analysis of consecutive patients in two dedicated clinics, with a single visit and retrospective case-notes review. Arthritis, enthesitis and sacroiliitis were evaluated by scoring disease activity and damage. Continuous variables were reported by median, interquartile range; categorical variables were reported by the frequency comparison of the two groups. Results Thirty-three cases were included, being 23 (69.7%) with ERA. The median age at diagnosis was 12.5 y (SpA) vs. 9 y (ERA) (p < 0.01); the time from symptom onset to diagnosis was 5.5 y (SpA) vs. 1.5 y (ERA) (p < 0.03). In both groups, the predominant presentation was a single joint or < 5 lower limb joints and asymmetric involvement, with a high frequency of enthesitis. There was a higher frequency of mid-tarsal and ankle synovitis in the ERA group and hip involvement in those with SpA. The comparison of the frequency of spine symptoms at presentation, 30% SpA vs. 21.7% ERA (p = 0.7), was not significant, and radiographic progression to spinal involvement occurred in 43.5% of ERA patients. The median time for spinal progression and age at onset was 2.2 and 12 y for ERA, and 4 and 16.5 y for SpA, respectively. Activity and damage scores were not significantly different between the groups. Treatment comparison resulted in 91.3% of ERA and 100% SpA being treated, predominantly with NSAIDs in both groups, followed by DMARDs and biologics, with a higher frequency of biologics in SpA. Conclusion The main differences were the late diagnoses of SpA, and the hip and spine involvement, with higher frequency of biologic treatment in juvenile-onset SpA compared to ERA. JIA (JIA 1 descriptors enthesitisrelated related (ERA juvenileonset juvenile . Crosssectional Cross sectional clinics casenotes case notes review Arthritis range groups Thirtythree Thirty three included 2 69.7% 697 69 7 (69.7% 125 12. (SpA vs p 0.01 001 0 01 0.01) 55 5. 15 1. 0.03. 003 0.03 03 0.03) midtarsal mid tarsal 30 217 21 21.7 0.7, 07 0.7 , 0.7) significant 435 43 43.5 22 2. 165 16. respectively 913 91 3 91.3 100 treated 69.7 6 (69.7 0.0 00 21. 0. 43. 91. 10 69. (69. (69 (6 (

https://doi.org/10.1186/s42358-024-00378-8

11.

Composition, life-history, and population dynamics of the Chironomidae from a tropical high-altitude stream (Saltana River, Ecuador) Composition lifehistory, lifehistory life history, history life-history highaltitude high altitude Saltana River Ecuador
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Prat i Fornells, Narcís

; Encalada, Andrea C.

; Villamarín, Christian

; Ríos-Touma, Blanca

Acta Limnologica Brasiliensia

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2024, Volumen 36 elocation e40

Resumen: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo: Objetivo estudar a composição e a dinâmica populacional de Chironomidae (Diptera) de um riacho tropical de altitude no Equador. Métodos As amostras foram coletadas no rio Saltana entre abril de 2009 e novembro de 2010. Os parâmetros físico-químicos como fluxo, oxigênio dissolvido, condutividade, pH e temperatura foram medidos em cada campanha de amostragem. Larvas e pupas foram coletadas com um amostrador Hess em diferentes substratos. Já os adultos foram amostrados com armadilhas anfíbias de emergência por 24 horas durante cada campanha de amostragem. Todo o material coletado foi triado e identificado no laboratório. A biomassa foi calculada usando o peso individual das larvas de diferentes ínstares multiplicado pela densidade de cada ínstar em cada amostra. Resultados Um total de 18 táxons larvais foi encontrado em 14 gêneros diferentes nas amostras bentônicas. A subfamília Orthocladiinae apresentou a maior riqueza (12 gêneros), seguida por Podonominae, Diamesinae e Chironominae, com dois gêneros cada. Os táxons mais frequentes foram Cricotopus sp3, C. (Oliveiriella) rieradevallae e Genus 1 sp a. As densidades totais flutuaram muito de um mês para outro, seguindo as mudanças das espécies mais abundantes, e apenas uma espécie mostrou relação com os substratos. Os valores de biomassa são mais baixos de junho a agosto em ambos os anos, o que corresponde à estação de alto fluxo. Conclusões A temperatura fria do rio Saltana durante todo o ano (6-7 °C) e a variabilidade do fluxo determinam os baixos valores de riqueza e densidade. Não está claro se os indivíduos apresentaram ciclos de vida muito curtos ou longos devido à temperatura constante durante todo o ano. No entanto, há uma clara assincronia nos ciclos de vida devido à presença de adultos emergentes ao longo do ano. Resumo Diptera (Diptera Equador 200 2010 físicoquímicos físico químicos dissolvido condutividade amostragem substratos 2 laboratório amostra bentônicas 12 (1 gêneros, , gêneros) Podonominae Chironominae sp3 C Oliveiriella (Oliveiriella outro abundantes anos 67 6 7 (6- °C entanto 20 201 ( (6

Abstract: Aim To study the composition and population dynamics of Chironomidae (Diptera) from a high-altitude tropical stream in Ecuador. Methods Samples were taken at Saltana River between April 2009 and November 2010. Physico-chemical parameters, such as flow, dissolved oxygen, conductivity, pH, and temperature, were measured in each sampling campaign. Larvae and pupae sampling was conducted with a Hess sampler in different substrates. During each sampling campaign, adults were sampled using amphibious emergence traps for 24 hours. All materials collected were separated and classified in the laboratory. The biomass was calculated using the individual weight of the larvae of different instars multiplied by the density of each instar at each sample. Results A total of 18 larval taxa were found in 14 different genera in the benthic samples. The subfamily Orthocladiinae showed the highest richness (12 genera), followed by Podonominae, Diamesinae, and Chironominae, with two genera each. The most frequent taxa were Cricotopus sp.3, C. (Oliveiriella) rieradevallae, and Genus 1 sp.a. Total densities fluctuate very much from one month to another following the changes of the most abundant species, and only one species showed a relationship with the substrates. Biomass values are lower from June to August of both years, which matches the high flow season. Conclusions The Saltana River’s cold temperature (6-7 °C) and the flow variability determine the low richness, density and biomass throughout the year. It is unclear if individuals showed very short or long-life cycles due to constant temperature throughout the year. However, there is a clear asynchrony in life cycles due to the presence of emerging adults throughout the year. Abstract Diptera (Diptera highaltitude altitude Ecuador 200 2010 Physicochemical Physico chemical parameters oxygen conductivity pH campaign substrates 2 hours laboratory sample samples 12 (1 genera, , genera) Podonominae Diamesinae Chironominae sp3 sp 3 sp.3 C Oliveiriella (Oliveiriella rieradevallae spa sp.a years season Rivers s 67 6 7 (6- °C year longlife long However 20 201 ( sp. (6

https://doi.org/10.1590/s2179-975x11023

12.

Sacroiliac and spine imaging in spondyloarthritis: Does phenotype or sex matter? spondyloarthritis matter
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Pereira, Gabriel Caetano

; Machado, Natalia Pereira

; Gomes, André Francisco

; Assad, Rodrigo Luppino

; Carneiro, Fabio Henrique

; Azevedo, Valderílio Feijó

Advances in Rheumatology

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2024, Volumen 64 elocation 68

Resumen: En | Texto: En | PDF: En

Abstract Background Spondyloarthritis (SpA) encompasses a spectrum of immune-mediated inflammatory conditions primarily affecting the axial skeleton, including sacroiliitis and spondylitis, each with distinct features. This study aimed to investigate imaging disparities, focusing on sacroiliac magnetic resonance and spine radiography, across phenotypes and between males and females in axial SpA. Method A cross-sectional study was conducted to assess clinical data, laboratory findings, magnetic resonance imaging (MRI) scores of sacroiliac joints using the Spondyloarthritis Research Consortium of Canada (SPARCC) and Sacroiliac Joint Structural Score (SSS), and cervical and lumbar spine radiographs utilizing the Modified Stoke Ankylosing Spondylitis Spine Score (mSASSS). The study aimed to compare these parameters between two groups: axial spondyloarthritis (axSpA, radiographic and non-radiographic) and axial psoriatic arthritis (axPsA), as well as between males and females. Results Ninety-four patients were included, with 62 patients in the axSpA group and 32 patients in the axPsA group. There were no differences in disease activity, mobility, radiographic damage in the spine (Modified Stoke Ankylosing Spondylitis Spine Score– mSASSS), or sacroiliac magnetic resonance imaging (MRI) scores (Spondyloarthritis Research Consortium of Canada Magnetic Resonance Imaging Index - SPARCC and Sacroiliac Joint Structural Score - SSS) between the two phenotypes. Regarding sex, in imaging exams, men had higher mSASSS (p = 0.008), SSS (p = 0.001), and fat metaplasia (MG) score based on SSS (p = 0.001), while women had significantly higher SPARCC scores (p = 0.039). In the male group, the presence of HLA-B27 allele had an impact on more structural lesions on MRI (SSS), p = 0.013. Conclusion In this study, imaging of sacroiliac joints and spine in patients with axial SpA did not show differences in phenotypes but did reveal differences based on sex, which may have an impact on future diagnostic recommendations. Further studies are needed to confirm these findings. (SpA immunemediated immune mediated skeleton spondylitis features disparities radiography crosssectional cross sectional data findings (MRI (SPARCC SSS, , (SSS) mSASSS. . (mSASSS) groups axSpA, (axSpA nonradiographic non non-radiographic axPsA, (axPsA) Ninetyfour Ninety four included 6 3 activity mobility mSASSS, mSASSS) sex exams 0.008, 0008 0.008 0 008 0.008) 0.001, 0001 0.001 001 0.001) MG (MG 0.039. 0039 0.039 039 0.039) HLAB27 HLAB HLA B27 B HLA-B2 0013 013 0.013 recommendations (SSS (mSASSS (axPsA 000 0.00 00 003 0.03 03 HLAB2 B2 HLA-B 01 0.01 0.0 0.

https://doi.org/10.1186/s42358-024-00411-w

13.

Reporte de pacientes con espondiloartritis y arteritis de Takayasu en Argentina: ¿asociación causal o casual?
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Ceccato, Federico

; Schneeberger, Emilce E

; Scolnik, Marina

; Citera, Gustavo

; Castel del Cid, Cecilia

; Albiero, Juan Alejandro

Revista argentina de reumatología

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Dic 2023, Volumen 34 Nº 3 Paginas 73 - 80

Resumen: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Introduction: both spondyloarthritis (SpA) and Takayasu arteritis (TAK) are rare diseases, and their association is even rarer. Objectives: to present a series of patients with a concomitant diagnosis of SpA or with features of SpA and TAK in Argentina and review the literature regarding this association. Materials and methods: the demographic, clinical and therapeutic characteristics of patients with a concomitant diagnosis of SpA or with some features of SpA and TAK were collected from different health centers in Argentina. Results: 7 patients are described, of which 4 had SpA, one with juvenile axial involvement (axSpA), another with psoriatic arthritis (PsA), another with ankylosing spondylitis (AS) and the last patient with pure axSpA and 3 of them had features of SpA (Crohn's disease, psoriasis and asymmetric oligoarthritis of large joints). In most cases, SpA features presented a median of 4 years before TAK. Conclusions: several case reports and case series reported overlap between these two diseases. Although they could share a certain common genetic basis, we still do not have solid evidence that allows us to estimate that this association is not coincidental.

Resumen Introducción: tanto las espondiloartritis (EspA) como la arteritis de Takayasu (TAK) son enfermedades infrecuentes y su asociación es aún más rara. Objetivos: presentar una serie de pacientes con diagnóstico concomitante de EspA o con rasgos de EspA y TAK en Argentina, y realizar una revisión de la literatura respecto de esta asociación. Materiales y métodos: se recopilaron las características demográficas, clínicas y terapéuticas de pacientes con diagnóstico concomitante de EspA o con algunos rasgos de EspA y TAK, de distintos centros de salud de la República Argentina. Resultados: se describen 7 pacientes, de los cuales 4 presentaban EspA, uno con compromiso axial (EspAax) juvenil, otro con artritis psoriásica (APs), otro con espondilitis anquilosante (EA) y el último con EspAax pura, y 3 de ellos tuvieron rasgos de EspA (enfermedad Crohn, psoriasis y oligoartritis asimétrica de grandes articulaciones). En la mayoría de los casos, los rasgos de EspA se presentaron con una mediana de 4 años antes de la TAK. Conclusiones: varios reportes y series de casos relatan la superposición entre estas dos enfermedades. Si bien las mismas podrían compartir cierta base genética común, todavía no contamos con evidencia sólida que permita estimar que esta asociación no es casual.

https://doi.org/10.47196/rar.v34i3.745

14.

Contribuciones a la implementación de sistemas electrónicos digitales embebidos sobre hardware reconfigurable
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Cabrera Sarmiento, Alejandro José

; Garcés Socarrás, Luís Manuel

; Cabrera Aldaya, Alejandro

; Cuiman Márquez, Raudel

; Sánchez Solano, Santiago

; Brox Jiménez, Piedad

; Ieno Junior, Egidio

; Cleber Pimenta, Tales

; Bob Brumley, Billy

Anales de la Academia de Ciencias de Cuba

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Dic 2023, Volumen 13 Nº 4 elocation e1482

Resumen: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: Embedded electronic systems on reconfigurable hardware devices make it possible to carry out hybrid hardware/software implementations that allow higher latency functions to be speeded up by hardware, which is why the development of parameterizable hardware architectures that allow their use in various applications is a current field of research. The objective of this work is to expose different contributions in this field related with the acceleration of image processing functions and cryptographic functions, as well as on the detection of possible vulnerabilities against different types of attacks. Methods: They are presented different development methodologies due to the diversity of the contributions that are staged. It was used for the implementation of the image processing functions, a model-based methodology, making use of the Xilinx System Generator tool together with Matlab/Simulink, as well as a new automatic configuration procedure for the hardware components of the developed library, while they were developed the implementations of the cryptographic functions in hardware description language. For the detection of vulnerabilities, they were used content manipulation and collateral channel attacks for power consumption of the SPA type. Results: The use of hardware components of the library developed in a vehicle license plate identification application and hardware components of cryptographic functions, duly protected against different attacks, in the ARCANO cryptographic system, as well as the validation that the Binary Euclidean Algorithm is vulnerable to partial knowledge of its execution flow. Conclusions, they are emphasized the fundamental contributions of the research results, as well as their practical utility in real applications.

RESUMEN Introducción: Los sistemas electrónicos embebidos sobre dispositivos de hardware reconfigurable posibilitan la realización de implementaciones híbridas hardware/software que permiten acelerar mediante hardware las funciones de mayor latencia, por lo que constituye un campo de investigación actual el desarrollo de arquitecturas hardware parametrizables que posibiliten su utilización en diversas aplicaciones. El objetivo de este trabajo es presentar diferentes contribuciones en este campo relacionadas con la aceleración de funciones de procesamiento de imágenes y funciones criptográficas, así como en la detección de posibles vulnerabilidades ante diferentes tipos de ataques. Métodos: Se presentan diferentes metodologías de desarrollo dada la diversidad de las contribuciones que se exponen. Para la implementación de las funciones de procesamiento de imágenes se utilizó una metodología basada en modelos haciendo uso de la herramienta Xilinx System Generator junto con Matlab/Simulink así como un novedoso procedimiento de configuración automática de los componentes hardware de la biblioteca desarrollada; mientras que las implementaciones de las funciones criptográficas fueron desarrolladas en lenguaje de descripción de hardware. Para la detección de las vulnerabilidades se utilizaron ataques de manipulación de contenidos y de canal colateral por consumo de potencia del tipo SPA. Resultados: Se expone la utilización de componentes hardware de la biblioteca desarrollada en una aplicación de identificación de matrículas de vehículos y de componentes hardware de funciones criptográficas, debidamente protegidas contra diferentes ataques, en el sistema criptográfico ARCANO, así como la validación de que el algoritmo binario de Euclides es vulnerable ante el conocimiento parcial de su flujo de ejecución. En Conclusiones se enfatizan las contribuciones fundamentales de las investigaciones realizadas, así como su utilidad práctica en aplicaciones reales.

15.

Programas de prevención del consumo de sustancias psicoactivas en contextos escolares: una revisión sistemáticabold>
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Benavides Mora, Vanessa Katherine

; Ayala Ibarra, Karen Melissa

; Coral Riascos, Natalia

Diversitas: Perspectivas en Psicología

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Dic 2023, Volumen 19 Nº 2 Paginas 44 - 54

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Abstract The Consumption of Psychoactive Substances is a problem worldwide, the consequences of which are still considerable, therefore, interest in its study is constantly increasing, seeking to reduce the risks and consequences associated with it through preventive strategies. The objective of this study is focused on identifying the scientific advances developed between 2010 and 2019 in terms of the implementation of prevention programs for the use of Psychoactive Substances (SPA) in school contexts. To achieve this objective, the specific systematic review methodology is used, a search for scientific articles is carried out in eight databases, considering the inclusion and exclusion criteria. Based on the different scientific advances found, it is recommended to take these results into account for the design and implementation of SPA prevention programs, as they can guide an adequate process of these, leading to significant solutions.

Resumen El consumo de sustancias psicoactivas es una problemática a nivel mundial, cuyas consecuencias siguen siendo considerables. Por tanto, el interés en su estudio aumenta constantemente y busca disminuir los riesgos y consecuencias asociadas por medio de estrategias preventivas. El objetivo del presente estudio se centra en identificar los avances científicos desarrollados entre los años 2010 a 2019 sobre la implementación de programas de prevención del consumo de sustancias psicoactivas (SPA) en contextos escolares. Para lograr dicho objetivo, se empleó la metodología específica de revisión sistemática, se realizó la búsqueda de artículos científicos en ocho bases de datos, teniendo en cuenta los criterios de inclusión y exclusión. A partir de los diferentes avances científicos encontrados, se recomienda tener en cuenta estos resultados para el diseño e implementaciones de programas de prevención de SPA, pues pueden guiar un adecuado proceso y dar lugar a soluciones significativas.

https://doi.org/10.15332/22563067.9370

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