Worldwide, millions of people suffer from neurological and psychiatric conditions, such as schizophrenia, depression, and neurodegenerative diseases. These conditions are often linked to hyperactivity of monoamine oxidase B (MAO-B) in the brain, and inhibiting this enzyme can reduce oxidative stress, stabilize neurotransmitter levels, and alleviate symptoms. In this context, a pharmacophoric model was created using PharmaGist with 31 hits extracted from BindingDB to enable a pharmacophoric-based search of potential MAO-B inhibitors in ZincPharmer’s chemical space, followed by the building of 10 conformers for each molecule in the software OMEGA, screening for structural and electrostatic similarity to safinamide using ROCS (Rapid overlay of chemical structures) and EON (Electrostatic similarity for lead-hopping), respectively. In addition, the molecular docking with Gold using the score function was performed to rank the ligands with the highest probabilities of affinity to MAO-B and then discriminate those with suitable physical chemical, pharmacokinetic, and toxicological features using the tools QikProp, SwissADME, and DEREK. Four potential ligands with selective MAO-B inhibitor properties were identified, which show promise as future therapeutic agents for MAO-B-related disorders. Worldwide schizophrenia depression diseases MAOB MAO (MAO-B brain stress levels symptoms context 3 pharmacophoricbased based ZincPharmers ZincPharmer s space 1 OMEGA Rapid structures Electrostatic leadhopping, leadhopping lead hopping , lead-hopping) respectively addition pharmacokinetic QikProp SwissADME DEREK identified MAOBrelated related disorders lead-hopping

ABSTRACT Introduction: this study focuses on the need to validate and reliably measure management indicators in the field of public health in Paraguay using psychometric techniques. Objective: the main objective of this study was to develop a valid and reliable instrument to measure public health management indicators in Paraguay considering its psychometric properties. Methodology: this study followed a quantitative approach using a descriptive and propositional observational design. A pilot test was conducted using Likert scales to capture different aspects of public health management indicators. Exploratory and confirmatory factor analyses were performed to validate the construct, and the JASP was used for statistical analysis. The sample included adults in Paraguay who were connected to the public health system in the previous year. Results: the results showed that Aiken's V for all items was higher than 0.7, indicating content validity. The fit indices of the confirmatory factor analysis, such as RMSEA=0.064 and CFI=0.971, demonstrated good construct validity. In addition, the alpha and omega values were higher than 0.9, which guarantees the high reliability of the instrument. Conclusion: these results indicate that the developed instrument is valid and reliable for measuring public health management indicators in Paraguay.

RESUMEN Introducción: la investigación se centra en la necesidad de validar y medir de manera confiable indicadores de gestión en el campo de la salud pública en Paraguay mediante técnicas psicométricas. Objetivo: el objetivo principal de este estudio fue desarrollar un instrumento válido y confiable para medir indicadores de gestión de salud pública en Paraguay considerando sus propiedades psicométricas. Metodología: esta investigación siguió un enfoque cuantitativo con un diseño observacional descriptivo y proposicional. Se realizó una prueba piloto utilizando escalas Likert para capturar diferentes aspectos de los indicadores de gestión de salud pública. Se realizaron análisis factoriales exploratorias y confirmatorias para validar el constructo y para el análisis estadístico se utilizó el programa JASP. La muestra incluyó a adultos de Paraguay que estuvieron relacionados con el sistema público de salud en el año anterior. Resultados: los resultados mostraron que la V de Aiken para todos los ítems fue superior a 0,7, lo que indica validez de contenido. Los índices de ajuste del análisis factorial confirmatorio como RMSEA=0,064 y CFI=0,971 demostraron una buena validez de constructo. Además, los valores alfa y omega fueron superiores a 0,9, lo que garantiza la alta confiabilidad del instrumento. Conclusión: estos resultados permitieron concluir que el instrumento desarrollado es válido y confiable para medir indicadores de gestión de salud pública en Paraguay.

ABSTRACT Potassium (K) and B are important for phloem translocation, reproductive growth, and grain formation. A 2-yr field study was conducted to evaluate the effect of K and B applied through the soil and foliar application on sunflower (Helianthus annuus L.) Experiments included the soil application of K (62 kg ha-1) and B (5 kg ha-1) and foliar spray of K (1%) and B (0.1%). Furthermore, the soil-applied K and B was supplemented with three foliar sprays of either K, B, or both at 45, 60 and 75 d after sowing. The results revealed that K and B fertilization improved the agronomic parameters of sunflower, including plant height, head diameter, achenes per head, achene weight, yield, seed oil contents and oil quality. The soil applied K at 62 kg ha-1 followed by foliar spray of 1% K + 0.1% B at 45, 60 and 75 DAS resulted in production of taller plants (192 and 172 cm), head diameter (23 and 28 cm), achene per head (954 and 1063), 1000 achene weight (68 and 67.58 g), achene yield (2976 and 2621 kg ha-1), biological yield (11363 and 8430 kg ha-1), oil contents (43.37% and 41.87%), and oleic acid (70.33% and 80.83%) over 2 yr of study. Hence it can be concluded that soil application of 62 kg ha-1 K followed by foliar application of 1% K + 0.1% B is the preferable fertilization strategy for sunflower for improved yield, seed oil contents, and oil quality.

Abstract Purpose: To adapt and validate in Sonora the scale to measure Attitudes towards Transgender People in University Students (EATU), which measures the inclusion of trans people in Higher Education Institutions (HEIS). Methodological design: Quantitative, cross-sectional and non-experimental study. 860 participants were selected among three HEIS, with non-probabilistic and intentional sampling. A 4-point Likert-type scale survey was applied that evaluates transinclusive attitudes. Reliability was obtained with Cronbach's alpha and McDonald's omega. For validity, the sample was randomly divided into two; In subsample 1, an Exploratory Factor Analysis (EFA) was carried out and in subsample 2, the model resulting from the EFA was tested using a Structural Equation Model (SEM). Results: The EFA yielded a final solution EATU of 32 items grouped into 3 dimensions called sensitivity, coexistence and cisexist stigma, with values that demonstrate validity and reliability. The SEM generated a model with indices of fitness in a final solution of 17 items and 3 correlated dimensions with acceptable coefficients. Research limitations: The measurement of transinclusion attitudes in a society where it has been documented that such construct is barely being developing, and the failure to collect demographic data on the sample about their religious beliefs. Findings: A measurement instrument on transinclusive attitudes for key social actors interested in promoting the inclusion of trans people, their human rights and substantive equality.

Resumen Objetivo: Adaptar y validar en el contexto sonorense la Escala para medir Actitudes hacia las Personas Transgénero en Estudiantes Universitarios (EATU) que mide la inclusión de personas trans en Instituciones de Educación Superior (IES). Diseño metodológico: Es un estudio cuantitativo, transversal y no experimental. De tres IES, participaron 860 personas seleccionadas con muestreo no probabilístico e intencional. Se aplicó una escala tipo Likert de 4 puntos que evalúa actitudes transincluyentes. La fiabilidad se obtuvo con alfa de Cronbach y omega de McDonald. Para la validez la muestra se dividió al azar en dos; en la submuestra 1 se llevó a cabo un Análisis Factorial Exploratorio (AFE) y en la submuestra 2 se probó el modelo resultante del AFE mediante un Modelo de Ecuaciones Estructurales (MEE). Resultados: El AFE arrojó una solución final de la EATU de 32 ítems agrupados en 3 dimensiones denominadas sensibilidad, convivencia y estigma cisexista, con valores de fiabilidad superiores a .90 y de cargas factoriales superiores a .36. El MEE generó un modelo con índices de bondad de ajuste en una solución final de 17 ítems y 3 dimensiones correlacionadas con coeficientes superiores a .46. Limitaciones de la investigación: La medición de actitudes de transinclusión en una sociedad donde se ha documentado que tal constructo está en desarrollo y el no recabar datos demográficos en la muestra sobre sus creencias religiosas. Hallazgos: Un instrumento de medida sobre actitudes transincluyentes para actores sociales clave interesados en la promoción de la inclusión de las personas trans, sus derechos humanos y la igualdad sustantiva.

Resumen: Este estudio de diseño instrumental analiza las evidencias de validez y confiabilidad del IAMI-R en adolescentes peruanos. Participaron 486 estudiantes de quinto año de secundaria (44.03 % varones y 55.97 % mujeres) de colegios de Chiclayo (65.43 %) y Cajamarca (34.57 %), Perú, con edades entre 15 a 17 años (M= 16.23; DE= .62). La estructura interna fue evaluada mediante análisis factorial confirmatorio (AFC) y la fiabilidad mediante los coeficientes omega y alfa ordinal. Se aplicó AFC con el estimador WLSMV para probar el modelo de ocho factores correlacionados, se hallaron índices de ajuste adecuados: X 2(1052) = 1786.25, p < .001, CFI = .96, TLI = .96, RMSEA (IC 90%) = .04 (.035 - .041) y SRMR = .05. Los índices de confiabilidad oscilaron entre .82 y .91. Se reportaron diferencias significativas en la percepción de autoeficacia para las inteligencias lógico-matemática, cinestésico corporal, interpersonal, intrapersonal y espacial, donde los varones se autovaloran con más capacidad que las mujeres. Se discuten los resultados y alcances del estudio

Resumo: Este estudo de design instrumental analisa as evidências de validade e confiabilidade do IAMI-R em adolescentes peruanos. Participaram 486 alunos do quinto ano da escola secundária (segundo o sistema educativo peruano) (44,03 % homens e 55,97 % mulheres) de colégios de Chiclayo (65,43 %) e Cajamarca (34,57 %), Peru, com idades entre 15 e 17 anos (M = 16,23; DP = 0,62). A estrutura interna foi avaliada por meio de análise fatorial confirmatória (AFC) e a confiabilidade por meio dos coeficientes ômega e alfa ordinal. A AFC foi aplicada com o estimador WLSMV, para avaliar o modelo correlacionado de oito fatores, e foram encontrados índices de ajuste adequados: X 2(1052) = 1786,25, p < 0,001, CFI = 0,96, TLI = 0,96, RMSEA (IC 90%) = 0,04 (0,035 - 0,041) e SRMR = 0,05. Os índices de confiabilidade variaram de 0,82 a 0,91. Foram relatadas diferenças significativas na percepção de autoeficácia para as inteligências lógico-matemática, corporal-cinestésica, interpessoal, intrapessoal e espacial, sendo que os homens se autoavaliaram mais capazes do que as mulheres. Os resultados e alcances do estudo são discutidos

Abstract: This instrumental design study examines the validity and reliability evidence of the IAMI-R in Peruvian adolescents. A total of 486 fifth-year high school students (44.03 % male and 55.97 % female) from schools in Chiclayo (65.43 %) and Cajamarca (34.57 %), Peru, participated in the study. The participants were aged between 15 to 17 years (M = 16.23; SD = 0.62). The internal structure was evaluated using confirmatory factor analysis (CFA), and reliability was assessed through omega and ordinal alpha coefficients. CFA with the WLSMV estimator was applied to test the model of eight correlated factors, revealing adequate fit indices: X²(1052) = 1786.25, p < .001, CFI = .96, TLI = .96, RMSEA (90% CI) = .04 (.035-.041), and SRMR = .05. The reliability indices ranged from .82 to .91. Significant differences were found in the self-efficacy perceptions for logical-mathematical, bodily-kinesthetic, interpersonal, intrapersonal, and spatial intelligences, with males rating themselves as more capable than females. The results and implications of the study are discussed

Resumen Objetivo: recopilar información de factores de riesgo de la enfermedad arterial coronaria en población adulta evidenciados mediante estudios de aleatorización mendeliana. Métodos: de acuerdo con las recomendaciones de la escala para la Evaluación de Artículos de Revisión Narrativa (SANRA), se realizó una revisión desde el usuario de la Universidad Militar Nueva Granada en las bases de datos de PubMed, EMBASE y BIREME. Resultados: se obtuvieron 757 artículos, luego se aplicaron los criterios de inclusión y exclusión, y se eligieron 29 artículos en los que se investiga la asociación de la enfermedad arterial coronaria con la apolipoproteína B, colesterol LDL, triglicéridos, colesterol total, apolipoproteina C3, proteína de transferencia de ésteres de colesterol, HDL, omega 6, lipoproteína (a), obesidad, hemoglobina A1C, diabetes mellitus tipo 2, glucosa en ayunas, inicio del hábito de fumar, presión arterial, hormona paratiroidea sérica, niveles de fosfato sérico, enfermedad del hígado graso no alcohólico, síndrome de ovario poliquístico, globulina fijadora de hormonas sexuales, testosterona, filoquinona circulante, proteína gla de la matriz inactiva, antioxidantes circulantes derivados de la dieta, glicina, homocisteína, ácido úrico, marcadores inflamatorios, hemoglobina, hematocrito y recuento de glóbulos rojos. Conclusión: esta revisión sugiere nuevos estudios con información genética colombiana para respaldar los factores de riesgo aquí presentados, teniendo en cuenta que en ninguno de los estudios evaluados se utilizó información genética latinoamericana, lo cual puede limitar la extrapolación de los resultados.

Summary: Objective: To compile information on risk factors for coronary artery disease in the adult population evidenced by Mendelian randomization studies.. Methods: A search was carried out from the user of the Nueva Granada Military University in the databases of PubMed, EMBASE and BIREME and a narrative review of the literature was carried out in accordance with the recommendations of the scale for the Evaluation of Narrative Review Articles (SANRA). Results: 757 articles were obtained, after the application of inclusion and exclusion criteria, 29 articles were chosen that investigated the association of apolipoprotein B, LDL cholesterol, triglycerides, total cholesterol, apolipoprotein C3, cholesterol ester transfer protein, HDL, omega 6, lipoprotein (a), obesity, hemoglobin A1C, type 2 diabetes mellitus, fasting glucose, smoking initiation, blood pressure, serum parathyroid hormone, serum phosphate levels, non-alcoholic fatty liver disease, polycystic ovary syndrome , sex hormone-binding globulin, testosterone, circulating phylloquinone, inactive matrix protein gla, circulating dietary-derived antioxidants, glycine, homocysteine, uric acid, inflammatory markers, hemoglobin, hematocrit, and red blood cell count, with coronary artery disease. Conclusion: This review suggests new studies with Colombian genetic information to support the risk factors presented here, considering that none of the studies evaluated used Latin American genetic information, which may limit the extrapolation of the results.

Resumen (Objetivo) El objetivo del documento es verificar la estructura factorial de la Escala de Clima Escolar en Ambientes Universitarios (ECEAU) mediante modelos de ecuaciones estructurales (SEM). (Metodología) Se realizó un estudio transversal no experimental con una muestra aleatoria de 381 estudiantes de la Universidad Nacional de Costa Rica, a los que se le aplicó la ECEAU. Se planteó un modelo SEM para verificar la estructura factorial de la escala y un análisis factorial exploratorio (AFE) que brindó la base para proponer un modelo SEM alternativo con una estructura distinta. La confiabilidad de las escalas se determinó mediante el omega de McDonald y los criterios de bondad de ajuste para los modelos SEM fueron el RMSEA, el CFI, el TLI y el GFI. El análisis se efectuó con el software R. (Resultados) La confiabilidad de las escalas en ambos modelos resultaron adecuadas (w >0.70), aunque mejores en el modelo propuesto. El AFE sugirió una estructura diferente para la ECEAU, manteniendo algunas dimensiones de la estructura original y modificando y eliminando otras. Los indicadores de bondad de ajuste, en ambos modelos, fueron casi idénticos con RMSEA=0.02, CFI=0.99, el TLI=0.99 y GFI=0.98, lo que brinda evidencia a favor de las estructuras factoriales planteadas. (Conclusiones) Se verifica la estructura originalmente planteada en la ECEAU y las diferencias en los métodos de estimación y rotación generaron la propuesta de otra estructura factorial, igualmente válida, para medir el constructo clima escolar, en el contexto universitario estudiado y que puede ser aplicado a contextos similares.

Resumo (Objetivo) O objetivo do artigo é verificar a estrutura fatorial da Escala de Clima Escolar em Ambientes Universitários (ECEAU) usando modelagem de equações estruturais (SEM). (Metodologia) Foi realizado um estudo transversal não experimental com uma amostra aleatória de 381 alunos da Universidade Nacional da Costa Rica, aos quais foi aplicada a ECEAU. Uma modelagem SEM foi usada para verificar a estrutura fatorial da escala e uma análise fatorial exploratória (AFE) forneceu a base para a proposta de uma modelagem SEM alternativa com uma estrutura diferente. A confiabilidade das escalas foi determinada pelo ômega de McDonald e os critérios de adequação dos modelos SEM foram RMSEA, CFI, TLI e GFI. A análise foi realizada com o software R. (Resultados) A confiabilidade das escalas em ambos os modelos foi adequada (w >0,70), embora melhor no modelo proposto. A AFE sugeriu uma estrutura diferente para a ECEAU, mantendo algumas dimensões da estrutura original e modificando e eliminando outras. Os indicadores de adequação em ambos os modelos foram quase idênticos, com RMSEA=0,02, CFI=0,99, TLI=0,99 e GFI=0,98, o que fornece evidências a favor das estruturas de fatores propostas. (Conclusões) Confirmou-se a estrutura originalmente proposta no ECEAU e as diferenças nos métodos de estimativa e rotação geraram a proposta de outra estrutura fatorial, igualmente válida, para medir o construto clima escolar no contexto universitário estudado e que pode ser aplicada a contextos semelhantes.

Abstract (Objective) The aim of this paper is to verify the factorial structure of the School Climate Scale in University Environments (ECEAU) through structural equation models (SEM). (Methodology) A non-experimental cross-sectional study was carried out with a random sample of 381 students of the Universidad Nacional de Costa Rica (UNA), to whom the ECEAU was applied. A SEM model was proposed to confirm the factor structure of the scale and an exploratory factor analysis (EFA) was used to provide the basis for an alternative SEM model with a different structure. The reliability of scales was determined using McDonald’s omega, and the goodness of fit indexes used for the SEM models were the RMSEA, the CFI, the TLI and the GFI. The analysis was carried out using R software. (Results) The reliability of the scales in both models was adequate (w>0.70), although the metrics in the proposed model produced better results. The AFE suggested a different structure for the ECEAU, keeping some dimensions of the original structure and modifying and eliminating others. The goodness of fit indexes in both models were almost identical, with RMSEA=0.02, CFI=0.99, TLI=0.99 and GFI=0.98, which provides supporting evidence for the factorial structures proposed. (Conclusions) The original structure of the ECEAU was confirmed, while the differences in the results of the estimation and rotation methods generated another equally valid factorial structure for measuring the school climate construct in this university, and could be applied to other similar contexts.

Abstract Objective: To establish the psychometric properties of the aggression questionnaire (AQ) in a sample of Colombian children and adolescents. Method: The AQ was submitted to the judgment of seven experts in order to verify and adjust the clarity of the items taking into account the characteristics of the Colombian population. Following this analysis and adjustment of items, the instrument was applied to a sample of 892 participants between 10 and 23 years of age. For validity, evidence of internal structure was taken into account through confirmatory factor analysis and evidence based on the relationship with other variables. Results: Confirmatory factor analysis showed two models, one of factorial correlation and the other of second order indicating a model fit. Likewise, internal consistency was calculated by means of the Omega index, which showed precision in the measures for each factor in each of the models. The analysis suggested the elimination of four items. Conclusions: The first-order model was chosen because the empirical evidence shows that it satisfactorily operationalises the theoretical model of aggressive behaviour with which the instrument was constructed, assuming that the four subscales are necessary as a whole, but by themselves are not sufficient to assess aggressive behaviour by means of its items.

Resumen Objetivo: Establecer las propiedades psicométricas del cuestionario de agresión (CA) en una muestra de niños y adolescentes colombianos. Método: El AQ fue sometido al juicio de siete expertos con el fin de verificar y ajustar la claridad de los ítems teniendo en cuenta las características de la población colombiana. Luego de este análisis y ajuste de ítems, se aplicó el instrumento a una muestra de 892 participantes entre 10 y 23 años de edad. Para la validez se tuvo en cuenta la evidencia de la estructura interna a través del análisis factorial confirmatorio y la evidencia basada en la relación con otras variables. Resultados: El análisis factorial confirmatorio mostró dos modelos, uno de correlación factorial y otro de segundo orden indicando un ajuste del modelo. Asimismo, se calculó la consistencia interna mediante el índice Omega, que mostró precisión en las medidas para cada factor en cada uno de los modelos. El análisis sugirió la eliminación de cuatro ítems. Conclusiones: Se eligió el modelo de primer orden porque la evidencia empírica muestra que operacionaliza satisfactoriamente el modelo teórico de conducta agresiva con el que se construyó el instrumento, asumiendo que las cuatro subescalas son necesarias en su conjunto, pero por sí solas no son suficientes para evaluar la conducta agresiva por medio de sus ítems.

Abstract This study focuses on analyzing the psychometric properties of the Internalized Homonegativity Test among homosexual individuals in the department of Nariño (Colombia), aiming to develop a relevant and adapted instrument for gender and sexual orientation studies in the region. It employs a quantitative instrumental cross-sectional design with a sample of 161 participants, including both gay and lesbian individuals from 25 municipalities in Nariño. Participants' ages ranged from 15 to 87 years, selected through convenience sampling using the Snowball method. The Internalized Homonegativity Test, the Homosexual Sexual Orientation Recognition Scale, and a Sociodemographic-Generational Questionnaire were administered. Exploratory and confirmatory factor analyses, correlation and hypothesis testing, and calculations of Cronbach's Alpha and McDonald's Omega were conducted using JASP V 0.17.1 software. The results indicate that the instrument exhibits a unifactorial structure explaining 56.4 % of the common variance in the data and adequate internal consistency, with reliability values ranging from 0.828 to 0.894. These findings support the scale's reliability for measuring internalized homonegativity in the studied context.

Resumen Este estudio se centra en analizar las propiedades psicométricas de la Prueba de Homonegatividad Internalizada en individuos homosexuales del departamento de Nariño (Colombia), con el propósito de desarrollar un instrumento pertinente y adaptado para los estudios sobre género y orientación sexual en la región. Se emplea un diseño transversal instrumental de enfoque cuantitativo, con una muestra de 161 participantes, tanto gais como lesbianas, provenientes de 25 municipios de Nariño. La edad de los participantes abarcó un rango de 15 a 87 años, seleccionados mediante un muestreo no probabilístico por conveniencia tipo Bola de Nieve. Se aplicaron la Prueba de Homonegatividad Internalizada, la Escala de Reconocimiento de la Orientación Sexual Homosexual y un Cuestionario Sociodemográfico-Generacional. Se realizaron análisis factorial exploratorio y confirmatorio, pruebas de correlación y de hipótesis, así como cálculos de Alfa de Cronbach y Omega de McDonald mediante el software JASP V 0.17.1. Los resultados indican que el instrumento muestra una estructura unifactorial que explica el 56.4 % de la varianza común de los datos y una consistencia interna adecuada, con valores de fiabilidad entre 0.828 y 0.894. Estos hallazgos respaldan la fiabilidad de la escala para medir la homonegatividad internalizada en el contexto estudiado.

ABSTRACT Taurine supplementation has shown survival and feeding efficiency in larval fish development. Thus, the present study aims to evaluate the effects of adding taurine to the longfin yellowtail (Seriola rivoliana) diet for 60 days. Fish (n = 270) were distributed in three treatments: T0 without taurine, T1, and T2, supplemented with taurine at 1 and 2%, respectively. Growth performance, blood serum biochemistry, fatty acid, and amino acid profiles in skeletal muscle were evaluated. Notable improvements (P < 0.05) were observed in T1 and T2 in terms of specific growth rate (SGR) and weight gain (WG). Survival rates (SR) did not show significant differences (P > 0.05). In addition, a decrease was observed in intraperitoneal fat (IPF). Still, an increase was observed in blood parameters, including higher total protein (TP) and globulin (GLO) concentration, as well as a reduction in cholesterol (CHO) levels. Changes in fatty acid profiles were also detected in skeletal muscle with an increase in omega-3 fatty acids (EPA and DHA) and elevation in taurine concentration in T2. The results showed that adding 20 g kg-1 of taurine to the diet improved growth, skeletal muscle, and blood serum biochemistry. Therefore, the use of higher taurine concentrations is recommended in future studies to understand fully the extent of the benefits to longfin yellowtail juveniles.

ABSTRACT The general objective was to determine the validity evidence of the flowering scale. The specific objectives were planned to find the evidence of internal structure, criterion and content validity; as well as reliability due to internal consistency. This type of research was applied with an instrumental design; the sample consisted of 520 people, between men and women. The results show acceptable values in the adjustment indices (X22.28, SRMR.038, RMSEA.059, CFI.958, PCFI.684), the convergence and divergence were confirmed by the variables of Satisfaction with Life, Psychological Well-being, Depression, Anxiety and Stress; and McDonald's pro-omega reliability (.796). Because of that, we conclude that this is a valid and reliable one-dimensional instrument of eight items, which can be used in adults from Trujillo.

RESUMEN Se planteó como objetivo general determinar las evidencias de validez de la escala de Florecimiento y como objetivos específicos, hallar las evidencias de estructura interna, validez de criterio y de contenido; así como, la confiabilidad por consistencia interna. El tipo de investigación fue aplicada con un diseño instrumental, la muestra estuvo conformada por un total de 520 personas de ambos sexos. Los resultados muestran valores aceptables en los índices de ajuste (X22.28, SRMR.038, RMSEA.059, CFI.958, PCFI.684), se confirmó la convergencia y divergencia con las variables Satisfacción con la Vida, Bienestar Psicológico, Depresión, Ansiedad y Estrés; y la confiabilidad por omega de McDonald (.796). Se concluye así, con un instrumento válido y confiable unidimensional de ocho ítems, que puede ser utilizado en adultos de la provincia de Trujillo.

Resumo O comportamento alimentar pode exercer uma influência substancial no desenvolvimento da obesidade, uma condição intrinsecamente ligada a um espetro de comorbilidades (e.g., cancro, doenças cardiovasculares, endócrinas). A obesidade é mais prevalente nas mulheres de meia-idade, particularmente durante a menopausa, coincidindo com um aumento da incidência de comportamentos alimentares disfuncionais. Este estudo tem como objetivo identificar a estrutura fatorial e as propriedades psicométricas da versão portuguesa do Three Fator Eating Questionnaire (TFEQ-R21) em mulheres de meia-idade. Um total de 1895 mulheres portuguesas de meia-idade (M=52,22 anos, DP=5,10) preencheram um questionário sociodemográfico e o TFEQ-R21, composto por 21 itens, distribuídos por três dimensões (restrição cognitiva, descontrolo alimentar e alimentação emocional). Foram realizadas análises descritivas, validade de construto, de critério, e fiabilidade, através do R-Lavaan. O modelo de estrutura de três fatores apresentou um bom ajustamento (Comparative Fit Index=0,97; Tucker-Lewis Index=0,97; Root mean square error of approximation= 0,08 (p<0,001); Standardized root mean square residual=0,07). O TFEQ-R21 apresenta evidências de validade convergente (variância extraída da média: 0,41<VEM<0,80) e fiabilidade (α de Cronbach: 0,82<α<0,96, e ómega de McDonald: 0,66<ω<0,92). O TFEQ-R21 apresentou evidências de validade e fiabilidade com invariância entre mulheres com e sem obesidade, na avaliação do comportamento alimentar em mulheres de meia-idade. É um instrumento útil no domínio das intervenções de gestão de peso, facilitando a identificação e a atenuação de comportamentos alimentares disfuncionais, especialmente durante esta fase da vida.

Abstract Eating behaviour can exert a substantial influence on the development of obesity, a condition intricately linked with a spectrum of comorbidities (e.g., cancer, cardiovascular diseases, endocrine disorders). Obesity is more prevalent among middle-aged women, particularly during menopause, coinciding with an increase in the incidence of disordered eating behaviours. This study aims to identify the factor structure and psychometric properties of the Portuguese version of the Three Factor Eating Questionnaire (TFEQ-R21) in middle-aged women. A total of 1895 middle-aged Portuguese women (M=52.22 years, SD=5.10) completed a sociodemographic questionnaire alongside the TFEQ-R21, comprising 21 items distributed across three dimensions (cognitive restraint, uncontrolled eating, and emotional eating). Descriptive analyses, construct and criterion validities, and reliability were performed using the R-Lavaan. The three-factor structure model presented a good fit (Comparative Fit Index=0.97; Tucker-Lewis Index=0.97; Root mean square error of approximation=0.08 (p<.001); Standardized root mean square residual=0.07). The TFEQ-R21 attests to its convergent validity (average variance extracted: 0.41<AVE<0.80) and reliability (Cronbach´s α: 0.82<α<0.96, and McDonald´s omega: 0.66<ω<0.92). The TFEQ-R21 tool has shown evidence of validity and reliability, displaying invariance between obese and normative women when assessing eating behaviour among middle-aged women. It offers valuable utility within the domain of weight management interventions, facilitating the identification and mitigation of dysfunctional eating behaviours, especially during this life stage.

Resumen La orientación vocacional y profesional de los estudiantes de educación superior es esencial para garantizar el éxito en el aprendizaje y la práctica profesional. El objetivo de esta investigación es comparar las carreras autodeclaradas y los resultados del test de orientación vocacional y profesional según los tipos de orientación vocacional. Utilizando investigación descriptiva, documental y de campo con un enfoque mixto, exploramos el test de orientación vocacional de 3.692 estudiantes de 13 colegios públicos de la ciudad de Ibarra en Ecuador. La prueba consistió en 98 ítems dicotómicos que identificaron intereses y aptitudes vocacionales mediante un cuestionario computarizado en Kobotoolbox. La validez del instrumento se evaluó mediante el Alfa de Cronbach y la fiabilidad se estimó mediante los coeficientes Omega de McDonald. Se utilizó la prueba de Chi-cuadrado para comparar las carreras autoinformadas y los resultados de la prueba CHASIDE por orientación vocacional y profesional de los estudiantes mediante el software R-studio. Los resultados mostraron diferencias significativas entre las carreras autoinformadas por los estudiantes y el CHASIDE. De hecho, la correspondencia entre ambas mostró valores inferiores al 50% ya que un miembro de la familia realizaba principalmente procesos de orientación vocacional, y la orientación profesional debía estar más presente. Los resultados sugieren la importancia de la orientación vocacional realizada por un profesional antes de ingresar a las instituciones de educación superior para minimizar el riesgo de deserción entre los estudiantes después de elegir erróneamente una carrera.

Abstract Vocational and professional guidance for higher education students is essential to ensure success in learning and professional practice. This research aims to compare self-reported careers and vocational and professional orientation test results by types of vocational guidance. Using descriptive, documentary, and field research with a mixed approach, we explore the vocational orientation test of 3,692 students in 13 public schools in the city of Ibarra in Ecuador. The test consisted of 98 dichotomous items identifying vocational interests and aptitudes using a computer-based questionnaire in Kobotoolbox. The instrument's validity was evaluated using Cronbach's Alpha, and reliability was estimated using McDonald's Omega coefficients. The Chi-square test was used to compare self-reported careers and the CHASIDE test results by vocational and professional guidance of the students using the R-studio software. Results showed significant differences between students' self-reported careers and the CHASIDE. Indeed, the correspondence between the two showed values lower than 50% since a family member mainly did vocational guidance processes, and professional guidance needed to be more present. Results suggest the importance of vocational guidance done by a professional before entering higher education institutions to minimize the risk of dropouts among students after mistakenly choosing a career.

RESUMEN Introducción: durante las últimas dos décadas, el concepto de capital social se ha utilizado con creciente frecuencia en las ciencias de la salud debido a las relaciones directas e indirectas entre el capital social y la salud física y mental de las poblaciones. Por tanto, es necesario construir un instrumento para cuantificar este concepto con seguridad y confiabilidad. Objetivo: analizar la consistencia interna y dimensionalidad de una escala de siete ítems para medir el capital social en adultos de la población general de Colombia. Metodología: se realizó un estudio de validación en línea, que incluyó una muestra de 700 adultos de entre 18 y 76 años, el 68 % eran mujeres. Los participantes completaron una escala de siete ítems llamada Escala de Capital Social Cognitivo (ECSC). El alfa de Cronbach y el omega de McDonald se calcularon para probar la consistencia interna. Se realizaron análisis factoriales exploratorios y confirmatorios para explorar la dimensionalidad de la ECSC. Resultados: la ECSC presentó una consistencia interna baja (alfa de Cronbach de 0,56 y omega de McDonald de 0,59) y pobre dimensionalidad. Seguidamente, se probó una versión de cinco ítems (ECSC-5). La ECSC-5 mostró una alta consistencia interna (alfa de Cronbach de 0,79 y omega de McDonald de 0,80) y una estructura unidimensional con indicadores de bondad de ajuste aceptables. Discusión: la ECSC-5 presenta alta consistencia interna y una estructura unidimensional para medir el capital cognitivo social en adultos colombianos. Se recomienda la ECSC-5 para la medición del capital social en la población general colombiana. Futuras investigaciones deben corroborar estos hallazgos en aplicaciones de lápiz y papel y explorar otros indicadores de confiabilidad y validez.

ABSTRACT Introduction: During the last two decades, the concept of social capital has been used increasingly frequently in health sciences due to the direct and indirect relationships between social capital and populations' physical and mental health. Therefore, it is necessary to build an instrument to quantify this concept confidently and reliably. Objective: The study aimed to internal consistency and dimensionality of a seven-item scale to measure social capital in Colombia's general population of adults. Methods: An online validation study included a sample of 700 adults aged between 18 and 76 years; 68% were females. Participants completed a seven-item scale called the Cognitive Social Capital Scale (CSCS). Cronbach's alpha and McDonald's omega were computed to test internal consistency. The authors explore the internal consistency and dimensionality of the CSCS. Results: The CSCS presented a low internal consistency (Cronbach's alpha of 0.56 and McDonald's omega of 0.59) and poor dimensionality. Then, the researchers tested a five-item version (CSCS-5). The CSCS-5 showed high internal consistency (Cronbach's alpha of 0.79 and McDonald's omega of 0.80) and a one-dimension structure with acceptable goodness-of-fit indicators. Discussion: The CSCS-5 presents high internal consistency and a one-dimensional structure to measure cognitive capital social in the Colombian sample. Authors can recommend measuring social capital in the general Colombian population. Further research should corroborate this pencil and paper application findings and explore other reliability and validity indicators.