Stand-up documentary-the inclusion of video film footage in stand-up performances-is a growing trend in comedy specials. Gary Gulman in The Great Depresh and Whitmer Thomas in The Golden One are some of the earliest comedians to employ documentary clips in creating portraits of their real-life circumstances on stage. More recently, Yvonne Orji's comedy special for Home Box Office (HBO) entitled Momma, I Made It! also utilizes documentary video films of the comedienne's experience in Nigeria to bring the Nigerian experience closer to her American audience. In this article I bring to the academic mainstream the understudied subject of stand-up documentary in humour studies. Through close reading and nuanced analyses of the gig, I examine stand-up documentary as a novel device of narration through which Orji introduces her audience to life in Nigeria through an exposition of her experiences growing up. Accentuating the differences between Nigerians and Americans and playing on Nigerian stereotypes, the comedienne deploys the clips as precise proofs transitioning her American audience into the alternate Nigerian contexts in Momma, I Made It! I conclude that stand-up documentary enhances the credibility of the performance, shapes perceptions of Nigerians, and facilitates audience understanding of cultural contexts that would otherwise remain unfamiliar to them.

Abstract The goal of this work is to identify new fatty acid-mimetic 99mTc-complexes to be used as myocardial imaging agents that allow studying heart abnormalities in high-risk patients. In this sense, we designed a fatty acid-mimetic substructure including an amide moiety that, among other properties, could improve myocardial residence time. A diamide with a chain length of 15 atoms and porting a 6-hydrazinonicotinyl (HYNIC) chelator, and an analog with a short carbon-chain, were prepared with convergent organic synthetic procedures and radiolabeled with 99mTc using tricine as the sole coligand. The in vivo proofs of concept were performed using healthy mice. The new 99mTc-complexes were obtained with adequate radiochemical purity. The lipophilicities were in agreement with the length of the chains. While both 99mTc-complexes showed uptake in the myocardial muscle, the designed radiopharmaceutical with the longest chain length had preferential target-uptake and target-retention compared to other complexes described in the bibliography. Further studies, involving imaging assays, synthetic modifications, and assay of new coligands for 99mTc-HYNIC complexes, are currently ongoing. acidmimetic acid mimetic 99mTccomplexes mTccomplexes mTc highrisk high risk patients sense properties time 1 6hydrazinonicotinyl hydrazinonicotinyl 6 HYNIC (HYNIC chelator carbonchain, carbonchain carbon chain, carbon-chain coligand mice purity chains muscle targetuptake target targetretention retention bibliography studies assays modifications 99mTcHYNIC mTcHYNIC ongoing

Abstract This paper presents the strategies and initial implementations of a data culture conversion process at a company in the electricity sector. Solutions are being developed within the scope of the construction management macro-process, which involves multiple sectors of the company, as well as external agents. The strategy is based on implementing Proofs of Concept as tools for converting the data culture within the company and, at the same time, supporting the essential activities of construction management. The proofs of concept aligned with the change in data culture have two components: technology and people. The first consists mainly of intelligent automation and process optimization. The second component involves sensitization, training and developing solutions together with the company's employees. The results involve a reduction in workload since some activities have been partially or totally transferred to the software. Greater assertiveness in estimating numerical data, such as prices and budgets. Increased reliability by reducing human intervention and complex calculations. Greater controllability by monitoring multiple activities and sectors, simplifying management. Finally, the integration of technology and people has shown significant advances in organizational culture, enabling employees to have a greater understanding of advanced tools and methods and to be able to identify opportunities and share solutions within the company. sector macroprocess, macroprocess macro process, macro-process agents time components optimization sensitization companys s software budgets calculations Finally

Abstract: The question of defining a Jaśkowski-Fitch natural deduction system for modal logic has been settled since the very introduction of such formalisms in the middle of the last century. In contrast, a sequent-style formulation of this approach has only been discussed since the turn of this century but exclusively from the point of view of type theories. In this paper we propose a substructural sequent-style deductive system, based on previous ideas by Borghuis and Clouston, which captures Fitch-style for modal logic in a faithful way, meaning that the features of the original diagrammatic proofs are enforced by the sequent rules. This answers the question of what is a sequent-style version of Fitch-style natural deduction in the case of the necessity fragment of minimal modal logic S 4.

Resumo Este artigo discute formas de contribuição para o aprimoramento do senso crítico dos educandos em sala de aula de Matemática. Especificamente, para fins de promoção dessa modalidade de pensamento chamada senso crítico, expusemos um grupo de alunos de 6º ano a um ambiente de argumentações e refutações, aplicando uma sequência de atividades didáticas que os conduzissem a demonstrar o seguinte resultado da Geometria Plana: “a soma dos ângulos internos de qualquer triângulo é 180°”. Assim, a seguir, usando este resultado, determinassem o valor da soma dos ângulos internos de um polígono qualquer por um processo de inferência lógica. Em relação às tarefas, que envolveram a explicitação de validações, os estudantes foram incentivados a fazer manipulações, produzir questionamentos e levantar hipóteses, visando construir conhecimentos e relações necessárias, tornando, dessa forma, os aprendizados significativos. Para fundamentar nossos trabalhos, apoiamo-nos na teoria do desenvolvimento do pensamento geométrico proposta por Van Hiele, bem como em Balacheff e nos seus trabalhos sobre argumentações e refutações para a construção de validações matemáticas. Para a análise dos resultados, embasamo-nos em Carraher e seus critérios para caracterizar um indivíduo como pensador crítico. Mostramos, assim, que o desenvolvimento do senso crítico pode ser favorecido por meio de um trabalho pedagógico que envolva os alunos na construção de validações geométricas. Matemática Especificamente º Plana 180°. 180 180° . 180°” Assim seguir lógica tarefas manipulações hipóteses necessárias tornando forma significativos apoiamonos apoiamo Hiele matemáticas resultados embasamonos embasamo Mostramos assim geométricas 18 1

Abstract In the present paper, we evaluated how to contribute to the improvement of critical sense of the students in the mathematics classes. Specifically, for the purpose of promoting this way of thinking, named critical sense, we exposed a group of 6th grade students to an environment of argumentations and refutations applying a sequence of didactic activities that leads them to demonstrate the result of Plane Geometry: “the sum of the internal angles of any triangle is 180°”. Next, using this result, that they determined the sum of the internal angles of any polygon through a process of logical inference. In the tasks, which involved the communication of validations, the students were encouraged to make manipulations, to question, and to raise hypotheses, always aiming to build the necessary knowledge and geometric relationships, making their learning meaningful. To support our actions, we relied on Van Hiele and his theory on the development of geometric thinking, as well as on Balacheff and his works whereby him explore argumentations and refutations to the construction of mathematic validations. In analyzing the results, we based ourselves on Carraher and his criteria to characterize an individual as a critical thinker. Thus, we show that the development of critical thinking can be favored through pedagogical work that involves students in the construction of geometric validations, while observing the geometric learning levels proposed by Van Hiele. paper classes Specifically th Geometry 180°. 180 180° . 180°” Next inference tasks validations manipulations question hypotheses relationships meaningful actions results thinker Thus 18 1

Abstract This paper aims to correct recent results on a generalized class of ϝ −contractions in the context of b−metric spaces. The significant work consists of repairing some novel results involving ϝ −contraction within the structure of b-metric spaces. Our objective is to take advantage of the property (F1) instead of the four properties viz. (F1), (F2), (F3) and (F4) applied in the results of Nazam et al. [“Coincidence and common fixed point theorems for four mappings satisfying (αs, F)−contraction", Nonlinear Anal: Model. Control., vol. 23, no. 5, pp. 664-690, 2018]. Our approach of proving the results utilizing only the condition (F1) enriches, improves, and condenses the proofs of a multitude of results in the existing state-of-art.

Resumen Este artículo tiene por objetivo corregir resultados recientes sobre una clase generalizada de ϝ −contracciones en el contexto de b−espacios métricos. El trabajo significativo consiste en reparar algunos resultados nuevos que involucran ϝ −contracciones en la estructura de b-espacios métricos. Nuestro objetivo es aprovechar la propiedad (F1) en vez de las cuatro propiedades viz. (F1), (F2), (F3) y (F4) aplicadas en los resultados de Nazam et al. [“Coincidence and common fixed point theorems for four mappings satisfying (αs, F)−contraction", Nonlinear Anal: Model. Control, vol. 23, no. 5, pp. 664-690, 2018]. Nuestro enfoque para probar los resultados usando solo la condición (F1) enriquece, mejora y condensa las demostraciones de una multitud de resultados en el estado del arte existente.

RESUMEN: La discusión sobre pureza del método suele enfatizar el estudio de demostraciones particulares de la práctica matemática. Una crítica a esta posición cuestiona el valor de la pureza al afirmar que el “progreso matemático” depende esencialmente del empleo de métodos impuros. Este artículo muestra que una perspectiva más holística, centrada en cómo las demandas de pureza pueden operar en la construcción de teorías autónomas, permite identificar un contexto donde la pureza del método adquiere valor en la práctica matemática. En particular, se muestra la relevancia de tales demandas en el caso de las teorías algebraicas de números de Kronecker y Dedekind.

SUMMARY: The discussion of purity of method usually emphasizes the study of particular proofs of mathematical practice. A critique of this position questions the value of purity by claiming that “mathematical progress” depends essentially on the use of impure methods. This article shows that a more holistic perspective, focusing on how purity claims can operate in the construction of autonomous theories, allows us to identify a context where purity of method acquires value in mathematical practice. In particular, the relevance of such demands is shown in the case of Kronecker’s and Dedekind’s algebraic number theories.

RESUMO A crítica que o jovem Marx dirige contra a religião, em geral, e contra o argumento ontológico, em particular, constitui um ponto de intersecção entre a filosofia marxiana e a fenomenologia radical de Michel Henry. Ao rejeitar a noção de um Deus transcendente, bem como as provas racionais da sua existência, o Marx de Henry refuta, por um lado, todas as críticas da religião que se situam na esfera da pura racionalidade como permite, por outro, conceber uma religiosidade assente na noção de um Deus radicalmente imanente. geral ontológico particular transcendente existência refuta lado permite outro imanente

ABSTRACT The critique that the young Marx addresses against religion, in general, and against the ontological argument, in particular, constitutes a point of intersection between the Marxian philosophy and Michel Henry’s radical phenomenology. On the one hand, by rejecting the notion of a transcendent God as well as the rational proofs of his existence, Henry’s interpretation of Marx refutes all critiques of religion that lie in the sphere of pure rationality. On the other hand, from this hermeneutic of Marx arises a conception of a religiosity based on the notion of a pure immanent God. general argument particular Henrys Henry s phenomenology hand existence rationality

A desigualdade de Bell expôs um dos aspectos mais fundamentais da mecânica quântica: a teoria é incompatível com a forma usual de se interpretar conceitos básicos como realidade e localidade. Embora o argumento original de Bell não seja de difícil compreensão, existem maneiras mais acessíveis de demonstrar desigualdades similares. Neste artigo apresentamos duas dessas demonstrações, propostas por Nick Herbert e Asher Peres, ambas muito simples e, ao que parece, relativamente pouco conhecidas apesar de seu interesse pedagógico. Também discutimos como a localidade e elementos de realidade descritos por variáveis ocultas se manifestam nessas demonstrações. quântica compreensão similares demonstrações Peres parece pedagógico

Bell’s inequality exposed one of the most fundamental aspects of quantum mechanics: the theory is incompatible with the usual way of interpreting basic concepts such as reality and locality. Although Bell’s original argument is not difficult to follow, there are more accessible ways to demonstrate similar inequalities. In this article we present two of these proofs, proposed by Nick Herbert and Asher Peres, both very simple and, it seems, relatively little known despite their pedagogical interest. We also discuss how locality and elements of reality described by hidden variables are introduced in these proofs. Bells Bell s mechanics follow inequalities proofs Peres seems interest

ABSTRACT This work is concerned with the Cauchy problem for a Zakharov system with initial data in Sobolev spaces H k ( ℝ d ) × H l ( ℝ d ) × H l - 1 ( ℝ d ). We recall the well-posedness and ill-posedness results known to date and establish new ill-posedness results. We prove C 2 ill-posedness for some new indices ( k , l ) ∈ ℝ 2. Moreover, our results are valid in arbitrary dimension. We believe that our detailed proofs are built on a methodical approach and can be adapted to obtain similar results for other systems and equations. . wellposedness well posedness illposedness ill Moreover dimension equations

Abstract COVID-19 can converge with the pro-inflammatory immunoregulatory mechanisms of chronic lung diseases. Given the disorders inherent to lung transplantation and the inexistence of other definitive therapeutic alternatives, Adipose tissue-derived Stem Cells (ASCs) presented themselves as a therapeutic hope. The purpose of this review is to assess the basis for the potential use of ASCs in lung diseases unresponsive to conventional therapy, relating to their possible use in COVID-19 ARDS. 35 studies comprised this review, 14 being narrative reviews, 19 preclinical trials and two proofs of concept. COVID-19 can converge with the pro-inflammatory immunoregulatory mechanisms of chronic lung diseases. In view of the disorders inherent to lung transplantation and the inexistence of definitive therapeutic alternatives, Adipose tissue-derived Stem Cells (ASCs) presented themselves as a therapeutic hope. Its detailed reading indicated the absence of serious adverse effects and toxicity to the administration of ASCs and suggested possible effectiveness in reducing lung damage, in addition to promoting the recovery of leukocytes and lymphocytes with its immunomodulatory and anti-apoptotic effects. The revised clinical data suggests optimism in the applicability of ASCs in other immunoinflammatory diseases and in severe COVID-19 ARDS. However, further studies are needed to develop a consensus on the methods of collection of ASCs, the ideal dosage schedule, the most effective time and route of administration, as well as on the definition of indications for the administration of ASCs in cases of COVID-19 for conducting clinical trials in near future. COVID19 COVID COVID-1 proinflammatory pro inflammatory alternatives tissuederived tissue derived (ASCs hope therapy ARDS 3 1 reviews concept damage antiapoptotic anti apoptotic However schedule future COVID1 COVID-

Resumen (Objetivo) El presente artículo tiene por objetivo evidenciar la competencia algebraica exhibida por un grupo de 27 estudiantes de universidad, en México, al trabajar con una tarea algebraica. Para esto se propone, desde las investigaciones de la competencia matemática y los niveles de algebrización, un marco para su estudio articulado en tres acciones: resolver, interpretar y validar. (Metodología) La investigación fue de corte cualitativa y exploratoria con una selección de estudiantes de tipo incidental, la implementación de la tarea se llevó a cabo durante una clase habitual con duración de dos horas. El profesor titular y el investigador estuvieron presentes durante el desarrollo de la tarea en el aula. (Resultados) Los resultados muestran que estos estudiantes presentan dificultades en la acción de resolver dado que no manipulan eficazmente expresiones simbólico-literales y no alcanzan el nivel de algebrización esperado. También, presentan inconsistencias en la acción de interpretar, es decir, no identifican ni conectan los conocimientos sobre las propiedades de las operaciones que se ponen en juego en la tarea algebraica. En la acción de validar, comunican comprobaciones o verificaciones de carácter descriptivo. (Conclusiones) Los hallazgos sugieren que la mayoría de los participantes no alcanzaron un primer nivel de competencia algebraica y se plantea la necesidad de formular estadios de desarrollo basados en las tres acciones.

Resumo (Objetivo) O objetivo deste artigo é demonstrar a competência algébrica exposta por um grupo de 27 estudantes universitários no México quando se trabalha com uma tarefa algébrica. Para este fim, propomos, a partir da pesquisa sobre competência matemática e níveis de algebrização, uma estrutura para seu estudo articulada em três ações: resolver, interpretar e validar. (Metodologia) A pesquisa foi de coorte qualitativa e exploratória com uma seleção incidental de estudantes, a implementação da tarefa foi realizada durante uma aula regular com duração de duas horas. O professor principal e o pesquisador estiveram presentes durante o desenvolvimento da tarefa na sala de aula. (Resultados) Os resultados mostram que estes estudantes apresentam dificuldades na ação de resolver, uma vez que não manipulam efetivamente as expressões simbólico-literárias e não atingem o nível de algebrização esperado. Além disso, mostram inconsistências na ação de interpretar, ou seja, não identificam e nem conectam o conhecimento sobre as propriedades das operações em jogo na tarefa algébrica. Na ação de validar, eles relatam testes ou verificações de caráter descritivo. (Conclusões) As constatações sugerem que a maioria dos participantes não atingiu um primeiro nível de competência algébrica e surge a necessidade de formular etapas de desenvolvimento com base nas três ações.

Abstract (Objective) The present article seeks to determine the algebraic competence displayed by a group of 27 university students in Mexico when they worked on an algebraic problem. A study framework is proposed based on the investigation of mathematical competence and levels of algebrization in three areas: solving, interpreting and validating. (Methodology) A qualitative and exploratory study with convenience-based selection of students was implemented during a regular two-hour class. The professor and the researcher were present when the task was carried out in the classroom. (Results) The results show that the students had difficulties in problem solving because they did not effectively manipulate symbolic-literal expressions, and did not achieve the expected level of algebraization. They were also inconsistent in interpreting the task - that is, they did not identify or connect knowledge about the properties of the operations necessary to solve the algebraic problem. When validating their responses, they provided descriptive proofs or verifications. (Conclusions) The findings suggest that most of the participants did not display a basic level of algebraic competence, and the necessity of formulating stages of development based on the three actions is discussed.

Abstract This study constitutes part of a wider research project that aims to characterise how research mathematicians construct conjectures and mathematical proofs whilst carrying out research. From the philosophy of mathematics and mathematics education itself, a growing number of recommendations suggest studying the community of mathematics researchers and, in particular, the mathematical practices of these professionals, since it is understood that pertinent and accurate knowledge of these practices forms an essential source of information for the design of mathematics instruction. This paper focuses on the mathematical practice of proving and aims to advance in the characterisation of the mathematical activities undertaken by a research mathematician when constructing mathematical proofs. A qualitative methodology is used herein. Specifically, this work forms part of a case study on a female research mathematician who carries out research in the field of mathematical analysis. The empirical data collection was carried out in this case study via four semi-structured recorded interviews. The present study, which was carried out in two phases, has revealed what the participant in this study uses and creates, in the terms of Rasmussen et al. (2005), when constructing mathematical proofs. These findings highlight the essential role examples play in this mathematical practice and show how such examples facilitate the transition between empirical and deductive reasoning. Furthermore, the results of this work have been employed in the characterisation of mathematical proofs based on generic examples in a research context.

Resumen Este trabajo forma parte de una investigación más amplia que tiene por objeto caracterizar cómo construyen conjeturas y demostraciones matemáticas los investigadores en matemáticas cuando investigan. Desde la filosofía de las matemáticas y la propia educación matemática, son cada vez más numerosas las recomendaciones que sugieren estudiar a estos investigadores y, en concreto, sus prácticas matemáticas, ya que se entiende que un conocimiento adecuado y preciso de las mismas supone una muy valiosa fuente de información para al diseño de la instrucción en matemáticas. Este estudio pone el foco en la práctica matemática de demostrar y tiene como objetivo avanzar en la caracterización de las actividades matemáticas que desarrolla una investigadora en matemáticas cuando construye demostraciones matemáticas. La metodología de este trabajo es cualitativa. Concretamente, este estudio forma parte de un estudio de casos con una investigadora en matemáticas que desarrolla su investigación en análisis matemático. La recogida de datos empíricos se desarrolló durante cuatro entrevistas semiestructuradas, que fueron grabadas. El presente estudio, que se ha llevado a cabo en dos fases, ha permitido mostrar qué usa y qué crea (en términos de RASMUSSEN et al., 2005) la informante del caso cuando construye demostraciones matemáticas. Estos hallazgos resaltan el importante papel que juegan los ejemplos en esta práctica matemática y ponen de manifiesto cómo tales ejemplos facilitan la transición entre lo empírico y lo deductivo. Además, los resultados de este trabajo se han utilizado para caracterizar las demostraciones matemáticas basadas en ejemplos genéricos en un contexto de investigación.

Abstract The effect of sound vibration (SV) towards plants has been studied for more than 30 years. Many results have confirmed that SV influenced various parts of plants, e.g. the stomata. However, the scientific community is still in doubt of these results. Hence, it is now a matter of giving further proofs and/or insights using new methods. This study aimed to determine the stomata pore movement influenced by SV with new observation and analysis technique based on the edge detection method. We directly observed the abaxial stomata of Rhoeo discolor plant exposed by single SV frequencies from 0 to 7000 Hz with an interval of 1000 Hz. The main device used in the observation was a microscope. The observation was conducted before, during, and after the SV exposure. The measurement of the stomata pore area utilized an image capture, which was then analyzed with edge detection technique. These edges were used as an indicator in the calculation of the stomata pore area in the pixel unit. The result showed that SV with frequency of 6000 Hz produced the largest stomata pore area, whereas the frequencies of 2000 Hz and 3000 Hz gave smaller stomata pore areas. Therefore, based on the edge detection analysis a single frequency of SV influenced the stomata pore area.

Abstract Introduction: Halting ventilation during cardiopulmonary bypass (CPB) is implemented to operate in a less bleeding setting. It sustains a better visualization of the operation area and helps to perform the operation much more comfortably. On the other hand, it may lead to a series of postoperative lung complications such as atelectasis and pleural effusion. In this study, we investigated the effects of low tidal volume ventilation on inflammatory cytokines during CPB. Methods: Twenty-eight patients undergoing cardiovascular surgery were included in the study. Operation standards and ventilation protocols were determined and patients were divided into two groups: patients ventilated with low tidal volume and non-ventilated patients. Plasma samples were taken from patients preoperatively, perioperatively from the coronary sinus and postoperatively after CPB. IL-6, IL-8, TNF-α and C5a levels in serum samples were studied with enzyme-linked immunosorbent assay (ELISA) kits. Results: C5a, IL-6, IL-8 and TNF-α were similar when compared to the low tidal volume ventilated and non-ventilated groups (P>0.05) Comparing the groups by variables, IL-6 levels were increased during CPB in both groups (P=0.021 and P=0.001), and IL-8 levels decreased in the ventilation group during CPB (P=0.018). Conclusion: Our findings suggest that low tidal volume ventilation may reduce the inflammatory response during CPB. Although the benefit of low tidal volume ventilation in CPB has been shown to decrease postoperative lung complications such as pleural effusion, atelectasis and pneumonia, we still lack more definitive and clear proofs of inflammatory cytokines encountered during CPB.