Diaporthe phaseolorum, an endophyte isolated from Combretum lanceolatum, has exhibited diverse biological activities including antimicrobial, leishmanicidal, antitumoral, and herbicidal properties. Regardless of these activities, there remains limited research on its chemical constituents. Therefore, this study aimed to investigate the metabolome of D. phaseolorum employing mass spectrometry data dereplication through molecular networking and MolNetEnhancer tools. Twenty two molecular families were annotated, including prenol lipids, benzenoids, organoheterocyclic compounds, and nucleosides. Among the 41 nodes annotated, 36 metabolites were confirmed via spectral references, including alismol, farnesol, linoleic acid, tyramine, N-acetyl-tyramine, 5-methoxy-1H-indole-3-carbaldehyde, 6-pentyl-2H-pyran-2-one, and adenosine. Further node annotation was achieved through MolNetEnhancer, resulting in the classification of an additional 68 nodes into various molecular families. Consequently, this study represents a significant contribution to the identification of the D. phaseolorum metabolome, highlighting its secondary metabolites and providing valuable chemical insights to elucidate its demonstrated biological activities. lanceolatum antimicrobial leishmanicidal antitumoral properties constituents Therefore D tools annotated lipids benzenoids compounds nucleosides 4 3 references alismol farnesol acid tyramine Nacetyltyramine, Nacetyltyramine N acetyl N-acetyl-tyramine 5methoxy1Hindole3carbaldehyde, 5methoxy1Hindole3carbaldehyde methoxyHindolecarbaldehyde 5 methoxy 1H indole carbaldehyde, carbaldehyde H 5-methoxy-1H-indole-3-carbaldehyde 6pentyl2Hpyran2one, 6pentyl2Hpyran2one pentylHpyranone 6 pentyl 2H pyran 2 one, one 6-pentyl-2H-pyran-2-one adenosine Consequently Hindole Hpyran

ABSTRACT: We described the first case of rhinofacial pythiosis with dissemination in an adult horse in Uruguay. The affected horse presented a partially circumscribed mass measuring 30 x 23 x 9 cm affecting the right side of the face with involvement of cutaneous, subcutaneous, and muscular tissues, the right nasal cavity, and adjacent structures. At postmortem examination, the main lesions were “kunkers” characterized by pyogranulomatous and eosinophilic dermatitis, Splendore-Hoeppli reaction and numerous intralesional hyphae immunolabeling with polyclonal anti-Pythium insidiosum antibody. Similar lesions were observed in the lung and submandibular lymph nodes. The diagnosis was made by the characteristic histological lesions and the strong immunolabelling by anti-P. insidiosum antibody. ABSTRACT Uruguay 3 2 cutaneous subcutaneous tissues cavity structures examination kunkers “kunkers dermatitis SplendoreHoeppli Splendore Hoeppli antiPythium anti Pythium antibody nodes antiP. antiP P. P anti-P

RESUMO: Descreve-se o primeiro caso de pitiose rinofacial com disseminação em um equino adulto no Uruguai. O animal apresentava uma massa parcialmente circunscrita medindo 30 x 23 x 9 cm acometendo o lado direito da face e com envolvimento dos tecidos cutâneo, subcutâneo e muscular, cavidade nasal direita e estruturas adjacentes. Os principais achados patológicos incluem a formação de kunkers microscopicamente caracterizados por dermatite piogranulomatosa e eosinofilica, reação de Splendore-Hoeppli, e numerosas hifas intralesionais imunomarcadas com anticorpo policlonal anti-Pythium insidiosum. Lesões semelhantes foram observadas no pulmão e nos linfonodos submandibulares. O diagnóstico foi baseado nas lesões histológicas características e imunomarcação com anticorpo anti-P. insidiosum. RESUMO Descrevese Descreve se Uruguai 3 2 cutâneo muscular adjacentes eosinofilica SplendoreHoeppli, SplendoreHoeppli Splendore Hoeppli, Hoeppli Splendore-Hoeppli antiPythium anti Pythium insidiosum submandibulares antiP. antiP P. P anti-P

Autonomous electric vehicles use camera sensors for vision-based steering control and detecting both roads and objects. In this study, road and object detection are combined, utilizing the YOLOv8x-seg model trained for 200 epochs, achieving the lowest segmentation loss at 0.53182. Simulation tests demonstrate accurate road and object detection, effective object distance measurement, and real-time road identification for steering control, successfully keeping the vehicle on track with an average object distance measurement error of 2.245 m. Route planning for autonomous vehicles is crucial, and the A-Star algorithm is employed to find the optimal route. In real-time tests, when an obstacle is placed between nodes 6 and 7, the A-Star algorithm can reroute from the original path (5, 6, 7, 27, and 28) to a new path (5, 6, 9, 27, and 28). This study demonstrates the vital role of sensor fusion in autonomous vehicles by integrating various sensors. This study focuses on sensor fusion for object-road detection and path planning using the A* algorithm. Real-time tests in two different scenarios demonstrate the successful integration of sensor fusion, enabling the vehicle to follow planned routes. However, some route nodes remain unreachable, requiring occasional driver intervention. These results demonstrate the feasibility of sensor fusion with diverse tasks in third-level autonomous vehicles.

Objective: To describe morbidity and mortality associated with colorectal prostheses (CP) and identify factors associated with their complications during the 2007 to 2022 at INDISA Clinic. Material and Method: Retrospective cross-sectional study based on clinical registry. Results: 49 CPs were installed with 100% clearing success. 87.8% in left colon. The main etiology was malignant 91.8% and 85.7% were primary colorectal. 34 were installed with palliative intention, 12 as a bridge to elective surgery (BTS) and 3 for benign pathology. There were 13 (26.5%) patients with adverse effects (7 strictures, 4 perforations and 2 migrations). Associated mortality was 4.1% (2 patients). The complicated group was younger, with more advanced oncological stages and rectosigmoid stenosis (p < 0.005). Those under 50 years of age had 5 times higher risk of some complication (OR = 5.0; 95% CI: 1.09-23.0; p = 0.039). Discussion: The use of CPs has low short-term morbidity and mortality. Its main use is as palliative treatment or BTS in malignant colorectal obstruction. It's a high clearance rate. It is associated with less morbidity than emergency surgery, a lower ostomy rate, and a higher lymph node harvest. Installation as a bridge is also associated with a higher rate of primary anastomosis. Our group showed a higher complication rate in those with advanced and younger tumors. Conclusion: The use of CPs is safe, with low morbidity and mortality. The main indication is in obstructive colorectal neoplasia as palliative treatment. Young patients and advanced colorectal tumors with peritumoral nodes have a higher risk of complications.

Resumen Objetivo: Describir morbimortalidad asociada al uso de prótesis colorrectales (PC) e identificar factores asociados a sus complicaciones durante los años 2007 a 2022 en Clínica INDISA. Material y Método: Estudio transversal retrospectivo basado en registro clínico. Resultados: Se instalaron 49 PC con un 100% de éxito de desobstrucción. El 87,8% en colon izquierdo. La etiología principal fue la patología maligna 91,8% y el 85,7% de ellos fueron primarios colorrectales. Se instalaron 34 como tratamiento paliativo (TP), 12 como puente a cirugía electiva (PCE) y 3 por patología benigna. La tasa de complicaciones fue de 26,5% (7 estenosis, 4 perforaciones y 2 migraciones). La mortalidad asociada fue de 4,1% (2 pacientes). El grupo de complicados fue más joven, con etapas oncológicas más avanzadas y con estenosis en rectosigmoides(p < 0,005). Los menores de 50 años tuvieron 5 veces más riesgo de alguna complicación (OR = 5,0;IC95%:1,09-23,0; p = 0,039). Discusión: El uso de PC tiene baja morbimortalidad. Su uso principal es como TP o PCE en obstrucción colorrectal maligna, con alta tasa de desobstrucción. Está asociado con menor morbilidad que la cirugía de urgencia, menor tasa de ostomía y mayor cosecha ganglionar. La instalación como puente se asocia además a mayor tasa de anastomosis primaria. Nuestra serie mostró mayor tasa de complicación en aquellos con tumores avanzados y más jóvenes. Conclusión: El uso de PC es seguro y con baja morbimortalidad. La principal indicación es en neoplasia colorrectal obstructiva como TP. Tienen mayor riesgo de complicación los pacientes jóvenes y los tumores colorrectales avanzados con ganglios peri tumorales.

Resumen El presente artículo interroga la relación entre justicia y castigo desde los feminismos antipunitivistas en el escenario de una creciente agenda de seguridad. Nos proponemos poner en tensión el reconocimiento punitivo como modo de hacer visibles las diversas violencias de género en los movimientos feministas chilenos de los últimos años. Para ello analizamos la problemática del “espacio seguro” como lugar libre de conflicto; la experiencia de victimización como modo de subjetivación/identificación feminista; y analizamos cómo las agendas de seguridad y justicia se tradujeron en los fallidos procesos constituyentes recientes ocurridos en Chile, sobre todo en el tránsito de una propuesta de Constitución feminista y plurinacional a una criminalizadora y securitista.

Abstract This article interrogates the relationship between justice and punishment from antipunitivist feminisms in the scenario of a growing security agenda. We propose to put in tension the punitive recognition as a way of making visible the diverse gender violence in the Chilean feminist movements of the last years. To this end, we analyse the problematic of the “safe space” as a place free of conflict, the experience of victimization as a mode of feminist subjectivation/identification; and we analyse how the security and justice agendas were translated into the recent unsuccessful constituent processes in Chile, especially in the transition from a feminist and plurinational Constitution proposal to a criminalizing and securitizing one.

Abstract Network theory techniques have recently contributed to the analysis of electrical power systems, enabling faster computational solutions. Taking advantage of the topological information of a network, it becomes possible to characterize its elements both locally (individual network components) and globally (interactions and behavior of the components). Identifying the crucial elements within an electrical system involves classifying each component based on its interaction with the entire network, considering, possibly, various operating conditions. Current network centrality measures predominantly focus on nodes, which represent connection buses in the system, to quantify the significance of individual elements. In this study, we employ the linegraph technique to transform links into nodes. Subsequently, we calculate and categorize the links (representing lines and transformers) of different electrical networks found in the literature using three centrality measures. Moreover, our methodology allows for the aggregation or combination of the indices from each measure, leading to a unified classification based on the importance of links in the considered electrical power systems. Analyzing diverse networks reveals a consistent empirical distribution of centrality indices, resulting in similar classifications of significant elements regardless of network size.

Resumen El análisis de sistemas eléctricos de potencia se ha apoyado, recientemente, en la aplicación de técnicas de la teoría de redes, con la finalidad de obtener soluciones computacionalmente más rápidas. A partir de la información topológica de una red, es posible definir características desde lo local (elementos de la red) hasta lo global (comportamiento e interacción de los elementos). La identificación de elementos importantes de un sistema eléctrico, consiste en clasificar cada uno de los elementos desde su interacción con toda la red, y, posiblemente, tomando en cuenta diversas condiciones de operación del sistema. Las medidas de centralidad en redes, que permiten asignar importancia cuantitativa a los elementos de un sistema, están definidas en su mayoría para los nodos (representan buses de conexión) de las mismas. En este trabajo, a partir de la transformación de enlaces a nodos, según la técnica linegraph, se calculan y clasifican los enlaces (representan líneas y transformadores) de diversas redes eléctricas de la literatura, de acuerdo con tres medidas de centralidad. Adicionalmente, el procedimiento presentado permite agregar o combinar los índices de cada medida, y obtener una única clasificación según su importancia para los enlaces de los sistemas eléctricos de potencia considerados. La diversidad de redes analizadas permite concluir que la distribución empírica de los índices de centralidad es similar, y origina una clasificación de elementos importantes semejantes, independiente de la dimensión de la red.

Resumo As relações e os vínculos territoriais são fundamentais para os estudos em Geografia. Nos últimos anos, eles têm passado por uma evolução significativa e não são alheios às investigações sobre a atividade turística, uma vez que os fluxos gerados são responsáveis pela dinâmica territorial. O objetivo principal deste trabalho é revelar as interações espaciais que surgem a partir de uma rota turística internacional, onde seus recursos valorizam o patrimônio das missões jesuítico-guaranis localizadas em três países: Paraguai, Argentina e Brasil. A metodologia empregada combina técnicas qualitativas e quantitativas, utilizando o software de análise de redes Gephi e dos Sistemas de Informação Geográfica (SIG). Por meio da cartografia, destacam-se as características e propriedades dos nós e dos vínculos estabelecidos entre os povos missionários nos quais se registra uma atividade turística preponderante. Além disso, é integrado o conceito de fricção do espaço, o qual funciona para explicar, com mais detalhes, cada uma das relações e vínculos estabelecidos.

Abstract Relationships and territorial links are fundamental to Geography studies. In recent years, these aspects have undergone significant evolution. Besides, the study of tourism activity is not indifferent since the flows generated in places of tourism interests are those that give rise to territorial dynamics. The main objective of this study is to reveal the spatial interactions stemming from an internationally renowned tourist route, with a very particular niche of its resources, which focus on the heritage of the Jesuit-Guarani missions located in three countries: Paraguay, Argentina, and Brazil. The methodology used integrates the use of qualitative and quantitative techniques. These techniques are combined with “Gephi,” a network analysis software, and “Geographic Information Systems” (GIS). With the aid of cartography, the characteristics and properties of the nodes and links established among the “pueblos misionales” in which the primary tourist activities take place are displayed. Additionally, the concept of “friction of space” is incorporated to explain, in more detail, each of the relationships and links established.

Resumen Las relaciones y los vínculos territoriales son fundamentales para los estudios en Geografía. En los últimos años, estos han tenido una evolución significativa y para el estudio de la actividad turística no resultan ajenos, pues los flujos que se generan son los que dan origen a una dinámica territorial. El objetivo central de este trabajo es revelar las interacciones espaciales que se originan a partir de una ruta turística internacional, donde sus recursos ponen en valor el patrimonio de las misiones jesuítico-guaraníes localizadas en tres países: Paraguay, Argentina y Brasil. La metodología utilizada se asocia con el uso de técnicas cualitativas y cuantitativas que se conjuntan con el uso del software de análisis de redes Gephi y de los Sistemas de Información Geográfica (SIG) en el que, a través de la cartografía, se muestran las características y propiedades de los nodos y los vínculos que se establecen entre los pueblos misionales en los que se registra una actividad turística preponderante. Asimismo, se integra el concepto de fricción del espacio que funciona para explicar, con más detalle, cada una de las relaciones y vínculos establecidos.

Abstract Introduction. The amount of usable water is currently limited due to the deterioration of its sources and indiscriminate use. An alternative to this problem is producing under green houses, where it is possible to obtain better water use efficiency (WUE) by reducing crop evapotranspiration (ETc) without compromising its productive potential. Objective. To evaluate the effect of 3 levels of volumetric moisture content depletion in coir on the vegetative-generative behavior of hydroponic tomato and sweet pepper produced under greenhouse cultivation. Materials and methods. The study was conducted during August to December 2020 and January 2021, at Estación Experimental Agrícola Fabio Baudrit Moreno, Alajuela, Costa Rica. Three treatments were applied: 11, 22 and 32% of water depletion in the substrate. Morphophysiological and reproductive parameters such as: the leaf area (AF), the number of leaves (NH), width (AH) and length of the leaf (LH), the length (LT) and the diameter of the stem (DT), the number of nodes (NN), dry matter (DM), stomatal conductance (gs), crop evapotranspiration (ETc), water use efficiency (WUE), the total yield (Rt), the commercial (Rc) of first (F1), second (F2) and third (F3) and waste fruits (Fd) were evaluated. Results. In the tomato treatments (TT) there was no effect on NH, LT, LH and NN; on the other hand, differences were reported in AH, DT and in MS, with treatment TT11 obtaining the higher values. The sweet pepper (TC), the treatment TC11 was statistically superior to the other treatments in number (NH), width (AH) and length (LH) of the leaf, in number of nodes (NN), production of fresh (MF) and dry matter (MS) and in diameter of the stem (DT), while there were no differences between treatments in stem length (LT). There were no differences in ETc and Rt, for both crops, but there was a difference in the commercial yield once it was divided by quality of fruit, TT11 presented the highest production of first and second fruit quality, while treatment TC11 presented the highest production of first, second and third fruit quality. For both crops, there were significant differences between treatments in terms of stomatal conductance. TT11 and TC11 treatments obtained the highest value of EUA with 37.32 kg.m-3 and 21.46 kg.m-3, respectively. Conclusion. In both crops, treatments with 11 and 22% water depletion showed an adequate balance between vegetative and productive growth, which was reflected in greater production of better quality commercial fruits, less waste and greater WUE.

Resumen Introducción. El uso de agua dulce en agricultura se encuentra limitado debido al deterioro de sus fuentes y su uso indiscriminado. El riego deficitario en agricultura protegida es una alternativa para mejorar la eficiencia en el uso del agua, a través de la reducción de la evapotranspiración del cultivo, sin comprometer su potencial productivo. Objetivo. Evaluar el efecto de 3 niveles de agotamiento del contenido de humedad volumétrica en un sustrato de fibra de coco, sobre el comportamiento vegetativo-generativo de los cultivos de tomate y chile dulce hidropónicos en invernadero. Materiales y métodos. El estudio se realizó en la Estación Experimental Agrícola Fabio Baudrit Moreno, Alajuela, Costa Rica. En ambos cultivos se aplicaron 3 tratamientos con 11, 22 y 32% de agotamiento hídrico en el sustrato, en un diseño experimental en bloques completos al azar. Se evaluaron parámetros morfofisiológicos y productivos tales como área foliar (AF), número de hojas (NH), ancho (AH) y longitud de hoja (LH), longitud (LT) y diámetro del tallo (DT), número de nudos (NN), materia seca (MS), conductancia estomática (gs), evapotranspiración del cultivo (ETc), eficiencia de uso de agua (EUA), rendimiento de fruto comercial (Rc) de primera (F1), segunda (F2) y tercera (F3), fruto de desecho (Fd) y rendimiento total (Rt). Resultados. En los tratamientos en tomate (TT) no hubo efecto sobre el NH, LH, LT y NN; mientras que con TT11 se obtuvieron valores superiores en AH, DT y MS. En chile dulce (TC), el TC11 obtuvo mayor NH, AH, LH, NN, DT y MS que los demás tratamientos; mientras que no hubo diferencias entre tratamientos en LT. En ambos cultivos, no hubo efecto sobre la ETc y el Rt, sin embargo, con 11% de agotamiento se obtuvo mayor producción comercial de F1 y F2 por lo que consecuentemente hubo mayor EUA con 37,32 kg.m-3 y 21,46 kg.m-3, respectivamente. Para ambos cultivos, la gs fue diferente entre tratamientos. Conclusión. En ambos cultivos, los tratamientos con 11 y 22% de agotamiento hídrico evidenciaron un adecuado balance entre crecimiento vegetativo y productivo, que se reflejó en mayor producción de frutos comerciales de mejor calidad, menos desecho y mayor EUA.

Abstract The objective of this article is to analyze the transformations in the legal-social discourses around incest, emanating from liberal reformism and the legal transition during the second half of the 19th century, in Michoacán. We start from the fact that the enactment of the Civil Marriage Act (1859) upended the legal systems by reducing the fields in which incest was committed. From that moment on, the lawsuits began to move away from the spiritual terrain, to have only legal repercussions of a criminal nature. Through the methodology of discourse analysis and having as main sources judicial records, legislation and literature of the time, the changes that occurred in the sixties in the justice delivery system, the reduction of incest files and the generation of new discursive nodes are enunciated, all of which outlines modifications in the representations of said crime.

Resumen El objetivo del artículo es analizar las transformaciones en los discursos jurídico-sociales en torno al incesto, emanados del reformismo liberal y la transición jurídica durante la segunda mitad del siglo XIX, en Michoacán. Partimos del hecho de que la promulgación de la Ley de Matrimonio Civil (1859) trastocó los ordenamientos legales al reducir los campos en que se cometía incesto. A partir de ese momento, las demandas judiciales comenzaron a alejarse del terreno espiritual, para tener únicamente repercusiones legales de orden penal. Mediante la metodología del análisis del discurso y teniendo como fuentes principales expedientes judiciales, legislación y literatura de la época, se enuncian los cambios ocurridos en los años sesenta en el sistema de impartición de justicia, la reducción de expedientes de incesto y la generación de nuevos nodos discursivos, lo cual bosqueja modificaciones en las representaciones de dicho delito.

ABSTRACT Introduction: The superiority of the functional results of robot-assisted radical prostatectomyis still controversial. Despite this, it is known that minimally invasive surgery obtains better results when analyzing blood loss, blood transfusion and length of stay, for example. Several studies have analyzed the impact of the resident physician's involvement on the results of urological surgeries. The simple learning curve for robot-assisted radical prostate surgery is estimated to be around 10 to 12 cases. Learning curve data for robotic surgeons is heterogeneous, making it difficult to analyze. Rare studies compare the results of a radical prostatectomy of an inexperienced surgeon starting his training in open surgery, with the results of the same surgeon, a few years later, starting training in robotic surgery. Objective: to analyze the results of open radical prostatectomy surgeries (ORP) performed by urology residents, comparing them to the results of robot-assisted radical prostatectomy (RARP), performed by these same surgeons, after completing their training in urology. Materials and methods: a retrospective analysis of the cases of only 3 surgeons was performed. 50 patients underwent ORP (group A). The surgeons who operated on the ORP patients were in the 3rd and final year of the urology residency program and beginners in ORP surgery, but with at least 4 years of experience in open surgery. The same surgeons, already trained urologists, began their training in robotic surgery and performed 56 RARP surgeries (group B). For the comparative analysis, data were collected on age, number of lymph nodes removed, surgery time, hospitalization time, drain volume, drain permanence time, indwelling bladdercateter (IBC) permanence time, positive surgical margin, biochemical recurrence, risk classification (ISUP), intra and postoperative complications, urinary incontinence (UI) and erectile dysfunction (ED). The console used was the Da Vinci Si, from Intuitive®. For statistical analysis, the Shapiro-Wilk test verified that the data did not follow normality, the Levene test guaranteed homogeneity, and the Mann-Whitney test performed the comparative analysis of the quantitative data. For the analysis of qualitative data, the Chi-square test was used for nominal variables and the Mann-Whitney U test for ordinal variables. Additionally, the Friedman test analyzed whether there was an improvement in the perception of UI or ED over the months, for each group individually (without comparing them), and the post-hoc Durbin-Conover test, for the results with statistically significant difference. We used a p-value < 0.05, and the Jamovi® program (Version 2.0). Results: there was no statistically significant difference between the groups for age, number of lymph nodes removed, positive surgical margin, biochemical recurrence, risk classification and urinary incontinence. Additionally, we observed that the surgical time was longer in group B. On the other hand, the length of stay, drain volume, drain time, IBC time, complication rate and levels of erectile dysfunction in the third and sixth months were higher in group A, when compared to group B. We also observed that there was no evolutionary improvement in ED over the months in both groups, and that there was a perception of improvement in UI from the 1st to the 3rd month in group A, and from the 1st to the 6th month, and from the 3rd to the 12th month, in group B. Conclusion: the learning curve of RARP is equivalent to the curve of ORP. In general, the results for the robotic group were better, however, the functional results were similar between the groups, with a slight tendency of advantage for the robotic arm. Introduction robotassisted robot assisted controversial this loss stay example physicians physician s 1 heterogeneous later Objective (ORP residents RARP, , (RARP) methods 5 A. A . A) rd urologists B B) age removed volume (IBC margin recurrence ISUP, ISUP (ISUP) complications (UI ED. (ED) Si Intuitive Intuitive® ShapiroWilk Shapiro Wilk normality homogeneity MannWhitney Mann Whitney Chisquare Chi square Additionally without them, them) posthoc post hoc DurbinConover Durbin Conover pvalue p value 005 0 05 0.05 Jamovi Version 2.0. 20 2.0 2 2.0) Results hand st th Conclusion general however arm (RARP (ISUP (ED 00 0.0 2. 0.

Resumen Introducción: Este artículo de carácter reflexivo busca formular una matriz teórica de abordaje de los procesos colectivos que permita recuperar el conocimiento, la reflexión, la articulación de las vivencias y saberes esenciales para producir -o conservar- condiciones para la reproducción de la vida. Objetivo: Para dar cuenta de los objetivos, se reflexiona sobre los procesos iniciados en ollas populares y merenderos vecinales, como respuesta a la inseguridad alimentaria acentuada por la pandemia en el Departamento de Maldonado, Uruguay entre 2020 y 2021. Estos procesos deben ser observados en el contexto de políticas públicas implementadas a nivel nacional y departamental, con enfoques y asignaciones presupuestales deficitarias. Método y técnica: Para ello, se optó por un encuadre metodológico de análisis, reflexión y sistematización de información secundaria de diversos artículos e información actualizada al respecto. Resultados: Algunos resultados del artículo refieren a la construcción de un marco referencial que permitió ilustrar vacíos y nodos teóricos que posibilitan mecanismos de reflexividad en relación con las «nuevas necesidades», sentidos y significaciones de las comunidades y organizaciones de la sociedad civil enfocadas a la seguridad alimentaria en el Departamento de Maldonado. Conclusiones: Este abordaje resulta estratégico para el análisis de las prácticas que propendan al fortalecimiento de derechos, la solidaridad, el cuidado comunitario y las potencialidades de construcción de «lo común», sus tensiones, contradicciones y desafíos. En este sentido, resulta una aproximación pertinente para dar cuenta de las contingencias y dinamismo que posee el objeto de estudio desde un punto de vista experiencial.

Abstract Introduction: This reflective article seeks to formulate a theoretical matrix to approach collective processes that allows recovering knowledge, reflection, and the articulation of experiences and essential knowledge to produce -or preserve- conditions for the reproduction of life. Objective: It reflects on the processes initiated in popular pots and merenders as a response to food insecurity, accentuated by the pandemic and the mitigation measures that were initiatives of neighbors or groups of neighbors implemented in the Department of Maldonado, Uruguay, between 2020 and 2021. These processes must be observed in the context of public policies implemented at the national and departmental levels, with deficit apprhes and budgy otros locations. Method and technique: The methodological framework of analysis, reflection and systematization of secondary information was chosen, taking into account various articles and updated information in this regard. Results: Some of the results of the article refer to the construction of a referential framework that made it possible to illustrate gaps and theoretical nodes that enable mechanisms of reflexivity in relation to the «new needs», senses and meanings of communities and civil society organizations focused on food security in the Department of Maldonado. Conclusions: This approach is strategic for the analysis of practices aimed at strengthening rights, solidarity, community care and the potential of building «the common«, its tensions, contradictions and challenges. In this sense, it is a pertinent approach to account for the contingencies and dynamism of the object of study from an experiential point of view.

Resumen: El fenómeno de la okupación urbana comprende experiencias sociales de apropiación y utilización de inmuebles abandonados. A su vez, los Centros Culturales Okupa (CCO) constituyen formas de okupación urbana articuladas en torno a prácticas culturales y artísticas. A partir del análisis de las dimensiones materiales y socio-simbólicas de los CCO, el presente artículo procura interrogar la especificidad de esa modalidad de okupación urbana con respecto a la producción del hábitat. Para ello, estudia dos casos ubicados en ciudades argentinas: el Centro Kultural Independiente (CKI) (Rosario, 1997-1998) y el Centro Kultural Trivenchi (CKT) (Buenos Aires, 2001-actualidad). La investigación emplea un enfoque metodológico cualitativo, que triangula entrevistas en profundidad, materiales audiovisuales y documentos escritos. La arquitectura del texto analiza los casos del CKI y el CKT a través de cuatro nudos comparativos: los contextos de las okupaciones, los procesos de adecuación material de los espacios, las prácticas y significaciones de sus participantes y los conflictos con los gobiernos urbanos. Se concluye que los CCO producen hábitat mediante una apropiación espacial diferencial que, vehiculizada por dimensiones culturales y artísticas, posibilita la apertura y la puesta en circulación social de espacios clausurados por la reestructuración capitalista de las ciudades.

Abstract: The phenomenon of urban squatting entails social experiences of appropriation and use of abandoned buildings. Concurrently, the Centros Culturales Okupa (CCO) constitute specific forms of urban squatting articulated around cultural and artistic practices. Based on the analysis of the material and socio-symbolic dimensions of CCOs, this article aims to interrogate the specificity of this type of urban squatting regarding the production of habitat. In order to do that, the investigation draws on two case studies located in Argentinian cities: Centro Kultural Independiente (CKI) (Rosario, 1997-1998) and Centro Kultural Trivenchi (CKT) (Buenos Aires, 2001-present). The research uses a qualitative methodological approach, which triangulates in-depth interviews, audiovisual materials, and written documents. The architecture of the text analyzes the cases of the CKI and the CKT through four comparative nodes: the contexts of squatting, the processes of material adaptation of space, the practices and significations of the participants, and the conflicts with the urban governments. It is concluded that CCOs produce habitat through a differential spatial appropriation that, driven by cultural and artistic dimensions, enables the opening and putting into social circulation of spaces closed by the capitalist restructuring of cities.

Introduction: Complete mesocolic excision (CME) consists in the dissection on embryologic planes in order to achieve a complete resection of the mesocolic envelope and performing a central vascular ligation (CVL) with a D3 lymphadenectomy which is not routinely done for standard right colectomies. CME has been associated with better overall survival and disease-free survival in comparison with conventional surgery in retrospective studies. However, there is no data on its implementation in Chile. The aim of this study is to assess the perioperative results of the implementation of CME in our center. Methods: A retrospective cohort study was conducted. Consecutive patients undergoing a laparoscopic right hemicolectomy with CME-CVL between January 2022 and June 2023 were included. Demographic, perioperative, postoperative and histopathological data were collected. Results were analyzed using descriptive statistics. Results: During the study period, 34 patients underwent CME; 29 of them underwent laparoscopic CMECVL (median age 66 (57-76) and 15 (52%) female). The median operating time was 202,9 minutes. There were no cases of conversion, anastomotic leakage or mortality. There was morbidity in 9 cases (31%) and one of these (3,4%) was a Clavien-Dindo III morbidity (reoperation due to a Pfannenstiel haematoma). There were no intraoperative vascular injuries. The median length of stay was 3 days. Twelve cases (41%) were stage II and 8(28%) stage III. The median number of lymph nodes harvested was 23(18-28). Conclusion: This series demonstrate that the implementation of laparoscopic CME-CVL for right and transverse colon cancer is feasible in centers with experience in advanced laparoscopic colorectal cancer.

Resumen Introducción: La técnica de resección completa del mesocolon (RCM) en la hemicolectomía derecha consiste en la disección por planos embriológicos para lograr la resección completa del envoltorio mesocolónico, además de una ligadura vascular central (LVC) con linfadenectomía D3, que no se realiza normalmente con la técnica estándar. Esta técnica se asocia a mejores resultados de sobrevida global y libre de enfermedad que la cirugía convencional en trabajos retrospectivos. Sin embargo, no existen datos de su implementación a nivel nacional. El objetivo de este estudio es evaluar los resultados perioperatorios de la implementación del RCM en un centro universitario en nuestro medio. Materiales y Método: Estudio retrospectivo de cohorte de pacientes consecutivos sometidos a hemicolectomía derecha laparoscópica con técnica de RCM-LVC entre Enero 2022 y Junio 2023. Se recopilaron variables demográficas, perioperatorias, postoperatorias e histopatológicas. Los resultados se analizaron utilizando estadística descriptiva. Resultados: En el periodo, 29 pacientes se sometieron a RCM laparoscópica (mediana de edad 66(57-76) y 15(52%) sexo femenino). La mediana del tiempo quirúrgico fue 202,9 minutos. No hubo casos de conversión, filtración anastomótica, ni mortalidad. Hubo morbilidad en 9 casos (31%) y de estos solo 1(3,4%) fue Clavien-Dindo III (hematoma Pfannenstiel reintervenido). No hubo lesiones vasculares intraoperatorias. Mediana de hospitalización de 3 días. Doce casos (41%) eran etapa II y 8(28%) etapa III. La mediana de linfonodos resecados fue 23(18-28). Conclusión: Esta serie demuestra que la implementación de la RCM-LVC por vía laparoscópica para el tratamiento del cáncer de colon derecho y transverso es factible en centros con experiencia en cirugía colorrectal laparoscópica avanzada.

RESUMEN En la carrera Estomatología, las relaciones interdisciplinarias entre las asignaturas clínicas y la Farmacología resultan necesarias para lograr en los estudiantes un mayor desarrollo de habilidades teóricas y prácticas dirigidas la prescripción racional de medicamentos de uso estomatológico. La presente investigación tuvo como objetivo describir dos vías para lograr lo antes expuesto. Las vías propuestas resultaron ser: la identificación de los nodos potenciales de articulación interdisciplinaria entre estas unidades curriculares y la interrelación de métodos de enseñanzas. Se concluye que ambas propuestas constituyen vías concretas para el establecimiento y desarrollo de las relaciones interdisciplinarias entre las asignaturas clínicas y la Farmacología en la carrera Estomatología.

ABSTRACT In the Stomatology degree, interdisciplinary relationships between clinical subjects and Pharmacology are necessary to achieve in students a greater development of theoretical and practical skills aimed at the rational prescription of medications for stomatological use. The objective of this research was to describe two ways to achieve the above. The proposed paths turned out to be: the identification of potential nodes of interdisciplinary articulation between these curricular units and the interrelation of teaching methods. It is concluded that both proposals constitute concrete ways for the establishment and development of interdisciplinary relationships between clinical subjects and Pharmacology in the Stomatology career.

Abstract: The presence of religion in the curriculum of a public school system is a controversial topic. This paper offers a hermeneutic analysis of Decree 924/83, the primary regulatory instrument overseeing the role of religion in schools and higher education in Chile. The aim is to uncover its principal challenges and propose new perspectives grounded in philosophical arguments. Specifically, three critical nodes are identified that arise from the interpretation of Decree 924/83 in its text and implementation: exclusivism, confessionalism, and (possibly) religious illiteracy. To overcome these challenges, a new approach is proposed, suggesting that religious classes be presented as a universal, mandatory, and non-denominational educational asset. Finally, we offer some implications for future academic research and public policy regarding the presence of religious education in the Chilean school system.

Resumen: La presencia de la religión en el currículum de un sistema escolar público es un tema controvertido. Este artículo propone una hermenéutica de la principal herramienta normativa que regula la presencia de la religión en las escuelas y colegios de Chile, el Decreto 924/83, para identificar sus principales aspectos problemáticos y, a través de argumentos filosóficos, vislumbrar nuevas perspectivas. Se identifican específicamente tres puntos críticos que surgen de la interpretación del Decreto 924/83 en su texto y puesta en práctica: exclusivismo, confesionalismo y (posible) analfabetismo religioso. Para superar estos problemas, se propone un nuevo abordaje que plantea la clase de religión como un bien educativo universal, obligatorio y no confesional. En conclusión, se ofrecen algunas implicancias para futuras investigaciones académicas y las políticas públicas respecto de la presencia de la clase de religión en el sistema escolar de Chile.