Phosphate species can affect aquatic ecosystems, as excess of this nutrient can cause eutrophication, generating environmental impacts. Lamellar double hydroxides have shown promise in removing phosphate at low concentrations (10-50 mg L 1). In this context, lamellar double hydroxides were synthesized interspersed with nitrates and humic substances, searching for a new product that favors phosphorus adsorption. X-ray diffraction showed the presence of characteristic peaks of lamellar double hydroxides and thermogravimetric analysis showed the decomposition behavior of lamellar structure. The adsorption capacity occurred quickly (< 30 min), being more efficient for lamellar double hydroxides with NO3. The maximum adsorption capacity showed results of 35.03 and 44.20 mg g 1 for lamellar double hydroxides with humic substances and lamellar double hydroxides with NO3, respectively. The complexation capacity showed that pH directly influences complexation, being greater for lamellar double hydroxides with humic substances at pH 6.5. Thus, nanostructured materials with humic substances are promising for use in contaminant remediation and adsorption can be a fast and efficient technique for use in soil and water. ecosystems eutrophication impacts 1050 10 50 (10-5 1. . 1) context Xray X ray structure < ( 3 min, min , min) NO3 NO 3503 35 03 35.0 4420 44 20 44.2 respectively 65 6 5 6.5 Thus water 105 (10- 350 0 35. 442 4 2 44. 6. (10 (1

Parthenolide (PTN) is a secondary metabolite of the plant Tanacetum parthenium (L.) Schulz Bip. and is considered the chemical marker of this species. This sesquiterpene lactone (germacrene skeleton) has been described as responsible for the biological activity of the leaf extract. In addition, several studies in the literature have demonstrated its antiparasitic and antineoplastic activity. However, there is a need for knowledge of other safety parameters, such as pharmacokinetic, pharmacodynamic and toxicity evaluations. Therefore, in this investigation, the in vitro metabolism of parthenolide was performed with rat liver microsomes and biomimetic metabolism (such as cytochrome P-450 system) using organometallic catalysts. The biomimetic procedure was validated since the major compound of biomimetic oxidative reaction with meta-chloroperbenzoic acid catalyzed by metalloporphyrin 5,10,15,20-tetrakis(pentafluorophenyl)-porphyrin iron(III) chloride was also observed with rat liver microsomes. Previous chemoenzymatic synthesis studies of PTN afforded the same epoxide formation, this major oxidative compound was isolated and fully characterized as (1 R,10R)-epoxyparthenolide based on experimental and theoretical calculations of infrared (IR) and vibrational circular dichroism (VCD) data at the B3PW91/6-311G. Furthermore, for the first time, this metabolite was evaluated for trypanocidal and leishmanicidal activity. The mean inhibitory concentration (IC50) values were lower for PTN than its metabolite and showed significant cytotoxic effects for both parasites. This finding holds promise for addressing neglected diseases. (PTN L. L (L. Bip species germacrene skeleton extract addition However parameters pharmacokinetic evaluations Therefore investigation P450 P 450 P-45 system catalysts metachloroperbenzoic meta chloroperbenzoic 5,10,15,20tetrakispentafluorophenylporphyrin 5101520tetrakispentafluorophenylporphyrin tetrakispentafluorophenylporphyrin 5,10,15,20 tetrakis pentafluorophenyl porphyrin 5 10 15 20 ironIII iron III iron(III formation 1 ( R,10Repoxyparthenolide R10Repoxyparthenolide RRepoxyparthenolide R,10R epoxyparthenolide R 10R IR (IR VCD (VCD B3PW91/6311G. B3PW916311G BPWG B3PW91/6 311G. B3PW91 6 311G B PW G B3PW91/6-311G Furthermore time IC50 IC (IC50 parasites diseases (L P45 45 P-4 20tetrakispentafluorophenylporphyrin 5101520 5,10,15,2 2 10Repoxyparthenolide Repoxyparthenolide R10R RR 6311G B3PW91/6311G B3PW916 BPW B3PW91/ B3PW9 IC5 (IC5 P4 4 P- 510152 5,10,15, B3PW (IC 51015 5,10,15 5101 5,10,1 510 5,10, 51 5,10 5,1 5,

RESUMEN Este trabajo tiene por objetivo presentar un método de evaluación y análisis de la cadena de suministro como estructura organizativa cuya salida es un producto de calidad y alta demanda en el sector agropecuario. Se presentan definiciones, así como los elementos que definen a la cadena de suministro como estructura organizativa. Se brinda un método de evaluación y análisis, estableciendo sus dimensiones de trabajo y las etapas para su desarrollo. Su aplicación práctica permite realizar una síntesis de los factores que entorpecen y/o facilitan la efectividad de la cadena en el contexto de la economía cubana. Se expone el resultado del proyecto de investigación «Mejorar la cadena de suministro de productos cárnicos del sector agroalimentario para la exportación en fronteras. Código: PN131SS014-011», perteneciente a un Programa Nacional de Ciencia y Técnica.

ABSTRAC This work aims to present a method of evaluation and analysis of the supply chain as an organizational structure whose output is a quality product and high demand in the agricultural sector. Definitions are presented, as well as the elements that define the supply chain as an organizational structure. An evaluation and analysis method is provided, establishing its dimensions of work and the stages for its development. Its practical application allows a synthesis of the factors that hinder and/or facilitate the effectiveness of the chain in the context of the Cuban economy. The result of the research project «Improving the supply chain of meat products in the agri-food sector for export at borders Code PN131SS014-011», belonging to add files National Program of Science and Technique

Resumo O artigo tem como objetivo avaliar efeitos econômicos das aquisições da agricultura familiar, no âmbito do Programa Nacional de Alimentação Escolar (PNAE), para os municípios mineiros. De cunho quantitativo, o método escolhido é a regressão linear múltipla. Foram estimados quatro modelos, em que as variáveis econômicas, Produto Interno Bruto (PIB) total, agropecuário, indústria e serviços, são dependentes; o volume de repasses do PNAE (em reais) para agricultura familiar é a variável independente de interesse; e os valores (em reais) do crédito rural por meio do Programa de Fortalecimento da Agricultura Familiar (PRONAF), a produção da agroindústria familiar rural e o número de estabelecimentos da agricultura familiar vinculados a cooperativas ou associações são variáveis independentes de controle. Os principais resultados indicam que a variável PNAE mostrou-se estatisticamente significativa a 1% para os PIBs total, indústria e serviços, e estatisticamente significativo a 10% para o PIB agropecuária, apresentando maior efeito sobre o PIB total. Isso significa que as aquisições da agricultura familiar, por meio do PNAE, exercem efeitos econômicos positivos sobre esses setores e, principalmente, sobre o PIB total. Sugerem-se, para pesquisas futuras, estudos comparativos, aplicações de outras técnicas quantitativas e estudos com abordagens qualitativas. Recomendam-se também pesquisas que contemplem outras lentes teóricas para a percepção dos efeitos da política pública. , (PNAE) mineiros quantitativo múltipla modelos econômicas (PIB total agropecuário serviços dependentes reais interesse PRONAF, PRONAF (PRONAF) controle mostrouse mostrou se 1 10 agropecuária principalmente Sugeremse, Sugeremse Sugerem se, Sugerem-se futuras comparativos qualitativas Recomendamse Recomendam pública (PNAE (PRONAF

Abstract The article aims to evaluate the economic effects of purchases form family farming, under the Brazilian School Feeding Program (PNAE), for the municipalities of Minas Gerais. Of quantitative nature, the chosen method is the multiple linear regression. Four models were estimated, in which the variables are total Gross Domestic Product-GDP (PIB), agriculture and cattle ranching GDP (PIB agropecuário), industry GDP (PIB indústria), and services GDP (PIB serviços). As dependent variables were chosen: the volume of PNAE transfers (in Reais) for family agriculture as the independent variable of interest; the values (in Reais) of rural credit through the Brazilian Program Strengthening Program for Family Farming (PRONAF), the production of family farming agro-industry and the number of family farming establishments linked to cooperatives or associations as the independent control variables. The main results indicate that the independent variable PNAE was statistically significant at 1% for total GDP, industry GDP and services GDP, and statistically significant at 10% for the agriculture and cattle ranching GDP, showing greater effect on total GDP. This means that purchases from family farming , through the PNAE, have positive economic effects on these sectors and, especially, on the total GDP. It is recommended for future researches comparative studies, the application of other quantitative techniques and studies with qualitative approaches. We also recommend research that includes other theoretical lenses for the perception of the effects of public policy. (PNAE) Gerais nature regression estimated ProductGDP Product PIB, PIB (PIB) agropecuário, agropecuário agropecuário) indústria, indústria indústria) serviços. serviços . serviços) Reais interest PRONAF, PRONAF (PRONAF) agroindustry agro 1 10 especially approaches policy (PNAE (PRONAF

Resumen El artículo tiene como objetivo evaluar los efectos económicos de las compras de la agricultura familiar, en el marco del Programa Nacional de Alimentación Escolar (PNAE), para los municípios de Minas Gerais, Brasil. De carácter cuantitativo, el método elegido es la regresión lineal múltiple. Se estimaron cuatro modelos, en los que las variables el Producta Interno Bruto (PIB) total, el PIB de la agricultura y la ganadería, el PIB de la industria y el PIB de los servicios, son variables dependientes; el volumen de las transferencias del PNAE (en reales) para la agricultura familiar es la variable independiente de interés; y los valores (en reales) del crédito rural a través del Programa de Fortalecimiento de la Agricultura Familiar (PRONAF), la producción de la agroindustria familiar rural y el número de establecimientos de la agricultura familiar vinculados a cooperativas o asociaciones son las variables de control independientes. Los principales resultados indican que la variable PNAE, resultó estadístícamente significativa al 1% para el PIB total, la industria y los servicios, y estadístícamente significativa al 10% para el PIB agrícola y ganadero, presentando mayor efecto sobre el PIB total. Esto significa que las compras de la agricultura familiar tienen efectos económicos positivos en estos sectores. Se sugiere para futuras investigaciones estudios comparativos, la aplicación de otras técnicas cuantitativas y estudios con enfoques cualitativos. También recomendamos una investigación que incluya otras lentes teóricas para la percepción de los efectos de las políticas públicas. , (PNAE) Gerais Brasil cuantitativo múltiple modelos (PIB total ganadería servicios dependientes reales interés PRONAF, PRONAF (PRONAF) independientes 1 10 ganadero sectores comparativos cualitativos públicas (PNAE (PRONAF

Resumen Antecedentes: El uso racional del agua y la aplicación de sistemas de tratamiento para las aguas residuales se presentan como alternativa para subsanar la contaminación de los ecosistemas acuáticos. El IHPLUS® activado constituye una alternativa para la biorremediación de fuentes hídricas contaminadas. Objetivo. determinar la toxicidad por exposición única del producto IHPLUS® activado en larvas de Artemia sp. Métodos: Se evaluó la toxicidad por exposición única del bioproducto IHPLUS® activado en larvas de Artemia sp. obtenidas de quistes incluidos en agua de mar artificial. Los grupos experimentales de larvas de Artemia sp. fueron expuestos por 24 horas a cinco concentraciones del producto en estudio y se compararon con un grupo control sin exposición. Se calculó la CL50 del bioproducto y se estudió la influencia de factores que pudieran ser los responsables de la toxicidad/mortalidad, estos fueron la presencia o ausencia de micro-organismos y el pH. Resultados: La CL50 del producto resultó 0,042% en agua de mar artificial, por lo que se clasifica como no tóxico para crustáceos. Se demostró que el IHPLUS® activado resultó tóxico a concentraciones superiores a 0,032% en larvas de Artemia sp., bajo las condiciones del ensayo. El pH resultó ser el factor responsable en la producción de la toxicidad del bioproducto en Artemia sp. Conclusión: El IHPLUS® activado resultó no peligroso para crustáceos de ambientes marinos.

ABSTRACT Background: The rational use of water and the application of treatment systems for wastewater are presented as an alternative to remedy the contamination of aquatic ecosystems. The activated IHPLUS® constitutes an alternative for the bioremediation of contaminated water sources. The objective of the study was to determine the toxicity by single exposure of the activated IHPLUS® product in larvae of Artemia sp. Methods: Toxicity was evaluated by single exposure of the activated IHPLUS® bioproduct in Artemia sp. larvae obtained from cysts included in artificial seawater. The experimental groups of larvae were exposed for 24 hours to five decreasing concentrations of the product under study and were compared with a control group without exposure. The LC50 of the bioproduct was calculated as well as the influence of factors that could be responsible for the toxicity/mortality was studied, these were the presence or absence of micro-organisms and pH. Results: The LC50 of the product was 0,042% in artificial seawater, thus it is classified as non-toxic for crustaceans. It was shown that the activated IHPLUS® was toxic at concentrations higher than 0,032% in Artemia sp. larvae, under the test conditions. The pH turned out to be the responsible factor in the production of the toxicity of the bioproduct in Artemia sp. Conclusion: The activated IHPLUS® was not dangerous for crustaceans in marine environments.

ABSTRACT The Center of Molecular Immunology is an exponent of Cuban biotechnology institution dedicated to basic research, development, production and commercialization of biopharmaceuticals, with the aim of diagnosing and treating cancer and diseases related to the immune system. In this work, a bibliographic synthesis of research that was carried out in this center in the period from 2012 to 2018, was performed, with the purpose of analyzing the application of some Data Mining techniques in the evaluation of fermentation and purification stages of the process for obtaining biopharmaceuticals in three production facilities. The phases of Data Mining were characterized and the practical implication of the results was presented. Principal Components Analysis was applied as a descriptive model using THE UNSCRAMBLER software, and Artificial Neural Networks were applied as a predictive model using the MATLAB neural networks toolbox. The use of these models made it possible to extract useful information for decision making, thereby explaining the behavior of the parameters that influence the quality of the final product, as well as estimating important variables such as the concentration of the protein of interest in the fermentation supernatant and the performance of the purification stage, depending on the process variables that have the greatest influence on its behavior.

RESUMEN El Centro de Inmunología Molecular es una institución exponente de la biotecnología cubana dedicado a la investigación básica, desarrollo, producción y comercialización de biofármacos, con el objetivo de diagnosticar y tratar el cáncer, así como enfermedades relacionadas con el sistema inmune. En este trabajo se realizó una síntesis bibliográfica de investigaciones que se llevaron a cabo en este centro, en el periodo comprendido del 2012 al 2018, con el propósito de analizar la aplicación de algunas técnicas de Minería de Datos en la evaluación de las etapas de fermentación y purificación del proceso de obtención de biofármacos en tres instalaciones productivas. Se caracterizaron las fases de la Minería de Datos y se presentó la implicación práctica de los resultados. Se aplicó como modelo descriptivo el Análisis de Componentes Principales mediante el software THE UNSCRAMBLER, y como modelo predictivo las Redes Neuronales Artificiales con el empleo de la caja de herramientas de redes neuronales del MATLAB. La utilización de estos modelos permitió extraer información útil para la toma de decisiones, se logró con ello explicar el comportamiento de los parámetros que influyen en la calidad del producto final, así como estimar variables de importancia como la concentración de la proteína de interés en el sobrenadante de la fermentación y el rendimiento de la etapa de purificación, en función de las variables del proceso que mayor influencia tienen en su comportamiento.

ABSTRACT Due to the diversification of dairy products developed in the state of Falcón, the introduction of a fermented dairy product derived from yogurt combined with Aloe vera gel, a traditional crop of the region, is novel due to its nutritional properties and health benefits. The objective of this research was to evaluate the quality of a dairy drink with fermented aloe according to current regulations. Important authors such as Tamime and Robinson 1, Morillo and Toyo 2, Méndez and Romero 3 were taken as references. Product elaboration runs were carried out on a laboratory scale, in order to establish the adequate proportions of the fruity Aloe gel by mixing fruit pulp, sugar and Aloe gel, the most accepted being the 1:1:1 ratio. The physicochemical and microbiological characterization of the raw material and the finished product was carried out using the COVENIN standards and organoleptic tests to untrained judges to ensure the acceptance of the product, from which a fermented milk drink was obtained with the addition of 50 % gel of Fruity Aloe with a pH of 4,51; a titratable acidity of 0,837 % lactic acid; 3,64 % fat and 12,92 % non-fat solids. Regarding the microbiological quality, few yeasts and the absence of coliform bacteria were found, which complies with the physicochemical and microbiological requirements demanded by the regulations, allowing the obtaining of a quality product suitable for human consumption based on natural raw materials.

RESUMEN Debido a la diversificación de los productos de origen lácteo desarrollados en el estado Falcón, la introducción de un producto lácteo fermentado derivado del yogurt combinado con gel de Aloe vera, cultivo tradicional de la región, es novedoso por sus propiedades alimenticias y beneficios a la salud. Esta investigación tuvo como objetivo evaluar la calidad de una bebida láctea fermentada con gel de Aloe frutado según la normativa vigente. Se tomaron como referencias importantes autores como Tamime y Robinson, (1) Morillo y Toyo, (2) Méndez y Romero. (3) Se realizaron corridas de elaboración del producto a escala de laboratorio, a fin de establecer las proporciones adecuadas del gel de Aloe frutado mezclando pulpa de fruta, azúcar y gel de Aloe, siendo la más aceptada la proporción 1:1:1. Se realizó la caracterización fisicoquímica y microbiológica de la materia prima y del producto terminado mediante las normas COVENIN y pruebas organolépticas a 10 jueces no entrenados para asegurar la aceptación del producto, de donde se obtuvo una bebida láctea fermentada con la adición de 50 % de gel de Aloe frutado con un pH de 4,51; una acidez titulable de 0,837 % de ácido láctico; 3,64 % de grasa y 12,92 % de sólidos no grasos. Respecto a la calidad microbiológica se encontraron levaduras escasas y ausencia de bacterias coliformes, con lo cual se cumple con los requisitos fisicoquímicos y microbiológicos exigidos por la normativa, permitiendo la obtención de un producto de calidad apto para el consumo humano a base de materias primas naturales.

Over regions with sparse observation networks, including South Africa's Northern Cape Province, gridded data sets represent valuable supplementary data sources enabling spatially detailed climate investigations. Their performance is, however, influenced by regional characteristics, thus a performance assessment should be a prerequisite for any regional application. Through a pairwise comparison with eight point-based temperature records, we evaluated the AgERA5 data sets representation of mean summer (November-March; Tms) and winter (May-September; Tmw) temperatures and respective seasonal heatwave and coldwave characteristics across the Northern Cape for 1980-2020. Correlations ranging from 0.48 to 0.92 for Tms and from 0.38 to 0.94 for Tmw reflect relatively strong, but varying, temporal correspondence between the AgERA5 data and stations. Low biases, averaging -0.08 (0.17) °C and ranging from -0.79 to 2.10 (-0.40 to 1.47) °C for Tms (Tmw) were evident. Biases for the heatwave (coldwave) magnitudes were low, averaging -0.38 (0.19) °C², and ranging from -1.55 to 1.47 (-2.05 to 2.91) °C². Biases for the heatwave (coldwave) frequency were also low, but typically overestimated, averaging 1.19 (0.73) days, and ranging from -1.33 to 5.60 (-1.61 to 3.39) days. Biases for the heatwave (coldwave) number were low and typically overestimated, averaging 0.27 (0.08) events, and ranging from -0.28 to 1.40 (-0.39 to 0.39) events. Despite some stations depicting consistently poor performance, the study results support further application of the AgERA5 product for spatiotemporal analyses of mean and extreme temperatures across the Northern Cape, provided limitations are adequately acknowledged. Further application of the fine-resolution AgERA5 product will greatly inform impact-based studies exploring mean and extreme temperature influences over the Northern Cape Province. SIGNIFICANCE: • The AgERA5 product was assessed on its performance in representing average and extreme temperature characteristics over South Africa's Northern Cape Province. • Good comparability between the AgERA5 product and point-based observations supports further application of the AgERA5 across the Northern Cape. • The AgERA5 product offers a spatially detailed picture of mean and extreme temperatures across the Northern Cape, which is valuable for regions where weather stations are not available. • The AgERA5 product is thus important for impact-based studies assessing, for instance, the impact of extreme temperatures on livestock and human health.

Abstract Fungal contamination is an important problem in cannabis and medical cannabis production, as fungi can produce toxic compounds or reduce the quality and safety of the product. The aim of this study was to perform a bibliometric evaluation related to fungal contamination in cannabis, analyzing current trends in this field and providing future perspectives for research. For this purpose, an exhaustive search was carried out in the scientific literature in electronic databases such as Scopus and Web of Science (WOS), covering the period from 2000 to 2023. The results obtained were processed through bibliometrics and network analysis, using tools such as RStudio and Bibliometrix software. The results revealed that the main themes associated with fungal contamination in cannabis are focused on: diseases related to fungal contamination of the plant, use of fungi as an alternative biological control in cannabis cultivation, metabolites associated with cannabis and their potential in fungal control, as well as fungal diversity in cannabis cultivation and postharvest and the risk to consumer health. Finally, future research areas are proposed to address the challenge of fungal contamination in medicinal cannabis production, covering topics such as pest control, contamination, genetic resistance, active compounds, analysis methods, and the impact of fungi on cannabis.

Resumo A contaminação fúngica é um problema importante na produção da cannabis e cannabis medicinal, pois os fungos podem produzir compostos tóxicos ou reduzir a qualidade e a segurança do produto. O objetivo deste estudo foi realizar uma avaliação bibliométrica relacionada à contaminação fúngica na cannabis, analisando as tendências atuais nesse campo e fornecendo perspectivas futuras para a pesquisa. Para isso, foi realizada uma busca exaustiva na literatura científica em bases de dados eletrônicas como Scopus e Web of Science (WOS), abrangendo o período de 2000 a 2023. Os resultados obtidos foram processados por meio de bibliometria e análise de redes, utilizando ferramentas como o software RStudio e Bibliometrix. Os resultados revelaram que os principais temas associados à contaminação fúngica na cannabis estão focados em: doenças relacionadas à contaminação fúngica da planta, uso de fungos como alternativa de controle biológico no cultivo da cannabis, metabólitos associados à cannabis e seu potencial no controle de fungos, bem como a diversidade fúngica no cultivo e pós-colheita da cannabis e o risco à saúde dos consumidores. Por último, são sugeridas futuras áreas de pesquisa para enfrentar o desafio da contaminação fúngica na produção de cannabis medicinal, abordando temas como controle de pragas, contaminação, resistência genética, compostos ativos, métodos de análise e impacto dos fungos na cannabis.

Abstract Composting is one of the most applied biotechnological alternatives for the treatment and recovery of green waste (GW). However, its transformation is a challenge, due to the physicochemical characteristics of GWs that affect the process time and product quality. This limits the application of this technology in developing countries such as Colombia. This article presents contributions on the advances in GW composting research, based on results of six years of studies carried out by the authors of this paper. Reflections are addressed on: i) the analysis of the physicochemical quality of the substrates, ii) the evaluation of strategies to improve the process and the quality of the product, and iii) the perspectives on the alternatives implemented so far. The results of the investigations show that the strategies at different scales have been effective in reducing process times (between 43 and 67 days), improving the conditions for sanitizing the material (temperature in thermophilic ranges for a longer time -6 additional days- compared to treatments without strategies) and compliance with product quality standards. The reflection proposes new perspectives to continue with the studies of improvement of GW composting, among which issues associated with the use of co-substrates, additives, and bacterial inoculum are addressed, as well as the evaluation of product quality and employment of optimization tools in GW composting. These studies help position GW composting as a suitable option for the management of the lignocellulosic fraction present in municipal solid waste (MSW).

Resumen El compostaje es una de las alternativas biotecnológicas más aplicadas para el tratamiento y valorización de los residuos verdes (RV). Sin embargo, su transformación es un reto, debido a las características fisicoquímicas de los RV que afectan los tiempos del proceso y la calidad del producto. Esto limita la aplicación de esta tecnología en países en desarrollo como Colombia. Este artículo presenta aportes alrededor de los avances en la investigación del compostaje de RV, con base en resultados de seis años de estudios realizados por los autores. Se aborda una reflexión sobre: i) el análisis de la calidad fisicoquímica de los sustratos, ii) la evaluación de estrategias para mejorar el proceso y la calidad del producto, y iii) las perspectivas sobre las alternativas implementadas hasta el momento. Los resultados de las investigaciones muestran que las estrategias a diferentes escalas han sido efectiva para reducir los tiempos de proceso (entre 43 y 67 días), mejorar las condiciones para la higienización del material (temperatura en rangos termofílico por mayor tiempo (6 días adicionales) comparado con tratamientos sin estrategias) y un cumplimiento de los estándares de calidad del producto. La reflexión propone nuevas perspectivas para continuar con los estudios de mejoramiento del compostaje de RV, entre los que se abordan temas asociados a uso de co-sustratos, de aditivos, de inóculos bacterianos, así como la evaluación de la calidad del producto y el empleo de herramientas de optimización en el compostaje de RV. Estos estudios ayudan a posicionar el compostaje de RV como una opción adecuada para el manejo de la fracción lignocelulósica presente en los residuos sólidos municipales (RSM).

Abstract The quality of parts manufactured by thermoplastics injection molding can be evaluated based on product weight, appearance, and presence of defects. Furthermore, the conditions of the injection process can significantly influence the mechanical performance of the molded parts. Residual stresses generated during plastic processing may contribute to the formation of cracks or premature failures when the product is subjected to external loads or forces. This study aims to evaluate the effects of the injection process on an injected part and how they affect its mechanical performance. For this purpose, specimens were injected under different process conditions and, subsequently, employed in a. Some parts were also subjected to annealing (a thermal treatment) to induce molecular relaxation, which helps to reduce internal or residual stresses generated during the injection process. Additionally, a qualitative evaluation of the distribution of residual stresses in the injected parts was conducted using the s technique to complement and validate the results of the mechanical tests. The results of the specimens injected at a mold temperature of 50°C showed a greater release of residual stresses, as indicated in photoelasticity images analyzed here, and a noticeable increase in flexural strength if the heat treatment had been applied. This suggests that more residual stresses are produced at 50°C than at the recommended mold temperature of 80°C. The heat treatment significantly improved the mechanical performance of all the parts injected in this study under different processing conditions.

Resumen El grado de calidad de piezas fabricadas por inyección de termoplásticos se puede establecer por el peso del producto, apariencia y mínimos defectos. Adicionalmente, las condiciones del proceso de inyección pueden inducir un efecto en el desempeño mecánico de las piezas inyectadas, donde los esfuerzos residuales de la pieza inyectada generados en el procesamiento pueden promover la formación de grietas o fallas prematuras del producto durante su uso al aplicarle una carga o fuerza externa. El propósito del presente trabajo es evaluar el efecto que genera el procesamiento por inyección en una pieza inyectada en el desempeño mecánico de esta. Para tal fin, se inyectaron probetas bajo diferentes condiciones de proceso y posteriormente estas fueron sometidas a pruebas mecánicas de flexión, algunas piezas fueron llevadas a un tratamiento térmico de recocido “annealing”, con el fin de obtener una relajación molecular que permita reducir sus esfuerzos internos o residuales generados durante el proceso de inyección. Adicionalmente, se hizo una evaluación cualitativa de la distribución de esfuerzos residuales en las piezas inyectadas mediante la técnica de fotoelasticidad, para complementar y validar los resultados de las pruebas mecánicas. Se halló en los resultados de las muestras inyectadas a temperatura de molde de 50 ºC una mayor liberación de esfuerzos residuales de acuerdo con las imágenes de fotoelasticidad analizadas y un mayor porcentaje de incremento en la resistencia a la flexión de estas piezas al aplicar el tratamiento térmico. Lo que podría sugerir una mayor generación de esfuerzos residuales a esta temperatura de molde con respecto a la temperatura de molde recomendada de 80 ºC. El efecto de tratamiento térmico mejora significativamente el desempeño mecánico de todas las piezas evaluadas a las diferentes condiciones de proceso.

Abstract Recent events involving iron ore tailings dam collapses have emphasized the need for developing alternative ways of depositing tailings. This study aims to evaluate the effects of using three hydroxamates and a sulfosuccinamate as collectors in the direct flotation of iron ore tailings, using a bench flotation. The best result obtained on bench flotation was tested in a pneumatic cell. The sample used in this study (10.8% of Fe) consists of quartz and hematite. The Aero® 6494 Promoter hydroxamate showed the highest selectivity among the analyzed reagents, reaching 64.31% of Fe in the final product of the test with the < 150 µm sample. The possibility of using these reagents as constituents of a mixed collector with dodecylamine was also investigated. In this case, the Aero® 845 Promoter sulfosuccinamate yielded the best results, with 62.84% of Fe and 59.01% of metallurgical recovery of Fe. The synergistic effect between the two reagents might be explained by the stability of the monolayer formed by the intercalation of the ions from the dodecylamine and the Aero® 845 Promoter, which reduces the electrostatic repulsion between ions of the same species This mixed collector was tested in a pneumatic cell. However, it had a lower performance in terms of Fe metallurgical recovery than in a bench-scale cell test, mainly for the finest particles, due to the greater control of the process’s variables in the bench cell. 10.8% 108 10 8 (10.8 hematite Aero 649 6431 64 31 64.31 15 investigated case 84 results 6284 62 62.84 5901 59 01 59.01 However benchscale scale particles processs process s 10.8 1 (10. 643 6 3 64.3 628 62.8 590 5 0 59.0 10. (10 64. 62. 59. (1 (

ABSTRACT The advanced of tecnlogies and digital transformacion has increased software development, being relevant to achieve software quality. There are numerous types of software, all of them need software engineering, but each one has its own specificities. The present work shows a bibliografic search with the objective of identifying the main software categories, which will serve as a basis for future research to propose checklists for product evaluation according to categories.

RESUMEN El avance de las tecnologías y la transformación digital ha aumentado el desarrollo de software, siendo relevante lograr la calidad de los mismos. Existen numerosos tipos de software, todos necesitan ingeniería de software, pero cada uno tiene sus propias especificidades. El presente trabajo muestra una búsqueda bibliográfica con el objetivo de identificar las principales categorías de software, que servirá de base a futuras investigaciones para proponer de listas de verificación a la evaluación de producto de acuerdo a la categoría.

Abstract. One of the key features of mechanical seals is to achieve effective sealing between two mechanical parts to prevent displacement and coolant leakage in industrial applications. Currently most of these elements are produced using neoprene, compressed cardboard, tar paper, laminated graphite, so we sought to produce them using ABS and PLA materials. For the design we used CAD software with educational license intended for educators and researchers, then a finite element analysis is performed according to the specifications of the product. In this sense, the importance of FEM as an evaluation tool has been identified in the context of this trend of using innovative technologies for research. As part of the results, the data obtained allow the selection of both variables and physical properties of the connecting rod and can be used to develop projects and studies of this nature applicable in case studies related to mechanical, mechatronic, industrial and electronic engineering. Finally, the variables Factor of Safety (FS), Von Mises Stress (VM) and YZ Stress, are analyzed after simulation by FEM, providing a range of values for use in engineering applications with different techniques in which connecting rods are used, FS [ 0.55, 12.26], VM [1.63, 36.45], YZ [-1.36, 10.13]. As for the other results presented in this study, the correlation coefficient is used as a statistical part with graphs to evaluate the simulation, the dependence of variables and parameters relevant to the case study, so a strong relationship was observed between the variables; plane stress, deformation, displacement and Von Mises stress, whose values range between 0.87 and 0.99, showing a strong relationship between these variables and, for the others, it should be considered to improve the relationship and increase the coefficient.

Resumen. - Una de las características clave de los sellos mecánicos es lograr una estanqueidad efectiva entre dos piezas mecánicas para evitar el desplazamiento y las fugas de refrigerante en aplicaciones industriales. Actualmente la mayoría de estos elementos se producen utilizando neopreno, cartón comprimido, papel alquitranado, grafito laminado, por lo que buscamos producirlos utilizando materiales ABS y PLA. Para el diseño se utilizó software CAD con licencia educativa destinada a educadores e investigadores, posteriormente se realiza un análisis de elementos finitos según las especificaciones del producto. En este sentido, se ha identificado la importancia del FEM como herramienta de evaluación en el contexto de esta tendencia de utilizar tecnologías innovadoras para la investigación. Como parte de los resultados, los datos obtenidos permiten seleccionar tanto las variables como las propiedades físicas de la biela y pueden ser utilizados para desarrollar proyectos y estudios de esta naturaleza aplicables en casos de estudio relacionados con la Ingeniería mecánica, mecatrónica, industrial y electrónica. Finalmente, las variables Factor de Seguridad (FS), Von Mises Stress (VM) y YZ Stress, se analizan después de la simulación mediante FEM, proporcionando un rango de valores para su uso en aplicaciones de ingeniería con diferentes técnicas en las que se utilizan bielas, FS [ 0,55, 12,26], VM [1,63, 36,45], YZ [-1,36, 10,13]. En cuanto a los demás resultados presentados en este estudio, el coeficiente de correlación se utiliza como parte estadística con gráficos para evaluar la simulación, la dependencia de variables y parámetros relevantes para el estudio de caso, por lo que se observó una fuerte relación entre las variables; esfuerzo plano, deformación, desplazamiento y el esfuerzo de Von Mises, cuyos valores oscilan entre 0,87 y 0,99, mostrando una fuerte relación entre estas variables y, para las demás, se debe considerar mejorar la relación y aumentar el coeficiente.

ABSTRACT Integrated management is considered the best strategy to mitigate the damage caused by plant-parasitic nematodes. However, there is still limited information regarding some integrated techniques. Thus, this study aimed to assess the effects of genetic management associated with chemical control of Meloidogyne javanica in soybean (Glycine max (L.) Merr.) The experiment was installed in a greenhouse according to an 8×4 factorial design with eight replicates. The first factor was soybean cultivar (HO Juruena IPRO, resistant; Foco IPRO, HO Maracaí IPRO, and CZ 58B28 IPRO, moderately resistant; HO Mamoré IPRO, moderately susceptible; and Extrema IPRO, CZ 48B32 IPRO, and HO Aporé IPRO, susceptible). The second factor consisted of an untreated control and commercial nematicides based on abamectin, thiodicarb+imidacloprid, and fluopyram. Plants were inoculated with 2000 nematode eggs, and nematode and vegetative variables were evaluated at 65 d after inoculation. There was an interaction effect on nematode variables. Furthermore, there was an additive effect of genetic management and chemical control, mainly in resistant cultivars treated with thiodicarb+imidacloprid or fluopyram with controls of up to 69.90% and 96.86%, respectively. The application of fluopyram and the use of ‘HO Juruena IPRO’, ‘Foco IPRO’, or ‘HO Maracaí IPRO’ also contributed to the control of M. javanica. Vegetative variables were studied by analyzing product effects separately, but results were inconclusive.