Abstract This article discusses impasses in the process of deinstitutionalizing madness, based on the results of a census conducted in Private Therapeutic Residences in a municipality in southern Brazil. These residences, viewed as contemporary asylums that still exist contrary to the law and current mental health policies in the country, reflect on the fate of lives subjected to asylum practices in such establishments, ones considered unworthy of mourning. What has been identified is that the intensification of the asylum logic results from counter-reformist forces updated within the context of Brazilian psychiatric reform. This conservative movement is particularly observed in segregating practices in mental health related to the care of people who use alcohol and other drugs. The resulting reflection calls for the need to build strategies to reinvent the anti-asylum struggle in light of our current challenges, which reaffirms greater attention with respect to freedom as a non-negotiable premise.

Resumo Este artigo discute impasses ao processo de desinstitucionalizaçao da loucura a partir dos resultados de um censo em Residenciais Terapêuticos Privados de um município no sul do Brasil. Apreendidos enquanto asilos contemporâneos, ainda existentes a contrapelo da Lei e da política de saúde mental vigentes no país, reflete-se sobre o destino de vidas manicomializadas em tais estabelecimentos, consideradas vidas não passíveis de luto. Identificou-se que a intensificação da lógica manicomial resulta das forças contrarreformistas atualizadas no contexto da reforma psiquiátrica brasileira. Este movimento conservador é especialmente observado em práticas segregadoras em saúde mental relacionadas ao cuidado de pessoas que fazem uso de álcool e outras drogas. A reflexão daí decorrente convoca à necessidade de construção de estratégias de reinvenção da luta antimanicomial mediante os desafios de nosso tempo, reafirmando o cuidado em liberdade como premissa inegociável.

Résumé Cet article discute les impasses du processus de désinstitutionnalisation de la folie, à partir des résultats d’un recensement dans des Résidences Thérapeutiques Privées d’une municipalité du sud du Brésil. Pris en compte comme des asiles contemporains encore existants à contre-courant de la loi et des politiques de santé mentale en vigueur dans le pays, il est question du destin des vies de personnes institutionnalisées dans de tels établissements, considérées comme des vies non dignes de deuil. On a identifié que l’intensification de la logique asilaire découle des forces contre-réformistes actualisées dans le contexte de la réforme psychiatrique brésilienne. Ce mouvement conservateur est particulièrement observé dans les pratiques de ségrégation en santé mentale liées aux soins des personnes qui consomment de l’alcool et d’autres drogues. La réflexion qui en découle appelle à la nécessité de construire des stratégies pour réinventer la lutte anti-asilaire face aux défis actuels, réaffirmant le soin en liberté comme une prémisse non négociable.

ABSTRACT In recent years the concern of environmentalists has been growing due to the large use of products that have non-renewable fossil sources as raw material. An alternative adopted by the researchers is the production of thermoplastic matrix composites with lignocellulosic waste fibers. The oticica or oiti is a fruit rich in oil and is widely used for soap production. The co-product generated from this process is rich in fiber, oil and impurities and is currently widely used for animal feed and soil fertilizer. The objective of the present work is the production and evaluation of the properties of HDPE composites with Oiticica waste. As matrix was used a green HDPE supplied by Braskem and the dispersed phase was the pie de oiticica supplied by a soap factory. Compositions with 5, 10 and 20% of waste de oiticica were processed by double screw extrusion and the specimens made by the injection process. The composites were characterized by uniaxial tensile test to evaluate mechanical properties (deformation to rupture, modulus, and stress at maximum force). The interaction between pie and matrix was analyzed through the fracture surface using scanning electron microscopy and the analysis. Thermal analysis was assessed by DSC. The results showed decrease in the deformation for 10 and 20% waste compositions. There was a gradual decrease at the stress at the maximum strength of the composites when compared to HDPE. The micrographs showed little interaction between fiber and matrix and the presence of voids. Thermal analysis showed a decrease in the degree of crystallinity, concluding that the presence of the oiticica may have made it difficult to organize the chains, generating a greater number of amorphous regions. nonrenewable non renewable material fibers coproduct co product fertilizer factory 5 1 20 rupture modulus force. force . force) DSC compositions voids crystallinity chains regions 2

RESUMO Nos últimos anos a preocupação de ambientalistas vem crescendo devido ao grande uso de produtos que tem como matéria-prima fontes fósseis não renováveis. Uma alternativa adotada entre os pesquisadores é a produção de compósitos de matriz termoplástica com fibras de resíduos de lignocelulósicas. A oiticica ou oiti é um fruto rico em óleo e é muito utilizado para a produção de sabão. O co-produto gerado desse processo é rico em fibras, óleo e impurezas e atualmente é muito utilizado para ração animal e adubo para solo. O objetivo do presente trabalho é a produção e avaliação das propriedades de compósitos de PEAD com Torta de Oiticica. Como matriz foi utilizado um PEAD verde fornecido pela Braskem e a fase dispersa foi a Torta de oiticica fornecida por uma fábrica de sabão. As composições com 5, 10 e 20% de Torta de oiticica foram processadas por extrusão dupla rosca e os corpos de provas confeccionados pelo processo de injeção. Os compósitos foram caracterizados através do ensaio de tração uniaxial para avaliação de propriedades mecânicas (deformação até a ruptura, módulo e tensão na força máxima). A interação entre torta e matriz foi analisada através da superfície de fratura utilizando microscopia eletrônica de varredura e a análise térmica foi avaliada através de DSC. Os resultados mostraram diminuição na deformação para composições com 10 e 20% de torta. Houve uma queda gradativa na tensão na força máxima nos compósitos quando comparada com a do PEAD. As micrografias mostraram pouca interação entre fibra e matriz e a presença de vazios. As análises térmicas apresentaram uma diminuição no grau de cristalinidade. concluindo-se que a presença da torta pode ter dificultado a organização das cadeias, gerando maior número de regiões amorfas. matériaprima matéria prima renováveis lignocelulósicas sabão coproduto co produto solo Oiticica 5 1 20 injeção ruptura máxima. . máxima) DSC vazios cristalinidade concluindose concluindo se cadeias amorfas 2

Abstract Objective To delineate the profile of preventive behavior against covid-19 adopted by older adults and investigate its correlation with social and health conditions. Method A cross-sectional and analytical study conducted with 72 individuals (≥ 60 years) enrolled in an Open University for Older Adults in the municipality of Campinas, São Paulo, Brazil. Participants were contacted via telephone from November 2020 to June 2021. A total of 11 preventive measures were scrutinized to identify the behaviors adopted by older adults against covid-19. Data analysis employed principal component analysis, Pearson's chi-square tests, and Fisher's exact tests, with a confidence level of 95%. Results The adoption of preventive behaviors was assessed through activities such as hand hygiene with soap and water, use of hand sanitizer, wearing facial masks, and practicing social distancing. The majority of individuals reported the adoption of preventive behaviors (79.2%), and it was observed that those with incomes below four minimum wages exhibited higher proportions of compliance (87.5%) compared to individuals with incomes exceeding 10 minimum wages (46.2%) (p=0.038). Conclusion Preventive measures against covid-19 were embraced by the older adults, influenced by income. The findings underscore the significance of educational strategies for fostering health preventive behaviors, taking into account the social context. covid19 covid 19 covid-1 conditions crosssectional cross sectional 7 ≥ ( 6 years Campinas Paulo Brazil 202 2021 1 covid19. 19. Pearsons Pearson s chisquare chi square tests Fishers Fisher 95 95% water sanitizer masks distancing 79.2%, 792 79.2% , 79 2 (79.2%) 87.5% 875 87 5 (87.5% 46.2% 462 46 (46.2% p=0.038. p0038 p p=0.038 . 0 038 (p=0.038) income context covid1 covid- 20 9 79.2 (79.2% 87.5 8 (87.5 46.2 4 (46.2 p003 p=0.03 03 (p=0.038 79. (79.2 87. (87. 46. (46. p00 p=0.0 (p=0.03 (79. (87 (46 p0 p=0. (p=0.0 (79 (8 (4 p=0 (p=0. (7 p= (p=0 (p= (p

Resumo Objetivo Descrever o perfil de comportamento preventivo contra covid-19 adotado pelas pessoas idosas e verificar sua relação com as condições sociais e de saúde. Método Estudo transversal e analítico realizado com 72 indivíduos (≥ 60 anos) cadastrados em uma Universidade Aberta para Pessoas Idosas, no município de Campinas, São Paulo, Brasil. Os participantes foram contatados por meio de ligações telefônicas, no período de novembro de 2020 a junho de 2021. Um total de 11 medidas preventivas foram analisadas para a identificação dos comportamentos adotados pelas pessoas idosas contra covid-19. Para a análise dos dados, utilizaram-se análise de componentes principais, testes qui-quadrado de Pearson e Exato de Fisher, com 95% de confiança. Resultados A adoção de comportamentos preventivos foi avaliada por meio das atividades de: higienização das mãos com água e sabão, uso do álcool em gel, uso de máscara facial e distanciamento social. A maioria dos indivíduos mencionou a adoção de comportamentos preventivos (79,2%), e verificou-se que aqueles com renda inferior a quatro salários-mínimos apresentaram maiores proporções de comportamento (87,5%) quando comparados aos indivíduos de renda superior a 10 salários-mínimos (46,2%) (p=0,038). Conclusão Houve adoção às medidas preventivas para covid-19 pelos idosos, influenciada pela renda. Os achados ressaltam a importância de estratégias educativas para promoção de comportamentos preventivos em saúde, considerando o contexto social. covid19 covid 19 covid-1 saúde 7 ≥ ( 6 anos Idosas Campinas Paulo Brasil telefônicas 202 2021 1 covid19. 19. dados utilizaramse utilizaram se principais quiquadrado qui quadrado Fisher 95 confiança sabão gel social 79,2%, 792 79,2% , 79 2 (79,2%) verificouse verificou saláriosmínimos salários mínimos 87,5% 875 87 5 (87,5% 46,2% 462 46 (46,2% p=0,038. p0038 p p=0,038 . 0 038 (p=0,038) idosos covid1 covid- 20 9 79,2 (79,2% 87,5 8 (87,5 46,2 4 (46,2 p003 p=0,03 03 (p=0,038 79, (79,2 87, (87, 46, (46, p00 p=0,0 (p=0,03 (79, (87 (46 p0 p=0, (p=0,0 (79 (8 (4 p=0 (p=0, (7 p= (p=0 (p= (p

Abstract Denture biofilm acts as a potential reservoir for respiratory pathogens, considerably increasing the risk of lung infections, specifically aspiration pneumonia, mainly 48h after hospital admission. The establishment of a straightforward, affordable, and applicable hygiene protocol in a hospital environment for the effective control of denture biofilm can be particularly useful to prevent respiratory infections or reduce the course of established lung disease. Objectives To evaluate the anti-biofilm effectiveness of denture cleaning protocols in hospitalized patients. Methodology The maxillary complete dentures (MCDs) of 340 hospitalized participants were randomly cleaned once using one of the following 17 protocols (n=20): brushing with distilled water, toothpaste, or neutral liquid soap (controls); immersion in chemical solutions (1% sodium hypochlorite, alkaline peroxide, 0.12% or 2% chlorhexidine digluconate), or microwave irradiation (650 W for 3 min) combined or not with brushing. Before and after the application of the protocols, the biofilm of the intaglio surface of the MCDs was evaluated using two methods: denture biofilm coverage area (%) and microbiological quantitative cultures on blood agar and Sabouraud Dextrose Agar (CFU/mL). Data were subjected to the Wilcoxon and Kruskal-Wallis tests (α=0.05). Results All 17 protocols significantly reduced the percentage area of denture biofilm and microbial and fungal load (P<0.05). The highest percentage reductions in the area of denture biofilm were observed for 1% hypochlorite solution with or without brushing and for 2% chlorhexidine solution and microwave irradiation only in association with brushing (P<0.05). The greatest reductions in microbial and fungal load were found for the groups that used solutions of 2% chlorhexidine and 1% hypochlorite and microwave irradiation, regardless of the association with brushing (P<0.05). Conclusions A single immersion for 10 min in 1% sodium hypochlorite, even in the absence of brushing, proved to be a straightforward, rapid, low-cost, and effective protocol for cleaning the dentures of hospitalized patients. pathogens pneumonia h admission straightforward affordable disease antibiofilm anti patients (MCDs 34 1 n=20 n20 n 20 (n=20) water toothpaste controls (controls) (1 peroxide 012 0 12 0.12 2 digluconate, digluconate , digluconate) 650 (65 methods % (% CFU/mL. CFUmL CFU/mL . CFU mL (CFU/mL) KruskalWallis Kruskal Wallis α=0.05. α005 α α=0.05 05 (α=0.05) P<0.05. P005 P P<0.05 (P<0.05) rapid lowcost, lowcost low cost, cost low-cost n=2 n2 (n=20 (controls ( 01 0.1 65 (6 (CFU/mL α00 α=0.0 (α=0.05 P00 P<0.0 (P<0.05 n= (n=2 0. 6 α0 α=0. (α=0.0 P0 P<0. (P<0.0 (n= α=0 (α=0. P<0 (P<0. (n α= (α=0 P< (P<0 (α= (P< (α (P

Dry decomposition, wet digestion, and dissolution in aqueous medium for direct analysis were evaluated for the preparation of eight samples of liquid and bar soap and one powder detergent for later determination of Cd, Mg, Pb, and Zn by inductively coupled plasma optical emission spectroscopy (ICP OES). The evaluation of the best conditions for digestion of the samples were chosen from a set of tests where conventional heating using 1 mol L-1 HNO3 with addition of 30% H2O2 proved to be the most effcient method. The average hydrodynamic diameter of 525 nm was determined using dynamic light scattering measurements. The concentrations found were: Cd and Pb (< limit of detection (LOD)), Mg (50.89 to 1119 μg g 1), and Zn (280.25 to 537.54 μg g 1). After evaluating the sample preparation methods, the accuracy of the methodology was verifed through recovery tests of analytes, obtaining values between 83 and 119% and a relative standard deviation (RSD) ≤ 4.30% (n = 6; 4 mg L 1). The LOD ranged from 0.015 to 0.5 µg g 1 and the limits of quantifcation (LOQ) from 0.045 to 2 µg g 1. The soaps and powder detergent samples studied here may be used without any harm to health as the contents were within the limits established by the legislation. decomposition ICP OES. OES . OES) L1 L- HNO 30 HO H O H2O method 52 measurements < ( LOD, , (LOD)) 50.89 5089 50 89 (50.8 111 1, 1) 280.25 28025 280 25 (280.2 53754 537 54 537.5 methods analytes 8 119 RSD (RSD 430 4.30 n 6 0015 0 015 0.01 05 5 0. LOQ (LOQ 0045 045 0.04 legislation 3 (LOD) 50.8 508 (50. 11 280.2 2802 28 (280. 5375 53 537. 43 4.3 001 01 0.0 004 04 (LOD 50. (50 280. (280 4. 00 (5 (28 (2

ABSTRACT Background: Children who experience alkaline injury are at risk for the development of esophageal strictures and the need for esophageal dilations. Objective: We aimed to assess predictors for a higher number of esophageal dilatations in children following alkali ingestion. Methods: Single-center retrospective cohort study including children who underwent esophagogastroduodenoscopy (EGD) after alkali ingestion. Possible predictive factors for the need for esophageal dilatations were evaluated. Results: A total of 34 patients were included, and 19 were female (55.9%). The median age at the time of the accidents was 20.6 months (IQR 15-30.7). All alkali ingestions were accidental, in all cases involving liquid products, and most (24/34; 70%) occurred at the child’s home. Homemade liquid soap was the agent in half of the cases. The most frequently reported symptom at presentation was vomiting (22/34, 64.7%). The median follow-up time was 3.2 years (IQR 1.1-7.4). On follow-up, the median number of esophageal dilatations required for these patients was 12.5 (IQR 0-34). Among demographic factors, male gender (P=0.04), ingestion of homemade products (P<0.01), and accidents happening outside of the household environment (P=0.02) were associated with a greater number of esophageal dilations on follow-up. An endoscopic classification Zargar of 2B or higher (P=0.03), the presence of stricture at the time of the second EGD (P=0.01), and gastroesophageal reflux disease (GERD) as a late complication (P=0.01) were also associated with a greater number of esophageal dilations on long term follow-up. Conclusion: Beyond the endoscopic classification severity - a well-known risk factor for the strictures after alkali ingestions, we found that male gender, accidents with homemade products, and accidents occurring outside the household environment were significantly associated with a greater number of esophageal dilatations in the long-term follow-up of children following alkali ingestion. Background Objective Methods Singlecenter Single center (EGD evaluated Results 3 included 1 55.9%. 559 55.9% . 55 9 (55.9%) 206 20 6 20. IQR 1530.7. 15307 15 30.7 30 7 15-30.7) accidental 24/34 2434 24 (24/34 70% 70 childs child s home 22/34, 2234 22 (22/34 64.7%. 647 64.7% 64 64.7%) followup follow up 32 2 3. 1.17.4. 1174 1.1 7.4 4 1.1-7.4) followup, up, 125 12 5 12. 034. 034 0 0-34) P=0.04, P004 P P=0.04 , 04 (P=0.04) P<0.01, P001 P<0.01 01 (P<0.01) P=0.02 P002 02 (P=0.02 followup. up. B P=0.03, P003 P=0.03 03 (P=0.03) P=0.01, P=0.01 GERD (GERD (P=0.01 Conclusion wellknown well known longterm 55.9 (55.9% 1530 1530.7 307 30. 15-30.7 24/3 243 (24/3 22/34 223 (22/3 64.7 17 1.17.4 117 11 1. 74 7. 1.1-7.4 0-34 P00 P=0.0 (P=0.04 P<0.0 (P<0.01 (P=0.0 (P=0.03 55. (55.9 153 1530. 15-30. 24/ (24/ 22/3 (22/ 64. 1.17. 1.1-7. 0-3 P0 P=0. P<0. (P<0.0 (P=0. (55. 15-30 (24 22/ (22 1.17 1.1-7 0- P=0 P<0 (P<0. (P=0 (55 15-3 (2 1.1- P= P< (P<0 (P= (5 15- ( (P< (P

RESUMO Contexto: Crianças que sofrem lesões cáusticas correm alto risco de desenvolver estenose esofágica e necessidade de dilatações esofágicas. Objetivo: Objetivamos avaliar preditores de necessidade de maior número de dilatações esofágicas em crianças, após uma ingestão cáustica. Métodos: Estudo de coorte retrospectivo de centro único incluindo crianças submetidas a esofagogastroduodenoscopia (EGD) após ingestão cáustica. Foram avaliados possíveis fatores preditivos para a necessidade de dilatações esofágicas. Resultados: Foram incluídos 34 pacientes, 19 do sexo feminino (55,9%). A idade mediana no momento dos acidentes foi de 20,6 meses (IQR 15-30,7). Todas as ingestões cáusticas foram incidentais, de substâncias líquidas, e a maioria dos acidentes (24/34; 70%) ocorreu no domicílio da criança. Em metade dos casos, a substância ingerida foi um sabão caseiro. O sintoma mais reportado na apresentação foi vômito (22/34 -64,7%). O tempo médio de acompanhamento foi de 3,2 anos (IQR 1,1- 7,4). No seguimento, o número médio de dilatações esofágicas necessárias foi de 12,5 (IQR 0-34). Entre os fatores demográficos, o sexo masculino (P=0,04), acidentes com produtos caseiros (P=<0,01) e a localização do acidente fora do ambiente domiciliar (P=0,02) foram associados a um maior número de dilatações esofágicas no seguimento. A classificação endoscópica Zargar 2B ou mais (P=0,03), a presença de estenose na segunda EGD (P=0,01) e a DRGE como complicação tardia (P=0,01) também se associaram a maior número de dilatações esofágicas no acompanhamento a longo prazo. Conclusão: Além da gravidade da classificação endoscópica - fator de risco bem conhecido para as estenoses após ingestão de cáusticos, observamos que o sexo masculino, os acidentes com produtos caseiros e os acidentes ocorridos fora do ambiente doméstico foram fatores significativamente associados a um maior número de dilatações esofágicas em acompanhamento em longo prazo de crianças após ingestão de soda cáustica. Contexto Objetivo cáustica Métodos (EGD Resultados 3 pacientes 1 55,9%. 559 55,9% . 55 9 (55,9%) 206 20 6 20, IQR 1530,7. 15307 15 30,7 30 7 15-30,7) incidentais líquidas 24/34 2434 24 (24/34 70% 70 criança casos caseiro 22/34 2234 22 (22/3 64,7%. 647 64,7% 64 -64,7%) 32 2 3, 1,1 11 7,4. 74 7,4 4 7,4) seguimento 125 12 5 12, 034. 034 0 0-34) demográficos P=0,04, P004 P P=0,04 , 04 (P=0,04) P=<0,01 P001 01 (P=<0,01 P=0,02 P002 02 (P=0,02 B P=0,03, P003 P=0,03 03 (P=0,03) P=0,01 (P=0,01 Conclusão cáusticos 55,9 (55,9% 1530 1530,7 307 30, 15-30,7 24/3 243 (24/3 22/3 223 (22/ 64,7 -64,7% 1, 7, 0-34 P00 P=0,0 (P=0,04 P=<0,0 (P=<0,0 (P=0,0 (P=0,03 55, (55,9 153 1530, 15-30, 24/ (24/ 22/ (22 64, -64,7 0-3 P0 P=0, P=<0, (P=<0, (P=0, (55, 15-30 (24 (2 -64, 0- P=0 P=<0 (P=<0 (P=0 (55 15-3 ( -64 P= P=< (P=< (P= (5 15- -6 (P

ABSTRACT Background Critically ill patients are at increased risk of health care-associated infections due to various devices (central line-associated bloodstream infection, catheter-associated urinary tract infection, and ventilator-associated pneumonia), which pose a significant threat to this population. Among several strategies, daily bathing with chlorhexidine digluconate, a water-soluble antiseptic, has been studied as an intervention to decrease the incidence of health care-associated infections in the intensive care unit; however, its ability to reduce all health care-associated infections due to various devices is unclear. We designed the Daily Chlorhexidine Bath for Health Care Associated Infection Prevention (CLEAN-IT) trial to assess whether daily chlorhexidine digluconate bathing reduces the incidence of health care-associated infections in critically ill patients compared with soap and water bathing. Methods The CLEAN-IT trial is a multicenter, open-label, cluster randomized crossover clinical trial. All adult patients admitted to the participating intensive care units will be included in the trial. Each cluster (intensive care unit) will be randomized to perform either initial chlorhexidine digluconate bathing or soap and water bathing with crossover for a period of 3 to 6 months, depending on the time of each center’s entrance to the study, with a 1-month washout period between chlorhexidine digluconate bathing and soap and water bathing transitions. The primary outcome is the incidence of health care-associated infections due to devices. The secondary outcomes are the incidence of each specific health care-associated infection, rates of microbiological cultures positive for multidrug-resistant pathogens, antibiotic use, intensive care unit and hospital length of stay, and intensive care unit and hospital mortality. Conclusion The CLEAN-IT trial will be used to study feasible and affordable interventions that might reduce the health care-associated infection burden in critically ill patients. careassociated associated central lineassociated line catheterassociated catheter ventilatorassociated ventilator pneumonia, pneumonia , pneumonia) population strategies watersoluble soluble antiseptic however unclear CLEANIT CLEAN IT (CLEAN-IT multicenter openlabel, openlabel open label, label open-label months centers center s 1month month 1 transitions multidrugresistant multidrug resistant pathogens use stay mortality

RESUMO Fundamentos Pacientes críticos têm maior risco de infecções relacionadas à assistência à saúde devido ao uso de vários dispositivos (infecção da corrente sanguínea associada a cateter central, infecção do trato urinário associada ao cateter e pneumonia associada à ventilação mecânica), o que representa uma ameaça significativa para essa população. Entre as várias estratégias, o banho diário com digluconato de clorexidina, um antisséptico solúvel em água, foi estudado como intervenção para diminuir a incidência de infecções relacionadas à assistência à saúde na unidade de terapia intensiva; no entanto, sua capacidade de reduzir todas as infecções relacionadas à assistência à saúde devido a vários dispositivos não está clara. Desenhamos o estudo Daily Chlorhexidine Bath for Health Care Associated Infection Prevention (CLEAN-IT) para avaliar se o banho diário com digluconato de clorexidina reduz a incidência de infecções relacionadas à assistência à saúde em pacientes críticos em comparação com o banho de água e sabão. Métodos O estudo CLEAN-IT é um estudo clínico multicêntrico, aberto, randomizado e em cluster com cruzamentos. Todos os pacientes adultos admitidos nas unidades de terapia intensiva participantes serão incluídos no estudo. Cada grupo (unidade de terapia intensiva) será randomizado para realizar o banho inicial com digluconato de clorexidina ou banho de água e sabão com cruzamento por um período de 3 a 6 meses, dependendo do momento de entrada de cada centro no estudo, com um período de washout de 1 mês entre os banhos com digluconato de clorexidina e as transições para os banhos de água e sabão. O desfecho primário é a incidência de infecções relacionadas à assistência à saúde devido a dispositivos. Os desfechos secundários são a incidência de cada infecção específica relacionada à assistência à saúde, as taxas de coleções microbiológicas positivas para microrganismos multirresistentes, o uso de antibióticos, o tempo de internação na unidade de terapia intensiva e no hospital e a mortalidade na unidade de terapia intensiva e no hospital. Conclusão O estudo CLEAN-IT será usado para estudar intervenções viáveis e acessíveis que possam reduzir a incidência de infecções relacionadas à assistência à saúde em pacientes em estado crítico. central mecânica, mecânica , mecânica) população estratégias entanto clara CLEANIT CLEAN IT (CLEAN-IT multicêntrico aberto cruzamentos meses multirresistentes antibióticos crítico

Abstract: The objective of this study was to characterize the morphological composition of five populations of native maize and estimate their yields using agricultural practices without the use of agrochemicals. The study conducted in 2021, in the municipality of Cintalapa, Chiapas, within the experimental field of the Regional Academic Center of the Antonio Narro Autonomous Agrarian University. The five populations of native maize were provided by farmers from different regions of the state, with prior informed consent. The Agricultural practices consisted of using plant extracts and potassium soap with neem extract (Azadirachta indica) to prevent and combat pests. For fertilization, Californian red earthworm (Eisenia foetida) leachate and bat guano were applied in their commercial presentation. Morphological characters were evaluated with a descriptive statistical analysis considering days to male and female flowering, plant and ear height ear length and diameter, number of rows per ear and number of kernels per row. Grain yield was estimated by the weight of the ear harvested from a random sample of 20 plants per population. Numerical differences of the studied variables were identified, which demonstrates an existing genetic diversity. The populations with the highest yields were Campeón and Olotillo, with 5.37 and 4.4 ton ha-1 (± 1.24), respectively. The data provide information to design native maize conservation strategies through agrochemical-free management.

Resumen: El objetivo de este estudio fue caracterizar morfológicamente cinco poblaciones de maíz nativo y estimar sus rendimientos, empleando prácticas agrícolas sin uso de agroquímicos. El estudio se realizó en el año 2021, en el municipio de Cintalapa, Chiapas, dentro del campo experimental del Centro Académico Regional de la Universidad Autónoma Agraria Antonio Narro. Las cinco poblaciones de maíz nativo fueron proporcionadas por campesinos de diferentes regiones de la entidad, con previo consentimiento informado. Las prácticas agrícolas consistieron en uso de extractos vegetales y jabón potásico con extracto de neem (Azadirachta indica) para la prevención y combate de plagas. Para la fertilización se aplicó lixiviado de lombriz roja californiana (Eisenia foetida) y guano de murciélago en su presentación comercial. Los caracteres morfológicos se evaluaron con un análisis estadístico descriptivo considerando: días de floración masculina y femenina, alturas de planta y mazorca, longitud y diámetro de la mazorca, y número de hileras por mazorca y número de granos por hilera. El rendimiento de grano se estimó mediante el peso de la mazorca cosechada de una muestra aleatoria de 20 plantas por población. Se identificaron diferencias numéricas de las variables estudiadas, lo que demuestra una diversidad genética existente. Las poblaciones que presentaron mayores rendimientos fueron Campeón y Olotillo, con 5,37 y 4,4 ton ha-1 (± 1,24), respectivamente. Los datos aportan información para diseñar estrategias de conservación de maíces nativos con manejo libre de agroquímicos.

Abstract This article aims at discussing aspects related to the context of the decline of television, approaching Latin American television studies with other theories about television. In this study, we focus our discussion on Globoplay, Grupo Globo's streaming platform - the largest Brazilian media conglomerate. Our analysis investigates Grupo Globo's project to recover old soap operas as a media and marketing strategy for the streaming platform. Based on a theoretical discussion, the study believes that Brazilian television has found ways to guarantee its existence due to platformisation. On the assumption that the socialising character is a major advantage of television, this study questions whether television would be losing its socialising function to the detriment of new media cultures. In fact, we observe that social television and participatory culture employ elements that aggregate and reconfigure this current phase of television, described as a hypertelevision by some authors, such as Scolari (2009). With this in mind, we may not be witnessing television's decline but its new essence. In addition to mobilizing consumption, the return of old soap operas promotes the socialization of the collective nostalgic feeling generated by these productions on social networks. It is evident that the platform has explored this reciprocal relationship between nostalgia and convergence culture to consolidate itself in the Brazilian streaming scenario. In light of these notes, we believe that affective memory has a considerable impact on the strategies employed by the platform, functioning as a profitable and effective mechanism for the survival of Brazilian television.

Resumo Este artigo tem como objetivo discutir aspetos relacionados ao contexto do declínio da televisão numa aproximação dos estudos televisivos latino-americanos com outras teorias a respeito da televisão. Neste estudo, focamos nossa discussão na Globoplay, plataforma de streaming do Grupo Globo - o maior conglomerado mediático brasileiro. A nossa análise investiga o projeto de resgate de telenovelas antigas do Grupo Globo como estratégia mediática e mercadológica da plataforma de streaming. A partir de uma discussão teórica, o estudo acredita que a televisão brasileira tem encontrado formas de garantir a sua existência por meio da plataformização. A partir da premissa de que o grande trunfo da televisão seja a sua função socializadora, este estudo questiona se a televisão está a perder esse aspeto em detrimento das novas culturas mediáticas. De facto, observamos que a TV social e a cultura participativa empregam elementos que agregam e reconfiguram essa atual fase da televisão, descrita como uma hipertelevisão por alguns autores, como Scolari (2009). Com isso em mente, estamos a assistir não ao declínio da televisão, mas à sua nova essência. Além de mobilizar o consumo, a volta das novelas antigas promove nas redes sociais a socialização da nostalgia coletiva gerada por essas produções. O presente artigo evidencia como a plataforma explora essa relação recíproca entre nostalgia e cultura da convergência para se consolidar no cenário do streaming brasileiro. Diante desses apontamentos, acreditamos que a memória afetiva desempenha um impacto considerável nas estratégias empregadas pela plataforma, de modo a funcionar como um mecanismo rentável e eficaz para a sobrevivência da televisão brasileira.

Resumen Con el fin de investigar el efecto de cuatro biosólidos de las industrias láctea, maltera, jabonera y papelera sobre el crecimiento y producción de biomasa de plántulas de Vicia faba L., se realizaron mezclas de biosólido:suelo en proporciones 20:80, 40:60 y 60:40. Se realizaron análisis fisicoquímicos y microbiológicos a cada biosólido y las mezclas. Los biosólidos mostraron diferencias en la presencia (NMP) de coliformes fecales de 3 a 1 100 Salmonella sp., de 2 a 3 y de 0 a 16 huevos de helmintos por g de sólidos totales. La concentración (mg kg-1) de metales pesados en cobre fue de 0.7 a 1.9, cromo de 0.8 a 2.4, cadmio de 0 a 0.6, zinc de 4.3 a 8.6, níquel 1.2 a 3.8 y plomo 1.3 a 5.7, sin arsénico y mercurio. Los contaminantes fueron inferiores a los límites permisibles según la SEMARNAT (2002), además, entre los biosólidos el pH varió de 7 a 9.8 y la materia orgánica (MO) de 0.3 a 6.2%. Los biosólidos de la industria láctea y malta incorporados al suelo modificaron el pH de 8.1 a 7.4, incrementaron la MO de 1.2 a 3.5%, el nitrógeno total de 7 a 35 mg kg-1 y el fósforo disponible de 5 a 25 mg kg-1. A 30 días después de la siembra en invernadero, las plántulas de V. faba que crecieron en suelo con el biosólido de la industria láctea en la mayor proporción incrementaron la producción de biomasa en 1 145% y la longitud en 342%.

Abstract In order to investigate the effect of four biosolids from the dairy, malt, soap and paper industries on the growth and production of biomass of Vicia faba L. seedlings, biosolid:soil mixtures were made in ratios 20:80, 40:60 and 60:40. Physicochemical and microbiological analyses were performed on each biosolid and mixtures. Biosolids showed differences in the presence (MPN) of fecal coliforms from 3 to 1 100, Salmonella sp., from 2 to 3 and from 0 to 16 helminth eggs per g of total solids. The concentration (mg kg-1) of heavy metals in copper was from 0.7 to 1.9, chromium from 0.8 to 2.4, cadmium from 0 to 0.6, zinc from 4.3 to 8.6, nickel from 1.2 to 3.8 and lead from 1.3 to 5.7, without arsenic and mercury. The contaminants were below the permissible limits according to SEMARNAT (2002), in addition, among biosolids the pH varied from 7 to 9.8 and organic material (OM) from 0.3 to 6.2%. Biosolids from the dairy and malt industries incorporated into the soil modified the pH from 8.1 to 7.4, increased OM from 1.2 to 3.5%, the total nitrogen from 7 to 35 mg kg-1 and the available phosphorus from 5 to 25 mg kg-1. At 30 days after sowing in the greenhouse, V. faba seedlings grown in soil with the biosolid from the dairy industry in the highest ratio increased biomass production by 1 145% and length by 342%.

The limit equilibrium model, used in displacement discontinuity codes, is a popular method to simulate pillar failure. This paper investigates the use of physical modelling to calibrate this model. For the experiments, an artificial pillar material was prepared and cubes were poured using the standard 100 mm χ 100 mm civil engineering concrete moulds. The friction angle between the cubes and the platens of the testing machine was varied by using soap and sandpaper. Different modes of failure were observed depending on the friction angle. Of interest is that significant loadshedding was recorded for some specimens which visually remained mostly intact. This highlights the difficulty of classifying pillars as failed or intact in underground stopes where spalling is observed. The laboratory models enabled a more precise calibration of the limit equilibrium model compared to previous attempts. Guidelines to assist with calibration of the model are given in the paper. The limit equilibrium model appears to be a useful approximation of the pillar failure as it could simulate the stress-strain behaviour of the laboratory models.

RESUMEN Este artículo propone reflexionar sobre el proyecto de retorno de las antiguas telenovelas del Grupo Globo en la plataforma de streaming Globoplay para discutir su impacto en la constitución y mantenimiento de la(s) memoria(s). En este esfuerzo investigativo, se movilizan el método bibliográfico exploratorio, utilizando el enfoque cualitativo, y el método de análisis inductivo. Los hallazgos de la investigación permiten ver el archivo televisivo más allá de la fuerza de mercadotecnia contenida en el proyecto de devolución de telenovelas antiguas. Parece que el rescate de estas obras actúa como un medio para evocar, potenciar y, sobre todo, mantener los recuerdos. s la(s memorias. memorias memoria . memoria(s) investigativo exploratorio cualitativo inductivo evocar todo recuerdos memoria(s

ABSTRACT This article aims to propose a reflection on the return project of Grupo Globo’s old soap operas, on the Globoplay streaming platform, discussing its impact on the constitution and maintenance of memory(s). To that end, the exploratory bibliographic method, using the qualitative approach, and the inductive analysis method were used. The date found by the research allow us to see the television archive beyond the marketing force contained in the project to return the old soap operas. It appears that the rescue of these productions acts as a means of evoking, enhancing, and, above all, maintaining memories. Globos Globo s operas platform memorys. memorys memory . memory(s) end approach used evoking enhancing all memories memory(s

RESUMO Este artigo propõe uma reflexão acerca do projeto de retorno das telenovelas antigas do Grupo Globo na plataforma de streaming Globoplay, discutindo sobre seu impacto na constituição e manutenção da(s) memória(s). Para isso, foram empregados o método bibliográfico exploratório, utilizando-se da abordagem qualitativa, e o método de análise indutivo. Os dados obtidos com a pesquisa permitem enxergar o arquivo televisivo além da força mercadológica contida no projeto de retorno das telenovelas antigas. Verifica-se que o resgate dessas obras atua como meios de evocação, potencialização e, sobretudo, manutenção das memórias. Globoplay s da(s memórias memória . memória(s) isso exploratório utilizandose utilizando se qualitativa indutivo Verificase Verifica evocação sobretudo memória(s

Resumen Macrodactylus nigripes (Bates) es una plaga que ataca el cultivo del maíz causando pérdidas económicas en la producción. Con la finalidad de encontrar alternativas agroecológicas para su manejo, el objetivo fue evaluar el efecto de la aplicación de Argemone mexicana L., Ricinus communis L, Beauveria bassiana (Bals) Vuill y Metharrizium anisoplae (Metschnikoff) Sorokin, así como colecta de M. nigripes con red de golpeo en el cultivo de maíz. El experimento se realizó bajo un diseño de bloques completamente al azar con cuatro repeticiones, donde se probaron los cinco métodos de control y fueron comparados con el tratamiento testigo (agua). R. communis y A. mexicana disminuyeron significativamente la infestación de plantas por M. nigripes, aumentando la producción en 36 y 30% respectivamente. Estos resultados demuestran que ambos tratamientos alternados con jabón zote pueden ser una buena alternativa del manejo de esta especie plaga.

Abstract Macrodactylus nigripes (Bates) is a pest that attacks corn crops, causing economic losses in production. In order to find agroecological alternatives for its management, the objective was to evaluate the effect of the application of Argemone mexicana L., Ricinus communis L, Beauveria bassiana (Bals) Vuill and Metharrizium anisoplae (Metschnikoff) Sorokin, as well as the collection of M. nigripes with a beating net in corn crops. The experiment was conducted under a completely randomized block design with four repetitions, where the five control methods were tested and compared with the control treatment (water). R. communis and A. mexicana significantly decreased plant infestation by M. nigripes, increasing production by 36% and 30%, respectively. These results show that both treatments alternated with zote soap can be a good alternative for the management of this pest species.

Abstract The formation of biofilm on denture bases is a recurrent clinical problem that favors the development of denture stomatitis. The effectiveness of a hygiene protocol in a 3D-printed denture base resin is still uncertain. Objective To evaluate of the effectiveness of immersion, associated or not with brushing in a soap solution, on the biofilm control of a 3D-printed denture base resin. Methodology Specimens of denture base resins [Cosmos Denture (COS) and Classico (CLA/control)] were contaminated in vitro with Candida albicans and immersed in sodium hypochlorite 0.25% (SH, alkaline peroxide) AP, chlorhexidine digluconate 2% (CD or PBS-Control), associated or not with brushing with 0.78% Lifebuoy soap. Roughness was evaluated before and after brushing and immersion. The effectiveness of the protocols was assessed by CFU/mL, cellular metabolism (XTT), scanning electron microscopy (SEM), and confocal scanning laser microscopy. Data were analyzed by T student, ANOVA/Welch, and Tukey/Gomes–Howell pos-hoc tests (α = 0.05). Results CLA showed greater roughness than COS. CFU/mL and XTT were higher in COS resin with a higher hyphae formation. Immersion in SH and CD eliminated CFU/mL and reduced XTT for both resins, associated or not with brushing. AP reduced CFU/mL only when associated with brushing. Conclusions The biofilm on the 3D-printed resin was thicker and presumably more pathogenic, regardless of its smoother surface. Immersions in SH 0.25% and CD 2% are effective hygiene protocols for both resins, associated or not with brushing. AP should be recommended when associated with brushing with a Lifebuoy 0.78% solution. stomatitis 3Dprinted Dprinted 3D printed D uncertain immersion solution Cosmos (COS CLA/control CLAcontrol (CLA/control) 025 0 25 0.25 SH, (SH peroxide 2 PBSControl, PBSControl PBS Control , PBS-Control) 078 78 0.78 CFUmL CFU mL XTT, (XTT) SEM, SEM (SEM) student ANOVAWelch ANOVA Welch ANOVA/Welch TukeyGomesHowell Tukey Gomes Howell poshoc pos hoc α 0.05. 005 0.05 . 05 0.05) pathogenic surface (CLA/control 02 0.2 PBS-Control 07 7 0.7 (XTT (SEM 00 0.0 0.

ABSTRACT Purpose: Demonstrate the pivotal role of environmental information amongst all the project collaborators and to present the products resulting from the processing of recycling materials. Method: The research is pragmatic, and the main tool used was an open interview with four of the street collectors, out of a team of 12 members, and their manager. The location of the research was the “Gota do Óleo” Association in Eunápolis, Bahia, Brazil. Result: The results demonstrate that “Gota do Óleo” Association has an important role in the education of the local community concerning environmental information. It also demonstrates the importance of the association as a source of income for the families of the local street collectors. They use credible environmental information from official agencies and disseminate quality information in their social media platforms. The main products from the association are: brooms, clothesline ropes, bottles and soap. The association also promotes conferences on environmental education in schools and private companies. Conclusion: There is a visible vacuum relative to the involvement of public libraries and professionals of information technology to mediate reliable environmental information to the general public, while this is a fertile field for their work. Local initiatives are crucial for rescuing the ecosystem, and an important source of income for the families. Purpose materials Method pragmatic collectors 1 members manager Gota Óleo Eunápolis Bahia Brazil Result platforms brooms ropes soap companies Conclusion work ecosystem

RESUMO Objetivo: Demonstrar como a informação ambiental permeia o trabalho dos colaboradores do projeto e apresentar os produtos advindos do processamento dos materiais recicláveis. Método: A pesquisa é qualitativa, o instrumento utilizado foi a entrevista aberta com quatro catadores e o gestor, sendo a população de 12 catadores. O lócus da pesquisa foi a Associação Gota do Óleo, em Eunápolis, na Bahia. Resultado: Os resultados demonstraram que a associação exerce uma função importante na educação ambiental da população e é também importante fonte de renda para as famílias de catadores, utilizando informação ambiental de qualidade advinda principalmente de órgãos oficiais e disseminado informação de qualidade em suas redes sociais. Os principais produtos da associação são: vassoura, vassourão, cordas de varal de garrafas pet e sabão. A associação promove também palestras em escolas e empresas, com a finalidade de educação ambiental. Conclusões: Percebe-se um vazio quanto à atuação de bibliotecas e profissionais da informação, sendo este um campo fértil para a atuação dos mesmos enquanto mediadores da informação ambiental de qualidade. Iniciativas locais são imprescindíveis para a recuperação do ecossistema, bem como importante fonte de renda para as famílias. Objetivo recicláveis Método qualitativa gestor 1 Óleo Eunápolis Bahia Resultado sociais vassoura vassourão sabão empresas Conclusões Percebese Percebe se ecossistema